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PACER: a novel 3D plant cell wall model for the analysis of non-catalytic and enzymatic responses

Authors: Mareike Monschein, Edita Jurak, Tanja Paasela, Taru Koitto, Vera Lambauer, Mirko Pavicic, Thomas Enjalbert, Claire Dumon, Emma R Master

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 35296345

Doi: 10.1186/s13068-022-02128-8

Products & Services: Proteins, Expression, Isolation and Analysis

Large-scale design and refinement of stable proteins using sequence-only models

Authors: Jedediah M Singer, Scott Novotney, Devin Strickland, Hugh K Haddox, Nicholas Leiby, Gabriel J Rocklin, Cameron M Chow, Anindya Roy, Asim K Bera, Francis C Motta, Longxing Cao, Eva-Maria Strauch, Tamuka M Chidyausiku, Alex Ford, Ethan Ho, Alexander Zaitzeff, Craig O Mackenzie, Hamed Eramian, Frank DiMaio, Gevorg Grigoryan, Matthew Vaughn, Lance J Stewart, David Baker, Eric Klavins

Journal: PLoS ONE

PubMed ID: 35286324

Doi: 10.1371/journal.pone.0265020

Products & Services: Plasmid DNA Preparation

Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

Authors: Jeroen Pollet, Ulrich Strych, Wen-Hsiang Chen, Leroy Versteeg, Brian Keegan, Bin Zhan, Junfei Wei, Zhuyun Liu, Jungsoon Lee, Rakhi Kundu, Rakesh Adhikari, Cristina Poveda, Maria Jose Villar, Syamala Rani Thimmiraju, Brianna Lopez, Portia M Gillespie, Shannon Ronca, Jason T Kimata, Martin Reers, Vikram Paradkar, Peter Hotez, Maria Elena Bottazzi

Journal: biorxiv

PubMed ID: 34268512

Doi: 10.1101/2021.07.06.451353

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UBR4/POE facilitates secretory trafficking to maintain circadian clock synchrony

Authors: Sara Hegazi, Arthur H Cheng, Joshua J Krupp, Takafumi Tasaki, Jiashu Liu, Daniel A Szulc, Harrod H Ling, Julian Rios Garcia, Shavanie Seecharran, Tayebeh Basiri, Mehdi Amiri, Zobia Anwar, Safa Ahmad, Kamar Nayal, Nahum Sonenberg, Bao-Hua Liu, Hai-Ling Margaret Cheng, Joel D Levine, Hai-Ying Mary Cheng

Journal: Nat Commun

PubMed ID: 35332162

Doi: 10.1038/s41467-022-29244-1

Products & Services: GenParts™ DNA Fragments

A "spindle and thread" mechanism unblocks p53 translation by modulating N-terminal disorder

Authors: Margit Kaldmäe, Thibault Vosselman, Xueying Zhong, Dilraj Lama, Gefei Chen, Mihkel Saluri, Nina Kronqvist, Jia Wei Siau, Aik Seng Ng, Farid J Ghadessy, Pierre Sabatier, Borivoj Vojtesek, Médoune Sarr, Cagla Sahin, Nicklas Österlund, Leopold L Ilag, Venla A Väänänen, Saikiran Sedimbi, Marie Arsenian-Henriksson, Roman A Zubarev, Lennart Nilsson, Philip J B Koeck, Anna Rising, Axel Abelein, Nicolas Fritz, Jan Johansson, David P Lane, Michael Landreh

Journal: Structure

PubMed ID: 35290795

Doi: 10.1016/j.str.2022.02.013

Products & Services: Proteins, Expression, Isolation and Analysis

Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody

Authors: Cheng Li, Wuqiang Zhan, Zhenlin Yang, Chao Tu, Gaowei Hu, Xiang Zhang, Wenping Song, Shujuan Du, Yuanfei Zhu, Keke Huang, Yu Kong, Meng Zhang, Qiyu Mao, Xiaodan Gu, Yi Zhang, Youhua Xie, Qiang Deng, Yuanlin Song, Zhenguo Chen, Lu Lu, Shibo Jiang, Yanling Wu, Lei Sun, Tianlei Ying

Journal: Cell

PubMed ID: 35344711

Doi: 10.1016/j.cell.2022.03.009

Products & Services: PCR Cloning and Subcloning

Ramifications of the HLA-I Allelic Reactivity of Anti-HLA-E*01:01 and Anti-HLA-E*01:03 Heavy Chain Monoclonal Antibodies in Comparison with Anti-HLA-I IgG Reactivity in Non-Alloimmunized Males, Melanoma-Vaccine Recipients, and End-Stage Renal Disease Patients

Authors: Mepur H Ravindranath, Narendranath M Ravindranath, Fatiha El Hilali, Senthamil R Selvan, Edward J Filippone

Journal: Antibodies (Basel)

PubMed ID: 35323192

Doi: 10.3390/antib11010018

Products & Services: Proteins, Expression, Isolation and Analysis

Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling

Authors: Maricel Gomez-Soler, Marina P. Gehring, Bernhard C. Lechtenberg,Elmer Zapata-Mercado, Alyssa Ruelos,Mike W. Matsumoto,Kalina Hristova,and Elena B. Pasquale

Journal: iScience

Doi: doi.org/10.1016/j.isci.2022.103870

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Global profiling of regulatory elements in the histone benzoylation pathway

Authors: Duo Wang , Fuxiang Yan , Ping Wu, Kexue Ge , Muchun Li , Tingting Li , Ying Gao , Chao Peng , Yong Chen

Journal: Nat Commun

PubMed ID: 35296687

Doi: 10.1038/s41467-022-29057-2

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A multifunctional enolase mediates cytoadhesion and interaction with host plasminogen and fibronectin in Mycoplasma hyorhinis

Authors: Jia Wang , Yanfei Yu , Yao Li , Shiyang Li , Li Wang , Yanna Wei , Yuzi Wu , Bala Pillay , Ademola Olufolahan Olaniran , Thamsanqa E Chiliza , Guoqing Shao , Zhixin Feng , Qiyan Xiong

Journal: Vet Res

PubMed ID: 35337383

Doi: 10.1186/s13567-022-01041-0

Products & Services: Gene Synthesis Recombinant Antibody Expression

Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression

Authors: Yvonne E Smith, Guannan Wang, Ciara L Flynn, Stephen F Madden, Owen MacEneaney, Rodrigo G B Cruz, Cathy E Richards, Hanne Jahns, Marian Brennan, Mattia Cremona, Bryan T Hennessy, Katherine Sheehan, Alexander Casucci, Faizah A Sani, Lance Hudson, Joanna Fay, Sri H Vellanki, Siobhan O'Flaherty, Marc Devocelle, Arnold D K Hill, Kieran Brennan, Saraswati Sukumar, Ann M Hopkins

