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CD95/Fas ligand mRNA is toxic to cells through more than one mechanism

Authors: Ashley Haluck-Kangas, Madelaine Fink, Elizabeth T Bartom, Marcus E Peter

Journal: Mol Biomed

PubMed ID: 37059938

Doi: 10.1186/s43556-023-00119-1

Products & Services: Proteins, Expression, Isolation and Analysis

Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core

Authors: Peter J Carman, Grzegorz Rebowski, Roberto Dominguez, Saif S Alqassim

Journal: J Struct Biol

PubMed ID: 37028467

Doi: 10.1016/j.jsb.2023.107960

Products & Services: Proteins, Expression, Isolation and Analysis

High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo

Authors: Sebastian G Huayamares, Melissa P Lokugamage, Regina Rab, Alejandro J Da Silva Sanchez, Hyejin Kim, Afsane Radmand, David Loughrey, Liming Lian, Yuning Hou, Bhagelu R Achyut, Annette Ehrhardt, Jeong S Hong, Cory D Sago, Kalina Paunovska, Elisa Schrader Echeverri, Daryll Vanover, Philip J Santangelo, Eric J Sorscher, James E Dahlman

Journal: J Control Release

PubMed ID: 37028451

Doi: 10.1016/j.jconrel.2023.04.005

Products & Services: Proteins, Expression, Isolation and Analysis

Production of Clubroot Standards Using a Recombinant Surrogate to Overcome Natural Genetic Variability

Authors: Anjana Patel, Roy Kennedy

Journal: Plants (Basel)

PubMed ID: 37111913

Doi: 10.3390/plants12081690

Products & Services: Proteins, Expression, Isolation and Analysis

Shieldin complex assembly kinetics and DNA binding by SHLD3

Authors: Vivek Susvirkar, Alex C Faesen

Journal: Commun Biol

PubMed ID: 37031298

Doi: 10.1038/s42003-023-04757-7

Products & Services: Peptide Synthesis

Development and evaluation of an indirect ELISA using a multiepitope antigen for the diagnosis of intestinal schistosomiasis

Authors: Karine Ferreira Lopes, Mariana Lourenço Freire, Dayane Costa Souza Lima, Martin Johannes Enk, Edward Oliveira, Stefan Michael Geiger

Journal: Parasitology

PubMed ID: 37092694

Doi: 10.1017/S0031182023000409

Products & Services: Molecular Biology Reagents

Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or RORγT Associate with Bacterial Control in Granulomas

Authors: Nicole L Grant, Kristen Kelly, Pauline Maiello, Helena Abbott, Shelby O'Connor, Philana Ling Lin, Charles A Scanga, JoAnne L Flynn

Journal: MBio

PubMed ID: 37039646

Doi: 10.1128/mbio.00477-23

Products & Services: Molecular Biology Reagents

Interspecies/Intergroup Complementation of Orthotospovirus Replication and Movement through Reverse Genetics Systems

Authors: Mingfeng Feng, Minglong Chen, Yulong Yuan, Qinhai Liu, Ruixiang Cheng, Tongqing Yang, Luyao Li, Rong Guo, Yongxin Dong, Jing Chen, Yawen Yang, Yuling Yan, Hongmin Cui, Dong Jing, Jinrui Kang, Shuxian Chen, Jia Li, Min Zhu, Changjun Huang, Zhongkai Zhang, Richard Kormelink, Xiaorong Tao

Journal: J Virol

PubMed ID: 37022194

Doi: 10.1128/jvi.01809-22

Products & Services: Molecular Biology Reagents

Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway

Authors: Alexander D Fulford, Leonie Enderle, Jannette Rusch, Didier Hodzic, Maxine V Holder, Alex Earl, Robin Hyunseo Oh, Nicolas Tapon, Helen McNeill

Journal: J Cell Biol

PubMed ID: 37071483

Doi: 10.1083/jcb.202204059

Products & Services: Peptide Synthesis

Proteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells

Authors: Zhengmao Xu, Yanan Wang, Meng Sun, Yongzhi Zhou, Jie Cao, Houshuang Zhang, Xuenan Xuan, Jinlin Zhou

Journal: Parasit Vectors

PubMed ID: 37046327

Doi: 10.1186/s13071-023-05753-w

Products & Services: Recombinant Proteins

Low-grade glioma risk SNP rs11706832 is associated with type I interferon response pathway genes in cell lines

Authors: Adam Rosenbaum, Anna M Dahlin, Ulrika Andersson, Benny Björkblom, Wendy Yi-Ying Wu, Håkan Hedman, Carl Wibom, Beatrice Melin

Journal: Sci Rep

PubMed ID: 37185361

Doi: 10.1038/s41598-023-33923-4

Products & Services: Recombinant Proteins

Computational design and molecular dynamics simulations suggest the mode of substrate binding in ceramide synthases

Authors: Iris D Zelnik, Beatriz Mestre, Jonathan J Weinstein, Tamir Dingjan, Stav Izrailov, Shifra Ben-Dor, Sarel J Fleishman, Anthony H Futerman

Journal: Nat Commun

PubMed ID: 37087500

Doi: 10.1038/s41467-023-38047-x

Products & Services: Proteins, Expression, Isolation and Analysis

A Recombinant Chimeric Cedar Virus-Based Surrogate Neutralization Assay Platform for Pathogenic Henipaviruses

Authors: Moushimi Amaya, Randy Yin, Lianying Yan, Viktoriya Borisevich, Bishwo N Adhikari, Andrew Bennett, Francisco Malagon, Regina Z Cer, Kimberly A Bishop-Lilly, Antony S Dimitrov, Robert W Cross, Thomas W Geisbert, Christopher C Broder

Journal: Viruses

PubMed ID: 37243163

Doi: 10.3390/v15051077

Products & Services: Molecular Biology Reagents

A triple amplification strategy using GR-5 DNAzyme as a signal medium for ultrasensitive detection of trace Pb based on CRISPR/Cas12a empowered electrochemical biosensor

Authors: Yuanyuan Yue, Songtao Wang, Qiang Jin, Nan An, Lina Wu, He Huang

Journal: Anal Chim Acta

PubMed ID: 37225346

Doi: 10.1016/j.aca.2023.341241

Products & Services: Proteins, Expression, Isolation and Analysis

Modulatory role of copper on hIAPP aggregation and toxicity in presence of insulin

