客户发表文献

至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 3/524 每页显示数量

A broadly neutralizing antibody confers cross-genus protection against alphaherpesviruses by inhibiting gB-mediated membrane fusion

Authors: Guosong Wang, Yu Li, Chongxin Wu, Tian Chen, Mengxuan Gui, Yue Zeng, Hui Sun, Kaiyun Chen, Xiangfeng Xi, Yanbo Yang, Yuchen Jiang, Yanan Jiang, Liqin Liu, Chengyu Yang, Jiarui Xin, Caihong Liu, Yiyi Li, Ningning Huo, Yang Huang, Lina Lin, Hai Yu, Chenghao Huang, Quan Yuan, Shaowei Li, Kegong Tian, Qingbing Zheng, Ningshao Xia, Yixin Chen

Journal: Nature Communications

PubMed ID: 41402251

Doi: 10.1038/s41467-025-66099-8

Products & Services: Antibody Modification and Purification Services

Gene-corrected regulatory T cell therapy for IL2RA deficiency

Authors: Alvin S Ha, Nechama Kalter, Michael Rosenberg, Luis A Acevedo, Brianna Liang, Weihong Liu, Sreenivasan Paruthiyil, Meenal Sinha, Alexander Vu, Vinh Nguyen, Zhongxia Qi, Netravathi Krishnappa, Jinna Shu, Jingwei Yu, Jason Catanzaro, Jeffrey A Bluestone, Qizhi Tang, Fyodor D Urnov, Alexander Marson, Ayal Hendel, Kevan C Herold, Brian R Shy, Jonathan H Esensten

Journal: Molecular Therapy

PubMed ID: 41376159

Doi: 10.1016/j.ymthe.2025.12.004

Products & Services: Molecular Biology Reagents

Structural insights into kainate receptor desensitization

Authors: Changping Zhou, Guadalupe Segura-Covarrubias, Nami Tajima

Journal: Nature Communications

PubMed ID: 41365859

Doi: 10.1038/s41467-025-65920-8

Human Substance P Interactions with G Protein-Coupled Receptor NK1R Observed by NMR in Solution

Authors: Haoyi Ge, Lingyun Yang, Changran Chen, Yuxin Xu, Dongsheng Liu, Kurt Wüthrich

Journal: Journal of the American Chemical Society

PubMed ID: 41264783

Doi: doi.org/10.1021/jacs.5c12553

Products & Services: Peptide Synthesis

Far-red light orchestrates antiviral defense in plants

Authors: Qian Gong, Linfang He, Fan Huang, Yunjing Wang, Jinchuan Xie, Yiguo Hong, Yule Liu

Journal: SCIENCE ADVANCES

PubMed ID: 41259508

Doi: 10.1126/sciadv.adz7663

Products & Services: Protein and Antibody Isolation

CSF3 enhances the innate immune responses to ALV-J infections via NF-κB and interferon pathways

Authors: Junliang Xia, Weiding Chen, Chengxun Xu, Meihuizi Wang, Guodong Mo, Xiquan Zhang

Journal: poultry science

PubMed ID: 40812136

Doi: 10.1016/j.psj.2025.105648

Products & Services: Plasmid DNA Preparation

A yeast surface display platform for characterizing CAR T cell responses to cancer antigens

Authors: Marcus Deichmann, Giovanni Schiesaro, Keerthana Ramanathan, Katrine Zeeberg, Nanna M T Koefoed, Maria Ormhøj, Rasmus U W Friis, Ryan T Gill, Sine R Hadrup, Emil D Jensen, Michael K Jensen

Journal: Nature Communications

PubMed ID: 41271729

Doi: 10.1038/s41467-025-65236-7.

Products & Services: Peptide Synthesis

Modeling and addressing on-target/off-tumor toxicity of claudin 18.2 targeted immunotherapies

Authors: Elizabeth J Carstens, Kazuki Takahashi, Naoya Sakamoto, Martina De Vizio, Micaela Morgado, Shahryar Khoshtinat Nikkhoi, Abhishek Mangipudi, Canh Hiep Nguyen, Tate Weltzin, Izuma Nakayama, Qiang Lv, Jue Zeng, Cui Nie, Changjing Deng, Xiaoxiao Wang, Lile Liu, Samuel J Klempner, Anusuya Ramasubramanian, Jonathan A Nowak, Andrew J Aguirre, Kohei Shitara, Eric L Smith

Journal: Nature Communications

PubMed ID: 41176582

Doi: 10.1038/s41467-025-65148-6.

Products & Services: Recombinant Proteins

Pmt4 recognizes two separate acceptor sites to O-mannosylate in the S/T-rich regions of substrate proteins

Authors: Minge Du, Zuanning Yuan, Amanda Kovach, Meinan Lyu, Huilin Li

Journal: Nature Communications

PubMed ID: 41188226

Doi: 10.1038/s41467-025-64729-9.

Products & Services: Protein and Antibody Isolation

StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models

Authors: Massimo Saini, Francesc Castro-Giner, Adriana Hotz, Magdalena K Sznurkowska, Manuel Nüesch, François M Cuenot, Selina Budinjas, Gilles Bilfeld, Ece Su Ildız, Karin Strittmatter, Ilona Krol, Zoi Diamantopoulou, Aino Paasinen-Sohns, Maria Waldmeier, Rafaela Cássio, Susanne Kreutzer, Zacharias Kontarakis, Ana Gvozdenovic, Nicola Aceto

Journal: Cell

PubMed ID: 41205600

Doi: 10.1016/j.cell.2025.10.007.

Products & Services: Gene Synthesis

Bidirectional communication between nucleotide and substrate binding sites in a type IV multidrug ABC transporter

Authors: Victor Hugo Pérez Carrillo, Margot Di Cesare, Dania Rose-Sperling, Waqas Javed, Hannes Neuweiler, Julien Marcoux, Cédric Orelle, Jean-Michel Jault, Ute A Hellmich

Journal: Nature Communications

PubMed ID: 41219214

Doi: 10.1038/s41467-025-65037-y.

