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A Ferritin Nanoparticle-Based Zika Virus Vaccine Candidate Induces Robust Humoral and Cellular Immune Responses and Protects Mice from Lethal Virus Challenge

Authors: Aryamav Pattnaik, Bikash R Sahoo, Lucas R Struble, Gloria E O Borgstahl, You Zhou, Rodrigo Franco, Raul G Barletta, Fernando A Osorio, Thomas M Petro, Asit K Pattnaik

Journal: Vaccines (Basel)

PubMed ID: 37112733

Doi: 10.3390/vaccines11040821

Products & Services: Gene Synthesis

8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells

Authors: Dianbao Zhang, Yunmei Fu, Ying Liu, Yifan Wu, Jiayu Chen, Luting Zhang, Rui Wang, Zaixing Chen, Tao Liu

Journal: Int J Mol Sci

PubMed ID: 37175741

Doi: 10.3390/ijms24098039

Products & Services: Molecular Biology Reagents

Porcine Deltacoronavirus-like Particles Produced by a Single Recombinant Baculovirus Elicit Virus-Specific Immune Responses in Mice

Authors: Yangkun Liu, Xueying Han, Yaqi Qiao, Tiejun Wang, Lunguang Yao

Journal: Viruses

PubMed ID: 37243181

Doi: 10.3390/v15051095

Products & Services: Molecular Biology Reagents

Mellitin peptide quantification in seasonally collected crude bee venom and its anticancer effects on myelogenous K562 human leukaemia cell line

Authors: Maher Obeidat, Ihab F Al-Khraisat, Da'san M M Jaradat, Bayan Y Ghanim, Qasem M Abdallah, Duaa Abu Arqoub, Duaa Sabbah, Ola M Al-Sanabra, Tawfiq Arafat, Nidal A Qinna

Journal: BMC Complement Med Ther

PubMed ID: 37098530

Doi: 10.1186/s12906-023-03897-x

Products & Services: DNA Sequencing

Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils

Authors: Einav Tayeb-Fligelman, Jeannette T Bowler, Christen E Tai, Michael R Sawaya, Yi Xiao Jiang, Gustavo Garcia, Sarah L Griner, Xinyi Cheng, Lukasz Salwinski, Liisa Lutter, Paul M Seidler, Jiahui Lu, Gregory M Rosenberg, Ke Hou, Romany Abskharon, Hope Pan, Chih-Te Zee, David R Boyer, Yan Li, Daniel H Anderson, Kevin A Murray, Genesis Falcon, Duilio Cascio, Lorena Saelices, Robert Damoiseaux, Vaithilingaraja Arumugaswami, Feng Guo, David S Eisenberg

Journal: Nat Commun

PubMed ID: 37185252

Doi: 10.1038/s41467-023-37865-3

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Authors: Xiaofan Jia, Fran Dong, Laura Pyle, Aaron W Michels, Liping Yu, Marian Rewers

Journal: Diabetes Technol Ther

PubMed ID: 36989496

Doi: 10.1089/dia.2023.0016

Vitamin D-binding protein in plasma microglia-derived extracellular vesicles as a potential biomarker for major depressive disorder

Authors: Gaojia Zhang, Ling Li, Yan Kong, Dandan Xu, Yu Bao, Zhiting Zhang, Zhixiang Liao, Jiao Jiao, Dandan Fan, Xiaojing Long, Ji Dai, Chunming Xie, Zhiqiang Meng, Zhijun Zhang

Journal: Genes Dis

PubMed ID: 37692510

Doi: 10.1016/j.gendis.2023.02.049

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A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation

Authors: Chiara Acchioni, Marta Acchioni, Flavia Mancini, Antonello Amendola, Giulia Marsili, Valentina Tirelli, Chin Piaw Gwee, Kitti Wing-Ki Chan, Silvia Sandini, Monica Bisbocci, Mohamed Mysara, Mahmoud ElHefnawi, Massimo Sanchez, Giulietta Venturi, Maria Letizia Barreca, Giuseppe Manfroni, Alberto Bresciani, Subhash G Vasudevan, Marco Sgarbanti

Journal: Virology

PubMed ID: 37060797

Doi: 10.1016/j.virol.2023.03.016

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IL11 signaling mediates piR-2158 suppression of cell stemness and angiogenesis in breast cancer

Authors: Qian Zhao, Lu Qian, Yuefan Guo, Jinhui Lü, Danni Li, Heying Xie, Qiong Wang, Wenjing Ma, Pengfei Liu, Yu Liu, Tao Wang, Xuebiao Wu, Junyi Han, Zuoren Yu

Journal: Theranostics

PubMed ID: 37153732

Doi: 10.7150/thno.82538

Products & Services: Proteins, Expression, Isolation and Analysis

Discovery of Lactomodulin, a Unique Microbiome-Derived Peptide That Exhibits Dual Anti-Inflammatory and Antimicrobial Activity against Multidrug-Resistant Pathogens

Authors: Walaa K Mousa, Rose Ghemrawi, Tareq Abu-Izneid, Azza Ramadan, Farah Al-Marzooq

Journal: Int J Mol Sci

PubMed ID: 37108065

Doi: 10.3390/ijms24086901

Products & Services: Molecular Biology Reagents

Design, synthesis, and biological evaluation of novel napabucasin-melatonin hybrids as potent STAT3 inhibitors

Authors: Chong Zhang, Limin Yang, Xiaojuan Yang, Qinghe Gao, Yan Qu, Liqiang Wu

Journal: Bioorg Chem

PubMed ID: 37062104

Doi: 10.1016/j.bioorg.2023.106541

Products & Services: Molecular Biology Reagents

Development and Evaluation of a Competitive Enzyme-Linked Immunosorbent Assay Based on Swine Monoclonal Antibodies for Detecting Neutralizing Antibodies against Senecavirus A

Authors: Xueqing Ma, Jiaxin Huang, Kun Li, Kailu Ding, Yuanfang Fu, Jing Zhang, Zhixun Zhao, Pinghua Li, Xingwen Bai, Dong Li, Xia Liu, Qiaoying Zeng, Zaixin Liu, Pu Sun, Zengjun Lu

