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Surface cysteine to serine substitutions in IL-18 reduce aggregation and enhance activity
Authors: Jirakrit Saetang, Niran Roongsawang, Surasak Sangkhathat, Supayang Piyawan Voravuthikunchai, Natnaree Sangkaew, Napat Prompat, Teerapol Srichana, Varomyalin Tipmanee
Journal: PeerJ
PubMed ID: 35811828
Doi: 10.7717/peerj.13626
Products & Services: Plasmid DNA Preparation   
Expanding the DNA-encoded library toolbox: identifying small molecules targeting RNA
Authors: Qiuxia Chen, You Li, Chunrong Lin, Liu Chen, Hao Luo, Shuai Xia, Chuan Liu, Xuemin Cheng, Chengzhong Liu, Jin Li, Dengfeng Dou
Journal: Nucleic Acids Res
PubMed ID: 35288754
Doi: 10.1093/nar/gkac173
Products & Services: Bacterial Expression   
The role of CFA/I in adherence and toxin delivery by ETEC expressing multiple colonization factors in the human enteroid model
Authors: Emily M Smith, Christen L Grassel, Antonia Papadimas, Jennifer Foulke-Abel, Eileen M Barry
Journal: PLoS Negl Trop Dis
PubMed ID: 35881640
Doi: 10.1371/journal.pntd.0010638
Insight into bacterial community profiles of oil shale and sandstone in ordos basin by culture-dependent and culture-independent methods
Authors: Fengdan Wei, Rui Xu, Yuanyuan Xu, Tao Cheng, Yanling Ma
Journal: J Environ Sci Health A Tox Hazard Subst Environ Eng
PubMed ID: 35903918
Doi: 10.1080/10934529.2022.2105631
Products & Services: DNA Sequencing   
Enhancing epitope of PEDV spike protein
Authors: Techit Thavorasak, Monrat Chulanetra, Kittirat Glab-Ampai, Kodchakorn Mahasongkram, Nawannaporn Sae-Lim, Karsidete Teeranitayatarn, Thaweesak Songserm, Rungrueang Yodsheewan, Dachrit Nilubol, Wanpen Chaicumpa, Nitat Sookrung
Journal: Front Microbiol
PubMed ID: 35935230
Doi: 10.3389/fmicb.2022.933249
Products & Services: Catalog Peptides   
Self-Assembling Protein Surfaces for Capture of Cell-Free-Synthesized Proteins
Authors: Ella Lucille Thornton, Sarah Maria Paterson, Zoe Gidden, Mathew H Horrocks, Nadanai Laohakunakorn, Lynne Regan
Journal: Front Bioeng Biotechnol
PubMed ID: 35875503
Doi: 10.3389/fbioe.2022.915035
Products & Services: Catalog Antibody   
Conformational fingerprinting of allosteric modulators in metabotropic glutamate receptor 2
Authors: Brandon Wey-Hung Liauw, Arash Foroutan, Michael R Schamber, Weifeng Lu, Hamid Samareh Afsari, Reza Vafabakhsh
Journal: Elife
PubMed ID: 35775730
Doi: 10.7554/eLife.78982
Products & Services: DNA Sequencing   
Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains
Authors: James Brett Case, Samantha Mackin, John M Errico, Zhenlu Chong, Emily A Madden, Bradley Whitener, Barbara Guarino, Michael A Schmid, Kim Rosenthal, Kuishu Ren, Ha V Dang, Gyorgy Snell, Ana Jung, Lindsay Droit, Scott A Handley, Peter J Halfmann, Yoshihiro Kawaoka, James E Crowe, Daved H Fremont, Herbert W Virgin, Yueh-Ming Loo, Mark T Esser, Lisa A Purcell, Davide Corti, Michael S Diamond
Journal: Nat Commun
PubMed ID: 35780162
Doi: 10.1038/s41467-022-31615-7
