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Structural and functional properties of uridine 5'-monophosphate synthase from Coffea arabica

Authors: Alexis Hinojosa-Cruz, Ángel G Díaz-Sánchez, Adelaida Díaz-Vilchis, Lilian González-Segura

Journal: Int J Biol Macromol

PubMed ID: 38184030

Doi: 10.1016/j.ijbiomac.2024.129226

Products & Services: Molecular Biology Reagents

Circ_0007422 Knockdown Inhibits Tumor Property and Immune Escape of Colorectal Cancer by Decreasing PDL1 Expression in a miR-1256-Dependent Manner

Authors: Dian Yin, Li Yang, Xiu Feng, Xiaolu Zhai, Mei Hua, Jing Liu, Ying Chen

Journal: Mol Biotechnol

PubMed ID: 38253900

Doi: 10.1007/s12033-023-01040-2

Products & Services: Mutant Libraries

Phylogenetic conservation of Trop-2 across species-rodent and primate genomics model anti-Trop-2 therapy for pre-clinical benchmarks

Authors: Emanuela Guerra, Marco Trerotola, Valeria Relli, Rossano Lattanzio, Khouloud Boujnah, Nicole Travali, Antonino Moschella, Paolo Todaro, Laura Pierdomenico, Roberta Di Pietro, Nicola Tinari, Saverio Alberti

Journal: Front Genet

PubMed ID: 38250577

Doi: 10.3389/fgene.2023.1297367

Products & Services: Gene Synthesis

PlzA is a cyclic-di-GMP dependent DNA and RNA binding protein

Authors: Nerina Jusufovic, Andrew C Krusenstjerna, Christina R Savage, Timothy C Saylor, Catherine A Brissette, Wolfram R Zückert, Paula J Schlax, Md A Motaleb, Brian Stevenson

Journal: biorxiv

PubMed ID: 36778503

Doi: 10.1101/2023.01.30.526351

Products & Services: Molecular Biology Reagents

TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation

Authors: Xue Hao, Bo Zhao, Martina Towers, Liping Liao, Edgar Luzete Monteiro, Xin Xu, Christina Freeman, Hongzhuang Peng, Hsin-Yao Tang, Aaron Havas, Andrew V Kossenkov, Shelley L Berger, Peter D Adams, David W Speicher, David Schultz, Ronen Marmorstein, Kenneth S Zaret, Rugang Zhang

Journal: Nat Aging

PubMed ID: 38267705

Doi: 10.1038/s43587-023-00564-1

Products & Services: Mutant Libraries

Neutrophil-mediated type IV collagen degradation is elevated in patients with mild endoscopic ulcerative colitis reflecting early mucosal destruction

Authors: Marta S Alexdottir, Martin Pehrsson, Viktor Domislovic, Line E Godskesen, Aleksander Krag, Jens Kjeldsen, Marko Brinar, Ana Barisic, Anne-Christine Bay-Jensen, Morten A Karsdal, Zeljko Krznaric, Joachim H Mortensen

Journal: Sci Rep

PubMed ID: 38238446

Doi: 10.1038/s41598-024-52208-y

Products & Services: Catalog Peptides

Material assembly from collective action of shape-changing polymers

Authors: Mustafa K Abdelrahman, Robert J Wagner, Manivannan Sivaperuman Kalairaj, Mason Zadan, Min Hee Kim, Lindy K Jang, Suitu Wang, Mahjabeen Javed, Asaf Dana, Kanwar Abhay Singh, Sarah E Hargett, Akhilesh K Gaharwar, Carmel Majidi, Franck J Vernerey, Taylor H Ware

Journal: Nat Mater

PubMed ID: 38177377

Doi: 10.1038/s41563-023-01761-4

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LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL

Authors: Nadine Weinelt, Kaja Nicole Wächtershäuser, Gulustan Celik, Birte Jeiler, Isabelle Gollin, Laura Zein, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Boerries, Francesco Pampaloni, Sjoerd J L van Wijk

Journal: Cell Death Dis

PubMed ID: 38245534

Doi: 10.1038/s41419-024-06447-6

Age-Dependent and Aβ-Induced Dynamic Changes in the Subcellular Localization of HMGB1 in Neurons and Microglia in the Brains of an Animal Model of Alzheimer's Disease

Authors: Song-I Seol, Dashdulam Davaanyam, Sang-A Oh, Eun-Hwa Lee, Pyung-Lim Han, Seung-Woo Kim, Ja-Kyeong Lee

Journal: Cells

PubMed ID: 38247880

Doi: 10.3390/cells13020189

Products & Services: PCR Cloning and Subcloning

Combined Immunoinformatics to Design and Evaluate a Multi-Epitope Vaccine Candidate against Infection

Authors: Song Liang, Shidan Zhang, Yinli Bao, Yumin Zhang, Xinyi Liu, Huochun Yao, Guangjin Liu

Journal: Vaccines (Basel)

PubMed ID: 38400121

Doi: 10.3390/vaccines12020137

Products & Services: Catalog Antibodies

Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar ()

Authors: Paolo Valentini, Srinivas Akula, Abigail Alvarado-Vazquez, Jenny Hallgren, Zhirong Fu, Brett Racicot, Ingo Braasch, Michael Thorpe, Lars Hellman

Journal: Int J Mol Sci

PubMed ID: 38338947

Doi: 10.3390/ijms25031669

Products & Services: Molecular Biology Reagents

Knock-in mutagenesis in Drosophila Rdl underscores the critical role of the conserved M3 glycine in mediating the actions of broflanilide and isocycloseram on GABA receptors

Authors: Yoshihisa Ozoe, Toshifumi Nakao, Shu Kondo, Yasuhide Yoshioka, Fumiyo Ozoe, Shinichi Banba