Authors: Dipanwita Roy, Narayan Chandra Maity, Sourav Kumar, Anupam Maity, Bhisma N Ratha, Ranjit Biswas, Nakul Chandra Maiti, Atin Kumar Mandal, Anirban Bhunia

Journal: Int J Biol Macromol

PubMed ID: 37088193

Doi: 10.1016/j.ijbiomac.2023.124470

Products & Services: Peptide Synthesis

Endoplasmic reticulum chaperone GRP78 participates in fluoride-induced autophagy in LS8 cells by regulating the IRE1-TRAF2-JNK pathway

Authors: Lin Zhao, Liyuan Wang, Han Wang, Tao Xi, Sijia Liu, Yang Li, Jianping Ruan, Yongqing Huang

Journal: Environ Toxicol

PubMed ID: 37070943

Doi: 10.1002/tox.23805

Products & Services: Molecular Biology Reagents

Structural basis of impaired disaggregase function in the oxidation-sensitive SKD3 mutant causing 3-methylglutaconic aciduria

Authors: Sukyeong Lee, Sang Bum Lee, Nuri Sung, Wendy W Xu, Changsoo Chang, Hyun-Eui Kim, Andre Catic, Francis T F Tsai

Journal: Nat Commun

PubMed ID: 37041140

Doi: 10.1038/s41467-023-37657-9

Products & Services: Proteins, Expression, Isolation and Analysis

Immunological characterization of a VIR protein family member (VIR-14) in Plasmodium vivax-infected subjects from different epidemiological regions in Africa and South America

Authors: Raianna F Fantin, Camila H Coelho, Anne D Berhe, Luisa M D Magalhães, Dhélio B Pereira, Nichole D Salinas, Niraj H Tolia, Chanaki Amaratunga, Seila Suon, Issaka Sagara, David L Narum, Ricardo T Fujiwara, Claudia Abejon, Antonio Campos-Neto, Patrick E Duffy, Lilian L Bueno

Journal: PLoS Negl Trop Dis

PubMed ID: 37027391

Doi: 10.1371/journal.pntd.0011229

Products & Services: Gene Synthesis

Interaction of LARP4 to filamin A mechanosensing domain regulates cell migrations

Authors: Zhenfeng Mao, Fumihiko Nakamura

Journal: Front Cell Dev Biol

PubMed ID: 37169020

Doi: 10.3389/fcell.2023.1152109

Products & Services: Proteins, Expression, Isolation and Analysis

Organization, genomic targeting, and assembly of three distinct SWI/SNF chromatin remodeling complexes in Arabidopsis

Authors: Wei Fu, Yaoguang Yu, Jie Shu , Zewang Yu, Yixiong Zhong, Tao Zhu, Zhihao Zhang, Zhenwei Liang, Yuhai Cui, Chen Chen , Chenlong Li

Journal: Plant Cell .

PubMed ID: 37062961

Doi: 10.1093/plcell/koad111

Products & Services: Proteins, Expression, Isolation and Analysis

Codon pair bias deoptimization of essential genes in infectious laryngotracheitis virus reduces protein expression

Authors: Paola K Vaz, Marzieh Armat, Carol A Hartley, Joanne M Devlin

Journal: J Gen Virol

PubMed ID: 37010948

Doi: 10.1099/jgv.0.001836

Products & Services: Molecular Biology Reagents

COVID-19 adenovirus vector vaccine induces higher interferon and pro-inflammatory responses than mRNA vaccines in human PBMCs, macrophages and moDCs

Authors: Miao Jiang, Elina Väisänen, Pekka Kolehmainen, Moona Huttunen, Seppo Ylä-Herttuala, Seppo Meri, Pamela Österlund, Ilkka Julkunen

Journal: Vaccine

PubMed ID: 37142461

Doi: 10.1016/j.vaccine.2023.04.049

Products & Services: Molecular Biology Reagents

Clinical Validation of a Colorimetric Loop-Mediated Isothermal Amplification Using a Portable Device for the Rapid Detection of SARS-CoV-2

Authors: Bruna W Raddatz, Felipe J Rabello, Rafael Benedetti, Gisleine J Steil, Louise M Imamura, Edson Y S Kim, Erika B Santiago, Luís F Hartmann, João V Predebon, Bruna M Delfino, Meri B Nogueira, Jucélia S Dos Santos, Breno G da Silva, Diego R P Nicollete, Bernardo M M de Almeida, Sergio R Rogal, Marcus V M Figueredo

Journal: Diagnostics (Basel)

PubMed ID: 37046573

Doi: 10.3390/diagnostics13071355

Products & Services: Molecular Biology Reagents

Sub-millisecond conformational dynamics of the A adenosine receptor revealed by single-molecule FRET

Authors: Ivan Maslov, Oleksandr Volkov, Polina Khorn, Philipp Orekhov, Anastasiia Gusach, Pavel Kuzmichev, Andrey Gerasimov, Aleksandra Luginina, Quinten Coucke, Andrey Bogorodskiy, Valentin Gordeliy, Simon Wanninger, Anders Barth, Alexey Mishin, Johan Hofkens, Vadim Cherezov, Thomas Gensch, Jelle Hendrix, Valentin Borshchevskiy

Journal: Commun Biol

PubMed ID: 37012383

Doi: 10.1038/s42003-023-04727-z

Products & Services: Molecular Biology Reagents

Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses

Authors: Audrey Kassardjian, Eric Sun, Jamie Sookhoo, Krithika Muthuraman, Kayluz Frias Boligan, Iga Kucharska, Edurne Rujas, Arif Jetha, Donald R Branch, Shawn Babiuk, Brian Barber, Jean-Philippe Julien

Journal: Cell Rep

PubMed ID: 37053069

Doi: 10.1016/j.celrep.2023.112391

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SLFN5-mediated chromatin dynamics sculpt higherorder DNA repair topology

