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On the origin of appetite: GLWamide in jellyfish represents an ancestral satiety neuropeptide

Authors: Vladimiros Thoma, Shuhei Sakai, Koki Nagata, Yuu Ishii, Shinichiro Maruyama, Ayako Abe, Shu Kondo, Masakado Kawata, Shun Hamada, Ryusaku Deguchi, Hiromu Tanimoto

Journal: Proc Natl Acad Sci U S A

PubMed ID: 37011192

Doi: 10.1073/pnas.2221493120

Products & Services: Molecular Biology Reagents

Allosteric role of the citrate synthase homology domain of ATP citrate lyase

Authors: Xuepeng Wei, Kollin Schultz, Hannah L Pepper, Emily Megill, Austin Vogt, Nathaniel W Snyder, Ronen Marmorstein

Journal: Nat Commun

PubMed ID: 37076498

Doi: 10.1038/s41467-023-37986-9

Products & Services: Codon Optimization

Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence

Authors: Kathryn M Hastie, Xiaoying Yu, Fernanda Ana-Sosa-Batiz, Dawid S Zyla, Stephanie S Harkins, Chitra Hariharan, Hal Wasserman, Michelle A Zandonatti, Robyn Miller, Erin Maule, Kenneth Kim, Kristen M Valentine, Sujan Shresta, Erica Ollmann Saphire

Journal: Cell Rep

PubMed ID: 37083327

Doi: 10.1016/j.celrep.2023.112421

Products & Services: Recombinant Proteins

Biochemical characterization of RNase R 2'-O-methylation sensitivity

Authors: Xiaolan Lu, Xiangwen Gu, Yong Li, Yifan Wu, Qiang Wang, Wenkui Yu, Qihan Chen

Journal: Biochimie

PubMed ID: 37105299

Doi: 10.1016/j.biochi.2023.04.016

Products & Services: Proteins, Expression, Isolation and Analysis

A small epitope shared by p53 and an unrelated protein upregulated after adenovirus infection

Authors: Jessica J Miciak, Fred Bunz

Journal: biorxiv

PubMed ID: 37162859

Doi: 10.1101/2023.04.28.538733

Screening antivirals with a mCherry-expressing recombinant bovine respiratory syncytial virus: a proof of concept using cyclopamine

Authors: Jenna Fix, Delphyne Descamps, Marie Galloux, Cécile Ferret, Edwige Bouguyon, Siamak Zohari, Katarina Näslund, Sara Hägglund, Ralf Altmeyer, Jean-François Valarcher, Sabine Riffault, Jean-François Eléouët

Journal: Vet Res

PubMed ID: 37069656

Doi: 10.1186/s13567-023-01165-x

Products & Services: Molecular Biology Reagents

Functional Characterization of the Putative POT from

Authors: Hani Gharabli, Maria Rafiq, Anna Iqbal, Ruyu Yan, Nanda G Aduri, Neha Sharma, Bala K Prabhala, Osman Mirza

Journal: Biology (Basel)

PubMed ID: 37237465

Doi: 10.3390/biology12050651

Products & Services: Combinatorial DNA Libraries

NMDARs control object recognition memory destabilization and reconsolidation

Authors: Janine I Rossato, Andressa Radiske, Maria Carolina Gonzalez, Gênedy Apolinário, Raquel L S de Araújo, Lia R M Bevilaqua, Martín Cammarota

Journal: Brain Res Bull

PubMed ID: 37011815

Doi: 10.1016/j.brainresbull.2023.03.013

Products & Services: Custom DNA/RNA Oligos

Chemiluminescence Biosensor for the Determination of Cardiac Troponin I (cTnI)

Authors: Robert Tannenberg, Martin Paul, Bettina Röder, Santosh L Gande, Sridhar Sreeramulu, Krishna Saxena, Christian Richter, Harald Schwalbe, Claudia Swart, Michael G Weller

Journal: Biosensors (Basel)

PubMed ID: 37185530

Doi: 10.3390/bios13040455

Products & Services: DNA Sequencing

Ebselen restores peri-implantitis-induced osteogenic inhibition via suppressing BMSCs ferroptosis

Authors: Ziqing Huang, Guanhui Chen, Hiokuan Wu, Xiaoqiong Huang, Ruogu Xu, Feilong Deng, Yiming Li

Journal: Exp Cell Res

PubMed ID: 37116735

Doi: 10.1016/j.yexcr.2023.113612

Products & Services: Proteins, Expression, Isolation and Analysis

Rational development of multicomponent mRNA vaccine candidates against mpox

Authors: Rong-Rong Zhang, Zheng-Jian Wang, Yi-Long Zhu, Wei Tang, Chao Zhou, Suo-Qun Zhao, Mei Wu, Tao Ming, Yong-Qiang Deng, Qi Chen, Ning-Yi Jin, Qing Ye, Xiao Li, Cheng-Feng Qin

Journal: Emerging microbes & infections

PubMed ID: 36947428

Doi: 10.1080/22221751.2023.2192815

Products & Services: Peptide Synthesis

The TORC1 activates Rpd3L complex to deacetylate Ino80 and H2A.Z and repress autophagy

Authors: Xin Li, Qianyun Mei, Qi Yu, Min Wang, Fei He, Duncheng Xiao, Huan Liu, Feng Ge, Xilan Yu, Shanshan Li

Journal: Science Advances

PubMed ID: 36888706

Doi: 10.1126/sciadv.ade8312

Products & Services: DNA Sequencing

Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2

Authors: Hyung J Kwon, Jun Zhang, Matina Kosikova, Weichun Tang, Uriel Ortega-Rodriguez, Hanqin Peng, Clement A Meseda, Cyntia L Pedro, Falko Schmeisser, Jianming Lu, Insung Kang, Bin Zhou, Charles T Davis, David E Wentworth, Wilbur H Chen, Mallory C Shriver, Robin S Barnes, Marcela F Pasetti, Jerry P Weir, Bing Chen, Hang Xie

