客户发表文献

至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 36/513 每页显示数量

DAB2IP-knocking down resulted in radio-resistance of breast cancer cells is associated with increased hypoxia and vasculogenic mimicry formation

Authors: Xiangyan Zhang, Quanxin Wang, Ruiqi Zhang, Zhaolu Kong

Journal: Int J Radiat Biol

PubMed ID: 36947637

Doi: 10.1080/09553002.2023.2194390

Products & Services: Proteins, Expression, Isolation and Analysis

Increasing lysergic acid levels for ergot alkaloid biosynthesis: Directing catalysis the F-G loop of Clavine oxidases

Authors: Li Rong Lim, Garrett Wong, Maybelle K Go, Wen Shan Yew

Journal: Front Microbiol

PubMed ID: 37007471

Doi: 10.3389/fmicb.2023.1150937

Products & Services: Proteins, Expression, Isolation and Analysis

Integrating biopolymer design with physical unclonable functions for anticounterfeiting and product traceability in agriculture

Authors: Hui Sun, Saurav Maji, Anantha P Chandrakasan, Benedetto Marelli

Journal: Sci Adv

PubMed ID: 36947609

Doi: 10.1126/sciadv.adf1978

Products & Services: Peptide Synthesis

Phase I Trial of a Therapeutic DNA Vaccine for Preventing Hepatocellular Carcinoma from Chronic Hepatitis C Virus (HCV) Infection

Authors: Jeffrey M Jacobson, David Zahrieh, Carrie A Strand, Marcia Cruz-Correa, Surakit Pungpapong, Lewis R Roberts, Sumithra J Mandrekar, Luz Maria Rodriguez, Jean Boyer, Idania Marrero, Kimberly A Kraynyak, Matthew P Morrow, Albert J Sylvester, Jan M Pawlicki, Elisabeth Gillespie, Eduardo Barranco, Ellen Richmond, Asad Umar, David B Weiner, Paul J Limburg

Journal: Cancer Prev Res (Phila)

PubMed ID: 36534786

Doi: 10.1158/1940-6207.CAPR-22-0217

Products & Services: Peptide Synthesis

Preclinical evaluation of immunogenicity, efficacy and safety of a recombinant plant-based SARS-CoV-2 RBD vaccine formulated with 3M-052-Alum adjuvant

Authors: Waranyoo Phoolcharoen, Balamurugan Shanmugaraj, Narach Khorattanakulchai, Piyanate Sunyakumthorn, Sathit Pichyangkul, Pornnarin Taepavarapruk, Wanlapa Praserthsee, Suchinda Malaivijitnond, Suwimon Manopwisedjaroen, Arunee Thitithanyanont, Kanjana Srisutthisamphan, Anan Jongkaewwattana, Mark Tomai, Christopher B Fox, Suthira Taychakhoonavudh

Journal: Vaccine

PubMed ID: 36963999

Doi: 10.1016/j.vaccine.2023.03.027

Products & Services: Insect Expression

Bispecific antibodies combine breadth, potency, and avidity of parental antibodies to neutralize sarbecoviruses

Authors: Laura Radić, Kwinten Sliepen, Victor Yin, Mitch Brinkkemper, Joan Capella-Pujol, Angela I Schriek, Jonathan L Torres, Sandhya Bangaru, Judith A Burger, Meliawati Poniman, Ilja Bontjer, Joey H Bouhuijs, David Gideonse, Dirk Eggink, Andrew B Ward, Albert J R Heck, Marit J Van Gils, Rogier W Sanders, Janke Schinkel

Journal: iScience

PubMed ID: 37063468

Doi: 10.1016/j.isci.2023.106540

Products & Services: Recombinant Proteins

Cloning, characterization, and heterologous expression of a candidate Hirudin gene from the salivary gland transcriptome of Hirudo nipponia

Authors: Ping Shi, Jian Wei, Huajian You, Shijiang Chen, Fayin Tan, Zenghui Lu

Journal: Sci Rep

PubMed ID: 36973525

Doi: 10.1038/s41598-023-32303-2

Products & Services: Proteins, Expression, Isolation and Analysis

Process development and characterization of recombinant nucleocapsid protein for its application on COVID-19 diagnosis

Authors: Luãnna Elisa Liebscher Vidal, Janaina Figueira-Mansur, Patrícia Barbosa Jurgilas, Ana Paula Correa Argondizzo, Cristiane Pinheiro Pestana, Fernanda Otaviano Martins, Haroldo Cid da Silva Junior, Mariana Miguez, Bernardo Oliveira Loureiro, Christiane de Fátima Silva Marques, Karen Soares Trinta, Leila Botelho Rodrigues da Silva, Marcelle Bral de Mello, Edimilson Domingos da Silva, Renata Chagas Bastos, Gabriela Esteves

Journal: Protein Expr Purif

PubMed ID: 36921810

Doi: 10.1016/j.pep.2023.106263

Products & Services: Molecular Biology Reagents

JNK Activation in Alzheimer's Disease Is Driven by Amyloid β and Is Associated with Tau Pathology

Authors: Maite Solas, Silvia Vela, Cristian Smerdou, Eva Martisova, Iván Martínez-Valbuena, María-Rosario Luquin, María J Ramírez

Journal: ACS Chem Neurosci

PubMed ID: 36976903

Doi: 10.1021/acschemneuro.3c00093

Products & Services: Proteins, Expression, Isolation and Analysis

IL-10-providing B cells govern pro-inflammatory activity of macrophages and microglia in CNS autoimmunity

Authors: Anastasia Geladaris, Silke Häusser-Kinzel, Roxanne Pretzsch, Nitzan Nissimov, Klaus Lehmann-Horn, Darius Häusler, Martin S Weber

Journal: Acta Neuropathol

PubMed ID: 36854993

Doi: 10.1007/s00401-023-02552-6

Products & Services: Proteins, Expression, Isolation and Analysis

IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway

Authors: Juan Gao, Shiqi Suo, Jingxia Li, Chunxia Wang, Ranran Deng, Yuxia Hu, Chunzheng Zhang