A bispecific antibody targeting PD-L1/TNFR2 increases tumor targeting and enhances antitumor efficacy in colorectal cancer

Authors: Xiaozhen Kang, Peng Qian, Yifeng Han, Mengdi Wu, Yuxin Li, Chun Xu, Jiwu Wei

Journal: Journal for ImmunoTherapy of Cancer

PubMed ID: 41238220

Doi: https://doi.org/10.1136/jitc-2025-013001

Products & Services: Catalog Antibodies

Early CD4+ T-cell immune reconstitution as a biomarker for Epstein-Barr virus control following allogeneic transplantation

Authors: Kexin Lin, Wenwen Yang, Jiaxiu Yin, Jing Luo, Hao Zhou, Lanxiang Liu, Li Yang, Jie Luo, Lin Liu, Junli Mou

Journal: Blood research

PubMed ID: 41186900

Doi: 10.1007/s44313-025-00106-1

Products & Services: Molecular Biology Reagents

Double-stranded DNA deaminase DddAE1347A can increase the efficiency and targeting range of cytidine base editors

Authors: Yuqiang Qian, Fengjiao Hui, Wenchao Niu, Di Wang, Yang Hao, Qingying Meng, Siyu Ren, Deqiang Kong, Heng Gong, Jiayu Wu, Kexin Chen, Muna Alariqi, Junping Gao, Zhanjun Li, Shuangxia Jin

Journal: Genome Biology

PubMed ID: 41250247

Doi: 10.1186/s13059-025-03849-3

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Glutathionylated DNA adducts accumulate in mitochondrial DNA and are regulated by AP endonuclease 1 and tyrosyl-DNA phosphodiesterase 1

Authors: Yu Hsuan Chen, Martin Esparza Sanchez, Ta I Hung, Jin Tang, Wenyan Xu, Jiekai Yin, Yinsheng Wang, Chia-En A Chang, Huimin Zhang, Junjie Chen, Linlin Zhao

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41259143

Doi: doi.org/10.1073/pnas.2509312122

Products & Services: Catalog Antibodies

Engineering Multicellular Inter-communication Systems Using a Synthetic Homodimer-inducible Kinase Receptor

Authors: Quan Zhang, Miao Zhang, Yao Zhang, Fenglin Wang, Jian-Hui Jiang

Journal: Angewandte Chemie (International ed. in English)

PubMed ID: 41267507

Doi: 10.1002/anie.202513254

Products & Services: PCR Cloning and Subcloning DNA Sequencing

SLC7A11-independent disulfidptosis induced by a two-pronged delivery strategy for bladder cancer chemotherapy and cisplatin-resistance reverse

Authors: Bin Zheng, Facai Zhang, Heng Wang, Wenyan Zuo, Dingyi Liu, Zhihan Wu, Zhenghong Liu, Haichang Li, Yang Liu, Yixuan Mou, Xiaowen Qin, Dahong Zhang, Pu Zhang, Qi Zhang

Journal: Materials today. Bio

PubMed ID: 41322137

Doi: 10.1016/j.mtbio.2025.102547

Products & Services: Protein and Antibody Isolation

Unveiling conformation-selective regulation of the norepinephrine transporter

Authors: Heng Zhang, Tianwei Zhang, Dingyan Wang, Antao Dai, Jianhang Mao, Qihui Chen, Tianyuan Du, Xue Lu, Yongxin Hao, Chao Zhang, Yu-Ling Yin, Wen Hu, Benxun Pan, Sanshan Jin, Mengting Jiang, Yuan Si, Qingning Yuan, Ming-Wei Wang, Mingyue Zheng, Zhen Wang, Dehua Yang, H Eric Xu, Yi Jiang

Journal: Cell

PubMed ID: 41138730

Doi: 10.1016/j.cell.2025.10.002

Products & Services: Protein and Antibody Isolation

A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes

Authors: Enzo Mameli, George-Rafael Samantsidis, Raghuvir Viswanatha, Hyeogsun Kwon, David R Hall, Matthew Butnaru, Yanhui Hu, Stephanie E Mohr, Norbert Perrimon, Ryan C Smith

Journal: Nature Communications

PubMed ID: 41285753

Doi: 10.1038/s41467-025-65304-y.

Products & Services: PCR Cloning and Subcloning

PROTAC repurposing uncovers a noncanonical binding surface that mediates chemical degradation of nuclear receptors

Authors: Andrew D Huber, Wenwei Lin, Young-Hwan Jung, Shyaron Poudel, Guangwei Yang, Jing Wu, Annalise G Carrigan, Vishwajeeth Pagala, Wei Wang, Yingxue Fu, Zuo-Fei Yuan, Stephanie D Byrum, Ka Yang, Rebecca R Florke Gee, Elizabeth D Arnold, Allister J Loughran, Jingheng Wang, Shondra M Pruett-Miller, Junmin Peng, Taosheng Chen

Journal: Nature Communications

PubMed ID: 41198675

Doi: 10.1038/s41467-025-64773-5.

Products & Services: Bacterial Expression

A fungal pathogen manipulates phytocytokine signaling for plant infection

Authors: Chenlei Hua, Lisha Zhang, Annick Stintzi, Andreas Schaller, Hui-Shan Guo, Thorsten Nürnberger

Journal: Nature Communications

PubMed ID: 41238555

Doi: 10.1038/s41467-025-65934-2.

Products & Services: Peptide Synthesis

Spike conformational and glycan heterogeneity associated with furin cleavage causes incomplete neutralization of SARS-CoV-2

Authors: Sahil Kumar, Rathina Delipan, Chanchal Sharma, Jyoti Jadoun, Kawkab Kanjo, Randhir Singh, Raju Rajmani, Suprit Deshpande, Rajesh Pandey, Krishan G Thakur, Jayanta Bhattacharya, Rogier W Sanders, Marit J van Gils, Raghavan Varadarajan, Rajesh P Ringe

Journal: Nature Communications

PubMed ID: 41257850

Doi: 10.1038/s41467-025-65099-y.

Structure of the human astrovirus capsid spike in complex with the neonatal Fc receptor

Authors: Adam Lentz, Sarah Lanning, Khurshid R Iranpur, Lena Ricemeyer, Carlos F Arias, Rebecca M DuBois

Journal: Nature Communications

PubMed ID: 41184319

Doi: 10.1038/s41467-025-65203-2.

Products & Services: Mutagenesis Services

FUS nanoclusters are a distinct state within the dilute phase

Authors: Yingda Ge, Tapas Paul, Margarita Gordiychuk, Nilimesh Das, Yaojun Zhang, Sua Myong

Journal: Nature Communications

PubMed ID: 41224766

Doi: 10.1038/s41467-025-64909-7.

TNC-targeted CAR-macrophage therapy alleviates liver fibrosis in mice

Authors: Kai-Zhao Chen, Zi-Yang Lin, Long-Jun Chen, You-Xi Zhou, Wei Zhang, Hao-Yang Wan, Yong-Kun Huo, Qi Fu, Zi-Qing Gao, Hong-Wei Cheng, Xiao-Dong Ma, Shuai-Shuai Zhang

Journal: Military Medical Research

PubMed ID: 41214839

Doi: 10.1186/s40779-025-00667-3

Products & Services: Protein and Antibody Isolation

Double-stranded DNA deaminase DddAE1347A can increase the efficiency and targeting range of cytidine base editors

Authors: Yuqiang Qian, Fengjiao Hui, Wenchao Niu, Di Wang, Yang Hao, Qingying Meng, Siyu Ren, Deqiang Kong, Heng Gong, Jiayu Wu, Kexin Chen, Muna Alariqi, Junping Gao, Zhanjun Li, Shuangxia Jin

