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Active Pharmaceutical Ingredient Uptake by Zebrafish (Danio rerio) Oct2 (slc22a2) Transporter Expressed in Xenopus laevis Oocytes

Authors: Elisabeth D Chang, Stewart F Owen, Christer Hogstrand, Nic R Bury

Journal: Environ Toxicol Chem

PubMed ID: 36102855

Doi: 10.1002/etc.5480

Products & Services: Gene Synthesis

Author Correction: Omicron BA4/BA5 escape neutralizing immunity elicited by BA1 infection

Authors: Khadija Khan, Farina Karim, Yashica Ganga, Mallory Bernstein, Zesuliwe Jule, Kajal Reedoy, Sandile Cele, Gila Lustig, Daniel Amoako, Nicole Wolter, Natasha Samsunder, Aida Sivro, James Emmanuel San, Jennifer Giandhari, Houriiyah Tegally, Sureshnee Pillay, Yeshnee Naidoo, Matilda Mazibuko, Yoliswa Miya, Nokuthula Ngcobo, Nithendra Manickchund, Nombulelo Magula, Quarraisha Abdool Karim, Anne von Gottberg, Salim S Abdool Karim, Willem Hanekom, Bernadett I Gosnell, Richard J Lessells, Tulio de Oliveira, Mahomed-Yunus S Moosa, Alex Sigal

Journal: Nat Commun

PubMed ID: 36229444

Doi: 10.1038/s41467-022-33371-0

Products & Services: Monoclonal Antibody Services

FAD-Deficient P187S mutation of NAD(P)H:quinone oxidoreductase 1 (NQO1*2) binds and accelerates β-amyloid aggregation

Authors: Sudipta Panja, David Siegel, Simonetta Camandola, Rafael de Cabo, David Ross, Krishna Mallela

Journal: Biosci Rep

PubMed ID: 36281795

Doi: 10.1042/BSR20220643

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MnO Nanozyme-Mediated CRISPR-Cas12a System for the Detection of SARS-CoV-2

Authors: Lina Wu, Xinjie Wang, Xiangchuan Wu, Shiqi Xu, Ming Liu, Xizhong Cao, Taishan Tang, Xingxu Huang, He Huang

Journal: ACS Appl Mater Interfaces

PubMed ID: 36301087

Doi: 10.1021/acsami.2c14497

Products & Services: Molecular Biology Tools

A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology

Authors: Benjamin F N Campbell, Antje Dittmann, Birgit Dreier, Andreas Plückthun, Shiva K Tyagarajan

Journal: Elife

PubMed ID: 36314779

Doi: 10.7554/eLife.80895

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Sequential Deletions of Interferon Inhibitors MGF110-9L and MGF505-7R Result in Sterile Immunity against the Eurasia Strain of Africa Swine Fever

Authors: Mingyang Ding, Wen Dang, Huanan Liu, Keshan Zhang, Fan Xu, Hong Tian, Huaguo Huang, Zhengwang Shi, Yongjie Sunkang, Xiaodong Qin, Yong Zhang, Haixue Zheng

Journal: J Virol

PubMed ID: 36197109

Doi: 10.1128/jvi.01192-22

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Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy

Authors: Evgenii N Tcyganov, Emilio Sanseviero, Douglas Marvel, Thomas Beer, Hsin-Yao Tang, Peter Hembach, David W Speicher, Qianfei Zhang, Laxminarasimha R Donthireddy, Ali Mostafa, Sabina Tsyganova, Vladimir Pisarev, Terri Laufer, Dmitriy Ignatov, Soldano Ferrone, Christiane Meyer, Hélène Maby-El Hajjami, Daniel E Speiser, Sooner Altiok, Scott Antonia, Xiaowei Xu, Wei Xu, Cathy Zheng, Lynn M Schuchter, Ravi K Amaravadi, Tara C Mitchell, Giorgos C Karakousis, Zhe Yuan, Luis J Montaner, Esteban Celis, Dmitry I Gabrilovich

Journal: Cancer Cell

PubMed ID: 36220073

Doi: 10.1016/j.ccell.2022.09.001

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Chitosan and chitosan oligosaccharide influence digestibility of whey protein isolate through electrostatic interaction

Authors: Linlin Wang, Lilong Wang, Chengrong Wen, Nan Wang, Chunhong Yan, Caihong Shen, Shuang Song

Journal: Int J Biol Macromol

PubMed ID: 36191784

Doi: 10.1016/j.ijbiomac.2022.09.258

Products & Services: Proteins, Expression, Isolation and Analysis

Characteristics of a new carotenoid cleavage dioxygenase NtCCD10 derived from Nicotiana tabacum

Authors: Fan Li, Xiaowei Gong, Yupeng Liang, Lijuan Peng, Xiulin Han, Mengliang Wen

Journal: Planta

PubMed ID: 36251100

Doi: 10.1007/s00425-022-04013-y

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Deciphering the Alphabet of Disorder-Glu and Asp Act Differently on Local but Not Global Properties

Authors: Mette Ahrensback Roesgaard, Jeppe E Lundsgaard, Estella A Newcombe, Nina L Jacobsen, Francesco Pesce, Emil E Tranchant, Søren Lindemose, Andreas Prestel, Rasmus Hartmann-Petersen, Kresten Lindorff-Larsen, Birthe B Kragelund

Journal: Biomolecules

PubMed ID: 36291634

Doi: 10.3390/biom12101426

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Outliers Matter-Correlation between S1 IgG SARS-CoV-2 Antibodies and Neutralizing SARS-CoV-2 Antibodies

Authors: Berthold Hocher, Anne Schönbrunn, Xin Chen, Bernhard K Krämer, Volker von Baehr

