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MiR-130b modulates the invasive, migratory, and metastatic behavior of leiomyosarcoma

Authors: Laura S Danielson, Maria V Guijarro, Silvia Menendez, Brett Higgins, Qiang Sun, Khushbakhat Mittal, Dorota A Popiolek, Michael Overholtzer, Glyn D Palmer, Eva Hernando

Journal: PLoS ONE

PubMed ID: 36701370

Doi: 10.1371/journal.pone.0278844

Products & Services: Molecular Biology Reagents

Differentially Expressed Genes and Signalling Pathways Regulated by High Selenium Involved in Antioxidant and Immune Functions of Goats Based on Transcriptome Sequencing

Authors: Xu Wang, Chao Ban, Jia-Xuan Li, Qing-Yuan Luo, Ji-Xiao Qin, Yi-Qing Xu, Qi Lu, Xing-Zhou Tian

Journal: Int J Mol Sci

PubMed ID: 36674636

Doi: 10.3390/ijms24021124

Products & Services: Molecular Biology Reagents

Ligand-dependent protein interactions of the juvenile hormone receptor captured in real time

Authors: Sarka Tumova, Marek Jindra

Journal: FEBS J

PubMed ID: 36609881

Doi: 10.1111/febs.16719

Products & Services: Molecular Biology Reagents

Discovery and validation of new Hv1 proton channel inhibitors with onco-therapeutic potential

Authors: Antoun El Chemaly, Vincent Jaquet, Yves Cambet, Aurélie Caillon, Ophélie Cherpin, Alexia Balafa, Karl-Heinz Krause, Nicolas Demaurex

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 36640925

Doi: 10.1016/j.bbamcr.2022.119415

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His-tagged lactate oxidase production for industrial applications using fed-batch fermentation

Authors: Agustina Godino, Marilla Amaranto, Agustina Manassero, Fausto Comba, Martín Alonzo Pérez, Lucio Simonella, Martín Pernigotti, José L Barra

Journal: J Biotechnol

PubMed ID: 36608873

Doi: 10.1016/j.jbiotec.2022.12.011

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Protective Effects of against High-Cholesterol Diet-Induced Fatty Liver and Regulation of Host Gene Expression Profiles

Authors: Tianhua He, Nikita Lykov, Xu Luo, Huiling Wang, Zhanxiang Du, Ziyi Chen, Shitian Chen, Lin Zhu, Ye Zhao, Chimeng Tzeng

Journal: Int J Mol Sci

PubMed ID: 36768377

Doi: 10.3390/ijms24032053

Products & Services: Proteins, Expression, Isolation and Analysis

Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation

Authors: Pedro Madrigal, Siwei Deng, Yuliang Feng, Stefania Militi, Kim Jee Goh, Reshma Nibhani, Rodrigo Grandy, Anna Osnato, Daniel Ortmann, Stephanie Brown, Siim Pauklin

Journal: Nat Commun

PubMed ID: 36697417

Doi: 10.1038/s41467-023-36116-9

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Hyaluronate decorated polyethylene glycol linked poly(lactide-co-glycolide) nanoparticles encapsulating MUC-1 peptide augmented mucosal immune response in Balb/c mice through inhalation route

Authors: Kiran Jyoti, Garima Malik, Monika Chaudhary, Jitender Madan, Anjoo Kamboj

Journal: Biochim Biophys Acta Gen Subj

PubMed ID: 36731729

Doi: 10.1016/j.bbagen.2023.130317

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Activity-balanced GLP-1/GDF15 dual agonist reduces body weight and metabolic disorder in mice and non-human primates

Authors: Yuanyuan Zhang, Xinyu Zhao, Xiaona Dong, Yuying Zhang, Haixia Zou, Yaoguang Jin, Wei Guo, Peng Zhai, Xu Chen, Alexei Kharitonenkov

Journal: Cell Metab

PubMed ID: 36706758

Doi: 10.1016/j.cmet.2023.01.001

Products & Services: Proteins, Expression, Isolation and Analysis

Comparative analysis of allergenicity and predicted linear epitopes in α and β parvalbumin from turbot (Scophthalmus maximus)

Authors: Yuhao Huang, Zhenxing Li, Yeting Wu, Yonghong Li, Siddanakoppalu Pramod, Guanzhi Chen, Wenjia Zhu, Ziye Zhang, Hao Wang, Hong Lin

Journal: J Sci Food Agric

PubMed ID: 36606403

Doi: 10.1002/jsfa.12432

Products & Services: Proteins, Expression, Isolation and Analysis

Oncogenic KRAS signaling drives evasion of innate immune surveillance in lung adenocarcinoma by activating CD47

Authors: Huanhuan Hu, Rongjie Cheng, Yanbo Wang, Xiaojun Wang, Jianzhuang Wu, Yan Kong, Shoubin Zhan, Zhen Zhou, Hongyu Zhu, Ranran Yu, Gaoli Liang, Qingyan Wang, Xiaoju Zhu, Chen-Yu Zhang, Rong Yin, Chao Yan , Xi Chen

Journal: The Journal of Clinical Investigation

PubMed ID: 36413402

Doi: 10.1172/JCI153470

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Cytochalasin B-Induced Membrane Vesicles from TRAIL-Overexpressing Mesenchymal Stem Cells Induce Extrinsic Pathway of Apoptosis in Breast Cancer Mouse Model

Authors: Daria S Chulpanova , Tamara V Pukhalskaia , Zarema E Gilazieva , Yuliya V Filina 1, Milana N Mansurova 1, Albert A Rizvanov 1, Valeriya V Solovyeva

Journal: Curr Issues Mol Biol .