Journal: J Med Virol

PubMed ID: 36916782

Doi: 10.1002/jmv.28673

Products & Services: Proteins, Expression, Isolation and Analysis

The Zinc-BED Transcription Factor Bedwarfed Promotes Proportional Dendritic Growth and Branching through Transcriptional and Translational Regulation in

Authors: Shatabdi Bhattacharjee, Eswar Prasad R Iyer, Srividya Chandramouli Iyer, Sumit Nanda, Myurajan Rubaharan, Giorgio A Ascoli, Daniel N Cox

Journal: Int J Mol Sci

PubMed ID: 37047316

Doi: 10.3390/ijms24076344

Products & Services: Molecular Biology Reagents

Comparison of Immunogenicity and Reactogenicity of Five Primary Series of COVID-19 Vaccine Regimens against Circulating SARS-CoV-2 Variants of Concern among Healthy Thai Populations

Authors: Tavitiya Sudjaritruk, Oramai Mueangmo, Jutamad Saheng, Poramed Winichakoon, Parichat Salee, Worawan Wongjak, Tanachot Chaito, Jutarat Praparattanapan, Khanuengnit Nuket, Nuttarika Solai, Jiraprapa Wipasa, Kriangkrai Chawansuntati, Romanee Chaiwarith

Journal: Vaccines (Basel)

PubMed ID: 36992147

Doi: 10.3390/vaccines11030564

Products & Services: Proteins, Expression, Isolation and Analysis

DNA accelerates the protease inhibition of a bacterial serpin chloropin

Authors: Jiawei Xu, Wei Ye, Ting Ting Yang, Teng Yan, Haiyan Cai, Aiwu Zhou, Yufeng Yang

Journal: Front Mol Biosci

PubMed ID: 37065444

Doi: 10.3389/fmolb.2023.1157186

Products & Services: Proteins, Expression, Isolation and Analysis

SWIP mediates retromer-independent membrane recruitment of the WASH complex

Authors: Vojtěch Dostál, Tereza Humhalová, Pavla Beránková, Ondřej Pácalt, Lenka Libusová

Journal: Traffic

PubMed ID: 36995008

Doi: 10.1111/tra.12884

Products & Services: Stable Cell Lines

Re-engineering a lost trait: , a master regulator of arbuscular mycorrhizal symbiosis, affects genes for immunity and metabolism of non-host Arabidopsis when restored long after its evolutionary loss

Authors: Eli D Hornstein, Melodi Charles, Megan Franklin, Brianne Edwards, Simina Vintila, Manuel Kleiner, Heike Sederoff

Journal: biorxiv

PubMed ID: 36945518

Doi: 10.1101/2023.03.06.531368

Products & Services: Proteins, Expression, Isolation and Analysis

The NAC transcription factor ONAC083 negatively regulates rice immunity against Magnaporthe oryzae by directly activating transcription of the RING‐H2 gene OsRFPH2‐6

Authors: Yan Bi , Hui Wang , Xi Yuan , Yuqing Yan , Dayong Li , Fengming Song

Journal: J Integr Plant Biol

PubMed ID: 36308720

Doi: 10.1111/jipb.13399

Products & Services: Proteins, Expression, Isolation and Analysis

Interactions of Nanoscale Self-Assembled Peptide-Based Assemblies with Glioblastoma Cell Models and Spheroids

Authors: Charlotta G Lebedenko, Molly E Murray, Beatriz G Goncalves, Diego S Perez， Dominic J Lambo, Ipsita A Banerjee

Journal: ACS Omega

PubMed ID: 37033803

Doi: 10.1021/acsomega.2c08049

Products & Services: Peptides and Peptide Library

Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein

Authors: Patrick O Byrne, Brian E Fisher, David R Ambrozak, Elizabeth G Blade, Yaroslav Tsybovsky, Barney S Graham, Jason S McLellan, Rebecca J Loomis

Journal: Nat Commun

PubMed ID: 36932063

Doi: 10.1038/s41467-023-36995-y

Products & Services: Proteins, Expression, Isolation and Analysis

DIA-based technology explores hub pathways and biomarkers of neurological recovery in ischemic stroke after rehabilitation

Authors: Wei Hu, Ping Li, Nianju Zeng, Sheng Tan

Journal: Front Neurol

PubMed ID: 36959823

Doi: 10.3389/fneur.2023.1079977

Products & Services: Proteins, Expression, Isolation and Analysis

Heterologous production of polycyclopropanated fatty acids and their methyl esters in Streptomyces

Authors: Kevin Yin, Pablo Cruz-Morales, Christopher M Whitford, Jay D Keasling

Journal: STAR Protoc

PubMed ID: 36952335

Doi: 10.1016/j.xpro.2023.102190

Products & Services: Proteins, Expression, Isolation and Analysis

Combining elicitor treatment of chitosan, methyl jasmonate, and cyclodextrin to induce the generation of immune response bioactive peptides in peanut hairy root culture

Authors: Chanyanut Pankaew, Kanitha Supdensong, Chonnikan Tothong, Sittiruk Roytrakul, Narumon Phaonakrop, Anupan Kongbangkerd, Apinun Limmongkon

Journal: Plant Sci

PubMed ID: 36914116

Doi: 10.1016/j.plantsci.2023.111670

Products & Services: Proteins, Expression, Isolation and Analysis

Molluscum Contagiosum Virus Protein MC008 Targets NF-κB Activation by Inhibiting Ubiquitination of NEMO

Authors: Thomas Phelan, Clara Lawler, Andreas Pichlmair, Mark A Little, Andrew G Bowie, Gareth Brady

Journal: J Virol

PubMed ID: 36916940

Doi: 10.1128/jvi.00108-23

Products & Services: Proteins, Expression, Isolation and Analysis

Functional SARS-CoV-2-specific T cells of donor origin in allogeneic stem cell transplant recipients of a T-cell-replete infusion: A prospective observational study

