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A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination

Authors: Karen Colwill, Yannick Galipeau, Matthew Stuible, Christian Gervais, Corey Arnold, Bhavisha Rathod, Kento T Abe, Jenny H Wang, Adrian Pasculescu, Mariam Maltseva, Lynda Rocheleau, Martin Pelchat, Mahya Fazel-Zarandi, Mariam Iskilova, Miriam Barrios-Rodiles, Linda Bennett, Kevin Yau, François Cholette, Christine Mesa, Angel X Li, Aimee Paterson, Michelle A Hladunewich, Pamela J Goodwin, Jeffrey L Wrana, Steven J Drews, Samira Mubareka, Allison J McGeer, John Kim, Marc-André Langlois, Anne-Claude Gingras, Yves Durocher

Journal: Clin Transl Immunology

PubMed ID: 35356067

Doi: 10.1002/cti2.1380

Products & Services: Codon Optimization

Degenerate sequence-based CRISPR diagnostic for Crimean-Congo hemorrhagic fever virus

Authors: Hongzhao Li, Alexander Bello, Greg Smith, Dominic M S Kielich, James E Strong, Bradley S Pickering

Journal: PLoS Negl Trop Dis

PubMed ID: 35271569

Doi: 10.1371/journal.pntd.0010285

Products & Services: PCR Cloning and Subcloning

The vaccinia-based Sementis Copenhagen Vector coronavirus disease 2019 vaccine induces broad and durable cellular and humoral immune responses

Authors: Preethi Eldi, Tamara H Cooper, Natalie A Prow, Liang Liu, Gary K Heinemann, Voueleng J Zhang, Abigail D Trinidad, Ruth Marian Guzman-Genuino, Peter Wulff, Leanne M Hobbs, Kerrilyn R Diener, John D Hayball

Journal: Immunol Cell Biol

PubMed ID: 35188985

Doi: 10.1111/imcb.12539

Products & Services: Proteins, Expression, Isolation and Analysis

YfiB: An Outer Membrane Protein Involved in the Virulence of

Authors: Tanuka Sen, Naresh K Verma

Journal: Microorganisms

PubMed ID: 35336228

Doi: 10.3390/microorganisms10030653

Products & Services: Mutant Libraries

Alpha-hydroxytropolones are noncompetitive inhibitors of human RNase H1 that bind to the active site and modulate substrate binding

Authors: Nathan L Ponzar, Razia Tajwar, Nicola Pozzi, John E Tavis

Journal: J Biol Chem

PubMed ID: 35247386

Doi: 10.1016/j.jbc.2022.101790

Products & Services: Mutagenesis Services

Convergent epitope specificities, V gene usage and public clones elicited by primary exposure to SARS-CoV-2 variants

Authors: Noemia S Lima, Maryam Mukhamedova, Timothy S Johnston, Danielle A Wagner, Amy R Henry, Lingshu Wang, Eun Sung Yang, Yi Zhang, Kevina Birungi, Walker P Black, Sijy O'Dell, Stephen D Schmidt, Damee Moon, Cynthia G Lorang, Bingchun Zhao, Man Chen, Kristin L Boswell, Jesmine Roberts-Torres, Rachel L Davis, Lowrey Peyton, Sandeep R Narpala, Sarah O'Connell, Jennifer Wang, Alexander Schrager, Chloe Adrienna Talana, Kwanyee Leung, Wei Shi, Rawan Khashab, Asaf Biber, Tal Zilberman, Joshua Rhein, Sara Vetter, Afeefa Ahmed, Laura Novik, Alicia Widge, Ingelise Gordon, Mercy Guech, I-Ting Teng, Emily Phung, Tracy J Ruckwardt, Amarendra Pegu, John Misasi, Nicole A Doria-Rose, Martin Gaudinski, Richard A Koup, Peter D Kwong, Adrian B McDermott, Sharon Amit, Timothy W Schacker, Itzchak Levy, John R Mascola, Nancy J Sullivan, Chaim A Schramm, Daniel C Douek

Journal: biorxiv

PubMed ID: 35378757

Doi: 10.1101/2022.03.28.486152

Products & Services: Peptide Synthesis

Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold

Authors: Jingjing Chen, Huixin He, Aihuan Wei, Yalei Li, Gang Cheng, Hui Qin, Hanyue Zhong, Hongchun Liu, Meiyu Geng, Aijun Shen, Youhong Hu

Journal: Eur J Med Chem

PubMed ID: 35395439

Doi: 10.1016/j.ejmech.2022.114259

Products & Services: Proteins, Expression, Isolation and Analysis

Rapid Exchange of Stably Bound Protein and DNA Cargo on a DNA Origami Receptor

Authors: James W P Brown, Rokiah G Alford, James C Walsh, Richard E Spinney, Stephanie Y Xu, Sophie Hertel, Jonathan F Berengut, Lisanne M Spenkelink, Antoine M van Oijen, Till Böcking, Richard G Morris, Lawrence K Lee

Journal: ACS Nano

PubMed ID: 35316035

Doi: 10.1021/acsnano.2c00699

Products & Services: Custom Vector Construction

Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate

Authors: Ruixue Wang, Saori Suzuki, Johnathan D Guest, Brigitte Heller, Maricar Almeda, Alexander K Andrianov, Alexander Marin, Roy A Mariuzza, Zhen-Yong Keck, Steven K H Foung, Abdul S Yunus, Brian G Pierce, Eric A Toth, Alexander Ploss, Thomas R Fuerst

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35263223

Doi: 10.1073/pnas.2112008119

Products & Services: PCR Cloning and Subcloning

In situ solid-state NMR study of antimicrobial peptide interactions with erythrocyte membranes

Authors: Kiran Kumar, Mathew Sebastiao, Alexandre A Arnold, Steve Bourgault, Dror E Warschawski, Isabelle Marcotte

Journal: Biophys J

PubMed ID: 35278426

Doi: 10.1016/j.bpj.2022.03.009

Products & Services: Peptide Synthesis

Coupling cell growth and biochemical pathway induction in Saccharomyces cerevisiae for production of (+)-valencene and its chemical conversion to (+)-nootkatone

Authors: Ziling Ye, Yanglei Huang, Bin Shi, Zilei Xiang, Zhu Tian, Man Huang, Liangliang Wu, Zixin Deng, Kun Shen, Tiangang Liu