PubMed ID: 36661524

Doi: 10.3390/cimb45010038

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α-Synuclein as a Target for Metallo-Anti-Neurodegenerative Agents

Authors: Kaiming Cao , Yang Zhu , Zhuanghao Hou , Manman Liu , Yanyan Yang , Hongze Hu , Yi Dai , Yu Wang , Siming Yuan , Guangming Huang , Jiaming Mei , Peter J Sadler , Yangzhong Liu

Journal: Angew Chem Int Ed Engl .

PubMed ID: 36345707

Doi: 10.1002/anie.202215360

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Click and bioorthogonal hyaluronic acid hydrogels as an ultra-tunable platform for the investigation of cell-material interactions

Authors: Nathan Lagneau, Pierre Tournier, Boris Halgand, François Loll, Yves Maugars, Jérôme Guicheux, Catherine Le Visage, Vianney Delplace

Journal: Bioact Mater

PubMed ID: 36632500

Doi: 10.1016/j.bioactmat.2022.12.022

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The establishment of multiple knockout mutants of Colletotrichum orbiculare by CRISPR-Cas9 and Cre-loxP systems

Authors: Kohji Yamada, Toya Yamamoto, Kanon Uwasa, Keishi Osakabe, Yoshitaka Takano

Journal: Fungal Genet Biol

PubMed ID: 36669556

Doi: 10.1016/j.fgb.2023.103777

Products & Services: Proteins, Expression, Isolation and Analysis

Association Between Human Immunodeficiency Virus Viremia and Compromised Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant

Authors: Shi-Hsia Hwa, Jumari Snyman, Mallory Bernstein, Yashica Ganga, Sandile Cele, Daniel Muema, Chee Wah Tan, Khadija Khan, Farina Karim, Willem Hanekom, Leslie Bernstein, Stefan H E Kaufmann, Lin-Fa Wang, Thumbi Ndung'u, Alex Sigal

Journal: J Infect Dis

PubMed ID: 35975942

Doi: 10.1093/infdis/jiac343

Products & Services: Proteins, Expression, Isolation and Analysis

The NOTCH-RIPK4-IRF6-ELOVL4 Axis Suppresses Squamous Cell Carcinoma

Authors: Yue Yan, Marc-Andre Gauthier, Ahmad Malik, Iosifina Fotiadou, Michael Ostrovski, Dzana Dervovic, Logine Ghadban, Ricky Tsai, Gerald Gish, Sampath Kumar Loganathan, Daniel Schramek

Journal: Cancers (Basel)

PubMed ID: 36765696

Doi: 10.3390/cancers15030737

Products & Services: Proteins, Expression, Isolation and Analysis

SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression

Authors: Laura Cioetto-Mazzabò, Francesca Boldrin, Claire Beauvineau, Martin Speth, Alberto Marina, Amine Namouchi, Greta Segafreddo, Mena Cimino, Sandrine Favre-Rochex, Seetha Balasingham, Beatriz Trastoy, Hélène Munier-Lehmann, Gareth Griffiths, Brigitte Gicquel, Marcelo E Guerin, Riccardo Manganelli, Noelia Alonso-Rodríguez

Journal: Nucleic Acids Res

PubMed ID: 36546765

Doi: 10.1093/nar/gkac1173

Products & Services: Proteins, Expression, Isolation and Analysis

The FACT-targeted drug CBL0137 enhances the effects of rituximab to inhibit B-cell non-Hodgkin's lymphoma tumor growth by promoting apoptosis and autophagy

Authors: Yan Lv, Yuxin Du, Kening Li, Xiao Ma, Juan Wang, Tongde Du, Yuxin Ma, Yue Teng, Weiyan Tang, Rong Ma, Jianqiu Wu, Jianzhong Wu, Jifeng Feng

Journal: Cell Commun Signal

PubMed ID: 36691066

Doi: 10.1186/s12964-022-01031-x

Products & Services: Proteins, Expression, Isolation and Analysis

Plant production of a virus-like particle-based vaccine candidate against porcine reproductive and respiratory syndrome

Authors: Jordan T VanderBurgt, Ondre Harper, Christopher P Garnham, Susanne E Kohalmi, Rima Menassa

Journal: Front Plant Sci

PubMed ID: 36760639

Doi: 10.3389/fpls.2023.1044675

Products & Services: Proteins, Expression, Isolation and Analysis

Generation of Gαi knock-out HEK293 cells illuminates Gαi-coupling diversity of GPCRs

Authors: Yuki Ono, Kouki Kawakami, Gaku Nakamura, Satoru Ishida, Junken Aoki, Asuka Inoue

Journal: Commun Biol

PubMed ID: 36709222

Doi: 10.1038/s42003-023-04465-2

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Genomewide Association Study Identifies Copy Number Variants Associated With Warfarin Dose Response and Risk of Venous Thromboembolism in African Americans

Authors: Honghong Zhang, Cristina Alarcon, Larisa H Cavallari, Edith Nutescu, Gemma L Carvill, Minoli A Perera, Wenndy Hernandez

Journal: Clin Pharmacol Ther

PubMed ID: 36507737

Doi: 10.1002/cpt.2820

Products & Services: Molecular Biology Reagents

Spike-mediated viral membrane fusion is inhibited by a specific anti-IFITM2 monoclonal antibody

Authors: Anna Basile , Carla Zannella , Margot De Marco , Giuseppina Sanna , Gianluigi Franci , Massimiliano Galdiero , Aldo Manzin , Vincenzo De Laurenzi , Massimiliano Chetta , Alessandra Rosati , Maria Caterina Turco , Liberato Marzullo

Journal: Antiviral Res

PubMed ID: 36669656

Doi: 10.1016/j.antiviral.2023.105546

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Identification of B-Cell Epitopes on Capsid Protein Reveals Two Potential Neutralization Mechanisms in Red-Spotted Grouper Nervous Necrosis Virus