Journal: Microbiol Spectr

PubMed ID: 37036366

Doi: 10.1128/spectrum.04599-22

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Expansion of circulating stem-like CD8 T cells by adding CD122-directed IL-2 complexes to radiation and anti-PD1 therapies in mice

Authors: Kateryna Onyshchenko, Ren Luo, Elena Guffart, Simone Gaedicke, Anca-Ligia Grosu, Elke Firat, Gabriele Niedermann

Journal: Nat Commun

PubMed ID: 37045833

Doi: 10.1038/s41467-023-37825-x

Products & Services: Molecular Biology Reagents

The functional and evolutionary impacts of human-specific deletions in conserved elements

Authors: James R Xue, Ava Mackay-Smith, Kousuke Mouri, Meilin Fernandez Garcia, Michael X Dong, Jared F Akers, Mark Noble, Xue Li, Kerstin Lindblad-Toh, Elinor K Karlsson, James P Noonan, Terence D Capellini, Kristen J Brennand, Ryan Tewhey, Pardis C Sabeti, Steven K Reilly

Journal: Science

PubMed ID: 37104592

Doi: 10.1126/science.abn2253

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Water Cannot Activate Traps of the Carnivorous Sundew Plant : On the Trail of Darwin's 150-Years-Old Mystery

Authors: Andrej Pavlovič, Ondřej Vrobel, Petr Tarkowski

Journal: Plants (Basel)

PubMed ID: 37176877

Doi: 10.3390/plants12091820

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ICOR: improving codon optimization with recurrent neural networks

Authors: Rishab Jain, Aditya Jain, Elizabeth Mauro, Kevin LeShane, Douglas Densmore

Journal: BMC bioinformatics

PubMed ID: 37016283

Doi: 10.1186/s12859-023-05246-8

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A cationic motif upstream Engrailed2 homeodomain controls cell internalization through selective interaction with heparan sulfates

Authors: Sébastien Cardon, Yadira P Hervis, Gérard Bolbach, Chrystel Lopin-Bon, Jean-Claude Jacquinet, Françoise Illien, Astrid Walrant, Delphine Ravault, Bingwei He, Laura Molina, Fabienne Burlina, Olivier Lequin, Alain Joliot, Ludovic Carlier, Sandrine Sagan

Journal: Nat Commun

PubMed ID: 37032404

Doi: 10.1038/s41467-023-37757-6

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Sustained secretion of human growth hormone from TheraCyte devices encapsulated with PiggyBac-engineered retinal pigment epithelium cells

Authors: Claudia R Cecchi, Sidsel Alsing, Gustavo P P Jesus, Enio A Zacarias, Lisbeth Kjaer, Michelle S Clement, Makiko Kumagai-Braesch, Thomas J Corydon, Paolo Bartolini, Cibele N Peroni, Lars Aagaard

Journal: Tissue Cell

PubMed ID: 37087908

Doi: 10.1016/j.tice.2023.102095

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ACD-containing chaperones reveal the divergent thermo-tolerance in penaeid shrimp

Authors: Xiaoxi Zhang, Xiaojun Zhang, Jianbo Yuan, Fuhua Li

Journal: science of the total environment

PubMed ID: 37023801

Doi: 10.1016/j.scitotenv.2023.163239

Products & Services: Proteins, Expression, Isolation and Analysis

A Versatile Platform for the Tumor-Targeted Intracellular Delivery of Peptides, Proteins, and siRNA

Authors: Yifan Yang, Haichao Zhu, Dingkang Liu, Hong Luo, Ruilong Chang, Yue Ji, Wenbing Yao, Jun Yin, Xiangdong Gao

Journal: advanced fucntional materials

Doi: 10.1002/adfm.202301011

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Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease

Authors: Xiaofeng Zhang, Fenghua Yang, Xiechao Zhan , Tong Bian, Zhihan Xing, Yichen Lu, Yigong Shi

Journal: Molecular Cell

PubMed ID: 37028420

Doi: 10.1016/j.molcel.2023.03.015

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Study of NIT domain-containing chemoreceptors from two global phytopathogens and identification of NIT domains in eukaryotes

Authors: Elizabet Monteagudo-Cascales, Álvaro Ortega, Félix Velando, Bertrand Morel, Miguel A Matilla, Tino Krell

Journal: Mol Microbiol

PubMed ID: 37186477

Doi: 10.1111/mmi.15069

Products & Services: Proteins, Expression, Isolation and Analysis

Lactucin Synthase Inactivation Boosts the Accumulation of Anti-inflammatory 8-Deoxylactucin and Its Derivatives in Chicory ( L)

Authors: Katarina Cankar, Johanna Christina Hakkert, Robert Sevenier, Christina Papastolopoulou, Bert Schipper, João P Baixinho, Naiara Fernández, Melanie S Matos, Ana Teresa Serra, Claudia Nunes Santos, Khabat Vahabi, Alain Tissier, Paul Bundock, Dirk Bosch

Journal: J Agric Food Chem

PubMed ID: 37036799

Doi: 10.1021/acs.jafc.2c08959

Products & Services: Proteins, Expression, Isolation and Analysis

Kinetic characterization and phylogenetic analysis of human ADP-dependent glucokinase reveal new insights into its regulatory properties

Authors: Alejandra Herrera-Morandé, Gabriel Vallejos-Baccelliere, Pablo A Cea, Ricardo A Zamora, Dixon Cid, Pablo Maturana, Felipe González-Ordenes, Víctor Castro-Fernández, Victoria Guixé

Journal: Arch Biochem Biophys

PubMed ID: 37084804

Doi: 10.1016/j.abb.2023.109602

Products & Services: Proteins, Expression, Isolation and Analysis

Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions

Authors: He-Wei Jiang, Hong Chen, Yun-Xiao Zheng, Xue-Ning Wang, Qingfeng Meng, Jin Xie, Jiong Zhang, ChangSheng Zhang, Zhao-Wei Xu, Zi-Qing Chen, Lei Wang, Wei-Sha Kong, Kuan Zhou, Ming-Liang Ma, Hai-Nan Zhang, Shu-Juan Guo, Jun-Biao Xue, Jing-Li Hou, Zhe-Yi Liu, Wen-Xue Niu, Fang-Jun Wang, Tao Wang, Wei Li, Rui-Na Wang, Yong-Jun Dang, Daniel M Czajkowsky, JianFeng Pei, Jia-Jia Dong, Sheng-Ce Tao