Journal: Exp Ther Med

PubMed ID: 37006880

Doi: 10.3892/etm.2023.11868

Products & Services: Proteins, Expression, Isolation and Analysis

miR-126 mitigates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting the ERK1/2 and Bcl-2 pathways

Authors: Ying Zhang, Yiping Dong, Qiushi Wei, Zhikun Zhuang, Youwen Liu, Qiang Yuan, Wei He, Zhenhao Jing, Jitian Li, Peifeng Li, Leilei Zhang, Zhinan Hong, Ning Zhang, Haibin Wang, Wuyin Li

Journal: Acta Biochim Biophys Sin (Shanghai)

PubMed ID: 36942990

Doi: 10.3724/abbs.2023016

Products & Services: Proteins, Expression, Isolation and Analysis

Immunoglobulin G subclasses confer protection against bloodstream dissemination through distinct mechanisms in mouse models

Authors: Xinhai Chen, Haley Gula, Tonu Pius, Chong Ou, Margaryta Gomozkova, Lai-Xi Wang, Olaf Schneewind, Dominique Missiakas

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36972444

Doi: 10.1073/pnas.2220765120

Products & Services: Proteins, Expression, Isolation and Analysis

Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases

Authors: George D Lampe, Rebeca T King, Tyler S Halpin-Healy, Sanne E Klompe, Marcus I Hogan, Phuc Leo H Vo, Stephen Tang, Alejandro Chavez, Samuel H Sternberg

Journal: biorxiv

PubMed ID: 36993517

Doi: 10.1101/2023.03.17.533036

Products & Services: Molecular Biology Reagents

KRT5 mutation regulate melanin metabolism through notch signalling pathway between keratinocytes and melanocytes

Authors: Weixue Jia, Yuanyuan Zhang, Xue Wang, Lingling Luo, Heng Sun, Yiqun Jiang, Jianbo Wang, Qiuxia Mao, Youming Guo, Lingzhuo Kong, Ran Mo, Chengrang Li

Journal: Exp Dermatol

PubMed ID: 36809573

Doi: 10.1111/exd.14761

Products & Services: Molecular Biology Reagents

Conservation and divergence of flg22, pep1 and nlp20 in activation of immune response and inhibition of root development

Authors: Yan Huang, Junmei Cui, Meng Li, Rongqian Yang, Yang Hu, Xiaosong Yu, Ying Chen, Qiqi Wu, Huipeng Yao, Guozhi Yu, Jinya Guo, Huaiyu Zhang, Shuang Wu, Yi Cai

Journal: Plant Sci

PubMed ID: 36963637

Doi: 10.1016/j.plantsci.2023.111686

Products & Services: Peptide Synthesis

The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma

Authors: Lucia Morgado-Palacin, Jessie A Brown, Thomas F Martinez, Juana M Garcia-Pedrero, Farhad Forouhar, S Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodriguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F Fernandez, Mario F Fraga, Arianna L Kim, Jorge Santos-Juanes, David M Owens, Juan P Rodrigo, Alan Saghatelian, Adolfo A Ferrando

Journal: Nat Commun

PubMed ID: 36899004

Doi: 10.1038/s41467-023-36713-8

Products & Services: DNA Sequencing

Colorectal cancer-derived extracellular vesicles containing HSP70 enhance macrophage phagocytosis by up-regulating MARCO expression

Authors: Yu Sun, Wenjun Xiao, Yang Yu, Yuchen Jiang, Zhijie Xiao, Defa Huang, Tianyu Zhong, Jiang Li, Xi Xiang, Yulong He, Zhigang Li

Journal: Exp Cell Res

PubMed ID: 36958650

Doi: 10.1016/j.yexcr.2023.113565

Products & Services: Gene Synthesis

Anti-human immunodeficiency virus-1 activity of MoMo30 protein isolated from the traditional African medicinal plant Momordica balsamina

Authors: Mahfuz Khan, Amad Diop, Erick Gbodossou, Peng Xiao, Morgan Coleman, Kenya De Barros, Hao Duong, Vincent C Bond, Virginia Floyd, Kofi Kondwani, Valerie Montgomery Rice, Sandra Harris-Hooker, Francois Villinger, Michael D Powell

Journal: Virol J

PubMed ID: 36949470

Doi: 10.1186/s12985-023-02010-5

Products & Services: Molecular Biology Reagents

Identification of tagged glycans with a protein nanopore

Authors: Minmin Li, Yuting Xiong, Yuchen Cao, Chen Zhang, Yuting Li, Hanwen Ning, Fan Liu, Han Zhou, Xiaonong Li, Xianlong Ye, Yue Pang, Jiaming Zhang, Xinmiao Liang, Guangyan Qing

Journal: Nat Commun

PubMed ID: 36977665

Doi: 10.1038/s41467-023-37348-5

Products & Services: Codon Optimization

Nuclease activity of Plasmodium falciparum Alba family protein PfAlba3

Authors: Chinmoy Banerjee, Shiladitya Nag, Manish Goyal, Debanjan Saha, Asim Azhar Siddiqui, Somnath Mazumder, Subhashis Debsharma, Saikat Pramanik, Uday Bandyopadhyay

Journal: Cell Rep

PubMed ID: 36947546

Doi: 10.1016/j.celrep.2023.112292

Arc ubiquitination regulates endoplasmic reticulum-mediated Ca release and CaMKII signaling

Authors: Mohammad A Ghane, Wei Wei, Dina W Yakout, Zachary D Allen, Cassandra L Miller, Bin Dong, Jenny J Yang, Ning Fang, Angela M Mabb

Journal: Front Cell Neurosci

PubMed ID: 36998269

Doi: 10.3389/fncel.2023.1091324

Products & Services: Proteins, Expression, Isolation and Analysis

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Authors: Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Charlotte Wallaeys, Louise Nuyttens, Joyca De Temmerman, Tino Hochepied, Sylviane Dewaele, Joke Vanden Berghe, Niek Sanders, Ben Wielockx, Rudi Beyaert, Claude Libert

