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Vimentin epigenetic deregulation in Bladder Cancer associates with acquisition of invasive and metastatic phenotype through epithelial-to-mesenchymal transition

Authors: Sara Monteiro-Reis, Vera Miranda-Gonçalves, Catarina Guimarães-Teixeira, Cláudia Martins-Lima, João Lobo, Diana Montezuma, Paula C Dias, Helene Neyret-Kahn, Isabelle Bernard-Pierrot, Rui Henrique, Carmen Jerónimo

Journal: Int J Biol Sci

PubMed ID: 36594099

Doi: 10.7150/ijbs.77181

Products & Services: Protein and Antibody Isolation

SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression

Authors: Laura Cioetto-Mazzabò, Francesca Boldrin, Claire Beauvineau, Martin Speth, Alberto Marina, Amine Namouchi, Greta Segafreddo, Mena Cimino, Sandrine Favre-Rochex, Seetha Balasingham, Beatriz Trastoy, Hélène Munier-Lehmann, Gareth Griffiths, Brigitte Gicquel, Marcelo E Guerin, Riccardo Manganelli, Noelia Alonso-Rodríguez

Journal: Nucleic Acids Res

PubMed ID: 36546765

Doi: 10.1093/nar/gkac1173

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Association Between Human Immunodeficiency Virus Viremia and Compromised Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant

Authors: Shi-Hsia Hwa, Jumari Snyman, Mallory Bernstein, Yashica Ganga, Sandile Cele, Daniel Muema, Chee Wah Tan, Khadija Khan, Farina Karim, Willem Hanekom, Leslie Bernstein, Stefan H E Kaufmann, Lin-Fa Wang, Thumbi Ndung'u, Alex Sigal

Journal: J Infect Dis

PubMed ID: 35975942

Doi: 10.1093/infdis/jiac343

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The NOTCH-RIPK4-IRF6-ELOVL4 Axis Suppresses Squamous Cell Carcinoma

Authors: Yue Yan, Marc-Andre Gauthier, Ahmad Malik, Iosifina Fotiadou, Michael Ostrovski, Dzana Dervovic, Logine Ghadban, Ricky Tsai, Gerald Gish, Sampath Kumar Loganathan, Daniel Schramek

Journal: Cancers (Basel)

PubMed ID: 36765696

Doi: 10.3390/cancers15030737

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B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV

Authors: Jacopo Polvere, Massimiliano Fabbiani, Gabiria Pastore, Ilaria Rancan, Barbara Rossetti, Miriam Durante, Sara Zirpoli, Enrico Morelli, Elena Pettini, Simone Lucchesi, Fabio Fiorino, Mario Tumbarello, Annalisa Ciabattini, Francesca Montagnani, Donata Medaglini

Journal: Commun Med (Lond)

PubMed ID: 36717688

Doi: 10.1038/s43856-023-00245-5

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Identification of a Novel Interaction between Prohibitin (PHB-1) and Bovine RuvB-Like AAA ATPase 1

Authors: Prasanna Babu Araveti, Prajna Parimita Kar, Akshay Kuriakose, Achintya Sanju, Kota Arun Kumar, Anand Srivastava

Journal: Microbiol Spectr

PubMed ID: 36651733

Doi: 10.1128/spectrum.02502-22

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A linear DNA encoding the SARS-CoV-2 receptor binding domain elicits potent immune response and neutralizing antibodies in domestic cats

Authors: Antonella Conforti, Elisa Sanchez, Erika Salvatori, Lucia Lione, Mirco Compagnone, Eleonora Pinto, Fabio Palombo, Emanuela D'Acunto, Alessia Muzi, Giuseppe Roscilli, Yuhua Sun, Brian Viscount, James Hayward, Clay Shorrock, Diego G Diel, Joseph A Impellizeri, Luigi Aurisicchio

Journal: Mol Ther Methods Clin Dev

PubMed ID: 36618106

Doi: 10.1016/j.omtm.2022.12.015

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Comprehensive Comparison of Seven SARS-CoV-2-Specific Surrogate Virus Neutralization and Anti-Spike IgG Antibody Assays Using a Live-Virus Neutralization Assay as a Reference

Authors: Marianne Graninger, Claudia Maria Jani, Elisabeth Reuberger, Katja Prüger, Philipp Gaspar, David Niklas Springer, Christian Borsodi, Lisa Weidner, Susanne Rabady, Elisabeth Puchhammer-Stöckl, Christof Jungbauer, Eva Höltl, Judith Helene Aberle, Karin Stiasny, Lukas Weseslindtner

Journal: Microbiol Spectr

PubMed ID: 36622205

Doi: 10.1128/spectrum.02314-22

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Cry51Aa Proteins Are Active against and Show a Mechanism Similar to Pore Formation Model

Authors: Ei Thinzar Soe, Zaw Lin Naing, Caihong Zhang, Lin Lin Niu, Jinrong Tang, Siqi Yu, Zhongwei Ding, Gemei Liang

Journal: J Agric Food Chem

PubMed ID: 36710440

Doi: 10.1021/acs.jafc.2c07244

Products & Services: Protein Electrophoresis and Western

Simultaneous enzyme production, Levan-type FOS synthesis and sugar by-products elimination using a recombinant Pichia pastoris strain expressing a levansucrase-endolevanase fusion enzyme

Authors: Ángela Ávila-Fernández, Silvia Montiel, María Elena Rodríguez-Alegría, Luis Caspeta, Agustín López Munguía

Journal: Microb Cell Fact

PubMed ID: 36703199

Doi: 10.1186/s12934-022-02009-7

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Design of a chimeric ACE-2/Fc-silent fusion protein with ultrahigh affinity and neutralizing capacity for SARS-CoV-2 variants

Authors: Neil M Bodie, Rina Hashimoto, David Connolly, Jennifer Chu, Kazuo Takayama, Bruce D Uhal

Journal: Antib Ther

PubMed ID: 36741194

Doi: 10.1093/abt/tbad001

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Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A

Authors: Dell'Orco D, Dal Cortivo G.