Authors: Zhiqi Zhang, Jing Xing, Xiaoqian Tang, Xiuzhen Sheng, Heng Chi, Wenbin Zhan

Journal: J Virol

PubMed ID: 36633407

Doi: 10.1128/jvi.01748-22

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Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy

Authors: Justin M Quiles, Rita H Najor, Eileen Gonzalez, Monica Jeung, Wenjing Liang, Sarah M Burbach, Erika A Zumaya, Rachel Y Diao, Mark A Lampert, Åsa B Gustafsson

Journal: Sci Signal

PubMed ID: 36719945

Doi: 10.1126/scisignal.abo4457

Products & Services: Proteins, Expression, Isolation and Analysis

B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV

Authors: Jacopo Polvere, Massimiliano Fabbiani, Gabiria Pastore, Ilaria Rancan, Barbara Rossetti, Miriam Durante, Sara Zirpoli, Enrico Morelli, Elena Pettini, Simone Lucchesi, Fabio Fiorino, Mario Tumbarello, Annalisa Ciabattini, Francesca Montagnani, Donata Medaglini

Journal: Commun Med (Lond)

PubMed ID: 36717688

Doi: 10.1038/s43856-023-00245-5

Products & Services: Molecular Biology Reagents

Identification of a Novel Interaction between Prohibitin (PHB-1) and Bovine RuvB-Like AAA ATPase 1

Authors: Prasanna Babu Araveti, Prajna Parimita Kar, Akshay Kuriakose, Achintya Sanju, Kota Arun Kumar, Anand Srivastava

Journal: Microbiol Spectr

PubMed ID: 36651733

Doi: 10.1128/spectrum.02502-22

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The NLRP6 protein is very faintly expressed in several normal and cancerous epithelial cells and may be confused with an unrelated protein

Authors: Abdallah Mound, Gautier Goormachtigh, Fabrice Bray, Stéphanie Flament, Christian Rolando, Richard Ruez, Nathalie Martin, Amélie Decourcelle, Vanessa Dehennaut, Jean-Michel Saliou, Mathias Chamaillard, Corinne Abbadie

Journal: PLoS ONE

PubMed ID: 36662875

Doi: 10.1371/journal.pone.0279028

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Functions of human olfactory mucus and age-dependent changes

Authors: Tomohiro Shirai, Dan Takase, Junkichi Yokoyama, Kuniyuki Nakanishi, Chisaki Uehara, Naoko Saito, Aya Kato-Namba, Keiichi Yoshikawa

Journal: Sci Rep

PubMed ID: 36653421

Doi: 10.1038/s41598-023-27937-1

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Unusual crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing in antigen presentation

Authors: Lenong Li, Xubiao Peng, Mansoor Batliwala, Marlene Bouvier

Journal: Res Sq

PubMed ID: 36747752

Doi: 10.21203/rs.3.rs-2500847/v1

Products & Services: Proteins, Expression, Isolation and Analysis

Comprehensive Comparison of Seven SARS-CoV-2-Specific Surrogate Virus Neutralization and Anti-Spike IgG Antibody Assays Using a Live-Virus Neutralization Assay as a Reference

Authors: Marianne Graninger, Claudia Maria Jani, Elisabeth Reuberger, Katja Prüger, Philipp Gaspar, David Niklas Springer, Christian Borsodi, Lisa Weidner, Susanne Rabady, Elisabeth Puchhammer-Stöckl, Christof Jungbauer, Eva Höltl, Judith Helene Aberle, Karin Stiasny, Lukas Weseslindtner

Journal: Microbiol Spectr

PubMed ID: 36622205

Doi: 10.1128/spectrum.02314-22

Products & Services: Proteins, Expression, Isolation and Analysis

Investigating the Sequence Specific Adsorption Behavior of Polypeptides at the Solid/Liquid Interface

Authors: Christopher S O'Bryan, Timothy J Murdoch, Daniel J Strickland, Katie A Rose, Denis Bendejacq, Daeyeon Lee, Russell J Composto

Journal: Langmuir

PubMed ID: 36637895

Doi: 10.1021/acs.langmuir.2c02292

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Vimentin epigenetic deregulation in Bladder Cancer associates with acquisition of invasive and metastatic phenotype through epithelial-to-mesenchymal transition

Authors: Sara Monteiro-Reis, Vera Miranda-Gonçalves, Catarina Guimarães-Teixeira, Cláudia Martins-Lima, João Lobo, Diana Montezuma, Paula C Dias, Helene Neyret-Kahn, Isabelle Bernard-Pierrot, Rui Henrique, Carmen Jerónimo

Journal: Int J Biol Sci

PubMed ID: 36594099

Doi: 10.7150/ijbs.77181

Products & Services: Proteins, Expression, Isolation and Analysis

Functional characterization of a novel aminoglycoside phosphotransferase, APH(9)-Ic, and its variant from

Authors: Weina Shi, Junwan Lu, Chunlin Feng, Mengdi Gao, Anqi Li, Shuang Liu, Lei Zhang, Xueya Zhang, Qiaoling Li, Hailong Lin, Xi Lin, Kewei Li, Hailin Zhang, Yunliang Hu, Guangli Wang, Qiyu Bao, Weiyan Jiang

Journal: Front Cell Infect Microbiol

PubMed ID: 36699730

Doi: 10.3389/fcimb.2022.1097561

Products & Services: Proteins, Expression, Isolation and Analysis

Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth

Authors: Hyukjun Choi, Mirae Yeo, Yujin Kang, Hyo Jeong Kim, Seong Guk Park, Eunjung Jang, Sung Ho Park, Eunhee Kim, Sebyung Kang