Authors: Jinzhou Huang, Chenming Wu, Jake A Kloeber, Huanyao Gao, Ming Gao, Qian Zhu, Yiming Chang, Fei Zhao, Guijie Guo, Kuntian Luo, Haiming Dai, Sijia Liu, Qiru Huang, Wootae Kim, Qin Zhou, Shouhai Zhu, Zheming Wu, Xinyi Tu, Ping Yin, Min Deng, Liewei Wang, Jian Yuan, Zhenkun Lou

Journal: molecular cell

PubMed ID: 36854302

Doi: 10.1016/j.molcel.2023.02.004

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Multifunctional activity-based chemical probes for sirtuins

Authors: Chiranjeev Sharma, Dickson Donu, Alyson M Curry, Elizabeth Barton, Yana Cen

Journal: RSC Adv

PubMed ID: 37063743

Doi: 10.1039/d3ra02133e

Products & Services: Proteins, Expression, Isolation and Analysis

Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization

Authors: Mallika Sastry, Anita Changela, Jason Gorman, Kai Xu, Gwo-Yu Chuang, Chen-Hsiang Shen, Cheng Cheng, Hui Geng, Sijy O'Dell, Li Ou, Reda Rawi, Mateo Reveiz, Guillaume B E Stewart-Jones, Shuishu Wang, Baoshan Zhang, Tongqing Zhou, Andrea Biju, Michael Chambers, Xuejun Chen, Angela R Corrigan, Bob C Lin, Mark K Louder, Krisha McKee, Alexandra F Nazzari, Adam S Olia, Danealle K Parchment, Edward K Sarfo, Tyler Stephens, Jonathan Stuckey, Yaroslav Tsybovsky, Raffaello Verardi, Yiran Wang, Cheng-Yan Zheng, Yuling Chen, Nicole A Doria-Rose, Adrian B McDermott, John R Mascola, Peter D Kwong

Journal: J Virol

PubMed ID: 37098956

Doi: 10.1128/jvi.01604-22

Products & Services: Molecular Biology Reagents

H, N, C backbone and Cβ resonance assignments for UBQLN1 UBA and UBAA domains

Authors: Gwen R Buel, Xiang Chen, Olumide Kayode, Anthony Cruz, Kylie J Walters

Journal: Biomol NMR Assign

PubMed ID: 37022617

Doi: 10.1007/s12104-023-10127-5

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Enhanced Degradation of Mutant -Derived Toxic Dipeptide Repeat Proteins by 20S Proteasome Activation Results in Restoration of Proteostasis and Neuroprotection

Authors: Allison S Vanecek, Jelena Mojsilovic-Petrovic, Robert G Kalb, Jetze J Tepe

Journal: ACS Chem Neurosci

PubMed ID: 37015082

Doi: 10.1021/acschemneuro.2c00732

Products & Services: Recombinant Proteins

Salt stress-induced chloroplastic hydrogen peroxide stimulates pdTPI sulfenylation and methylglyoxal accumulation

Authors: Zheng-Wei Fu, Yu-Rui Feng, Xiang Gao, Feng Ding, Jian-Hui Li, Ting-Ting Yuan, Ying-Tang Lu

Journal: Plant Cell

PubMed ID: 36695476

Doi: 10.1093/plcell/koad019

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Direct Virus Gene Detection: A CRISPR/dCas9-Mediated Surface- Enhanced Raman Scattering Strategy with Enzyme-Catalyzed Signal Amplification

Authors: Ailing Su , Yuan Liu , Xiumian Cao , Junyi Zhao , Weiqing Xu , Chongyang Liang , Ping Li , Shuping Xu

Journal: Anal Chem .

PubMed ID: 36995921

Doi: 10.1021/acs.analchem.2c05384

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Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults

Authors: Chanchan Xiao, Zhiyao Ren , Bei Zhang , Lipeng Mao , Guodong Zhu , Lijuan Gao , Jun Su , Jiezhou Ye , Ze Long , Yue Zhu , Pengfei Chen , Xiangmeng Su , Tong Zhou , Yanhao Huang , Xiongfei Chen , Chaojun Xie , Jun Yuan , Yutian Hu , Jingshan Zheng , Zhigang Wang , Jianrong Lou , Xiang Yang , Zhiqiang Kuang , Hongyi Zhang , Pengcheng Wang , Xiaofeng Liang , Oscar Junhong Luo , Guobing Chen

Journal: Nat Aging .

PubMed ID: 37117789

Doi: 10.1038/s43587-023-00379-0

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Lactucin Synthase Inactivation Boosts the Accumulation of Anti-inflammatory 8-Deoxylactucin and Its Derivatives in Chicory ( L)

Authors: Katarina Cankar, Johanna Christina Hakkert, Robert Sevenier, Christina Papastolopoulou, Bert Schipper, João P Baixinho, Naiara Fernández, Melanie S Matos, Ana Teresa Serra, Claudia Nunes Santos, Khabat Vahabi, Alain Tissier, Paul Bundock, Dirk Bosch

Journal: J Agric Food Chem

PubMed ID: 37036799

Doi: 10.1021/acs.jafc.2c08959

Products & Services: Proteins, Expression, Isolation and Analysis

Discovery of Lactomodulin, a Unique Microbiome-Derived Peptide That Exhibits Dual Anti-Inflammatory and Antimicrobial Activity against Multidrug-Resistant Pathogens

Authors: Walaa K Mousa, Rose Ghemrawi, Tareq Abu-Izneid, Azza Ramadan, Farah Al-Marzooq

Journal: Int J Mol Sci

PubMed ID: 37108065

Doi: 10.3390/ijms24086901

Products & Services: Molecular Biology Reagents

8-Methoxyflindersine-Induced Apoptosis and Cell Cycle Disorder Involving MAPK Signaling Activation in Human Colorectal Cancer Cells

Authors: Dianbao Zhang, Yunmei Fu, Ying Liu, Yifan Wu, Jiayu Chen, Luting Zhang, Rui Wang, Zaixing Chen, Tao Liu

Journal: Int J Mol Sci

PubMed ID: 37175741

Doi: 10.3390/ijms24098039

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Design, synthesis, and biological evaluation of novel napabucasin-melatonin hybrids as potent STAT3 inhibitors