Journal: Sci Rep

PubMed ID: 31882816

Doi: 10.1038/s41598-019-56606-5

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Tissue replication and mucosal swab detection of Sosuga virus in Syrian hamsters in the absence of overt tissue pathology and clinical disease

Authors: Stephen R Welch, Jana M Ritter, Amy J Schuh, Sarah C Genzer, Teresa E Sorvillo, Jessica R Harmon, JoAnn D Coleman-McCray, Shilpi Jain, Punya Shrivastava-Ranjan, Josilene Nascimento Seixas, Lindsey B Estetter, Pamela S Fair, Jonathan S Towner, Joel M Montgomery, César G Albariño, Christina F Spiropoulou, Jessica R Spengler

Journal: Antiviral Res

PubMed ID: 36521633

Doi: 10.1016/j.antiviral.2022.105490

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Prevalence of Anti-PF4 Antibodies After First and Second ChAdOx1 nCoV-19 Vaccinations in Women With Adverse Events: A Brief Report and Literature Review

Authors: Kye Won Choe, Yong Kwan Lim, Oh Joo Kweon, Mi-Kyung Lee, Jin-Won Chung, Hye Ryoun Kim

Journal: Ann Lab Med

PubMed ID: 36544343

Doi: 10.3343/alm.2023.43.3.299

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Cadmium chloride exposure impairs the growth and behavior of Drosophila via ferroptosis

Authors: Yingxia Hu, Haijie Wu, Chenying Lu, Hanqing Xu, Boyang Li, Wanchun Guan, Mingjiang Wu, Yitian Gao, Haibin Tong

Journal: Sci Total Environ

PubMed ID: 36581278

Doi: 10.1016/j.scitotenv.2022.161183

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Polymyxin B neutralizes endotoxin and improves the quality of chicken semen during liquid storage

Authors: Ei Ei Win Maung, Pangda Sopha Sushadi, Atsushi Asano

Journal: Theriogenology

PubMed ID: 36577162

Doi: 10.1016/j.theriogenology.2022.12.027

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Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA

Authors: Seow Neng Chan, Jun Wei Pek

Journal: EMBO Rep

PubMed ID: 36533631

Doi: 10.15252/embr.202154350

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Functional recovery of myocardial infarction by specific EBP-PR1P peptides bridging injectable cardiac extracellular matrix and vascular endothelial growth factor

Authors: Wenxuan Cao, Hong Zhang, Ning Zhou, Runxue Zhou, Xiaojing Zhang, Jia Yin, Jin Deng, Xiang Ao, Chunying Shi

Journal: J Biomed Mater Res A

PubMed ID: 36579729

Doi: 10.1002/jbm.a.37483

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BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network

Authors: Xueqin Sun, Olaf Klingbeil, Bin Lu, Caizhi Wu, Carlos Ballon, Meng Ouyang, Xiaoli S Wu, Ying Jin, Yon Hwangbo, Yu-Han Huang, Tim D D Somerville, Kenneth Chang, Jung Park, Taemoon Chung, Scott K Lyons, Junwei Shi, Hannes Vogel, Michael Schulder, Christopher R Vakoc, Alea A Mills

Journal: Nature

PubMed ID: 36544023

Doi: 10.1038/s41586-022-05551-x

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Identification of selective hepatitis delta virus ribozyme inhibitors by high-throughput screening of small molecule libraries

Authors: Eirini D Tseligka, Stéphanie Conzelmann, Yves Cambet, Tifany Schaer, Francesco Negro, Sophie Clément

Journal: JHEP Rep

PubMed ID: 36704052

Doi: 10.1016/j.jhepr.2022.100652

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Roles of the transcriptional regulators Fts1, YlNrg1, YlTup1, and YlSsn6 in the repression of the yeast-to-filament transition in the dimorphic yeast Yarrowia lipolytica

Authors: Yi-Sheng Mao, Jia-Wen Chen, Zhen-Hua Wang, Meng-Yang Xu, Xiang-Dong Gao

Journal: Mol Microbiol

PubMed ID: 36537557

Doi: 10.1111/mmi.15017

Products & Services: Molecular Biology Reagents

Development of a cockroach (Blattella germanica) qPCR for the objective measurement of exposure at home

Authors: Steffi Rocchi, Benoit Valot, Audrey Laboissière, Audrey Guitton, Emeline Scherer, Laurence Millon, Gabriel Reboux

Journal: Sci Total Environ

PubMed ID: 36526200

Doi: 10.1016/j.scitotenv.2022.160965

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Influence of affinity tags and tobacco PR1a signal peptide on detection, purification and bioactivity analyses of the small oomycete apoplastic effectors

Authors: Jing-Hao Jin, Xue Zhou, Wang Liu, Zi-Hui Zhang, Shen-Xin Huang, Wen-Jing Zhao, Xiao-Ren Chen

Journal: Biotechnol Lett

PubMed ID: 36450976

Doi: 10.1007/s10529-022-03324-0

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SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugate

Authors: Alexander J Garvin , Alexander J Lanz , Joanna R Morris

Journal: Sci Rep

PubMed ID: 36494414

Doi: 10.1038/s41598-022-25665-6

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The effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple

Authors: Runmin Che, Changhai Liu, Qi Wang, Wenyan Tu, Ping Wang, Chao Li, Xiaoqing Gong, Ke Mao, Hao Feng, Lili Huang, Pengmin Li, Fengwang Ma

Journal: Autophagy

PubMed ID: 36449354

Doi: 10.1080/15548627.2022.2153573

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Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis

Authors: Alhaji H. Janneh, Mohamed Faisal Kassir, F. Cansu Atilgan, Stephen Tomlinson, Shikhar Mehrotra, Besim Ogretmen

Journal: Cell Reports

Doi: doi.org/10.1016/j.celrep.2022.111742

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Structure-activity relationship studies for inhibitors for vancomycin-resistant and human carbonic anhydrases

Authors: Weiwei An, Katrina J Holly, Alessio Nocentini, Ryan D Imhoff, Chad S Hewitt, Nader S Abutaleb, Xufeng Cao, Mohamed N Seleem, Claudiu T Supuran, Daniel P Flaherty

Journal: J Enzyme Inhib Med Chem

PubMed ID: 35758212

Doi: 10.1080/14756366.2022.2092729

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mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

Authors: Clifford T H Hayashi , Yi Cao , Leor C Clark , Abhai K Tripathi , Fidel Zavala , Garima Dwivedi , James Knox , Mohamad-Gabriel Alameh , Paulo J C Lin , Ying K Tam , Drew Weissman , Nirbhay Kumar

Journal: npj Vaccines

PubMed ID: 36456563

Doi: 10.1038/s41541-022-00577-8

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Electrical stimulation of piezoelectric BaTiO3 coated Ti6Al4V scaffolds promote antiinflammatory polarization of macrophage and bone repair via MAPK/JNK inhibition and OXPHOS activation

Authors: Hao Wu, Dong Hui, Zhen Tang, Yu Chen, Yichao Liu, Mo Wang, Xinghui Wei, Ning Wang, Shusen Bao, Dongmei Yu, Zhigang Wu, Zhenda Yang, Xiaokang Li, Zheng Guo, Lei Shi

Journal: Biomaterials

Doi: 10.1016/j.biomaterials.2022.121990

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Principles of mitoribosomal small subunit assembly in eukaryotes

Authors: Nathan J Harper, Chloe Burnside, Sebastian Klinge

Journal: Nature

PubMed ID: 36482135

Doi: 10.1038/s41586-022-05621-0

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Disease modification and symptom relief in osteoarthritis using a mutated GCP-2/CXCL6 chemokine

Authors: Sara Caxaria, Nikolaos Kouvatsos, Suzanne E Eldridge, Mario Alvarez-Fallas, Anne-Sophie Thorup, Daniela Cici, Aida Barawi, Ammaarah Arshed, Danielle Strachan, Giulia Carletti, Xinying Huang, Sabah Bharde, Melody Deniz, Jacob Wilson, Bethan L Thomas, Costantino Pitzalis, Francesco Paolo Cantatore, Manasi Sayilekshmy, Shafaq Sikandar, Frank P Luyten, Thomas Pap, Joanna C Sherwood, Anthony J Day, Francesco Dell'Accio

Journal: EMBO Mol Med

PubMed ID: 36507558

Doi: 10.15252/emmm.202216218

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Antibody Response of Heterologous vs Homologous Messenger RNA Vaccine Boosters Against the Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant: Interim Results from the PRIBIVAC Study, a Randomized Clinical Trial

Authors: Xuan Ying Poh, Chee Wah Tan, I Russel Lee, Jean-Marc Chavatte, Siew-Wai Fong, Tessa Prince, Catherine Hartley, Aileen Y Y Yeoh, Suma Rao, Po Ying Chia, Sean W X Ong, Tau Hong Lee, Sapna P Sadarangani, Ray J H Lin, Clarissa Lim, Jefanie Teo, Daniel R X Lim, Wanni Chia, Julian A Hiscox, Lisa F P Ng, Ee Chee Ren, Raymond T P Lin, Laurent Renia, David Chien Lye, Lin-Fa Wang, Barnaby E Young

Journal: Clin Infect Dis

PubMed ID: 35543372

Doi: 10.1093/cid/ciac345

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Early TNF-Dependent Regulation of Excitatory and Inhibitory Synapses on Striatal Direct Pathway Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease

Authors: Julien Chambon, Pragya Komal, Gil M Lewitus, Gina M Kemp, Simone Valade, Houaria Adaïdi, Noura Al Bistami, David Stellwagen

Journal: J Neurosci

PubMed ID: 36517241

Doi: 10.1523/JNEUROSCI.1655-22.2022

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LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway

Authors: Uttam Sharma, Manjit Kaur Rana, Karuna Singh, Aklank Jain

Journal: Biochem Pharmacol

PubMed ID: 36493845

Doi: 10.1016/j.bcp.2022.115372

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Comment on: Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage

Authors: Luiza H Galarion, Justin E Clarke, Harry Schofield, Alex J O'Neill

Journal: J Antimicrob Chemother

PubMed ID: 36416794

Doi: 10.1093/jac/dkac397

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DNA-protein cross-links between abasic DNA damage and mitochondrial transcription factor A (TFAM)