Journal: Cancers (Basel)

PubMed ID: 35267611

Doi: 10.3390/cancers14051303

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A Protein vaccine with Alum/c-GAMP/poly(I:C) rapidly boosts robust immunity against SARS-CoV-2 and variants of concern

Authors: Ru-Yan Zhang , Xu-Guang Yin , Shi-Hao Zhou , Hai-Wei Zhang , Jie Lu , Chen-Bin He , Jian Wang , Yu Wen , Yu-Ting Li , Yan-Ling Liu , Ran-Ran Feng , Dong Ding , Hua-Wei Wei , Rui Gong , Guang-Fu Yang , Jun Guo

Journal: Chem Commun

PubMed ID: 35244125

Doi: 10.1039/D2CC00271J

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Gene therapy for guanidinoacetate methyltransferase deficiency restores cerebral and myocardial creatine while resolving behavioral abnormalities

Authors: Suhail Khoja, Jenna Lambert, Matthew Nitzahn, Adam Eliav, YuChen Zhang, Mikayla Tamboline, Colleen T Le, Eram Nasser, Yunfeng Li, Puja Patel, Irina Zhuravka, Lindsay M Lueptow, Ilona Tkachyova, Shili Xu, Itzhak Nissim, Andreas Schulze, Gerald S Lipshutz

Journal: Mol Ther Methods Clin Dev

PubMed ID: 35505663

Doi: 10.1016/j.omtm.2022.03.015

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Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules

Authors: Hui Jin, Kazuki Kishida, Noriko Arase, Sumiko Matsuoka, Wataru Nakai, Masako Kohyama, Tadahiro Suenaga, Ken Yamamoto, Takehiko Sasazuki, Hisashi Arase

Journal: Sci Adv

PubMed ID: 35245125

Doi: 10.1126/sciadv.abj9867

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The interaction of dengue virus capsid protein with negatively charged interfaces drives the in vitro assembly of nucleocapsid-like particles

Authors: Nathane C Mebus-Antunes, Wellington S Ferreira, Glauce M Barbosa, Thais C Neves-Martins, Gilberto Weissmuller, Fabio C L Almeida, Andrea T Da Poian

Journal: PLoS ONE

PubMed ID: 35231063

Doi: 10.1371/journal.pone.0264643

Products & Services: Proteins, Expression, Isolation and Analysis

Modular engineering of coculture for efficient production of resveratrol from glucose and arabinose mixture

Authors: Jia Li, Zetian Qiu, Guang-Rong Zhao

Journal: Synth Syst Biotechnol

PubMed ID: 35330959

Doi: 10.1016/j.synbio.2022.03.001

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Mobility of FLOWERING LOCUS T protein as a systemic signal in trifoliate orange and its low accumulation in grafted juvenile scions

Authors: Yan-Mei Wu, Yu-Jiao Ma, Min Wang, Huan Zhou, Zhi-Meng Gan, Ren-Fang Zeng, Li-Xia Ye, Jing-Jing Zhou, Jin-Zhi Zhang, Chun-Gen Hu

Journal: Hortic Res

PubMed ID: 35702366

Doi: 10.1093/hr/uhac056

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Expression in Wilms Tumor Is Regulated by Promoter Mutation or Hypermethylation, WT1, and N-MYC

Authors: Carolyn M Jablonowski, Hyea Jin Gil, Emilia M Pinto, Prahalathan Pichavaram, Andrew M Fleming, Michael R Clay, Dongli Hu, Christopher L Morton, Shondra M Pruett-Miller, Baranda S Hansen, Xiang Chen, Karissa M Dieseldorff Jones, Yanling Liu, Xiaotu Ma, Jun Yang, Andrew M Davidoff, Gerard P Zambetti, Andrew J Murphy

Journal: Cancers (Basel)

PubMed ID: 35406427

Doi: 10.3390/cancers14071655

Products & Services: Gene Synthesis

SLiM Ligand Mimetic Activates Notch Signaling in Human Monocytes

Authors: LaNisha L Patterson, Thangam Sudha Velayutham, Caitlan D Byerly, Duc Cuong Bui, Jignesh Patel, Veljko Veljkovic, Slobodan Paessler, Jere W McBride

Journal: MBio

PubMed ID: 35357214

Doi: 10.1128/mbio.00076-22

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Mouse Adenovirus Type 1 E4orf6 Induces PKR Degradation

Authors: Berto Tejera-Hernández, Danielle E Goodman, Juan M Nevarez, Katherine R Spindler

Journal: J Virol

PubMed ID: 35285681

Doi: 10.1128/jvi.02063-21

Products & Services: Plasmid DNA Preparation

Metabolic engineering of Saccharomyces cerevisiae for gram-scale diosgenin production

Authors: Liping Xu , Dong Wang , Jing Chen , Bo Li , Qingyan Li , Pingping Liu , Ying Qin , Zhubo Dai , Feiyu Fan , Xueli Zhang

Journal: Metab Eng

PubMed ID: 35085779

Doi: 10.1016/j.ymben.2022.01.013

Products & Services: Codon Optimization

A compact and simple method of achieving differential transgene expression by exploiting translational readthrough

Authors: James E Sillibourne, Giulia Agliardi, Matteo Righi, Katerina Smetanova, Grant Rowley, Simon Speller, Abigail Dolor, Katarina Lamb, Christopher Allen, Rajeev Karattil, Farhaan Parekh, Frederick Arce Vargas, Simon Thomas, Shaun Cordoba, Martin Pule

Journal: BioTechniques

PubMed ID: 35234525

Doi: 10.2144/btn-2021-0079

Products & Services: Mammalian Expression

Distinct effects of treatment with two different interferon-alpha subtypes on HIV-1-associated T-cell activation and dysfunction in humanized mice

Authors: Saurav S Rout, Yunyun Di, Ulf Dittmer, Kathrin Sutter, Kerry J Lavender

Journal: AIDS

PubMed ID: 35084382

Doi: 10.1097/QAD.0000000000003111

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Porcine circovirus 4 rescued from an infectious clone is replicable and pathogenic in vivo

Authors: Guyu Niu, Xinwei Zhang, Weilong Ji, Si Chen, Xue Li, Lin Yang, Liying Zhang, Hongsheng Ouyang, Chang Li, Linzhu Ren