Journal: Metab Eng

PubMed ID: 35296429

Doi: 10.1016/j.ymben.2022.03.005

Products & Services: PCR and Cloning

Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH

Authors: Alena Stsiapanava, Chenrui Xu, Shunsuke Nishio, Ling Han, Nao Yamakawa, Marta Carroni, Kathryn Tunyasuvunakool, John Jumper, Daniele de Sanctis, Bin Wu, Luca Jovine

Journal: Nat Struct Mol Biol

PubMed ID: 35273390

Doi: 10.1038/s41594-022-00729-3

Products & Services: Mutant Libraries

MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity

Authors: Thilini S Munasinghe, Megan R Edwards, Sofiya Tsimbalyuk, Olivia A Vogel, Kate M Smith, Murray Stewart, Justin K Foster, Loretta A Bosence, David Aragão, Justin A Roby, Christopher F Basler, Jade K Forwood

Journal: Nat Commun

PubMed ID: 35338144

Doi: 10.1038/s41467-022-28851-2

Products & Services: Bacterial Expression

Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer

Authors: Andrea Lopez, Denis E Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A Miranda-Roman, Lars Ulrik Nordstrøm, Swathi-Rao Narayanagari, Ping Chi, Eduardo Vilar, Aristotelis Tsirigos, Evripidis Gavathiotis

Journal: Nat Commun

PubMed ID: 35256598

Doi: 10.1038/s41467-022-28741-7

Products & Services: Catalog Peptides

The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist

Authors: Christian Berg, Michael J Wedemeyer, Motiejus Melynis, Roman R Schlimgen, Lasse H Hansen, Jon Våbenø, Francis C Peterson, Brian F Volkman, Mette M Rosenkilde, Hans R Lüttichau

Journal: PLoS Pathog

PubMed ID: 35271688

Doi: 10.1371/journal.ppat.1010355

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Diagnostic Host Gene Expression Analysis by Quantitative Reverse Transcription Loop-Mediated Isothermal Amplification to Discriminate between Bacterial and Viral Infections

Authors: Melissa C Remmel, Sabrina M Coyle, Mark W Eshoo, Timothy E Sweeney, David C Rawling

Journal: Clin Chem

PubMed ID: 35134876

Doi: 10.1093/clinchem/hvab275

Products & Services: Mammalian Expression

Zymomonas mobilis ZM4 Utilizes an NADP-Dependent Acetaldehyde Dehydrogenase To Produce Acetate

Authors: Magdalena M Felczak, Michaela A TerAvest

Journal: J Bacteriol

PubMed ID: 35258321

Doi: 10.1128/jb.00563-21

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Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization

Authors: Edward A Partlow, Kevin S Cannon, Gunther Hollopeter, Richard W Baker

Journal: Nat Struct Mol Biol

PubMed ID: 35347313

Doi: 10.1038/s41594-022-00749-z

Products & Services: Peptide Synthesis

A simple reverse genetics method to generate recombinant coronaviruses

Authors: Julien Mélade, Géraldine Piorkowski, Franck Touret, Toscane Fourié, Jean-Sélim Driouich, Maxime Cochin, Hawa Sophia Bouzidi, Bruno Coutard, Antoine Nougairède, Xavier de Lamballerie

Journal: EMBO Rep

PubMed ID: 35239997

Doi: 10.15252/embr.202153820

Products & Services: GenParts™ DNA Fragments

Circ_0060531 knockdown ameliorates IL-22-induced keratinocyte damage by binding to miR-330-5p to decrease GAB1 expression

Authors: Quan Shi, Jing Luo, Weiming Chen, Qi He, Jianwen Long, Bo Zhang

Journal: Autoimmunity

PubMed ID: 35293807

Doi: 10.1080/08916934.2022.2037127

Products & Services: Mutant Libraries

Regulation of paternal 5mC oxidation and H3K9me2 asymmetry by ERK1/2 in mouse zygotes

Authors: Baobao Chen, Mingtian Deng, Meng-Hao Pan, Shao-Chen Sun, Honglin Liu

Journal: Cell Biosci

PubMed ID: 35255956

Doi: 10.1186/s13578-022-00758-x

Products & Services: Proteins, Expression, Isolation and Analysis

RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin

Authors: Tal Keren-Kaplan, Amra Sarić, Saikat Ghosh, Chad D Williamson, Rui Jia, Yan Li, Juan S Bonifacino

Journal: Nat Commun

PubMed ID: 35314674

Doi: 10.1038/s41467-022-28952-y

Products & Services: Plasmid DNA Preparation

Age-dependent formation of TMEM106B amyloid filaments in human brains

Authors: Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J Garringer, Ruben Vidal, Grace I Hallinan, Kathy L Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gabor G Kovacs, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino Ghetti, Maria Grazia Spillantini, Benjamin Ryskeldi-Falcon, Alexey G Murzin, Michel Goedert, Sjors H W Scheres

Journal: Nature

PubMed ID: 35344985

Doi: 10.1038/s41586-022-04650-z

Products & Services: GenParts™ DNA Fragments

A peroxisomal heterodimeric enzyme is involved in benzaldehyde synthesis in plants

Authors: Xing-Qi Huang, Renqiuguo Li, Jianxin Fu, Natalia Dudareva

Journal: Nat Commun

PubMed ID: 35292635

Doi: 10.1038/s41467-022-28978-2

Products & Services: Codon Optimization

Performance of Chimeric Antigens in Serological Screening for Chagas Disease in Blood Banks

Authors: Emily Ferreira Dos Santos, Ângelo Antônio Oliveira Silva, Natália Erdens Maron Freitas, Leonardo Maia Leony, Ramona Tavares Daltro, Carlos Antônio de Souza Teles Santos, Maria da Conceição Chagas de Almeida, Fernando Luiz Vieira de Araújo, Paola Alejandra Fiorani Celedon, Marco Aurélio Krieger, Nilson Ivo Tonin Zanchin, Mitermayer Galvão Dos Reis, Fred Luciano Neves Santos

Journal: Front Med (Lausanne)

PubMed ID: 35330587

Doi: 10.3389/fmed.2022.852864

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A novel series of putative Brugia malayi histone demethylase inhibitors as potential anti-filarial drugs