Authors: Chong Zhang, Limin Yang, Xiaojuan Yang, Qinghe Gao, Yan Qu, Liqiang Wu

Journal: Bioorg Chem

PubMed ID: 37062104

Doi: 10.1016/j.bioorg.2023.106541

Products & Services: Molecular Biology Reagents

Development and Evaluation of a Competitive Enzyme-Linked Immunosorbent Assay Based on Swine Monoclonal Antibodies for Detecting Neutralizing Antibodies against Senecavirus A

Authors: Xueqing Ma, Jiaxin Huang, Kun Li, Kailu Ding, Yuanfang Fu, Jing Zhang, Zhixun Zhao, Pinghua Li, Xingwen Bai, Dong Li, Xia Liu, Qiaoying Zeng, Zaixin Liu, Pu Sun, Zengjun Lu

Journal: Microbiol Spectr

PubMed ID: 37036366

Doi: 10.1128/spectrum.04599-22

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Water Cannot Activate Traps of the Carnivorous Sundew Plant : On the Trail of Darwin's 150-Years-Old Mystery

Authors: Andrej Pavlovič, Ondřej Vrobel, Petr Tarkowski

Journal: Plants (Basel)

PubMed ID: 37176877

Doi: 10.3390/plants12091820

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A cationic motif upstream Engrailed2 homeodomain controls cell internalization through selective interaction with heparan sulfates

Authors: Sébastien Cardon, Yadira P Hervis, Gérard Bolbach, Chrystel Lopin-Bon, Jean-Claude Jacquinet, Françoise Illien, Astrid Walrant, Delphine Ravault, Bingwei He, Laura Molina, Fabienne Burlina, Olivier Lequin, Alain Joliot, Ludovic Carlier, Sandrine Sagan

Journal: Nat Commun

PubMed ID: 37032404

Doi: 10.1038/s41467-023-37757-6

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Deep mutational scanning highlights a new role for cytosolic regions in Hrd1 function

Authors: Brian G Peterson, Jiwon Hwang, Jennifer E Russ, Jeremy Schroeder, Peter L Freddolino, Ryan D Baldridge

Journal: biorxiv

PubMed ID: 37066402

Doi: 10.1101/2023.04.03.535444

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Role of mechanotransduction mediated by YAP/TAZ in the treatment of neurogenic erectile dysfunction with low-intensity pulsed ultrasound

Authors: Yang Liu, Xiao-Ying Pan, Xiang-Xiang Zhang, Ji-Lei Sun, Yin-Hui Mao, Yong Yang, Zhi-Tao Wei

Journal: Andrology

PubMed ID: 37042189

Doi: 10.1111/andr.13438

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LncRNA FLAIL affects alternative splicing and represses flowering in Arabidopsis

Authors: Yu Jin, Maxim Ivanov, Anna Nelson Dittrich, Andrew Dl Nelson, Sebastian Marquardt

Journal: EMBO J

PubMed ID: 37051749

Doi: 10.15252/embj.2022110921

Products & Services: Proteins, Expression, Isolation and Analysis

Vitamin D-binding protein in plasma microglia-derived extracellular vesicles as a potential biomarker for major depressive disorder

Authors: Gaojia Zhang, Ling Li, Yan Kong, Dandan Xu, Yu Bao, Zhiting Zhang, Zhixiang Liao, Jiao Jiao, Dandan Fan, Xiaojing Long, Ji Dai, Chunming Xie, Zhiqiang Meng, Zhijun Zhang

Journal: Genes Dis

PubMed ID: 37692510

Doi: 10.1016/j.gendis.2023.02.049

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ACD-containing chaperones reveal the divergent thermo-tolerance in penaeid shrimp

Authors: Xiaoxi Zhang, Xiaojun Zhang, Jianbo Yuan, Fuhua Li

Journal: science of the total environment

PubMed ID: 37023801

Doi: 10.1016/j.scitotenv.2023.163239

Products & Services: Proteins, Expression, Isolation and Analysis

A Versatile Platform for the Tumor-Targeted Intracellular Delivery of Peptides, Proteins, and siRNA

Authors: Yifan Yang, Haichao Zhu, Dingkang Liu, Hong Luo, Ruilong Chang, Yue Ji, Wenbing Yao, Jun Yin, Xiangdong Gao

Journal: advanced fucntional materials

Doi: 10.1002/adfm.202301011

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Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease

Authors: Xiaofeng Zhang, Fenghua Yang, Xiechao Zhan , Tong Bian, Zhihan Xing, Yichen Lu, Yigong Shi

Journal: Molecular Cell

PubMed ID: 37028420

Doi: 10.1016/j.molcel.2023.03.015

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A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation

Authors: Chiara Acchioni, Marta Acchioni, Flavia Mancini, Antonello Amendola, Giulia Marsili, Valentina Tirelli, Chin Piaw Gwee, Kitti Wing-Ki Chan, Silvia Sandini, Monica Bisbocci, Mohamed Mysara, Mahmoud ElHefnawi, Massimo Sanchez, Giulietta Venturi, Maria Letizia Barreca, Giuseppe Manfroni, Alberto Bresciani, Subhash G Vasudevan, Marco Sgarbanti

Journal: Virology

PubMed ID: 37060797

Doi: 10.1016/j.virol.2023.03.016

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IL11 signaling mediates piR-2158 suppression of cell stemness and angiogenesis in breast cancer

Authors: Qian Zhao, Lu Qian, Yuefan Guo, Jinhui Lü, Danni Li, Heying Xie, Qiong Wang, Wenjing Ma, Pengfei Liu, Yu Liu, Tao Wang, Xuebiao Wu, Junyi Han, Zuoren Yu

Journal: Theranostics

PubMed ID: 37153732

Doi: 10.7150/thno.82538

Products & Services: Proteins, Expression, Isolation and Analysis

Kinetic characterization and phylogenetic analysis of human ADP-dependent glucokinase reveal new insights into its regulatory properties

Authors: Alejandra Herrera-Morandé, Gabriel Vallejos-Baccelliere, Pablo A Cea, Ricardo A Zamora, Dixon Cid, Pablo Maturana, Felipe González-Ordenes, Víctor Castro-Fernández, Victoria Guixé