Journal: Microorganisms

PubMed ID: 36296343

Doi: 10.3390/microorganisms10102067

Neutralizing Antibody Responses Among Residents and Staff of Long-Term Care Facilities in the State of New Jersey During the First Wave of the COVID-19 Pandemic

Authors: Stephen M Friedman, Jieliang Li, Pauline Thomas, Manisha Gurumurthy, Richard Siderits, Anna Nepomich, Edward Lifshitz

Journal: J Community Health

PubMed ID: 36197535

Doi: 10.1007/s10900-022-01142-z

Insertion of circularly permuted cyan fluorescent protein into the ligand-binding domain of inositol 1,4,5-trisphosphate receptor for enhanced FRET upon binding of fluorescent ligand

Authors: Azmeree Jahan, Mst Tahmina Akter, Kiwamu Takemoto, Tai Oura, Akiko Shitara, Shingo Semba, Akihiro Nezu, Satoshi Suto, Takeharu Nagai, Akihiko Tanimura

Journal: Cell Calcium

PubMed ID: 36335765

Doi: 10.1016/j.ceca.2022.102668

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Long Noncoding RNA LINC00909 Induces Epithelial-Mesenchymal Transition and Contributes to Osteosarcoma Tumorigenesis and Metastasis

Authors: Wanshun Liu, Qi Zhang, Kai Shen, Keran Li, Jie Chang, He Li, Ao Duan, Sheng Zhang, Yumin Huang

Journal: J Oncol

PubMed ID: 36262353

Doi: 10.1155/2022/8660965

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Targeting SARS-CoV-2 infection through CAR-T-like bispecific T cell engagers incorporating ACE2

Authors: Mikail Dogan, Lina Kozhaya, Lindsey Placek, Fatih Karabacak, Mesut Yigit, Derya Unutmaz

Journal: Clin Transl Immunology

PubMed ID: 36285327

Doi: 10.1002/cti2.1421

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A non-canonical RNA-binding domain of the Fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes

Authors: MaKenzie R Scarpitti, Julia E Warrick, Evelyn L Yoder, Michael G Kearse

Journal: J Biol Chem

PubMed ID: 36328245

Doi: 10.1016/j.jbc.2022.102660

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Genome-Wide Identification and Functional Analysis of the Gene Family Responding to Multiple Stressors in

Authors: Mei Zhang, Zhengfeng Wang, Shuguang Jian

Journal: Genes (Basel)

PubMed ID: 36360226

Doi: 10.3390/genes13111988

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The synergism of lytic polysaccharide monooxygenases with lichenase and their co-immobilization on silica nanospheres for green conversion of lichen biomass

Authors: Lixi Cai, Ying Zheng, Yunmeng Chu, Yuanqing Lin, Lixing Liu, Guangya Zhang

Journal: Front Nutr

PubMed ID: 36337671

Doi: 10.3389/fnut.2022.970540

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miR-124-3p Delivered Using Exosomes Attenuates the Keratinocyte Response to IL-17A Stimulation in Psoriasis

Authors: Simin Liu, Jian Gong

Journal: Oxid Med Cell Longev

PubMed ID: 36275890

Doi: 10.1155/2022/6264474

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Recent reconfiguration of an ancient developmental gene regulatory network in Heliocidaris sea urchins

Authors: Phillip L Davidson, Haobing Guo, Jane S Swart, Abdull J Massri, Allison Edgar, Lingyu Wang, Alejandro Berrio, Hannah R Devens, Demian Koop, Paula Cisternas, He Zhang, Yaolei Zhang, Maria Byrne, Guangyi Fan, Gregory A Wray

Journal: Nat Ecol Evol

PubMed ID: 36266460

Doi: 10.1038/s41559-022-01906-9

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Construction of a bioluminescence-based assay for bitter taste receptors (TAS2Rs)

Authors: Shi Min Tan, Wei-Guang Seetoh

Journal: Sci Rep

PubMed ID: 36271274

Doi: 10.1038/s41598-022-21678-3

Products & Services: Mammalian Expression

CRISPR/Cas Precisely Regulated DNA-Templated Silver Nanocluster Fluorescence Sensor for Meat Adulteration Detection

Authors: Jiahui Chen, Jianghua Liu, Di Wu, Ruiyuan Pan, Jian Chen, Yongning Wu, Mingquan Huang, Guoliang Li

Journal: J Agric Food Chem

PubMed ID: 36288511

Doi: 10.1021/acs.jafc.2c04500

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Autophagy Regulates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells Induced by Orthodontic Tension

Authors: Junyi Zheng, Bowen Xu, Kai Yang

Journal: Stem Cells Int

PubMed ID: 36248255

Doi: 10.1155/2022/2983862

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Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques

Authors: Pingchao Li, Qian Wang, Yizi He, Chenchen Yang, Zhengyuan Zhang, Zijian Liu, Bo Liu, Li Yin, Yilan Cui, Peiyu Hu, Yichu Liu, Pingqian Zheng, Wei Wang, Linbing Qu, Caijun Sun, Suhua Guan, Liqiang Feng, Ling Chen

Journal: Emerg Microbes Infect

PubMed ID: 36239345

Doi: 10.1080/22221751.2022.2136538

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Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H αβ tetramer

Authors: Abhinandan V Murthy, Ramita Sulu, Andrey Lebedev, Antti M Salo, Kati Korhonen, Rajaram Venkatesan, Hongmin Tu, Ulrich Bergmann, Janne Jänis, Mikko Laitaoja, Lloyd W Ruddock, Johanna Myllyharju, M Kristian Koski, Rik K Wierenga

Journal: J Biol Chem

PubMed ID: 36265586

Doi: 10.1016/j.jbc.2022.102614

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Bridging the gap between maleate hydratase, citraconase and isopropylmalate isomerase: Insights into the single broad-specific enzyme