Authors: Tamara Kreiss, Tyler Eck, Brittany Hart, Sreedhar Tummalapalli, David Rotella, John Siekierka

Journal: PLoS Negl Trop Dis

PubMed ID: 35294431

Doi: 10.1371/journal.pntd.0010216

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The protective effects of butorphanol tartrate against homocysteine-induced blood-brain barrier dysfunction

Authors: Sufeng Shen, Jiandong Wang, Qingyuan Zhao, Qiangfu Hu

Journal: Bioengineered

PubMed ID: 35245993

Doi: 10.1080/21655979.2022.2037953

Products & Services: Gene Synthesis

Pull-Down Into Active Inclusion Bodies and Their Application in the Detection of (Poly)-Phosphates and Metal-Ions

Authors: Eva Hrabarova, Martina Belkova, Romana Koszagova, Jozef Nahalka

Journal: Front Bioeng Biotechnol

PubMed ID: 35299638

Doi: 10.3389/fbioe.2022.833192

Products & Services: Gene Synthesis

Sequence-specific destabilization of azurin by tetramethylguanidinium-dipeptide ionic liquids

Authors: Roshani Patel, Austin K Clark, Gabriella DeStefano, Isabella DeStefano, Hunter Gogoj, Erin Gray, Aashka Y Patel, Joshua T Hauner, Gregory A Caputo, Timothy D Vaden

Journal: Biochem Biophys Rep

PubMed ID: 35280523

Doi: 10.1016/j.bbrep.2022.101242

Products & Services: Bacterial Expression

Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination

Authors: Jon Riise, Saskia Meyer, Isaac Blaas, Adity Chopra, Trung T Tran, Marina Delic-Sarac, Malu Lian Hestdalen, Ellen Brodin, Even Holth Rustad, Ke-Zheng Dai, John Torgils Vaage, Lise Sofie Haug Nissen-Meyer, Fredrik Sund, Karin F Wader, Anne T Bjornevik, Peter A Meyer, Gro O Nygaard, Marton König, Sigbjørn Smeland, Fridtjof Lund-Johansen, Johanna Olweus, Arne Kolstad

Journal: Br J Haematol

PubMed ID: 35254660

Doi: 10.1111/bjh.18149

Products & Services: Peptide Synthesis

Polycystin-1 regulates cell proliferation and migration through AKT/mTORC2 pathway in a human craniosynostosis cell model

Authors: Maria A Katsianou, Kostas A Papavassiliou, Antonios N Gargalionis, George Agrogiannis, Penelope Korkolopoulou, Dimitrios Panagopoulos, Marios S Themistocleous, Christina Piperi, Efthimia K Basdra, Athanasios G Papavassiliou

Journal: J Cell Mol Med

PubMed ID: 35285136

Doi: 10.1111/jcmm.17266

Products & Services: Proteins, Expression, Isolation and Analysis

Modified vaccinia Ankara expressing EEHV1A glycoprotein B elicits humoral and cell-mediated immune responses in mice

Authors: Taylor Pursell, Jennifer L Spencer Clinton, Jie Tan, Rongsheng Peng, Paul D Ling

Journal: PLoS ONE

PubMed ID: 35312707

Doi: 10.1371/journal.pone.0265424

Products & Services: Proteins, Expression, Isolation and Analysis

Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity

Authors: Dapeng Li, Simon Brackenridge, Lucy C Walters, Olivia Swanson, Karl Harlos, Daniel Rozbesky, Derek W Cain, Kevin Wiehe, Richard M Scearce, Maggie Barr, Zekun Mu, Robert Parks, Max Quastel, Robert J Edwards, Yunfei Wang, Wes Rountree, Kevin O Saunders, Guido Ferrari, Persephone Borrow, E Yvonne Jones, S Munir Alam, Mihai L Azoitei, Geraldine M Gillespie, Andrew J McMichael, Barton F Haynes

Journal: Commun Biol

PubMed ID: 35347236

Doi: 10.1038/s42003-022-03183-5

Products & Services: Mammalian Expression

RPA-Cas12aDS: A visual and fast molecular diagnostics platform based on RPA-CRISPR-Cas12a method for infectious bursal disease virus detection

Authors: Su-Ya Zheng, Li-Li Ma, Xiao-Li Wang, Li-Xin Lu, Sun-Ting Ma, Bin Xu, Wei Ouyang

Journal: J Virol Methods

PubMed ID: 35288230

Doi: 10.1016/j.jviromet.2022.114523

Products & Services: Plasmid DNA Preparation

Production of indole by Corynebacterium glutamicum microbial cell factories for flavor and fragrance applications

Authors: Melanie Mindt, Arman Beyraghdar Kashkooli, Maria Suarez-Diez, Lenny Ferrer, Tatjana Jilg, Dirk Bosch, Vitor Martins Dos Santos, Volker F Wendisch, Katarina Cankar

Journal: Microb Cell Fact

PubMed ID: 35331232

Doi: 10.1186/s12934-022-01771-y

Products & Services: Bacterial Expression

Targeted Codelivery of Prodigiosin and Simvastatin Using Smart BioMOF: Functionalization by Recombinant Anti-VEGFR1 scFv

Authors: Somayyeh Mirzaeinia, Sedighe Zeinali, Nediljko Budisa, Hamid Reza Karbalaei-Heidari

Journal: Front Bioeng Biotechnol

PubMed ID: 35402395

Doi: 10.3389/fbioe.2022.866275

Products & Services: Gene Synthesis

Computational Design and Biological Evaluation of Analogs of Lupin Peptide P5 Endowed with Dual PCSK9/HMG-CoAR Inhibiting Activity

Authors: Carmen Lammi, Enrico M A Fassi, Jianqiang Li, Martina Bartolomei, Giulia Benigno, Gabriella Roda, Anna Arnoldi, Giovanni Grazioso

Journal: Pharmaceutics

PubMed ID: 35336039

Doi: 10.3390/pharmaceutics14030665

Products & Services: Proteins, Expression, Isolation and Analysis

Phosphoproteome Analysis Identifies a Synaptotagmin-1-Associated Complex Involved in Ischemic Neuron Injury

Authors: Wei Jiang, Pei Zhang, Peng Yang, Na Kang, Junqiang Liu, Yilixiati Aihemaiti, Haijun Tu