Journal: Front Immunol

PubMed ID: 37006237

Doi: 10.3389/fimmu.2023.1124011

Products & Services: Proteins, Expression, Isolation and Analysis

Trends in the evolution of the elasmobranch melanocortin-2 receptor: Insights from structure/function studies on the activation of whale shark Mc2r

Authors: Brianne E Hoglin, Marin V Miner, Ugumuur Erbenebayar, Ciaran A Shaughnessy, Robert M Dores

Journal: Gen Comp Endocrinol

PubMed ID: 36996927

Doi: 10.1016/j.ygcen.2023.114278

Products & Services: Proteins, Expression, Isolation and Analysis

Cryopreservation modifies the distribution of the prostate-derived lectin SL15 on the llama (Lama glama) sperm

Authors: Renato Zampini, Ximena A Castro-González, Micaela Scandura, Luciana M Sari, Ana V Diaz, Alfredo Martin, Martin E Argañaraz, Silvana A Apichela

Journal: Theriogenology

PubMed ID: 36933286

Doi: 10.1016/j.theriogenology.2023.03.006

Products & Services: Molecular Biology Reagents

High-force catch bonds between the Staphylococcus aureus surface protein SdrE and complement regulator factor H drive immune evasion

Authors: Telmo O Paiva, Joan A Geoghegan, Yves F Dufrêne

Journal: Commun Biol

PubMed ID: 36944849

Doi: 10.1038/s42003-023-04660-1

Products & Services: Peptide Synthesis

Programmable protein delivery with a bacterial contractile injection system

Authors: Joseph Kreitz, Mirco J Friedrich, Akash Guru, Blake Lash, Makoto Saito, Rhiannon K Macrae, Feng Zhang

Journal: Nature

PubMed ID: 36991127

Doi: 10.1038/s41586-023-05870-7

Products & Services: Gene Synthesis

Structural basis of peptide recognition and activation of endothelin receptors

Authors: Yujie Ji, Jia Duan, Qingning Yuan, Xinheng He, Gong Yang, Shengnan Zhu, Kai Wu, Wen Hu, Tianyu Gao, Xi Cheng, Hualiang Jiang, H Eric Xu, Yi Jiang

Journal: Nat Commun

PubMed ID: 36882417

Doi: 10.1038/s41467-023-36998-9

Products & Services: Custom DNA/RNA Oligos

Development of an efficient method for selection of stable cell pools for protein expression and surface display with Expi293F cells

Authors: Chuan Chen, Zening Wang, Zehua Sun, Wei Li, Dimiter S Dimitrov

Journal: Cell Biochem Funct

PubMed ID: 36864545

Doi: 10.1002/cbf.3787

Products & Services: Recombinant Proteins

JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension

Authors: Chen Zhang, Yue Sun, Yingying Guo, Jingjing Xu, Haiyan Zhao

Journal: Cell Death Discov

PubMed ID: 36934091

Doi: 10.1038/s41420-023-01390-5

Products & Services: Catalog Peptides

Relative role of border restrictions, case finding and contact tracing in controlling SARS-CoV-2 in the presence of undetected transmission: a mathematical modelling study

Authors: Rachael Pung, Hannah E Clapham, Timothy W Russell, Vernon J Lee, Adam J Kucharski

Journal: BMC Med

PubMed ID: 36927576

Doi: 10.1186/s12916-023-02802-0

Products & Services: Proteins, Expression, Isolation and Analysis

The proprotein convertase SKI-1/S1P is a critical host factor for Nairobi sheep disease virus infectivity

Authors: Caroline Bost, Julia Hartlaub, Vinícius Pinho Dos Reis, Thomas Strecker, Nabil G Seidah, Martin H Groschup, Sandra Diederich, Kerstin Fischer

Journal: Virus Res

PubMed ID: 36948228

Doi: 10.1016/j.virusres.2023.199099

Products & Services: Proteins, Expression, Isolation and Analysis

Rare Catechol--methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets

Authors: Fia B Larsen, Matteo Cagiada, Jonas Dideriksen, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

Journal: Biochemistry

PubMed ID: 36976271

Doi: 10.1021/acs.biochem.3c00008

Products & Services: Proteins, Expression, Isolation and Analysis

Nanotopographic micro-nano forces finely tune the conformation of macrophage mechanosensitive membrane protein integrin β to manipulate inflammatory responses

Authors: Yuanlong Guo, Yong Ao, Chen Ye, Ruidi Xia, Jiaomei Mi, Zhengjie Shan, Mengru Shi, Lv Xie, Zetao Chen

Journal: Nano Res

PubMed ID: 37359074

Doi: 10.1007/s12274-023-5550-0

Products & Services: Proteins, Expression, Isolation and Analysis

Cytokinin-responsive MdTCP17 interacts with MdWOX11 to repress adventitious root primordium formation in apple rootstocks

Authors: Jiangping Mao, Chundong Niu, Ke Li, Li Fan, Zhimin Liu, Shaohuan Li, Doudou Ma, Muhammad Mobeen Tahir, Libo Xing, Caiping Zhao, Juanjuan Ma, Na An, Mingyu Han, Xiaolin Ren, Dong Zhang

Journal: Plant Cell

PubMed ID: 36544357

Doi: 10.1093/plcell/koac369

Products & Services: Monoclonal Antibody Services

Uman-type neurofilament light antibodies are effective reagents for the imaging of neurodegeneration

Authors: Gerry Shaw, Irina Madorsky, Ying Li, YongSheng Wang, Marda Jorgensen, Sabhya Rana, David D Fuller

Journal: Brain Commun

PubMed ID: 37091583

Doi: 10.1093/braincomms/fcad067

Products & Services: Proteins, Expression, Isolation and Analysis

Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective

Authors: Przemyslaw Grygier, Katarzyna Pustelny, Jakub Nowak, Przemyslaw Golik, Grzegorz M Popowicz, Oliver Plettenburg, Grzegorz Dubin, Filipe Menezes, Anna Czarna