Journal: Pestic Biochem Physiol

PubMed ID: 38458683

Doi: 10.1016/j.pestbp.2024.105776

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Screening and Identification of Anti-Idiotypic Nanobody Capable of Broad-Spectrum Recognition of the Toxin Binding Region of Lepidopteran Cadherins and Mimicking Domain II of Cry2Aa Toxin

Authors: Cheng Shen, Jiafeng Jin, Ziyan Huang, Meng Meng, Manman Lin, Xiaodan Hu, Qing Zhu, Chongxin Xu, Wei Chen, Johnson Lin, Xiao Zhang, Yuan Liu, Xianjin Liu

Journal: J Agric Food Chem

PubMed ID: 38221880

Doi: 10.1021/acs.jafc.3c07295

Products & Services: Molecular Biology Reagents

USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication

Authors: Hannah L Mackay, Helen R Stone, Katherine Ellis, George E Ronson, Alexandra K Walker, Katarzyna Starowicz, Alexander J Garvin, Patrick van Eijk, Alina Vaitsiankova, Sobana Vijayendran, James F Beesley, Eva Petermann, Eric J Brown, Ruth M Densham, Simon H Reed, Felix Dobbs, Marco Saponaro, Joanna R Morris

Journal: biorxiv

PubMed ID: 38260523

Doi: 10.1101/2024.01.10.574674

Products & Services: Molecular Biology Reagents

Construction and characterization of a humanized rat model with its application in evaluating the uptake of different statins

Authors: Yuanjin Zhang, Junze Huang, Shengbo Huang, Jie Liu, Luyao Deng, Chenmeizi Liang, Yuanqing Guo, Bingyi Yao, Xin Wang

Journal: Acta Pharm Sin B

PubMed ID: 38572097

Doi: 10.1016/j.apsb.2023.12.019

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Synthesis and mechanistic study of ultrashort peptides that inhibits Alzheimer's Aβ-aggregation-induced neurotoxicity

Authors: Naina Sehra, Rajesh Parmar, Indresh K Maurya, Vinod Kumar, Kulbhushan Tikoo, Rahul Jain

Journal: Bioorg Chem

PubMed ID: 38309001

Doi: 10.1016/j.bioorg.2024.107159

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PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation

Authors: Christopher Chin Sang, Gaelen Moore, Maria Tereshchenko, Michael L Nosella, Hongshan Zhang, T Reid Alderson, Morgan Dasovich, Anthony Leung, Ilya J Finkelstein, Julie D Forman-Kay, Hyun O Lee

Journal: biorxiv

PubMed ID: 38328070

Doi: 10.1101/2024.01.20.575817

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A novel opsonic eCIRP inhibitor for lethal sepsis

Authors: Colleen P Nofi, Chuyi Tan, Gaifeng Ma, Molly Kobritz, Jose M Prince, Haichao Wang, Monowar Aziz, Ping Wang

Journal: J Leukoc Biol

PubMed ID: 37774691

Doi: 10.1093/jleuko/qiad119

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CFL1 restores the migratory capacity of bone marrow mesenchymal stem cells in primary Sjögren's syndrome by regulating CCR1 expression

Authors: Mengxi Huang, Panpan Zhou, Yang Hang, Dan Wu, Nan Zhao, Genhong Yao, Xiaojun Tang, Lingyun Sun

Journal: Int Immunopharmacol

PubMed ID: 38183912

Doi: 10.1016/j.intimp.2024.111485

Products & Services: Molecular Biology Reagents

Delivery of mRNA with Histidine-Lysine Peptides

Authors: Qixin Leng, Jiaxi He, Aishwarya Anand, A James Mixson

Journal: Methods Mol Biol

PubMed ID: 38907929

Doi: 10.1007/978-1-0716-3918-4_23

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Precise coordination between nutrient transporters ensures fertility in the malaria mosquito Anopheles gambiae

Authors: Iryna Stryapunina, Maurice A Itoe, Queenie Trinh, Charles Vidoudez, Esrah Du, Lydia Mendoza, Oleksandr Hulai, Jamie Kauffman, John Carew, W Robert Shaw, Flaminia Catteruccia

Journal: PLoS Genet

PubMed ID: 38285728

Doi: 10.1371/journal.pgen.1011145

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LINC00662 promotes melanoma progression by competitively binding miR-107 and activating the β-catenin signaling pathway

Authors: Mengmeng Luo, Rui Lei, Qingfang Zhao, Yichen Shen, Zhigang He, Jinghong Xu

Journal: Int J Med Sci

PubMed ID: 38169586

Doi: 10.7150/ijms.84072

Products & Services: Molecular Biology Reagents

Glucose 6-phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production

Authors: Sri Harsha Adusumilli, Anuthariq Alikkam Veetil, Chinmayee Choudhury, Banani Chattopadhyaya, Diptimayee Behera, Anand Kumar Bachhawat

Journal: FEBS Open Bio

PubMed ID: 38124687

Doi: 10.1002/2211-5463.13755

Products & Services: Molecular Biology Reagents

Jianpi Antai formula prevents miscarriage by repressing M1 polarization of decidual macrophages through ubiquitination of NLRP3 mediated by MARCH7

Authors: Ying Zhao, Chenyun Miao, Ruye Wang, Yun Chen, Ning Ren, Jing Ma, Tao Gao, Qin Zhang

Journal: J Ethnopharmacol

PubMed ID: 38246482

Doi: 10.1016/j.jep.2024.117796

Products & Services: Protein Electrophoresis and Western

A pathologically expanded, clonal lineage of IL-21 producing CD4+ T cells drives Inflammatory neuropathy