Journal: J Nanobiotechnology

PubMed ID: 36597089

Doi: 10.1186/s12951-022-01762-6

Products & Services: Proteins, Expression, Isolation and Analysis

A linear DNA encoding the SARS-CoV-2 receptor binding domain elicits potent immune response and neutralizing antibodies in domestic cats

Authors: Antonella Conforti, Elisa Sanchez, Erika Salvatori, Lucia Lione, Mirco Compagnone, Eleonora Pinto, Fabio Palombo, Emanuela D'Acunto, Alessia Muzi, Giuseppe Roscilli, Yuhua Sun, Brian Viscount, James Hayward, Clay Shorrock, Diego G Diel, Joseph A Impellizeri, Luigi Aurisicchio

Journal: Mol Ther Methods Clin Dev

PubMed ID: 36618106

Doi: 10.1016/j.omtm.2022.12.015

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AKT1 regulates UHRF1 protein stability and promotes the resistance to abiraterone in prostate cancer

Authors: Yongming Fu, Tuoyu Cao, Xiaorui Zou, Yubing Ye, Youhong Liu, Yuchong Peng, Tanggang Deng, Linglong Yin, Xiong Li

Journal: Oncogenesis

PubMed ID: 36593255

Doi: 10.1038/s41389-022-00446-y

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Cellular and humoral immunity to Ebola Zaire glycoprotein and viral vector proteins following immunization with recombinant vesicular stomatitis virus-based Ebola vaccine (rVSVΔG-ZEBOV-GP)

Authors: Vanessa Raabe, Lilin Lai, Juliet Morales, Yongxian Xu, Nadine Rouphael, Richard T Davey, Mark J Mulligan

Journal: Vaccine

PubMed ID: 36725433

Doi: 10.1016/j.vaccine.2023.01.059

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Design of a chimeric ACE-2/Fc-silent fusion protein with ultrahigh affinity and neutralizing capacity for SARS-CoV-2 variants

Authors: Neil M Bodie, Rina Hashimoto, David Connolly, Jennifer Chu, Kazuo Takayama, Bruce D Uhal

Journal: Antib Ther

PubMed ID: 36741194

Doi: 10.1093/abt/tbad001

Products & Services: Proteins, Expression, Isolation and Analysis

Cry51Aa Proteins Are Active against and Show a Mechanism Similar to Pore Formation Model

Authors: Ei Thinzar Soe, Zaw Lin Naing, Caihong Zhang, Lin Lin Niu, Jinrong Tang, Siqi Yu, Zhongwei Ding, Gemei Liang

Journal: J Agric Food Chem

PubMed ID: 36710440

Doi: 10.1021/acs.jafc.2c07244

Products & Services: Proteins, Expression, Isolation and Analysis

Simultaneous enzyme production, Levan-type FOS synthesis and sugar by-products elimination using a recombinant Pichia pastoris strain expressing a levansucrase-endolevanase fusion enzyme

Authors: Ángela Ávila-Fernández, Silvia Montiel, María Elena Rodríguez-Alegría, Luis Caspeta, Agustín López Munguía

Journal: Microb Cell Fact

PubMed ID: 36703199

Doi: 10.1186/s12934-022-02009-7

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Structure of monkeypox virus DNA polymerase holoenzyme

Authors: Qi Peng, Yufeng Xie, Lu Kuai, Han Wang, Jianxun Qi, George F Gao, Yi Shi

Journal: Science (New York, N. Y.)

PubMed ID: 36520947

Doi: 10.1126/science.ade6360

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Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis

Authors: Alhaji H. Janneh, Mohamed Faisal Kassir, F. Cansu Atilgan, Stephen Tomlinson, Shikhar Mehrotra, Besim Ogretmen

Journal: Cell Reports

Doi: doi.org/10.1016/j.celrep.2022.111742

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Structure-activity relationship studies for inhibitors for vancomycin-resistant and human carbonic anhydrases

Authors: Weiwei An, Katrina J Holly, Alessio Nocentini, Ryan D Imhoff, Chad S Hewitt, Nader S Abutaleb, Xufeng Cao, Mohamed N Seleem, Claudiu T Supuran, Daniel P Flaherty

Journal: J Enzyme Inhib Med Chem

PubMed ID: 35758212

Doi: 10.1080/14756366.2022.2092729

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Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A

Authors: Dell'Orco D, Dal Cortivo G.

Journal: Sci Rep

PubMed ID: 31882816

Doi: 10.1038/s41598-019-56606-5

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SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugate

Authors: Alexander J Garvin , Alexander J Lanz , Joanna R Morris

Journal: Sci Rep

PubMed ID: 36494414

Doi: 10.1038/s41598-022-25665-6

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Prevalence of Anti-PF4 Antibodies After First and Second ChAdOx1 nCoV-19 Vaccinations in Women With Adverse Events: A Brief Report and Literature Review

Authors: Kye Won Choe, Yong Kwan Lim, Oh Joo Kweon, Mi-Kyung Lee, Jin-Won Chung, Hye Ryoun Kim

Journal: Ann Lab Med

PubMed ID: 36544343

Doi: 10.3343/alm.2023.43.3.299

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of selective hepatitis delta virus ribozyme inhibitors by high-throughput screening of small molecule libraries

Authors: Eirini D Tseligka, Stéphanie Conzelmann, Yves Cambet, Tifany Schaer, Francesco Negro, Sophie Clément

Journal: JHEP Rep

PubMed ID: 36704052

Doi: 10.1016/j.jhepr.2022.100652

Products & Services: Proteins, Expression, Isolation and Analysis

Influence of affinity tags and tobacco PR1a signal peptide on detection, purification and bioactivity analyses of the small oomycete apoplastic effectors