Journal: J Med Chem

PubMed ID: 36883902

Doi: 10.1021/acs.jmedchem.2c01887

Products & Services: Combinatorial DNA Libraries

Structural basis for motilin and erythromycin recognition by motilin receptor

Authors: Chongzhao You, Yumu Zhang, Youwei Xu, Peiyu Xu, Zhen Li, Huadong Li, Sijie Huang, Zecai Chen, Jingru Li, H Eric Xu, Yi Jiang

Journal: Science Advances

PubMed ID: 36921049

Doi: 10.1126/sciadv.ade9020

Products & Services: Peptide Synthesis

Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity

Authors: Tong Han, Xujun Wang, Sailing Shi, Wubing Zhang, Jue Wang, Qiu Wu, Ziyi Li, Jingxin Fu, Rongbin Zheng, Jiamin Zhang, Qin Tang, Peng Zhang, Chenfei Wang

Journal: cancer immunology research

PubMed ID: 36629846

Doi: 10.1158/2326-6066.CIR-22-0056

Products & Services: SurePAGE??, Bis-Tris, 10x8, 4-12%, 15 wells SurePAGE??, Bis-Tris, 10x8, 4-12%, 15 wells Sample (MOPS Buffer)

Plasticity in airway smooth muscle differentiation during mouse lung development

Authors: Katharine Goodwin, Bezia Lemma, Pengfei Zhang, Adam Boukind, Celeste M Nelson

Journal: Dev Cell

PubMed ID: 36868232

Doi: 10.1016/j.devcel.2023.02.002

Products & Services: Proteins, Expression, Isolation and Analysis

Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine

Authors: Jane Qin, Ju Hyeong Jeon, Jiangsheng Xu, Laura Katherine Langston, Ramesh Marasini, Stephanie Mou, Brian Montoya, Carolina R Melo-Silva, Hyo Jin Jeon, Tianyi Zhu, Luis J Sigal, Renhuan Xu, Huabin Zhu

Journal: Front Immunol

PubMed ID: 37033973

Doi: 10.3389/fimmu.2023.1126392

Products & Services: Peptide Synthesis

Mapping the conformational landscape of the stimulatory heterotrimeric G protein

Authors: Shuya Kate Huang, Louis-Philippe Picard, Rima S M Rahmatullah, Aditya Pandey, Ned Van Eps, Roger K Sunahara, Oliver P Ernst, Adnan Sljoka, R Scott Prosser

Journal: Nat Struct Mol Biol

PubMed ID: 36997760

Doi: 10.1038/s41594-023-00957-1

Products & Services: Molecular Biology Reagents

Structure-activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor

Authors: Yufang Deng, Claudia V Perez Almeria, Lieke van Gijzel, Kay Schaller, Line Vedel, David E Gloriam, Trond Ulven, Hans Bräuner-Osborne

Journal: Basic Clin Pharmacol Toxicol

PubMed ID: 36930875

Doi: 10.1111/bcpt.13861

Products & Services: Molecular Biology Reagents

Vimentin Is an Attachment Receptor for Mycoplasma pneumoniae P1 Protein

Authors: Kailan Peng, Yating Liao, Xia Li, Dongdong Zeng, Youyuan Ye, Li Chen, Zhuo Zeng, Yanhua Zeng

Journal: Microbiol Spectr

PubMed ID: 36912679

Doi: 10.1128/spectrum.04489-22

Products & Services: Molecular Biology Reagents

Human immunoglobulin gene allelic variation impacts germline-targeting vaccine priming

Authors: Allan C deCamp, Martin M Corcoran, William J Fulp, Jordan R Willis, Christopher A Cottrell, Daniel L V Bader, Oleksandr Kalyuzhniy, David J Leggat, Kristen W Cohen, Ollivier Hyrien, Sergey Menis, Greg Finak, Lamar Ballweber-Fleming, Abhinaya Srikanth, Jason R Plyler, Farhad Rahaman, Angela Lombardo, Vincent Philiponis, Rachael E Whaley, Aaron Seese, Joshua Brand, Alexis M Ruppel, Wesley Hoyland, Celia R Mahoney, Alberto Cagigi, Alison Taylor, David M Brown, David R Ambrozak, Troy Sincomb, Tina-Marie Mullen, Janine Maenza, Orpheus Kolokythas, Nadia Khati, Jeffrey Bethony, Mario Roederer, David Diemert, Richard A Koup, Dagna S Laufer, Juliana M McElrath, Adrian B McDermott, Gunilla B Karlsson Hedestam, William R Schief

Journal: medrxiv

PubMed ID: 36993183

Doi: 10.1101/2023.03.10.23287126

Products & Services: Molecular Biology Reagents

Impact of homologous and heterologous boosters in neutralizing antibodies titers against SARS-CoV-2 Omicron in solid-organ transplant recipients

Authors: Aracelly Gaete-Argel, Vicente Saavedra-Alarcón, Denis Sauré, Luis Alonso-Palomares, Mónica L Acevedo, Marion Alarcón, Susan M Bueno, Alexis M Kalergis, Ricardo Soto-Rifo, Fernando Valiente-Echeverría, Claudia P Cortes

Journal: Front Immunol

PubMed ID: 36999018

Doi: 10.3389/fimmu.2023.1135478

Products & Services: Molecular Biology Reagents

A short-chain carbonyl reductase mutant is an efficient catalyst in the production of (R)-1,3-butanediol

Authors: Xiaoyan Guo, Yunfang Gao, Fangzheng Liu, Yong Tao, Haibo Jin, Jianjun Wang, Sheng Wu

Journal: Microb Biotechnol

PubMed ID: 36946330

Doi: 10.1111/1751-7915.14249

Products & Services: Molecular Biology Reagents

Production of neutralizing antibody fragment variants in the cytoplasm of E coli for rapid screening: SARS-CoV-2 a case study