Journal: Arch Biochem Biophys

PubMed ID: 37084804

Doi: 10.1016/j.abb.2023.109602

Products & Services: Proteins, Expression, Isolation and Analysis

Porcine Deltacoronavirus-like Particles Produced by a Single Recombinant Baculovirus Elicit Virus-Specific Immune Responses in Mice

Authors: Yangkun Liu, Xueying Han, Yaqi Qiao, Tiejun Wang, Lunguang Yao

Journal: Viruses

PubMed ID: 37243181

Doi: 10.3390/v15051095

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Expansion of circulating stem-like CD8 T cells by adding CD122-directed IL-2 complexes to radiation and anti-PD1 therapies in mice

Authors: Kateryna Onyshchenko, Ren Luo, Elena Guffart, Simone Gaedicke, Anca-Ligia Grosu, Elke Firat, Gabriele Niedermann

Journal: Nat Commun

PubMed ID: 37045833

Doi: 10.1038/s41467-023-37825-x

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Mellitin peptide quantification in seasonally collected crude bee venom and its anticancer effects on myelogenous K562 human leukaemia cell line

Authors: Maher Obeidat, Ihab F Al-Khraisat, Da'san M M Jaradat, Bayan Y Ghanim, Qasem M Abdallah, Duaa Abu Arqoub, Duaa Sabbah, Ola M Al-Sanabra, Tawfiq Arafat, Nidal A Qinna

Journal: BMC Complement Med Ther

PubMed ID: 37098530

Doi: 10.1186/s12906-023-03897-x

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The functional and evolutionary impacts of human-specific deletions in conserved elements

Authors: James R Xue, Ava Mackay-Smith, Kousuke Mouri, Meilin Fernandez Garcia, Michael X Dong, Jared F Akers, Mark Noble, Xue Li, Kerstin Lindblad-Toh, Elinor K Karlsson, James P Noonan, Terence D Capellini, Kristen J Brennand, Ryan Tewhey, Pardis C Sabeti, Steven K Reilly

Journal: Science

PubMed ID: 37104592

Doi: 10.1126/science.abn2253

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Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils

Authors: Einav Tayeb-Fligelman, Jeannette T Bowler, Christen E Tai, Michael R Sawaya, Yi Xiao Jiang, Gustavo Garcia, Sarah L Griner, Xinyi Cheng, Lukasz Salwinski, Liisa Lutter, Paul M Seidler, Jiahui Lu, Gregory M Rosenberg, Ke Hou, Romany Abskharon, Hope Pan, Chih-Te Zee, David R Boyer, Yan Li, Daniel H Anderson, Kevin A Murray, Genesis Falcon, Duilio Cascio, Lorena Saelices, Robert Damoiseaux, Vaithilingaraja Arumugaswami, Feng Guo, David S Eisenberg

Journal: Nat Commun

PubMed ID: 37185252

Doi: 10.1038/s41467-023-37865-3

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Diversity of the Gβγ complexes defines spatial and temporal bias of GPCR signaling

Authors: Ikuo Masuho , Nickolas K Skamangas , Brian S Muntean , Kirill A Martemyanov

Journal: Cell Syst .

PubMed ID: 33667409

Doi: 10.1016/j.cels.2021.02.001

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Study of NIT domain-containing chemoreceptors from two global phytopathogens and identification of NIT domains in eukaryotes

Authors: Elizabet Monteagudo-Cascales, Álvaro Ortega, Félix Velando, Bertrand Morel, Miguel A Matilla, Tino Krell

Journal: Mol Microbiol

PubMed ID: 37186477

Doi: 10.1111/mmi.15069

Products & Services: Proteins, Expression, Isolation and Analysis

Structural Insights into M1 Muscarinic Acetylcholine Receptor Signaling Bias between Gαq and β-Arrestin through BRET Assays and Molecular Docking

Authors: Dongxue Wang, Yunjin Yao, Shiqi Wang, Yifei Hou, Lanxue Zhao, Hao Wang, Hongzhuan Chen, Jianrong Xu

Journal: Int J Mol Sci

PubMed ID: 37108518

Doi: 10.3390/ijms24087356

Products & Services: Proteins, Expression, Isolation and Analysis

Melittin derived peptide-drug conjugate, M-DM1, inhibits tumor progression and induces effector cell infiltration in melanoma by targeting M2 tumor-associated macrophages

Authors: Chanmi Jeong, Jeongdong Kim, Ik-Hwan Han, Soyoung Kim, Ilseob Choi, Hongsung Kim, Jin-Hyun Jeong, Hyunsu Bae

Journal: Front Immunol

PubMed ID: 37122692

Doi: 10.3389/fimmu.2023.1178776

Products & Services: Proteins, Expression, Isolation and Analysis

A Ferritin Nanoparticle-Based Zika Virus Vaccine Candidate Induces Robust Humoral and Cellular Immune Responses and Protects Mice from Lethal Virus Challenge

Authors: Aryamav Pattnaik, Bikash R Sahoo, Lucas R Struble, Gloria E O Borgstahl, You Zhou, Rodrigo Franco, Raul G Barletta, Fernando A Osorio, Thomas M Petro, Asit K Pattnaik

Journal: Vaccines (Basel)

PubMed ID: 37112733

Doi: 10.3390/vaccines11040821

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Transcriptional regulation of autophagy by chromatin remodeling complex and histone variant

Authors: Xin Li, Shanshan Wang, Xilan Yu, Shanshan Li

Journal: Autophagy

PubMed ID: 37039545

Doi: 10.1080/15548627.2023.2200352

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ICOR: improving codon optimization with recurrent neural networks

Authors: Rishab Jain, Aditya Jain, Elizabeth Mauro, Kevin LeShane, Douglas Densmore

Journal: BMC bioinformatics

PubMed ID: 37016283

Doi: 10.1186/s12859-023-05246-8

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Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions

Authors: He-Wei Jiang, Hong Chen, Yun-Xiao Zheng, Xue-Ning Wang, Qingfeng Meng, Jin Xie, Jiong Zhang, ChangSheng Zhang, Zhao-Wei Xu, Zi-Qing Chen, Lei Wang, Wei-Sha Kong, Kuan Zhou, Ming-Liang Ma, Hai-Nan Zhang, Shu-Juan Guo, Jun-Biao Xue, Jing-Li Hou, Zhe-Yi Liu, Wen-Xue Niu, Fang-Jun Wang, Tao Wang, Wei Li, Rui-Na Wang, Yong-Jun Dang, Daniel M Czajkowsky, JianFeng Pei, Jia-Jia Dong, Sheng-Ce Tao

Journal: Sci China Life Sci

PubMed ID: 37059927

Doi: 10.1007/s11427-023-2316-2

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Authors: Xiaofan Jia, Fran Dong, Laura Pyle, Aaron W Michels, Liping Yu, Marian Rewers

Journal: Diabetes Technol Ther

PubMed ID: 36989496

Doi: 10.1089/dia.2023.0016

Sustained secretion of human growth hormone from TheraCyte devices encapsulated with PiggyBac-engineered retinal pigment epithelium cells

Authors: Claudia R Cecchi, Sidsel Alsing, Gustavo P P Jesus, Enio A Zacarias, Lisbeth Kjaer, Michelle S Clement, Makiko Kumagai-Braesch, Thomas J Corydon, Paolo Bartolini, Cibele N Peroni, Lars Aagaard

Journal: Tissue Cell

PubMed ID: 37087908

Doi: 10.1016/j.tice.2023.102095

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Identification of Ndfip1 as a novel negative regulator for spatial memory formation associated with increased ubiquitination of Beclin 1 and PTEN

Authors: Wei-Lun Hsu, Yun-Li Ma, Yan-Chu Chen, Yen-Chen Liu, Kuang-Min Cheng, Eminy H Y Lee

Journal: PLoS ONE

PubMed ID: 37023120

Doi: 10.1371/journal.pone.0283908

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Omicron BA1-specific T-cell responses in adults vaccinated with CoronaVac or BNT162b2 in Hong Kong: an observational cohort study

Authors: Chris Ka Pun Mok, Chunke Chen, Shilin Zhao, Yuanxin Sun, Karen Yiu, Tat-On Chan, Ho-Lun Lai, Kiu Cheung Lai, Ka Man Lau, Kwun Cheung Ling, Ken K P Chan, Susanna S Ng, Fanny W Ko, Malik Peiris, David S Hui

Journal: Lancet Microbe

PubMed ID: 37086735

Doi: 10.1016/S2666-5247(23)00006-X

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In Vitro FVIII-Encoding Transgenic Mesenchymal Stem Cells Maintain Successful Coagulation in FVIII-Deficient Plasma Mimicking Hemophilia A

Authors: Cansu Hemşinlioğlu, Elif Sibel Aslan, Cihan Taştan, Didem Çakırsoy, Raife Dilek Turan, Utku Seyis, Muhammer Elek, Gözde Sır Karakuş, Ömur Selin Günaydın, Selen Abanuz, Derya Dilek Kançağı, Bulut Yurtsever, Koray Yalçın, Murat Kasap, Ercüment Ovalı

Journal: Turk J Haematol

PubMed ID: 37022209

Doi: 10.4274/tjh.galenos.2023.2022-0318

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Single von Willebrand factor C-domain protein confers host defense against white spot syndrome virus by functioning as a pattern recognition receptor in Macrobrachium nipponense

Authors: Nan Qin, Muyi Li, Han Zhang, Feifei Li, Xinrui Guo, Mengjia Wu, Qingli Zhang, Ting Tang, Fengsong Liu

Journal: Int J Biol Macromol

PubMed ID: 37085073

Doi: 10.1016/j.ijbiomac.2023.124520

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Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma

Authors: Akihiro Kitagawa, Tsuyoshi Osawa, Miwa Noda, Yuta Kobayashi, Sho Aki, Yusuke Nakano, Tomoko Saito, Dai Shimizu, Hisateru Komatsu, Maki Sugaya, Junichi Takahashi, Keisuke Kosai, Seiichiro Takao, Yushi Motomura, Kuniaki Sato, Qingjiang Hu, Atsushi Fujii, Hiroaki Wakiyama, Taro Tobo, Hiroki Uchida, Keishi Sugimachi, Kohei Shibata, Tohru Utsunomiya, Shogo Kobayashi, Hideshi Ishii, Takanori Hasegawa, Takaaki Masuda, Yusuke Matsui, Atsushi Niida, Tomoyoshi Soga, Yutaka Suzuki, Satoru Miyano, Hiroyuki Aburatani, Yuichiro Doki, Hidetoshi Eguchi, Masaki Mori, Keiichi I Nakayama, Teppei Shimamura, Tatsuhiro Shibata, Koshi Mimori

Journal: Br J Cancer

PubMed ID: 37076565

Doi: 10.1038/s41416-023-02256-4

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De novo design of modular peptide-binding proteins by superhelical matching

Authors: Kejia Wu, Hua Bai, Ya-Ting Chang, Rachel Redler, Kerrie E McNally, William Sheffler, T J Brunette, Derrick R Hicks, Tomos E Morgan, Tim J Stevens, Adam Broerman, Inna Goreshnik, Michelle DeWitt, Cameron M Chow, Yihang Shen, Lance Stewart, Emmanuel Derivery, Daniel Adriano Silva, Gira Bhabha, Damian C Ekiert, David Baker

Journal: Nature

PubMed ID: 37020023

Doi: 10.1038/s41586-023-05909-9

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Identificationof a novel linear epitope on the porcine reproductive and respiratory syndrome virus nucleocapsid protein, as recognized by a specific monoclonal antibody

Authors: Yuening Cheng, Miaoli Wu, Li Xiao, Mengdi Zhang, Bihong Huang, Feng Cong, Li Yi

Journal: Front Immunol

PubMed ID: 37143683

Doi: 10.3389/fimmu.2023.1165396

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surface display of endolysin LysKB317 for control of bacterial contamination in corn ethanol fermentations

Authors: Shao-Yeh Lu, Siqing Liu, Maulik H Patel, Kristina M Glenzinski, Christopher D Skory

Journal: Front Bioeng Biotechnol

PubMed ID: 37091344

Doi: 10.3389/fbioe.2023.1162720

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CMPK2 restricts Zika virus replication by inhibiting viral translation