Authors: Maryamsadat Seyedsadr, Madison Bang, Ethan McCarthy, Shirley Zhang, Ho-Chung Chen, Mahnia Mohebbi, Willy Hugo, Jason K Whitmire, Melissa G Lechner, Maureen A Su

Journal: biorxiv

PubMed ID: 38260637

Doi: 10.1101/2024.01.07.574553

Products & Services: ORF cDNA Clones/MolecularCloud

Molecular mechanisms and evolutionary robustness of a color switch in proteorhodopsins

Authors: Jiafei Mao, Xinsheng Jin, Man Shi, David Heidenreich, Lynda J Brown, Richard C D Brown, Moreno Lelli, Xiao He, Clemens Glaubitz

Journal: Sci Adv

PubMed ID: 38266078

Doi: 10.1126/sciadv.adj0384

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Polysaccharides Produced by Plant Growth-Promoting Rhizobacteria Strain sp BK01 Enhance Salt Stress Tolerance to

Authors: Enni Chen, Changsheng Yang, Weiyi Tao, Shuang Li

Journal: Polymers (Basel)

PubMed ID: 38201810

Doi: 10.3390/polym16010145

Products & Services: DNA Sequencing

Enantioselective Toxicity and Potential Endocrine-Disruptive Effects of the Insecticides Flufiprole and Ethiprole on

Authors: Lianshan Li, Xuejun Zhao, Kunming Hu, Weiye Xu, Minghua Wang, Hongjie Wang

Journal: J Agric Food Chem

PubMed ID: 38190123

Doi: 10.1021/acs.jafc.3c07896

Products & Services: Gene Synthesis

An inoculation site-retained mRNA vaccine induces robust immune responses against SARS-CoV-2 variants

Authors: Lei Huang, Fanfan Zhao, Muye He, Yi Fang, Xiaoping Ma, Shuaiyao Lu, Entao Li, Hui Xiao, Hanfei Zhu, Xueli Wang, Siyuan Tang, Bo Yu, Jie Wang, Dong Zhao, Chao Wang, Hangwen Li, Yuwei Gao, Xiaozhong Peng, Haifa Shen

Journal: J Control Release

PubMed ID: 38184234

Doi: 10.1016/j.jconrel.2024.01.002

Products & Services: Recombinant Proteins

High-Yield Lasso Peptide Production in a Bacterial Host by Plasmid Copy Number Engineering

Authors: Hannah N Fernandez, Ashley M Kretsch, Sylvia Kunakom, Adjo E Kadjo, Douglas A Mitchell, Alessandra S Eustáquio

Journal: ACS Synth Biol

PubMed ID: 38194362

Doi: 10.1021/acssynbio.3c00597

Products & Services: Gene Synthesis

Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection

Authors: Guorong Sun, Kai Alexander Kropp, Marieluise Kirchner, Nina Plückebaum, Anton Selich, Manutea Serrero, Akshay Dhingra, Jorge Rubén Cabrera, Birgit Ritter, Rudolf Bauerfeind, Emanuel Wyler, Markus Landthaler, Axel Schambach, Beate Sodeik, Philipp Mertins, Abel Viejo-Borbolla

Journal: MBio

PubMed ID: 38275838

Doi: 10.1128/mbio.03308-23

Products & Services: Codon Optimization

NRF2 mutation enhances the immune escape of hepatocellular carcinoma by reducing STING activation

Authors: Cheng Li, Gang Liang, Ke Yan, Yongheng Wang

Journal: Biochem Biophys Res Commun

PubMed ID: 38271834

Doi: 10.1016/j.bbrc.2024.149536

Products & Services: Mutant Libraries

Quaternization drives spleen-to-lung tropism conversion for mRNA-loaded lipid-like nanoassemblies

Authors: Yixuan Huang , Jiacai Wu , Sanpeng Li , Zhen Liu , Zhenghua Li , Boping Zhou , Bin Li

Journal: Theranostics

PubMed ID: 38169552

Doi: 10.7150/thno.90071

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Structure basis for recognition of plant Rpn10 by phytoplasma SAP05 in ubiquitin-independent protein degradation

Authors: Liying Zhang, Yunxiang Du, Qian Qu, Qingyun Zheng

Journal: iScience

PubMed ID: 38322988

Doi: 10.1016/j.isci.2024.108892

Products & Services: Protein and Antibody Isolation

A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity

Authors: Solange Moréra, Armelle Vigouroux, Magali Aumont-Nicaise, Mohammed Ahmar, Thibault Meyer, Abbas El Sahili, Grégory Deicsics, Almudena González-Mula, Sizhe Li, Jeanne Doré, Serena Siragu, Pierre Legrand, Camille Penot, François Andrè, Denis Faure, Laurent Soulère, Yves Queneau, Ludovic Vial

Journal: Biochem J

PubMed ID: 38058289

Doi: 10.1042/BCJ20230273

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Secretory carrier-associated membrane protein 5 regulates cell-surface targeting of T-type calcium channels

Authors: Emilio R Mustafá, Konstantin Weiß, Norbert Weiss

Journal: Channels (Austin)

PubMed ID: 37389974

Doi: 10.1080/19336950.2023.2230776

Products & Services: Gene Synthesis

Authors: Yunxiang Zhao, Jiali Qin, Jingshuai Sun, Jian He, Yanmei Sun, Renqiang Yuan, Zhili Li

Journal: Theriogenology

PubMed ID: 38150851

Doi: 10.1016/j.theriogenology.2023.11.028

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Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family

