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Design, Construction, and Validation of a Yeast-Displayed Chemically Expanded Antibody Library

Authors: Arlinda Rezhdo, Rebecca L Hershman, James A Van Deventer

Journal: biorxiv

PubMed ID: 38853888

Doi: 10.1101/2024.05.29.596443

Products & Services: Proteins, Expression, Isolation and Analysis

Intranasal vaccination with an NDV-vectored SARS-CoV-2 vaccine protects against Delta and Omicron challenges

Authors: Bryce M Warner, Jacob G E Yates, Robert Vendramelli, Thang Truong, Courtney Meilleur, Lily Chan, Alexander Leacy, Phuc H Pham, Yanlong Pei, Leonardo Susta, Sarah K Wootton, Darwyn Kobasa

Journal: npj Vaccines

PubMed ID: 38782986

Doi: 10.1038/s41541-024-00870-8

Products & Services: Proteins, Expression, Isolation and Analysis

Development and characterization of an antibody that recognizes influenza virus N1 neuraminidases

Authors: Nan Chen, Renxi Wang, Wanlu Zhu, Xiangjun Hao, Jing Wang, Guojiang Chen, ChunXia Qiao, Xinying Li, Chenghua Liu, Beifen Shen, Jiannan Feng, Lihui Chai, Zuyin Yu, He Xiao

Journal: PLoS ONE

PubMed ID: 38723016

Doi: 10.1371/journal.pone.0302865

Products & Services: Proteins, Expression, Isolation and Analysis

Temperature-dependent iron motion in extremophile rubredoxins - no need for 'corresponding states'

Authors: Francis E Jenney, Hongxin Wang, Simon J George, Jin Xiong, Yisong Guo, Leland B Gee, Juan José Marizcurrena, Susana Castro-Sowinski, Anna Staskiewicz, Yoshitaka Yoda, Michael Y Hu, Kenji Tamasaku, Nobumoto Nagasawa, Lei Li, Hiroaki Matsuura, Tzanko Doukov, Stephen P Cramer

Journal: Sci Rep

PubMed ID: 38806591

Doi: 10.1038/s41598-024-62261-2

Products & Services: Proteins, Expression, Isolation and Analysis

Stacked mutations in wheat homologues of rice SEMI-DWARF1 confer a novel semi-dwarf phenotype

Authors: Barbora Ndreca, Alison Huttly, Sajida Bibi, Carlos Bayon, George Lund, Joshua Ham, Rocío Alarcón-Reverte, John Addy, Danuše Tarkowská, Stephen Pearce, Peter Hedden, Stephen G Thomas, Andrew L Phillips

Journal: BMC Plant Biol

PubMed ID: 38724935

Doi: 10.1186/s12870-024-05098-1

Products & Services: Mutant Libraries

Accuracy of Anti-SARS-CoV-2 Antibody in Comparison with Surrogate Viral Neutralization Test in Persons Living with HIV, Systemic Lupus Erythematosus, and Chronic Kidney Disease

Authors: Marita Restie Tiara, Chrisan Bimo Prayuda, Tara Titian Maulidya, Hofiya Djauhari, Dadang Suhendar, Rudi Wisaksana, Laniyati Hamijoyo, Rudi Supriyadi, Agnes Rengga Indrati, Bachti Alisjahbana

Journal: Vaccines (Basel)

PubMed ID: 38793809

Doi: 10.3390/vaccines12050558

Products & Services: Serology SARS-Cov-2 detection kits

Acts as a Positive Regulator of Secondary Cell Wall Synthesis in Sudan Grass ( S)

Authors: Yanzhong Huang, Juanzi Wu, Jianyu Lin, Zhiwei Liu, Zhengfeng Mao, Chen Qian, Xiaoxian Zhong

Journal: Plants (Basel)

PubMed ID: 38794423

Doi: 10.3390/plants13101352

Products & Services: Gene Synthesis

Development and validation of an HILIC/MS/MS method for determination of nusinersen in rabbit plasma

Authors: Xiao Zhang, Chunjie Sha, Wei Zhang, Fengjuan Zhao, Mingli Zhu, Guangyi Leng, Wanhui Liu

Journal: Heliyon

PubMed ID: 38799737

Doi: 10.1016/j.heliyon.2024.e31213

Products & Services: Gene Synthesis

Effect of three oral pathogens on the TMA-TMAO metabolic pathway

Authors: Xixuan Wang, Liyuan Chen, Ye Teng, Weige Xie, Lingyan Huang, Juan Wu, Hongwei Wang, Sijing Xie

Journal: Front Cell Infect Microbiol

PubMed ID: 38836053

Doi: 10.3389/fcimb.2024.1413787

Products & Services: PCR Cloning and Subcloning

4-Octyl Itaconate Attenuates Neuroinflammation in Experimental Autoimmune Encephalomyelitis Via Regulating Microglia

Authors: Ning Zhao, Ming Yi, Lin-Jie Zhang, Qiu-Xia Zhang, Li Yang

Journal: Inflammation

PubMed ID: 38761250

Doi: 10.1007/s10753-024-02050-1

Products & Services: Catalog Peptides

Design of antiviral AGO2-dependent short hairpin RNAs

Authors: Yuanyuan Bie, Jieling Zhang, Jiyao Chen, Yumin Zhang, Muhan Huang, Leike Zhang, Xi Zhou, Yang Qiu

Journal: Virol Sin

PubMed ID: 38734183

Doi: 10.1016/j.virs.2024.05.001

Products & Services: Gene Synthesis

The autophagy protein Atg9 functions in glia and contributes to parkinsonian symptoms in a model of Parkinson's disease

Authors: Shuanglong Yi, Linfang Wang, Margaret S Ho, Shiping Zhang

Journal: Neural Regen Res

PubMed ID: 37862221

Doi: 10.4103/1673-5374.382259

Products & Services: Molecular Biology Reagents

Exosome-derived circUPF2 enhances resistance to targeted therapy by redeploying ferroptosis sensitivity in hepatocellular carcinoma