Authors: Corinna La Rosa, Flavia Chiuppesi, Yoonsuh Park, Qiao Zhou, Dongyun Yang, Ketevan Gendzekhadze, Minh Ly, Jing Li, Teodora Kaltcheva, Sandra Ortega Francisco, Miguel-Angel Gutierrez, Haris Ali, Salman Otoukesh, Idoroenyi Amanam, Amandeep Salhotra, Vinod A Pullarkat, Ibrahim Aldoss, Michael Rosenzweig, Ahmed M Aribi, Anthony S Stein, Guido Marcucci, Sanjeet Singh Dadwal, Ryotaro Nakamura, Stephen J Forman, Monzr M Al Malki, Don J Diamond

Journal: Front Immunol

PubMed ID: 36936918

Doi: 10.3389/fimmu.2023.1114131

Products & Services: Molecular Biology Reagents

Process development for an effective COVID-19 vaccine candidate harboring recombinant SARS-CoV-2 delta plus receptor binding domain produced by Pichia pastoris

Authors: Sibel Kalyoncu, Semiramis Yilmaz, Ayca Zeybek Kuyucu, Dogu Sayili, Olcay Mert, Hakan Soyturk, Seyda Gullu, Huseyin Akinturk, Erhan Citak, Merve Arslan, Melda Guray Taskinarda, Ibrahim Oguzhan Tarman, Gizem Yilmazer Altun, Ceren Ozer, Ridvan Orkut, Aysegul Demirtas, Idil Tilmensagir, Umur Keles, Ceren Ulker, Gizem Aralan, Yavuz Mercan, Muge Ozkan, Hasan Onur Caglar, Gizem Arik, Mehmet Can Ucar, Muzaffer Yildirim, Tugce Canavar Yildirim, Dilara Karadag, Erhan Bal, Aybike Erdogan, Serif Senturk, Serdar Uzar, Hakan Enul, Cumhur Adiay, Fahriye Sarac, Arzu Tas Ekiz, Irem Abaci, Ozge Aksoy, Hivda Ulbegi Polat, Saban Tekin, Stefan Dimitrov, Aykut Ozkul, Gerhard Wingender, Ihsan Gursel, Mehmet Ozturk, Mehmet Inan

Journal: Sci Rep

PubMed ID: 36997624

Doi: 10.1038/s41598-023-32021-9

Products & Services: Molecular Biology Reagents

Exogenous aralar/slc25a12 can replace citrin/slc25a13 as malate aspartate shuttle component in liver

Authors: Luis González-Moreno, Andrea Santamaría-Cano, Alberto Paradela, María Luz Martínez-Chantar, Miguel Á Martín, Mercedes Pérez-Carreras, Alberto García-Picazo, Jesús Vázquez, Enrique Calvo, Gloria González-Aseguinolaza, Takeyori Saheki, Araceli Del Arco, Jorgina Satrústegui, Laura Contreras

Journal: Mol Genet Metab Rep

PubMed ID: 36967723

Doi: 10.1016/j.ymgmr.2023.100967

Products & Services: Proteins, Expression, Isolation and Analysis

Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers

Authors: Pete Schmidt, Kristin Narayan, Yong Li, Chengzi I Kaku, Michael E Brown, Elizabeth Champney, James C Geoghegan, Maximiliano Vásquez, Eric M Krauland, Thomas Yockachonis, Shuangyi Bai, Bronwyn M Gunn, Anthony Cammarata, Christopher M Rubino, Paul Ambrose, Laura M Walker

Journal: Sci Transl Med

PubMed ID: 36947596

Doi: 10.1126/scitranslmed.adg2783

Products & Services: Proteins, Expression, Isolation and Analysis

Sortase A transpeptidation produces seamless, unbranched biotinylated nanobodies for multivalent and multifunctional applications

Authors: Eugene M Obeng, David L Steer, Alex J Fulcher, Kylie M Wagstaff

Journal: Nanoscale Adv

PubMed ID: 37056610

Doi: 10.1039/d3na00014a

Products & Services: Gene Synthesis

Recombinant Modified Vaccinia Virus Ankara Expressing a Glycosylation Mutant of Dengue Virus NS1 Induces Specific Antibody and T-Cell Responses in Mice

Authors: Lucas Wilken, Sonja Stelz, Ayse Agac, Gerd Sutter, Chittappen Kandiyil Prajeeth, Guus F Rimmelzwaan

Journal: Vaccines (Basel)

PubMed ID: 37112626

Doi: 10.3390/vaccines11040714

Products & Services: Recombinant Proteins

Deoxyshikonin inhibited rotavirus replication by regulating autophagy and oxidative stress through SIRT1/FoxO1/Rab7 axis

Authors: Haohai Huang, Dan Liao, Bin He, Rong Pu, Yejia Cui, Guanghui Zhou

Journal: Microb Pathog

PubMed ID: 36907361

Doi: 10.1016/j.micpath.2023.106065

Products & Services: Proteins, Expression, Isolation and Analysis

Establishment and Application of Indirect ELISAs for Detecting Antibodies against Goose Astrovirus Genotype 1 and 2

Authors: Mengran Zhang, Xinyu Wei, Jing Qian, Zhengyu Yu, Xin Liu, Yan Luo, Haitao Zhang, Youfang Gu, Yin Li

Journal: Vaccines (Basel)

PubMed ID: 36992248

Doi: 10.3390/vaccines11030664

Products & Services: Proteins, Expression, Isolation and Analysis

Regulated control of virus replication by 4-hydroxytamoxifen-induced splicing

Authors: Zhenghao Zhao, Busen Wang, Shipo Wu, Zhe Zhang, Yi Chen, Jinlong Zhang, Yudong Wang, Danni Zhu, Yao Li, Jinghan Xu, Lihua Hou, Wei Chen

Journal: Front Microbiol

PubMed ID: 36992923

Doi: 10.3389/fmicb.2023.1112580

Products & Services: Recombinant Antibody Expression

DAB2IP-knocking down resulted in radio-resistance of breast cancer cells is associated with increased hypoxia and vasculogenic mimicry formation