Authors: Benoit Arragain, Martin Pelosse, Albert Thompson, Stephen Cusack

Journal: Nat Commun

PubMed ID: 38066000

Doi: 10.1038/s41467-023-44044-x

Products & Services: Insect Expression

Addressing the Binding Mechanism of the Meprin and TRAF-C Homology Domain of the Speckle-Type POZ Protein Using Protein Engineering

Authors: Awa Diop, Paola Pietrangeli, Valeria Pennacchietti, Livia Pagano, Angelo Toto, Mariana Di Felice, Sara Di Matteo, Lucia Marcocci, Francesca Malagrinò, Stefano Gianni

Journal: Int J Mol Sci

PubMed ID: 38139193

Doi: 10.3390/ijms242417364

Products & Services: Antibody Modification and Purification Services

Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma: a first-in-human study

Authors: Yunlin Zhang, Ruchi P Patel, Ki Hyun Kim, Hyungwoo Cho, Jae-Cheol Jo, Seong Hyun Jeong, Sung Yong Oh, Yoon Seok Choi, Sung Hyun Kim, Ji Hyun Lee, Mathew Angelos, Puneeth Guruprasad, Ivan Cohen, Ositadimma Ugwuanyi, Yong Gu Lee, Raymone Pajarillo, Jong Hyun Cho, Alberto Carturan, Luca Paruzzo, Guido Ghilardi, Michael Wang, Soohwan Kim, Sung-Min Kim, Hyun-Jong Lee, Ji-Ho Park, Leiguang Cui, Tae Bum Lee, In-Sik Hwang, Young-Ha Lee, Yong-Jun Lee, Patrizia Porazzi, Dongfang Liu, Yoon Lee, Jong-Hoon Kim, Jong-Seo Lee, Dok Hyun Yoon, Junho Chung, Marco Ruella

Journal: Mol Cancer

PubMed ID: 38066564

Doi: 10.1186/s12943-023-01886-9

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N6-methyladenosine methylation analysis of long noncoding RNAs and mRNAs in 5-FU-resistant colon cancer cells

Authors: Jie Lai, Zhiyong Zhou, Kan Hu, HongLong Yu, Xingyao Su, Xiaoqiang Niu, Huizi Li, Shengxun Mao

Journal: Epigenetics

PubMed ID: 38145548

Doi: 10.1080/15592294.2023.2298058

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Combinatorial design of ionizable lipid nanoparticles for muscle-selective mRNA delivery with minimized off-target effects

Authors: Jingan Chen, Yue Xu, Muye Zhou, Shufen Xu, Andrew James Varley, Alex Golubovic, Rick Xing Ze Lu, Kevin Chang Wang, Mina Yeganeh, Daniel Vosoughi, Bowen Li

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38060560

Doi: 10.1073/pnas.2309472120

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Plasma circRNA HIPK2 as a putative biomarker for the diagnosis and prediction of therapeutic effects in major depressive disorder

Authors: Xiaoyu Yu, Zhenyu Fan, Tingting Yang, Heng Li, Yachen Shi, Long Ye, Rongrong Huang

Journal: Clin Chim Acta

PubMed ID: 38065380

Doi: 10.1016/j.cca.2023.117694

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Structural analysis and functional evaluation of the disordered ß–hexosyltransferase region from Hamamotoa (Sporobolomyces) singularis

Authors: Suzanne F Dagher, Asmita Vaishnav, Christopher B Stanley, Flora Meilleur, Brian F P Edwards , José M Bruno-Bárcena

Journal: Front Bioeng Biotechnol

PubMed ID: 38162180

Doi: 10.3389/fbioe.2023.1291245

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Intranasal mask for protecting the respiratory tract against viral aerosols

Authors: Xiaoming Hu, Shuang Wang, Shaotong Fu, Meng Qin, Chengliang Lyu, Zhaowen Ding, Yan Wang, Yishu Wang, Dongshu Wang, Li Zhu, Tao Jiang, Jing Sun, Hui Ding, Jie Wu, Lingqian Chang, Yimin Cui, Xiaocong Pang, Youchun Wang, Weijin Huang, Peidong Yang, Limin Wang, Guanghui Ma, Wei Wei

Journal: Nat Commun

PubMed ID: 38110357

Doi: 10.1038/s41467-023-44134-w

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Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs

Authors: Krystal C Johnson, Audrius Kilikevicius, Cristina Hofman, Jiaxin Hu, Yang Liu, Selina Aguilar, Jon Graswich, Yi Han, Tao Wang, Jill M Westcott, Rolf A Brekken, Lan Peng, Georgios Karagkounis, David R Corey

Journal: Nucleic Acids Res

PubMed ID: 38109320

Doi: 10.1093/nar/gkad1155

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Electrostatic-Dominated Conformational Fluctuations and Transition States of Phase Separation in Charge-Balanced Protein Polymer

Authors: Sougat Das, Tithi Basu, Saptarshi Majumdar

Journal: ACS Macro Lett

PubMed ID: 38109356

Doi: 10.1021/acsmacrolett.3c00625

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Sensitive Blood-Based Detection of HIV-1 and Mycobacterium tuberculosis Peptides for Disease Diagnosis by Immuno-Affinity Liquid Chromatography-Tandem Mass Spectrometry: A Method Development and Proof-of-Concept Study

Authors: Lin Li, Christopher J Lyon, Sylvia M LaCourse, Wenshu Zheng, Joshua Stern, Jaclyn N Escudero, Wilfred Bundi Murithi, Lilian Njagi, Grace John-Stewart, Thomas R Hawn, Videlis Nduba, Wael Abdelgaliel, Thomas Tombler, David Horne, Li Jiang, Tony Y Hu

Journal: Clin Chem

PubMed ID: 37956323

Doi: 10.1093/clinchem/hvad173

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Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate

Authors: Liyang Du , Qinwei Zhu & Zhonghui Lin

Journal: The EMBO Journal

Doi: 10.1038/s44318-023-00017-w

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Structural dynamics of the CROPs domain control stability and toxicity of Paeniclostridium sordellii lethal toxin

Authors: Yao Zhou, Xiechao Zhan , Jianhua Luo, Diyin Li , Ruoyu Zhou , Jiahao Zhang , Zhenrui Pan , Yuanyuan Zhang , Tianhui Jia , Xiaofeng Zhang , Yanyan Li , Liang Tao

Journal: Nat Commun .