Authors: Aatir A Tungekar, Rosario Recacha, Lloyd W Ruddock

Journal: Sci Rep

PubMed ID: 36927743

Doi: 10.1038/s41598-023-31369-2

Products & Services: Molecular Biology Reagents

Identification of specific and shared epitopes at the extreme N-terminal VP1 of Coxsackievirus A4, A2 and A5 by monoclonal antibodies

Authors: Yu-Xuan Tian, Wei-Ping Jin, Zhen-Ni Wei, Shi-Yun Lv, Meng-Jun Wang, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Shuo Shen

Journal: Virus Res

PubMed ID: 36805409

Doi: 10.1016/j.virusres.2023.199074

Products & Services: Peptide Synthesis

PF-D-Trimer, a protective SARS-CoV-2 subunit vaccine: immunogenicity and application

Authors: Zhihao Zhang, Jinhu Zhou, Peng Ni, Bing Hu, Normand Jolicoeur, Shuang Deng, Qian Xiao, Qian He, Gai Li, Yan Xia, Mei Liu, Cong Wang, Zhizheng Fang, Nan Xia, Zhe-Rui Zhang, Bo Zhang, Kun Cai, Yan Xu, Binlei Liu

Journal: npj Vaccines

PubMed ID: 36922524

Doi: 10.1038/s41541-023-00636-8

Products & Services: Gene Synthesis

Fine-tuning Bacterial Cyclic di-AMP Production for Durable Antitumor Effects Through the Activation of the STING Pathway

Authors: Yu Jiang, Xiyuan Li, Fenghui Qian, Bingbing Sun, Xiyuan Wang, Yan Zhang, Deqiang Zhang, Meiyu Geng, Zuoquan Xie, Sheng Yang

Journal: Research (Wash D C)

PubMed ID: 37011280

Doi: 10.34133/research.0102

Products & Services: Gene Synthesis

The diurnal salivary glands transcriptome of Dermacentor nuttalli from the first four days of blood feeding

Authors: Hejia Ma, Yanjun Lao, Susu Liu, Jingkai Ai, Xue Sun, Wei Zhang, Ming Kang, Jixu Li, Yali Sun

Journal: Ticks Tick Borne Dis

PubMed ID: 37001418

Doi: 10.1016/j.ttbdis.2023.102178

Products & Services: PCR Cloning and Subcloning

Ferulic Acid Alleviates Hepatic Lipid Accumulation and Inflammation by Improving Proximal and Distal Intestinal Barriers in NAFLD Mice

Authors: Jiaojiao Fu, Jingyan Yang, Liying He, Caixia Yang, Jing He, Yanan Hua, Jinlin Guo, Sijing Liu

Journal: Tohoku J Exp Med

PubMed ID: 36927682

Doi: 10.1620/tjem.2023.J023

Products & Services: Molecular Biology Reagents

Urease of Aspergillus fumigatus Is Required for Survival in Macrophages and Virulence

Authors: Zhenzhen Xiong, Nan Zhang, Liru Xu, Zhiduo Deng, Jarukitt Limwachiranon, Yaojie Guo, Yi Han, Wei Yang, Daniel H Scharf

Journal: Microbiol Spectr

PubMed ID: 36916906

Doi: 10.1128/spectrum.03508-22

Products & Services: Proteins, Expression, Isolation and Analysis

Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases

Authors: George D Lampe, Rebeca T King, Tyler S Halpin-Healy, Sanne E Klompe, Marcus I Hogan, Phuc Leo H Vo, Stephen Tang, Alejandro Chavez, Samuel H Sternberg

Journal: Nat Biotechnol

PubMed ID: 36991112

Doi: 10.1038/s41587-023-01748-1

Products & Services: Gene Synthesis

Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins

Authors: Shuang Zhang, Sheng-Li Ming, Lei Zeng, Lu-Fang Wang, Chao Zhang, He-Shui Zhu, Guo-Yu Yang, Gai-Ping Zhang, Bei-Bei Chu, Jiang Wang

Journal: J Med Virol

PubMed ID: 36807585

Doi: 10.1002/jmv.28591

Products & Services: Proteins, Expression, Isolation and Analysis

Novel multi-epitope vaccine against bovine brucellosis: approach from immunoinformatics to expression

Authors: Somayyeh Rahimnahal, Shahnaz Yousefizadeh, Yahya Mohammadi

Journal: J Biomol Struct Dyn

PubMed ID: 36927475

Doi: 10.1080/07391102.2023.2188962

Products & Services: Proteins, Expression, Isolation and Analysis

Entropy-driven assisted T7 RNA polymerase amplification-activated CRISPR/Cas13a activity for SARS-CoV-2 detection in human pharyngeal swabs and environment by an electrochemiluminescence biosensor

Authors: Jihua Wei, Zichun Song, Jiuying Cui, Yuanxun Gong, Qianli Tang, Kai Zhang, Xinlei Song, Xianjiu Liao

Journal: J Hazard Mater

PubMed ID: 36965355

Doi: 10.1016/j.jhazmat.2023.131268

Products & Services: Proteins, Expression, Isolation and Analysis

Exploring the structural basis to develop efficient multi-epitope vaccines displaying interaction with HLA and TAP and TLR3 molecules to prevent NIPAH infection, a global threat to human health

Authors: Sukrit Srivastava, Sonia Verma, Mohit Kamthania, Ajay Kumar Saxena, Kailash C Pandey, Veena Pande, Michael Kolbe

Journal: PLoS ONE

PubMed ID: 36920996

Doi: 10.1371/journal.pone.0282580

Products & Services: Proteins, Expression, Isolation and Analysis

Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge

Authors: Ebony N Gary, Nicholas J Tursi, Bryce M Warner, Gina Cuismano, Jennifer Connors, Elizabeth M Parzych, Bryan D Griffin, Matthew R Bell, Ali R Ali, Drew Frase, Casey E Hojecki, Gabriela A Canziani, Irwin Chaiken, Toshitha Kannan, Estella Moffat, Carissa Embury-Hyatt, Sarah K Wooton, Andrew Kossenkov, Ami Patel, Darwyn Kobasa, Michele A Kutzler, Elias K Haddad, David B Weiner