Authors: Jing-Hao Jin, Xue Zhou, Wang Liu, Zi-Hui Zhang, Shen-Xin Huang, Wen-Jing Zhao, Xiao-Ren Chen

Journal: Biotechnol Lett

PubMed ID: 36450976

Doi: 10.1007/s10529-022-03324-0

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Development of a cockroach (Blattella germanica) qPCR for the objective measurement of exposure at home

Authors: Steffi Rocchi, Benoit Valot, Audrey Laboissière, Audrey Guitton, Emeline Scherer, Laurence Millon, Gabriel Reboux

Journal: Sci Total Environ

PubMed ID: 36526200

Doi: 10.1016/j.scitotenv.2022.160965

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BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network

Authors: Xueqin Sun, Olaf Klingbeil, Bin Lu, Caizhi Wu, Carlos Ballon, Meng Ouyang, Xiaoli S Wu, Ying Jin, Yon Hwangbo, Yu-Han Huang, Tim D D Somerville, Kenneth Chang, Jung Park, Taemoon Chung, Scott K Lyons, Junwei Shi, Hannes Vogel, Michael Schulder, Christopher R Vakoc, Alea A Mills

Journal: Nature

PubMed ID: 36544023

Doi: 10.1038/s41586-022-05551-x

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Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA

Authors: Seow Neng Chan, Jun Wei Pek

Journal: EMBO Rep

PubMed ID: 36533631

Doi: 10.15252/embr.202154350

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The effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple

Authors: Runmin Che, Changhai Liu, Qi Wang, Wenyan Tu, Ping Wang, Chao Li, Xiaoqing Gong, Ke Mao, Hao Feng, Lili Huang, Pengmin Li, Fengwang Ma

Journal: Autophagy

PubMed ID: 36449354

Doi: 10.1080/15548627.2022.2153573

Products & Services: Proteins, Expression, Isolation and Analysis

Tissue replication and mucosal swab detection of Sosuga virus in Syrian hamsters in the absence of overt tissue pathology and clinical disease

Authors: Stephen R Welch, Jana M Ritter, Amy J Schuh, Sarah C Genzer, Teresa E Sorvillo, Jessica R Harmon, JoAnn D Coleman-McCray, Shilpi Jain, Punya Shrivastava-Ranjan, Josilene Nascimento Seixas, Lindsey B Estetter, Pamela S Fair, Jonathan S Towner, Joel M Montgomery, César G Albariño, Christina F Spiropoulou, Jessica R Spengler

Journal: Antiviral Res

PubMed ID: 36521633

Doi: 10.1016/j.antiviral.2022.105490

Products & Services: Proteins, Expression, Isolation and Analysis

Roles of the transcriptional regulators Fts1, YlNrg1, YlTup1, and YlSsn6 in the repression of the yeast-to-filament transition in the dimorphic yeast Yarrowia lipolytica

Authors: Yi-Sheng Mao, Jia-Wen Chen, Zhen-Hua Wang, Meng-Yang Xu, Xiang-Dong Gao

Journal: Mol Microbiol

PubMed ID: 36537557

Doi: 10.1111/mmi.15017

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Functional recovery of myocardial infarction by specific EBP-PR1P peptides bridging injectable cardiac extracellular matrix and vascular endothelial growth factor

Authors: Wenxuan Cao, Hong Zhang, Ning Zhou, Runxue Zhou, Xiaojing Zhang, Jia Yin, Jin Deng, Xiang Ao, Chunying Shi

Journal: J Biomed Mater Res A

PubMed ID: 36579729

Doi: 10.1002/jbm.a.37483

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Cadmium chloride exposure impairs the growth and behavior of Drosophila via ferroptosis

Authors: Yingxia Hu, Haijie Wu, Chenying Lu, Hanqing Xu, Boyang Li, Wanchun Guan, Mingjiang Wu, Yitian Gao, Haibin Tong

Journal: Sci Total Environ

PubMed ID: 36581278

Doi: 10.1016/j.scitotenv.2022.161183

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Polymyxin B neutralizes endotoxin and improves the quality of chicken semen during liquid storage

Authors: Ei Ei Win Maung, Pangda Sopha Sushadi, Atsushi Asano

Journal: Theriogenology

PubMed ID: 36577162

Doi: 10.1016/j.theriogenology.2022.12.027

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Electrical stimulation of piezoelectric BaTiO3 coated Ti6Al4V scaffolds promote antiinflammatory polarization of macrophage and bone repair via MAPK/JNK inhibition and OXPHOS activation

Authors: Hao Wu, Dong Hui, Zhen Tang, Yu Chen, Yichao Liu, Mo Wang, Xinghui Wei, Ning Wang, Shusen Bao, Dongmei Yu, Zhigang Wu, Zhenda Yang, Xiaokang Li, Zheng Guo, Lei Shi

Journal: Biomaterials

Doi: 10.1016/j.biomaterials.2022.121990

Products & Services: Proteins, Expression, Isolation and Analysis

mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

Authors: Clifford T H Hayashi , Yi Cao , Leor C Clark , Abhai K Tripathi , Fidel Zavala , Garima Dwivedi , James Knox , Mohamad-Gabriel Alameh , Paulo J C Lin , Ying K Tam , Drew Weissman , Nirbhay Kumar

Journal: NPJ Vaccines

PubMed ID: 36456563

Doi: 10.1038/s41541-022-00577-8

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DNA-protein cross-links between abasic DNA damage and mitochondrial transcription factor A (TFAM)

Authors: Wenyan Xu , Jin Tang , Linlin Zhao

Journal: Nucleic Acids Res

PubMed ID: 36583367

Doi: 10.1093/nar/gkac1214

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Principles of mitoribosomal small subunit assembly in eukaryotes