Authors: Akila Thirumalai, Padmapriya Ganapathy Raman, Tamilselvan Jayavelu, Ramalingam Subramanian

Journal: Enzyme Microb Technol

PubMed ID: 36272242

Doi: 10.1016/j.enzmictec.2022.110140

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Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion

Authors: Palak N Patel, Thayne H Dickey, Christine S Hopp, Ababacar Diouf, Wai Kwan Tang, Carole A Long, Kazutoyo Miura, Peter D Crompton, Niraj H Tolia

Journal: Nat Commun

PubMed ID: 36202833

Doi: 10.1038/s41467-022-33336-3

Products & Services: Mammalian Expression

HCV Infection Increases the Expression of ACE2 Receptor, Leading to Enhanced Entry of Both HCV and SARS-CoV-2 into Hepatocytes and a Coinfection State

Authors: Tom Domovitz, Samer Ayoub, Michal Werbner, Joel Alter, Lee Izhaki Tavor, Yfat Yahalom-Ronen, Evgeny Tikhonov, Tomer Meirson, Yaakov Maman, Nir Paran, Tomer Israely, Moshe Dessau, Meital Gal-Tanamy

Journal: Microbiol Spectr

PubMed ID: 36314945

Doi: 10.1128/spectrum.01150-22

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Accelerated DNA vaccine regimen provides protection against Crimean-Congo hemorrhagic fever virus challenge in a macaque model

Authors: David W Hawman, Kimberly Meade-White, Shanna Leventhal, Sofia Appelberg, Gustaf Ahlén, Negin Nikouyan, Chad Clancy, Brian Smith, Patrick Hanley, Jamie Lovaglio, Ali Mirazimi, Matti Sällberg, Heinz Feldmann

Journal: Mol Ther

PubMed ID: 36184852

Doi: 10.1016/j.ymthe.2022.09.016

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Safety, efficacy, and DIVA feasibility on a novel live attenuated classical swine fever marker vaccine candidate

Authors: Chao Tong, Huanhuan Liu, Jiaying Wang, Yanyong Sun, Ning Chen

Journal: Vaccine

PubMed ID: 36328881

Doi: 10.1016/j.vaccine.2022.10.035

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Mannose and Hyaluronic Acid Dual-Modified Iron Oxide Enhances Neoantigen-Based Peptide Vaccine Therapy by Polarizing Tumor-Associated Macrophages

Authors: Ying Nie , Lu Shi , Yanan Zhang , Yunfei Guo , Hongchen Gu

Journal: Cancers

PubMed ID: 36291890

Doi: /10.3390/cancers14205107

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Structural basis of TRPV3 inhibition by an antagonist

Authors: Junping Fan, Linghan Hu, Zongwei Yue, Daohong Liao, Fusheng Guo, Han Ke, Daohua Jiang, Yong Yang, Xiaoguang Lei

Journal: Nat Chem Biol

PubMed ID: 36302896

Doi: 10.1038/s41589-022-01166-5

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Identifying a novel role for the master regulator Tal1 in the Endothelial to Hematopoietic Transition

Authors: Yasmin Natalia Serina Secanechia, Isabelle Bergiers, Matt Rogon, Christian Arnold, Nicolas Descostes, Stephanie Le, Natalia López-Anguita, Kerstin Ganter, Chrysi Kapsali, Lea Bouilleau, Aaron Gut, Auguste Uzuotaite, Ayshan Aliyeva, Judith B Zaugg, Christophe Lancrin

Journal: Sci Rep

PubMed ID: 36217016

Doi: 10.1038/s41598-022-20906-0

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Amphiphile-CpG vaccination induces potent lymph node activation and COVID-19 immunity in mice and non-human primates

Authors: Lochana M Seenappa, Aniela Jakubowski, Martin P Steinbuck, Erica Palmer, Christopher M Haqq, Crystal Carter, Jane Fontenot, Francois Villinger, Lisa K McNeil, Peter C DeMuth

Journal: npj Vaccines

PubMed ID: 36307453

Doi: 10.1038/s41541-022-00560-3

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Development of Enzymatic Depletion Methods for Preparation of Small Extracellular Vesicles with Long Blood-Circulation Half-Life

Authors: Yuki Kobayashi, Shimpei Kitamura, Yuki Takahashi, Yoshinobu Takakura

Journal: Pharm Res

PubMed ID: 36195822

Doi: 10.1007/s11095-022-03405-9

Products & Services: Proteins, Expression, Isolation and Analysis

Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP

Authors: Maria A Schumacher, Mirka E Wörmann, Max Henderson, Raul Salinas, Andreas Latoscha, Mahmoud M Al-Bassam, Kumar Siddharth Singh, Elaine Barclay, Katrin Gunka, Natalia Tschowri

Journal: Nat Commun

PubMed ID: 36192422

Doi: 10.1038/s41467-022-33537-w

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Engineering a precise adenine base editor with minimal bystander editing

Authors: Liang Chen, Shun Zhang, Niannian Xue, Mengjia Hong, Xiaohui Zhang, Dan Zhang, Jing Yang, Sijia Bai, Yifan Huang, Haowei Meng, Hao Wu, Changming Luan, Biyun Zhu, Gaomeng Ru, Hongyi Gao, Liping Zhong, Meizhen Liu, Mingyao Liu, Yiyun Cheng, Chengqi Yi, Liren Wang, Yongxiang Zhao, Gaojie Song, Dali Li

Journal: Nat Chem Biol

PubMed ID: 36229683

Doi: 10.1038/s41589-022-01163-8

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Expression changes of non-specific cytotoxic cell receptor (NCCRP1) and proliferation and migration of NCCs post-Nocardia seriolae infection in Northern Snakehead