Journal: Front Immunol

PubMed ID: 36999023

Doi: 10.3389/fimmu.2023.1138609

Products & Services: Molecular Biology Reagents

Active Site Aromatic Residues Play a Dual Role in the Substrate Interaction and Protein Structure in Functional Dimers of CYP121A1 of

Authors: Christopher S Campomizzi, Amit Kumar, Patil Pranita Uttamrao, Jack J Stallone, George E Ghanatios, Thenmalarchelvi Rathinavelan, D Fernando Estrada

Journal: ACS Infect Dis

PubMed ID: 36976833

Doi: 10.1021/acsinfecdis.2c00531

Products & Services: Proteins, Expression, Isolation and Analysis

High Autophagy Patterns in Swelling Platelets During Apheresis Platelet Storage

Authors: Lu Yu, Shifang Yu, Yunlei He, Gang Deng, Qiang Li

Journal: Indian J Hematol Blood Transfus

PubMed ID: 37790743

Doi: 10.1007/s12288-023-01638-1

Products & Services: Proteins, Expression, Isolation and Analysis

A chemically controlled Cas9 switch enables temporal modulation of diverse effectors

Authors: Cindy T Wei, Nicholas A Popp, Omri Peleg, Rachel L Powell, Elhanan Borenstein, Dustin J Maly, Douglas M Fowler

Journal: Nat Chem Biol

PubMed ID: 36879061

Doi: 10.1038/s41589-023-01278-6

Products & Services: Codon Optimization

Antitumor effect of neoantigen-reactive T cells combined with PD1 inhibitor therapy in mouse lung cancer

Authors: Huan Qin, Haiyan Hu, Ximing Liao, Pei Zhao, Wenjuan He, Xiaoping Su, Jiaxing Sun, Qiang Li

Journal: J Cancer Res Clin Oncol

PubMed ID: 36933035

Doi: 10.1007/s00432-023-04683-5

Products & Services: Peptide Synthesis

Authors: Sarah Temmam, Xavier Montagutelli, Cécile Herate, Flora Donati, Béatrice Regnault, Mikael Attia, Eduard Baquero Salazar, Delphine Chretien, Laurine Conquet, Grégory Jouvion, Juliana Pipoli Da Fonseca, Thomas Cokelaer, Faustine Amara, Francis Relouzat, Thibaut Naninck, Julien Lemaitre, Nathalie Derreudre-Bosquet, Quentin Pascal, Massimiliano Bonomi, Thomas Bigot, Sandie Munier, Felix A Rey, Roger Le Grand, Sylvie van der Werf, Marc Eloit

Journal: EMBO Rep

PubMed ID: 36876574

Doi: 10.15252/embr.202256055

Products & Services: Recombinant Proteins

Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

Authors: Thayne H Dickey, Rui Ma, Sachy Orr-Gonzalez, Tarik Ouahes, Palak Patel, Holly McAleese, Brandi Butler, Elizabeth Eudy, Brett Eaton, Michael Murphy, Jennifer L Kwan, Nichole D Salinas, Michael R Holbrook, Lynn E Lambert, Niraj H Tolia

Journal: Cell Rep

PubMed ID: 36943870

Doi: 10.1016/j.celrep.2023.112266

Products & Services: Recombinant Proteins

On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation

Authors: Niying Chua, Yee Hwa Wong, Abbas El Sahili, Chuan Fa Liu, Julien Lescar

Journal: FEBS Open Bio

PubMed ID: 36788723

Doi: 10.1002/2211-5463.13575

Products & Services: Peptide Synthesis

RHINO restricts MMEJ activity to mitosis

Authors: Alessandra Brambati, Olivia Sacco, Sarina Porcella, Joshua Heyza, Mike Kareh, Jens C Schmidt, Agnel Sfeir

Journal: biorxiv

PubMed ID: 36993461

Doi: 10.1101/2023.03.16.532763

Products & Services: Recombinant Proteins

Myosin-X recruits lamellipodin to filopodia tips

Authors: Ana Popović, Mitro Miihkinen, Sujan Ghimire, Rafael Saup, Max L B Grönloh, Neil J Ball, Benjamin T Goult, Johanna Ivaska, Guillaume Jacquemet

Journal: J Cell Sci

PubMed ID: 36861887

Doi: 10.1242/jcs.260574

Products & Services: Gene Synthesis

Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders

Authors: Elżbieta Wątor , Piotr Wilk , Artur Biela, Michał Rawski , Krzysztof M Zak, Wieland Steinchen , Gert Bange, Sebastian Glatt , Przemysław Grudnik

Journal: Nature Communications

PubMed ID: 36973244

Doi: 10.1038/s41467-023-37305-2

Products & Services: Gene Synthesis Gene Synthesis

Genome-wide identification and characterization of tomato 14–3-3 (SlTFT) genes and functional analysis of SlTFT6 under heat stress

Authors: Yunfei Liang, Fang Ma, Ruili Zhang, Wenyu Li, Jiao Dang, Huai Su, Boyu Li, Tixu Hu, Mingke Zhang, Yan Liang, Xiangqiang Zhan

Journal: Physiologia plantarum

PubMed ID: 36906839

Doi: 10.1111/ppl.13888

Products & Services: Transient Expression(INACTIVE)

A riboswitch separated from its ribosome-binding site still regulates translation

Authors: Griffin M Schroeder, Olayinka Akinyemi, Jeffrey Malik, Caroline M Focht, Elizabeth M Pritchett, Cameron D Baker, James P McSally, Jermaine L Jenkins, David H Mathews, Joseph E Wedekind

Journal: Nucleic Acids Research

PubMed ID: 36762498

Doi: 10.1093/nar/gkad056.