Journal: Mol Cell Proteomics

PubMed ID: 35257887

Doi: 10.1016/j.mcpro.2022.100222

Products & Services: Peptide Synthesis

A Single Amino Acid Residue Defines the Difference in NLRP3 Inflammasome Activation between NEK7 and NEK6

Authors: Devon Jeltema, Jihong Wang, Juan Cai, Nathan Kelley, Zhe Yang, Yuan He

Journal: J Immunol

PubMed ID: 35354613

Doi: 10.4049/jimmunol.2101154

Products & Services: Gene Synthesis

Development of spirulina for the manufacture and oral delivery of protein therapeutics

Authors: Benjamin W Jester, Hui Zhao, Mesfin Gewe, Thomas Adame, Lisa Perruzza, David T Bolick, Jan Agosti, Nhi Khuong, Rolf Kuestner, Caitlin Gamble, Kendra Cruickshank, Jeremy Ferrara, Rachelle Lim, Troy Paddock, Colin Brady, Stacey Ertel, Miaohua Zhang, Alex Pollock, Jamie Lee, Jian Xiong, Michael Tasch, Tracy Saveria, David Doughty, Jacob Marshall, Damian Carrieri, Lauren Goetsch, Jason Dang, Nathaniel Sanjaya, David Fletcher, Anissa Martinez, Bryce Kadis, Kristjan Sigmar, Esha Afreen, Tammy Nguyen, Amanda Randolph, Alexandria Taber, Ashley Krzeszowski, Brittney Robinett, David B Volkin, Fabio Grassi, Richard Guerrant, Ryo Takeuchi, Brian Finrow, Craig Behnke, James Roberts

Journal: Nat Biotechnol

PubMed ID: 35314813

Doi: 10.1038/s41587-022-01249-7

Products & Services: Catalog Antibody

Efficacy and Safety of Heterologous Booster Vaccination after Ad5-nCoV (CanSino Biologics) Vaccine: A Preliminary Descriptive Study

Authors: José Francisco Muñoz-Valle, Gabriela Athziri Sánchez-Zuno, Mónica Guadalupe Matuz-Flores, Cristian Oswaldo Hernández-Ramírez, Saúl Alberto Díaz-Pérez, Christian Johana Baños-Hernández, Francisco Javier Turrubiates-Hernández, Alejandra Natali Vega-Magaña, Jorge Hernández-Bello

Journal: Vaccines (Basel)

PubMed ID: 35335032

Doi: 10.3390/vaccines10030400

Spectrum of Phenotypic, Genetic, and Functional Characteristics in Patients With Epilepsy With Pathogenic Variants

Authors: Niklas Schwarz, Simone Seiffert, Manuela Pendziwiat, Annika Verena Rademacher, Tobias Brünger, Ulrike B S Hedrich, Paul B Augustijn, Hartmut Baier, Allan Bayat, Francesca Bisulli, Russell J Buono, Ben Zeev Bruria, Michael G Doyle, Renzo Guerrini, Gali Heimer, Michele Iacomino, Hugh Kearney, Karl Martin Klein, Ioanna Kousiappa, Wolfram S Kunz, Holger Lerche, Laura Licchetta, Ebba Lohmann, Raffaella Minardi, Marie McDonald, Sarah Montgomery, Lejla Mulahasanovic, Renske Oegema, Barel Ortal, Savvas S Papacostas, Francesca Ragona, Tiziana Granata, Phillip S Reif, Felix Rosenow, Annick Rothschild, Paolo Scudieri, Pasquale Striano, Paolo Tinuper, George A Tanteles, Annalisa Vetro, Felix Zahnert, Ethan M Goldberg, Federico Zara, Dennis Lal, Patrick May, Hiltrud Muhle, Ingo Helbig, Yvonne Weber

Journal: Neurology

PubMed ID: 35314505

Doi: 10.1212/WNL.0000000000200660

Products & Services: Proteins, Expression, Isolation and Analysis

Site-specific nanobody-oligonucleotide conjugation for super-resolution imaging

Authors: Laura Teodori, Marjan Omer, Anders Märcher, Mads K Skaanning, Veronica L Andersen, Jesper S Nielsen, Emil Oldenburg, Yuchen Lin, Kurt V Gothelf, Jørgen Kjems

Journal: J Biol Methods

PubMed ID: 35510035

Doi: 10.14440/jbm.2022.381

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Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity

Authors: Lauren B Rodda, Peter A Morawski, Kurt B Pruner, Mitchell L Fahning, Christian A Howard, Nicholas Franko, Jennifer Logue, Julie Eggenberger, Caleb Stokes, Inah Golez, Malika Hale, Michael Gale, Helen Y Chu, Daniel J Campbell, Marion Pepper

Journal: Cell

PubMed ID: 35413241

Doi: 10.1016/j.cell.2022.03.018

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Complement C3a Enhances the Phagocytic Activity of B Cells Through C3aR in a Fish

Authors: Zi-You Ma, Jia-Xin Liang, Wen-Shuo Li, Yuan Sun, Chang-Song Wu, Ya-Zhen Hu, Jun Li, Yong-An Zhang, Xu-Jie Zhang

Journal: Front Immunol

PubMed ID: 35386704

Doi: 10.3389/fimmu.2022.873982

Products & Services: Proteins, Expression, Isolation and Analysis

Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling

Authors: Kim van Kuijk, Jasper A F Demandt, Javier Perales-Patón, Thomas L Theelen, Christoph Kuppe, Elke Marsch, Jenny de Bruijn, Han Jin, Marion J Gijbels, Ljubica Matic, Barend M E Mees, Chris P M Reutelingsperger, Ulf Hedin, Erik A L Biessen, Peter Carmeliet, Andrew H Baker, Rafael K Kramann, Leon J Schurgers, Julio Saez-Rodriguez, Judith C Sluimer

Journal: Cardiovasc Res

PubMed ID: 33913468

Doi: 10.1093/cvr/cvab152

Products & Services: Proteins, Expression, Isolation and Analysis

Therapeutic Effect of Melittin-dKLA Targeting Tumor-Associated Macrophages in Melanoma

Authors: Ik-Hwan Han, Chanmi Jeong, Juwon Yang, Seung-Hyeok Park, Deok-Sang Hwang, Hyunsu Bae