Journal: Genome Biology

PubMed ID: 41250247

Doi: doi.org/10.1186/s13059-025-03849-3

Products & Services: Gene Fragments

RBM39 Contributes to MGMT Maintenance in Response to Temozolomide-Induced DNA Damage

Authors: Vahid Khalaj, Jack T Adams, Solmaz AghaAmiri, Servando Hernandez Vargas, Tyler M Bateman, Sukhen C Ghosh, Majid Momeny, Ali Azhdarinia

Journal: Cancers

PubMed ID: 41300971

Doi: 10.3390/cancers17223604

Products & Services: Protein Electrophoresis and Western

Amplification-free cancer diagnosis based on inhibition of Cas12a activity by site-specific 5mC-modified cfDNA

Authors: Feng Yang, Can Xu, Chunhong Li, Xinni Xiang, Yi Zhao, Cong Hu, Huan Rong, Yu He, Jingyu Li, Yu Wang, Chao Tang, Xiaoyu Liu, Renyan Li, Fei Deng, Tingxiu Xiang

Journal: Nucleic Acids Research

PubMed ID: 41404798

Doi: doi.org/10.1093/nar/gkaf1383

Products & Services: Catalog Gene Editing

Nonexpansive biodegradable matrix promotes blood vessel organoid development for neurovascular repair and functional recovery in ischaemic stroke

Authors: Dongling Xiao, Yue Sun, Guanyuan Yang, Weixi Yan, Meilin Jiang, Zhongliang Qin, Zijun Wang, Yawei Gu, Jingting Zhou, Ju Tan, Gang Li, Yinghao Li, Chuhong Zhu

Journal: Nature biomedical engineering

PubMed ID: 41184604

Doi: 10.1038/s41551-025-01550-1

Products & Services: Peptide Library Services

Intravaginal delivery of mRNA-encoded antibodies with enhanced breadth and potency for SHIV/HIV protection

Authors: Jae Yeon Joo, Peng Xiao, Susan P John, Daryll Vanover, Hannah E Peck, Loren E Sasser, Deepanwita Bose, Younghun Jung, Jaehyeon Hwang, Chiara Zurla, Francois Villinger, Philip J Santangelo

Journal: Nature Communications

PubMed ID: 41290645

Doi: doi.org/10.1038/s41467-025-65456-x

Products & Services: Gene Synthesis Catalog Antibodies

Genome-Wide Identification of GW5-LIKE Family Revealed the Function of ClGL1 Involved in Fruit and Seed Shape by Mediating Brassinosteroid Signaling in Watermelon

Authors: Peng Tian, Lei Zhang, Jingjing Zhang, Bowen Liu, Wei Liu, Bing Li, Xiurui Gao, Jie Zhang, Yanrong Wu, Yong Xu

Journal: Horticulturae

Doi: 10.3390/horticulturae11111326

Products & Services: Custom DNA/RNA Oligos

Wild-type KRAS activation drives evasion of interferon-mediated immunity and resistance to immunotherapy in hepatocellular carcinoma

Authors: Martina Mang Leng Lei, Carmen Oi Ning Leung, Rainbow Wing Hei Leung, Xue Qian Wu, Katherine Po Sin Chung, Catherine Yu Jia Gu, Mandy Sze Man Chan, Wing Ki Chau, Quan Hua Mu, Kai Yu Ng, Man Tong, Jing Ping Yun, Jia Ming Nickolas Teo, Guang Sheng Ling, Patrick Pak Chun Wong, Stephen Lam Chan, Zhe Wen Xiong, Alfred Sze Lok Cheng, Jin Ding, Stephanie Ma, Terence Kin Wah Lee

Journal: Nature Communications

PubMed ID: 41219194

Doi: 10.1038/s41467-025-64860-7.

Products & Services: Mutagenesis Services

High expression of interleukin-18 receptor alpha correlates with severe respiratory viral disease and defines T cells with reduced cytotoxic signatures

Authors: Aira F Cabug, Jeremy Chase Crawford, Hayley A McQuilten, Isabelle J H Foo, Lilith F Allen, Deborah Gebregzabher, Robert C Mettelman, Tanya Novak, Janet Chou, Louise C Rowntree, Ruth R Hagen, Abby J Thomson, Genevieve E Martin, Brad Gilbertson, Michael Nt Souter, Fiona James, Emma Goodall, Simone Rizzetto, Tim Flerlage, Xiaoxiao Jia, Lee-Ann Van de Velde, So Young Chang, Fabio Luciani, Ryan S Thwaites, Jason A Trubiano, Tom C Kotsimbos, Allen C Cheng, Adrienne G Randolph, Paul G Thomas, Jianqing Xu, Zhongfang Wang, Thi H O Nguyen, Brendon Y Chua, Lukasz Kedzierski, Katherine Kedzierska

Journal: Nature Communications

PubMed ID: 41285788

Doi: 10.1038/s41467-025-65262-5.

Products & Services: Peptide Synthesis

Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma

Authors: Edward Z Song, Andrea Timpanaro, Michael Meechan, Leonel Elena-Sanchez, Lucy Z Li, Sophie Jamet, Davina S Lau, Lily I Winter, Matthew D Dun, Jessica B Foster, Myron K Evans, Siobhan S Pattwell, Vandana Kalia, Surojit Sarkar, Michael C Jensen, Matthew C Biery, Nicholas A Vitanza

Journal: Nature Communications

PubMed ID: 41219209

Doi: 10.1038/s41467-025-64861-6.

Products & Services: Protein and Antibody Isolation

Control of Mycobacterium tuberculosis protein secretion by ESX-4 and the outer membrane EsxUT-EsxEF complex

Authors: Rashmi Ravindran Nair, Virginia Meikle, Swati Dubey, Mikhail Pavlenok, Anna D Tischler, Michael Niederweis

Journal: Nature Communications

PubMed ID: 41266320

Doi: 10.1038/s41467-025-65061-y.

Products & Services: Polyclonal Antibody Services

Glycerol-3-phosphate activates ChREBP, FGF21 transcription and lipogenesis in citrin deficiency

Authors: Vinod Tiwari, Byungchang Jin, Olivia Sun, Edwin D J Lopez Gonzalez, Min-Hsuan Chen, Xiwei Wu, Hardik Shah, Andrew Zhang, Mark A Herman, Cassandra N Spracklen, Russell P Goodman, Charles Brenner

Journal: Nature metabolism

PubMed ID: 41238906

Doi: 10.1038/s42255-025-01399-3.

Interpretable molecular decision-making with DNA-based scalable and memory-efficient tree computation

Authors: Junlan Liu, Qian Tang, Yongqi Han, Jinxing Song, Fei Wang, Pei Guo, Chunhai Fan, Weihong Tan, Da Han

Journal: Nature Communications

PubMed ID: 41271734

Doi: 10.1038/s41467-025-66610-1.