PubMed ID: 38114525

Doi: 10.1038/s41467-023-44169-z

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Oat Peptides Alleviate Dextran Sulfate Sodium Salt-Induced Colitis by Maintaining the Intestinal Barrier and Modulating the Keap1-Nrf2 Axis

Authors: Zhong-Hao Ji, Wen-Yin Xie , Pei-Sen Zhao , Hong-Yu Wu , Wen-Zhi Ren , Jin-Ping Hu , Wei Gao , Bao Yuan

Journal: Nutrients .

PubMed ID: 38140314

Doi: 10.3390/nu15245055

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Staphylococcus aureus functional amyloids catalyze degradation of β-lactam antibiotics

Authors: Elad Arad , Kasper B Pedersen , Orit Malka, Sisira Mambram Kunnath , Nimrod Golan , Polina Aibinder , Birgit Schiøtt , Hanna Rapaport, Meytal Landau , Raz Jelinek

Journal: Nat Commun .

PubMed ID: 38081813

Doi: s41467-023-43624-1

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Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function

Authors: Leonardo A Parra-Rivas , Kayalvizhi Madhivanan , Brent D Aulston , Lina Wang , Dube Dheeraj Prakashchand , Nicholas P Boyer , Veronica M Saia-Cereda , Kristen Branes-Guerrero , Donald P Pizzo , Pritha Bagchi , V S Sundar , Yong Tang , Utpal Das , David A Scott , Padmini Rangamani , Yuki Ogawa , Subhojit Roy

Journal: Neuron .

PubMed ID: 38128479

Doi: 10.1016/j.neuron.2023.11.020

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Engineering minimal tissue inhibitors of metalloproteinase targeting MMPs via gene shuffling and yeast surface display

Authors: Arman Hosseini, Sachin Kumar, Kyle Hedin, Maryam Raeeszadeh-Sarmazdeh

Journal: Protein Sci

PubMed ID: 37807423

Doi: 10.1002/pro.4795

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Novel SOX10 indel mutations drive schwannomas through impaired transactivation of myelination gene programs

Authors: Erik A Williams, Ajay Ravindranathan, Rohit Gupta, Nicholas O Stevers, Abigail K Suwala, Chibo Hong, Somang Kim, Jimmy Bo Yuan, Jasper Wu, Jairo Barreto, Calixto-Hope G Lucas, Emily Chan, Melike Pekmezci, Philip E LeBoit, Thaddeus Mully, Arie Perry, Andrew Bollen, Jessica Van Ziffle, W Patrick Devine, Alyssa T Reddy, Nalin Gupta, Kristen M Basnet, Robert J B Macaulay, Patrick Malafronte, Han Lee, William H Yong, Kevin Jon Williams, Tareq A Juratli, Douglas A Mata, Richard S P Huang, Matthew C Hiemenz, Dean C Pavlick, Garrett M Frampton, Tyler Janovitz, Jeffrey S Ross, Susan M Chang, Mitchel S Berger, Line Jacques, Jun S Song, Joseph F Costello, David A Solomon

Journal: Neuro Oncol

PubMed ID: 37436963

Doi: 10.1093/neuonc/noad121

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Phage Tail Fiber Protein as a Specific Probe for Recognition of Shiga Toxin-Producing O91, O103, and O111

Authors: Yibao Chen, Lulu Li, Xiaotian Wei, Ming Hu, Xiaonan Zhao, Qing Zhang, Yanbo Luo, Min Zhao, Zhengjie Liu, Yumei Cai, Yuqing Liu

Journal: Anal Chem

PubMed ID: 38053255

Doi: 10.1021/acs.analchem.3c03370

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A functional and structural comparative analysis of Large Tumor Antigens reveals evolution of different importin α-dependent nuclear localization signals

Authors: Emily M Cross, Nasim Akbari, Hanieh Ghassabian, Mikayla Hoad, Silvia Pavan, Daryl Ariawan, Camilla M Donnelly, Enrico Lavezzo, Gayle F Petersen, Jade K Forwood, Gualtiero Alvisi

Journal: Protein Sci

PubMed ID: 38108201

Doi: 10.1002/pro.4876

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Choosing the right mouse model: comparison of humanized NSG and NBSGW mice for in vivo HSC gene therapy

Authors: Seunga Choo, Carl B Wolf, Heather M Mack, Mitchell J Egan, Hans-Peter Kiem, Stefan Radtke

Journal: Blood Adv

PubMed ID: 38113461

Doi: 10.1182/bloodadvances.2023011371

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The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways

Authors: Rayene Berkane, Hung Ho-Xuan, Marius Glogger, Pablo Sanz-Martinez, Lorène Brunello, Tristan Glaesner, Santosh Kumar Kuncha, Katharina Holzhüter, Sara Cano-Franco, Viviana Buonomo, Paloma Cabrerizo-Poveda, Ashwin Balakrishnan, Georg Tascher, Koraljka Husnjak, Thomas Juretschke, Mohit Misra, Alexis González, Volker Dötsch, Paolo Grumati, Mike Heilemann, Alexandra Stolz