Journal: Sci China Life Sci

PubMed ID: 37059927

Doi: 10.1007/s11427-023-2316-2

Products & Services: Plasmid DNA Preparation

Transcriptional regulation of autophagy by chromatin remodeling complex and histone variant

Authors: Xin Li, Shanshan Wang, Xilan Yu, Shanshan Li

Journal: Autophagy

PubMed ID: 37039545

Doi: 10.1080/15548627.2023.2200352

Products & Services: Proteins, Expression, Isolation and Analysis

Deep mutational scanning highlights a new role for cytosolic regions in Hrd1 function

Authors: Brian G Peterson, Jiwon Hwang, Jennifer E Russ, Jeremy Schroeder, Peter L Freddolino, Ryan D Baldridge

Journal: biorxiv

PubMed ID: 37066402

Doi: 10.1101/2023.04.03.535444

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Role of mechanotransduction mediated by YAP/TAZ in the treatment of neurogenic erectile dysfunction with low-intensity pulsed ultrasound

Authors: Yang Liu, Xiao-Ying Pan, Xiang-Xiang Zhang, Ji-Lei Sun, Yin-Hui Mao, Yong Yang, Zhi-Tao Wei

Journal: Andrology

PubMed ID: 37042189

Doi: 10.1111/andr.13438

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LncRNA FLAIL affects alternative splicing and represses flowering in Arabidopsis

Authors: Yu Jin, Maxim Ivanov, Anna Nelson Dittrich, Andrew Dl Nelson, Sebastian Marquardt

Journal: EMBO J

PubMed ID: 37051749

Doi: 10.15252/embj.2022110921

Products & Services: Proteins, Expression, Isolation and Analysis

The salivary chaperone protein NlDNAJB9 of Nilaparvata lugens activated plant immune responses

Authors: Haoli Gao, Xumin Lin, Xiaowei Yuan, Jianzheng Zou, Huihui Zhang, Yixi Zhang, Zewen Liu

Journal: Journal of Experimental Botany

PubMed ID: 37103882

Doi: 10.1093/jxb/erad154

Products & Services: Proteins, Expression, Isolation and Analysis

The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia

Authors: Swapnil Rohidas Shinde, David U Mick, Erika Aoki, Rachel B Rodrigues, Steven P Gygi, Maxence V Nachury

Journal: Dev Cell

PubMed ID: 37019113

Doi: 10.1016/j.devcel.2023.03.003

Products & Services: Proteins, Expression, Isolation and Analysis

Blue Native PAGE-Antibody Shift in Conjunction with Mass Spectrometry to Reveal Protein Subcomplexes: Detection of a Cerebellar α1/α6-Subunits Containing γ-Aminobutyric Acid Type A Receptor Subtype

Authors: Miao Chen, Frank Koopmans, Iryna Paliukhovich, Sophie J F van der Spek, Jian Dong, August B Smit, Ka Wan Li

Journal: Int J Mol Sci

PubMed ID: 37108794

Doi: 10.3390/ijms24087632

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Synonymous alterations of cancer-associated Trp53 CpG mutational hotspots cause fatal developmental jaw malocclusions but no tumors in knock-in mice

Authors: Richard J Epstein, Frank P Y Lin, Robert A Brink, James Blackburn

Journal: PLoS ONE

PubMed ID: 37053216

Doi: 10.1371/journal.pone.0284327

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of Ndfip1 as a novel negative regulator for spatial memory formation associated with increased ubiquitination of Beclin 1 and PTEN

Authors: Wei-Lun Hsu, Yun-Li Ma, Yan-Chu Chen, Yen-Chen Liu, Kuang-Min Cheng, Eminy H Y Lee

Journal: PLoS ONE

PubMed ID: 37023120

Doi: 10.1371/journal.pone.0283908

Products & Services: Proteins, Expression, Isolation and Analysis

Omicron BA1-specific T-cell responses in adults vaccinated with CoronaVac or BNT162b2 in Hong Kong: an observational cohort study

Authors: Chris Ka Pun Mok, Chunke Chen, Shilin Zhao, Yuanxin Sun, Karen Yiu, Tat-On Chan, Ho-Lun Lai, Kiu Cheung Lai, Ka Man Lau, Kwun Cheung Ling, Ken K P Chan, Susanna S Ng, Fanny W Ko, Malik Peiris, David S Hui

Journal: Lancet Microbe

PubMed ID: 37086735

Doi: 10.1016/S2666-5247(23)00006-X

Products & Services: Proteins, Expression, Isolation and Analysis

Immune responses to citrullinated and homocitrullinated peptides in healthy donors are not restricted to the HLA SE shared allele and can be selected into the memory pool

Authors: Ruhul H Choudhury, Ian Daniels, Poonam Vaghela, Suha Atabani, Thomas Kirk, Peter Symonds, Katherine W Cook, Abdullah Al-Omari, Daisy Weston, Sabaria Shah, David Hutchinson, Samantha J Paston, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant

Journal: Immunology

PubMed ID: 37055914

Doi: 10.1111/imm.13645

Products & Services: Proteins, Expression, Isolation and Analysis

A frame-shift mutation in COMTD1 is associated with impaired pheomelanin pigmentation in chicken

Authors: Huijuan Bi, Jonas Tranell, Dawn C Harper, Weifeng Lin, Jingyi Li, Anders R Hellström, Mårten Larsson, Carl-Johan Rubin, Chao Wang, Shumaila Sayyab, Susanne Kerje, Bertrand Bed'hom, David Gourichon, Shosuke Ito, Kazumasa Wakamatsu, Michèle Tixier-Boichard, Michael S Marks, Daniel Globisch, Leif Andersson

Journal: PLoS Genet

PubMed ID: 37068079

Doi: 10.1371/journal.pgen.1010724

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Structural and Biochemical Characterization of Zinc SufU-SufS Complex

Authors: Ingie Elchennawi, Philippe Carpentier, Christelle Caux, Marine Ponge, Sandrine Ollagnier de Choudens