Comparative analysis of adenovirus, mRNA, and protein vaccines reveals context-dependent immunogenicity and efficacy

Authors: Bakare Awakoaiye, Shiyi Li, Sarah Sanchez, Tanushree Dangi, Nahid Irani, Laura Arroyo, Gabriel Arellano, Shadi Mohammadabadi, Malika Aid, Pablo Penaloza-MacMaster

Journal: JCI Insight

PubMed ID: 41212056

Doi: 10.1172/jci.insight.198069

Products & Services: Custom mRNA synthesis

Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins

Authors: Wenjian Han, Bo Yuan, Xiaojuan Fan, Weike Li, Yiting Yuan, Yuefang Zhang, Shu Wang, Shifang Shan, Markus Hafner, Zefeng Wang, Zilong Qiu

Journal: Nature Communications

PubMed ID: 41188225

Doi: 10.1038/s41467-025-64748-6.

Products & Services: Gene Synthesis

Structural snapshots capture nucleotide release at the μ-opioid receptor

Authors: Saif Khan, Aaliyah S Tyson, Mohsen Ranjbar, Zixin Zhang, Jaskaran Singh, Gye Won Han, Cornelius Gati

Journal: Nature

PubMed ID: 41193810

Doi: 10.1038/s41586-025-09677-6.

Products & Services: Catalog Peptides

Potential of ferulic acid as a food-derived cardioprotective agent targeting mitochondrial dysfunction

Authors: Duanrui Cao, Lina Huang, Xiaowei Lu, Junhua Meng, Wenhong Li, Delin Duan, Qianqian Wang, Cuiping Liu, Zidong Qiu, Ni Zhang

Journal: Food Bioscience

Doi: //doi.org/10.1016/j.fbio.2025.107704

Products & Services: Custom DNA/RNA Oligos

Enhanced antigen presentation by macrophages promotes human atherosclerosis progression: therapeutic implications

Authors: Yuhuai Xie, Que Wu, Yunhui Jia, Lianping Cheng, Yaru Tian, Xian Yang, Wei Wang, Wei Xu, Zhen Zhao, Yuanyuan Wei

Journal: European heart journal

PubMed ID: 41217874

Doi: 10.1093/eurheartj/ehaf878

Products & Services: Synthetic Guide RNA

Structural and functional characterization of TgGSK3, a druggable kinase in Toxoplasma gondii

Authors: Silvia Diaz-Martin, Christopher Swale, Valeria Bellini, Irina Dobrescu, Janine Wenker, Marie-Pierre Brenier-Pinchart, Laurence Braun, Alwéna Tollec, Charlotte Corrao, Yohann Couté, Caroline Mas, Fabrice Laurent, Matthew Bowler, Mohamed-Ali Hakimi, Alexandre Bougdour

Journal: Nature Communications

PubMed ID: 41193440

Doi: 10.1038/s41467-025-64701-7.

Products & Services: Gene Synthesis

Plexin-B1 safeguards astrocyte agility and glial alignment to facilitate wound corralling and axon pathfinding in mouse spinal cord injury model

Authors: Haofei Ni, Zhilai Zhou, Molly Estill, Dalia Halawani, Chrystian Junqueira Alves, Li Shen, Ning Xie, Roland H Friedel, Hongyan Zou

Journal: Nature Communications

PubMed ID: 41253783

Doi: 10.1038/s41467-025-65095-2.

Products & Services: Protein Electrophoresis and Western

A plastid carbohydrate carrier mediates ribose recycling from nucleotide catabolism and glucose export from starch degradation

Authors: Luisa Voß, Isabel Keller, Rebekka Schröder, Denise Mehner-Breitfeld, André Specht, Gerald Dräger, Jannis Rinne, Jakob Franke, Nieves Medina-Escobar, Marco Herde, Thomas Brüser, H Ekkehard Neuhaus, Claus-Peter Witte

Journal: Nature Communications

PubMed ID: 41193506

Doi: 10.1038/s41467-025-65510-8

Products & Services: Monoclonal Antibody Services

ARMH2 is a cytosolic component of CatSper crucial for sperm function

Authors: Qingqing Zhao, Shiyi Lin, Hang Kang, Yanfei Ru, Qikui Xu, Zijing Yu, Xiaofang Huang, Carlo De Rito, Giulia Sassi, Shaojie Wang, Shuya Sun, Rui Sun, Honghan Cheng, Yi Zhu, Mingxi Liu, Yongdeng Zhang, Min Jiang, Riccardo Percudani, Jean-Ju Chung, Xuhui Zeng, Zhen Yan, Jianping Wu

Journal: Nature Communications

PubMed ID: 41271765

Doi: 10.1038/s41467-025-65952-0.

Products & Services: Protein and Antibody Isolation

A chromosome-level genome of Astilbe chinensis unveils the evolution of a terpene biosynthetic gene cluster

Authors: Fangfang Chen, Yan Yao, Hangzhi Zhu, Jie Hu, Aohan Geng, Zhenni Xu, Xueting Fang, Weijia Cheng, Yao Zhi, Yonghong Zhang, Zixin Deng, Tiangang Liu, Li Lu

Journal: Nature Communications

PubMed ID: 41213911

Doi: 10.1038/s41467-025-64842-9.

Products & Services: Protein and Antibody Isolation

On-target off-tumor toxicity of claudin18.2-directed CAR-T cells in preclinical models

Authors: Filippo Birocchi, Antonio J Almazan, Aiyana Parker, Amanda A Bouffard, Sadie Goncalves, Christopher Kelly, Jessica Frank, Mark B Leick, Nicholas J Haradhvala, Shaw Kagawa, Gad Getz, Giulia Escobar, Diego Salas-Benito, Adele Mucci, Trisha R Berger, Marcela V Maus

Journal: Nature Communications

PubMed ID: 41176533

Doi: 10.1038/s41467-025-61858-z.

Products & Services: Monoclonal Antibody Services

SLC45A4 encodes a peroxisomal putrescine transporter that promotes GABA de novo synthesis

Authors: Cecilia Colson, Yujue Wang, James Atherton, Nisha Rani Dahiya, Davood Kharaghani, Xiaoyang Su

Journal: Nature Communications

PubMed ID: 41266324

Doi: 10.1038/s41467-025-62721-x.

Products & Services: Custom Vector Construction

Generation of antigen-specific paired-chain antibodies using large language models

Authors: Perry T Wasdin, Nicole V Johnson, Alexis K Janke, Sofia Held, Toma M Marinov, Gwen Jordaan, Rebecca A Gillespie, Léna Vandenabeele, Fani Pantouli, Olivia C Powers, Matthew J Vukovich, Clinton M Holt, Jeongryeol Kim, Grant Hansman, Jennifer Logue, Helen Y Chu, Sarah F Andrews, Masaru Kanekiyo, Giuseppe A Sautto, Ted M Ross, Daniel J Sheward, Jason S McLellan, Alexandra A Abu-Shmais, Ivelin S Georgiev

Journal: Cell

PubMed ID: 41192421

Doi: 10.1016/j.cell.2025.10.006.