Authors: Jian Teng, Meng Yao Cui, Yan Zhao, Hong Ju Chen, Wen Jing Du, Liang Yi Xue, Xiang Shan Ji

Journal: Dev Comp Immunol

PubMed ID: 36240859

Doi: 10.1016/j.dci.2022.104576

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miR-275/305 cluster is essential for maintaining energy metabolic homeostasis by the insulin signaling pathway in Bactrocera dorsalis

Authors: Junfei Xie, Hao Chen, Wenping Zheng, Zhaohui Cai, Xiaoxue Li, Hongyu Zhang

Journal: PLOS Genetics

Doi: 10.1371/journal.pgen.1010418

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TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model

Authors: Nunziata Maio, Sara Cherry, David C Schultz, Brett L Hurst, W Marston Linehan, Tracey A Rouault

Journal: iScience

PubMed ID: 36093377

Doi: 10.1016/j.isci.2022.105074

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Resistance of SARS-CoV-2 Omicron variant to convalescent and CoronaVac vaccine plasma

Authors: Yingdan Wang, Yunping Ma, Yan Xu, Jiangyan Liu, Xiang Li, Yuyuan Chen, Yan Chen, Jun Xie, Lianbo Xiao, Zheng Xiang, Fan Wu, Jinghe Huang

Journal: Emerg Microbes Infect

PubMed ID: 35001836

Doi: 10.1080/22221751.2022.2027219

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TNP Analogues Inhibit the Virulence Promoting IP3-4 Kinase Arg1 in the Fungal Pathogen Cryptococcus neoformans

Authors: Desmarini Desmarini, Daniel Truong, Lorna Wilkinson-White, Chandrika Desphande, Mario Torrado, Joel P Mackay, Jacqueline M Matthews, Tania C Sorrell, Sophie Lev, Philip E Thompson, Julianne Teresa Djordjevic

Journal: Biomolecules

PubMed ID: 36291735

Doi: 10.3390/biom12101526

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Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-β-mannans

Authors: Marcele P Martins, Mariana A B Morais, Gabriela F Persinoti, Rafael H Galinari, Li Yu, Yoshihisa Yoshimi, Fernanda B Passos Nunes, Tatiani B Lima, Shayla F Barbieri, Joana L M Silveira, Vincent Lombard, Nicolas Terrapon, Paul Dupree, Bernard Henrissat, Mário T Murakami

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 36322419

Doi: 10.1107/S2059798322009561

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MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases

Authors: Zahra Mohtashami, Mithalesh K Singh, Nasim Salimiaghdam, Mustafa Ozgul, M Cristina Kenney

Journal: Int J Mol Sci

PubMed ID: 36233287

Doi: 10.3390/ijms231911991

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Velcrin-induced selective cleavage of tRNA(TAA) by SLFN12 causes cancer cell death

Authors: Sooncheol Lee, Stephanie Hoyt, Xiaoyun Wu, Colin Garvie, Joseph McGaunn, Mrinal Shekhar, Marcus Tötzl, Matthew G Rees, Andrew D Cherniack, Matthew Meyerson, Heidi Greulich

Journal: Nat Chem Biol

PubMed ID: 36302897

Doi: 10.1038/s41589-022-01170-9

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CD4-1 and CD8α T lymphocytes subsets in spotted sea bass (Lateolabrax maculatus) and comparison on antigenicity of T lymphocytes subsets in other three marine fish species

Authors: Xiaoyu Jiang, Jing Xing, Xiaoqian Tang, Xiuzhen Sheng, Heng Chi, Wenbin Zhan

Journal: Fish Shellfish Immunol

PubMed ID: 36210001

Doi: 10.1016/j.fsi.2022.10.004

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Loss of Chemerin in Rhabdomyosarcoma Cells Polarizes Adjacent Monocytes to an Immunosuppressive Phenotype

Authors: Rui Sun, Jia Le Lin, Man Si Cheng, Kang Yi Lee, Thilo Spruss, Christa Buechler, Herbert Schwarz

Journal: Biomedicines

PubMed ID: 36289872

Doi: 10.3390/biomedicines10102610

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Impairment of antiviral immune response and disruption of cellular functions by SARS-CoV-2 ORF7a and ORF7b

Authors: Tránsito García-García, Raúl Fernández-Rodríguez, Natalia Redondo, Ana de Lucas-Rius, Sara Zaldívar-López, Blanca Dies López-Ayllón, José M Suárez-Cárdenas, Ángeles Jiménez-Marín, María Montoya, Juan J Garrido

Journal: iScience

PubMed ID: 36310646

Doi: 10.1016/j.isci.2022.105444

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New mescaline-related N-acylhydrazone and its unsubstituted benzoyl derivative: Promising metallophores for copper-associated deleterious effects relief in Alzheimer's disease

Authors: Alessandra Carvalho, Barbara Marinho Barbosa, Jesica S Flores, Phelippe do Carmo Gonçalves, Renata Diniz, Yraima Cordeiro, Claudio O Fernández, Daphne S Cukierman, Nicolás A Rey

Journal: J Inorg Biochem

PubMed ID: 36396525

Doi: 10.1016/j.jinorgbio.2022.112033

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The potential effects and mechanisms of Gegen Qinlian Decoction in oxaliplatin-resistant colorectal cancer based on network pharmacology

Authors: Xiang Lin, Li Xu, Huicheng Tan, Xinyi Zhang, Huan Shao, Li Yao, Xuan Huang

Journal: Heliyon

PubMed ID: 36353164

Doi: 10.1016/j.heliyon.2022.e11305

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Modification of Hinge/Transmembrane and Signal Transduction Domains Improves the Expression and Signaling Threshold of GXMR-CAR Specific to spp