Journal: Biomolecules

PubMed ID: 37238602

Doi: 10.3390/biom13050732

Products & Services: Plasmid DNA Preparation

19n01, a broadly neutralizing antibody against omicron BA1, BA2, BA4/5, and other SARS-CoV-2 variants of concern

Authors: Melissa García-Vega, Edgar A Melgoza-González, Sofía Hernández-Valenzuela, Diana Hinojosa-Trujillo, Mónica Reséndiz-Sandoval, Mara Anais Llamas-Covarrubias, Martín Loza-López, Olivia Valenzuela, Alan Soto-Gaxiola, Miguel A Hernández-Oñate, Verónica Mata-Haro, Irene Cassaniti, Josè Camilla Sammartino, Alessandro Ferrari, Luca Simonelli, Mattia Pedotti, Rui Sun, Fanglei Zuo, Fausto Baldanti, Luca Varani, Harold Marcotte, Qiang Pan-Hammarström, Jesús Hernández

Journal: iScience

PubMed ID: 37063467

Doi: 10.1016/j.isci.2023.106562

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Development of high cell density Limosilactobacillus reuteri KUB-AC5 for cell factory using oxidative stress reduction approach

Authors: Nisit Watthanasakphuban, Pimsiriya Srila, Phitsanu Pinmanee, Kamonwan Sompinit, Kittipong Rattanaporn, Clemens Peterbauer

Journal: Microb Cell Fact

PubMed ID: 37120528

Doi: 10.1186/s12934-023-02076-4

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mA epitranscriptomic regulation of tissue homeostasis during primate aging

Authors: Zeming Wu, Mingming Lu, Di Liu, Yue Shi, Jie Ren, Si Wang, Ying Jing, Sheng Zhang, Qian Zhao, Hongyu Li, Zihui Yu, Zunpeng Liu, Shijia Bi, Tuo Wei, Yun-Gui Yang, Jingfa Xiao, Juan Carlos Izpisua Belmonte, Jing Qu, Weiqi Zhang, Weimin Ci, Guang-Hui Liu

Journal: Nat Aging

PubMed ID: 37118553

Doi: 10.1038/s43587-023-00393-2

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An Orf-Virus (ORFV)-Based Vector Expressing a Consensus H1 Hemagglutinin Provides Protection against Diverse Swine Influenza Viruses

Authors: Gabriela Mansano do Nascimento, Dina Bugybayeva, Veerupaxagouda Patil, Jennifer Schrock, Ganesh Yadagiri, Gourapura J Renukaradhya, Diego G Diel

Journal: Viruses

PubMed ID: 37112974

Doi: 10.3390/v15040994

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A Silicon-Based PDMS-PEG Copolymer Microfluidic Chip for Real-Time Polymerase Chain Reaction Diagnosis

Authors: Siyu Yang, Qingyue Xian, Yiteng Liu, Ziyi Zhang, Qi Song, Yibo Gao, Weijia Wen

Journal: J Funct Biomater

PubMed ID: 37103298

Doi: 10.3390/jfb14040208

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Parasite Malate-Quinone Oxidoreductase Functionally Complements a Yeast Deletion Mutant of Mitochondrial Malate Dehydrogenase

Authors: Takeshi Ito, Sayaka Kajita, Minori Fujii, Yasuo Shinohara

Journal: Microbiol Spectr

PubMed ID: 37036365

Doi: 10.1128/spectrum.00168-23

Products & Services: Proteins, Expression, Isolation and Analysis

A replicon RNA vaccine can induce durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned

Authors: Megan A O'Connor, David W Hawman, Kimberly Meade-White, Shanna Leventhal, Wenjun Song, Samantha Randall, Jacob Archer, Thomas B Lewis, Brieann Brown, Megan N Fredericks, Kaitlin R Sprouse, Hillary C Tunggal, Mara Maughan, Naoto Iwayama, Chul Ahrens, William Garrison, Solomon Wangari, Kathryn A Guerriero, Patrick Hanley, Jamie Lovaglio, Greg Saturday, David Veesler, Paul T Edlefsen, Amit P Khandhar, Heinz Feldmann, Deborah Heydenburg Fuller, Jesse H Erasmus

Journal: PLoS Pathog

PubMed ID: 37075079

Doi: 10.1371/journal.ppat.1011298

Products & Services: Proteins, Expression, Isolation and Analysis

In Vitro FVIII-Encoding Transgenic Mesenchymal Stem Cells Maintain Successful Coagulation in FVIII-Deficient Plasma Mimicking Hemophilia A

Authors: Cansu Hemşinlioğlu, Elif Sibel Aslan, Cihan Taştan, Didem Çakırsoy, Raife Dilek Turan, Utku Seyis, Muhammer Elek, Gözde Sır Karakuş, Ömur Selin Günaydın, Selen Abanuz, Derya Dilek Kançağı, Bulut Yurtsever, Koray Yalçın, Murat Kasap, Ercüment Ovalı

Journal: Turk J Haematol

PubMed ID: 37022209

Doi: 10.4274/tjh.galenos.2023.2022-0318

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Single von Willebrand factor C-domain protein confers host defense against white spot syndrome virus by functioning as a pattern recognition receptor in Macrobrachium nipponense

Authors: Nan Qin, Muyi Li, Han Zhang, Feifei Li, Xinrui Guo, Mengjia Wu, Qingli Zhang, Ting Tang, Fengsong Liu

Journal: Int J Biol Macromol

PubMed ID: 37085073

Doi: 10.1016/j.ijbiomac.2023.124520

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Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma

Authors: Akihiro Kitagawa, Tsuyoshi Osawa, Miwa Noda, Yuta Kobayashi, Sho Aki, Yusuke Nakano, Tomoko Saito, Dai Shimizu, Hisateru Komatsu, Maki Sugaya, Junichi Takahashi, Keisuke Kosai, Seiichiro Takao, Yushi Motomura, Kuniaki Sato, Qingjiang Hu, Atsushi Fujii, Hiroaki Wakiyama, Taro Tobo, Hiroki Uchida, Keishi Sugimachi, Kohei Shibata, Tohru Utsunomiya, Shogo Kobayashi, Hideshi Ishii, Takanori Hasegawa, Takaaki Masuda, Yusuke Matsui, Atsushi Niida, Tomoyoshi Soga, Yutaka Suzuki, Satoru Miyano, Hiroyuki Aburatani, Yuichiro Doki, Hidetoshi Eguchi, Masaki Mori, Keiichi I Nakayama, Teppei Shimamura, Tatsuhiro Shibata, Koshi Mimori