Authors: Xiangyan Zhang, Quanxin Wang, Ruiqi Zhang, Zhaolu Kong

Journal: Int J Radiat Biol

PubMed ID: 36947637

Doi: 10.1080/09553002.2023.2194390

Products & Services: Proteins, Expression, Isolation and Analysis

Increasing lysergic acid levels for ergot alkaloid biosynthesis: Directing catalysis the F-G loop of Clavine oxidases

Authors: Li Rong Lim, Garrett Wong, Maybelle K Go, Wen Shan Yew

Journal: Front Microbiol

PubMed ID: 37007471

Doi: 10.3389/fmicb.2023.1150937

Products & Services: Proteins, Expression, Isolation and Analysis

DNA sensing via the cGAS/STING pathway activates the immunoproteasome and adaptive T-cell immunity

Authors: Xinyuan Wang, Huabin Zhang, Yuqin Wang, Laylan Bramasole, Kai Guo, Fatima Mourtada, Thomas Meul, Qianjiang Hu, Valeria Viteri, Ilona Kammerl, Melanie Konigshoff, Mareike Lehmann, Thomas Magg, Fabian Hauck, Isis E Fernandez, Silke Meiners

Journal: EMBO J

PubMed ID: 36912165

Doi: 10.15252/embj.2022110597

Products & Services: Peptide Synthesis

Ex Vivo Immune Responsiveness to SARS-CoV-2 Omicron BA51 Following Vaccination with Unmodified mRNA-Vaccine

Authors: Anna Sabrina Kuechler, Eva Heger, Maike Wirtz, Sandra Weinhold, Markus Uhrberg, Fritz Boege, Karin Schulze-Bosse

Journal: Vaccines (Basel)

PubMed ID: 36992182

Doi: 10.3390/vaccines11030598

Products & Services: Molecular Biology Reagents

Integrating biopolymer design with physical unclonable functions for anticounterfeiting and product traceability in agriculture

Authors: Hui Sun, Saurav Maji, Anantha P Chandrakasan, Benedetto Marelli

Journal: Sci Adv

PubMed ID: 36947609

Doi: 10.1126/sciadv.adf1978

Products & Services: Peptide Synthesis

Evaluation and deployment of isotype-specific salivary antibody assays for detecting previous SARS-CoV-2 infection in children and adults

Authors: Amy C Thomas, Elizabeth Oliver, Holly E Baum, Kapil Gupta, Kathryn L Shelley, Anna E Long, Hayley E Jones, Joyce Smith, Benjamin Hitchings, Natalie di Bartolo, Kate Vasileiou, Fruzsina Rabi, Hanin Alamir, Malak Eghleilib, Ore Francis, Jennifer Oliver, Begonia Morales-Aza, Ulrike Obst, Debbie Shattock, Rachael Barr, Lucy Collingwood, Kaltun Duale, Niall Grace, Guillaume Gonnage Livera, Lindsay Bishop, Harriet Downing, Fernanda Rodrigues, Nicholas Timpson, Caroline L Relton, Ashley Toye, Derek N Woolfson, Imre Berger, Anu Goenka, Andrew D Davidson, Kathleen M Gillespie, Alistair J K Williams, Mick Bailey, Ellen Brooks-Pollock, Adam Finn, Alice Halliday

Journal: Commun Med (Lond)

PubMed ID: 36922542

Doi: 10.1038/s43856-023-00264-2

Products & Services: Proteins, Expression, Isolation and Analysis

Sniper2L is a high-fidelity Cas9 variant with high activity

Authors: Young-Hoon Kim, Nahye Kim, Ikenna Okafor, Sungchul Choi, Seonwoo Min, Joonsun Lee, Seung-Min Bae, Keunwoo Choi, Janice Choi, Vinayak Harihar, Youngho Kim, Jin-Soo Kim, Benjamin P Kleinstiver, Jungjoon K Lee, Taekjip Ha, Hyongbum Henry Kim

Journal: Nat Chem Biol

PubMed ID: 36894722

Doi: 10.1038/s41589-023-01279-5

Products & Services: Proteins, Expression, Isolation and Analysis

In vivo imaging of calcium dynamics in zebrafish hepatocytes

Authors: Macarena Pozo-Morales, Inés Garteizgogeascoa, Camille Perazzolo, Juhoon So, Donghun Shin, Sumeet Pal Singh

Journal: Hepatology

PubMed ID: 35829917

Doi: 10.1002/hep.32663

Products & Services: Gene Synthesis

Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train

Authors: Yuanyuan Ma, Jun He, Shaobai Li, Deqiang Yao, Chenhui Huang, Jian Wu, Ming Lei

Journal: Nat Commun

PubMed ID: 36932088

Doi: 10.1038/s41467-023-37208-2

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization and utility of two monoclonal antibodies to cholera toxin B subunit

Authors: Noel Verjan Garcia, Ian Carlosalberto Santisteban Celis, Matthew Dent, Nobuyuki Matoba

Journal: Sci Rep

PubMed ID: 36922604

Doi: 10.1038/s41598-023-30834-2

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis of Janus kinase trans-activation

Authors: Nathanael A Caveney, Robert A Saxton, Deepa Waghray, Caleb R Glassman, Naotaka Tsutsumi, Stevan R Hubbard, K Christopher Garcia

Journal: Cell Rep

PubMed ID: 36867534

Doi: 10.1016/j.celrep.2023.112201

Products & Services: Proteins, Expression, Isolation and Analysis

Improving adenine and dual base editors through introduction of TadA-8e and Rad51DBD

Authors: Niannian Xue, Xu Liu, Dan Zhang, Youming Wu, Yi Zhong, Jinxin Wang, Wenjing Fan, Haixia Jiang, Biyun Zhu, Xiyu Ge, Rachel V L Gonzalez, Liang Chen, Shun Zhang, Peilu She, Zhilin Zhong, Jianjian Sun, Xi Chen, Liren Wang, Zhimin Gu, Ping Zhu, Mingyao Liu, Dali Li, Tao P Zhong, Xiaohui Zhang

Journal: Nat Commun

PubMed ID: 36869044

Doi: 10.1038/s41467-023-36887-1

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis for enzymatic terminal C-H bond functionalization of alkanes