Products & Services: Gene Synthesis

A swapped genetic code prevents viral infections and gene transfer

Authors: Akos Nyerges, Svenja Vinke, Regan Flynn, Siân V Owen, Eleanor A Rand, Bogdan Budnik, Eric Keen, Kamesh Narasimhan, Jorge A Marchand, Maximilien Baas-Thomas, Min Liu, Kangming Chen, Anush Chiappino-Pepe, Fangxiang Hu, Michael Baym, George M Church

Journal: Nature

PubMed ID: 36922599

Doi: 10.1038/s41586-023-05824-z

Products & Services: Gene Synthesis

Engineered production of isoprene from the model green microalga Chlamydomonas reinhardtii

Authors: Razan Z Yahya, Gordon B Wellman, Sebastian Overmans, Kyle J Lauersen

Journal: Metab Eng Commun .

PubMed ID: 37006831

Doi: 10.1016/j.mec.2023.e00221

Products & Services: Gene Synthesis

Epinecidin-1, a marine antifungal peptide, inhibits Botrytis cinerea and delays gray mold in postharvest peaches

Authors: Li Fan , Yingying Wei , Yi Chen , Shu Jiang , Feng Xu , Chundan Zhang , Hongfei Wang , Xingfeng Shao

Journal: Food Chem .

PubMed ID: 36191421

Doi: 10.1016/j.foodchem.2022.134419

Products & Services: Peptide Synthesis

The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite development within the tsetse vector

Authors: Aitor Casas-Sanchez, Raghavendran Ramaswamy, Samïrah Perally, Lee R Haines, Clair Rose, Marcela Aguilera-Flores, Susana Portillo, Margot Verbeelen, Shahid Hussain, Laura Smithson, Cristina Yunta, Michael J Lehane, Sue Vaughan, Jan van den Abbeele, Igor C Almeida, Martin J Boulanger, Álvaro Acosta-Serrano

Journal: PLoS Pathog

PubMed ID: 36996244

Doi: 10.1371/journal.ppat.1011269

Products & Services: Proteins, Expression, Isolation and Analysis

To Explore the Binding Affinity of Human γ-Secretase Activating Protein (GSAP) Isoform 4 with APP-C99 Peptides

Authors: Deekshi Angira, Sonali Chaudhary, Arumugam Abiramasundari, Vijay Thiruvenkatam

Journal: ACS Omega

PubMed ID: 37065030

Doi: 10.1021/acsomega.3c01117

Products & Services: Proteins, Expression, Isolation and Analysis

Peptides that Mimic RS repeats modulate phase separation of SRSF1, revealing a reliance on combined stacking and electrostatic interactions

Authors: Talia Fargason, Naiduwadura Ivon Upekala De Silva, Erin King, Zihan Zhang, Trenton Paul, Jamal Shariq, Steve Zaharias, Jun Zhang

Journal: Elife

PubMed ID: 36862748

Doi: 10.7554/eLife.84412

Products & Services: Molecular Biology Reagents

Virus-like Magnetic Mesoporous Silica Particles as a Universal Vaccination Platform against Pathogenic Infections

Authors: Mingyang Liu, Yan Zhao, Zhishang Shi, Jeffrey I Zink, Qilin Yu

Journal: ACS Nano

PubMed ID: 36961475

Doi: 10.1021/acsnano.3c00644

Products & Services: Gene Synthesis

Interaction of SARS-CoV-2 Nucleocapsid Protein and Human RNA Helicases DDX1 and DDX3X Modulates Their Activities on Double-Stranded RNA

Authors: Camilla Lodola, Massimiliano Secchi, Virginia Sinigiani, Antonella De Palma, Rossana Rossi, Davide Perico, Pier Luigi Mauri, Giovanni Maga

Journal: Int J Mol Sci

PubMed ID: 36982856

Doi: 10.3390/ijms24065784

Products & Services: Plasmid DNA Preparation

Genetically engineered CXCR4-modified exosomes for delivery of miR-126 mimics to macrophages alleviate periodontitis

Authors: Haotian Luo, Danying Chen, Ruoyu Li, Runze Li, Yungshan Teng, Yang Cao, Xuenong Zou, Weicai Wang, Chen Zhou

Journal: J Nanobiotechnology

PubMed ID: 36991451

Doi: 10.1186/s12951-023-01863-w

Products & Services: Proteins, Expression, Isolation and Analysis

Mucus-penetrating nonviral gene vaccine processed in the epithelium for inducing advanced vaginal mucosal immune responses

Authors: Qunjie Bi, Xu Song, Yangyang Zhao, Xueyi Hu, Huan Yang, Rongrong Jin, Yu Nie

Journal: Acta Pharmacuetica Sinica.B

PubMed ID: 36970203

Doi: 10.1016/j.apsb.2022.11.004

Products & Services: Peptide Synthesis

Development and Evaluation of Recombinant B-Cell Multi-Epitopes of PDHA1 and GAPDH as Subunit Vaccines against Infection in Flounder ()

Authors: Xiuzhen Sheng, Honghua Zhang, Min Liu, Xiaoqian Tang, Jing Xing, Heng Chi, Wenbin Zhan

Journal: Vaccines (Basel)

PubMed ID: 36992208

Doi: 10.3390/vaccines11030624

Products & Services: Peptide Synthesis

Purification and biochemical characterization of a novel chitosanase cloned from the gene of Kitasatospora setae KM-6054 and its application in the production of chitooligosaccharides

Authors: Yinxiao Xu, Hui Wang, Benwei Zhu, Zhong Yao, Ling Jiang

Journal: World J Microbiol Biotechnol

PubMed ID: 36905451

Doi: 10.1007/s11274-023-03561-z

Products & Services: Proteins, Expression, Isolation and Analysis

Regenerative marine waste towards CaCO nanoformulation for Alzheimer's therapy

Authors: Prakashkumar Nallasamy, Beema Shafreen Rajamohamed, Jeyakanthan Jeyaraman, Brindhadevi Kathirvel, Suganthy Natarajan