Authors: Wenyan Xu , Jin Tang , Linlin Zhao

Journal: Nucleic Acids Res

PubMed ID: 36583367

Doi: 10.1093/nar/gkac1214

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A BioBricks Metabolic Engineering Platform for the Biosynthesis of Anthracyclinones in Streptomyces coelicolor

Authors: Rongbin Wang , Jennifer Nguyen , Jacob Hecht , Nora Schwartz , Katelyn V Brown , Larissa V Ponomareva, Magdalena Niemczura , Dino van Dissel , Gilles P van Wezel , Jon S Thorson, Mikko Metsä-Ketelä , Khaled A Shaaban, S Eric Nybo

Journal: ACS Synth Biol

PubMed ID: 36378506

Doi: 10.1021/acssynbio.2c00498

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Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling

Authors: Bärbel Schröfelbauer, Patrick K Kimes, Paige Hauke, Charlotte E Reid, Kevin Shao, Sarah J Hill, Rafael Irizarry, William C Hahn

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36574667

Doi: 10.1073/pnas.2206751120

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An epitope-directed selection strategy facilitating the identification of Frizzled receptor selective antibodies

Authors: Qiangqiang Ge, Maikun Teng, Xu Li, Qiong Guo, Yuyong Tao

Journal: Structure

PubMed ID: 36513066

Doi: 10.1016/j.str.2022.11.009

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Long-Term Adaptation to Galactose as a Sole Carbon Source Selects for Mutations Outside the Canonical GAL Pathway

Authors: Artemiza A Martínez, Andrew Conboy, Sean W Buskirk, Daniel A Marad, Gregory I Lang

Journal: J Mol Evol

PubMed ID: 36482210

Doi: 10.1007/s00239-022-10079-9

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Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis

Authors: Li Ma, Junfeng Wei, Yanli Zeng, Junping Liu, Erhui Xiao, Yuehua Kang, Yi Kang

Journal: Drug Deliv

PubMed ID: 35099348

Doi: 10.1080/10717544.2022.2030428

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Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes

Authors: Jakub Benýšek, Michal Buša, Petra Rubešová, Jindřich Fanfrlík, Martin Lepšík, Jiří Brynda, Zuzana Matoušková, Ulrike Bartz, Martin Horn, Michael Gütschow, Michael Mareš

Journal: J Enzyme Inhib Med Chem

PubMed ID: 35144520

Doi: 10.1080/14756366.2021.2024527

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Suchilactone inhibits the growth of acute myeloid leukaemia by inactivating SHP2

Authors: Jingjing Wu, Yuan Deng, Xin Zhang, Jingjing Ma, Xinqi Zheng, Yue Chen

Journal: Pharm Biol

PubMed ID: 34962431

Doi: 10.1080/13880209.2021.2017467

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GmYSL7 controls iron uptake, allocation, and cellular response of nodules in soybean

Authors: Xinying Wu, Yongliang Wang, Qiaohan Ni, Haizhen Li, Xuesong Wu, Zhanxin Yuan, Renhao Xiao, Ziyin Ren, Jingjing Lu, Jinxia Yun, Zhijuan Wang, Xia Li

Journal: J Integr Plant Biol

PubMed ID: 36107150

Doi: 10.1111/jipb.13364

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DeGlyPHER: Highly sensitive site-specific analysis of N-linked glycans on proteins

Authors: Sabyasachi Baboo, Jolene K Diedrich, Salvador Martínez-Bartolomé, Xiaoning Wang, Torben Schiffner, Bettina Groschel, William R Schief, James C Paulson, John R Yates

Journal: Methods Enzymol

PubMed ID: 36948700

Doi: 10.1016/bs.mie.2022.09.004

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Unamplified and Real-Time Label-Free miRNA-21 Detection Using Solution-Gated Graphene Transistors in Prostate Cancer Diagnosis

Authors: Minghua Deng, Zhanpeng Ren, Huibin Zhang, Ziqin Li, Chenglong Xue, Jianying Wang, Dan Zhang, Huan Yang, Xianbao Wang, Jinhua Li

Journal: Adv Sci (Weinh)

PubMed ID: 36480308

Doi: 10.1002/advs.202205886

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A De Novo Missense Variant in TUBG2 in a Child with Global Developmental Delay, Microcephaly, Refractory Epilepsy and Perisylvian Polymicrogyria

Authors: Salini Thulasirajah, Xueqi Wang, Erick Sell, Jorge Dávila, David A Dyment, Kristin D Kernohan

Journal: Genes

PubMed ID: 36672848

Doi: 10.3390/genes14010108

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ADAR1 improved Treg cell function through the miR-21b/Foxp3 axis and inhibits the progression of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

Authors: Yanru Zhao, Xiaoyan Zheng, Miaojing Li, Jing Zhao, Xiaoning Wang, Huachao Zhu

Journal: Int Immunopharmacol

PubMed ID: 36577155

Doi: 10.1016/j.intimp.2022.109620

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Inhibition of autophagy reduces the rate of fluoride-induced LS8 apoptosis via regulating ATG5 and ATG7

Authors: Lin Zhao, Han Wang, Sijia Liu, Tao Xi, Liyuan Wang, Yang Li, Lu Chen, Ruan Jianping, Kristina Xiao Liang

Journal: J Biochem Mol Toxicol

PubMed ID: 36536498

Doi: 10.1002/jbt.23280

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Efficient Production of Epoxy-Norbornane from Norbornene by an Engineered P450 Peroxygenase

Authors: Yu Yan, Chenni Zheng, Wei Song, Jing Wu, Liang Guo, Cong Gao, Jia Liu, Xiulai Chen, Meng Zhu, Liming Liu