Journal: Transbound Emerg Dis

PubMed ID: 35240007

Doi: 10.1111/tbed.14498

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Targeting an evolutionarily conserved "E-L-L" motif in the spike protein to develop a small molecule fusion inhibitor against SARS-CoV-2

Authors: Indrani Das Jana, Prabuddha Bhttacharya, Karthick Mayilsamy, Saptarshi Banerjee, Gourab Bhattacharje, Sayan Das, Seemanti Aditya, Anandita Ghosh, Andrew R McGill, Syamanthak Srikrishnan, Amit Kumar Das, Amit Basak, Shyam S Mohapatra, Bala Chandran, Devesh Bhimsaria, Subhra Mohapatra, Arunava Roy, Arindam Mondal

Journal: biorxiv

PubMed ID: 35313575

Doi: 10.1101/2022.03.16.484554

Products & Services: Proteins, Expression, Isolation and Analysis

OsASHL1 and OsASHL2, two members of the COMPASS-like complex, control floral transition and plant development in rice

Authors: Guangxin Zhao, Jingying Wang, Xi Chen, Hanjing Sha, Xin Liu, Yunfei Han, Guankai Qiu, Fantao Zhang, Jun Fang

Journal: J Genet Genomics

PubMed ID: 35306222

Doi: 10.1016/j.jgg.2022.02.026

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Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies

Authors: Anusmita Sahoo, Edgar A Hodge, Celia C LaBranche, Tiffany M Styles, Xiaoying Shen, Narayanaiah Cheedarla, Ayalnesh Shiferaw, Gabriel Ozorowski, Wen-Hsin Lee, Andrew B Ward, Georgia D Tomaras, David C Montefiori, Darrell J Irvine, Kelly K Lee, Rama Rao Amara

Journal: Cell Rep

PubMed ID: 35235790

Doi: 10.1016/j.celrep.2022.110436

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Study of osmoadaptation mechanisms of halophilic Halomonas alkaliphila XH26 under salt stress by transcriptome and ectoine analysis

Authors: Tiantian Zhang, Xin Zhang, Yongzhen Li, Ning Yang, Lijuan Qiao, Zengqiang Miao, Jiangwa Xing, Derui Zhu

Journal: Extremophiles

PubMed ID: 35229247

Doi: 10.1007/s00792-022-01256-1

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Targeting insulin-like growth factor-1 receptor (IGF1R) for brain delivery of biologics

Authors: Wael Alata, Alvaro Yogi, Eric Brunette, Christie E Delaney, Henk van Faassen, Greg Hussack, Umar Iqbal, Kristin Kemmerich, Arsalan S Haqqani, Maria J Moreno, Danica B Stanimirovic

Journal: FASEB J

PubMed ID: 35192204

Doi: 10.1096/fj.202101644R

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ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve

Authors: Hye-Jin Park, Eric Tsai, Dennis Huang, Michael Weaver, Luciana Frick, Ace Alcantara, John J Moran, Julia Patzig, Carmen V Melendez-Vasquez, Gerald R Crabtree, M L Feltri, John Svaren, Patrizia Casaccia

Journal: iScience

PubMed ID: 35434551

Doi: 10.1016/j.isci.2022.104132

Products & Services: Proteins, Expression, Isolation and Analysis

Undiagnosed COVID-19 in households with a child with mitochondrial disease

Authors: Eliza M Gordon-Lipkin, Christopher Marcum, Shannon Kruk, Elizabeth Thompson, Sophie E M Kelly, Heather Kalish, Kaitlyn Sadtler, Peter J McGuire

Journal: medrxiv

PubMed ID: 35350208

Doi: 10.1101/2022.03.21.22272358

Products & Services: Recombinant Antibody Expression

MdMTA-mediated m A modification enhances drought tolerance by promoting mRNA stability and translation efficiency of genes involved in lignin deposition and oxidative stress

Authors: Nan Hou, Chaoshuo Li, Jieqiang He, Yu Liu, Sisi Yu, Mickael Malnoy, Muhammad Mobeen Tahir, Lingfei Xu, Fengwang Ma, Qingmei Guan

Journal: New Phytol

PubMed ID: 35246985

Doi: 10.1111/nph.18069

Products & Services: Proteins, Expression, Isolation and Analysis

PINK1/Parkin-mediated mitophagy is activated to protect against AFB-induced kidney damage in mice

Authors: Yuping Wang, Miao Song, Qi Wang, Chen Guo, Jian Zhang, Xuliang Zhang, Yilong Cui, Zheng Cao, Yanfei Li

Journal: Chem Biol Interact

PubMed ID: 35304092

Doi: 10.1016/j.cbi.2022.109884

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A randomized clinical trial of a booster dose with low versus standard dose of AZD1222 in adult after 2 doses of inactivated vaccines

Authors: Sira Nanthapisal, Thanyawee Puthanakit, Peera Jaru-Ampornpan, Rapisa Nantanee, Pimpayao Sodsai, Orawan Himananto, Jiratchaya Sophonphan, Pintip Suchartlikitwong, Narin Hiransuthikul, Pornpimon Angkasekwinai, Auchara Tangsathapornpong, Nattiya Hirankarn

Journal: Vaccine

PubMed ID: 35341647

Doi: 10.1016/j.vaccine.2022.03.036

Products & Services: Mammalian Expression

Overexpression of microRNA-107 suppressed proliferation, migration, invasion, and the PI3K/Akt signaling pathway and induced apoptosis by targeting Nin one binding (NOB1) protein in a hypopharyngeal squamous cell carcinoma cell line (FaDu)

Authors: Xin Gao, Xinlong Fan, Wei Zeng, Jiwang Liang, Nan Guo, Xiao Yang, Yuejiao Zhao

Journal: Bioengineered

PubMed ID: 35294329

Doi: 10.1080/21655979.2022.2051266

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Simultaneous Detection of Bladder Cancer Exosomal MicroRNAs Based on Inorganic Nanoflare and DNAzyme Walker

Authors: Xiao Zhang, Xiaowei Wei, Jijin Qi, Jie Shen, Junwen Xu, Guangyu Gong, Yong Wei, Jian Yang, Qingyi Zhu, Tingting Bai, Zhirui Guo, Xiaojun Qu, Yefei Zhu

Journal: Anal Chem

PubMed ID: 35275615

Doi: 10.1021/acs.analchem.1c05588

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Characterization of Bud3 domains sufficient for bud neck targeting in

Authors: Madison N Schrock, Yao Yan, Megan E Goeckel, Erianna M Basgall, Isabel C Lewis, Katherine G Leonard, Megan Halloran, Gregory C Finnigan