Authors: Matheus Henrique Dos Santos, Michele Procópio Machado, Pappanaicken R Kumaresan, Thiago Aparecido da Silva

Journal: Cells

PubMed ID: 36359781

Doi: 10.3390/cells11213386

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IFITM3 promotes NiV envelope protein-mediated entry into MDCK cells and interacts with the fusion subunit of the F protein

Authors: Wang Xu, Shou-Wen Du, Le-Tian Li, Xiao-Shuang Shi, Jia-Min Wang, Ti-Yuan Li, Ning-Yi Jin, Chang Li

Journal: Int J Biochem Cell Biol

PubMed ID: 36330888

Doi: 10.1016/j.biocel.2022.106325

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Nitric oxide-driven modifications of lipoic arm inhibit α-ketoacid dehydrogenases

Authors: Gretchen L Seim, Steven V John, Nicholas L Arp, Zixiang Fang, David J Pagliarini, Jing Fan

Journal: Nat Chem Biol

PubMed ID: 36266351

Doi: 10.1038/s41589-022-01153-w

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CD8+ T cell clonotypes from prior SARS-CoV-2 infection predominate during the cellular immune response to mRNA vaccination

Authors: Emily S Ford, Koshlan Mayer-Blackwell, Lichen Jing, Anton M Sholukh, Russell St Germain, Emily L Bossard, Hong Xie, Thomas H Pulliam, Saumya Jani, Stacy Selke, Carlissa J Burrow, Christopher L McClurkan, Anna Wald, Michael R Holbrook, Brett Eaton, Elizabeth Eudy, Michael Murphy, Elena Postnikova, Harlan S Robins, Rebecca Elyanow, Rachel M Gittelman, Matyas Ecsedi, Elise Wilcox, Aude G Chapuis, Andrew Fiore-Gartland, David M Koelle

Journal: Res Sq

PubMed ID: 36263073

Doi: 10.21203/rs.3.rs-2146712/v1

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A bZIP transcription factor (CiFD) regulates drought and low temperature induced flowering by alternative splicing in citrus

Authors: Li-Xia Ye, Yan-Mei Wu, Jin-Xia Zhang, Jin-Xin Zhang, Huan Zhou, Ren-Fang Zeng, Wei-Xuan Zheng, Mei-Qi Qiu, Jing-Jing Zhou, Zong-Zhou Xie, Chun-Gen Hu, Jin-Zhi Zhang

Journal: J Integr Plant Biol

PubMed ID: 36250511

Doi: 10.1111/jipb.13390

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Epitope of antiphospholipid antibodies retrieved from peptide microarray based on R39-R43 of β2-glycoprotein I

Authors: Marc Moghbel, Aline Roth, Daniela Baptista, Kapka Miteva, Fabienne Burger, Fabrizio Montecucco, Nicolas Vuilleumier, François Mach, Karim J Brandt

Journal: Res Pract Thromb Haemost

PubMed ID: 36304483

Doi: 10.1002/rth2.12828

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Blocking Autophagy in M1 Macrophages Enhances Virus Replication and Eye Disease in Ocularly Infected Transgenic Mice

Authors: Ujjaldeep Jaggi, Harry H Matundan, Dhong Hyun Lee, Homayon Ghiasi

Journal: J Virol

PubMed ID: 36286481

Doi: 10.1128/jvi.01401-22

Products & Services: Mammalian Expression

Apigenin suppresses mycoplasma-induced alveolar macrophages necroptosis via enhancing the methylation of TNF-α promoter by PPARγ-Uhrf1 axis

Authors: Xiuzhen Mei, Jian Wang, Chao Zhang, Jiale Zhu, Beibei Liu, Qingyun Xie, Ting Yuan, Yuzi Wu, Rong Chen, Xing Xie, Yanna Wei, Li Wang, Guoqing Shao, Qiyan Xiong, Yefen Xu, Zhixin Feng, Zhenzhen Zhang

Journal: Phytomedicine

PubMed ID: 36332388

Doi: 10.1016/j.phymed.2022.154504

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Combining mass spectrometry and machine learning to discover bioactive peptides

Authors: Christian T Madsen, Jan C Refsgaard, Felix G Teufel, Sonny K Kjærulff, Zhe Wang, Guangjun Meng, Carsten Jessen, Petteri Heljo, Qunfeng Jiang, Xin Zhao, Bo Wu, Xueping Zhou, Yang Tang, Jacob F Jeppesen, Christian D Kelstrup, Stephen T Buckley, Søren Tullin, Jan Nygaard-Jensen, Xiaoli Chen, Fang Zhang, Jesper V Olsen, Dan Han, Mads Grønborg, Ulrik de Lichtenberg

Journal: Nat Commun

PubMed ID: 36266275

Doi: 10.1038/s41467-022-34031-z

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Functional EGF domain of the human neuregulin 1α produced in Escherichia coli with accurate disulfide bonds

Authors: Arthur Schveitzer Ferreira, Amanda Lopacinski, Michel Batista, Priscila Mazzocchi Hiraiwa, Natalia Fernanda Bueno, Beatriz Gomes Guimarães, Nilson I T Zanchin

Journal: Mol Biol Rep

PubMed ID: 36198848

Doi: 10.1007/s11033-022-07956-3

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The Antimicrobial Peptide LJ-hep2 from Exerting Activities against Multiple Pathogenic Bacteria and Immune Protection In Vivo

Authors: Ruihao Gong, Zhe An, Weibin Zhang, Fangyi Chen, Ke-Jian Wang

Journal: Mar Drugs

PubMed ID: 36286474

Doi: 10.3390/md20100651

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Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation

Authors: Yoshibumi Ueda, Yuri Miura, Nario Tomishige, Naotoshi Sugimoto, Megumi Murase, Genki Kawamura, Norihiko Sasaki, Toshiyuki Ishiwata, Takeaki Ozawa

Journal: Cell Chem Biol

PubMed ID: 36288730

Doi: 10.1016/j.chembiol.2022.10.002

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Inhibition of intermittent calcium-activated potassium channel (SK4) attenuates Ang II-induced hypertrophy of human-induced stem cell-derived cardiomyocytes via targeting Ras-Raf-MEK1/2-ERK1/2 and CN-NFAT signaling pathways

Authors: Hongyi Zhao, Xi Wang, Yanhong Tang, Qingyan Zhao, Congxin Huang

Journal: Cell Biol Int

PubMed ID: 36273427

Doi: 10.1002/cbin.11948

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Engineering Self-Assembled Endolysin Nanoparticles against Antibiotic-Resistant Bacteria

Authors: Christian K O Dzuvor, Bhuvana K Shanbhag, Tayyaba Younas, Hsin-Hui Shen, Victoria S Haritos, Lizhong He

Journal: ACS Appl Bio Mater

PubMed ID: 36194892

Doi: 10.1021/acsabm.2c00741

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Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains

Authors: Xingxing Chen, Yize Sun, Laiqiang Chen, Xiu-Sheng Chen, Mingtian Pan, Yiran Zhang, Qi Wang, Weili Yang, Peng Yin, Dajian He, Xiangyu Guo, Su Yang, Yan Zeng, Sen Yan, Xiao-Jiang Li, Shihua Li

Journal: Cell Mol Life Sci

PubMed ID: 36251080

Doi: 10.1007/s00018-022-04577-8

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Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose)

Authors: Jijin R A Kuttiyatveetil, Heddy Soufari, Morgan Dasovich, Isabel R Uribe, Manija Mirhasan, Shang-Jung Cheng, Anthony K L Leung, John M Pascal

Journal: Cell Rep

PubMed ID: 36288691

Doi: 10.1016/j.celrep.2022.111529

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Multiplex Detection of Antibody Landscapes to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/Influenza/Common Human Coronaviruses Following Vaccination or Infection With SARS-CoV-2 and Influenza

Authors: Zhu Nan Li, Feng Liu, Stacie Jefferson, Lauren Horner, Paul Carney, Michael D L Johnson, Jennifer P King, Emily T Martin, Richard K Zimmerman, Karen Wernli, Manjusha Gaglani, Mark Thompson, Brendan Flannery, James Stevens, Terrence Tumpey, Min Z Levine

Journal: Clin Infect Dis

PubMed ID: 35684961

Doi: 10.1093/cid/ciac472

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The choroid plexus: a door between the blood and the brain for tissue-type plasminogen activator

Authors: Vincent Zuba, Jonathane Furon, Mathys Bellemain-Sagnard, Sara Martinez de Lizarrondo, Laurent Lebouvier, Marina Rubio, Yannick Hommet, Maxime Gauberti, Denis Vivien, Carine Ali

Journal: Fluids Barriers CNS

PubMed ID: 36243724

Doi: 10.1186/s12987-022-00378-0

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Multiple phage resistance systems inhibit infection via SIR2-dependent NAD⁺ depletion

Authors: Jeremy Garb, Anna Lopatina, Aude Bernheim, Mindaugas Zaremba, Virginijus Siksnys, Sarah Melamed, Azita Leavitt, Adi Millman, Gil Amitai, Rotem Sorek

Journal: Nat Microbiol

PubMed ID: 36192536

Doi: 10.1038/s41564-022-01207-8

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Comprehensive transcription terminator atlas for Bacillus subtilis

Authors: Zachary F Mandell, Rishi K Vishwakarma, Helen Yakhnin, Katsuhiko S Murakami, Mikhail Kashlev, Paul Babitzke

Journal: Nat Microbiol

PubMed ID: 36192538

Doi: 10.1038/s41564-022-01240-7

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Immunogenicity of SARS-CoV-2 spike antigens derived from Beta & Delta variants of concern

Authors: Bassel Akache, Tyler M Renner, Matthew Stuible, Nazanin Rohani, Yuneivy Cepero-Donates, Lise Deschatelets, Renu Dudani, Blair A Harrison, Christian Gervais, Jennifer J Hill, Usha D Hemraz, Edmond Lam, Sophie Régnier, Anne E G Lenferink, Yves Durocher, Michael J McCluskie

Journal: npj Vaccines

PubMed ID: 36224247

Doi: 10.1038/s41541-022-00540-7

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Core-Shell Structured Chitosan-Polyethylenimine Nanoparticles for Gene Delivery: Improved Stability, Cellular Uptake, and Transfection Efficiency

Authors: Jens Casper, Laura Nicolle, Melanie Willimann, Evrim Ümit Kuzucu, Alan Tran, Perrine Robin, Pascal Detampel, Hiu Man Grisch-Chan, Beat Thöny, Jörg Huwyler, Sandrine Gerber-Lemaire

Journal: Macromol Biosci

PubMed ID: 36200651

Doi: 10.1002/mabi.202200314

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Dengue virus downregulates TNFR1- and TLR3-stimulated NF-κB activation by targeting RIPK1

Authors: Darshika J Udawatte, Diane M Lang, Jeffrey R Currier, Carey L Medin, Alan L Rothman

Journal: Front Cell Infect Microbiol

PubMed ID: 36310878

Doi: 10.3389/fcimb.2022.926036

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Clinical, Virologic, and Immunologic Evaluation of Symptomatic Coronavirus Disease 2019 Rebound Following Nirmatrelvir/Ritonavir Treatment