Products & Services: Polyclonal Antibody Services   
PTPRO knockdown protects against inflammation in hemorrhage shock-induced lung injury involving the NF-κB signaling pathway
Authors: Zhirong Huan, Ying Tang, Ce Xu, Jimin Cai, Hao Yao, Yan Wang, Fanyu Bu, Xin Ge
Journal: Respir Res
PubMed ID: 35906634
Doi: 10.1186/s12931-022-02118-2
Products & Services: Mammalian Expression   
Membrane fluidity, composition, and charge affect the activity and selectivity of the AMP ascaphin-8
Authors: Adriana Morales-Martínez, Brandt Bertrand, Juan M Hernández-Meza, Ramón Garduño-Juárez, Jesús Silva-Sanchez, Carlos Munoz-Garay
Journal: Biophys J
PubMed ID: 35842753
Doi: 10.1016/j.bpj.2022.07.018
Products & Services: GenCrispr Cas9 Genome Editing   
Construction of a T7 phage display nanobody library for bio-panning and identification of chicken dendritic cell-specific binding nanobodies
Authors: Hai Xu, Ling Li, Bihua Deng, Weiming Hong, Ruiting Li, Zijie Guo, Jibo Hou, Roshini Govinden, Hafizah Y Chenia
Journal: Sci Rep
PubMed ID: 35840654
Doi: 10.1038/s41598-022-16378-x
Products & Services: DNA Sequencing   
Ca attenuates nucleation activity of leiomodin
Authors: Garry E Smith, Dmitri Tolkatchev, Cristina Risi, Madison Little, Carol C Gregorio, Vitold E Galkin, Alla S Kostyukova
Journal: Protein Sci
PubMed ID: 35762710
Doi: 10.1002/pro.4358
A Single Vaccination of Chimeric Bivalent Virus-Like Particle Vaccine Confers Protection Against H9N2 and H3N2 Avian Influenza in Commercial Broilers and Allows a Strategy of Differentiating Infected from Vaccinated Animals
Authors: Yi-Xue Sun, Zheng-Rong Li, Peng-Ju Zhang, Jin-Hong Han, Hai-Yang Di, Jia-Yi Qin, Yan-Long Cong
Journal: Front Immunol
PubMed ID: 35874682
Doi: 10.3389/fimmu.2022.902515
Products & Services: Gene Synthesis   
Engineering a tunable bicistronic TetR autoregulation expression system in
Authors: Monica Bertucci, Ky Ariano, Meg Zumsteg, Paul Schweiger
Journal: PeerJ
PubMed ID: 35873911
Doi: 10.7717/peerj.13639
Products & Services: PCR Cloning and Subcloning   
Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus
Authors: Francesco Aulicino, Martin Pelosse, Christine Toelzer, Julien Capin, Erwin Ilegems, Parisa Meysami, Ruth Rollarson, Per-Olof Berggren, Mark Simon Dillingham, Christiane Schaffitzel, Moin A Saleem, Gavin I Welsh, Imre Berger
Journal: Nucleic Acids Res
PubMed ID: 35801912
Doi: 10.1093/nar/gkac587
Products & Services: Synthetic sgRNA and crRNA Service   
Durability of the Neutralizing Antibody Response to mRNA Booster Vaccination Against SARS-CoV-2 BA2121 and BA4/5 Variants
Authors: Panke Qu, Julia N Faraone, John P Evans, Yi-Min Zheng, Claire Carlin, Gerard Lozanski, Linda J Saif, Eugene M Oltz, Richard J Gumina, Shan-Lu Liu
Journal: biorxiv
PubMed ID: 35898337
Doi: 10.1101/2022.07.21.501010
Products & Services: Plasmid DNA Preparation   
Impact of the temperature on the interactions between common variants of the SARS-CoV-2 receptor binding domain and the human ACE2