Journal: Nat Commun

PubMed ID: 38102139

Doi: 10.1038/s41467-023-44101-5

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Ubiquitin-specific protease 22 promotes tumorigenesis and progression by an FKBP12/mTORC1/autophagy positive feedback loop in hepatocellular carcinoma

Authors: Qianwei Ye, Wei Zhou, Shengjun Xu, Qingyang Que, Qifan Zhan, Lincheng Zhang, Shusen Zheng, Sunbin Ling, Xiao Xu

Journal: MedComm (2020)

PubMed ID: 38045832

Doi: 10.1002/mco2.439

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Molecular Characterization of Tick-borne Pathogens in Bactrian Camels and Ticks from Gansu Province, China

Authors: Hong-Xi Zhao, Xiao-Qing Zan, Jin-Zhong Tao, Xin-Gang Dan

Journal: Acta Parasitol

PubMed ID: 38087038

Doi: 10.1007/s11686-023-00752-4

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Recombinant bovine FGF1 promotes muscle satellite cells mitochondrial fission and proliferation in serum-free conditions

Authors: Qingying Liu, Lianghua Xie, Wei Chen

Journal: Food Res Int

PubMed ID: 38129067

Doi: 10.1016/j.foodres.2023.113794

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Development of a double-antibody sandwich enzyme-linked immunosorbent assay for rapid detection of VZV

Authors: Aiping Wang, Na Liu, Jianguo Zhao, Yan Niu, Yumei Chen, Jingming Zhou, Enping Liu, Gaiping Zhang

Journal: J Virol Methods

PubMed ID: 38154579

Doi: 10.1016/j.jviromet.2023.114874

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Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents

Authors: Jaime S Rosa Duque, Samuel M S Cheng, Carolyn A Cohen, Daniel Leung, Xiwei Wang, Xiaofeng Mu, Yuet Chung, Tsun Ming Lau, Manni Wang, Wenyue Zhang, Yanmei Zhang, Howard H W Wong, Leo C H Tsang, Sara Chaothai, Tsz Chun Kwan, John K C Li, Karl C K Chan, Leo L H Luk, Jenson C H Ho, Wing Yan Li, Amos M T Lee, Jennifer H Y Lam, Sau Man Chan, Wilfred H S Wong, Issan Y S Tam, Masashi Mori, Sophie A Valkenburg, Malik Peiris, Wenwei Tu, Yu Lung Lau

Journal: World J Pediatr

PubMed ID: 38085470

Doi: 10.1007/s12519-023-00764-0

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Intracellular cholesterol visualization in brain tissue using D4H

Authors: Sherida M de Leeuw, Tal Nuriel

Journal: STAR Protoc

PubMed ID: 38100357

Doi: 10.1016/j.xpro.2023.102779

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A novel biomarker of MMP-cleaved cartilage intermediate layer protein-1 is elevated in patients with rheumatoid arthritis, ankylosing spondylitis and osteoarthritis

Authors: Helena Port, Cecilie Møller Hausgaard, Yi He, Walter P Maksymowych, Stephanie Wichuk, Dovile Sinkeviciute, Anne-Christine Bay-Jensen, Signe Holm Nielsen

Journal: Sci Rep

PubMed ID: 38066013

Doi: 10.1038/s41598-023-48787-x

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The role of CE16 exo-deacetylases in hemicellulolytic enzyme mixtures revealed by the biochemical and structural study of the novel TtCE16B esterase

Authors: Christina Pentari, Anastasia Zerva, Christos Kosinas, Panagiota Karampa, Vladimír Puchart, Maria Dimarogona, Evangelos Topakas

Journal: Carbohydr Polym

PubMed ID: 38171682

Doi: 10.1016/j.carbpol.2023.121667

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A biosynthetic network for protoberberine production in

Authors: Linrui Wu, Binxin Zhao, Zixin Deng, Bin Wang, Yi Yu

Journal: Hortic Res

PubMed ID: 38282690

Doi: 10.1093/hr/uhad259

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DPY30 promotes colorectal carcinoma metastasis by upregulating ZEB1 transcriptional expression

Authors: Chun-Ying Luo, Wei-Chao Su, Hai-Feng Jiang, Ling-Tao Luo, Dong-Yan Shen, Guo-Qiang Su

Journal: Cancer Cell Int

PubMed ID: 38115111

Doi: 10.1186/s12935-023-03126-y

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Rapid detection of in sputum using CRISPR-Cas12b combined with cross-priming amplification in a single reaction

Authors: Lijun Peng, Tingting Fang, Qingshan Cai, Hao Li, Huanyu Li, Haiqiong Sun, Mingzhi Zhu, Lingshan Dai, Yanqin Shao, Long Cai

Journal: J Clin Microbiol

PubMed ID: 38112450

Doi: 10.1128/jcm.00923-23

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Dachsous and Fat coordinately repress the Dachs–Dlish–Approximated complex to control growth

Authors: Hitoshi Matakatsu , Richard G Fehon

Journal: J Cell Biol

PubMed ID: 39373700

Doi: 10.1083/jcb.202406119

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Efficacy of cyclobutrifluram in controlling Fusarium crown rot of wheat and resistance risk of three Fusarium species to cyclobutrifluram

Authors: Haiyan Sun, Shiyan Cai, Yuanyu Deng, Shulin Cao, Xiaoyue Yang, Yanteng Lu, Wei Li, Huaigu Chen

Journal: Pestic Biochem Physiol

PubMed ID: 38225078

Doi: 10.1016/j.pestbp.2023.105723

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Purification of Human Cytoplasmic Actins From

Authors: Brian K Haarer, David C Amberg, Jessica L Henty-Ridilla

Journal: Bio Protoc

PubMed ID: 38094253

Doi: 10.21769/BioProtoc.4894

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Development of a therapeutic monoclonal antibody against circulating adipocyte fatty acid binding protein to treat ischaemic stroke