Authors: Feng-Lin Dong, Zong-Zhen Xu, Ying-Qiao Wang, Tao Li, Xin Wang, Jie Li

Journal: J Nanobiotechnology

PubMed ID: 38811968

Doi: 10.1186/s12951-024-02582-6

Products & Services: Catalog Antibody

Graph-Based Pangenome of Actinidia chinensis Reveals Structural Variations Mediating Fruit Degreening

Authors: Yingzhen Wang, Pengwei Li, Yanyan Zhu, Feng Zhang, Sijia Zhang, Yan He, Ying Wu, Yunzhi Lin, Hongtao Wang, Wangmei Ren, Lihuan Wang, Ying Yang, Runze Wang, Pengpeng Zheng, Yongsheng Liu, Songhu Wang, Junyang Yue

Journal: Adv Sci (Weinh)

PubMed ID: 38757662

Doi: 10.1002/advs.202400322

Products & Services: Polyclonal Antibody Services

Construction and immune effect evaluation of the S protein heptad repeat-based nanoparticle vaccine against porcine epidemic diarrhea virus

Authors: Dan Yang, Xinglin Wang, Xu Yang, Shanshan Qi, Feiyu Zhao, Donghua Guo, Chunqiu Li, Qinghe Zhu, Xiaoxu Xing, Yang Cao, Dongbo Sun

Journal: Virology

PubMed ID: 38801794

Doi: 10.1016/j.virol.2024.110113

Products & Services: Molecular Biology Reagents

An Active and Versatile Electron Transport System for Cytochrome P450 Monooxygenases from the Alkane Degrading Organism Acinetobacter sp OC4

Authors: Fabian Peter Josef Schultes, Leon Welter, Doreen Hufnagel, Melanie Heghmanns, Müge Kasanmascheff, Carolin Muegge

Journal: Chembiochem

PubMed ID: 38787654

Doi: 10.1002/cbic.202400098

Products & Services: Molecular Biology Reagents

The interaction of GRP78 and Zika virus E and NS1 proteins occurs in a chaperone-client manner

Authors: Wannapa Sornjai, Ploenphit Promma, Suphansa Priewkhiew, Suwipa Ramphan, Janejira Jaratsittisin, Pailin Jinagool, Nitwara Wikan, Michael Greenwood, David Murphy, Duncan R Smith

Journal: Sci Rep

PubMed ID: 38710792

Doi: 10.1038/s41598-024-61195-z

Products & Services: Molecular Biology Reagents

Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors

Authors: Hongjin Zhang, Guohao Lin, Suyun Jia, Jianbo Wu, Ying Zhang, Yanxin Tao, Weixue Huang, Meiru Song, Ke Ding, Dawei Ma, Mengyang Fan

Journal: Bioorg Chem

PubMed ID: 38761706

Doi: 10.1016/j.bioorg.2024.107456

Products & Services: Recombinant Proteins

Kanglexin counters vascular smooth muscle cell dedifferentiation and associated arteriosclerosis through inhibiting PDGFR

Authors: Shuang Yang, Yixiu Zhao, Shifeng Cao, Xinxin Liu, Min Feng, Yi Chen, Chunyue Ma, Tingting Zhan, Qi Zhang, Honglin Jia, Yu Zhao, Ming Tong, Yuanyuan Yu, Xue Liu, Baofeng Yang, Yan Zhang

Journal: Phytomedicine

PubMed ID: 38759316

Doi: 10.1016/j.phymed.2024.155704

Products & Services: Molecular Biology Reagents

Structure-Based Virtual Screening for Methyltransferase Inhibitors of SARS-CoV-2 nsp14 and nsp16

Authors: Kejue Wu, Yinfeng Guo, Tiefeng Xu, Weifeng Huang, Deyin Guo, Liu Cao, Jinping Lei

Journal: Molecules

PubMed ID: 38792173

Doi: 10.3390/molecules29102312

Products & Services: Molecular Biology Reagents

Structure of a human monoclonal antibody in complex with Outer surface protein C (OspC) of the Lyme disease spirochete,

Authors: Michael J Rudolph, Yang Chen, Clint Vorauer, David J Vance, Carol Lyn Piazza, Graham G Willsey, Kathleen McCarthy, Beatrice Muriuki, Lisa A Cavacini, Miklos Guttman, Nicholas J Mantis

Journal: biorxiv

PubMed ID: 38746285

Doi: 10.1101/2024.04.29.591597

Products & Services: Gene Synthesis

N-MYC impairs innate immune signaling in high-grade serous ovarian carcinoma

Authors: Alex Miranda, Swetansu Pattnaik, Phineas T Hamilton, Monica Alvaro Fuss, Shreena Kalaria, Céline M Laumont, Julian Smazynski, Monica Mesa, Allyson Banville, Xinpei Jiang, Russell Jenkins, Israel Cañadas, Brad H Nelson

Journal: Sci Adv

PubMed ID: 38748789

Doi: 10.1126/sciadv.adj5428

Products & Services: Custom Vector Construction

Development of novel monoclonal antibodies for blocking NF-κB activation induced by CD2v protein in African swine fever virus

Authors: Rongrong Fan, Zeliang Wei, Mengmeng Zhang, Shanshan Jia, Zhiyang Jiang, Yao Wang, Junyu Cai, Guojiang Chen, He Xiao, Yinxiang Wei, Yanchun Shi, Jiannan Feng, Beifen Shen, Yuanqiang Zheng, Yaojiang Huang, Jing Wang

Journal: Front Immunol

PubMed ID: 38846950

Doi: 10.3389/fimmu.2024.1352404

Products & Services: Catalog Antibody

Mapping adipocyte interactome networks by HaloTag-enrichment-mass spectrometry

Authors: Junshi Yazaki, Takashi Yamanashi, Shino Nemoto, Atsuo Kobayashi, Yong-Woon Han, Tomoko Hasegawa, Akira Iwase, Masaki Ishikawa, Ryo Konno, Koshi Imami, Yusuke Kawashima, Jun Seita