Journal: Access Microbiol

PubMed ID: 35693471

Doi: 10.1099/acmi.0.000341

Products & Services: Proteins, Expression, Isolation and Analysis

Comparative performance of five recombinant and chimeric antigens in a time-resolved fluorescence immunoassay for detection of Toxoplasma gondii infection in cats

Authors: Ana Huertas-López, Marinela Contreras Rojo, Woraporn Sukhumavasi, Silvia Martínez-Subiela, Gema Álvarez-García, Nadia María López-Ureña, José Joaquín Cerón, Carlos Martínez-Carrasco

Journal: Vet Parasitol

PubMed ID: 35367904

Doi: 10.1016/j.vetpar.2022.109703

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The evolutionarily conserved arginyltransferase 1 mediates a pVHL-independent oxygen-sensing pathway in mammalian cells

Authors: Balaji T Moorthy, Chunhua Jiang, Devang M Patel, Yuguang Ban, Corin R O'Shea, Akhilesh Kumar, Tan Yuan, Michael D Birnbaum, Aldrin V Gomes, Xi Chen, Flavia Fontanesi, Theodore J Lampidis, Antoni Barrientos, Fangliang Zhang

Journal: Dev Cell

PubMed ID: 35247316

Doi: 10.1016/j.devcel.2022.02.010

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A toolkit for recombinant production of seven human EGF family growth factors in active conformation

Authors: Arthur Schveitzer Ferreira, Amanda Lopacinski, Michel Batista, Priscila Mazzocchi Hiraiwa, Beatriz Gomes Guimarães, Nilson Ivo Tonin Zanchin

Journal: Sci Rep

PubMed ID: 35322149

Doi: 10.1038/s41598-022-09060-9

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Expression of B subtilis Phytase gene driven by fruit specific E8 promoter for enhanced minerals, metabolites and phytonutrient in cucumber fruit

Authors: Komal K Sapara, Parinita Agarwal, Kapil Gupta, Pradeep K Agarwal

Journal: Food Res Int

PubMed ID: 35651010

Doi: 10.1016/j.foodres.2022.111138

Products & Services: Proteins, Expression, Isolation and Analysis

A multi-epitopes tandem antigen for five types of human adenoviruses and its application in development of multivalent IgM immunochromatographic strip test

Authors: Liqiang Zong, Yong Qi, Wei Li, Wanpeng Shen, Jiameng Li, Ruichen Lv, Nianhong Lu, Susu Zhuang, Qiyuan Gui, Dongming Zhou, Yingjia Xu, Zhao Nan, Yuexi Li

Journal: Diagn Microbiol Infect Dis

PubMed ID: 35378470

Doi: 10.1016/j.diagmicrobio.2022.115675

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Exogenous Annexin 1 inhibits Th17 cell differentiation induced by anti-TNF treatment via activating FPR2 in DSS-induced colitis

Authors: Xing Liu, Lulu Zhou, Wenjie Xin, Zichun Hua

Journal: Int Immunopharmacol

PubMed ID: 35306282

Doi: 10.1016/j.intimp.2022.108685

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Tick Intrastadial Feeding and Its Role on IgE Production in the Murine Model of Alpha-gal Syndrome: The Tick "Transmission" Hypothesis

Authors: L Paulina Maldonado-Ruiz, Gunavanthi D Boorgula, Donghun Kim, Sherry D Fleming, Yoonseong Park

Journal: Front Immunol

PubMed ID: 35309294

Doi: 10.3389/fimmu.2022.844262

Products & Services: Proteins, Expression, Isolation and Analysis

Enabling Efficient Genetic Manipulations in a Rare Actinomycete Shahu

Authors: Jie Li, Baiyang Wang, Qing Yang, Han Si, Yuting Zhao, Yanli Zheng, Wenfang Peng

Journal: Front Microbiol

PubMed ID: 35308340

Doi: 10.3389/fmicb.2022.848964

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Spherical nucleic acids as an infectious disease vaccine platform

Authors: Michelle H Teplensky, Max E Distler, Caroline D Kusmierz, Michael Evangelopoulos, Haley Gula, Derek Elli, Anastasia Tomatsidou, Vlad Nicolaescu, Ian Gelarden, Anjana Yeldandi, Daniel Batlle, Dominique Missiakas, Chad A Mirkin

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35312341

Doi: 10.1073/pnas.2119093119

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A thermostable Cas12b from Brevibacillus leverages one-pot discrimination of SARS-CoV-2 variants of concern

Authors: Long T Nguyen, Nicolas C Macaluso, Brianna L M Pizzano, Melanie N Cash, Jan Spacek, Jan Karasek, Megan R Miller, John A Lednicky, Rhoel R Dinglasan, Marco Salemi, Piyush K Jain

Journal: EBioMedicine

PubMed ID: 35290826

Doi: 10.1016/j.ebiom.2022.103926

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Influence of Proteolysis on the Binding Capacity of Flavor Compounds to Myofibrillar Proteins

Authors: Hao Li, Rui Zheng, Fangfang Zuo, Chengyu Qian, Zhengan Yao, Ruipeng Dong, Di Zhao, Chunbao Li

Journal: Foods

PubMed ID: 35327313

Doi: 10.3390/foods11060891

Products & Services: Proteins, Expression, Isolation and Analysis

Robust, persistent adaptive immune responses to SARS-CoV-2 in the oropharyngeal lymphoid tissue of children

Authors: Kalpana Manthiram, Qin Xu, Pedro Milanez-Almeida, Andrew Martins, Andrea Radtke, Kenneth Hoehn, Jinguo Chen, Can Liu, Juanjie Tang, Gabrielle Grubbs, Sydney Stein, Sabrina Ramelli, Juraj Kabat, Hengameh Behzadpour, Maria Karkanitsa, Jacquelyn Spathies, Heather Kalish, Lela Kardava, Martha Kirby, Foo Cheung, Silvia Preite, Patrick Duncker, Nahir Romero, Diego Preciado, Lyuba Gitman, Galina Koroleva, Grace Smith, Arthur Shaffer, Ian McBain, Stefania Pittaluga, Ronald Germain, Richard Apps, Kaitlyn Sadtler, Susan Moir, Daniel Chertow, Steven Kleinstein, Surender Khurana, John Tsang, Pamela Mudd, Pamela Schwartzberg

Journal: Res Sq

PubMed ID: 35350206

Doi: 10.21203/rs.3.rs-1276578/v1

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An In Vivo Screen to Identify Short Peptide Mimotopes with Enhanced Antitumor Immunogenicity