Authors: Joanna B Pawlak, Jack Chun-Chieh Hsu, Hongjie Xia, Patrick Han, Hee-Won Suh, Tyler L Grove, Juliet Morrison, Pei-Yong Shi, Peter Cresswell, Maudry Laurent-Rolle

Journal: PLoS Pathog

PubMed ID: 37075076

Doi: 10.1371/journal.ppat.1011286

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Binding motif for RIC-3 chaperon protein in serotonin type 3A receptors

Authors: Hoa Quynh Do, Michaela Jansen

Journal: J Gen Physiol

PubMed ID: 37026993

Doi: 10.1085/jgp.202213305

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The salivary chaperone protein NlDNAJB9 of Nilaparvata lugens activated plant immune responses

Authors: Haoli Gao, Xumin Lin, Xiaowei Yuan, Jianzheng Zou, Huihui Zhang, Yixi Zhang, Zewen Liu

Journal: Journal of Experimental Botany

PubMed ID: 37103882

Doi: 10.1093/jxb/erad154

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Blue Native PAGE-Antibody Shift in Conjunction with Mass Spectrometry to Reveal Protein Subcomplexes: Detection of a Cerebellar α1/α6-Subunits Containing γ-Aminobutyric Acid Type A Receptor Subtype

Authors: Miao Chen, Frank Koopmans, Iryna Paliukhovich, Sophie J F van der Spek, Jian Dong, August B Smit, Ka Wan Li

Journal: Int J Mol Sci

PubMed ID: 37108794

Doi: 10.3390/ijms24087632

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The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia

Authors: Swapnil Rohidas Shinde, David U Mick, Erika Aoki, Rachel B Rodrigues, Steven P Gygi, Maxence V Nachury

Journal: Dev Cell

PubMed ID: 37019113

Doi: 10.1016/j.devcel.2023.03.003

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Parasite Malate-Quinone Oxidoreductase Functionally Complements a Yeast Deletion Mutant of Mitochondrial Malate Dehydrogenase

Authors: Takeshi Ito, Sayaka Kajita, Minori Fujii, Yasuo Shinohara

Journal: Microbiol Spectr

PubMed ID: 37036365

Doi: 10.1128/spectrum.00168-23

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Synonymous alterations of cancer-associated Trp53 CpG mutational hotspots cause fatal developmental jaw malocclusions but no tumors in knock-in mice

Authors: Richard J Epstein, Frank P Y Lin, Robert A Brink, James Blackburn

Journal: PLoS ONE

PubMed ID: 37053216

Doi: 10.1371/journal.pone.0284327

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A replicon RNA vaccine can induce durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned

Authors: Megan A O'Connor, David W Hawman, Kimberly Meade-White, Shanna Leventhal, Wenjun Song, Samantha Randall, Jacob Archer, Thomas B Lewis, Brieann Brown, Megan N Fredericks, Kaitlin R Sprouse, Hillary C Tunggal, Mara Maughan, Naoto Iwayama, Chul Ahrens, William Garrison, Solomon Wangari, Kathryn A Guerriero, Patrick Hanley, Jamie Lovaglio, Greg Saturday, David Veesler, Paul T Edlefsen, Amit P Khandhar, Heinz Feldmann, Deborah Heydenburg Fuller, Jesse H Erasmus

Journal: PLoS Pathog

PubMed ID: 37075079

Doi: 10.1371/journal.ppat.1011298

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Immune responses to citrullinated and homocitrullinated peptides in healthy donors are not restricted to the HLA SE shared allele and can be selected into the memory pool

Authors: Ruhul H Choudhury, Ian Daniels, Poonam Vaghela, Suha Atabani, Thomas Kirk, Peter Symonds, Katherine W Cook, Abdullah Al-Omari, Daisy Weston, Sabaria Shah, David Hutchinson, Samantha J Paston, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant

Journal: Immunology

PubMed ID: 37055914

Doi: 10.1111/imm.13645

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A frame-shift mutation in COMTD1 is associated with impaired pheomelanin pigmentation in chicken

Authors: Huijuan Bi, Jonas Tranell, Dawn C Harper, Weifeng Lin, Jingyi Li, Anders R Hellström, Mårten Larsson, Carl-Johan Rubin, Chao Wang, Shumaila Sayyab, Susanne Kerje, Bertrand Bed'hom, David Gourichon, Shosuke Ito, Kazumasa Wakamatsu, Michèle Tixier-Boichard, Michael S Marks, Daniel Globisch, Leif Andersson

Journal: PLoS Genet

PubMed ID: 37068079

Doi: 10.1371/journal.pgen.1010724

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Structural and Biochemical Characterization of Zinc SufU-SufS Complex

Authors: Ingie Elchennawi, Philippe Carpentier, Christelle Caux, Marine Ponge, Sandrine Ollagnier de Choudens

Journal: Biomolecules

PubMed ID: 37238602

Doi: 10.3390/biom13050732

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19n01, a broadly neutralizing antibody against omicron BA1, BA2, BA4/5, and other SARS-CoV-2 variants of concern

Authors: Melissa García-Vega, Edgar A Melgoza-González, Sofía Hernández-Valenzuela, Diana Hinojosa-Trujillo, Mónica Reséndiz-Sandoval, Mara Anais Llamas-Covarrubias, Martín Loza-López, Olivia Valenzuela, Alan Soto-Gaxiola, Miguel A Hernández-Oñate, Verónica Mata-Haro, Irene Cassaniti, Josè Camilla Sammartino, Alessandro Ferrari, Luca Simonelli, Mattia Pedotti, Rui Sun, Fanglei Zuo, Fausto Baldanti, Luca Varani, Harold Marcotte, Qiang Pan-Hammarström, Jesús Hernández

Journal: iScience

PubMed ID: 37063467

Doi: 10.1016/j.isci.2023.106562

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Development of high cell density Limosilactobacillus reuteri KUB-AC5 for cell factory using oxidative stress reduction approach

Authors: Nisit Watthanasakphuban, Pimsiriya Srila, Phitsanu Pinmanee, Kamonwan Sompinit, Kittipong Rattanaporn, Clemens Peterbauer