Journal: Biol Methods Protoc

PubMed ID: 38884001

Doi: 10.1093/biomethods/bpae039

Products & Services: Molecular Biology Reagents

Anticancer Effects of the Trivalent Organoarsenical 2-Amino-4-(dihydroxyarsinoyl) Butanoate

Authors: Venkadesh Sarkarai Nadar, Kunie Yoshinaga-Sakurai, Barry P Rosen

Journal: Organometallics

PubMed ID: 38817537

Doi: 10.1021/acs.organomet.4c00082

Products & Services: Codon Optimization

A Novel Fluorescence-Based Microplate Assay for High-Throughput Screening of hSULT1As Inhibitors

Authors: Xiaoting Niu, Yufan Fan, Liwei Zou, Guangbo Ge

Journal: Biosensors (Basel)

PubMed ID: 38920579

Doi: 10.3390/bios14060275

Products & Services: Gene Synthesis

Structural basis for double-stranded RNA recognition by SID1

Authors: Runhao Wang, Ye Cong, Dandan Qian, Chuangye Yan, Deshun Gong

Journal: Nucleic Acids Res

PubMed ID: 38742627

Doi: 10.1093/nar/gkae395

UV-Inactivated rVSV-M2e-Based Influenza Vaccine Protected against the H1N1 Influenza Challenge

Authors: Titus Abiola Olukitibi, Zhujun Ao, Hiva Azizi, Maggie J Ouyang, Tosin Omole, Lyle McKinnon, Darwyn Kobasa, Kevin Coombs, Gary Kobinger, Xiaojian Yao

Journal: Front Biosci (Landmark Ed)

PubMed ID: 38812326

Doi: 10.31083/j.fbl2905195

Products & Services: Molecular Biology Reagents

Efficacy of a stable broadly protective subunit vaccine platform against SARS-CoV-2 variants of concern

Authors: Ravendra Garg, Qiang Liu, Jill Van Kessel, Akarin Asavajaru, Eva-Maria Uhlemann, Morgane Joessel, Glenn Hamonic, Zahed Khatooni, Andrea Kroeker, Jocelyne Lew, Erin Scruten, Paul Pennington, William Deck, Tracy Prysliak, Michaela Nickol, Falko Apel, Thomas Courant, Alyson A Kelvin, Andrew Van Kessel, Nicolas Collin, Volker Gerdts, Wolfgang Köster, Darryl Falzarano, Trina Racine, Arinjay Banerjee

Journal: Vaccine

PubMed ID: 38769033

Doi: 10.1016/j.vaccine.2024.05.028

Products & Services: Proteins, Expression, Isolation and Analysis

PARP1 interacts with WDR5 to enhance target gene recognition and facilitate tumorigenesis

Authors: Yali Qin, Xiaochuan Dong, Manman Lu, Lingyun Jing, Qingchuan Chen, Fei Guan, Zhengkai Xiang, Jiaojuan Huang, Chengxuan Yang, Ximiao He, Jing Qu, Zhenhua Yang

Journal: Cancer Lett

PubMed ID: 38750719

Doi: 10.1016/j.canlet.2024.216952

Products & Services: Proteins, Expression, Isolation and Analysis

Retinoic acid related orphan receptor α is a genetic modifier that rescues retinal degeneration in a mouse model of Stargardt disease and Dry AMD

Authors: M Akula, S M McNamee, Z Love, N Nasraty, N P M Chan, M Whalen, M O Avola, A M Olivares, B D Leehy, A S Jelcick, P Singh, A K Upadhyay, D F Chen, N B Haider

Journal: Gene Ther

PubMed ID: 38755404

Doi: 10.1038/s41434-024-00455-z

Products & Services: Catalog Antibody

A recombinant plasmid encoding human hepatocyte growth factor promotes healing of combined radiation-trauma skin injury involved in regulating Nrf2 pathway in mice

Authors: Dujuan Li, Yuxin Lu, Fengjun Xiao, Xiaochen Cheng, Chunsheng Hu, Xuefeng Zhu, Xiaoying Wang, Haiying Duan, Li Du, Qinglin Zhang

Journal: J Radiat Res

PubMed ID: 38682896

Doi: 10.1093/jrr/rrae011

Products & Services: Proteins, Expression, Isolation and Analysis

Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators

Authors: Haiyu Wang, Fleur S van de Bovenkamp, Douwe J Dijkstra, Leoni Abendstein, Nicole V Borggreven, Jos Pool, Rob Zuijderduijn, Christoph Gstöttner, Kyra A Gelderman, Timon Damelang, Gestur Vidarsson, Anna M Blom, Elena Domínguez-Vega, Paul W H I Parren, Thomas H Sharp, Leendert A Trouw

Journal: Front Immunol

PubMed ID: 38817607

Doi: 10.3389/fimmu.2024.1288597

Products & Services: Proteins, Expression, Isolation and Analysis

Long-term stability and immunogenicity of lipid nanoparticle COVID-19 mRNA vaccine is affected by particle size

Authors: Ruimeng Shi, Xueli Liu, Yajuan Wang, Meilu Pan, Shaoqin Wang, Lin Shi, Beibei Ni

Journal: Hum Vaccin Immunother

PubMed ID: 38714327

Doi: 10.1080/21645515.2024.2342592

Products & Services: Proteins, Expression, Isolation and Analysis

Transgene removal using an in cis programmed homing endonuclease via single-strand annealing in the mosquito Aedes aegypti

Authors: Keun Chae, Bryan Contreras, Joseph S Romanowski, Chanell Dawson, Kevin M Myles, Zach N Adelman

Journal: Commun Biol

PubMed ID: 38811748

Doi: 10.1038/s42003-024-06348-6

Products & Services: Gene Synthesis

A rapid and sensitive aptamer-based biosensor for beta-lactoglobulin in milk

Authors: Anqi Liu, Meng Jiang, Yuyin Wu, Han Guo, Ling Kong, Zhiwei Chen, Zhaofeng Luo

