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Fungi of the order Mucorales express a "sealing-only" tRNA ligase

Authors: Khondakar Sayef Ahammed, Ambro van Hoof

Journal: biorxiv

PubMed ID: 38014270

Doi: 10.1101/2023.11.16.567474

Products & Services: Molecular Biology Reagents

Specifications of qPCR based epigenetic immune cell quantification

Authors: Konstantin Schildknecht, Björn Samans, Jasmin Gussmann, Udo Baron, Eva Raschke, Nina Babel, Julia Oppatt, Katharina Gellhaus, Araceli Rossello, Isabell Janack, Sven Olek

Journal: Clin Chem Lab Med

PubMed ID: 37982750

Doi: 10.1515/cclm-2023-1056

Products & Services: Molecular Biology Reagents

Peptide Amphiphiles as Biodegradable Adjuvants for Efficient Retroviral Gene Delivery

Authors: Kübra Kaygisiz, Lena Rauch-Wirth, Aysenur Iscen, Jan Hartenfels, Kurt Kremer, Jan Münch, Christopher V Synatschke, Tanja Weil

Journal: Adv Healthc Mater

PubMed ID: 37947246

Doi: 10.1002/adhm.202301364

Products & Services: Gene Synthesis

Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

Authors: Ali Ghasemi, Amaia Martinez-Usatorre, Luqing Li, Mehdi Hicham, Alan Guichard, Rachel Marcone, Nadine Fournier, Bruno Torchia, Darel Martinez Bedoya, Suzel Davanture, Mirian Fernández-Vaquero, Chaofan Fan, Jakob Janzen, Yahya Mohammadzadeh, Raphael Genolet, Nahal Mansouri, Mathias Wenes, Denis Migliorini, Mathias Heikenwalder, Michele De Palma

Journal: Nat Cancer

PubMed ID: 37996514

Doi: 10.1038/s43018-023-00668-y

Products & Services: PCR Cloning and Subcloning

Oxidative stress and signaling through EGFR and PKA pathways converge on the nuclear transport factor RanBP1

Authors: Mohamed Kodiha, Nabila Azad, Siwei Chu, Noah Crampton, Ursula Stochaj

Journal: Eur J Cell Biol

PubMed ID: 38011756

Doi: 10.1016/j.ejcb.2023.151376

Products & Services: Codon Optimization

Abundant binary promoter switches in lineage-determining transcription factors indicate a digital component of cell fate determination

Authors: Hongchuan Li, Md Ahasanur Rahman, Michael Ruesch, Caprice D Eisele, Erik M Anderson, Paul W Wright, Jennie Cao, Shashikala Ratnayake, Qingrong Chen, Chunhua Yan, Daoud Meerzaman, Roshini S Abraham, Aharon G Freud, Stephen K Anderson

Journal: Cell Rep

PubMed ID: 37976160

Doi: 10.1016/j.celrep.2023.113454

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Circulating extracellular choline acetyltransferase regulates inflammation

Authors: Arielle H Gabalski, Aisling Tynan, Tea Tsaava, Jian Hua Li, Diana Lee, Tyler D Hepler, Daniel Hide, Sam George, Carlos E Bravo Iñiguez, Dane A Thompson, Cassie Zhu, Haichao Wang, Michael Brines, Kevin J Tracey, Sangeeta S Chavan

Journal: J Intern Med

PubMed ID: 38011942

Doi: 10.1111/joim.13750

Products & Services: Catalog Antibody

Nanopore Signatures of Nucleoside Drugs

Authors: Wendong Jia , Yusheng Ouyang , Shanyu Zhang , Xiaoyu Du , Panke Zhang , Shuo Huang

Journal: Nano Lett .

PubMed ID: 37818841

Doi: 10.1021/acs.nanolett.3c02872

Products & Services: Plasmid DNA Preparation

A chlorophyll c synthase widely co-opted by phytoplankton

Authors: Yanyou Jiang , Tianjun Cao , Yuqing Yang , Huan Zhang , Jingyu Zhang , Xiaobo Li

Journal: Science .