Authors: Brian P Epling, Joseph M Rocco, Kristin L Boswell, Elizabeth Laidlaw, Frances Galindo, Anela Kellogg, Sanchita Das, Allison Roder, Elodie Ghedin, Allie Kreitman, Robin L Dewar, Sophie E M Kelly, Heather Kalish, Tauseef Rehman, Jeroen Highbarger, Adam Rupert, Gregory Kocher, Michael R Holbrook, Andrea Lisco, Maura Manion, Richard A Koup, Irini Sereti

Journal: Clin Infect Dis

PubMed ID: 36200701

Doi: 10.1093/cid/ciac663

Isolation of a Peptide That Binds to Lytic Bacteriophage

Authors: Soo Khim Chan, Zhongchao Zhao, Samuel Penziner, Ethan Khong, David Pride, Robert T Schooley, Nicole F Steinmetz

Journal: ACS Omega

PubMed ID: 36312416

Doi: 10.1021/acsomega.2c05539

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A tunable metabolic valve for precise growth control and increased product formation in Pseudomonas putida

Authors: Christos Batianis, Rik P van Rosmalen, Monika Major, Cheyenne van Ee, Alexandros Kasiotakis, Ruud A Weusthuis, Vitor A P Martins Dos Santos

Journal: Metab Eng

PubMed ID: 36244546

Doi: 10.1016/j.ymben.2022.10.002

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A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer

Authors: Kristin A Altwegg, Suryavathi Viswanadhapalli, Monica Mann, Dimple Chakravarty, Samaya Krishnan, Zexuan Liu, Junhao Liu, Uday P Pratap, Behnam Ebrahimi, John R Sanchez, Xiaonan Li, Shihong Ma, Ben H Park, Bindu Santhamma, Yidong Chen, Zhao Lai, Ganesh V Raj, Yaxia Yuan, Daohong Zhou, Gangadhara R Sareddy, Rajeshwar R Tekmal, Stan McHardy, Tim H-M Huang, Manjeet K Rao, Hariprasad Vankayalapati, Ratna K Vadlamudi

Journal: Cancer Res

PubMed ID: 35950923

Doi: 10.1158/0008-5472.CAN-22-0698

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Fluorescence dequenching assay for the activity of TEV protease

Authors: Chathura Paththamperuma, Richard C Page

Journal: Anal Biochem

PubMed ID: 36265691

Doi: 10.1016/j.ab.2022.114954

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Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition

Authors: Wei-Hung Chen, JungHyun Kim, Wei Bu, Nathan L Board, Yaroslav Tsybovsky, Yanmei Wang, Anna Hostal, Sarah F Andrews, Rebecca A Gillespie, Misook Choe, Tyler Stephens, Eun Sung Yang, Amarendra Pegu, Caroline E Peterson, Brian E Fisher, John R Mascola, Stefania Pittaluga, Adrian B McDermott, Masaru Kanekiyo, M Gordon Joyce, Jeffrey I Cohen

Journal: Immunity

PubMed ID: 36306784

Doi: 10.1016/j.immuni.2022.10.003

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BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway

Authors: Tianxiang Li, Zhirong Geng, Ju Zhang, Lu Xu, Xiaoli Zhu

Journal: Free Radic Biol Med

PubMed ID: 36272670

Doi: 10.1016/j.freeradbiomed.2022.10.299

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Efficacy and safety of universal (TCRKO) ARI-0001 CAR-T cells for the treatment of B-cell lymphoma

Authors: Noelia Maldonado-Pérez, María Tristán-Manzano, Pedro Justicia-Lirio, Elena Martínez-Planes, Pilar Muñoz, Kristina Pavlovic, Marina Cortijo-Gutiérrez, Carlos Blanco-Benítez, María Castella, Manel Juan, Mathias Wenes, Pedro Romero, Francisco J Molina-Estévez, Concepción Marañón, Concha Herrera, Karim Benabdellah, Francisco Martin

Journal: Front Immunol

PubMed ID: 36275777

Doi: 10.3389/fimmu.2022.1011858

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Reverse genetics based H5N2 vaccine provides clinical protection against H5N1, H5N8 and H9N2 avian influenza infection in chickens

Authors: Sivasankar Panickan, Sandeep Bhatia, Sushant Bhat, Nisha Bhandari, Atul Kumar Pateriya, Semmannan Kalaiyarasu, Richa Sood, Meghna Tripathi

Journal: Vaccine

PubMed ID: 36374710

Doi: 10.1016/j.vaccine.2022.10.018

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Investigating the Role of African Horse Sickness Virus VP7 Protein Crystalline Particles on Virus Replication and Release

Authors: Shani Bekker, Christiaan A Potgieter, Vida van Staden, Jacques Theron

Journal: Viruses

PubMed ID: 36298748

Doi: 10.3390/v14102193

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Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins

Authors: Michael D Healy, Joanna Sacharz, Kerrie E McNally, Calum McConville, Vikas A Tillu, Ryan J Hall, Molly Chilton, Peter J Cullen, Mehdi Mobli, Rajesh Ghai, David A Stroud, Brett M Collins

Journal: Structure

PubMed ID: 36302387

Doi: 10.1016/j.str.2022.10.001

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Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant

Authors: Wei Zhang, Ke Shi, Qibin Geng, Gang Ye, Hideki Aihara, Fang Li

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36256797

Doi: 10.1073/pnas.2206509119

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Structural basis for product specificities of MLL family methyltransferases

Authors: Yanjing Li , Lijie Zhao , Yuebin Zhang , Ping Wu , Ying Xu , Jun Mencius , Yongxin Zheng , Xiaoman Wang , Wancheng Xu , Naizhe Huang , Xianwen Ye , Ming Lei , Pan Shi , Changlin Tian , Chao Peng , Guohui Li , Zhijun Liu , Shu Quan , Yong Chen

Journal: Mol Cell

PubMed ID: 36108631

Doi: 10.1016/j.molcel.2022.08.022

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Advanced pathway engineering for phototrophic putrescine production

Authors: Robert A Freudenberg , Luisa Wittemeier , Alexander Einhaus , Thomas Baier , Olaf Kruse

Journal: Plant Biotechnol J

PubMed ID: 35748533

Doi: 10.1111/pbi.13879

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Human melanocortin-2 receptor: Identifying a role for residues in the TM4, EC2, and TM5 domains in activation and trafficking as a result of co-expression with the accessory protein, Mrap1 in Chinese Hamster Ovary Cells.