Authors: Xuedan He, Shiqi Zhou, Breandan Quinn, Dushyant Jahagirdar, Joaquin Ortega, Mark D Long, Scott I Abrams, Jonathan F Lovell

Journal: Cancer Immunol Res

PubMed ID: 34992135

Doi: 10.1158/2326-6066.CIR-21-0332

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The Atypical Chemerin Receptor GPR1 Displays Different Modes of Interaction with β-Arrestins in Humans and Mice with Important Consequences on Subcellular Localization and Trafficking

Authors: Gaetan-Nagim Degroot, Valentin Lepage, Marc Parmentier, Jean-Yves Springael

Journal: Cells

PubMed ID: 35326488

Doi: 10.3390/cells11061037

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Anti-SARS-CoV-2 equine F (Ab') immunoglobulin as a possible therapy for COVID-19

Authors: Viviane Fongaro Botosso, Soraia Attie Calil Jorge, Renato Mancini Astray, Ana Marcia de Sá Guimarães, Monica Beatriz Mathor, Patrícia Dos Santos de Carneiro, Edison Luiz Durigon, Dimas Covas, Danielle Bruna Leal de Oliveira, Ricardo das Neves Oliveira, Durvanei Augusto Maria, Silas Fernandes Eto, Neuza Maria Frazatti Gallina, Giselle Pidde, Carla Cristina Squaiella-Baptistão, Dilza Trevisan Silva, Isadora Maria Villas-Boas, Dayanne Carla Fernandes, Aline Vivian Vatti Auada, Alexandre Campos Banari, Antônio Francisco de Souza Filho, Camila Bianconi, Carla Lilian de Agostini Utescher, Denise Cristina André Oliveira, Douglas Oscar Ceolin Mariano, Flávia Ferreira Barbosa, Giuliana Rondon, Josana Kapronezai, Juliana Galvão da Silva, Mauricio Barbugiani Goldfeder, Priscila Comone, Regis Edgar Castilho Junior, Taiana Tainá Silva Pereira, Fan Hui Wen, Denise V Tambourgi, Ana Marisa Chudzinski-Tavassi

Journal: Sci Rep

PubMed ID: 35273234

Doi: 10.1038/s41598-022-07793-1

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Ubiquitylation is required for the incorporation of the Notch receptor into intraluminal vesicles to prevent prolonged and ligand-independent activation of the pathway

Authors: Björn Schnute, Hideyuki Shimizu, Marvin Lyga, Martin Baron, Thomas Klein

Journal: BMC Biol

PubMed ID: 35264151

Doi: 10.1186/s12915-022-01245-y

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Phosphorylation but Not Oligomerization Drives the Accumulation of Tau with Nucleoporin Nup98

Authors: Lisa Diez, Larisa E Kapinos, Janine Hochmair, Sabrina Huebschmann, Alvaro Dominguez-Baquero, Amelie Vogt, Marija Rankovic, Markus Zweckstetter, Roderick Y H Lim, Susanne Wegmann

Journal: Int J Mol Sci

PubMed ID: 35408855

Doi: 10.3390/ijms23073495

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Tumor-reactive antibodies evolve from non-binding and autoreactive precursors

Authors: Roei D Mazor, Nachum Nathan, Amit Gilboa, Liat Stoler-Barak, Lihee Moss, Inna Solomonov, Assaf Hanuna, Yalin Divinsky, Merav D Shmueli, Hadas Hezroni, Irina Zaretsky, Michael Mor, Ofra Golani, Gad Sabah, Ariella Jakobson-Setton, Natalia Yanichkin, Meora Feinmesser, Daliah Tsoref, Lina Salman, Effi Yeoshoua, Eyal Peretz, Inna Erlich, Netta Mendelson Cohen, Jonathan M Gershoni, Natalia Freund, Yifat Merbl, Gur Yaari, Ram Eitan, Irit Sagi, Ziv Shulman

Journal: Cell

PubMed ID: 35305314

Doi: 10.1016/j.cell.2022.02.012

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Genome-wide investigation of maize RAD51 binding affinity through phage display

Authors: Claire Milsted, Bo Dai, Nelson Garcia, Lu Yin, Yan He, Shahryar Kianian, Wojciech Pawlowski, Changbin Chen

Journal: BMC Genomics

PubMed ID: 35279087

Doi: 10.1186/s12864-022-08419-6

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Defining Biomarkers to Predict Natural Resolution in Shrimp Allergy

Authors: Surapon Piboonpocanun, Suttipong Ittiporn, Pisit Ubonsri, Anchalee Wangtan, Punchama Pacharn, Nualanong Visitsunthorn, Orathai Jirapongsananuruk

Journal: Allergy Asthma Immunol Res

PubMed ID: 35255538

Doi: 10.4168/aair.2022.14.2.210

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Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate

Authors: Ian Seim, Ammon E Posey, Wilton T Snead, Benjamin M Stormo, Daphne Klotsa, Rohit V Pappu, Amy S Gladfelter

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35333653

Doi: 10.1073/pnas.2120799119

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Anti-SARS-CoV-2 Neutralizing Antibody Responses after Two Doses of ChAdOx1 nCoV-19 vaccine (AZD1222) in Healthcare Workers

Authors: Sera Lim, Yuil Lee, Dong Wan Kim, Won Sang Park, Jung Hwan Yoon, Jung Young Lee

Journal: Infect Chemother

PubMed ID: 35384425

Doi: 10.3947/ic.2022.0009

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Design and Characterization of Novel Antibody-Cytokine Fusion Proteins Based on Interleukin-21

Authors: Cesare Di Nitto, Dario Neri, Tobias Weiss, Michael Weller, Roberto De Luca

Journal: Antibodies (Basel)

PubMed ID: 35323193

Doi: 10.3390/antib11010019

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Mxi1-0 Promotes Hypoxic Pulmonary Hypertension ERK/c-Myc-dependent Proliferation of Arterial Smooth Muscle Cells

Authors: Liang Dong, Xinning Liu, Bo Wu, Chengwei Li, Xiaomin Wei, Gulinuer Wumaier, Xiujuan Zhang, Jing Wang, Jingwen Xia, Yuanyuan Zhang, Ruzetuoheti Yiminniyaze, Ning Zhu, Jing Li, Daibing Zhou, Youzhi Zhang, Shuanghui Li, Junzhu Lv, Shengqing Li