Authors: Boya Liao, Shilun Yang, Leiluo Geng, Jiuyu Zong, Zixuan Zhang, Mengxue Jiang, Xue Jiang, Simeng Li, Aimin Xu, Junlei Chang, Ruby Lai Chong Hoo

Journal: Br J Pharmacol

PubMed ID: 37949671

Doi: 10.1111/bph.16282

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Targeted HBx gene editing by CRISPR/Cas9 system effectively reduces epithelial to mesenchymal transition and HBV replication in hepatoma cells

Authors: Preety Rawal, Dinesh Mani Tripathi, Hamed Hemati, Jitendra Kumar, Purnima Tyagi, Shiv Kumar Sarin, Vikrant Nain, Savneet Kaur

Journal: Liver Int

PubMed ID: 38105495

Doi: 10.1111/liv.15805

Generation and Characterization of an Influenza D Reporter Virus

Authors: Lukas Probst, Laura Laloli, Manon Flore Licheri, Matthias Licheri, Mitra Gultom, Melle Holwerda, Philip V'kovski, Ronald Dijkman

Journal: Viruses

PubMed ID: 38140686

Doi: 10.3390/v15122444

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Cas9 degradation in human cells using phage anti-CRISPR proteins

Authors: Zuriah Meacham, Luisa Arake de Tacca, Joseph Bondy-Denomy, David Rabuka, Michael Schelle

Journal: PLoS Biol

PubMed ID: 38064533

Doi: 10.1371/journal.pbio.3002431

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Copper assisted sequence-specificchemical protein conjugation at a single backbone amide

Authors: Mengzhun Guo , Kai Zhao , Liang Guo , Rui Zhou , Qiuju He , Kuan Lu , Tian Li, Dandan Liu , Jinfeng Chen , Jing Tang , Xin Fu , Jinyun Zhou , Bei Zheng , Samuel I Mann , Yongdeng Zhang , Jing Huang , Bing Yang , Ting Zhou , Yingjie Lei , Bobo Dang

Journal: Nat Commun

PubMed ID: 38052794

Doi: 10.1038/s41467-023-43753-7

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Computational design of scFv anti-receptor binding domain of SARS-CoV-2 spike protein based on antibody S230 anti-SARS-CoV-1

Authors: Ade R R Firdaus, Umi Baroroh, Taufik Ramdani Tohari, Ari Hardianto, Toto Subroto, Muhammad Yusuf

Journal: J Biomol Struct Dyn

PubMed ID: 37880854

Doi: 10.1080/07391102.2023.2265485

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Dissecting components of the gene cluster under iron limitation

Authors: Tomas Richardson-Sanchez, Anson C K Chan, Brendil Sabatino, Helen Lin, Erin C Gaynor, Michael E P Murphy

Journal: Microbiol Spectr

PubMed ID: 38096459

Doi: 10.1128/spectrum.03148-23

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Combining protein and metabolic engineering strategies for high-level production of L-theanine in Corynebacterium glutamicum

Authors: Taowei Yang, Di Zhang, Mengmeng Cai, Hengwei Zhang, Xuewei Pan, Jiajia You, Xian Zhang, Meijuan Xu, Zhiming Rao

Journal: Bioresour Technol

PubMed ID: 38103752

Doi: 10.1016/j.biortech.2023.130200

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Enhancement of SARS-CoV-2 Infection via Crosslinking of Adjacent Spike Proteins by N-Terminal Domain-Targeting Antibodies

Authors: Tina Lusiany, Tohru Terada, Jun-Ichi Kishikawa, Mika Hirose, David Virya Chen, Fuminori Sugihara, Hendra Saputra Ismanto, Floris J van Eerden, Songling Li, Takayuki Kato, Hisashi Arase, Matsuura Yoshiharu, Masato Okada, Daron M Standley

Journal: Viruses

PubMed ID: 38140662

Doi: 10.3390/v15122421

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A lipid membrane-centric role of the SQSTM1/p62 body during autophagosome formation

Authors: Jinpei Zhang, Xintong He, Na Mi

Journal: Autophagy

PubMed ID: 38115546

Doi: 10.1080/15548627.2023.2297622

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DNA methylation editing in zebrafish

Authors: Fang Liang, Zijiong Dong, Jianmin Ye, Wei Hu, Ramji Kumar Bhandari, Kangsen Mai, Xuegeng Wang

Journal: Epigenetics

PubMed ID: 36945831

Doi: 10.1080/15592294.2023.2192326

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A semi-quantitative upconversion nanoparticle-based immunochromatographic assay for SARS-CoV-2 antigen detection

Authors: Hai Ding, Wanying Zhang, Shu-An Wang, Chuang Li, Wanting Li, Jing Liu, Fang Yu, Yanru Tao, Siyun Cheng, Hui Xie, Yuxin Chen

Journal: Front Microbiol

PubMed ID: 38149276

Doi: 10.3389/fmicb.2023.1289682

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RIF1 regulates early replication timing in murine B cells

Authors: Daniel Malzl, Mihaela Peycheva, Ali Rahjouei, Stefano Gnan, Kyle N Klein, Mariia Nazarova, Ursula E Schoeberl, David M Gilbert, Sara C B Buonomo, Michela Di Virgilio, Tobias Neumann, Rushad Pavri

Journal: Nat Commun

PubMed ID: 38081811

Doi: 10.1038/s41467-023-43778-y

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The V2 domain of HIV gp120 mimics an interaction between CD4 and integrin ⍺4β7