Journal: Chembiochem

PubMed ID: 36354378

Doi: 10.1002/cbic.202200529

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Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

Authors: Yunlong Cao, Fanchong Jian, Jing Wang, Yuanling Yu, Weiliang Song, Ayijiang Yisimayi, Jing Wang, Ran An, Xiaosu Chen, Na Zhang, Yao Wang, Peng Wang, Lijuan Zhao, Haiyan Sun, Lingling Yu, Sijie Yang, Xiao Niu, Tianhe Xiao, Qingqing Gu, Fei Shao, Xiaohua Hao, Yanli Xu, Ronghua Jin, Zhongyang Shen, Youchun Wang, Xiaoliang Sunney Xie

Journal: Nature

PubMed ID: 36535326

Doi: 10.1038/s41586-022-05644-7

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Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli

Authors: Ashok R Nayak , Pradip K Singh , Jinlei Zhao , Montserrat Samsó , Michael S Donnenberg

Journal: MBio

PubMed ID: 36326250

Doi: 10.1128/mbio.02270-22

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Intranasal bovine β-defensin-5 enhances antituberculosis immunity in a mouse model by a novel protein-based respiratory mucosal vaccine

Authors: Zhengmin Liang, Hao Li, Mengjin Qu, Yiduo Liu, Yuanzhi Wang, Haoran Wang, Yuhui Dong, Yulan Chen, Xin Ge, Xiangmei Zhou

Journal: Virulence

PubMed ID: 35603910

Doi: 10.1080/21505594.2022.2080342

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Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants

Authors: Qihong Yan, Ruitian Hou, Xiaohan Huang, Yanjun Zhang, Ping He, Yudi Zhang, Banghui Liu, Qian Wang, Haiyue Rao, Xianying Chen, Xinwei Zhao, Xuefeng Niu, Jincun Zhao, Xiaoli Xiong, Ling Chen

Journal: Emerg Microbes Infect

PubMed ID: 36288106

Doi: 10.1080/22221751.2022.2140611

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Molybdopterin biosynthesis pathway contributes to the regulation of SaeRS two-component system by ClpP in

Authors: Na Zhao, Yanan Wang, Junlan Liu, Ziyu Yang, Ying Jian, Hua Wang, Mahmoud Ahmed, Min Li, Taeok Bae, Qian Liu

Journal: Virulence

PubMed ID: 35481455

Doi: 10.1080/21505594.2022.2065961

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High-Throughput and Efficient Intracellular Delivery Method via a Vibration-Assisted Nanoneedle/Microfluidic Composite System

Authors: Xuan Li , Yuan Ma , Yu Xue , Xuanhe Zhang , Linwen Lv , Qianghua Quan , Yiqing Chen , Guoxu Yu , Zhenwei Liang , Xinping Zhang , Ding Weng , Lei Chen , Kui Chen , Xin Han , Jiadao Wang

Journal: ACS Nano

PubMed ID: 36479877

Doi: 10.1021/acsnano.2c07852

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Mir204 and Mir211 suppress synovial inflammation and proliferation in rheumatoid arthritis by targeting Ssrp1

Authors: Qi-Shan Wang , Kai-Jian Fan, Hui Teng , Sijia Chen , Bing-Xin Xu, Di Chen, Ting-Yu Wang

Journal: Elife

Doi: doi.org/10.7554/eLife.78085

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Reduced sensitivity of the SARS-CoV-2 Lambda variant to monoclonal antibodies and neutralizing antibodies induced by infection and vaccination

Authors: Meiyu Wang, Li Zhang, Qianqian Li, Bo Wang, Ziteng Liang, Yeqing Sun, Jianhui Nie, Jiajing Wu, Xiaodong Su, Xiaowang Qu, Yuhua Li, Youchun Wang, Weijin Huang

Journal: Emerg Microbes Infect

PubMed ID: 34818119

Doi: 10.1080/22221751.2021.2008775

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SESAME-catalyzed H3T11 phosphorylation inhibits Dot1-catalyzed H3K79me3 to regulate autophagy and telomere silencing

Authors: Fei He , Qi Yu , Min Wang , Rongsha Wang , Xuanyunjing Gong , Feng Ge , Xilan Yu , Shanshan Li

Journal: Nat Commun

PubMed ID: 36473858

Doi: 10.1038/s41467-022-35182-9

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Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA1 and BA2

Authors: Bingjie Hu, Jasper Fuk-Woo Chan, Huan Liu, Yuanchen Liu, Yue Chai, Jialu Shi, Huiping Shuai, Yuxin Hou, Xiner Huang, Terrence Tsz-Tai Yuen, Chaemin Yoon, Tianrenzheng Zhu, Jinjin Zhang, Wenjun Li, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Bao-Zhong Zhang, Kwok-Yung Yuen, Hin Chu

Journal: Emerg Microbes Infect

PubMed ID: 36039901

Doi: 10.1080/22221751.2022.2117098

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Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions

Authors: Da Zou, Zeming Wu, Xin Yi, Yue Hui, Guangze Yang, Yun Liu, Haofei Wang, Anastasia Brooks, Haolu Wang, Xin Liu, Zhi Ping Xu, Michael S Roberts, Huajian Gao, Chun-Xia Zhao

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36574680

Doi: 10.1073/pnas.2214757120

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The direct binding of AMA1 to erythrocytes defines a RON2-independent invasion pathway