Journal: Front Genet

PubMed ID: 35401684

Doi: 10.3389/fgene.2022.810157

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New insights into the resistance mechanism for the BceAB-type transporter SaNsrFP

Authors: Julia Gottstein, Julia Zaschke-Kriesche, Sandra Unsleber, Irina Voitsekhovskaia, Andreas Kulik, Lara V Behrmann, Nina Overbeck, Kai Stühler, Evi Stegmann, Sander H J Smits

Journal: Sci Rep

PubMed ID: 35273305

Doi: 10.1038/s41598-022-08095-2

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Enhanced Cross-Reactive and Polyfunctional Effector-Memory T Cell Responses by ICVAX-a Human PD1-Based Bivalent HIV-1 Gag-p41 Mosaic DNA Vaccine

Authors: Samantha M Y Chen, Yik Chun Wong, Lok Yan Yim, Haoji Zhang, Hui Wang, Grace Chung Yan Lui, Xin Li, Xian Tang, Lin Cheng, Yanhua Du, Qiaoli Peng, Jinlin Wang, Hau-Yee Kwok, Haode Huang, Thomas Tsz-Kan Lau, Denise Pui Chung Chan, Bonnie Chun Kwan Wong, Li Liu, Lisa A Chakrabarti, Shui Shan Lee, Zhiwei Chen

Journal: J Virol

PubMed ID: 35297660

Doi: 10.1128/jvi.02161-21

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Novel Secreted Peptides From var With Immunomodulatory Effects That Enhance Fungal Pathogenesis

Authors: Sameh S M Soliman, Eman M El-Labbad, Ameera Abu-Qiyas, Bahgat Fayed, Alshaimaa M Hamoda, Ahmed M Al-Rawi, Salam Dakalbab, Abdel-Nasser A El-Shorbagi, Mawieh Hamad, Ashraf S Ibrahim, Mohammad G Mohammad

Journal: Front Microbiol

PubMed ID: 35387075

Doi: 10.3389/fmicb.2022.863133

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Identification and Validation of Autophagy-Related Genes in Vitiligo

Authors: Yiwen Yang, Xiuyi Wu, Xiaoli Lu, Chen Wang, Leihong Xiang, Chengfeng Zhang

Journal: Cells

PubMed ID: 35406685

Doi: 10.3390/cells11071116

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Chromatin remodeling factors OsYAF9 and OsSWC4 interact to promote internode elongation in rice

Authors: Aziz Ul Ikram, Fei Zhang, Zuntao Xu, Enze Li, Gan Xue, Shiliang Wang, Cheng Zhang, Yachun Yang, Yanhua Su, Yong Ding

Journal: Plant Physiol

PubMed ID: 35157083

Doi: 10.1093/plphys/kiac031

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Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides

Authors: Prashant Monian, Chikdu Shivalila, Genliang Lu, Mamoru Shimizu, David Boulay, Karley Bussow, Michael Byrne, Adam Bezigian, Arindom Chatterjee, David Chew, Jigar Desai, Frank Favaloro, Jack Godfrey, Andrew Hoss, Naoki Iwamoto, Tomomi Kawamoto, Jayakanthan Kumarasamy, Anthony Lamattina, Amber Lindsey, Fangjun Liu, Richard Looby, Subramanian Marappan, Jake Metterville, Ronelle Murphy, Jeff Rossi, Tom Pu, Bijay Bhattarai, Stephany Standley, Snehlata Tripathi, Hailin Yang, Yuan Yin, Hui Yu, Cong Zhou, Luciano H Apponi, Pachamuthu Kandasamy, Chandra Vargeese

Journal: Nat Biotechnol

PubMed ID: 35256816

Doi: 10.1038/s41587-022-01225-1

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Symmetric and asymmetric receptor conformation continuum induced by a new insulin

Authors: Xiaochun Xiong, Alan Blakely, Jin Hwan Kim, John G Menting, Ingmar B Schäfer, Heidi L Schubert, Rahul Agrawal, Theresia Gutmann, Carlie Delaine, Yi Wolf Zhang, Gizem Olay Artik, Allanah Merriman, Debbie Eckert, Michael C Lawrence, Ünal Coskun, Simon J Fisher, Briony E Forbes, Helena Safavi-Hemami, Christopher P Hill, Danny Hung-Chieh Chou

Journal: Nat Chem Biol

PubMed ID: 35289328

Doi: 10.1038/s41589-022-00981-0

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Induction of SARS-CoV-2 neutralizing antibodies by CoronaVac and BNT162b2 vaccines in naïve and previously infected individuals

Authors: Nicolás A Muena, Tamara García-Salum, Catalina Pardo-Roa, María José Avendaño, Eileen F Serrano, Jorge Levican, Leonardo I Almonacid, Gonzalo Valenzuela, Estefany Poblete, Shirin Strohmeier, Erick Salinas, Andres Muñoz, Denise Haslwanter, Maria Eugenia Dieterle, Rohit K Jangra, Kartik Chandran, Claudia González, Arnoldo Riquelme, Florian Krammer, Nicole D Tischler, Rafael A Medina

Journal: EBioMedicine

PubMed ID: 35366624

Doi: 10.1016/j.ebiom.2022.103972

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A Faster, Novel Technique to Detect COVID-19 Neutralizing Antibodies

Authors: Wei-Huai Chiu, Wei-Yi Kong, Yu-Jang Su, Jyun-Wei Wen, Ciao-Ming Tsai, Chitsung Hong, Pang-Yen Chen, Cheng-Hao Ko

Journal: Med Sci Monit

PubMed ID: 35340017

Doi: 10.12659/MSM.935812

CRISPR/Cas9 Approach to Generate an Auxotrophic BCG Strain for Unmarked Expression of LTAK63 Adjuvant: A Tuberculosis Vaccine Candidate

Authors: Luana Moraes, Monalisa Martins Trentini, Dimitrios Fousteris, Silas Fernandes Eto, Ana Marisa Chudzinski-Tavassi, Luciana Cezar de Cerqueira Leite, Alex Issamu Kanno

Journal: Front Immunol

PubMed ID: 35432328

Doi: 10.3389/fimmu.2022.867195

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Multimodal evaluation of an interphotoreceptor retinoid-binding protein-induced mouse model of experimental autoimmune uveitis

Authors: Jee Myung Yang, KyungA Yun, Jehwi Jeon, Hae Young Yang, Bora Kim, Sunhong Jeong, Junyeop Lee, Wang-Yuhl Oh, Akiyoshi Uemura, Joon Seon Song, Pilhan Kim, Joo Yong Lee