Authors: Nathan J Harper, Chloe Burnside, Sebastian Klinge

Journal: Nature

PubMed ID: 36482135

Doi: 10.1038/s41586-022-05621-0

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An epitope-directed selection strategy facilitating the identification of Frizzled receptor selective antibodies

Authors: Qiangqiang Ge, Maikun Teng, Xu Li, Qiong Guo, Yuyong Tao

Journal: Structure

PubMed ID: 36513066

Doi: 10.1016/j.str.2022.11.009

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Long-Term Adaptation to Galactose as a Sole Carbon Source Selects for Mutations Outside the Canonical GAL Pathway

Authors: Artemiza A Martínez, Andrew Conboy, Sean W Buskirk, Daniel A Marad, Gregory I Lang

Journal: J Mol Evol

PubMed ID: 36482210

Doi: 10.1007/s00239-022-10079-9

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LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway

Authors: Uttam Sharma, Manjit Kaur Rana, Karuna Singh, Aklank Jain

Journal: Biochem Pharmacol

PubMed ID: 36493845

Doi: 10.1016/j.bcp.2022.115372

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Antibody Response of Heterologous vs Homologous Messenger RNA Vaccine Boosters Against the Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant: Interim Results from the PRIBIVAC Study, a Randomized Clinical Trial

Authors: Xuan Ying Poh, Chee Wah Tan, I Russel Lee, Jean-Marc Chavatte, Siew-Wai Fong, Tessa Prince, Catherine Hartley, Aileen Y Y Yeoh, Suma Rao, Po Ying Chia, Sean W X Ong, Tau Hong Lee, Sapna P Sadarangani, Ray J H Lin, Clarissa Lim, Jefanie Teo, Daniel R X Lim, Wanni Chia, Julian A Hiscox, Lisa F P Ng, Ee Chee Ren, Raymond T P Lin, Laurent Renia, David Chien Lye, Lin-Fa Wang, Barnaby E Young

Journal: Clin Infect Dis

PubMed ID: 35543372

Doi: 10.1093/cid/ciac345

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Early TNF-Dependent Regulation of Excitatory and Inhibitory Synapses on Striatal Direct Pathway Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease

Authors: Julien Chambon, Pragya Komal, Gil M Lewitus, Gina M Kemp, Simone Valade, Houaria Adaïdi, Noura Al Bistami, David Stellwagen

Journal: J Neurosci

PubMed ID: 36517241

Doi: 10.1523/JNEUROSCI.1655-22.2022

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A BioBricks Metabolic Engineering Platform for the Biosynthesis of Anthracyclinones in Streptomyces coelicolor

Authors: Rongbin Wang , Jennifer Nguyen , Jacob Hecht , Nora Schwartz , Katelyn V Brown , Larissa V Ponomareva, Magdalena Niemczura , Dino van Dissel , Gilles P van Wezel , Jon S Thorson, Mikko Metsä-Ketelä , Khaled A Shaaban, S Eric Nybo

Journal: ACS Synth Biol

PubMed ID: 36378506

Doi: 10.1021/acssynbio.2c00498

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Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling

Authors: Bärbel Schröfelbauer, Patrick K Kimes, Paige Hauke, Charlotte E Reid, Kevin Shao, Sarah J Hill, Rafael Irizarry, William C Hahn

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36574667

Doi: 10.1073/pnas.2206751120

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Disease modification and symptom relief in osteoarthritis using a mutated GCP-2/CXCL6 chemokine

Authors: Sara Caxaria, Nikolaos Kouvatsos, Suzanne E Eldridge, Mario Alvarez-Fallas, Anne-Sophie Thorup, Daniela Cici, Aida Barawi, Ammaarah Arshed, Danielle Strachan, Giulia Carletti, Xinying Huang, Sabah Bharde, Melody Deniz, Jacob Wilson, Bethan L Thomas, Costantino Pitzalis, Francesco Paolo Cantatore, Manasi Sayilekshmy, Shafaq Sikandar, Frank P Luyten, Thomas Pap, Joanna C Sherwood, Anthony J Day, Francesco Dell'Accio

Journal: EMBO Mol Med

PubMed ID: 36507558

Doi: 10.15252/emmm.202216218

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Comment on: Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage

Authors: Luiza H Galarion, Justin E Clarke, Harry Schofield, Alex J O'Neill

Journal: J Antimicrob Chemother

PubMed ID: 36416794

Doi: 10.1093/jac/dkac397

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High-Throughput and Efficient Intracellular Delivery Method via a Vibration-Assisted Nanoneedle/Microfluidic Composite System

Authors: Xuan Li , Yuan Ma , Yu Xue , Xuanhe Zhang , Linwen Lv , Qianghua Quan , Yiqing Chen , Guoxu Yu , Zhenwei Liang , Xinping Zhang , Ding Weng , Lei Chen , Kui Chen , Xin Han , Jiadao Wang

Journal: ACS Nano

PubMed ID: 36479877

Doi: 10.1021/acsnano.2c07852

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Mir204 and Mir211 suppress synovial inflammation and proliferation in rheumatoid arthritis by targeting Ssrp1

Authors: Qi-Shan Wang , Kai-Jian Fan, Hui Teng , Sijia Chen , Bing-Xin Xu, Di Chen, Ting-Yu Wang

Journal: Elife

Doi: doi.org/10.7554/eLife.78085

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Intranasal bovine β-defensin-5 enhances antituberculosis immunity in a mouse model by a novel protein-based respiratory mucosal vaccine

Authors: Zhengmin Liang, Hao Li, Mengjin Qu, Yiduo Liu, Yuanzhi Wang, Haoran Wang, Yuhui Dong, Yulan Chen, Xin Ge, Xiangmei Zhou