Journal: Br J Cancer

PubMed ID: 37076565

Doi: 10.1038/s41416-023-02256-4

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De novo design of modular peptide-binding proteins by superhelical matching

Authors: Kejia Wu, Hua Bai, Ya-Ting Chang, Rachel Redler, Kerrie E McNally, William Sheffler, T J Brunette, Derrick R Hicks, Tomos E Morgan, Tim J Stevens, Adam Broerman, Inna Goreshnik, Michelle DeWitt, Cameron M Chow, Yihang Shen, Lance Stewart, Emmanuel Derivery, Daniel Adriano Silva, Gira Bhabha, Damian C Ekiert, David Baker

Journal: Nature

PubMed ID: 37020023

Doi: 10.1038/s41586-023-05909-9

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Identificationof a novel linear epitope on the porcine reproductive and respiratory syndrome virus nucleocapsid protein, as recognized by a specific monoclonal antibody

Authors: Yuening Cheng, Miaoli Wu, Li Xiao, Mengdi Zhang, Bihong Huang, Feng Cong, Li Yi

Journal: Front Immunol

PubMed ID: 37143683

Doi: 10.3389/fimmu.2023.1165396

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surface display of endolysin LysKB317 for control of bacterial contamination in corn ethanol fermentations

Authors: Shao-Yeh Lu, Siqing Liu, Maulik H Patel, Kristina M Glenzinski, Christopher D Skory

Journal: Front Bioeng Biotechnol

PubMed ID: 37091344

Doi: 10.3389/fbioe.2023.1162720

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CMPK2 restricts Zika virus replication by inhibiting viral translation

Authors: Joanna B Pawlak, Jack Chun-Chieh Hsu, Hongjie Xia, Patrick Han, Hee-Won Suh, Tyler L Grove, Juliet Morrison, Pei-Yong Shi, Peter Cresswell, Maudry Laurent-Rolle

Journal: PLoS Pathog

PubMed ID: 37075076

Doi: 10.1371/journal.ppat.1011286

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Binding motif for RIC-3 chaperon protein in serotonin type 3A receptors

Authors: Hoa Quynh Do, Michaela Jansen

Journal: J Gen Physiol

PubMed ID: 37026993

Doi: 10.1085/jgp.202213305

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Cotton peroxisome-localized lysophospholipase counteracts the toxic effects of Verticillium dahliae NLP1 and confers wilt resistance

Authors: Guilin Wang, Xinyu Wang, Jian Song, Haitang Wang, Chaofeng Ruan, Wenshu Zhang, Zhan Guo, Weixi Li, Wangzhen Guo

Journal: The plant journal: for cell and molecular biology

PubMed ID: 37026387

Doi: 10.1111/tpj.16236

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Pipeline to identify neoantigens exposed by radiation

Authors: Claire Lhuillier, Samantha J Van Nest, Nils-Petter Rudqvist, Sandra Demaria

Journal: Methods Cell Biol

PubMed ID: 37890930

Doi: 10.1016/bs.mcb.2023.02.010

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Development of a selection assay for small guide RNAs that drive efficient site-directed RNA editing

Authors: Juan Felipe Diaz Quiroz, Namrata Ojha, Elnur E Shayhidin, Dasuni De Silva, Jesse Dabney, Amy Lancaster, James Coull, Stuart Milstein, Andrew W Fraley, Christopher R Brown, Joshua J C Rosenthal

Journal: Nucleic Acids Res

PubMed ID: 36840708

Doi: 10.1093/nar/gkad098

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Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress

Authors: Parminder Singh Mavi, Shweta Singh, Ashwani Kumar

Journal: BMC Microbiol

PubMed ID: 37081437

Doi: 10.1186/s12866-023-02853-6

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Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence

Authors: Kathryn M Hastie, Xiaoying Yu, Fernanda Ana-Sosa-Batiz, Dawid S Zyla, Stephanie S Harkins, Chitra Hariharan, Hal Wasserman, Michelle A Zandonatti, Robyn Miller, Erin Maule, Kenneth Kim, Kristen M Valentine, Sujan Shresta, Erica Ollmann Saphire

Journal: Cell Rep

PubMed ID: 37083327

Doi: 10.1016/j.celrep.2023.112421

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Biochemical characterization of RNase R 2'-O-methylation sensitivity

Authors: Xiaolan Lu, Xiangwen Gu, Yong Li, Yifan Wu, Qiang Wang, Wenkui Yu, Qihan Chen

Journal: Biochimie

PubMed ID: 37105299

Doi: 10.1016/j.biochi.2023.04.016

Products & Services: Proteins, Expression, Isolation and Analysis

A small epitope shared by p53 and an unrelated protein upregulated after adenovirus infection

Authors: Jessica J Miciak, Fred Bunz

Journal: biorxiv

PubMed ID: 37162859

Doi: 10.1101/2023.04.28.538733

Protein-plastic interactions: The driving forces behind the high affinity of a carbohydrate-binding module for polyethylene terephthalate

Authors: Andrew Philip Rennison, Peter Westh, Marie Sofie Møller

Journal: The Science of the total environment

PubMed ID: 36739021

Doi: 10.1016/j.scitotenv.2023.161948

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A CsoR family transcriptional regulator, TTHA1953, controls the sulfur oxidation pathway in Thermus thermophilus HB8

Authors: John K Barrows, Michael W Van Dyke

Journal: The journal of biological chemistry

PubMed ID: 37116710

Doi: 10.1016/j.jbc.2023.104759

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An unexpected hydratase synthesizes the green light-absorbing pigment fucoxanthin