Authors: Jin Chai, Gongrui Guo, Sean M McSweeney, John Shanklin, Qun Liu

Journal: Nat Struct Mol Biol

PubMed ID: 36997762

Doi: 10.1038/s41594-023-00958-0

Products & Services: Proteins, Expression, Isolation and Analysis

Epigenetic immune monitoring for COVID-19 disease course prognosis

Authors: Björn Samans, Marta Rosselló Chornet, Araceli Rosselló Chornet, Janine Jung, Konstantin Schildknecht, Laura Lozza, Lourdes Alos Zaragoza, Javier Hernández Laforet, Nina Babel, Sven Olek

Journal: Front Immunol

PubMed ID: 36999021

Doi: 10.3389/fimmu.2023.1107900

Products & Services: Molecular Biology Reagents

Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates

Authors: Yvonne J Rosenberg, Tracy Ordonez, Urjeet S Khanwalkar, Philip Barnette, Shilpi Pandey, Iara M Backes, Claire E Otero, Benjamin S Goldberg, Andrew R Crowley, David A Leib, Mariya B Shapiro, Xiaoming Jiang, Lori A Urban, Jonathan Lees, Ann J Hessell, Sallie Permar, Nancy L Haigwood, Margaret E Ackerman

Journal: MBio

PubMed ID: 36946726

Doi: 10.1128/mbio.00341-23

Products & Services: Recombinant Proteins

Bispecific antibodies combine breadth, potency, and avidity of parental antibodies to neutralize sarbecoviruses

Authors: Laura Radić, Kwinten Sliepen, Victor Yin, Mitch Brinkkemper, Joan Capella-Pujol, Angela I Schriek, Jonathan L Torres, Sandhya Bangaru, Judith A Burger, Meliawati Poniman, Ilja Bontjer, Joey H Bouhuijs, David Gideonse, Dirk Eggink, Andrew B Ward, Albert J R Heck, Marit J Van Gils, Rogier W Sanders, Janke Schinkel

Journal: iScience

PubMed ID: 37063468

Doi: 10.1016/j.isci.2023.106540

Products & Services: Recombinant Proteins

Process development and characterization of recombinant nucleocapsid protein for its application on COVID-19 diagnosis

Authors: Luãnna Elisa Liebscher Vidal, Janaina Figueira-Mansur, Patrícia Barbosa Jurgilas, Ana Paula Correa Argondizzo, Cristiane Pinheiro Pestana, Fernanda Otaviano Martins, Haroldo Cid da Silva Junior, Mariana Miguez, Bernardo Oliveira Loureiro, Christiane de Fátima Silva Marques, Karen Soares Trinta, Leila Botelho Rodrigues da Silva, Marcelle Bral de Mello, Edimilson Domingos da Silva, Renata Chagas Bastos, Gabriela Esteves

Journal: Protein Expr Purif

PubMed ID: 36921810

Doi: 10.1016/j.pep.2023.106263

Products & Services: Molecular Biology Reagents

Heterologous prime-boost immunisation with mRNAand AdC68-based 2019-nCoV variant vaccines induces broad-spectrum immune responses in mice

Authors: Xingxing Li, Jingjing Liu, Wenjuan Li, Qinhua Peng, Miao Li, Zhifang Ying, Zelun Zhang, Xinyu Liu, Xiaohong Wu, Danhua Zhao, Lihong Yang, Shouchun Cao, Yanqiu Huang, Leitai Shi, Hongshan Xu, Yunpeng Wang, Guangzhi Yue, Yue Suo, Jianhui Nie, Weijin Huang, Jia Li, Yuhua Li

Journal: frontiers in immunology

PubMed ID: 37006275

Doi: 10.3389/fimmu.2023.1142394

Products & Services: Peptides and Peptide Library B.1.617.2 刺突蛋白多肽库 B.1.1.529 刺突蛋白多肽库

Effect of preliminary stresses on the induction of viable but non-culturable Escherichia coli O157:H7 NCTC 12900 and Staphylococcus aureus ATCC 6538

Authors: Dong Yang, Liang Zhao, Lei Rao, Xiaojun Liao

Journal: Food Res Int

PubMed ID: 37087272

Doi: 10.1016/j.foodres.2023.112710

Products & Services: Proteins, Expression, Isolation and Analysis

Combination of mathematics and label-free proteomics for discovering keratin-derived specific peptide biomarkers to distinguish animal horn-derived traditional Chinese medicines

Authors: Rui Liu, Jiayao Tang, Wenxing Wu, Jingjing Zhao, Zhaoying Zhu, Hai-Ou Gu, Zhibin Wang, Ming Zhao, Jin-Ao Duan

Journal: J Sep Sci

PubMed ID: 36821105

Doi: 10.1002/jssc.202200949

Products & Services: Proteins, Expression, Isolation and Analysis

Using low-cost disposable immunosensor based on flexible PET screen-printed electrode modified with carbon black and gold nanoparticles for sensitive detection of SARS-CoV-2

Authors: Luís M C Ferreira, Isabela F Reis, Paulo R Martins, Luiz H Marcolino-Junior, Marcio F Bergamini, Jessica R Camargo, Bruno C Janegitz, Fernando C Vicentini

Journal: Talanta Open

PubMed ID: 36959870

Doi: 10.1016/j.talo.2023.100201

Products & Services: Molecular Biology Reagents

CDetectionv2: One-pot assay for the detection of SARS-CoV-2

Authors: Xinge Wang, Yangcan Chen, Xuejia Cheng, Si-Qi Wang, Yanping Hu, Yingmei Feng, Ronghua Jin, Kangping Zhou, Ti Liu, Jianxing Wang, Kai Pan, Bing Liu, Jie Xiang, Yanping Wang, Qi Zhou, Ying Zhang, Weiye Pan, Wei Li

Journal: Front Microbiol

PubMed ID: 37032875

Doi: 10.3389/fmicb.2023.1158163

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Exposure to diverse sarbecoviruses indicates frequent zoonotic spillover in human communities interacting with wildlife