Journal: Environ Res

PubMed ID: 36889568

Doi: 10.1016/j.envres.2023.115631

Products & Services: Peptide Synthesis

Enhanced Endosomal Signaling and Desensitization of GLP-1R vs GIPR in Pancreatic Beta Cells

Authors: Yusman Manchanda, Stavroula Bitsi, Shiqian Chen, Johannes Broichhagen, Jorge Bernardino de la Serna, Ben Jones, Alejandra Tomas

Journal: Endocrinology

PubMed ID: 36774542

Doi: 10.1210/endocr/bqad028

Products & Services: Molecular Biology Reagents

DELLA functions evolved by rewiring of associated transcriptional networks

Authors: Asier Briones-Moreno, Jorge Hernández-García, Carlos Vargas-Chávez, Noel Blanco-Touriñán, Alexandros Phokas, Cristina Úrbez, Pablo D Cerdán, Juliet C Coates, David Alabadí, Miguel A Blázquez

Journal: Nat Plants

PubMed ID: 36914897

Doi: 10.1038/s41477-023-01372-6

Products & Services: Gene Synthesis

Identification of Three Human POLH Germline Variants Defective in Complementing the UV- and Cisplatin-Sensitivity of POLH-Deficient Cells

Authors: Mina Yeom, Jin-Kyung Hong, Joo-Ho Shin, Yunjong Lee, Frederick Peter Guengerich, Jeong-Yun Choi

Journal: Int J Mol Sci

PubMed ID: 36982269

Doi: 10.3390/ijms24065198

Products & Services: Custom DNA/RNA Oligos

The Influence of Protein Charge and Molecular Weight on the Affinity of Aptamers

Authors: Alissa Drees, Tung Lam Trinh, Markus Fischer

Journal: Pharmaceuticals (Basel)

PubMed ID: 36986556

Doi: 10.3390/ph16030457

Products & Services: Custom DNA/RNA Oligos

Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex

Authors: Peng Liu, Tian Xie, Xinyue Wu, Gongshe Han, Sita D Gupta, Zike Zhang, Jian Yue, Feitong Dong, Kenneth Gable, Somashekarappa Niranjanakumari, Wanyuan Li, Lin Wang, Wenchen Liu, Ruifeng Yao, Edgar B Cahoon, Teresa M Dunn, Xin Gong

Journal: SCIENCE ADVANCES

PubMed ID: 36989369

Doi: 10.1126/sciadv.adg0728

Products & Services: Proteins, Expression, Isolation and Analysis

New insights underlying the early events of dopaminergic dysfunction in Parkinson’s Disease

Authors: Hannah L. Dela Cruz, Esther L. Dela Cruz, Cody J. Zurhellen, Herbert T. York, Jim A. Baun, Joshua L. Dela Cruz, Jay S. Dela Cruz

Journal: biorxiv

Doi: 10.1101/2020.09.27.313957

Products & Services: Endotoxin Detection & Removal System

Fabrication of bFGF/polydopamine-loaded PEEK implants for improving soft tissue integration by upregulating Wnt/β-catenin signaling

Authors: Xiaohu Wang, Ning Ma, Li Feng, Mingkui Shen, Yaqi Zhou, Xinan Zhang, Ruichao Huang, Li Zhou, Shanfeng Ji, Yongli Lou, Zhi Zhu

Journal: Heliyon

PubMed ID: 37012909

Doi: 10.1016/j.heliyon.2023.e14800

Products & Services: Proteins, Expression, Isolation and Analysis

Highly Sensitive and Selective Detection of Inorganic Phosphates in the Water Environment by Biosensors Based on Bioluminescence Resonance Energy Transfer

Authors: Jie Yu, Yan Zhang, Yanping Zhao, Xuxiang Zhang, Hongqiang Ren

Journal: Anal Chem

PubMed ID: 36942460

Doi: 10.1021/acs.analchem.2c04748

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of Filamin A Mechanobinding Partner III: SAV1 Specifically Interacts with Filamin A Mechanosensitive Domain 21

Authors: Huaguan Zhang, Zhenfeng Mao, Ziwei Yang, Fumihiko Nakamura

Journal: Biochemistry

PubMed ID: 36857526

Doi: 10.1021/acs.biochem.2c00665

Products & Services: Molecular Biology Reagents

Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment

Authors: Christine McInnis, Shilpa Bhatia, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Ann Marie Egloff, Lakshmi Srinivasan, Daniel C Pregibon, Anthony J Coyle, Glenn J Hanna

Journal: J Immunother Cancer

PubMed ID: 36990508

Doi: 10.1136/jitc-2023-006721

Products & Services: Peptide Synthesis

Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants

Authors: Bin Ju, Qi Zhang, Ziyi Wang, Zhen Qin Aw, Peng Chen, Bing Zhou, Ruoke Wang, Xiangyang Ge, Qining Lv, Lin Cheng, Rui Zhang, Yi Hao Wong, Huixin Chen, Haiyan Wang, Sisi Shan, Xuejiao Liao, Xuanling Shi, Lei Liu, Justin Jang Hann Chu, Xinquan Wang, Zheng Zhang, Linqi Zhang

Journal: Nat Immunol

PubMed ID: 36914890

Doi: 10.1038/s41590-023-01449-6

Products & Services: DNA Sequencing

Dissection of Antibody Responses of Gam-COVID-Vac-Vaccinated Subjects Suggests Involvement of Epitopes Outside RBD in SARS-CoV-2 Neutralization

Authors: Maria Byazrova, Pia Gattinger, Ekaterina Astakhova, Gerhard Hofer, Musa Khaitov, Alexander Filatov, Rudolf Valenta

Journal: Int J Mol Sci

PubMed ID: 36982183

Doi: 10.3390/ijms24065104

Products & Services: Recombinant Antibody Expression

The force-dependent filamin A-G3BP1 interaction regulates phase-separated stress granule formation

Authors: Ziyi Feng, Zhenfeng Mao, Ziwei Yang, Xiaowei Liu, Fumihiko Nakamura