Journal: Exp Mol Med

PubMed ID: 35264718

Doi: 10.1038/s12276-022-00733-z

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The circular RNA circNlgnmediates doxorubicin-inducedcardiac remodeling and fibrosis

Authors: Jindong Xu, William W Du, Nan Wu, Feiya Li, Xiangmin Li, Yizhen Xie, Sheng Wang, Burton B Yang

Journal: Mol Ther Nucleic Acids

PubMed ID: 35402068

Doi: 10.1016/j.omtn.2022.03.007

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Determination of T Cell Responses in Thai Systemic Sclerosis Patients

Authors: Oranit Likhit, Worawit Louthrenoo, Sa-Nga Pattanakitsakul, Aroonroong Suttitheptumrong, Supot Hannongbua, Thanyada Rungrotmongkol, Hiroshi Noguchi, Fujio Takeuchi, Kobporn Boonnak

Journal: J Immunol Res

PubMed ID: 35310606

Doi: 10.1155/2022/5072154

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Structural and functional analysis of the human cone-rod homeobox transcription factor

Authors: Penelope-Marie B Clanor, Christine N Buchholz, Jonathan E Hayes, Michael A Friedman, Andrew M White, Ray A Enke, Christopher E Berndsen

Journal: Proteins

PubMed ID: 35255174

Doi: 10.1002/prot.26332

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Gestational Leucylation Suppresses Embryonic T-Box Transcription Factor 5 Signal and Causes Congenital Heart Disease

Authors: Xuan Zhang , Lian Liu , Wei-Cheng Chen , Feng Wang , Yi-Rong Cheng , Yi-Meng Liu , Yang-Fan Lai , Rui-Jia Zhang , Ya-Nan Qiao , Yi-Yuan Yuan , Yan Lin , Wei Xu , Jing Cao , Yong-Hao Gui , Jian-Yuan Zhao

Journal: Adv Sci (Weinh)

PubMed ID: 35320615

Doi: 10.1002/advs.202201034

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Milk Fat Globule Membrane Alleviates Short Bowel Syndrome-Associated Liver Injury in Rats Through Inhibiting Autophagy and NLRP3 Inflammasome Activation

Authors: Zhicai Yu , Shanshan Huang , Ying Li , Yang Niu , Honghao Chen , Jiang Wu

Journal: Front Nutr

PubMed ID: 35308293

Doi: 10.3389/fnut.2022.758762

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A novel epigenetic marker, Ten-eleven translocation family member 2 (TET2), is identified in the intractable epileptic brain and regulates ATP binding cassette subfamily B member 1 (ABCB1) in the blood-brain barrier

Authors: Fan-Cheng Kong, Li-Qin Lang, Jie Hu, Xia-Ling Zhang, Ming-Kang Zhong, Chun-Lai Ma

Journal: Bioengineered

PubMed ID: 35235761

Doi: 10.1080/21655979.2022.2045838

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The N-terminal helices of amphiphysin and endophilin have different capabilities of membrane remodeling

Authors: Chinta M Aryal, Nhat Nguyen Bui, Likai Song, Jianjun Pan

Journal: Biochim Biophys Acta Biomembr

PubMed ID: 35247332

Doi: 10.1016/j.bbamem.2022.183907

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SARS-CoV-2's high rate of genetic mutation under immune selective pressure: from oropharyngeal B117 to intrapulmonary B1533 in a post-vaccine patient

Authors: Nicolò Musso, Jessica Giuseppina Maugeri, Dafne Bongiorno, Stefano Stracquadanio, Giovanni Bartoloni, Stefania Stefani, Emanuela Daniela Di Stefano

Journal: Int J Infect Dis

PubMed ID: 35247550

Doi: 10.1016/j.ijid.2022.02.044

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Enantioselectivity and key residue of Herbaspirillum huttiense monooxygenase in asymmetric epoxidation of styrenes

Authors: Shuang Dong, Donglin Fan, Qian Liu, Yinyin Meng, Xinyu Liu, Sen Yang, Hui Lin, Na Li, Hongge Chen

Journal: Appl Microbiol Biotechnol

PubMed ID: 35230494

Doi: 10.1007/s00253-022-11843-z

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Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain

Authors: Gang Ye, Bin Liu, Fang Li

Journal: Nat Commun

PubMed ID: 35241675

Doi: 10.1038/s41467-022-28882-9

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mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice

Authors: Zekun Mu, Kevin Wiehe, Kevin O Saunders, Rory Henderson, Derek W Cain, Robert Parks, Diana Martik, Katayoun Mansouri, Robert J Edwards, Amanda Newman, Xiaozhi Lu, Shi-Mao Xia, Amanda Eaton, Mattia Bonsignori, David Montefiori, Qifeng Han, Sravani Venkatayogi, Tyler Evangelous, Yunfei Wang, Wes Rountree, Bette Korber, Kshitij Wagh, Ying Tam, Christopher Barbosa, S Munir Alam, Wilton B Williams, Ming Tian, Frederick W Alt, Norbert Pardi, Drew Weissman, Barton F Haynes

Journal: Cell Rep

PubMed ID: 35294883

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Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy

Authors: Songfa Zhang, Chuan Yan, David G Millar, Qiqi Yang, James M Heather, Adam Langenbucher, Laura T Morton, Sean Sepulveda, Eric Alpert, Lauren R Whelton, Dominique T Zarrella, Mei Guo, Eleanor Minogue, Michael S Lawrence, Bo R Rueda, David R Spriggs, Weiguo Lu, David M Langenau, Mark Cobbold

Journal: Cancer Res

PubMed ID: 34965933

Doi: 10.1158/0008-5472.CAN-21-2200

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Efficient C-to-G Base Editing with Improved Target Compatibility Using Engineered Deaminase-nCas9 Fusions

Authors: Siyu Chen, Zhiquan Liu, Liangxue Lai, Zhanjun Li

Journal: CRISPR J

PubMed ID: 35238619

Doi: 10.1089/crispr.2021.0124

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A rulebook for peptide control of legume-microbe endosymbioses

Authors: Sonali Roy, Lena Maria Müller

Journal: Trends Plant Sci

PubMed ID: 35246381

Doi: 10.1016/j.tplants.2022.02.002

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Understanding desaturation/hydroxylation activity of castor stearoyl Δ9-Desaturase through rational mutagenesis

Authors: Michal Tupec , Martin Culka , Aleš Machara , Stanislav Machácˇek , Daniel Bím , Aleš Svatoš , Lubomír Rulíšek , Iva Pichová

Journal: Elsevier B.V.