Journal: Anal Methods

PubMed ID: 38682261

Doi: 10.1039/d4ay00460d

Products & Services: Catalog Peptides

Variation in structural motifs within SARS-related coronavirus spike proteins

Authors: Francesca R Hills, Alice-Roza Eruera, James Hodgkinson-Bean, Fátima Jorge, Richard Easingwood, Simon H J Brown, James C Bouwer, Yi-Ping Li, Laura N Burga, Mihnea Bostina

Journal: PLoS Pathog

PubMed ID: 38805567

Doi: 10.1371/journal.ppat.1012158

Products & Services: Proteins, Expression, Isolation and Analysis

Structural pharmacology and therapeutic potential of 5-methoxytryptamines

Authors: Audrey L Warren, David Lankri, Michael J Cunningham, Inis C Serrano, Lyonna F Parise, Andrew C Kruegel, Priscilla Duggan, Gregory Zilberg, Michael J Capper, Vaclav Havel, Scott J Russo, Dalibor Sames, Daniel Wacker

Journal: Nature

PubMed ID: 38720072

Doi: 10.1038/s41586-024-07403-2

Products & Services: Proteins, Expression, Isolation and Analysis

Structure of the lens MP20 mediated adhesive junction

Authors: William J Nicolas, Anna Shiriaeva, Michael W Martynowycz, Angus C Grey, Yasmeen Ruma, Paul J Donaldson, Tamir Gonen

Journal: biorxiv

PubMed ID: 38798449

Doi: 10.1101/2024.05.13.594022

Products & Services: Proteins, Expression, Isolation and Analysis

Author Correction: Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors

Authors: Jody Pacalon, Guillaume Audic, Justine Magnat, Manon Philip, Jérôme Golebiowski, Christophe J Moreau, Jérémie Topin

Journal: Nat Commun

PubMed ID: 38782904

Doi: 10.1038/s41467-024-48896-9

Products & Services: Catalog Peptides

Automated optimization of the solubility of a hyper-stable α-amylase

Authors: Montader Ali, Matthew Greenig, Marc Oeller, Misha Atkinson, Xing Xu, Pietro Sormanni

Journal: Open Biol

PubMed ID: 38745462

Doi: 10.1098/rsob.240014

Products & Services: Proteins, Expression, Isolation and Analysis

Functional and biochemical characterisation of remote homologues of type IV pili proteins PilN and PilO in Helicobacter pylori

Authors: Sharmin Q Bonny, Xiaotian Zhou, Mohammad F Khan, Mohammad M Rahman, Yue Xin, Naveen Vankadari, Alexandra Tikhomirova, Jihane Homman-Ludiye, Anna Roujeinikova

Journal: IUBMB Life

PubMed ID: 38748402

Doi: 10.1002/iub.2828

Products & Services: Gene Synthesis

Leptospiral LipL45 lipoprotein undergoes processing and shares structural similarities with bacterial sigma regulators

Authors: Gabriel de Assis Noman, Bárbara Emmanuelle Lacerda de Moura, Mônica Larucci Vieira

Journal: Biochem Biophys Res Commun

PubMed ID: 38718568

Doi: 10.1016/j.bbrc.2024.150057

Products & Services: Proteins, Expression, Isolation and Analysis

Tilapia head gelatins to stabilize fish oil emulsions and the effect of extraction methods

Authors: Li Li, Guangyi Kan, Jiawei Peng, Huan Gong, Ye Zi, Cuiping Shi, Xichang Wang, Jian Zhong

Journal: Int J Biol Macromol

PubMed ID: 38734350

Doi: 10.1016/j.ijbiomac.2024.132137

Products & Services: Proteins, Expression, Isolation and Analysis

Engineering non-conventional yeast Rhodotorula toruloides for ergothioneine production

Authors: Ke Liu, Gedan Xiang, Lekai Li, Tao Liu, Jie Ke, Liangbin Xiong, Dongzhi Wei, Fengqing Wang

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 38741169

Doi: 10.1186/s13068-024-02516-2

Products & Services: Molecular Biology Reagents

Vitamin E alleviates chlorpyrifos induced glutathione depletion, lipid peroxidation and iron accumulation to inhibit ferroptosis in hepatocytes and mitigate toxicity in zebrafish

Authors: Poulami Sen Gupta, Subrata Karmakar, Ipsita Biswas, Jahnabi Ghosal, Ankur Banerjee, Soumen Roy, Deba Prasad Mandal, Shamee Bhattacharjee

Journal: Chemosphere

PubMed ID: 38735493

Doi: 10.1016/j.chemosphere.2024.142252

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Targeting Prohibitin 2-Hu-Hsp70A1A complex as a unique approach towards malaria vaccine development

Authors: Manisha Marothia, Ankita Behl, Preeti Maurya, Monika Saini, Rumaisha Shoaib, Swati Garg, Geeta Kumari, Shreeja Biswas, Akshay Munjal, Sakshi Anand, Amandeep Kaur Kahlon, Pragya Gupta, Saurav Biswas, Bidhan Goswami, Haider Thaer Abdulhameed Almuqdadi, Ipsita Pal Bhowmick, Maxim Shevtsov, Sivaprakash Ramalingam, Anand Ranganathan, Shailja Singh

Journal: iScience

PubMed ID: 38812541

Doi: 10.1016/j.isci.2024.109918

Products & Services: Codon Optimization

AAV-mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell Regeneration

Authors: Liyan Zhang, Xin Chen, Xinlin Wang, Yinyi Zhou, Yuan Fang, Xingliang Gu, Ziyu Zhang, Qiuhan Sun, Nianci Li, Lei Xu, Fangzhi Tan, Renjie Chai, Jieyu Qi

Journal: Adv Sci (Weinh)

PubMed ID: 38810137

Doi: 10.1002/advs.202304551

Products & Services: Proteins, Expression, Isolation and Analysis

Localizing Protein Expression of Transporters in Epithelial Cell Membranes of Mosquitoes