Journal: Int J Mol Sci

PubMed ID: 35328518

Doi: 10.3390/ijms23063094

Products & Services: Biochemicals

Injectable Slow-Release Hydrogel Formulation of a Plant Virus-Based COVID-19 Vaccine Candidate

Authors: Christian Isalomboto Nkanga, Oscar A Ortega-Rivera, Matthew D Shin, Miguel A Moreno-Gonzalez, Nicole F Steinmetz

Journal: Biomacromolecules

PubMed ID: 35344365

Doi: 10.1021/acs.biomac.2c00112

Products & Services: Recombinant Proteins

Evaluation of the Humoral Immune Response of a Heterologous Vaccination between BBIBP-CorV and BNT162b2 with a Temporal Separation of 7 Months, in Peruvian Healthcare Workers with and without a History of SARS-CoV-2 Infection

Authors: Miguel Hueda-Zavaleta, Juan C Gómez de la Torre, José Alonso Cáceres-Del Aguila, Cecilia Muro-Rojo, Nathalia De La Cruz-Escurra, Daniella Arenas Siles, Diana Minchón-Vizconde, Cesar Copaja-Corzo, Fabrizzio Bardales-Silva, Vicente A Benites-Zapata, Alfonso J Rodriguez-Morales

Journal: Vaccines (Basel)

PubMed ID: 35455251

Doi: 10.3390/vaccines10040502

Phage Therapy Potentiates Second-Line Antibiotic Treatment against Pneumonic Plague

Authors: Yaron Vagima, David Gur, Moshe Aftalion, Sarit Moses, Yinon Levy, Arik Makovitzki, Tzvi Holtzman, Ziv Oren, Yaniv Segula, Ella Fatelevich, Avital Tidhar, Ayelet Zauberman, Shahar Rotem, Emanuelle Mamroud, Ida Steinberger-Levy

Journal: Viruses

PubMed ID: 35458417

Doi: 10.3390/v14040688

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Structure-based design and construction of a synthetic phage display nanobody library

Authors: Ernesto Moreno, Mario S Valdés-Tresanco, Andrea Molina-Zapata, Oliberto Sánchez-Ramos

Journal: BMC Res Notes

PubMed ID: 35351202

Doi: 10.1186/s13104-022-06001-7

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Highly Specific Monoclonal Antibody Targeting the Botulinum Neurotoxin Type E Exposed SNAP-25 Neoepitope

Authors: Adva Mechaly, Eran Diamant, Ron Alcalay, Alon Ben David, Eyal Dor, Amram Torgeman, Ada Barnea, Meni Girshengorn, Lilach Levin, Eyal Epstein, Ariel Tennenhouse, Sarel J Fleishman, Ran Zichel, Ohad Mazor

Journal: Antibodies (Basel)

PubMed ID: 35323195

Doi: 10.3390/antib11010021

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COVID-19 Breakthrough Infection after Inactivated Vaccine Induced Robust Antibody Responses and Cross-Neutralization of SARS-CoV-2 Variants, but Less Immunity against Omicron

Authors: Nungruthai Suntronwong, Ritthideach Yorsaeng, Jiratchaya Puenpa, Chompoonut Auphimai, Thanunrat Thongmee, Preeyaporn Vichaiwattana, Sitthichai Kanokudom, Thaneeya Duangchinda, Warangkana Chantima, Pattarakul Pakchotanon, Suvichada Assawakosri, Pornjarim Nilyanimit, Sirapa Klinfueng, Lakkhana Wongsrisang, Donchida Srimuan, Thaksaporn Thatsanatorn, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Yong Poovorawan

Journal: Vaccines (Basel)

PubMed ID: 35335023

Doi: 10.3390/vaccines10030391

Selection and Application of ssDNA Aptamers for Fluorescence Biosensing Detection of Malachite Green

Authors: Miaojia Xie, Zanlin Chen, Fengguang Zhao, Ying Lin, Suiping Zheng, Shuangyan Han

Journal: Foods

PubMed ID: 35327224

Doi: 10.3390/foods11060801

Products & Services: Gene Synthesis

Evaluation of a commercial ELISA as alternative to plaque reduction neutralization test to detect neutralizing antibodies against SARS-CoV-2

Authors: Natalie Hofmann, Marica Grossegesse, Markus Neumann, Lars Schaade, Andreas Nitsche

Journal: Sci Rep

PubMed ID: 35241780

Doi: 10.1038/s41598-022-07597-3

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Leptin secreted from testicular microenvironment modulates hedgehog signaling to augment the endogenous function of Leydig cells

Authors: Himanshu Arora, Rehana Qureshi, Kajal Khodamoradi, Deepa Seetharam, Madhumita Parmar, Derek J Van Booven, Isabelle Catherine Issa, Robert Sackstein, Dolores Lamb, Joshua M Hare, Ranjith Ramasamy

Journal: Cell Death Dis

PubMed ID: 35246515

Doi: 10.1038/s41419-022-04658-3

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Neutralizing antibody responses 300 days after SARS-CoV-2 infection and induction of high antibody titers after vaccination

Authors: Doris Urlaub, Natalie Wolfsdorff, Jan-Erik Hoffmann, Stefanie Dorok, Markus Hoffmann, Moritz Anft, Naomi Pieris, Patrick Günther, Bernhard Schaaf, Uwe Cassens, Peter Bröde, Maren Claus, Lea K Picard, Sabine Wingert, Simone Backes, Deniz Durak, Nina Babel, Stefan Pöhlmann, Frank Renken, Stefan Raunser, Carsten Watzl

Journal: Eur J Immunol

PubMed ID: 35247269

Doi: 10.1002/eji.202149758

Fast and sensitive detection of SARS-CoV-2 RNA using suboptimal protospacer adjacent motifs for Cas12a

Authors: Shuhan Lu, Xiaohan Tong, Yang Han, Kun Zhang, Yizhou Zhang, Qiubing Chen, Junyi Duan, Xinlin Lei, Muhan Huang, Yang Qiu, Ding-Yu Zhang, Xi Zhou, Ying Zhang, Hao Yin

Journal: Nat Biomed Eng

PubMed ID: 35314803

Doi: 10.1038/s41551-022-00861-x

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A novel Lgi1 mutation causes white matter abnormalities and impairs motor coordination in mice

Authors: Xiao-Yu Teng , Ping Hu , Yangyang Chen , Yanyu Zang , Xiaolian Ye, Jingmin Ou , Guiquan Chen , Yun Stone Shi