Authors: Catherine Forest-Nault, Izel Koyuturk, Jimmy Gaudreault, Alex Pelletier, Denis L'Abbé, Brian Cass, Louis Bisson, Alina Burlacu, Laurence Delafosse, Matthew Stuible, Olivier Henry, Gregory De Crescenzo, Yves Durocher
Journal: Sci Rep
PubMed ID: 35798770
Doi: 10.1038/s41598-022-15215-5
Products & Services: Mammalian Expression   
Limited Correlation between SARS-CoV-2 Serologic Assays for Identification of High-Titer COVID-19 Convalescent Plasma Using FDA Thresholds
Authors: Nicholas E Larkey, Radwa Ewaisha, Michael A Lasho, Matthew M Roforth, Dane Granger, Calvin R Jerde, Liang Wu, Amy Gorsh, Stephen A Klassen, Jonathon W Senefeld, Michael J Joyner, Nikola A Baumann, Elitza S Theel, John R Mills
Journal: Microbiol Spectr
PubMed ID: 35862939
Doi: 10.1128/spectrum.01154-22
Pro-Survival Factor EDEM3 Confers Therapy Resistance in Prostate Cancer
Authors: Emma Scott, Rebecca Garnham, Kathleen Cheung, Adam Duxfield, David J Elliott, Jennifer Munkley
Journal: Int J Mol Sci
PubMed ID: 35897761
Doi: 10.3390/ijms23158184
Products & Services: Custom Vector Construction   
An adaptable platform for in-house hepatitis C serology
Authors: Jannie Pedersen, Irène Pegha Moukandja, Stella Ndidi, Anna-Louise Sørensen, Ismaël Hervé Koumakpayi, Jean-Bernard Lekana-Douki, Marie-Louise Vachon, Nina Weis, Gary Kobinger, Hugues Fausther-Bovendo
Journal: J Virol Methods
PubMed ID: 35850366
Doi: 10.1016/j.jviromet.2022.114586
Products & Services: Custom Vector Construction   
Physical activity and antibody persistence 6 months after the second dose of CoronaVac in immunocompromised patients
Authors: Bruno Gualano, Ítalo Ribeiro Lemes, Rafael Pires da Silva, Ana Jéssica Pinto, Bruna Caruso Mazzolani, Fabiana Infante Smaira, Sofia Mendes Sieczkowska, Nádia Emi Aikawa, Sandra Pasoto, Ana Cristina Medeiros-Ribeiro, Carla Saad, Emily Yuk, Clovis Silva, Paul Swinton, Pedro Curi Hallal, Hamilton Roschel, Eloisa Bonfa
Journal: Scand J Med Sci Sports
PubMed ID: 35844042
Doi: 10.1111/sms.14213
High Mobility Group Protein B1 Decreases Surface Localization of PD-1 to Augment T-cell Activation
Authors: Qun Gao, Shumin Wang, Feng Li, Jingyao Lian, Shaoyan Cheng, Dongli Yue, Zhen Zhang, Shasha Liu, Feifei Ren, Daiqun Zhang, Shengdian Wang, Liping Wang, Yi Zhang
Journal: Cancer Immunol Res
PubMed ID: 35580259
Doi: 10.1158/2326-6066.CIR-21-0652
Products & Services: Recombinant Proteins   
Structures of the T cell potassium channel Kv13 with immunoglobulin modulators
Authors: Purushotham Selvakumar, Ana I Fernández-Mariño, Nandish Khanra, Changhao He, Alice J Paquette, Bing Wang, Ruiqi Huang, Vaughn V Smider, William J Rice, Kenton J Swartz, Joel R Meyerson
Journal: Nat Commun
PubMed ID: 35788586
Doi: 10.1038/s41467-022-31285-5
Products & Services: Plasmid DNA Preparation   
Kalium channelrhodopsins are natural light-gated potassium channels that mediate optogenetic inhibition
Authors: Elena G Govorunova , Yueyang Gou , Oleg A Sineshchekov , Hai Li , Xiaoyu Lu , Yumei Wang , Leonid S Brown , François St-Pierre , Mingshan Xue , John L Spudich