Authors: Tierra Smiley Evans, Chee Wah Tan, Ohnmar Aung, Sabai Phyu, Htin Lin, Lark L Coffey, Aung Than Toe, Pyaephyo Aung, Tin Htun Aung, Nyein Thu Aung, Christopher M Weiss, Kyaw Zin Thant, Zaw Than Htun, Suzan Murray, Linfa Wang, Christine Kreuder Johnson, Hlaing Myat Thu

Journal: Int J Infect Dis

PubMed ID: 36870470

Doi: 10.1016/j.ijid.2023.02.015

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A Putative Receptor for Ferritin in Mollusks: Characterization of the Insulin-like Growth Factor Type 1 Receptor

Authors: Bowen Huang, Qin Liu, Changming Bai, Chen Li, Chongming Wang, Lusheng Xin

Journal: Int J Mol Sci

PubMed ID: 37047145

Doi: 10.3390/ijms24076175

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Preclinical evaluation of immunogenicity, efficacy and safety of a recombinant plant-based SARS-CoV-2 RBD vaccine formulated with 3M-052-Alum adjuvant

Authors: Waranyoo Phoolcharoen, Balamurugan Shanmugaraj, Narach Khorattanakulchai, Piyanate Sunyakumthorn, Sathit Pichyangkul, Pornnarin Taepavarapruk, Wanlapa Praserthsee, Suchinda Malaivijitnond, Suwimon Manopwisedjaroen, Arunee Thitithanyanont, Kanjana Srisutthisamphan, Anan Jongkaewwattana, Mark Tomai, Christopher B Fox, Suthira Taychakhoonavudh

Journal: Vaccine

PubMed ID: 36963999

Doi: 10.1016/j.vaccine.2023.03.027

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Phase I Trial of a Therapeutic DNA Vaccine for Preventing Hepatocellular Carcinoma from Chronic Hepatitis C Virus (HCV) Infection

Authors: Jeffrey M Jacobson, David Zahrieh, Carrie A Strand, Marcia Cruz-Correa, Surakit Pungpapong, Lewis R Roberts, Sumithra J Mandrekar, Luz Maria Rodriguez, Jean Boyer, Idania Marrero, Kimberly A Kraynyak, Matthew P Morrow, Albert J Sylvester, Jan M Pawlicki, Elisabeth Gillespie, Eduardo Barranco, Ellen Richmond, Asad Umar, David B Weiner, Paul J Limburg

Journal: Cancer Prev Res (Phila)

PubMed ID: 36534786

Doi: 10.1158/1940-6207.CAPR-22-0217

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Cloning, characterization, and heterologous expression of a candidate Hirudin gene from the salivary gland transcriptome of Hirudo nipponia

Authors: Ping Shi, Jian Wei, Huajian You, Shijiang Chen, Fayin Tan, Zenghui Lu

Journal: Sci Rep

PubMed ID: 36973525

Doi: 10.1038/s41598-023-32303-2

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Regulation of neurofilament length and transport by a dynamic cycle of phospho-dependent polymer severing and annealing

Authors: Atsuko Uchida, Juan Peng, Anthony Brown

Journal: Mol Biol Cell

PubMed ID: 36989035

Doi: 10.1091/mbc.E23-01-0024

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JNK Activation in Alzheimer's Disease Is Driven by Amyloid β and Is Associated with Tau Pathology

Authors: Maite Solas, Silvia Vela, Cristian Smerdou, Eva Martisova, Iván Martínez-Valbuena, María-Rosario Luquin, María J Ramírez

Journal: ACS Chem Neurosci

PubMed ID: 36976903

Doi: 10.1021/acschemneuro.3c00093

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IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity

Authors: Anastasia Geladaris, Silke Häusser-Kinzel, Roxanne Pretzsch, Nitzan Nissimov, Klaus Lehmann-Horn, Darius Häusler, Martin S Weber

Journal: Acta Neuropathol

PubMed ID: 36854993

Doi: 10.1007/s00401-023-02552-6

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IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway

Authors: Juan Gao, Shiqi Suo, Jingxia Li, Chunxia Wang, Ranran Deng, Yuxia Hu, Chunzheng Zhang

Journal: Exp Ther Med

PubMed ID: 37006880

Doi: 10.3892/etm.2023.11868

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miR-126 mitigates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting the ERK1/2 and Bcl-2 pathways

Authors: Ying Zhang, Yiping Dong, Qiushi Wei, Zhikun Zhuang, Youwen Liu, Qiang Yuan, Wei He, Zhenhao Jing, Jitian Li, Peifeng Li, Leilei Zhang, Zhinan Hong, Ning Zhang, Haibin Wang, Wuyin Li

Journal: Acta Biochim Biophys Sin (Shanghai)

PubMed ID: 36942990

Doi: 10.3724/abbs.2023016

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Immunoglobulin G subclasses confer protection against bloodstream dissemination through distinct mechanisms in mouse models

Authors: Xinhai Chen, Haley Gula, Tonu Pius, Chong Ou, Margaryta Gomozkova, Lai-Xi Wang, Olaf Schneewind, Dominique Missiakas

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36972444

Doi: 10.1073/pnas.2220765120

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Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases

Authors: George D Lampe, Rebeca T King, Tyler S Halpin-Healy, Sanne E Klompe, Marcus I Hogan, Phuc Leo H Vo, Stephen Tang, Alejandro Chavez, Samuel H Sternberg

Journal: biorxiv

PubMed ID: 36993517

Doi: 10.1101/2023.03.17.533036

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KRT5 mutation regulate melanin metabolism through notch signalling pathway between keratinocytes and melanocytes

Authors: Weixue Jia, Yuanyuan Zhang, Xue Wang, Lingling Luo, Heng Sun, Yiqun Jiang, Jianbo Wang, Qiuxia Mao, Youming Guo, Lingzhuo Kong, Ran Mo, Chengrang Li

Journal: Exp Dermatol

PubMed ID: 36809573

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Conservation and divergence of flg22, pep1 and nlp20 in activation of immune response and inhibition of root development