Journal: FASEB J

PubMed ID: 35167164

Doi: 10.1096/fj.202101652R

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Impact of Modular Architecture on Activity of Glycoside Hydrolase Family 5 Subfamily 8 Mannanases

Authors: Marie Sofie Møller

Journal: Molecules

PubMed ID: 35335278

Doi: 10.3390/molecules27061915

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Non-binary Encoded Nucleic Acid Barcodes Directly Readable by a Nanopore

Authors: Shuanghong Yan , Liying Wang , Yuqin Wang , Zhenyuan Cao , Shanyu Zhang , Xiaoyu Du , Pingping Fan , Panke Zhang , Hong-Yuan Chen , Shuo Huang

Journal: Angew Chem Int Ed Engl

PubMed ID: 35261129

Doi: 10.1002/anie.202116482

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Comparative genomics reveal the convergent evolution of CYP82D and CYP706X members related to flavone biosynthesis in Lamiaceae and Asteraceae

Authors: Ranran Gao, Qian Lou, Lijun Hao, Guihong Qi, Ya Tian, Xiangdong Pu, Chunnian He, Yu Wang, Wenjie Xu, Zhichao Xu, Jingyuan Song

Journal: Plant J

PubMed ID: 34907610

Doi: 10.1111/tpj.15634

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Unusual (2R,6R)-bicyclo[3.1.1]heptane ring construction in fungal a-trans-bergamotene biosynthesis

Authors: Yan-Hua Wen , Tian-Jiao Chen , Long-Yu Jiang , Li Li , Mengbo Guo , Yu Peng , Jing-Jing Chen , Fei Pei , Jin-Ling Yang , Rui-Shan Wang , Ting Gong , Ping Zhu

Journal: iScience

PubMed ID: 35345459

Doi: 10.1016/j.isci.2022.104030

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Structural Insight into KsBcl-2 Mediated Apoptosis Inhibition by Kaposi Sarcoma Associated Herpes Virus

Authors: Chathura D Suraweera , Mark G Hinds , Marc Kvansakul

Journal: Viruses

PubMed ID: 35458468

Doi: 10.3390/v14040738

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Lactobacillus murinus alleviate intestinal ischemia/reperfusion injury through promoting the release of interleukin-10 from M2 macrophages via Toll-like receptor 2 signaling

Authors: Jingjuan Hu, Fan Deng, Bingcheng Zhao, Zebin Lin, Qishun Sun, Xiao Yang, Mei Wu, Shida Qiu, Yu Chen, Zhengzheng Yan, Sidan Luo, Jin Zhao, Weifeng Liu, Cai Li, Ke Xuan Liu

Journal: Microbiome

PubMed ID: 35241180

Doi: 10.1186/s40168-022-01227-w

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Molecular characterization, immunofluorescent localization, and expression levels of two bicarbonate anion transporters in the whitish mantle of the giant clam, Tridacna squamosa, and the implications for light-enhanced shell formation

Authors: Mel V Boo, Caryn Z Pang, Shit F Chew, Yuen K Ip

Journal: Comp Biochem Physiol A Mol Integr Physiol

PubMed ID: 35337976

Doi: 10.1016/j.cbpa.2022.111200

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Fine Mapping of the Region Identified rs7175517 as a Causal Variant Related to BMI in China and the United Kingdom Populations

Authors: Ce Lu, Hai-Jun Wang, Jie-Yun Song, Shuo Wang, Xue-Ying Li, Tao Huang, Hui Wang

Journal: Front Genet

PubMed ID: 35368675

Doi: 10.3389/fgene.2022.838685

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Dynamic observation of SARS-CoV-2 IgM, IgG, and neutralizing antibodies in the development of population immunity through COVID-19 vaccination

Authors: Ruiwei Jiang, Xiaowen Dou, Min Li, Enyun Wang, Jiwen Hu, Dan Xiong, Xiuming Zhang

Journal: J Clin Lab Anal

PubMed ID: 35235705

Doi: 10.1002/jcla.24325

Angiotensin (1-7) peptide replacement therapy with plasma transfusion in COVID-19

Authors: Hasan Onal, Nurcan Ucuncu Ergun, Bengu Arslan, Seyma Topuz, Seda Yilmaz Semerci, Osman Mutluhan Ugurel, Murat Topuzogullari, Ali Kalkan, Sengul Aydin Yoldemir, Nurettin Suner, Ali Kocatas

Journal: Transfus Apher Sci

PubMed ID: 35305923

Doi: 10.1016/j.transci.2022.103418

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Comparative Network Biology Discovers Protein Complexes That Underline Cellular Differentiation in Anabaena sp

Authors: Chen Xu, Bing Wang, Hailu Heng, Jiangmei Huang, Cuihong Wan

Journal: Mol Cell Proteomics

PubMed ID: 35288331

Doi: 10.1016/j.mcpro.2022.100224

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Nup98 Is Subverted from Annulate Lamellae by Hepatitis C Virus Core Protein to Foster Viral Assembly

Authors: Bertrand Boson, Chloé Mialon, Konstanze Schichl, Solène Denolly, François-Loïc Cosset

Journal: MBio

PubMed ID: 35258330

Doi: 10.1128/mbio.02923-21

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Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses

Authors: Eva Mittler, Anna Z Wec, Janne Tynell, Pablo Guardado-Calvo, Julia Wigren-Byström, Laura C Polanco, Cecilia M O'Brien, Megan M Slough, Dafna M Abelson, Alexandra Serris, Mrunal Sakharkar, Gerard Pehau-Arnaudet, Russell R Bakken, James C Geoghegan, Rohit K Jangra, Markus Keller, Larry Zeitlin, Olli Vapalahti, Rainer G Ulrich, Zachary A Bornholdt, Clas Ahlm, Felix A Rey, John M Dye, Steven B Bradfute, Tomas Strandin, Andrew S Herbert, Mattias N E Forsell, Laura M Walker, Kartik Chandran

Journal: Sci Transl Med

PubMed ID: 35294259

Doi: 10.1126/scitranslmed.abl5399

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Structural and mechanistic basis for redox sensing by the cyanobacterial transcription regulator RexT

Authors: Bin Li, Minshik Jo, Jianxin Liu, Jiayi Tian, Robert Canfield, Jennifer Bridwell-Rabb