Journal: Nature neuroscience
PubMed ID: 35726059
Doi: 10.1038/s41593-022-01094-6
Products & Services: Gene Synthesis   
Core cysteine residues in the Plasminogen-Apple-Nematode (PAN) domain are critical for HGF/c-MET signaling
Authors: Debjani Pal , Kuntal De , Carly M Shanks , Kai Feng , Timothy B Yates , Jennifer Morrell-Falvey , Russell B Davidson , Jerry M Parks , Wellington Muchero
Journal: Commun Biol
PubMed ID: 35778602
Doi: 10.1038/s42003-022-03582-8
Hsp70 inhibits the replication of Fowl Adenovirous serotype 4 by suppressing viral Hexon with the assistance of DnaJC7
Authors: Jie Cao , Shuhui Liu , Meng Liu , Shuaiwen Wang , Zhenwei Bi , Wentao Fan , Zhiyu Shi , Suquan Song , Liping Yan
Journal: J Virol
PubMed ID: 35852354
Doi: 10.1128/jvi.00807-22
Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker
Authors: Aslan Mansurov , Peyman Hosseinchi, Kevin Chang, Abigail L Lauterbach, Laura T Gray , Aaron T Alpar , Erica Budina , Anna J Slezak , Seounghun Kang, Shijie Cao, Ani Solanki , Suzana Gomes , John-Michael Williford, Melody A Swartz , Juan L Mendoza , Jun Ishihara , Jeffrey A Hubbell
Journal: Nat Biomed Eng
PubMed ID: 35534574
Doi: 10.1038/s41551-022-00888-0
Products & Services: Mammalian Expression   
Identification of nucleoside monophosphates and their epigenetic modifications using an engineered nanopore.
Authors: Yuqin Wang , Shanyu Zhang , Wendong Jia ,Pingping Fan , Liying Wang , Xinyue Li , Jialu Chen , Zhenyuan Cao , Xiaoyu Du , Yao Liu , Kefan Wang , Chengzhen Hu , Jinyue Zhang , Jun Hu , Panke Zhang , Hong-Yuan Chen , Shuo Huang
Journal: Nat Nanotechnol
PubMed ID: 35851382
Doi: 10.1038/s41565-022-01169-2
Products & Services: Gene Synthesis   
Oncolytic adenovirus with MUC16-BiTE shows enhanced antitumor immune response by reversing the tumor microenvironment in PDX model of ovarian cancer
Authors: Qiuman Wang , Xinyue Ma , Huan Wu , Chen Zhao 1, Jingying Chen , Rongrong Li , Shi Yan , Yingwei Li , Qing Zhang , Kun Song , Cunzhong Yuan , Beihua Kong
Journal: Oncoimmunology
PubMed ID: 35800156
Doi: 10.1080/2162402X.2022.2096362 Free PMC article
Developing and validating SARS-CoV-2 assays for nonhuman primate surveillance
Authors: JoAnn Yee, Amanda Carpenter, Peter Nham, Bryson Halley, Koen K A Van Rompay, Jeffrey Roberts
Journal: J Med Primatol
PubMed ID: 35794847
Doi: 10.1111/jmp.12604
Products & Services: Mammalian Expression   
CaMKII Inhibition Attenuates Distinct Gain-of-Function Effects Produced by Mutant Nav16 Channels and Reduces Neuronal Excitability
Authors: Agnes S Zybura, Firoj K Sahoo, Andy Hudmon, Theodore R Cummins
Journal: Cells
PubMed ID: 35805192
Doi: 10.3390/cells11132108
Products & Services: Mammalian Expression   
Efficient multiplex CRISPR/Cpf1 (Cas12a) genome editing system in Aspergillus aculeatus TBRC 277
Authors: Dede Abdulrachman, Verawat Champreda, Lily Eurwilaichitr, Duriya Chantasingh, Kusol Pootanakit
Journal: J Biotechnol