PubMed ID: 37797009

Doi: 10.1126/science.adg7921

Products & Services: Gene Synthesis

HDL mimetics protect Alzheimer’s patients carrying APOE ε4 from SARS-CoV-2 invasion

Authors: Ruodan Xu , Junwei Gao , Can Cao , Mingfei Shi , Yonghui Zhang , Shihao Hong , Shijie Guo , Menglin Chen , Ping Song , Gaoshuang Fu , Jing Li , Tengxiao Liang , Yingchun Miao , Lu Tang , Jinsheng Yang , Ning Li , Mingdong Dong

Journal: Nano Today

Doi: 10.1016/j.nantod.2023.102051

Products & Services: Gene Synthesis Peptide Synthesis

Development and characterization of anti-IL-5 monoclonal antibody Fab fragment for blocking IL-5/IL-5Rα binding

Authors: Shijie Li , Shijie Wang , Eric Fordjour , Yaoji Liang , Xuelian Wang , Yonghao Ye , Zhonghu Bai , Yankun Yang , Yongqi Chen

Journal: International Immunopharmacology

Doi: 10.1016/j.intimp.2023.111032

Products & Services: Gene Synthesis Peptide Synthesis

Architecture and rearrangements of a sperm-specific Na/H exchanger

Authors: Sandipan Chowdhury, Kamalendu Pal

Journal: Res Sq

PubMed ID: 37886505

Doi: 10.21203/rs.3.rs-3396005/v1

Products & Services: Proteins, Expression, Isolation and Analysis

Extract2Chip-Bypassing Protein Purification in Drug Discovery Using Surface Plasmon Resonance

Authors: Ana C F Paiva, Ana R Lemos, Philipp Busse, Madalena T Martins, Diana O Silva, Micael C Freitas, Sandra P Santos, Filipe Freire, Evelyne J Barrey, Xavier Manival, Lisa Koetzner, Timo Heinrich, Ansgar Wegener, Ulrich Grädler, Tiago M Bandeiras, Daniel Schwarz, Pedro M F Sousa

Journal: Biosensors (Basel)

PubMed ID: 37887106

Doi: 10.3390/bios13100913

Products & Services: Proteins, Expression, Isolation and Analysis

Collagen Mimetic Peptide with a Coiled Coil Trimerization Domain Forms Fibrils Having -Period-like Structures

Authors: Faizunnahar Dewan, Michele Kirchner, Fadi Masoud, Zainab Sami, Yujia Xu

Journal: Biomacromolecules

PubMed ID: 37788665

Doi: 10.1021/acs.biomac.3c00901

Products & Services: Molecular Biology Reagents

Pyruvate kinase is post-translationally regulated by sirtuin 2 in Aedes aegypti mosquitoes

Authors: Natthida Petchampai, Jun Isoe, Prashanth Balaraman, Max Oscherwitz, Brendan H Carter, Cecilia G Sánchez, Patricia Y Scaraffia

Journal: Insect Biochem Mol Biol

PubMed ID: 37797713

Doi: 10.1016/j.ibmb.2023.104015

Products & Services: Molecular Biology Reagents

Influence of expression and purification protocols on Gα biochemical activity: kinetics of plant and mammalian G protein cycles

Authors: Timothy E Gookin, David Chakravorty, Sarah M Assmann

Journal: biorxiv

PubMed ID: 37214830

Doi: 10.1101/2023.05.10.540258

Products & Services: Molecular Biology Reagents

Ceria Nanozyme Coordination with Curcumin for Treatment of Sepsis-induced Cardiac Injury by Inhibiting Ferroptosis and Inflammation

Authors: Chenxiao Jiang, Qianzhi Shi, Jing Yang, Hao Ren, Lu Zhang, Shan Chen, Jiayi Si, Yihai Liu, Dujuan Sha, Biao Xu, Jie Ni

Journal: J Adv Res

PubMed ID: 37871772

Doi: 10.1016/j.jare.2023.10.011

Products & Services: PCR Cloning and Subcloning

Biochemical and structural characterization of a glucan synthase GFGLS2 from edible fungus Grifola frondosa to synthesize β-1, 3-glucan