Products & Services: Protein and Antibody Isolation

Nivolumab plus ipilimumab induce hyper-progression in renal medullary carcinoma: results of a phase II trial and preclinical evidence

Authors: Melinda Soeung, Xinmiao Yan, Ciro Zanca, Jing Qian, Menuka Karki, Fei Duan, Hania Khan, Li Zhang, David H Peng, Mariah Williams, Rong He, Ziheng Chen, Luigi Perelli, Jianfeng Chen, Rebecca S Tidwell, Pankaj K Chauhan, Courtney N Le, Truong N A Lam, Nirjar Bhattacharya, Rutvi Shah, I-Lin Ho, Jason P Gay, Caroline C Carrillo, Ningping Feng, Kang Le, Guang Gao, Teresa L Perry, Faika Mseeh, Yongying Jiang, Quanyun A Xu, Niki Marie Zacharias, Rahul A Sheth, Tharakeswara K Bathala, Priya Rao, Najat C Daw, Durga N Tripathi, Cheryl L Walker, Mohammad M Mohammad, Jianhua Zhang, Guangchun Han, Yanshuo Chu, Ruiping Wang, Minghao Dang, Enyu Dai, Fuduan Peng, Yunhe Liu, Akshaya Jadhav, Wenhua Lang, Claudio A Arrechedera, Leticia Campos Clemente, Edwin R Parra, Hsinyi Lu, Cara L Haymaker, Ignacio I Wistuba, Andrew Futreal, Andrea Viale, Michael J Soth, Philip Jones, Joseph R Marszalek, Timothy Heffernan, Giulio F Draetta, Nizar M Tannir, Jianjun Gao, Linghua Wang, Giannicola Genovese, Pavlos Msaouel

Journal: Nature Communications

PubMed ID: 41290625

Doi: 10.1038/s41467-025-65462-z.

Products & Services: Molecular Biology Tools

Cancer-associated snaR-A noncoding RNA interacts with core splicing machinery and disrupts processing of mRNA subpopulations

Authors: Sihang Zhou, Simon Lizarazo, Sandip Chorghade, Leela Mouli, Ruiying Cheng, Rajendra K C, Auinash Kalsotra, Kevin Van Bortle

Journal: Nature Communications

PubMed ID: 41290606

Doi: 10.1038/s41467-025-65448-x.

Products & Services: Molecular Biology Reagents

A ternary switch model governing ERα ligand binding domain conformation

Authors: Daniel P McDougal, Jordan L Pederick, Scott J Novick, Blagojce Jovcevski, Annmaree K Warrender, Bruce D Pascal, Patrick R Griffin, John B Bruning

Journal: Nature Communications

PubMed ID: 41285747

Doi: 10.1038/s41467-025-65323-9.

Products & Services: Catalog Peptides

A de novo missense variant in MIDEAS results in increased deacetylase activity of the MiDAC HDAC complex causing a neurodevelopmental syndrome

Authors: Louise Fairall, Kristupas Sirvydis, Robert E Turnbull, Suzan Jg Knottnerus, Oksana Gonchar, Frederick W Muskett, Rebekah Jukes-Jones, Lonneke van Brussel, Ellen van de Geer, Koen van Gassen, Paul Badenhorst, Diana Johnson, Paulien A Terhal, Peter M van Hasselt, Richard H van Jaarsveld, John Wr Schwabe

Journal: Nature Communications

PubMed ID: 41290615

Doi: 10.1038/s41467-025-65472-x.

Products & Services: Catalog Peptides

Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity

Authors: Grzegorz P. Bereta， Ewa Bielecka， Karolina Marzec， Łukasz Pijanowski， Artur P. Biela， Piotr Wilk， Marta Kamińska， Jakub Nowak， Elżbieta Wątor-Wilk， Przemysław Grudnik， Dominik Kowalczyk， Joanna Kozieł， Piotr Mydel， Marcin Poręba， Tomasz Kantyka

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41166417

Doi: doi.org/10.1073/pnas.2508369122

Products & Services: Gene Synthesis

SmallTalk: a novel small-sized fusion tag for peptide expression and purification

Authors: Atika Tariq, Nestor G Casillas-Vega, Alma Gomez-Loredo, Xristo Zarate

Journal: FEBS Open Bio

PubMed ID: 41220226

Doi: 10.1002/2211-5463.70147

Products & Services: Gene Synthesis

Structural insights into antagonist recognition by the vasopressin V2 receptor

Authors: Tianwei Zhang, Hongli Liu, Chongzhao You, Yixiao Zhang, Youwei Xu, Benxun Pan, Canrong Wu, Sanshan Jin, Yu-Ling Yin, Kai Wu, Yue Chen, Hong Sun, Yuan Si, Yangxia Tan, Wanchao Yin, H Eric Xu, Dong Guo, Yi Jiang

Journal: Nature Communications

PubMed ID: 41188237

Doi: 10.1038/s41467-025-64735-x

Products & Services: Protein and Antibody Isolation

Anti-PD-L2 immunotherapy is efficacious against melanoma in aged hosts through IL-17 and IFNγ signalling

Authors: Carlos O Ontiveros, Myrna G Garcia, Clare E Murray, Yilun Deng, Haiyan Bai, Christopher Tanner, Bernice Leung, Xin Li, Alvaro Padron, Ryan M Reyes, Aravind Kancharla, Kah Teong Soh, Shanmugarajan Krishnan, Dhan Chand, Akshaya Balasubramanian, Courtney Hegner, Claudia V Jakubzick, Harshita B Gupta, Mary Jo Turk, Mark Sundrud, Jose R Conejo-Garcia, Tyler J Curiel

Journal: Nature Communications

PubMed ID: 41261166

Doi: 10.1038/s41467-025-65025-2.

Products & Services: CRISPR Libraries

Preclinical assessment of two FcγRI-specific antibodies that competitively inhibit immune complex-FcγRI binding to suppress autoimmune responses

Authors: Tosca Holtrop, Arianne M Brandsma, Louris J Feitsma, Steffen Krohn, Petra Moerer, Frederique van den Haak, Anouk Versnel, Leonie Voss, Elsemieke M Passchier, Maaike Nederend, J H Marco Jansen, Anouk G van Mourik, Rolf T Urbanus, Diane van der Woude, Roger E G Schutgens, Rene E M Toes, Bert J C Janssen, Anja Lux, Kevin Budding, Matthias Peipp, Jeanette H W Leusen

Journal: Nature Communications

PubMed ID: 41258113

Doi: 10.1038/s41467-025-65133-z.