PubMed ID: 35788357
Doi: 10.1016/j.jbiotec.2022.06.011
Products & Services: Synthetic sgRNA and crRNA Service   
Ancestrally Reconstructed von Willebrand Factor Reveals Evidence for Trench Warfare Coevolution between Opossums and Pit Vipers
Authors: Danielle H Drabeck, Alexandra Rucavado, Erika Hingst-Zaher, Antony Dean, Sharon A Jansa
Journal: Mol Biol Evol
PubMed ID: 35723968
Doi: 10.1093/molbev/msac140
Products & Services: Gene Synthesis   
Calcium responses to external mechanical stimuli in the multicellular stage of Dictyostelium discoideum
Authors: Hidenori Hashimura, Yusuke V Morimoto, Yusei Hirayama, Masahiro Ueda
Journal: Sci Rep
PubMed ID: 35859163
Doi: 10.1038/s41598-022-16774-3
Products & Services: GenParts™ DNA Fragments   
miR-301b-5p and its target gene nfatc2ip regulate inflammatory responses in the liver of rainbow trout (Oncorhynchus mykiss) under high temperature stress
Authors: Tianqing Huang, Wei Gu, Enhui Liu, Bingqian Wang, Gaochao Wang, Fulin Dong, Fuyuan Guo, Wenlong Jiao, Yanchun Sun, Xiance Wang, Shanwei Li, Gefeng Xu
Journal: Ecotoxicol Environ Saf
PubMed ID: 35901591
Doi: 10.1016/j.ecoenv.2022.113915
Products & Services: Plasmid DNA Preparation   
An immunodetection assay developed using cobra cytotoxin-specific antibodies: Potential diagnostics for cobra envenoming
Authors: Hui Ling Ong, Choo Hock Tan, Louisa Pernee Lee, Sook Mei Khor, Kae Yi Tan
Journal: Toxicon
PubMed ID: 35868411
Doi: 10.1016/j.toxicon.2022.07.010
Products & Services: Catalog Antibody   
A Single Dose of Anti-HBsAg Antibody-Encoding mRNA-LNPs Suppressed HBsAg Expression: a Potential Cure of Chronic Hepatitis B Virus Infection
Authors: Binfan Chen, Yuchen Chen, Jian Li, Chunyu Wang, Wenping Song, Yumei Wen, Jinzhong Lin, Yanling Wu, Tianlei Ying
Journal: MBio
PubMed ID: 35862767
Doi: 10.1128/mbio.01612-22
Products & Services: Catalog Antibody   
Phage defence by deaminase-mediated depletion of deoxynucleotides in bacteria
Authors: Brian Y Hsueh, Geoffrey B Severin, Clinton A Elg, Evan J Waldron, Abhiruchi Kant, Alex J Wessel, John A Dover, Christopher R Rhoades, Benjamin J Ridenhour, Kristin N Parent, Matthew B Neiditch, Janani Ravi, Eva M Top, Christopher M Waters
Journal: Nat Microbiol
PubMed ID: 35817890
Doi: 10.1038/s41564-022-01162-4
Products & Services: Catalog Antibody   
Sequence grammar underlying the unfolding and phase separation of globular proteins
Authors: Kiersten M Ruff, Yoon Hee Choi, Dezerae Cox, Angelique R Ormsby, Yoochan Myung, David B Ascher, Sheena E Radford, Rohit V Pappu, Danny M Hatters
Journal: Mol Cell
PubMed ID: 35853451
Doi: 10.1016/j.molcel.2022.06.024
Products & Services: Custom Vector Construction   
Screening circular RNAs with functional potential using the RfxCas13d/BSJ-gRNA system
Authors: Siqi Li, Hao Wu, Ling-Ling Chen
Journal: Nat Protoc
PubMed ID: 35831613
Doi: 10.1038/s41596-022-00715-5
Products & Services: Custom DNA/RNA Oligos   
SARS-CoV-2 Epitopes following Infection and Vaccination Overlap Known Neutralizing Antibody Sites