Authors: Tianjun Cao, Yu Bai, Paul Buschbeck, Qiaozhu Tan, Michael B Cantrell, Yinjuan Chen, Yanyou Jiang, Run-Zhou Liu, Nana K Ries, Xiaohuo Shi, Yan Sun, Maxwell A Ware, Fenghua Yang, Huan Zhang, Jichang Han, Lihan Zhang, Jing Huang, Martin Lohr, Graham Peers, Xiaobo Li

Journal: The Plant cell

PubMed ID: 37100425

Doi: 10.1093/plcell/koad116

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Evaluation of the Diagnostic Performance of Two Automated SARS-CoV-2 Neutralization Immunoassays following Two Doses of mRNA, Adenoviral Vector, and Inactivated Whole-Virus Vaccinations in COVID-19 Naïve Subjects

Authors: Eszter Csoma, Ágnes Nagy Koroknai, Renáta Sütő, Erika Szakács Szilágyi, Marianna Pócsi, Attila Nagy, Klára Bíró, János Kappelmayer, Béla Nagy

Journal: Microorganisms

PubMed ID: 37317161

Doi: 10.3390/microorganisms11051187

Products & Services: Proteins, Expression, Isolation and Analysis

Allosteric role of the citrate synthase homology domain of ATP citrate lyase

Authors: Xuepeng Wei, Kollin Schultz, Hannah L Pepper, Emily Megill, Austin Vogt, Nathaniel W Snyder, Ronen Marmorstein

Journal: Nat Commun

PubMed ID: 37076498

Doi: 10.1038/s41467-023-37986-9

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Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants

Authors: Hangtian Guo, Yixuan Yang, Tiantian Zhao, Yuchi Lu, Yan Gao, Tinghan Li, Hang Xiao, Xiaoyu Chu, Le Zheng, Wanting Li, Hao Cheng, Haibin Huang, Yang Liu, Yang Lou, Henry C Nguyen, Chao Wu, Yuxin Chen, Haitao Yang, Xiaoyun Ji

Journal: Commun Biol

PubMed ID: 37012333

Doi: 10.1038/s42003-023-04759-5

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Chemiluminescence Biosensor for the Determination of Cardiac Troponin I (cTnI)

Authors: Robert Tannenberg, Martin Paul, Bettina Röder, Santosh L Gande, Sridhar Sreeramulu, Krishna Saxena, Christian Richter, Harald Schwalbe, Claudia Swart, Michael G Weller

Journal: Biosensors (Basel)

PubMed ID: 37185530

Doi: 10.3390/bios13040455

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Identification of a Conserved, Linear Epitope on VP3 of Species Recognized by a Broad-Spectrum Monoclonal Antibody

Authors: Lie Fu, Xiao-Yu Zhang, Wei-Ping Jin, Chen Wang, Sha-Sha Qian, Meng-Jun Wang, Wen-Hui Wang, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Xiao-Qi Chen, Shuo Shen

Journal: Viruses

PubMed ID: 37113008

Doi: 10.3390/v15041028

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Screening antivirals with a mCherry-expressing recombinant bovine respiratory syncytial virus: a proof of concept using cyclopamine

Authors: Jenna Fix, Delphyne Descamps, Marie Galloux, Cécile Ferret, Edwige Bouguyon, Siamak Zohari, Katarina Näslund, Sara Hägglund, Ralf Altmeyer, Jean-François Valarcher, Sabine Riffault, Jean-François Eléouët

Journal: Vet Res

PubMed ID: 37069656

Doi: 10.1186/s13567-023-01165-x

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On the origin of appetite: GLWamide in jellyfish represents an ancestral satiety neuropeptide

Authors: Vladimiros Thoma, Shuhei Sakai, Koki Nagata, Yuu Ishii, Shinichiro Maruyama, Ayako Abe, Shu Kondo, Masakado Kawata, Shun Hamada, Ryusaku Deguchi, Hiromu Tanimoto

Journal: Proc Natl Acad Sci U S A

PubMed ID: 37011192

Doi: 10.1073/pnas.2221493120

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NMDARs control object recognition memory destabilization and reconsolidation

Authors: Janine I Rossato, Andressa Radiske, Maria Carolina Gonzalez, Gênedy Apolinário, Raquel L S de Araújo, Lia R M Bevilaqua, Martín Cammarota

Journal: Brain Res Bull

PubMed ID: 37011815

Doi: 10.1016/j.brainresbull.2023.03.013

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Functional Characterization of the Putative POT from

Authors: Hani Gharabli, Maria Rafiq, Anna Iqbal, Ruyu Yan, Nanda G Aduri, Neha Sharma, Bala K Prabhala, Osman Mirza

Journal: Biology (Basel)

PubMed ID: 37237465

Doi: 10.3390/biology12050651

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Stiffness-dependent dynamic effect of inflammation on keratocyte phenotype and differentiation

Authors: Jialin Chen 1 2 3 4, Qingyun Mo 1 2, Renwang Sheng 1 2, Qiuzi Long 2 5, Zhixuan Chen 1 2, Chuanquan Liu 1 2, Aini Zhang 1 2, Yifan Luo 1 2, Jia Liu 1 2, Wei Zhang 1 2 3 4

Journal: Biomed Mater

PubMed ID: 37068490

Doi: 10.1088/1748-605X/accda9

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Ebselen restores peri-implantitis-induced osteogenic inhibition via suppressing BMSCs ferroptosis

Authors: Ziqing Huang, Guanhui Chen, Hiokuan Wu, Xiaoqiong Huang, Ruogu Xu, Feilong Deng, Yiming Li

Journal: Exp Cell Res

PubMed ID: 37116735

Doi: 10.1016/j.yexcr.2023.113612

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Rational development of multicomponent mRNA vaccine candidates against mpox

Authors: Rong-Rong Zhang, Zheng-Jian Wang, Yi-Long Zhu, Wei Tang, Chao Zhou, Suo-Qun Zhao, Mei Wu, Tao Ming, Yong-Qiang Deng, Qi Chen, Ning-Yi Jin, Qing Ye, Xiao Li, Cheng-Feng Qin

Journal: Emerging microbes & infections

PubMed ID: 36947428

Doi: 10.1080/22221751.2023.2192815

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The TORC1 activates Rpd3L complex to deacetylate Ino80 and H2A.Z and repress autophagy