Products & Services: Catalog Antibodies

Structural insight into bicarbonate-mediated carboxylation by human vitamin K-dependent carboxylase

Authors: Ke Wu, Zheng Wang, Deqiang Yao, Shaobai Li, Xiaozhu Wang, Yuanyuan Zhang, Mi Cao, Yafeng Shen, Shunpeng Xing, Jian Wu, Ming Lei, Pengfei Lan

Journal: Nature Communications

PubMed ID: 41290650

Doi: 10.1038/s41467-025-65488-3.

Products & Services: Protein and Antibody Isolation

Structural basis of regulated N-glycosylation at the secretory translocon

Authors: Melvin Yamsek, Mengxiao Ma, Roshan Jha, Yu Wan, Qianru Li, Frank Zhong, Katherine DeLong, Zhe Ji, Rajat Rohatgi, Robert J Keenan

Journal: Nature

PubMed ID: 41261126

Doi: 10.1038/s41586-025-09756-8.

Products & Services: Catalog Antibodies

ER protein CLCC1 promotes nuclear envelope fusion in herpesviral and host processes

Authors: Bing Dai, Adrian W Sperl, Lucas Polack, Isabel Mejia, Haley Dame, Tien Huynh, Chloe Deveney, Nathalie Lavoie, Chanyoung Lee, John G Doench, Matthew D Daugherty, Ekaterina E Heldwein

Journal: Nature Communications

PubMed ID: 41271665

Doi: 10.1038/s41467-025-65115-1.

Latent-TGF-β has a domain swapped architecture

Authors: Mingliang Jin, Robert I Seed, Tiffany Shing, Li Wang, Junrui Li, Yifan Cheng, Stephen L Nishimura

Journal: Nature Communications

PubMed ID: 41290649

Doi: 10.1038/s41467-025-65465-w.

Products & Services: Catalog Antibodies

Development of a cross-protective common cold coronavirus vaccine

Authors: Tanushree Dangi, Shiyi Li, Pablo Penaloza-MacMaster

Journal: Journal of virology

PubMed ID: 41123344

Doi: 10.1128/jvi.01526-25

Products & Services: Codon Optimization

Crystal structures of Ryanodine Receptor reveal dantrolene and azumolene interactions guiding inhibitor development

Authors: Hadiatullah Hadiatullah, Lianyun Lin, Zhiyan Wang, Rajamanikandan Sundarraj, Qing Wang, Xinru Lai, Nagomi Kurebayashi, Takuya Kobayashi, Toshiko Yamazawa, Yu Seby Chen, Wenlan Wang, Hongxia Zhao, Yiqing Yin, Takashi Murayama, Filip Van Petegem, Zhiguang Yuchi

Journal: Nature Communications

PubMed ID: 41253812

Doi: 10.1038/s41467-025-65096-1.

Products & Services: Protein and Antibody Isolation

Rational design of potent small-molecule SMARCA2/A4 degraders acting via the recruitment of FBXO22

Authors: Elisia Villemure, Tom Januario, Mingshuo Zeng, Hanna G Budayeva, Benjamin T Walters, Aaron Lictao, Ke Sherry Li, Xiaofen Ye, Caroline L Gilchrist, Bridget Hoag, Nicholas F Endres, Peter L Hsu, John Chan, Tommy K Cheung, Michael R Costa, Jean-Philippe Fortin, Noriko Ishisoko, Brett M Babin, Joyce Liu, Alexandra Frommlet, Joachim Rudolph, Robert L Yauch

Journal: Nature Communications

PubMed ID: 41184243

Doi: 10.1038/s41467-025-64669-4.

PCR-generated DNA templates enable efficient, rapid, and cost-effective mRNA synthesis

Authors: Naveen Kumar, Nicholas C Hazell, Jiani Bei, Tina Nguyen, Haitao Hu

Journal: Methods

PubMed ID: 40825451

Doi: 10.1016/j.ymeth.2025.08.007

Products & Services: PCR Cloning and Subcloning

De novo designed voltage-gated anion channels suppress neuron firing

Authors: Chen Zhou, Huican Li, Jiaxing Wang, Cheng Qian, Hui Xiong, Zhilin Chu, Qiming Shao, Xuan Li, Shijin Sun, Ke Sun, Aiqin Zhu, Jiawei Wang, Xueqin Jin, Fan Yang, Tamer M Gamal El-Din, Bo Li, Jing Huang, Kun Wu, Peilong Lu

Journal: Cell

PubMed ID: 41106381

Doi: 10.1016/j.cell.2025.09.023

Products & Services: Protein and Antibody Isolation

A novel low-cost and sensitive electrochemical biosensor based on Yb-protein/GO/SPE for rare earth element detection

Authors: Ting Zhang, Danni Ma, Jiaxing Gong, Bolun Sun, Fuman Cai

Journal: Sustainable Chemistry and Pharmacy

Doi: doi.org/10.1016/j.scp.2025.102248

Products & Services: Molecular Biology Reagents

Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity

Authors: Marta Alberti, Martina Tamburello, Stefano Salamone, Giorgio Gallinella, Cinzia Sanna, Giovanni Battista Appendino, Marco L Lolli, Alberto Massarotti, Federica Pollastro, Riccardo Miggiano

Journal: Journal of natural products

PubMed ID: 41143446

Doi: 10.1021/acs.jnatprod.5c00887

Products & Services: PCR Cloning and Subcloning

Simultaneous Monitoring of Intracellular Glucose and Extracellular Lactate in Single Cells to Assess Cell Tumorigenicity

Authors: Hui Liu, Yu Liu, Songqin Liu, Yafeng Wu

Journal: Analytical Chemistry

PubMed ID: 41035132

Doi: 10.1021/acs.analchem.5c03740

Products & Services: Recombinant Proteins

Structural basis for 3C and 3CD recruitment by enteroviral genomes during negative-strand RNA synthesis

Authors: Naba Krishna Das, Alisha Patel, Reem Abdelghani, Deepak Koirala

Journal: Nature Communications

PubMed ID: 41120315

Doi: doi.org/10.1038/s41467-025-64376-0

Products & Services: Codon Optimization PCR Cloning and Subcloning

Gibberellin triggers ATG8-dependent autophagic degradation of DELLA proteins to promote seed germination and skotomorphogenesis under nutrient starvation in Arabidopsis

Authors: Shilong Zhang, Lu Jiang, Huiru Chen, Huishan Liu, Minyu Xiong, Yuting Niu, Lingyi Xie, Lu Wang, Zhilei Mao, Tongtong Guo, Wenxiu Wang, Hong-Quan Yang

Journal: Molecular Plant

PubMed ID: 41108080

Doi: 10.1016/j.molp.2025.10.011

Products & Services: Catalog Antibodies

Pfs230 Domains 7–10 Encoded by DNA Vaccines Induce Potent Complement-Independent Transmission-Blocking Antibody Against Plasmodium falciparum

Authors: Yi Cao, Clifford T H Hayashi, Abhai K Tripathi, Eizo Takashima, Takafumi Tsuboi, Tucker B Harju, Nirbhay Kumar