Authors: Seong-Kyun Lee, Leanne M Low, John F Andersen, Lee M Yeoh, Paola Carolina Valenzuela Leon, Damien R Drew, Johannes S P Doehl, Eric Calvo, Louis H Miller, James G Beeson, Karthigayan Gunalan

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36577076

Doi: 10.1073/pnas.2215003120

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A novel method for silkworm cocoons self-degumming and its effect on silk fibers

Authors: Riyuan Wang, Yuancheng Wang, Jianxin Song, Chi Tian, Xinyuan Jing, Ping Zhao, Qingyou Xia

Journal: J Adv Res

PubMed ID: 36572337

Doi: 10.1016/j.jare.2022.12.005

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Structure-function analysis of Cdc25 degradation at the maternal-to-zygotic transition

Authors: Patrick L Ferree, Maggie Xing, Jenny Q Zhang, Stefano Di Talia

Journal: Fly (Austin)

PubMed ID: 35227166

Doi: 10.1080/19336934.2022.2043095

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Immune suppression of vaccine-induced CD8 T-cell responses by gamma retrovirus envelope is mediated by interleukin-10-producing CD4 T cells

Authors: Philip Podschwadt, Anna Malyshkina, Sonja Windmann, Athanasios Papadamakis, Leonie Kerkmann, Dennis Lapuente, Matthias Tenbusch, Mengji Lu, Michael Schindler, Karl Sebastian Lang, Wiebke Hansen, Wibke Bayer

Journal: Front Immunol

PubMed ID: 36605206

Doi: 10.3389/fimmu.2022.934399

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Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics

Authors: Changrong Shi , Qianyu Zhang , Yuying Yao , Fantian Zeng , Chao Du , Sureya Nijiati , Xuejun Wen , Xinyi Zhang , Hongzhang Yang , Haoting Chen , Zhide Guo , Xianzhong Zhang , Jinhao Gao , Weisheng Guo , Xiaoyuan Chen , Zijian Zhou

Journal: Nat Nanotechnol

PubMed ID: 36536041

Doi: 10.1038/s41565-022-01261-7

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Potential of a novel flagellin epitope as a broad-spectrum vaccine candidate against enteric fever

Authors: Shania Vij, Reena Thakur, Laxmi Kumari, Chander Raman Suri, Praveen Rishi

Journal: Microb Pathog

PubMed ID: 36494021

Doi: 10.1016/j.micpath.2022.105936

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Proteolytic activation of human-specific Olduvai domains by the furin protease

Authors: Ashley Pacheco, Aaron Issaian, Jonathan Davis, Nathan Anderson, Travis Nemkov, Natasia Paukovich, Morkos A Henen, Beat Vögeli, James M Sikela, Kirk Hansen

Journal: Int J Biol Macromol

PubMed ID: 36581038

Doi: 10.1016/j.ijbiomac.2022.12.260

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Impact of latency-reversing agents on human macrophage physiology

Authors: Laurent Hany, Marc-Olivier Turmel, Corinne Barat, Michel Ouellet, Michel J Tremblay

Journal: Immun Inflamm Dis

PubMed ID: 36480653

Doi: 10.1002/iid3.590

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Evaluation of immunological responses to third COVID-19 vaccine among people treated with sphingosine receptor-1 modulators and anti-CD20 therapy

Authors: Ilana Katz Sand, Sacha Gnjatic, Florian Krammer, Kevin Tuballes, Juan Manuel Carreño, Sammita Satyanarayan, Susan Filomena, Erin Staker, Johnstone Tcheou, Aaron Miller, Michelle Fabian, Neha Safi, Jamie Nichols, Jasmin Patel, Stephen Krieger, Stephanie Tankou, Sam Horng, Sylvia Klineova, Erin Beck, Miriam Merad, Fred Lublin

Journal: Mult Scler Relat Disord

PubMed ID: 36628884

Doi: 10.1016/j.msard.2022.104486

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Upconversion nanoparticle-based optogenetic nanosystem for photodynamic therapy and cascade gene therapy

Authors: Xinyue Song, Fengyan Li, Feng Tian, Linlin Ren, Qi Wang, Chengfang Jiang, Tao Yan, Shusheng Zhang

Journal: Acta Biomater

PubMed ID: 36494007

Doi: 10.1016/j.actbio.2022.12.002

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Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss

Authors: Alma S Popescu, Claire A Butler, David H Allendorf, Thomas M Piers, Anna Mallach, Julian Roewe, Peter Reinhardt, Alessandro Cinti, Loredana Redaelli, Christophe Boudesco, Laurent Pradier, Jennifer M Pocock, Peter Thornton, Guy C Brown

Journal: Glia

PubMed ID: 36480007

Doi: 10.1002/glia.24318

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Combining intramuscular and intranasal homologous prime-boost with a chimpanzee adenovirus-based COVID-19 vaccine elicits potent humoral and cellular immune responses in mice

Authors: Xingxing Li , Ling Wang , Jingjing Liu , Enyue Fang , Xiaohui Liu , Qinhua Peng , Zelun Zhang , Miao Li , Xinyu Liu , Xiaohong Wu , Danhua Zhao , Lihong Yang , Jia Li , Shouchun Cao , Yanqiu Huang , Leitai Shi , Hongshan Xu , Yunpeng Wang , Yue Suo , Guangzhi Yue , Jianhui Nie , Weijin Huang , Wenjuan Li , Yuhua Li

Journal: Emerg Microbes Infect

PubMed ID: 35775819

Doi: 10.1080/22221751.2022.2097479

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Mitochondrial GPAT-derived LPA controls auxin-dependent embryonic and postembryonic development