Authors: Andrea C Durant, Andrew Donini

Journal: Cold Spring Harb Protoc

PubMed ID: 37648374

Doi: 10.1101/pdb.prot108326

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Interaction between Chromodomain Y-like Protein and Androgen Receptor Signaling in Sertoli Cells Accounts for Spermatogenesis

Authors: Kuo-Chung Lan, Yin-Hua Cheng, Yun-Chiao Chang, Kuo-Ting Wei, Pei-Ling Weng, Hong-Yo Kang

Journal: Cells

PubMed ID: 38786072

Doi: 10.3390/cells13100851

Products & Services: Proteins, Expression, Isolation and Analysis

Outer membrane vesicles generated by an exogenous bacteriophage lysin and protection against Acinetobacter baumannii infection

Authors: Changchang Li, Heng Xue, Xinjing Du, Raphael Nyaruaba, Hang Yang, Hongping Wei

Journal: J Nanobiotechnology

PubMed ID: 38773507

Doi: 10.1186/s12951-024-02553-x

Products & Services: Molecular Biology Reagents

The NTE domain of PTENα/β promotes cancer progression by interacting with WDR5 via its SSSRRSS motif

Authors: Xiaolei Huang, Cheng Zhang, Xinci Shang, Yichang Chen, Qin Xiao, Zhengguo Wei, Guanghui Wang, Xuechu Zhen, Guoqiang Xu, Jinrong Min, Shaoming Shen, Yanli Liu

Journal: Cell Death Dis

PubMed ID: 38744853

Doi: 10.1038/s41419-024-06714-6

Products & Services: Proteins, Expression, Isolation and Analysis

Paraquat disrupts KIF5A-mediated axonal mitochondrial transport in midbrain neurons and its antagonism by melatonin

Authors: Huihui Hong, Jingdian Li, Tong Tong, Ting Yang, Hui Wang, Yudong Xu, Xiqin Lin, Jinxian Lin, Sicheng Liu, Kun Luo, Zhengping Yu, Wei Yuan, Huifeng Pi, Zhou Zhou

Journal: Sci Total Environ

PubMed ID: 38750743

Doi: 10.1016/j.scitotenv.2024.173119

Products & Services: Molecular Biology Reagents

Curing of a field strain of Salmonella enterica serovar Infantis isolated from poultry from its highly stable pESI like plasmid

Authors: Nadya Gruzdev, Chen Katz, Itamar Yadid

Journal: J Microbiol Methods

PubMed ID: 38782300

Doi: 10.1016/j.mimet.2024.106959

Products & Services: Codon Optimization

CaptureSelect FcXP affinity medium exhibits strong aggregate separation capability

Authors: Wanyuan Dong, Dan Zhang, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 38759705

Doi: 10.1016/j.pep.2024.106503

Products & Services: Proteins, Expression, Isolation and Analysis

COVID-19 vaccination before or during pregnancy results in high, sustained maternal neutralizing activity to SARS-CoV-2 wild-type and Delta/Omicron variants of concern, particularly following a booster dose or infection

Authors: Aniza P Mahyuddin, Hannah L F Swa, Ruifen Weng, Jingxian Zhang, Janice P Dhanaraj, Binny P Sesurajan, Mary Rauff, Pradip Dashraath, Abhiram Kanneganti, Rachel Lee, Lin-Fa Wang, Barnaby E Young, Paul A Tambyah, David C Lye, Louis Y A Chai, Sidney Yee, Mahesh Choolani, Citra N Z Mattar

Journal: Int J Infect Dis

PubMed ID: 38823622

Doi: 10.1016/j.ijid.2024.107121

Products & Services: Molecular Biology Reagents

A recombinant chimeric antigen constructed with B-cell epitopes from Mycobacterium leprae hypothetical proteins is effective for the diagnosis of leprosy

Authors: Bárbara P N Assis, Ana T Chaves, Daniela P Lage, Mariana M Cardoso, Isabela A G Pereira, Raquel S B Câmara, Camila S Freitas, Vívian T Martins, Fernanda Ludolf, Ana Laura G de Oliveira, João A Oliveira-da-Silva, Grasiele S V Tavares, Alexsandro S Galdino, Miguel A Chávez-Fumagalli, Ricardo A Machado-de-Ávila, Myron Christodoulides, Denise U Gonçalves, Lílian L Bueno, Ricardo T Fujiwara, Eduardo A F Coelho, Manoel Otávio da Costa Rocha

Journal: Diagn Microbiol Infect Dis

PubMed ID: 38718661

Doi: 10.1016/j.diagmicrobio.2024.116338

Products & Services: Recombinant Proteins

Kaposi sarcoma-associated herpesvirus complement control protein (KCP) and glycoprotein K81 are not required for viral infection or

Authors: Murali Muniraju, Lorraine Z Mutsvunguma, Ivana G Reidel, Gabriela M Escalante, Simeon Cua, Webster Musonda, Jonathan Calero-Landa, Mafalda A Farelo, Esther Rodriguez, Zhou Li, Javier Gordon Ogembo

Journal: J Virol

PubMed ID: 38767375

Doi: 10.1128/jvi.00576-24

Products & Services: Proteins, Expression, Isolation and Analysis

Effective Control of Sclerotinia Stem Rot in Canola Plants Through Application of Exogenous Hairpin RNA of Multiple Genes

Authors: Abdolbaset Azizi, Luis E Del Río Mendoza

Journal: Phytopathology

PubMed ID: 38506733

Doi: 10.1094/PHYTO-10-23-0395-KC

Products & Services: Gene Synthesis

Type IX Collagen Turnover Is Altered in Patients with Solid Tumors

Authors: Helena Port, Yi He, Morten A Karsdal, Emilie A Madsen, Anne-Christine Bay-Jensen, Nicholas Willumsen, Signe Holm Nielsen

Journal: Cancers (Basel)