Journal: Commun Biol

PubMed ID: 35347217

Doi: 10.1038/s42003-022-03226-x

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Neutralizing Monoclonal Antibodies Inhibit SARS-CoV-2 Infection through Blocking Membrane Fusion

Authors: Chia-Jung Li, Tai-Ling Chao, Ting-Yu Chang, Chia-Chun Hsiao, De-Chao Lu, Yi-Wei Chiang, Guan-Chun Lai, Ya-Min Tsai, Jun-Tung Fang, Siman Ieong, Jann-Tay Wang, Sui-Yuan Chang, Shih-Chung Chang

Journal: Microbiol Spectr

PubMed ID: 35293796

Doi: 10.1128/spectrum.01814-21

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Two independent cis-acting elements are required for the guard cell-specific expression of SCAP1, which is essential for late stomatal development

Authors: Kosuke Moriwaki, Shuichi Yanagisawa, Koh Iba, Juntaro Negi

Journal: Plant J

PubMed ID: 35061307

Doi: 10.1111/tpj.15679

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Magnetic field-assisted aligned patterning in an alginate-silk fibroin/nanocellulose composite for guided wound healing

Authors: Keya Ganguly, Hexiu Jin, Sayan Deb Dutta, Dinesh K Patel, Tejal V Patil, Ki-Taek Lim

Journal: Carbohydr Polym

PubMed ID: 35422287

Doi: 10.1016/j.carbpol.2022.119321

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A Novel Anti-CD73 Antibody That Selectively Inhibits Membrane CD73 Shows Antitumor Activity and Induces Tumor Immune Escape

Authors: Markus Kellner, Bettina von Neubeck, Bastian Czogalla, Regina Feederle, Binje Vick, Irmela Jeremias, Reinhard Zeidler

Journal: Biomedicines

PubMed ID: 35453575

Doi: 10.3390/biomedicines10040825

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A novel silk fibroin protein-based fusion system for enhancing the expression of nanobodies in Escherichia coli

Authors: Jianli Yu, Yang Guo, Yi Gu, Xiying Fan, Fei Li, Haipeng Song, Rui Nian, Wenshuai Liu

Journal: Appl Microbiol Biotechnol

PubMed ID: 35243528

Doi: 10.1007/s00253-022-11857-7

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Treatment Regimens for Transplant-Ineligible Patients With Newly Diagnosed Multiple Myeloma: A Systematic Literature Review and Network Meta-analysis

Authors: Thierry Facon, Jesús San-Miguel, Meletios A Dimopoulos, Maria-Victoria Mateos, Michele Cavo, Sophie van Beekhuizen, Zijiao Yuan, João Mendes, Annette Lam, Jianming He, Eric Ammann, Shaji Kumar

Journal: Adv Ther

PubMed ID: 35246820

Doi: 10.1007/s12325-022-02083-8

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Structural polymorphism of coiled-coils from the stalk domain of SARS-CoV-2 spike protein

Authors: Zala Živič, Žiga Strmšek, Marko Novinec, Jurij Lah, San Hadži

Journal: FASEB J

PubMed ID: 35157347

Doi: 10.1096/fj.202101670R

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Molnupiravir and Nirmatrelvir-Ritonavir: Oral COVID Antiviral Drugs

Authors: Louis D Saravolatz, Shawn Depcinski, Mamta Sharma

Journal: Clin Infect Dis

PubMed ID: 35245942

Doi: 10.1093/cid/ciac180

Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF melanoma

Authors: Lorey K Smith, Tiffany Parmenter, Margarete Kleinschmidt, Eric P Kusnadi, Jian Kang, Claire A Martin, Peter Lau, Riyaben Patel, Julie Lorent, David Papadopoli, Anna Trigos, Teresa Ward, Aparna D Rao, Emily J Lelliott, Karen E Sheppard, David Goode, Rodney J Hicks, Tony Tiganis, Kaylene J Simpson, Ola Larsson, Benjamin Blythe, Carleen Cullinane, Vihandha O Wickramasinghe, Richard B Pearson, Grant A McArthur

Journal: Nat Commun

PubMed ID: 35232962

Doi: 10.1038/s41467-022-28705-x

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Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine

Authors: Chung-Yi Wu, Cheng-Wei Cheng, Chih-Chuan Kung, Kuo-Shiang Liao, Jia-Tsrong Jan, Che Ma, Chi-Huey Wong

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35149556

Doi: 10.1073/pnas.2119995119

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Heat Shock Protein A6 Is Especially Involved in Enterovirus 71 Infection

Authors: Jiaoyan Jia, Ge Liu, Jianfeng Zhong, Ran Yan, Xun Song, Kai Zheng, Zhe Ren, Zhendan He, Qinchang Zhu

Journal: Front Microbiol

PubMed ID: 35308396

Doi: 10.3389/fmicb.2022.865644

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Pervasive translation in

Authors: Carol Smith, Jill G Canestrari, Archer J Wang, Matthew M Champion, Keith M Derbyshire, Todd A Gray, Joseph T Wade

Journal: Elife

PubMed ID: 35343439

Doi: 10.7554/eLife.73980

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Characterization of UDP-glycosyltransferase family members reveals how major flavonoid glycoside accumulates in the roots of Scutellaria baicalensis

Authors: Tianlin Pei, Mengxiao Yan, Tian Li, Xiaoqiang Li, Yijia Yin, Mengying Cui, Yumin Fang, Jie Liu, Yu Kong, Ping Xu, Qing Zhao

Journal: BMC Genomics

PubMed ID: 35232374

Doi: 10.1186/s12864-022-08391-1

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Generation of Gal-enhanced bifunctional tumor vaccine

Authors: Jian He, Yu Huo, Zhikun Zhang, Yiqun Luo, Xiuli Liu, Qiaoying Chen, Pan Wu, Wei Shi, Tao Wu, Chao Tang, Huixue Wang, Lan Li, Xiyu Liu, Yong Huang, Yongxiang Zhao, Lu Gan, Bing Wang, Liping Zhong

Journal: Acta Pharm Sin B

PubMed ID: 35865091

Doi: 10.1016/j.apsb.2022.03.002

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Robust, Durable Gene Activation In Vivo via mRNA-Encoded Activators