Authors: Yan Huang, Junmei Cui, Meng Li, Rongqian Yang, Yang Hu, Xiaosong Yu, Ying Chen, Qiqi Wu, Huipeng Yao, Guozhi Yu, Jinya Guo, Huaiyu Zhang, Shuang Wu, Yi Cai

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PubMed ID: 36963637

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The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma

Authors: Lucia Morgado-Palacin, Jessie A Brown, Thomas F Martinez, Juana M Garcia-Pedrero, Farhad Forouhar, S Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodriguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F Fernandez, Mario F Fraga, Arianna L Kim, Jorge Santos-Juanes, David M Owens, Juan P Rodrigo, Alan Saghatelian, Adolfo A Ferrando

Journal: Nat Commun

PubMed ID: 36899004

Doi: 10.1038/s41467-023-36713-8

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Colorectal cancer-derived extracellular vesicles containing HSP70 enhance macrophage phagocytosis by up-regulating MARCO expression

Authors: Yu Sun, Wenjun Xiao, Yang Yu, Yuchen Jiang, Zhijie Xiao, Defa Huang, Tianyu Zhong, Jiang Li, Xi Xiang, Yulong He, Zhigang Li

Journal: Exp Cell Res

PubMed ID: 36958650

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Anti-human immunodeficiency virus-1 activity of MoMo30 protein isolated from the traditional African medicinal plant Momordica balsamina

Authors: Mahfuz Khan, Amad Diop, Erick Gbodossou, Peng Xiao, Morgan Coleman, Kenya De Barros, Hao Duong, Vincent C Bond, Virginia Floyd, Kofi Kondwani, Valerie Montgomery Rice, Sandra Harris-Hooker, Francois Villinger, Michael D Powell

Journal: Virol J

PubMed ID: 36949470

Doi: 10.1186/s12985-023-02010-5

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Identification of tagged glycans with a protein nanopore

Authors: Minmin Li, Yuting Xiong, Yuchen Cao, Chen Zhang, Yuting Li, Hanwen Ning, Fan Liu, Han Zhou, Xiaonong Li, Xianlong Ye, Yue Pang, Jiaming Zhang, Xinmiao Liang, Guangyan Qing

Journal: Nat Commun

PubMed ID: 36977665

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Nuclease activity of Plasmodium falciparum Alba family protein PfAlba3

Authors: Chinmoy Banerjee, Shiladitya Nag, Manish Goyal, Debanjan Saha, Asim Azhar Siddiqui, Somnath Mazumder, Subhashis Debsharma, Saikat Pramanik, Uday Bandyopadhyay

Journal: Cell Rep

PubMed ID: 36947546

Doi: 10.1016/j.celrep.2023.112292

Arc ubiquitination regulates endoplasmic reticulum-mediated Ca release and CaMKII signaling

Authors: Mohammad A Ghane, Wei Wei, Dina W Yakout, Zachary D Allen, Cassandra L Miller, Bin Dong, Jenny J Yang, Ning Fang, Angela M Mabb

Journal: Front Cell Neurosci

PubMed ID: 36998269

Doi: 10.3389/fncel.2023.1091324

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The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Authors: Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Charlotte Wallaeys, Louise Nuyttens, Joyca De Temmerman, Tino Hochepied, Sylviane Dewaele, Joke Vanden Berghe, Niek Sanders, Ben Wielockx, Rudi Beyaert, Claude Libert

Journal: Front Immunol

PubMed ID: 37006237

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Trends in the evolution of the elasmobranch melanocortin-2 receptor: Insights from structure/function studies on the activation of whale shark Mc2r

Authors: Brianne E Hoglin, Marin V Miner, Ugumuur Erbenebayar, Ciaran A Shaughnessy, Robert M Dores

Journal: Gen Comp Endocrinol

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Cryopreservation modifies the distribution of the prostate-derived lectin SL15 on the llama (Lama glama) sperm

Authors: Renato Zampini, Ximena A Castro-González, Micaela Scandura, Luciana M Sari, Ana V Diaz, Alfredo Martin, Martin E Argañaraz, Silvana A Apichela

Journal: Theriogenology

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High-force catch bonds between the Staphylococcus aureus surface protein SdrE and complement regulator factor H drive immune evasion

Authors: Telmo O Paiva, Joan A Geoghegan, Yves F Dufrêne

Journal: Commun Biol

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Programmable protein delivery with a bacterial contractile injection system

Authors: Joseph Kreitz, Mirco J Friedrich, Akash Guru, Blake Lash, Makoto Saito, Rhiannon K Macrae, Feng Zhang

Journal: Nature

PubMed ID: 36991127

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Structural basis of peptide recognition and activation of endothelin receptors

Authors: Yujie Ji, Jia Duan, Qingning Yuan, Xinheng He, Gong Yang, Shengnan Zhu, Kai Wu, Wen Hu, Tianyu Gao, Xi Cheng, Hualiang Jiang, H Eric Xu, Yi Jiang

Journal: Nat Commun

PubMed ID: 36882417

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Development of an efficient method for selection of stable cell pools for protein expression and surface display with Expi293F cells

Authors: Chuan Chen, Zening Wang, Zehua Sun, Wei Li, Dimiter S Dimitrov

Journal: Cell Biochem Funct

PubMed ID: 36864545

Doi: 10.1002/cbf.3787

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JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension

Authors: Chen Zhang, Yue Sun, Yingying Guo, Jingjing Xu, Haiyan Zhao

Journal: Cell Death Discov

PubMed ID: 36934091

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Relative role of border restrictions, case finding and contact tracing in controlling SARS-CoV-2 in the presence of undetected transmission: a mathematical modelling study

Authors: Rachael Pung, Hannah E Clapham, Timothy W Russell, Vernon J Lee, Adam J Kucharski

Journal: BMC Med

PubMed ID: 36927576

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The proprotein convertase SKI-1/S1P is a critical host factor for Nairobi sheep disease virus infectivity

Authors: Caroline Bost, Julia Hartlaub, Vinícius Pinho Dos Reis, Thomas Strecker, Nabil G Seidah, Martin H Groschup, Sandra Diederich, Kerstin Fischer