PubMed ID: 38893155

Doi: 10.3390/cancers16112035

Products & Services: Catalog Antibody

Targeting Tumor Heterogeneity by Breaking a Stem Cell and Epithelial Niche Interaction Loop

Authors: Rongze Ma, Deyi Feng, Jing Chen, Jiecan Zhou, Kun Xia, Xiangyin Kong, Guohong Hu, Pengfei Lu

Journal: Adv Sci (Weinh)

PubMed ID: 38708713

Doi: doi.org/10.1002/advs.202307452

Products & Services: Gene Synthesis

PKD2 regulates autophagy and forms a protein complex with BECN1 at the primary cilium of hypothalamic neuronal cells

Authors: Camila García-Navarrete, Catalina Kretschmar, Jorge Toledo, Karla Gutiérrez, María Paz Hernández-Cáceres, Mauricio Budini, Valentina Parra, Patricia V Burgos, Sergio Lavandero, Eugenia Morselli, Daniel Peña-Oyarzún, Alfredo Criollo

Journal: Biochim Biophys Acta Mol Basis Dis

PubMed ID: 38782303

Doi: 10.1016/j.bbadis.2024.167256

Products & Services: Proteins, Expression, Isolation and Analysis

Generation and application of immortalized sheep fetal fibroblast cell line

Authors: Guoyu Du, Cheng Zhang, Xiaoan Cao, Lingxia Li, Yong Zhang, Youjun Shang, Jinyan Wu

Journal: BMC Vet Res

PubMed ID: 38745180

Doi: 10.1186/s12917-024-04054-3

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Mucosal vaccination in a murine gnotobiotic model of infection

Authors: Sozaburo Ihara, Brian V Nguyen, Yukiko Miyamoto, Lars Eckmann

Journal: Infect Immun

PubMed ID: 38722167

Doi: 10.1128/iai.00065-24

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The investigation of the role of oral-originated induced inflammation in childhood asthma

Authors: Tongtong Yan, Yuling Bao, Shuyuan Cao, Ping Jiang, Zhan Zhang, Lei Li, Yulin Kang, Qian Wu

Journal: Front Microbiol

PubMed ID: 38863747

Doi: 10.3389/fmicb.2024.1400079

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Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6

Authors: Kaito A Nagashima, John V Dzimianski, Meng Yang, Jan Abendroth, Giuseppe A Sautto, Ted M Ross, Rebecca M DuBois, Thomas E Edwards, Jarrod J Mousa

Journal: Structure

PubMed ID: 38810648

Doi: 10.1016/j.str.2024.05.001

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Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein

Authors: Johannes P M Langedijk, Freek Cox, Nicole V Johnson, Daan van Overveld, Lam Le, Ward van den Hoogen, Richard Voorzaat, Roland Zahn, Leslie van der Fits, Jarek Juraszek, Jason S McLellan, Mark J G Bakkers

Journal: Nat Commun

PubMed ID: 38821950

Doi: 10.1038/s41467-024-48059-w

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Whole-cell one-pot biosynthesis of dodecanedioic acid from renewable linoleic acid

Authors: Yi-Ke Qi, Jiang Pan, Zhi-Jun Zhang, Jian-He Xu

Journal: Bioresour Bioprocess

PubMed ID: 38780695

Doi: 10.1186/s40643-024-00770-8

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Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM

Authors: Emil Gustavsson, Kay Grünewald, Per Elias, B Martin Hällberg

Journal: Nucleic Acids Res

PubMed ID: 38806233

Doi: 10.1093/nar/gkae374

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Rational design and production of a chimeric antigen targeting Zika virus that induces neutralizing antibodies in mice

Authors: Arleth Miranda-López, Omar González-Ortega, Dania O Govea-Alonso, Lourdes Betancourt-Mendiola, Mauricio Comas-García, Sergio Rosales-Mendoza

Journal: Vaccine

PubMed ID: 38749821

Doi: 10.1016/j.vaccine.2024.04.080

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Engineered coiled-coil HIF1α protein domain mimic

Authors: Dustin Britton, Olga Katsara, Orin Mishkit, Andrew Wang, Neelam Pandya, Chengliang Liu, Heather Mao, Jakub Legocki, Sihan Jia, Yingxin Xiao, Orlando Aristizabal, Deven Paul, Yan Deng, Robert Schneider, Youssef Z Wadghiri, Jin Kim Montclare

Journal: Biomater Sci

PubMed ID: 38656316

Doi: 10.1039/d4bm00354c

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CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition

Authors: Ali M Nasser, Lisa Melamed, Ethan Wetzel, Chia-Chen Chang, Hiroaki Nagashima, Yosuke Kitagawa, Logan Muzyka, Hiroaki Wakimoto, Daniel P Cahill, Julie J Miller

Journal: Clin Cancer Res

PubMed ID: 38718141

Doi: 10.1158/1078-0432.CCR-24-0562

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Glycosyl transferase GT2 genes mediate the biosynthesis of an unusual (1,3;1,4)-β-glucan exopolysaccharide in the bacterium Sarcina ventriculi

Authors: Edwin R Lampugnani, Kris Ford, Yin Ying Ho, Allison van de Meene, Jelle Lahnstein, Hwei-Ting Tan, Rachel A Burton, Geoffrey B Fincher, Thomas Shafee, Antony Bacic, Jochen Zimmer, Xiaohui Xing, Vincent Bulone, Monika S Doblin, Eric M Roberts

Journal: Mol Microbiol

PubMed ID: 38750617

Doi: 10.1111/mmi.15276

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Biochemical synthesis of taxanes from mevalonate

Authors: Jing Li, Xiaonan Liu, Xiaoxi Zhu, Jiayu Liu, Lei Zhang, Nida Ahmed, Jian Qi, Bihuan Chen, Daliang Tang, Jinsheng Yu, Zhijin Fan, Huifeng Jiang

Journal: Synth Syst Biotechnol

PubMed ID: 38868609

Doi: 10.1016/j.synbio.2024.05.002

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Dimerization and antidepressant recognition at noradrenaline transporter

Authors: Heng Zhang # 1, Yu-Ling Yin # 2, Antao Dai # 3 4, Tianwei Zhang 2 5, Chao Zhang 4 6, Canrong Wu 1, Wen Hu 1 7, Xinheng He 1 8, Benxun Pan 2, Sanshan Jin 2, Qingning Yuan 1 7, Ming-Wei Wang 9 10 11, Dehua Yang 12 13 14, H Eric Xu 15 16 17, Yi Jiang 18 19

Journal: Nature

PubMed ID: 38750358

Doi: 10.1038/s41586-024-07437-6.