Authors: Jared P Beyersdorf, Swapnil Bawage, Nahid Iglesias, Hannah E Peck, Ryan A Hobbs, Jay A Wroe, Chiara Zurla, Charles A Gersbach, Philip J Santangelo

Journal: ACS Nano

PubMed ID: 35357116

Doi: 10.1021/acsnano.1c10631

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Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model

Authors: Julie A Zorn, Matthew L Wheeler, Ralston M Barnes, Jim Kaberna, Winse Morishige, Marek Harris, Richard Y-C Huang, Jack Lohre, Yu Ching Chang, Bryant Chau, Kathleen Powers, Ian Schindler, Naveen Neradugomma, Winston Thomas, Xiaoyun Liao, Yinhan Zhou, Sean M West, Feng Wang, Srikanth Kotapati, Guodong Chen, Sayumi Yamazoe, Anastasia Kosenko, Gavin Dollinger, Tim Sproul, Arvind Rajpal, Pavel Strop

Journal: Sci Rep

PubMed ID: 35241687

Doi: 10.1038/s41598-022-06953-7

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Regulator of Actin-Based Motility (RoaM) Downregulates Actin Tail Formation by Rickettsia rickettsii and Is Negatively Selected in Mammalian Cell Culture

Authors: Adam M Nock, Tina R Clark, Ted Hackstadt

Journal: MBio

PubMed ID: 35285700

Doi: 10.1128/mbio.00353-22

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A rationally designed synthetic antimicrobial peptide against Pseudomonas-associated corneal keratitis: Structure-function correlation

Authors: Sk Abdul Mohid, Prerana Sharma, Amani Alghalayini, Tripti Saini, Debarun Datta, Mark D P Willcox, Haydar Ali, Sreyan Raha, Achintya Singha, DongKuk Lee, Nirakar Sahoo, Charles G Cranfield, Sanhita Roy, Anirban Bhunia

Journal: Biophys Chem

PubMed ID: 35605494

Doi: 10.1016/j.bpc.2022.106802

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Circ_0007611 stimulates IL-1 receptor accessory protein to inhibit trophoblast cell proliferation and induce cell apoptosis

Authors: Haiyan Xing, Qing Ding, Hong Lu, Qun Li

Journal: Biol Reprod

PubMed ID: 35238896

Doi: 10.1093/biolre/ioac028

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Enantioselectivity and key residue of Herbaspirillum huttiense monooxygenase in asymmetric epoxidation of styrenes

Authors: Shuang Dong, Donglin Fan, Qian Liu, Yinyin Meng, Xinyu Liu, Sen Yang, Hui Lin, Na Li, Hongge Chen

Journal: Appl Microbiol Biotechnol

PubMed ID: 35230494

Doi: 10.1007/s00253-022-11843-z

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VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir41/51 Inward Rectifier Potassium Channels

Authors: Samantha J McClenahan, Caitlin N Kent, Sujay V Kharade, Elena Isaeva, Jade C Williams, Changho Han, Andrew Terker, Robert Gresham, Roman M Lazarenko, Emily L Days, Ian M Romaine, Joshua A Bauer, Olivier Boutaud, Gary A Sulikowski, Raymond Harris, C David Weaver, Alexander Staruschenko, Craig W Lindsley, Jerod S Denton

Journal: Mol Pharmacol

PubMed ID: 35246480

Doi: 10.1124/molpharm.121.000464

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Atomic resolution dynamics of cohesive interactions in phase-separated Nup98 FG domains

Authors: Eszter E Najbauer, Sheung Chun Ng, Christian Griesinger, Dirk Görlich, Loren B Andreas

Journal: Nat Commun

PubMed ID: 35314668

Doi: 10.1038/s41467-022-28821-8

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Bmi-1 directly upregulates glucose transporter 1 in human gastric adenocarcinoma

Authors: Ying Guo, Guangyu Zhou, Qingjie Ma, Li Zhang, Jiwei Chen

Journal: Open Life Sci

PubMed ID: 35415241

Doi: 10.1515/biol-2022-0024

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Targeting lipophagy in macrophages improves repair in multiple sclerosis

Authors: Mansour Haidar, Melanie Loix, Sam Vanherle, Tess Dierckx, Tim Vangansewinkel, Pascal Gervois, Esther Wolfs, Ivo Lambrichts, Jeroen F J Bogie, Jerome J A Hendriks

Journal: Autophagy

PubMed ID: 35282773

Doi: 10.1080/15548627.2022.2047343

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Characterization of SARS-CoV-2 Variants B16171 (Kappa), B16172 (Delta), and B1618 by Cell Entry and Immune Evasion

Authors: Wenlin Ren, Xiaohui Ju, Mingli Gong, Jun Lan, Yanying Yu, Quanxin Long, Devin J Kenney, Aoife K O'Connell, Yu Zhang, Jin Zhong, Guocai Zhong, Florian Douam, Xinquan Wang, Ailong Huang, Rong Zhang, Qiang Ding

Journal: MBio

PubMed ID: 35266815

Doi: 10.1128/mbio.00099-22

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Design of protein-binding proteins from the target structure alone

Authors: Longxing Cao, Brian Coventry, Inna Goreshnik, Buwei Huang, William Sheffler, Joon Sung Park, Kevin M Jude, Iva Marković, Rameshwar U Kadam, Koen H G Verschueren, Kenneth Verstraete, Scott Thomas Russell Walsh, Nathaniel Bennett, Ashish Phal, Aerin Yang, Lisa Kozodoy, Michelle DeWitt, Lora Picton, Lauren Miller, Eva-Maria Strauch, Nicholas D DeBouver, Allison Pires, Asim K Bera, Samer Halabiya, Bradley Hammerson, Wei Yang, Steffen Bernard, Lance Stewart, Ian A Wilson, Hannele Ruohola-Baker, Joseph Schlessinger, Sangwon Lee, Savvas N Savvides, K Christopher Garcia, David Baker

Journal: Nature

PubMed ID: 35332283

Doi: 10.1038/s41586-022-04654-9

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Antibodies Targeting KSHV gH/gL Reveal Distinct Neutralization Mechanisms

Authors: Thomas Fricke, Anna K Großkopf, Armin Ensser, Marija Backovic, Alexander S Hahn

Journal: Viruses

PubMed ID: 35336948

Doi: 10.3390/v14030541

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