Journal: Virulence

PubMed ID: 35603910

Doi: 10.1080/21505594.2022.2080342

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Molybdopterin biosynthesis pathway contributes to the regulation of SaeRS two-component system by ClpP in

Authors: Na Zhao, Yanan Wang, Junlan Liu, Ziyu Yang, Ying Jian, Hua Wang, Mahmoud Ahmed, Min Li, Taeok Bae, Qian Liu

Journal: Virulence

PubMed ID: 35481455

Doi: 10.1080/21505594.2022.2065961

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Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes

Authors: Jakub Benýšek, Michal Buša, Petra Rubešová, Jindřich Fanfrlík, Martin Lepšík, Jiří Brynda, Zuzana Matoušková, Ulrike Bartz, Martin Horn, Michael Gütschow, Michael Mareš

Journal: J Enzyme Inhib Med Chem

PubMed ID: 35144520

Doi: 10.1080/14756366.2021.2024527

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A De Novo Missense Variant in TUBG2 in a Child with Global Developmental Delay, Microcephaly, Refractory Epilepsy and Perisylvian Polymicrogyria

Authors: Salini Thulasirajah, Xueqi Wang, Erick Sell, Jorge Dávila, David A Dyment, Kristin D Kernohan

Journal: Genes

PubMed ID: 36672848

Doi: 10.3390/genes14010108

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Inhibition of autophagy reduces the rate of fluoride-induced LS8 apoptosis via regulating ATG5 and ATG7

Authors: Lin Zhao, Han Wang, Sijia Liu, Tao Xi, Liyuan Wang, Yang Li, Lu Chen, Ruan Jianping, Kristina Xiao Liang

Journal: J Biochem Mol Toxicol

PubMed ID: 36536498

Doi: 10.1002/jbt.23280

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Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli

Authors: Ashok R Nayak , Pradip K Singh , Jinlei Zhao , Montserrat Samsó , Michael S Donnenberg

Journal: mBio

PubMed ID: 36326250

Doi: 10.1128/mbio.02270-22

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Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis

Authors: Li Ma, Junfeng Wei, Yanli Zeng, Junping Liu, Erhui Xiao, Yuehua Kang, Yi Kang

Journal: Drug Deliv

PubMed ID: 35099348

Doi: 10.1080/10717544.2022.2030428

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Suchilactone inhibits the growth of acute myeloid leukaemia by inactivating SHP2

Authors: Jingjing Wu, Yuan Deng, Xin Zhang, Jingjing Ma, Xinqi Zheng, Yue Chen

Journal: Pharm Biol

PubMed ID: 34962431

Doi: 10.1080/13880209.2021.2017467

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ADAR1 improved Treg cell function through the miR-21b/Foxp3 axis and inhibits the progression of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

Authors: Yanru Zhao, Xiaoyan Zheng, Miaojing Li, Jing Zhao, Xiaoning Wang, Huachao Zhu

Journal: Int Immunopharmacol

PubMed ID: 36577155

Doi: 10.1016/j.intimp.2022.109620

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GmYSL7 controls iron uptake, allocation, and cellular response of nodules in soybean

Authors: Xinying Wu, Yongliang Wang, Qiaohan Ni, Haizhen Li, Xuesong Wu, Zhanxin Yuan, Renhao Xiao, Ziyin Ren, Jingjing Lu, Jinxia Yun, Zhijuan Wang, Xia Li

Journal: J Integr Plant Biol

PubMed ID: 36107150

Doi: 10.1111/jipb.13364

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DeGlyPHER: Highly sensitive site-specific analysis of N-linked glycans on proteins

Authors: Sabyasachi Baboo, Jolene K Diedrich, Salvador Martínez-Bartolomé, Xiaoning Wang, Torben Schiffner, Bettina Groschel, William R Schief, James C Paulson, John R Yates

Journal: Methods Enzymol

PubMed ID: 36948700

Doi: 10.1016/bs.mie.2022.09.004

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Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

Authors: Yunlong Cao, Fanchong Jian, Jing Wang, Yuanling Yu, Weiliang Song, Ayijiang Yisimayi, Jing Wang, Ran An, Xiaosu Chen, Na Zhang, Yao Wang, Peng Wang, Lijuan Zhao, Haiyan Sun, Lingling Yu, Sijie Yang, Xiao Niu, Tianhe Xiao, Qingqing Gu, Fei Shao, Xiaohua Hao, Yanli Xu, Ronghua Jin, Zhongyang Shen, Youchun Wang, Xiaoliang Sunney Xie

Journal: Nature

PubMed ID: 36535326

Doi: 10.1038/s41586-022-05644-7

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Efficient Production of Epoxy-Norbornane from Norbornene by an Engineered P450 Peroxygenase

Authors: Yu Yan, Chenni Zheng, Wei Song, Jing Wu, Liang Guo, Cong Gao, Jia Liu, Xiulai Chen, Meng Zhu, Liming Liu

Journal: Chembiochem

PubMed ID: 36354378

Doi: 10.1002/cbic.202200529

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Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants

Authors: Qihong Yan, Ruitian Hou, Xiaohan Huang, Yanjun Zhang, Ping He, Yudi Zhang, Banghui Liu, Qian Wang, Haiyue Rao, Xianying Chen, Xinwei Zhao, Xuefeng Niu, Jincun Zhao, Xiaoli Xiong, Ling Chen

Journal: Emerg Microbes Infect

PubMed ID: 36288106

Doi: 10.1080/22221751.2022.2140611

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Unamplified and Real-Time Label-Free miRNA-21 Detection Using Solution-Gated Graphene Transistors in Prostate Cancer Diagnosis

Authors: Minghua Deng, Zhanpeng Ren, Huibin Zhang, Ziqin Li, Chenglong Xue, Jianying Wang, Dan Zhang, Huan Yang, Xianbao Wang, Jinhua Li