Journal: Microb Cell Fact

PubMed ID: 37120528

Doi: 10.1186/s12934-023-02076-4

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mA epitranscriptomic regulation of tissue homeostasis during primate aging

Authors: Zeming Wu, Mingming Lu, Di Liu, Yue Shi, Jie Ren, Si Wang, Ying Jing, Sheng Zhang, Qian Zhao, Hongyu Li, Zihui Yu, Zunpeng Liu, Shijia Bi, Tuo Wei, Yun-Gui Yang, Jingfa Xiao, Juan Carlos Izpisua Belmonte, Jing Qu, Weiqi Zhang, Weimin Ci, Guang-Hui Liu

Journal: Nat Aging

PubMed ID: 37118553

Doi: 10.1038/s43587-023-00393-2

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An Orf-Virus (ORFV)-Based Vector Expressing a Consensus H1 Hemagglutinin Provides Protection against Diverse Swine Influenza Viruses

Authors: Gabriela Mansano do Nascimento, Dina Bugybayeva, Veerupaxagouda Patil, Jennifer Schrock, Ganesh Yadagiri, Gourapura J Renukaradhya, Diego G Diel

Journal: Viruses

PubMed ID: 37112974

Doi: 10.3390/v15040994

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A Silicon-Based PDMS-PEG Copolymer Microfluidic Chip for Real-Time Polymerase Chain Reaction Diagnosis

Authors: Siyu Yang, Qingyue Xian, Yiteng Liu, Ziyi Zhang, Qi Song, Yibo Gao, Weijia Wen

Journal: J Funct Biomater

PubMed ID: 37103298

Doi: 10.3390/jfb14040208

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Cotton peroxisome-localized lysophospholipase counteracts the toxic effects of Verticillium dahliae NLP1 and confers wilt resistance

Authors: Guilin Wang, Xinyu Wang, Jian Song, Haitang Wang, Chaofeng Ruan, Wenshu Zhang, Zhan Guo, Weixi Li, Wangzhen Guo

Journal: The plant journal: for cell and molecular biology

PubMed ID: 37026387

Doi: 10.1111/tpj.16236

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Pipeline to identify neoantigens exposed by radiation

Authors: Claire Lhuillier, Samantha J Van Nest, Nils-Petter Rudqvist, Sandra Demaria

Journal: Methods Cell Biol

PubMed ID: 37890930

Doi: 10.1016/bs.mcb.2023.02.010

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Development of a selection assay for small guide RNAs that drive efficient site-directed RNA editing

Authors: Juan Felipe Diaz Quiroz, Namrata Ojha, Elnur E Shayhidin, Dasuni De Silva, Jesse Dabney, Amy Lancaster, James Coull, Stuart Milstein, Andrew W Fraley, Christopher R Brown, Joshua J C Rosenthal

Journal: Nucleic Acids Res

PubMed ID: 36840708

Doi: 10.1093/nar/gkad098

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Media component bovine serum albumin facilitates the formation of mycobacterial biofilms in response to reductive stress

Authors: Parminder Singh Mavi, Shweta Singh, Ashwani Kumar

Journal: BMC Microbiol

PubMed ID: 37081437

Doi: 10.1186/s12866-023-02853-6

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Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence

Authors: Kathryn M Hastie, Xiaoying Yu, Fernanda Ana-Sosa-Batiz, Dawid S Zyla, Stephanie S Harkins, Chitra Hariharan, Hal Wasserman, Michelle A Zandonatti, Robyn Miller, Erin Maule, Kenneth Kim, Kristen M Valentine, Sujan Shresta, Erica Ollmann Saphire

Journal: Cell Rep

PubMed ID: 37083327

Doi: 10.1016/j.celrep.2023.112421

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Biochemical characterization of RNase R 2'-O-methylation sensitivity

Authors: Xiaolan Lu, Xiangwen Gu, Yong Li, Yifan Wu, Qiang Wang, Wenkui Yu, Qihan Chen

Journal: Biochimie

PubMed ID: 37105299

Doi: 10.1016/j.biochi.2023.04.016

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A small epitope shared by p53 and an unrelated protein upregulated after adenovirus infection

Authors: Jessica J Miciak, Fred Bunz

Journal: biorxiv

PubMed ID: 37162859

Doi: 10.1101/2023.04.28.538733

Protein-plastic interactions: The driving forces behind the high affinity of a carbohydrate-binding module for polyethylene terephthalate

Authors: Andrew Philip Rennison, Peter Westh, Marie Sofie Møller

Journal: The Science of the total environment

PubMed ID: 36739021

Doi: 10.1016/j.scitotenv.2023.161948

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A CsoR family transcriptional regulator, TTHA1953, controls the sulfur oxidation pathway in Thermus thermophilus HB8

Authors: John K Barrows, Michael W Van Dyke

Journal: The journal of biological chemistry

PubMed ID: 37116710

Doi: 10.1016/j.jbc.2023.104759

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An unexpected hydratase synthesizes the green light-absorbing pigment fucoxanthin

Authors: Tianjun Cao, Yu Bai, Paul Buschbeck, Qiaozhu Tan, Michael B Cantrell, Yinjuan Chen, Yanyou Jiang, Run-Zhou Liu, Nana K Ries, Xiaohuo Shi, Yan Sun, Maxwell A Ware, Fenghua Yang, Huan Zhang, Jichang Han, Lihan Zhang, Jing Huang, Martin Lohr, Graham Peers, Xiaobo Li

Journal: The Plant cell

PubMed ID: 37100425

Doi: 10.1093/plcell/koad116

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Evaluation of the Diagnostic Performance of Two Automated SARS-CoV-2 Neutralization Immunoassays following Two Doses of mRNA, Adenoviral Vector, and Inactivated Whole-Virus Vaccinations in COVID-19 Naïve Subjects

Authors: Eszter Csoma, Ágnes Nagy Koroknai, Renáta Sütő, Erika Szakács Szilágyi, Marianna Pócsi, Attila Nagy, Klára Bíró, János Kappelmayer, Béla Nagy

Journal: Microorganisms

PubMed ID: 37317161

Doi: 10.3390/microorganisms11051187

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