Authors: Xin Li, Qianyun Mei, Qi Yu, Min Wang, Fei He, Duncheng Xiao, Huan Liu, Feng Ge, Xilan Yu, Shanshan Li

Journal: Science Advances

PubMed ID: 36888706

Doi: 10.1126/sciadv.ade8312

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Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2

Authors: Hyung J Kwon, Jun Zhang, Matina Kosikova, Weichun Tang, Uriel Ortega-Rodriguez, Hanqin Peng, Clement A Meseda, Cyntia L Pedro, Falko Schmeisser, Jianming Lu, Insung Kang, Bin Zhou, Charles T Davis, David E Wentworth, Wilbur H Chen, Mallory C Shriver, Robin S Barnes, Marcela F Pasetti, Jerry P Weir, Bing Chen, Hang Xie

Journal: J Med Virol

PubMed ID: 36916782

Doi: 10.1002/jmv.28673

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The Zinc-BED Transcription Factor Bedwarfed Promotes Proportional Dendritic Growth and Branching through Transcriptional and Translational Regulation in

Authors: Shatabdi Bhattacharjee, Eswar Prasad R Iyer, Srividya Chandramouli Iyer, Sumit Nanda, Myurajan Rubaharan, Giorgio A Ascoli, Daniel N Cox

Journal: Int J Mol Sci

PubMed ID: 37047316

Doi: 10.3390/ijms24076344

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Comparison of Immunogenicity and Reactogenicity of Five Primary Series of COVID-19 Vaccine Regimens against Circulating SARS-CoV-2 Variants of Concern among Healthy Thai Populations

Authors: Tavitiya Sudjaritruk, Oramai Mueangmo, Jutamad Saheng, Poramed Winichakoon, Parichat Salee, Worawan Wongjak, Tanachot Chaito, Jutarat Praparattanapan, Khanuengnit Nuket, Nuttarika Solai, Jiraprapa Wipasa, Kriangkrai Chawansuntati, Romanee Chaiwarith

Journal: Vaccines (Basel)

PubMed ID: 36992147

Doi: 10.3390/vaccines11030564

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DNA accelerates the protease inhibition of a bacterial serpin chloropin

Authors: Jiawei Xu, Wei Ye, Ting Ting Yang, Teng Yan, Haiyan Cai, Aiwu Zhou, Yufeng Yang

Journal: Front Mol Biosci

PubMed ID: 37065444

Doi: 10.3389/fmolb.2023.1157186

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SWIP mediates retromer-independent membrane recruitment of the WASH complex

Authors: Vojtěch Dostál, Tereza Humhalová, Pavla Beránková, Ondřej Pácalt, Lenka Libusová

Journal: Traffic

PubMed ID: 36995008

Doi: 10.1111/tra.12884

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Re-engineering a lost trait: , a master regulator of arbuscular mycorrhizal symbiosis, affects genes for immunity and metabolism of non-host Arabidopsis when restored long after its evolutionary loss

Authors: Eli D Hornstein, Melodi Charles, Megan Franklin, Brianne Edwards, Simina Vintila, Manuel Kleiner, Heike Sederoff

Journal: biorxiv

PubMed ID: 36945518

Doi: 10.1101/2023.03.06.531368

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The NAC transcription factor ONAC083 negatively regulates rice immunity against Magnaporthe oryzae by directly activating transcription of the RING‐H2 gene OsRFPH2‐6

Authors: Yan Bi , Hui Wang , Xi Yuan , Yuqing Yan , Dayong Li , Fengming Song

Journal: J Integr Plant Biol

PubMed ID: 36308720

Doi: 10.1111/jipb.13399

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Interactions of Nanoscale Self-Assembled Peptide-Based Assemblies with Glioblastoma Cell Models and Spheroids

Authors: Charlotta G Lebedenko, Molly E Murray, Beatriz G Goncalves, Diego S Perez， Dominic J Lambo, Ipsita A Banerjee

Journal: ACS Omega

PubMed ID: 37033803

Doi: 10.1021/acsomega.2c08049

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Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein

Authors: Patrick O Byrne, Brian E Fisher, David R Ambrozak, Elizabeth G Blade, Yaroslav Tsybovsky, Barney S Graham, Jason S McLellan, Rebecca J Loomis

Journal: Nat Commun

PubMed ID: 36932063

Doi: 10.1038/s41467-023-36995-y

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DIA-based technology explores hub pathways and biomarkers of neurological recovery in ischemic stroke after rehabilitation

Authors: Wei Hu, Ping Li, Nianju Zeng, Sheng Tan

Journal: Front Neurol

PubMed ID: 36959823

Doi: 10.3389/fneur.2023.1079977

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Heterologous production of polycyclopropanated fatty acids and their methyl esters in Streptomyces

Authors: Kevin Yin, Pablo Cruz-Morales, Christopher M Whitford, Jay D Keasling

Journal: STAR Protoc

PubMed ID: 36952335

Doi: 10.1016/j.xpro.2023.102190

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Combining elicitor treatment of chitosan, methyl jasmonate, and cyclodextrin to induce the generation of immune response bioactive peptides in peanut hairy root culture

Authors: Chanyanut Pankaew, Kanitha Supdensong, Chonnikan Tothong, Sittiruk Roytrakul, Narumon Phaonakrop, Anupan Kongbangkerd, Apinun Limmongkon

Journal: Plant Sci

PubMed ID: 36914116

Doi: 10.1016/j.plantsci.2023.111670

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Molluscum Contagiosum Virus Protein MC008 Targets NF-κB Activation by Inhibiting Ubiquitination of NEMO

Authors: Thomas Phelan, Clara Lawler, Andreas Pichlmair, Mark A Little, Andrew G Bowie, Gareth Brady

Journal: J Virol

PubMed ID: 36916940

Doi: 10.1128/jvi.00108-23

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Functional SARS-CoV-2-specific T cells of donor origin in allogeneic stem cell transplant recipients of a T-cell-replete infusion: A prospective observational study