Authors: Perry V Davis , Ciaran A Shaughnessy , Robert M Dores

Journal: Biomolecules

PubMed ID: 36291631

Doi: 10.3390/biom12101422

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Labeling Ebola Virus with a Self-Splicing Fluorescent Reporter

Authors: Baylee Heiden , Elke Mühlberger , Christopher W Lennon , Adam J Hume

Journal: Microorganisms

PubMed ID: 36363701

Doi: 10.3390/microorganisms10112110

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Crystal structure of an L-type lectin domain from archaea

Authors: Farha Khan, Kaza Suguna

Journal: Proteins

PubMed ID: 36301308

Doi: 10.1002/prot.26440

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Authors: Eyby Leon, Claris Nde, Randall S Ray, Diego Preciado, Irene E Zohn

Journal: Am J Med Genet A

PubMed ID: 36263470

Doi: 10.1002/ajmg.a.62991

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Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2

Authors: Phillip Pymm, Samuel J Redmond, Olan Dolezal, Francesca Mordant, Ester Lopez, James P Cooney, Kathryn C Davidson, Ebene R Haycroft, Chee Wah Tan, Rebecca Seneviratna, Samantha L Grimley, Damian F J Purcell, Stephen J Kent, Adam K Wheatley, Lin-Fa Wang, Andrew Leis, Alisa Glukhova, Marc Pellegrini, Amy W Chung, Kanta Subbarao, Adam P Uldrich, Wai-Hong Tham, Dale I Godfrey, Nicholas A Gherardin

Journal: iScience

PubMed ID: 36213007

Doi: 10.1016/j.isci.2022.105259

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SARS-CoV-2 Transmission from Human to Pet and Suspected Transmission from Pet to Human, Thailand

Authors: Chutchai Piewbang, Panida Poonsin, Pattiya Lohavicharn, Sabrina Wahyu Wardhani, Wichan Dankaona, Jiratchaya Puenpa, Yong Poovorawan, Somporn Techangamsuwan

Journal: J Clin Microbiol

PubMed ID: 36314788

Doi: 10.1128/jcm.01058-22

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Divergent SARS-CoV-2-specific T cell responses in intensive care unit workers following mRNA COVID-19 vaccination

Authors: Estefanía Salgado Del Riego, María Laura Saiz, Viviana Corte-Iglesias, Blanca Leoz Gordillo, Cristina Martin-Martin, Mercedes Rodríguez-Pérez, Dolores Escudero, Carlos Lopez-Larrea, Beatriz Suarez-Alvarez

Journal: Front Immunol

PubMed ID: 36275696

Doi: 10.3389/fimmu.2022.942192

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The Therapeutic Effects of a PEDF-Derived Short Peptide on Murine Experimental Dry Eye Involves Suppression of MMP-9 and Inflammation

Authors: Tsung-Chuan Ho, Nai-Wen Fan, Shu-I Yeh, Show-Li Chen, Yeou-Ping Tsao

Journal: Transl Vis Sci Technol

PubMed ID: 36201200

Doi: 10.1167/tvst.11.10.12

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Antibody Response to Rotavirus C Pre-Farrow Natural Planned Exposure to Gilts and Their Piglets

Authors: Deepak Kumar, Amanda V Anderson, Jeremy Pittman, Nora L Springer, Douglas G Marthaler, Waithaka Mwangi

Journal: Viruses

PubMed ID: 36298806

Doi: 10.3390/v14102250

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Deciphering the Key Regulatory Roles of KLF6 and Bta-miR-148a on Milk Fat Metabolism in Bovine Mammary Epithelial Cells

Authors: Ambreen Iqbal, Haibin Yu, Ping Jiang, Zhihui Zhao

Journal: Genes (Basel)

PubMed ID: 36292712

Doi: 10.3390/genes13101828

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Focused B cell response to recurring gluten motif with implications for epitope spreading in celiac disease

Authors: Chunyan Zhou, Thomas Østerbye, Emil Bach, Shiva Dahal-Koirala, Lene S Høydahl, Øyvind Steinsbø, Jørgen Jahnsen, Knut E A Lundin, Søren Buus, Ludvig M Sollid, Rasmus Iversen

Journal: Cell Rep

PubMed ID: 36288703

Doi: 10.1016/j.celrep.2022.111541

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Single-cell RNA sequencing analysis of shrimp immune cells identifies macrophage-like phagocytes

Authors: Peng Yang , Yaohui Chen , Zhiqi Huang , Huidan Xia , Ling Cheng , Hao Wu , Yueling Zhang , Fan Wang

Journal: Elife

PubMed ID: 36200862

Doi: 10.7554/eLife.80127

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Intracellular infection by symbiotic bacteria requires the mitotic kinase AURORA1

Authors: Jin-Peng Gao , Suyu Jiang , Yangyang Su , Ping Xu , Junjie Wang , Wenjie Liang , Cheng-Wu Liu , Jeremy D Murray