Authors: Qianru Jia , Yang Bai , Hui Xu , Qingyun Liu , Wenyan Li , Teng Li , Feng Lin , Like Shen , Wei Xuan , Wenhua Zhang , Qun Zhang

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36454754

Doi: 10.1073/pnas.2212881119

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A frontline, rapid, nucleic acid-based Fusarium circinatum detection system using CRISPR/Cas12a combined with recombinase polymerase amplification

Authors: Zhenpeng Chen , Xiao Yang , Hongming Xia , Cuiping Wu , Jing Yang , Tingting Dai

Journal: Plant Dis

PubMed ID: 36480733

Doi: 10.1094/PDIS-05-22-1234-RE

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clbP Gene, a Potential New Member of the -Lactamase Family

Authors: Adel Azour , Charbel Al-Bayssari , Lucile Pinault , Saïd Azza , Jean-Marc Rolain ,Seydina M. Diene

Journal: Int. J. Mol. Sci

Doi: ijms232415642

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EYFP fusions to HD-Zip IV transcription factors enhance their stability and lead to phenotypic changes in

Authors: Bibek Subedi, Kathrin Schrick

Journal: Plant Signal Behav

PubMed ID: 36154907

Doi: 10.1080/15592324.2022.2119013

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Bazi Bushen capsule attenuates cognitive deficits by inhibiting microglia activation and cellular senescence

Authors: Chuanyuan Ji, Cong Wei, Mengnan Li, Shuang Shen, Shixiong Zhang, Yunlong Hou, Yiling Wu

Journal: Pharm Biol

PubMed ID: 36263579

Doi: 10.1080/13880209.2022.2131839

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A Recombinant Genotype I Japanese Encephalitis Virus Expressing a Gaussia Luciferase Gene for Antiviral Drug Screening Assay and Neutralizing Antibodies Detection

Authors: Chenxi Li , Xuan Chen , Jingbo Hu , Daoyuan Jiang , Demin Cai , Yanhua Li

Journal: Int J Mol Sci

PubMed ID: 36555192

Doi: 10.3390/ijms232415548

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Hepatic neddylation deficiency triggers fatal liver injury via inducing NF-κB-inducing kinase in mice

Authors: Cheng Xu , Hongyi Zhou , Yulan Jin , Khushboo Sahay , Anna Robicsek , Yisong Liu , Kunzhe Dong , Jiliang Zhou , Amanda Barrett , Huabo Su , Weiqin Chen

Journal: Nat Commun

PubMed ID: 36526632

Doi: 10.1038/s41467-022-35525-6

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Cell membrane-camouflaged liposomes and neo-peptide-loaded liposomes with TLR agonist R848 provides a prime and boost strategy for efficient personalized cancer vaccine therapy

Authors: Lu Shi , Hongchen Gu

Journal: Nanomedicine

PubMed ID: 36584738

Doi: 10.1016/j.nano.2022.102648

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Unsterile production of a polyhydroxyalkanoate copolymer by Halomonas cupida J9

Authors: Yujie Liu, Wanwan Zhao, Siqi Wang, Kaiyue Huo, Yaping Chen, Hongfu Guo, Shufang Wang, Ruihua Liu, Chao Yang

Journal: Int J Biol Macromol

PubMed ID: 36347367

Doi: 10.1016/j.ijbiomac.2022.10.275

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Design of a H O -generating P450 fusion protein for high yield fatty acid conversion

Authors: Daniele Giuriato, Danilo Correddu, Gianluca Catucci, Giovanna Di Nardo, Cristiano Bolchi, Marco Pallavicini, Gianfranco Gilardi

Journal: Protein Sci

PubMed ID: 36334042

Doi: 10.1002/pro.4501

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Neutraligands of C5a can potentially occlude the interaction of C5a with the complement receptors C5aR1 and C5aR2

Authors: Aurosikha Das, Manaswini Ghosh, Pulkit Kr Gupta, Soumendra Rana

Journal: J Cell Biochem

PubMed ID: 36565188

Doi: 10.1002/jcb.30360

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Amelioration of ethanol-induced oxidative stress and alcoholic liver disease by in vivo RNAi targeting Cyp2e1

Authors: Yalan Wang, Qiubing Chen, Shuang Wu, Xinyu Sun, Runting Yin, Zhen Ouyang, Hao Yin, Yuan Wei

Journal: Acta Pharmaceutica Sinica B

Doi: 10.1016/j.apsb.2023.01.009

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Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation

Authors: Zhouping Hong , Jyoti Adlakha , Neng Wan , Emily Guinn , Fabian Giska , Kallol Gupta , Thomas J Melia , Karin M Reinisch

Journal: J Cell Biol .

PubMed ID: 36282247

Doi: 10.1083/jcb.202207022

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An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo

Authors: Yajing Zhao , Ningbo Zhao, Yanxing Cai , Hui Zhang, Jia Li, Jiaqi Liu , Chuantao Ye , Yuan Wang , Yamei Dang , Wanying Li , He Liu , Lianqing Zhang , Yuexiang Li , Liang Zhang , Linfeng Cheng , Yangchao Dong , Zhikai Xu , Yingfeng Lei , Lu Lu , Yingjuan Wang , Wei Ye , Fanglin Zhang

Journal: Front Cell Infect Microbiol .