Doi: 10.1016/j.csbj.2022.03.010

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HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people

Authors: Jennifer R Habel, Andrea T Nguyen, Louise C Rowntree, Christopher Szeto, Nicole A Mifsud, E Bridie Clemens, Liyen Loh, Weisan Chen, Steve Rockman, Jane Nelson, Jane Davies, Adrian Miller, Steven Y C Tong, Jamie Rossjohn, Stephanie Gras, Anthony W Purcell, Luca Hensen, Katherine Kedzierska, Patricia T Illing

Journal: PLoS Pathog

PubMed ID: 35255101

Doi: 10.1371/journal.ppat.1010337

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Physical Interaction between Cyclin-Dependent Kinase 5 (CDK5) and Clock Factors Affects the Circadian Rhythmicity in Peripheral Oscillators

Authors: Jürgen A Ripperger, Rohit Chavan, Urs Albrecht, Andrea Brenna

Journal: Clocks Sleep

PubMed ID: 35323171

Doi: 10.3390/clockssleep4010017

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RNA chain length and stoichiometry govern surface tension and stability of protein-RNA condensates

Authors: Rabia Laghmach, Ibraheem Alshareedah, Matthew Pham, Muralikrishna Raju, Priya R Banerjee, Davit A Potoyan

Journal: iScience

PubMed ID: 35378855

Doi: 10.1016/j.isci.2022.104105

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Fibroblast growth factor 12 attenuated cardiac remodeling via suppressing oxidative stress

Authors: Aijun Liu, Yonglin Zhang, Shucan Xun, Guangzhi Zhou, Li Lin, Yong Mei

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PubMed ID: 35304156

Doi: 10.1016/j.peptides.2022.170786

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Cytoplasmic domain and enzymatic activity of ACE2 are not required for PI4KB dependent endocytosis entry of SARS-CoV-2 into host cells

Authors: Hang Yang, Huijun Yuan, Xiaohui Zhao, Meng Xun, Shangrui Guo, Nan Wang, Bing Liu, Hongliang Wang

Journal: Virol Sin

PubMed ID: 35272059

Doi: 10.1016/j.virs.2022.03.003

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Changes in genotoxic stress response, ribogenesis and PAP (3'-phosphoadenosine 5'-phosphate) levels are associated with loss of desiccation tolerance in overprimed Medicago truncatula seeds

Authors: Andrea Pagano, Lorena Zannino, Paola Pagano, Enrico Doria, Daniele Dondi, Anca Macovei, Marco Biggiogera, Susana de Sousa Araújo, Alma Balestrazzi

Journal: Plant Cell Environ

PubMed ID: 35188276

Doi: 10.1111/pce.14295

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Expression of a Cytochrome P450 Gene from Bermuda Grass in Soybean Confers Tolerance to Multiple Herbicides

Authors: Ting Zheng, Xiaoxing Yu, Yongzheng Sun, Qing Zhang, Xianwen Zhang, Mengzhen Tang, Chaoyang Lin, Zhicheng Shen

Journal: Plants (Basel)

PubMed ID: 35406929

Doi: 10.3390/plants11070949

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Downregulation of m A writer complex member METTL14 in bladder urothelial carcinoma suppresses tumor aggressiveness

Authors: Catarina Guimarães-Teixeira, João Lobo, Vera Miranda-Gonçalves, Daniela Barros-Silva, Cláudia Martins-Lima, Sara Monteiro-Reis, José Pedro Sequeira, Isa Carneiro, Margareta P Correia, Rui Henrique, Carmen Jerónimo

Journal: Mol Oncol

PubMed ID: 35048498

Doi: 10.1002/1878-0261.13181

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TNF-α stimulation enhances the neuroprotective effects of gingival MSCs derived exosomes in retinal ischemia-reperfusion injury via the MEG3/miR-21a-5p axis

Authors: Ziyu Yu, Yuwen Wen, Nan Jiang, Zhidong Li, Jieying Guan, Yingying Zhang, Caibing Deng, Ling Zhao, Song Guo Zheng, Yingting Zhu, Wenru Su, Yehong Zhuo

Journal: Biomaterials

PubMed ID: 35378413

Doi: 10.1016/j.biomaterials.2022.121484

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Robust Pharmacology of Tmod, a Synthetic Dual-Signal Integrator for Cancer Cell Therapy

Authors: Diane Manry, Kristian Bolanos, Breanna DiAndreth, Jee-Young Mock, Alexander Kamb

Journal: Front Immunol

PubMed ID: 35359952

Doi: 10.3389/fimmu.2022.826747

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Current Status and Future Perspectives on MRNA Drug Manufacturing

Authors: Cameron Webb, Shell Ip, Nuthan V Bathula, Petya Popova, Shekinah K V Soriano, Han Han Ly, Burcu Eryilmaz, Viet Anh Nguyen Huu, Richard Broadhead, Martin Rabel, Ian Villamagna, Suraj Abraham, Vahid Raeesi, Anitha Thomas, Samuel Clarke, Euan C Ramsay, Yvonne Perrie, Anna K Blakney

Journal: Mol Pharm

PubMed ID: 35238565

Doi: 10.1021/acs.molpharmaceut.2c00010

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Development of off-the-shelf hematopoietic stem cell-engineered invariant natural killer T cells for COVID-19 therapeutic intervention

Authors: Yan-Ruide Li, Zachary Spencer Dunn, Gustavo Garcia, Camille Carmona, Yang Zhou, Derek Lee, Jiaji Yu, Jie Huang, Jocelyn T Kim, Vaithilingaraja Arumugaswami, Pin Wang, Lili Yang

Journal: Stem Cell Res Ther

PubMed ID: 35313965

Doi: 10.1186/s13287-022-02787-2

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SARS-CoV-2 mRNA vaccine induced higher antibody affinity and IgG titers against variants of concern in post-partum vs non-post-partum women

Authors: Youri Lee, Gabrielle Grubbs, Sabrina C Ramelli, Andrea R Levine, Allison Bathula, Kapil Saharia, Madeleine Purcell, Shreya Singireddy, Colleen L Dugan, Lindsey Kirchoff, Allison Lankford, Sarah Cipriano, Ryan A Curto, Jocelyn Wu, Katherine Raja, Emily Kelley, Daniel Herr, Kevin M Vannella, Supriya Ravichandran, Juanjie Tang, Anthony Harris, Mohammad Sajadi, Daniel S Chertow, Alison Grazioli, Surender Khurana

Journal: EBioMedicine

PubMed ID: 35301181

Doi: 10.1016/j.ebiom.2022.103940

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