Journal: Virus Res

PubMed ID: 36948228

Doi: 10.1016/j.virusres.2023.199099

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Rare Catechol--methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets

Authors: Fia B Larsen, Matteo Cagiada, Jonas Dideriksen, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

Journal: Biochemistry

PubMed ID: 36976271

Doi: 10.1021/acs.biochem.3c00008

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Nanotopographic micro-nano forces finely tune the conformation of macrophage mechanosensitive membrane protein integrin β to manipulate inflammatory responses

Authors: Yuanlong Guo, Yong Ao, Chen Ye, Ruidi Xia, Jiaomei Mi, Zhengjie Shan, Mengru Shi, Lv Xie, Zetao Chen

Journal: Nano Res

PubMed ID: 37359074

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Cytokinin-responsive MdTCP17 interacts with MdWOX11 to repress adventitious root primordium formation in apple rootstocks

Authors: Jiangping Mao, Chundong Niu, Ke Li, Li Fan, Zhimin Liu, Shaohuan Li, Doudou Ma, Muhammad Mobeen Tahir, Libo Xing, Caiping Zhao, Juanjuan Ma, Na An, Mingyu Han, Xiaolin Ren, Dong Zhang

Journal: Plant Cell

PubMed ID: 36544357

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Uman-type neurofilament light antibodies are effective reagents for the imaging of neurodegeneration

Authors: Gerry Shaw, Irina Madorsky, Ying Li, YongSheng Wang, Marda Jorgensen, Sabhya Rana, David D Fuller

Journal: Brain Commun

PubMed ID: 37091583

Doi: 10.1093/braincomms/fcad067

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Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective

Authors: Przemyslaw Grygier, Katarzyna Pustelny, Jakub Nowak, Przemyslaw Golik, Grzegorz M Popowicz, Oliver Plettenburg, Grzegorz Dubin, Filipe Menezes, Anna Czarna

Journal: J Med Chem

PubMed ID: 36883902

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Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity

Authors: Tong Han, Xujun Wang, Sailing Shi, Wubing Zhang, Jue Wang, Qiu Wu, Ziyi Li, Jingxin Fu, Rongbin Zheng, Jiamin Zhang, Qin Tang, Peng Zhang, Chenfei Wang

Journal: cancer immunology research

PubMed ID: 36629846

Doi: 10.1158/2326-6066.CIR-22-0056

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Structural basis for motilin and erythromycin recognition by motilin receptor

Authors: Chongzhao You, Yumu Zhang, Youwei Xu, Peiyu Xu, Zhen Li, Huadong Li, Sijie Huang, Zecai Chen, Jingru Li, H Eric Xu, Yi Jiang

Journal: Science Advances

PubMed ID: 36921049

Doi: 10.1126/sciadv.ade9020

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Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins

Authors: Shuang Zhang, Sheng-Li Ming, Lei Zeng, Lu-Fang Wang, Chao Zhang, He-Shui Zhu, Guo-Yu Yang, Gai-Ping Zhang, Bei-Bei Chu, Jiang Wang

Journal: J Med Virol

PubMed ID: 36807585

Doi: 10.1002/jmv.28591

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Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine

Authors: Jane Qin, Ju Hyeong Jeon, Jiangsheng Xu, Laura Katherine Langston, Ramesh Marasini, Stephanie Mou, Brian Montoya, Carolina R Melo-Silva, Hyo Jin Jeon, Tianyi Zhu, Luis J Sigal, Renhuan Xu, Huabin Zhu

Journal: Front Immunol

PubMed ID: 37033973

Doi: 10.3389/fimmu.2023.1126392

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Entropy-driven assisted T7 RNA polymerase amplification-activated CRISPR/Cas13a activity for SARS-CoV-2 detection in human pharyngeal swabs and environment by an electrochemiluminescence biosensor

Authors: Jihua Wei, Zichun Song, Jiuying Cui, Yuanxun Gong, Qianli Tang, Kai Zhang, Xinlei Song, Xianjiu Liao

Journal: J Hazard Mater

PubMed ID: 36965355

Doi: 10.1016/j.jhazmat.2023.131268

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Exploring the structural basis to develop efficient multi-epitope vaccines displaying interaction with HLA and TAP and TLR3 molecules to prevent NIPAH infection, a global threat to human health

Authors: Sukrit Srivastava, Sonia Verma, Mohit Kamthania, Ajay Kumar Saxena, Kailash C Pandey, Veena Pande, Michael Kolbe

Journal: PLoS ONE

PubMed ID: 36920996

Doi: 10.1371/journal.pone.0282580

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A short-chain carbonyl reductase mutant is an efficient catalyst in the production of (R)-1,3-butanediol

Authors: Xiaoyan Guo, Yunfang Gao, Fangzheng Liu, Yong Tao, Haibo Jin, Jianjun Wang, Sheng Wu

Journal: Microb Biotechnol

PubMed ID: 36946330

Doi: 10.1111/1751-7915.14249

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Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge

Authors: Ebony N Gary, Nicholas J Tursi, Bryce M Warner, Gina Cuismano, Jennifer Connors, Elizabeth M Parzych, Bryan D Griffin, Matthew R Bell, Ali R Ali, Drew Frase, Casey E Hojecki, Gabriela A Canziani, Irwin Chaiken, Toshitha Kannan, Estella Moffat, Carissa Embury-Hyatt, Sarah K Wooton, Andrew Kossenkov, Ami Patel, Darwyn Kobasa, Michele A Kutzler, Elias K Haddad, David B Weiner

Journal: Front Immunol

PubMed ID: 36999023

Doi: 10.3389/fimmu.2023.1138609

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A chemically controlled Cas9 switch enables temporal modulation of diverse effectors

Authors: Cindy T Wei, Nicholas A Popp, Omri Peleg, Rachel L Powell, Elhanan Borenstein, Dustin J Maly, Douglas M Fowler

Journal: Nat Chem Biol

PubMed ID: 36879061

Doi: 10.1038/s41589-023-01278-6

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