Authors: Li Yang, Te Liang, Lane M Pierson, Hongye Wang, Jesse K Fletcher, Shu Wang, Duran Bao, Lili Zhang, Zhen Huang, Wenshu Zheng, Xiaomei Zhang, Heewon Park, Yuwen Li, James E Robinson, Amy K Feehan, Christopher J Lyon, Jing Cao, Lisa A Morici, Chenzhong Li, Chad J Roy, Xiaobo Yu, Tony Hu
Journal: Research (Wash D C)
PubMed ID: 35928300
Doi: 10.34133/2022/9769803
Products & Services: Catalog Peptides   
Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut
Authors: Víctor Taleb, Qinghua Liao, Yoshiki Narimatsu, Ana García-García, Ismael Compañón, Rafael Junqueira Borges, Andrés Manuel González-Ramírez, Francisco Corzana, Henrik Clausen, Carme Rovira, Ramon Hurtado-Guerrero
Journal: Nat Commun
PubMed ID: 35882872
Doi: 10.1038/s41467-022-32021-9
Products & Services: Mutagenesis Services   
Phage Particles of Controlled Length and Genome for Targeted Glioblastoma Imaging and Therapeutic Delivery
Authors: Uyanga Tsedev, Ching-Wei Lin, Gaelen T Hess, Jann N Sarkaria, Fred C Lam, Angela M Belcher
Journal: ACS Nano
PubMed ID: 35830573
Doi: 10.1021/acsnano.1c08720
Products & Services: Plasmid DNA Preparation   
The Unfolded-Protein Response Triggers the Arthropod Immune Deficiency Pathway
Authors: Lindsay C Sidak-Loftis, Kristin L Rosche, Natasha Pence, Jessica K Ujczo, Joanna Hurtado, Elis A Fisk, Alan G Goodman, Susan M Noh, John W Peters, Dana K Shaw
Journal: MBio
PubMed ID: 35862781
Doi: 10.1128/mbio.00703-22
Products & Services: Mammalian Expression   
Conformational landscape of the yeast SAGA complex as revealed by cryo-EM
Authors: Diana Vasyliuk, Joeseph Felt, Ellen D Zhong, Bonnie Berger, Joseph H Davis, Calvin K Yip
Journal: Sci Rep
PubMed ID: 35853968
Doi: 10.1038/s41598-022-16391-0
Protective effects of small heat shock proteins in Daphnia magna against heavy metal exposure
Authors: Muyi Li, Ting Tang, Fengyu Yuan, Yuming Zhang, Fengchao Li, Fengsong Liu
Journal: Sci Total Environ
PubMed ID: 35907523
Doi: 10.1016/j.scitotenv.2022.157565
Development and applications of a TaqMan based quantitative real-time PCR for the rapid detection of Pigeon circovirus (PiCV)
Authors: Babu K Nath, Shubhagata Das, Tridip Das, Jade K Forwood, Shane R Raidal
Journal: J Virol Methods
PubMed ID: 35870671
Doi: 10.1016/j.jviromet.2022.114588
Cholesterol Deprivation Drives DHEA Biosynthesis in Human Adrenals
Authors: Emanuele Pignatti, Emre Murat Altinkilic, Konstantin Bräutigam, Michael Grössl, Aurel Perren, Mihaela Zavolan, Christa E Flück
Journal: Endocrinology
PubMed ID: 35583599
Doi: 10.1210/endocr/bqac076
Products & Services: Plasmid DNA Preparation   
An Engineered λ Phage Enables Enhanced and Strain-Specific Killing of Enterohemorrhagic Escherichia coli
Authors: Menglu Jin, Jingchao Chen, Xueyang Zhao, Guoru Hu, Hailei Wang, Zhi Liu, Wei-Hua Chen
Journal: Microbiol Spectr
PubMed ID: 35876591
Doi: 10.1128/spectrum.01271-22
Products & Services: Gene Synthesis   

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