Journal: The Journal of infectious diseases

PubMed ID: 41172338

Doi: doi.org/10.1093/infdis/jiaf555

Products & Services: PCR Cloning and Subcloning

Mycobacterium tuberculosis-specific T cells restrain anti-cancer drug-induced neutrophilic lung inflammation in tuberculosis

Authors: Kee Woong Kwon, Tae Gun Kang, Jii Bum Lee, Eunsol Choi, Hagyu Kim, Min Chul Park, Sangwon Choi, Kyungmin Kim, Hyeong Woo Kim, Su Jin Jeong, Hye Ryun Kim, Sung Jae Shin, Sang-Jun Ha

Journal: Nature Communications

PubMed ID: 41053048

Doi: 10.1038/s41467-025-63930-0

Transient rapamycin treatment avoids unwanted host immune responses toward AAV-delivered anti-HIV antibodies

Authors: Sebastian P Fuchs, Paula G Mondragon, Rachel Zabizhin, Shallu Tomer, Li Wang, Ethan Cook, Dawn M Dudley, Kimberly L Weisgrau, Jessica Furlott, Jennifer Coonen, Eric Alexander, Jun Xie, Guangping Gao, James M Termini, Jose M Martinez-Navio, Anjie Zhen, Ronald C Desrosiers

Journal: Nature Communications

PubMed ID: 41057323

Doi: 10.1038/s41467-025-63970-6

RNA replicon vaccination confers long-lasting protection against H5N1 avian influenza in 23 zoo bird species

Authors: Marion Stettler, Stefan Hoby, Christian Wenker, Fabia Wyss, Elisabeth Heiderich, Lisa Butticaz, Nicolas Ruggli, Karin Darpel & Gert Zimmer

Journal: Nature Communications

PubMed ID: 41115934

Doi: 10.1038/s41467-025-64301-5

Products & Services: Protein Electrophoresis and Western

Targeted degradation of endogenous YAP by nanobody bioPROTAC inhibits tumor progression

Authors: Runhua Zhou, Huifang Wang, Gui-Ming Zhang, Yawei Liu, Xiao-Lian Liu, Zhifen Li, Guangwei Shi, Junling Yuan, Chengming Qu, Yang Li, Liang Chen, Jingnan Huang, Hongchao Zhou, Lingyun Dai, Chongzhi Bai, Jigang Wang, Le Yu, Zhijie Li & Yi-Lei Li

Journal: Nature Communications

PubMed ID: 41130953

Doi: 10.1038/s41467-025-64426-7

Products & Services: Catalog Antibodies

Metabolic regulation of behavior by the intestinal enzyme FMO-2

Authors: Elizabeth S Kitto, Safa Beydoun, Ella Henry, Megan L Schaller, Mira Bhandari, Sarah A Easow, Angela M Tuckowski, Marshall B Howington, Ajay Bhat, Aditya Sridhar, Eugene Chung, Charles R Evans, Scott F Leiser

Journal: SCIENCE ADVANCES

PubMed ID: 41134904

Doi: 10.1126/sciadv.adx3018

Products & Services: Recombinant Proteins

Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks

Authors: Brandon T. Malady, Andromachi Papagiannoula, Advika Kamatar, Susovan Sarkar, Gavin T. Lebrun, Liping Wang, Carl C. Hayden, Eileen M. Lafer, David J. Owen, Sigrid Milles & Jeanne C. Stachowiak

Journal: Nature Communications

PubMed ID: 41093888

Doi: 10.1038/s41467-025-64816-x

Journal of Controlled Release

Authors: Fei Li, Quan Wang, Tingting Wang, Chen Xiong, Ziling Chen, Hanzhi Ouyang, Xiaoding Lou, Fan Xia, Shixuan Wang, Meng Wu, Jun Dai

Journal: Journal of controlled release

Doi: 10.1016/j.jconrel.2025.114337

Products & Services: Plasmid DNA Preparation

A Robust, High-Titer, Semi-Automated, and In-Culture Antibody-Capturing Transient CHO Platform Technology

Authors: Lauren Gebhardt, Molica Abel, Jing Zhou, Audrey M Vogt, Bo Hee Shin, Sarah L Herrick Wagman, Ana Santos, Jerome Puginier, Florian M Wurm, Maria J Wurm, Guoying Grace Yan, Adedolapo Adeniyi, Sean K H Lim, Will Somers, Laura Lin, Aaron M D'Antona, Xiaotian Zhong

Journal: Antibodies

PubMed ID: 41133681

Doi: 10.3390/antib 14040087

Products & Services: Protein and Antibody Isolation

SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade

Authors: Adam J. Grippin, Christiano Marconi, Sage Copling, Nan Li, Chen Braun, Cole Woody, Elliana Young, Priti Gupta, Min Wang, Annette Wu, Seong Dong Jeong, Dhruvkumar Soni, Frances Weidert, Chao Xie, Eden Goldenberg, Andrew Kim, Chong Zhao, Anna DeVries, Paul Castillo, Rishabh Lohray, Michael K. Rooney, Benjamin R. Schrank, Yifan Wang, Yifan Ma, D3CODE Team, …Steven H. Lin

Journal: Nature

PubMed ID: 41125896

Doi: 10.1038/s41586-025-09655-y

αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility in mouse models

Authors: Tianci Wang, Yupu Xu, Zhengfeng Zhang, Yaqi Wu, Long Chen, Xiaodong Zheng, Hui Peng, Qiang Zou, Rui Sun, Hongdi Ma, Haoyu Sun, Zhigang Tian & Xiaohu Zheng

Journal: Nature Communications

PubMed ID: 41107262

Doi: 10.1038/s41467-025-64296-z

Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins

Authors: Thapakorn Jaroentomeechai, Billy Veloz, Cátia O Soares, Felix Goerdeler, Ana Sofia Grosso, Christian Büll, Rebecca L Miller, Sanae Furukawa, Irene Ginés-Alcober, Víctor Taleb, Pedro Merino, Mattia Ghirardello, Ismael Compañón, Helena Coelho, Jorge S Dias, Renaud Vincentelli, Bernard Henrissat, Hiren Joshi, Henrik Clausen, Francisco Corzana, Filipa Marcelo, Ramon Hurtado-Guerrero, Yoshiki Narimatsu

Journal: Nature Communications

PubMed ID: 41083434

Doi: 10.1038/s41467-025-63756-w

Baculovirus-Mediated Gene Therapy: Targeting BIRC6 for Lung and Breast Cancer

Authors: Abril Marchesini, Santiago M Gómez Bergna, Leslie C Amorós Morales, María Florencia López, Larisa Vásquez, Silvana E Tongiani, Florencia González Morán, Víctor Romanowski, María Florencia Gottardo, Matias L Pidre

Journal: Viruses

PubMed ID: 41305480

Doi: 10.3390/v17111458

Products & Services: PCR Cloning and Subcloning Plasmid DNA Preparation

DLFea4AMPGen de novo design of antimicrobial peptides by integrating features learned from deep learning models