Journal: Adv Sci (Weinh)

PubMed ID: 36480308

Doi: 10.1002/advs.202205886

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Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA1 and BA2

Authors: Bingjie Hu, Jasper Fuk-Woo Chan, Huan Liu, Yuanchen Liu, Yue Chai, Jialu Shi, Huiping Shuai, Yuxin Hou, Xiner Huang, Terrence Tsz-Tai Yuen, Chaemin Yoon, Tianrenzheng Zhu, Jinjin Zhang, Wenjun Li, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Bao-Zhong Zhang, Kwok-Yung Yuen, Hin Chu

Journal: Emerg Microbes Infect

PubMed ID: 36039901

Doi: 10.1080/22221751.2022.2117098

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SESAME-catalyzed H3T11 phosphorylation inhibits Dot1-catalyzed H3K79me3 to regulate autophagy and telomere silencing

Authors: Fei He , Qi Yu , Min Wang , Rongsha Wang , Xuanyunjing Gong , Feng Ge , Xilan Yu , Shanshan Li

Journal: Nat Commun

PubMed ID: 36473858

Doi: 10.1038/s41467-022-35182-9

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Reduced sensitivity of the SARS-CoV-2 Lambda variant to monoclonal antibodies and neutralizing antibodies induced by infection and vaccination

Authors: Meiyu Wang, Li Zhang, Qianqian Li, Bo Wang, Ziteng Liang, Yeqing Sun, Jianhui Nie, Jiajing Wu, Xiaodong Su, Xiaowang Qu, Yuhua Li, Youchun Wang, Weijin Huang

Journal: Emerg Microbes Infect

PubMed ID: 34818119

Doi: 10.1080/22221751.2021.2008775

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Structure-function analysis of Cdc25 degradation at the maternal-to-zygotic transition

Authors: Patrick L Ferree, Maggie Xing, Jenny Q Zhang, Stefano Di Talia

Journal: Fly (Austin)

PubMed ID: 35227166

Doi: 10.1080/19336934.2022.2043095

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Immune suppression of vaccine-induced CD8 T-cell responses by gamma retrovirus envelope is mediated by interleukin-10-producing CD4 T cells

Authors: Philip Podschwadt, Anna Malyshkina, Sonja Windmann, Athanasios Papadamakis, Leonie Kerkmann, Dennis Lapuente, Matthias Tenbusch, Mengji Lu, Michael Schindler, Karl Sebastian Lang, Wiebke Hansen, Wibke Bayer

Journal: Front Immunol

PubMed ID: 36605206

Doi: 10.3389/fimmu.2022.934399

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The direct binding of AMA1 to erythrocytes defines a RON2-independent invasion pathway

Authors: Seong-Kyun Lee, Leanne M Low, John F Andersen, Lee M Yeoh, Paola Carolina Valenzuela Leon, Damien R Drew, Johannes S P Doehl, Eric Calvo, Louis H Miller, James G Beeson, Karthigayan Gunalan

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36577076

Doi: 10.1073/pnas.2215003120

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Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions

Authors: Da Zou, Zeming Wu, Xin Yi, Yue Hui, Guangze Yang, Yun Liu, Haofei Wang, Anastasia Brooks, Haolu Wang, Xin Liu, Zhi Ping Xu, Michael S Roberts, Huajian Gao, Chun-Xia Zhao

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36574680

Doi: 10.1073/pnas.2214757120

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A novel method for silkworm cocoons self-degumming and its effect on silk fibers

Authors: Riyuan Wang, Yuancheng Wang, Jianxin Song, Chi Tian, Xinyuan Jing, Ping Zhao, Qingyou Xia

Journal: J Adv Res

PubMed ID: 36572337

Doi: 10.1016/j.jare.2022.12.005

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Evaluation of immunological responses to third COVID-19 vaccine among people treated with sphingosine receptor-1 modulators and anti-CD20 therapy

Authors: Ilana Katz Sand, Sacha Gnjatic, Florian Krammer, Kevin Tuballes, Juan Manuel Carreño, Sammita Satyanarayan, Susan Filomena, Erin Staker, Johnstone Tcheou, Aaron Miller, Michelle Fabian, Neha Safi, Jamie Nichols, Jasmin Patel, Stephen Krieger, Stephanie Tankou, Sam Horng, Sylvia Klineova, Erin Beck, Miriam Merad, Fred Lublin

Journal: Mult Scler Relat Disord

PubMed ID: 36628884

Doi: 10.1016/j.msard.2022.104486

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Upconversion nanoparticle-based optogenetic nanosystem for photodynamic therapy and cascade gene therapy

Authors: Xinyue Song, Fengyan Li, Feng Tian, Linlin Ren, Qi Wang, Chengfang Jiang, Tao Yan, Shusheng Zhang

Journal: Acta Biomater

PubMed ID: 36494007

Doi: 10.1016/j.actbio.2022.12.002

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Potential of a novel flagellin epitope as a broad-spectrum vaccine candidate against enteric fever

Authors: Shania Vij, Reena Thakur, Laxmi Kumari, Chander Raman Suri, Praveen Rishi

Journal: Microb Pathog

PubMed ID: 36494021

Doi: 10.1016/j.micpath.2022.105936

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Proteolytic activation of human-specific Olduvai domains by the furin protease

Authors: Ashley Pacheco, Aaron Issaian, Jonathan Davis, Nathan Anderson, Travis Nemkov, Natasia Paukovich, Morkos A Henen, Beat Vögeli, James M Sikela, Kirk Hansen

Journal: Int J Biol Macromol

PubMed ID: 36581038

Doi: 10.1016/j.ijbiomac.2022.12.260

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