Authors: Donald Van Ryk, Sinmanus Vimonpatranon, Joe Hiatt, Sundar Ganesan, Nathalie Chen, Jordan McMurry, Saadiq Garba, Susie Min, Livia R Goes, Alexandre Girard, Jason Yolitz, Isabella Licavoli, Danlan Wei, Dawei Huang, Marcelo A Soares, Elena Martinelli, Claudia Cicala, James Arthos

Journal: PLoS Pathog

PubMed ID: 38064524

Doi: 10.1371/journal.ppat.1011860

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Antibody Response to SARS-CoV-2 Vaccination in Patients with End-Stage Kidney Disease on Hemodialysis

Authors: Rizky Andhika, Muhammad Iqbal Anand, Marita Restie Tiara, Josephine Debora, Hofiya Djauhari, Evan Susandi, Adnes Mareta, Asep Riswoko, Nopi Susilawati, Agnes Rengga Indrati, Bachti Alisjahbana, Rudi Supriyadi

Journal: Vaccines (Basel)

PubMed ID: 38140206

Doi: 10.3390/vaccines11121802

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Factors influencing COVID-19 mortality among cancer patients: A Brazilian multi-institutional study

Authors: Jessé Lopes da Silva, Bruno Santos Wance de Souza, Lucas Zanetti de Albuquerque, Sabina Bandeira Aleixo, Gilmara Anne da Silva Resende, Daniela Galvão Barros de Oliveira, Emerson Neves Dos Santos, Angélica Nogueira-Rodrigues, Renan Orsati Clara, Maria de Fatima Dias Gaui, Augusto Cesar de Andrade Mota, Vladmir Claudio Cordeiro de Lima, Daniela Dornelles Rosa, Rodrigo Ramella Munhoz, Igor Alexandre Protzner Morbeck, Ana Caroline Zimmer Gelatti, Clarissa Maria de Cerqueira Mathias, Andréia Cristina de Melo

Journal: PLoS ONE

PubMed ID: 38127882

Doi: 10.1371/journal.pone.0295597

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Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

Authors: Se Eun Kim, So Hee Park, Woo-Jung Park, Gayeong Kim, Seo Yeon Kim, Hyeran Won, Yun-Ho Hwang, Heeji Lim, Hyeon Guk Kim, You-Jin Kim, Dokeun Kim, Jung-Ah Lee

Journal: PLoS ONE

PubMed ID: 38060612

Doi: 10.1371/journal.pone.0295594

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, an AP2 and B3 Transcription Factor, Positively Regulates Eggplant's Response to Salt Stress

Authors: Junjie Ding, Bowen Yao, Xu Yang, Lei Shen

Journal: Plants (Basel)

PubMed ID: 38140500

Doi: 10.3390/plants12244174

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Revitalizing Skin Repair: Unveiling the Healing Power of Livisin, a Natural Peptide Calcium Mimetic

Authors: Xuehui Zhan, Danni Wang, Hanfei Wang, Hui Chen, Xinyi Wu, Tao Li, Junmei Qi, Tianbao Chen, Di Wu, Yitian Gao

Journal: Toxins

PubMed ID: 38251238

Doi: 10.3390/toxins16010021

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Anxiety and dysautonomia symptoms in patients with a Na17 mutation and the potential benefits of low-dose short-acting guanfacine

Authors: Rita de Cássia Collaço, Maxime Lammens, Carley Blevins, Kristen Rodgers, Andrei Gurau, Suguru Yamauchi, Christine Kim, Jeannine Forrester, Edward Liu, Jinny Ha, Yuping Mei, Corrine Boehm, Elizabeth Wohler, Nara Sobreira, Peter C Rowe, David Valle, Malcolm V Brock, Frank Bosmans

Journal: Clin Auton Res

PubMed ID: 38064009

Doi: 10.1007/s10286-023-01004-1

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High-resolution HLA genotyping in inclusion body myositis refines 81 ancestral haplotype association to DRB1*03:01:01 and highlights pathogenic role of arginine-74 of DRβ1 chain

Authors: Nataliya Slater, Anuradha Sooda, Emily McLeish, Kelly Beer, Anna Brusch, Rakesh Shakya, Christine Bundell, Ian James, Abha Chopra, Frank L Mastaglia, Merrilee Needham, Jerome D Coudert

Journal: J Autoimmun

PubMed ID: 38043487

Doi: 10.1016/j.jaut.2023.103150

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Shank3 ameliorates neuronal injury after cerebral ischemia/reperfusion via inhibiting oxidative stress and inflammation

Authors: Hongchen Zhang, Yuan Feng, Yanfang Si, Chuanhao Lu, Juan Wang, Shiquan Wang, Liang Li, Wenyu Xie, Zheming Yue, Jia Yong, Shuhui Dai, Lei Zhang, Xia Li

Journal: Redox Biol

PubMed ID: 38064762

Doi: 10.1016/j.redox.2023.102983

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Bivalent inhibitors of the BTB E3 ligase KEAP1 enable instant NRF2 activation to suppress acute inflammatory response

Authors: Mengchen Lu, Jianai Ji, Yifei Lv, Jing Zhao, Yuting Liu, Qiong Jiao, Tian Liu, Yi Mou, Qidong You, Zhengyu Jiang

Journal: Cell Chem Biol

PubMed ID: 38157852

Doi: 10.1016/j.chembiol.2023.12.005

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Development of a fluorescent multiplexed lateral flow immunoassay for the simultaneous detection of crustacean allergen tropomyosin, sarcoplasmic calcium binding protein and egg allergen ovalbumin in different matrices and commercial foods

Authors: Yuhao Huang, Ranran Li, Wenye Zhu, Jinlong Zhao, Hao Wang, Ziye Zhang, Hong Lin, Wenjie Li, Zhenxing Li