Authors: Han Gao, Feifei Guan, Boyu Luo, Dongdong Zhang, Wei Liu, Yuying Shen, Lingxi Fan, Guoshun Xu, Yuan Wang, Tao Tu, Ningfeng Wu, Bin Yao, Huiying Luo, Yue Teng, Jian Tian, Huoqing Huang

Journal: Nature Communications

PubMed ID: 41093853

Doi: 10.1038/s41467-025-64378-y

A human-specific regulatory mechanism revealed in a pre-implantation model

Authors: Raquel Fueyo, Sicong Wang, Olivia J. Crocker, Tomek Swigut, Hiromitsu Nakauchi & Joanna Wysocka

Journal: Nature

PubMed ID: 41034587

Doi: 10.1038/s41586-025-09571-1

Mechanism-based peroxiredoxin 3 inhibitors exploit a covalent warhead for cancer therapy

Authors: Kimberly J Nelson, Terrence L Smalley Jr, Terri Messier, Rajesh Gumpena, Uma Gandhi, Stephanie Milczarek, Aida Habibovic, Hattie Hoffman, Victoria Gibson, Robert J Hondal, W Todd Lowther, Brian Cunniff

Journal: SCIENCE ADVANCES

PubMed ID: 41171914

Doi: 41171914

Virus-inspired lipopeptide-derived nucleic acid delivery to cartilage for osteoarthritis therapy

Authors: Yu Fu, Yulan Huang, Yunjiao Wang, Zhenlan Fu, Wenyun Cai, Lu Wang, Yuchun Wu, Xing Zhou, Zhongyi Ma, Zhigang Xu, Yaqin Tang, Jing Xie, Jiayun Jiang, Robert J. Lee & Chong Li

Journal: Nature Communications

PubMed ID: 41102140

Doi: 10.1038/s41467-025-64212-5

The nuclear import receptor importin-7 targets HPV from the Golgi to the nucleus to promote infection

Authors: Tai-Ting Woo, Yuka Takeo, Mara C Harwood, Ethan T Houck, Daniel DiMaio, Billy Tsai

Journal: SCIENCE ADVANCES

PubMed ID: 41124246

Doi: 10.1126/sciadv.adz6792

DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage

Authors: Zihui Yan, Guanjin Qu, Xin Chen, Gang Zheng & Huaming Wu

Journal: Nature Communications

PubMed ID: 41102205

Doi: 10.1038/s41467-025-64230-3

Discovery of a Serine-Directed Chemical Reaction for Site-Specific Protein Modification via Phage Display Screening

Authors: Yingjie Lei, Kai Zhao, Mengzhun Guo, Liang Guo, Jinfeng Chen, Mengjiao Li, Dandan Liu, Kai Chen, Jiahao Mei, Tian Li, Bing Yang, Jing Huang, Bobo Dang

Journal: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PubMed ID: 41108661

Doi: doi.org/10.1002/anie.202514412

Products & Services: Protein and Antibody Isolation

ROS-triggered self-assembling peptide hydrogel combining bacterial entrapment and intracellular penetration for Salmonella Typhimurium-induced enteritis therapy

Authors: Wenwen Meng, Hao Yang, Wenqian Zhang, Xueyan Li, Jiajun Sun, Ting Hu, Wei Li, Yaohong Zhu, Yong Wang, Xi Ma, Guiyan Yang, Jiufeng Wang

Journal: Chemical Engineering Journal

Doi: doi.org/10.1016/j.cej.2025.169392

Products & Services: Peptide Synthesis

Noncanonical target-strand cytosine base editing via engineered Un1Cas12f1 platform

Authors: Ziguo Song, Junfan Guo, Zhanqing Fan, Shuhong Huang, Guanglei Li, Zichang Zhao, Bingchun Chen, Shisheng Huang, Wenxin Zheng, Yinghui Wei, Yulin Chen, Xingxu Huang, Jianghuai Liu, Lina Wu, Xiaolong Wang

Journal: Nature Communications

PubMed ID: 41152217

Doi: 10.1038/s41467-025-64562-0

Products & Services: Plasmid DNA Preparation

Metal fluoride nanoregulators reverse therapeutic resistance via stemness remodeling to trigger pyroptosis for chemoimmunotherapy

Authors: Shumin Sun, Nailin Yang, Jihu Nie, Linzhu Zhang, Di Wang, Xingwei Sun, Yong Jin, Liang Cheng

Journal: Bioactive Materials

PubMed ID: 41211577

Doi: 10.1016/j.bioactmat.2025.10.011

Products & Services: Protein and Antibody Isolation

Arabidopsis response to the apocarotenoid zaxinone involves interference with strigolactone signaling via binding to DWARF14

Authors: Juan C Moreno, Umar F Shahul Hameed, Aparna Balakrishna, Abdugaffor Ablazov, Kit Xi Liew, Muhammad Jamil, Jianing Mi, Kawthar Alashoor, Alexandre de Saint Germain, Stefan T Arold, Salim Al-Babili

Journal: Nature Communications

PubMed ID: 41038837

Doi: 10.1038/s41467-025-63845-w

Non-canonical dihydrolipoyl transacetylase promotes chemotherapy resistance via mitochondrial tetrahydrofolate signaling

Authors: Jung Seok Hwang, JiHoon Kang, Jaehyun Kim, Kiyoung Eun, Sophia West, Hannah E Bacho, Vanessa Avalos, Sydney Shuff, Dong M Shin, Nabil F Saba, Kelly R Magliocca, Cheng-Kui Qu, Haian Fu, Suresh S Ramalingam, Andrey A Ivanov, Taro Hitosugi, Sumin Kang

Journal: Nature Communications

PubMed ID: 41062483

Doi: 10.1038/s41467-025-63892-3

Metabolic Hijacking by Engineered Probiotics Reprograms Tumor Metabolism and Immune Microenvironment for Self-Reinforcing Photodynamic Immunotherapy

Authors: Shurong Qin, Qi Wang, Zhuangwei Zhang, Junhui Gu, Guanzhong He, Fei Zeng, Ruiyue Chen, Bangshun He, Yuzhen Wang, Meng Wang, Yujun Song

Journal: Journal of the American Chemical Society

PubMed ID: 41059938

Doi: 10.1021/jacs.5c10242

Products & Services: Recombinant Proteins

ZBP1 pathway promotes tumor immunogenicity in thecombinationofanti-HER2therapyandepigenetic therapy

Authors: Qishan Wang, Zhihao Wu, Yuanqin Yang, Chao Yang, Haoran Deng, Xingyue Zhou, Shuting Xu, Lingling Wu, Xiaochuan Hong, Xueni Yu, Lu Lu, Liufu Deng

Journal: Cell Reports

Doi: 10.1016/j.celrep.2025.116314

Products & Services: Protein Electrophoresis and Western