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Biochemical characterization of a novel thermostable ulvan lyase from Tamlana fucoidanivorans CW2-9

Authors: Yan Xu, Jin Li, Lu An, Yuankai Qiu, Aihua Mao, Zhixiao He, Jialing Guo, Hanbing Yan, Han Li, Zhong Hu

Journal: J Agric Food Chem

PubMed ID: 38722333

Doi: 10.1021/acs.jafc.4c01717

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Exploring roles of the chitinase ChiC in modulating virulence phenotypes

Authors: Per Kristian Thorén Edvardsen, Fatemeh Askarian, Raymond Zurich, Victor Nizet, Gustav Vaaje-Kolstad

Journal: Microbiol Spectr

PubMed ID: 38819151

Doi: 10.1128/spectrum.00546-24

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Tumor-repopulating cells evade ferroptosis via PCK2-dependent phospholipid remodeling

Authors: Zhe Li, Zhi-Min Xu, Wei-Peng Chen, Xiao-Jing Du, Chun-Xian Ou, Zi-Kang Luo, Rong Wang, Chu-Qing Zhang, Chao-Dong Ge, Meng Han, Fudi Wang, Rong-Rong He, Wan-Yang Sun, Jun Ma, Xiao-Yu Liang, Zhuo-Wei Liu

Journal: Nat Chem Biol

PubMed ID: 38720107

Doi: 10.1038/s41589-024-01612-6

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Targeted Clearance of Senescent Cells Via Engineered Extracellular Vesicles Reprograms Tumor Immunosuppressive Microenvironment

Authors: Panpan Ji, Chen Wang, Yang Liu, Xin Guo, Yuan Liang, Jiangpeng Wei, Zhaoyou Liu, Li Gong, Guodong Yang, Gang Ji

Journal: Adv Healthc Mater

PubMed ID: 38794820

Doi: 10.1002/adhm.202400945

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Improvement of tumor neoantigen detection by high field asymmetric waveform ion mobility mass spectrometry

Authors: Wei Meng, Yoshiko Takeuchi, Jeffrey P Ward, Hussein Sultan, Cora D Arthur, Elaine R Mardis, Maxim N Artyomov, Cheryl F Lichti, Robert D Schreiber

Journal: Cancer Immunol Res

PubMed ID: 38768391

Doi: 10.1158/2326-6066.CIR-23-0900

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Proteomic and lipidomic landscape of the infrapatellar fat pad and its clinical significance in knee osteoarthritis

Authors: Bizhi Tu, Zheng Zhu, Peizhi Lu, Run Fang, Cheng Peng, Jun Tong, Rende Ning

Journal: Biochim Biophys Acta Mol Cell Biol Lipids

PubMed ID: 38788831

Doi: 10.1016/j.bbalip.2024.159513

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Structural Insights into Subunit-Dependent Functional Regulation in Epithelial Sodium Channels

Authors: Alexandra Houser, Isabelle Baconguis

Journal: biorxiv

PubMed ID: 38853903

Doi: 10.1101/2024.05.28.595834

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Evaluating the clinical utility of semi-quantitative luciferase immunosorbent assay using antigens in syphilis diagnosis and treatment monitoring

Authors: Wujian Ke, Cailing Ao, Ran Wei, Xiaozhen Zhu, Jingwei Shui, Jianhui Zhao, Xiaohui Zhang, Liuyuan Wang, Liping Huang, Xinying Leng, Rui Zhu, Jiaxin Wu, Lixia Huang, Nanxuan Huang, Haiying Wang, Wenjia Weng, Ligang Yang, Shixing Tang

Journal: Emerg Microbes Infect

PubMed ID: 38661428

Doi: 10.1080/22221751.2024.2348525

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Design and Evaluation of a Humanized Anti-EGFR huscFv Antibody Fragment in Combination With Metformin in A549 Cells

Authors: Jorge Solis-Estrada, Eder Arredondo-Espinoza, Elizeth Pioquinto-Ávila, Aldo O González-Cruz, Xristo Zarate, Isaías Balderas-Rentería

Journal: Anticancer Res

PubMed ID: 38677771

Doi: 10.21873/anticanres.16998

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Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones

Authors: Jennifer A Smith, Benjamin T K Yuen, Whitney Purtha, Jared M Balolong, Jonah D Phipps, Frances Crawford, Jeffrey A Bluestone, John W Kappler, Mark S Anderson

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38709934

Doi: 10.1073/pnas.2320268121

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Optimizing interleukin-6 and 8 expression, clarification and purification in plant cell packs and plants for application in advanced therapy medicinal products and cellular agriculture

Authors: P Opdensteinen, J F Buyel

Journal: J Biotechnol

PubMed ID: 38740307

Doi: 10.1016/j.jbiotec.2024.05.003

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HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington's disease mice

Authors: Laiqiang Chen, Yiyang Qin, Tingting Guo, Wenzhen Zhu, Jingpan Lin, Tingting Xing, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Xiang Li, Peng Yin, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: Cell Death Dis

PubMed ID: 38744826

Doi: 10.1038/s41419-024-06716-4

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Evolved histone tail regulates 53BP1 recruitment at damaged chromatin