PubMed ID: 36579342

Doi: 10.3389/fcimb.2022.881083

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Human Dectin-1 is -glycosylated and serves as a ligand for C-type lectin receptor CLEC-2

Authors: Shojiro Haji, Taiki Ito, Carla Guenther, Miyako Nakano, Takashi Shimizu, Daiki Mori, Yasunori Chiba, Masato Tanaka, Sushil K Mishra, Janet A Willment, Gordon D Brown, Masamichi Nagae, Sho Yamasaki

Journal: Elife

PubMed ID: 36479973

Doi: 10.7554/eLife.83037

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A chromosome-level genome assembly reveals that tandem-duplicated CYP706V oxidase genes control oridonin biosynthesis in the shoot apex of Isodon rubescens

Authors: Yuwei Sun, Jie Shao, Haili Liu, Hua Wang, Guangyi Wang, Jianhua Li, Yaping Mao, Zhuo Chen, Ke Ma, Lin Xu, Yong Wang

Journal: Mol Plant

PubMed ID: 36518072

Doi: 10.1016/j.molp.2022.12.007

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Molecular cloning and functional characterization of melanocortin-3 receptor in grass carp (Ctenopharyngodon idella)

Authors: Haolin Mo, Huixia Yu, Yang Li, Timothy P C Ezeorba, Zhihao Zhang, Mingxin Yao, Jiajia Yu, Dongmei Xiong, Haixia Liu, Lixin Wang

Journal: Fish Physiol Biochem

PubMed ID: 36547499

Doi: 10.1007/s10695-022-01164-3

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Intracavitary adoptive transfer of IL-12 mRNA-engineered tumor-specific CD8 T cells eradicates peritoneal metastases in mouse models

Authors: Claudia Augusta Di Trani, Assunta Cirella, Leire Arrizabalaga, Ángela Bella, Myriam Fernandez-Sendin, Joan Salvador Russo-Cabrera, Celia Gomar, Irene Olivera, Elizabeth Bolaños, José González-Gomariz, Maite Álvarez, Iñaki Etxeberria, Belen Palencia, Álvaro Teijeira, Ignacio Melero, Pedro Berraondo, Fernando Aranda

Journal: Oncoimmunology

PubMed ID: 36531687

Doi: 10.1080/2162402X.2022.2147317

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Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape

Authors: Roberta Marzi, Jessica Bassi, Chiara Silacci-Fregni, Istvan Bartha, Francesco Muoio, Katja Culap, Nicole Sprugasci, Gloria Lombardo, Christian Saliba, Elisabetta Cameroni, Antonino Cassotta, Jun Siong Low, Alexandra C Walls, Matthew McCallum, M Alejandra Tortorici, John E Bowen, Exequiel A Dellota, Josh R Dillen, Nadine Czudnochowski, Laura Pertusini, Tatiana Terrot, Valentino Lepori, Maciej Tarkowski, Agostino Riva, Maira Biggiogero, Alessandra Franzetti-Pellanda, Christian Garzoni, Paolo Ferrari, Alessandro Ceschi, Olivier Giannini, Colin Havenar-Daughton, Amalio Telenti, Ann Arvin, Herbert W Virgin, Federica Sallusto, David Veesler, Antonio Lanzavecchia, Davide Corti, Luca Piccoli

Journal: iScience

PubMed ID: 36507220

Doi: 10.1016/j.isci.2022.105726

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Brown goat yogurt: Metabolomics, peptidomics, and sensory changes during production

Authors: R Zhang, W Jia

Journal: J Dairy Sci

PubMed ID: 36586795

Doi: 10.3168/jds.2022-22654

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A Rapid Label-Free Disposable Electrochemical Salivary Point-of-Care Sensor for SARS-CoV-2 Detection and Quantification

Authors: Nadia Farsaeivahid, Christian Grenier, Sheyda Nazarian, Ming L Wang

Journal: Sensors (Basel)

PubMed ID: 36617031

Doi: 10.3390/s23010433

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Pseudomonas aeruginosa Promotes Persistence of Stenotrophomonas maltophilia via Increased Adherence to Depolarized Respiratory Epithelium

Authors: Melissa S McDaniel, Natalie R Lindgren, Caitlin E Billiot, Kristina N Valladares, Nicholas A Sumpter, W Edward Swords

Journal: Microbiol Spectr

PubMed ID: 36472421

Doi: 10.1128/spectrum.03846-22

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High anti-SARS-CoV-2 seroprevalence among unvaccinated mother-child pairs from a rural setting in north-eastern Tanzania during the second wave of COVID-19

Authors: Omari Abdul Msemo, Laura Pérez-Alós, Daniel T R Minja, Cecilie Bo Hansen, Samwel Gesase, George Mtove, Joyce Mbwana, Victoria Marie Linderod Larsen, Emilie Caroline Skuladottir Bøgestad, Louise Groth Grunnet, Dirk Lund Christensen, Ib Christian Bygbjerg, David Burgner, Christentze Schmiegelow, Peter Garred, Line Hjort

Journal: IJID Reg

PubMed ID: 36466214

Doi: 10.1016/j.ijregi.2022.11.011

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Endotoxin-free gram-negative bacterium as a system for production and secretion of recombinant proteins

Authors: Ehud Shahar, Ken Emquies, Itai Bloch, Dalia Eliahu, Ran Ben Adiva, Jacob Pitcovski, Itamar Yadid

Journal: Appl Microbiol Biotechnol

PubMed ID: 36445389

Doi: 10.1007/s00253-022-12295-1

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In silico design, production and immunization evaluation of a recombinant bivalent fusion protein candidate vaccine against E coli O157:H7

Authors: Hossein Samiei, Shahram Nazarian, Abass Hajizade, Emad Kordbacheh