Authors: Corinna La Rosa, Flavia Chiuppesi, Yoonsuh Park, Qiao Zhou, Dongyun Yang, Ketevan Gendzekhadze, Minh Ly, Jing Li, Teodora Kaltcheva, Sandra Ortega Francisco, Miguel-Angel Gutierrez, Haris Ali, Salman Otoukesh, Idoroenyi Amanam, Amandeep Salhotra, Vinod A Pullarkat, Ibrahim Aldoss, Michael Rosenzweig, Ahmed M Aribi, Anthony S Stein, Guido Marcucci, Sanjeet Singh Dadwal, Ryotaro Nakamura, Stephen J Forman, Monzr M Al Malki, Don J Diamond

Journal: Front Immunol

PubMed ID: 36936918

Doi: 10.3389/fimmu.2023.1114131

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Process development for an effective COVID-19 vaccine candidate harboring recombinant SARS-CoV-2 delta plus receptor binding domain produced by Pichia pastoris

Authors: Sibel Kalyoncu, Semiramis Yilmaz, Ayca Zeybek Kuyucu, Dogu Sayili, Olcay Mert, Hakan Soyturk, Seyda Gullu, Huseyin Akinturk, Erhan Citak, Merve Arslan, Melda Guray Taskinarda, Ibrahim Oguzhan Tarman, Gizem Yilmazer Altun, Ceren Ozer, Ridvan Orkut, Aysegul Demirtas, Idil Tilmensagir, Umur Keles, Ceren Ulker, Gizem Aralan, Yavuz Mercan, Muge Ozkan, Hasan Onur Caglar, Gizem Arik, Mehmet Can Ucar, Muzaffer Yildirim, Tugce Canavar Yildirim, Dilara Karadag, Erhan Bal, Aybike Erdogan, Serif Senturk, Serdar Uzar, Hakan Enul, Cumhur Adiay, Fahriye Sarac, Arzu Tas Ekiz, Irem Abaci, Ozge Aksoy, Hivda Ulbegi Polat, Saban Tekin, Stefan Dimitrov, Aykut Ozkul, Gerhard Wingender, Ihsan Gursel, Mehmet Ozturk, Mehmet Inan

Journal: Sci Rep

PubMed ID: 36997624

Doi: 10.1038/s41598-023-32021-9

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Exogenous aralar/slc25a12 can replace citrin/slc25a13 as malate aspartate shuttle component in liver

Authors: Luis González-Moreno, Andrea Santamaría-Cano, Alberto Paradela, María Luz Martínez-Chantar, Miguel Á Martín, Mercedes Pérez-Carreras, Alberto García-Picazo, Jesús Vázquez, Enrique Calvo, Gloria González-Aseguinolaza, Takeyori Saheki, Araceli Del Arco, Jorgina Satrústegui, Laura Contreras

Journal: Mol Genet Metab Rep

PubMed ID: 36967723

Doi: 10.1016/j.ymgmr.2023.100967

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Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers

Authors: Pete Schmidt, Kristin Narayan, Yong Li, Chengzi I Kaku, Michael E Brown, Elizabeth Champney, James C Geoghegan, Maximiliano Vásquez, Eric M Krauland, Thomas Yockachonis, Shuangyi Bai, Bronwyn M Gunn, Anthony Cammarata, Christopher M Rubino, Paul Ambrose, Laura M Walker

Journal: Sci Transl Med

PubMed ID: 36947596

Doi: 10.1126/scitranslmed.adg2783

Products & Services: Proteins, Expression, Isolation and Analysis

Sortase A transpeptidation produces seamless, unbranched biotinylated nanobodies for multivalent and multifunctional applications

Authors: Eugene M Obeng, David L Steer, Alex J Fulcher, Kylie M Wagstaff

Journal: Nanoscale Adv

PubMed ID: 37056610

Doi: 10.1039/d3na00014a

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Recombinant Modified Vaccinia Virus Ankara Expressing a Glycosylation Mutant of Dengue Virus NS1 Induces Specific Antibody and T-Cell Responses in Mice

Authors: Lucas Wilken, Sonja Stelz, Ayse Agac, Gerd Sutter, Chittappen Kandiyil Prajeeth, Guus F Rimmelzwaan

Journal: Vaccines (Basel)

PubMed ID: 37112626

Doi: 10.3390/vaccines11040714

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Deoxyshikonin inhibited rotavirus replication by regulating autophagy and oxidative stress through SIRT1/FoxO1/Rab7 axis

Authors: Haohai Huang, Dan Liao, Bin He, Rong Pu, Yejia Cui, Guanghui Zhou

Journal: Microb Pathog

PubMed ID: 36907361

Doi: 10.1016/j.micpath.2023.106065

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Establishment and Application of Indirect ELISAs for Detecting Antibodies against Goose Astrovirus Genotype 1 and 2

Authors: Mengran Zhang, Xinyu Wei, Jing Qian, Zhengyu Yu, Xin Liu, Yan Luo, Haitao Zhang, Youfang Gu, Yin Li

Journal: Vaccines (Basel)

PubMed ID: 36992248

Doi: 10.3390/vaccines11030664

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Regulated control of virus replication by 4-hydroxytamoxifen-induced splicing

Authors: Zhenghao Zhao, Busen Wang, Shipo Wu, Zhe Zhang, Yi Chen, Jinlong Zhang, Yudong Wang, Danni Zhu, Yao Li, Jinghan Xu, Lihua Hou, Wei Chen

Journal: Front Microbiol

PubMed ID: 36992923

Doi: 10.3389/fmicb.2023.1112580

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Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train

Authors: Yuanyuan Ma, Jun He, Shaobai Li, Deqiang Yao, Chenhui Huang, Jian Wu, Ming Lei

Journal: Nat Commun

PubMed ID: 36932088

Doi: 10.1038/s41467-023-37208-2

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DNA sensing via the cGAS/STING pathway activates the immunoproteasome and adaptive T-cell immunity

Authors: Xinyuan Wang, Huabin Zhang, Yuqin Wang, Laylan Bramasole, Kai Guo, Fatima Mourtada, Thomas Meul, Qianjiang Hu, Valeria Viteri, Ilona Kammerl, Melanie Konigshoff, Mareike Lehmann, Thomas Magg, Fabian Hauck, Isis E Fernandez, Silke Meiners

Journal: EMBO J

PubMed ID: 36912165

Doi: 10.15252/embj.2022110597

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