Authors: Jessica L Kelliher, Melissa L Folkerts, Kaiyuan V Shen, Wan Song, Kyle Tengler, Clara M Stiefel, Seong-Ok Lee, Eloise Dray, Weixing Zhao, Brian Koss, Nicholas R Pannunzio, Justin W Leung

Journal: Nat Commun

PubMed ID: 38821984

Doi: 10.1038/s41467-024-49071-w

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A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction

Authors: Baiyang Sun, Zihe Liang, Yupeng Wang, Yue Yu, Xiaobing Zhou, Xingchao Geng, Bo Li

Journal: Toxicology

PubMed ID: 38740170

Doi: 10.1016/j.tox.2024.153829

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Development of a Fully Protective Pandemic Avian Influenza Subunit Vaccine in Insect Pupae

Authors: Ana Falcón, Susana Martínez-Pulgarín, Sergi López-Serrano, Edel Reytor, Miguel Cid, Maria Del Carmen Nuñez, Lorena Córdoba, Ayub Darji, José M Escribano

Journal: Viruses

PubMed ID: 38932122

Doi: 10.3390/v16060829

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Structural mechanisms of Tad pilus assembly and its interaction with an RNA virus

Authors: Yuhang Wang, Matthew Theodore, Zhongliang Xing, Utkarsh Narsaria, Zihao Yu, Lanying Zeng, Junjie Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 38701202

Doi: 10.1126/sciadv.adl4450

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TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington’s disease

Authors: Yiyang Qin, Laiqiang Chen, Wenzhen Zhu, Jiahong Song, Jingpan Lin, Yuwei Li, Jiawei Zhang, Xichen Song, Tingting Xing, Tingting Guo, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Qi Wang, Bang Li, Weili Yang , Peng Yin, Xiao-Xin Yan, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: SCIENCE ADVANCES

PubMed ID: 38758800

Doi: 10.1126/sciadv.adl2036

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In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model

Authors: Melisa Benard-Valle, Yessica Wouters, Anne Ljungars, Giang Thi Tuyet Nguyen, Shirin Ahmadi, Tasja Wainani Ebersole, Camilla Holst Dahl, Alid Guadarrama-Martínez, Frederikke Jeppesen, Helena Eriksen, Gibran Rodríguez-Barrera, Kim Boddum, Timothy Patrick Jenkins, Sara Petersen Bjørn, Sanne Schoffelen, Bjørn Gunnar Voldborg, Alejandro Alagón & Andreas Hougaard Laustsen

Journal: Nat Commun

PubMed ID: 38773068

Doi: 10.1038/s41467-024-48539-z

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Dendritic-cell-targeting virus-like particles as potent mRNA vaccine carriers

Authors: Di Yin # 1, Yiye Zhong # 1, Sikai Ling # 1 2, Sicong Lu # 1, Xiaoyuan Wang # 2, Zhuofan Jiang 1, Jie Wang 1, Yao Dai 1, Xiaolong Tian 3, Qijing Huang 1, Xingbo Wang 4, Junsong Chen 1, Ziying Li 1, Yang Li 1, Zhijue Xu 1, Hewei Jiang 1, Yuqing Wu 5, Yi Shi 6, Quanjun Wang 7, Jianjiang Xu 5, Wei Hong 8 9, Heng Xue 8 9, Hang Yang 8 9 10, Yan Zhang 1, Lintai Da 1, Ze-Guang Han 1, Sheng-Ce Tao 1, Ruijiao Dong 1, Tianlei Ying 3, Jiaxu Hong 11, Yujia Cai 12

Journal: Nat Biomed Eng

PubMed ID: 38714892

Doi: 10.1038/s41551-024-01208-4

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Impact of N-Glycosylation on Protein Structure and Dynamics Linked to Enzymatic C–H Activation in the M. oryzae Lipoxygenase

Authors: Chris Whittington, Ajay Sharma, S Gage Hill, Anthony T Iavarone, Brian M Hoffman, Adam R Offenbacher

Journal: Biochemistry

PubMed ID: 38690768

Doi: 10.1021/acs.biochem.4c00109

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Manganese-dependent transcription regulation by MntR and PerR in Thermus thermophilus HB8

Authors: John K Barrows, Kamya A Stubbs, Irina F Padilla-Montoya, Thomas C Leeper, Michael W Van Dyke

Journal: Mol Microbiol

PubMed ID: 38735869

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Delineating organizational principles of the endogenous L-A virus by cryo-EM and computational analysis of native cell extracts

Authors: Lisa Schmidt, Christian Tüting, Fotis L Kyrilis, Farzad Hamdi, Dmitry A Semchonok, Gerd Hause, Annette Meister, Christian Ihling, Milton T Stubbs, Andrea Sinz, Panagiotis L Kastritis

Journal: Commun Biol

PubMed ID: 38730276

Doi: 10.1038/s42003-024-06204-7

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Combinatorial Metabolic Engineering for Improving Betulinic Acid Biosynthesis in

Authors: Mei Tang, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu

Journal: ACS Synth Biol

PubMed ID: 38748665

Doi: 10.1021/acssynbio.4c00104

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and gene-edited human induced pluripotent stem cells for dissecting the functional roles of -GlcNAcylation in hematopoiesis

Authors: Sudjit Luanpitpong, Kantpitchar Tangkiettrakul, Xing Kang, Pimonwan Srisook, Jirarat Poohadsuan, Parinya Samart, Phatchanat Klaihmon, Montira Janan, Chanchao Lorthongpanich, Chuti Laowtammathron, Surapol Issaragrisil

Journal: Front Cell Dev Biol

PubMed ID: 38752196

Doi: 10.3389/fcell.2024.1361943

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Integrating cryo-OrbiSIMS with computational modelling and metadynamics simulations enhances RNA structure prediction at atomic resolution

Authors: Shannon Ward, Alex Childs, Ceri Staley, Christopher Waugh, Julie A Watts, Anna M Kotowska, Rahul Bhosale, Aditi N Borkar

Journal: Nat Commun

PubMed ID: 38777820

Doi: 10.1038/s41467-024-48694-3

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