Authors: Yu-Meng Yang, Xin Fu, Feng-Jie Cui, Lei Sun, Xin-Yi Zan, Wen-Jing Sun

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 37904199

Doi: 10.1186/s13068-023-02380-6

Products & Services: Codon Optimization

A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity

Authors: Andras Boeszoermenyi, Léa Bernaleau, Xudong Chen, Felix Kartnig, Min Xie, Haobo Zhang, Sensen Zhang, Maeva Delacrétaz, Anna Koren, Ann-Katrin Hopp, Vojtech Dvorak, Stefan Kubicek, Daniel Aletaha, Maojun Yang, Manuele Rebsamen, Leonhard X Heinz, Giulio Superti-Furga

Journal: Nat Commun

PubMed ID: 37863876

Doi: 10.1038/s41467-023-42070-3

Products & Services: Plasmid DNA Preparation

Serpin-1a and serpin-6 regulate the Toll pathway immune homeostasis by synergistically inhibiting the Spätzle-processing enzyme CLIP2 in silkworm, Bombyx mori

Authors: Huawei Liu, Jiahui Xu, Luoling Wang, Pengchao Guo, Zhangchen Tang, Xiaotong Sun, Xin Tang, Wei Wang, Lingyan Wang, Yang Cao, Qingyou Xia, Ping Zhao

Journal: PLoS Pathog

PubMed ID: 37851691

Doi: 10.1371/journal.ppat.1011740

Products & Services: Peptide Synthesis

KRAS G12V neoantigen specific T cell receptor for adoptive T cell therapy against tumors

Authors: Dan Lu, Yuan Chen, Min Jiang, Jie Wang, Yiting Li, Keke Ma, Wenqiao Sun, Xing Zheng, Jianxun Qi, Wenjing Jin, Yu Chen, Yan Chai, Catherine W H Zhang, Hao Liang, Shuguang Tan, George F Gao

Journal: Nat Commun

PubMed ID: 37828002

Doi: 10.1038/s41467-023-42010-1

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Distribution and Degradation of Pork Filamin during Postmortem Aging

Authors: Tongyao Du, Chao Ma, Zixu Wang, Yuejing Hao, Wangang Zhang

Journal: J Agric Food Chem

PubMed ID: 37788342

Doi: 10.1021/acs.jafc.3c04208

Products & Services: Proteins, Expression, Isolation and Analysis

Benzbromarone Induces Targeted Degradation of HSP47 Protein and Improves Hypertrophic Scar Formation

Authors: Jung Gyu Park, Dong Chul Lim, Jeong Hwan Park, Seoah Park, Jongsoo Mok, Keon Wook Kang, Joonghoon Park

Journal: J Invest Dermatol

PubMed ID: 37838329

Doi: 10.1016/j.jid.2023.09.279

Products & Services: Recombinant Proteins

Molecular mechanism of sex pheromone perception in male Mythimna loreyi revealed by in vitro system

Authors: Yun-Ying Zhang, Teng-Fei Bai, Jin-Meng Guo, Zhi-Qiang Wei, Si-Ruo Liu, Yu He, Jing-Jing Ye, Qi Yan, Jin Zhang, Shuang-Lin Dong

Journal: Pest Manag Sci

PubMed ID: 37779104

Doi: 10.1002/ps.7806

Products & Services: Recombinant Proteins

How myosin VI traps its off-state, is activated and dimerizes

Authors: Louise Canon , Carlos Kikuti , Vicente J Planelles-Herrero , Tianming Lin , Franck Mayeux , Helena Sirkia , Young Il Lee , Leila Heidsieck , Léonid Velikovsky , Amandine David , Xiaoyan Liu ， Dihia Moussaoui , Emma Forest , Peter Höök , Karl J Petersen , Tomos E Morgan , Aurélie Di Cicco , Julia Sirés-Campos , Emmanuel Derivery , Daniel Lévy , Cédric Delevoye , H Lee Sweeney , Anne Houdusse

Journal: Nat Commun

PubMed ID: 37872146

Doi: 10.1038/s41467-023-42376-2

Products & Services: PCR Cloning and Subcloning

m6A methyltransferase METTL3 contributes to sympathetic hyperactivity post-MI via promoting TRAF6-dependent mitochondrial ROS production

Authors: Peijin Yang, Yu Wang, Weili Ge, Yanyan Jing, Hesheng Hu, Jie Yin, Mei Xue, Ye Wang, Xiaolu Li, Xinran Li, Yugen Shi, Jiayu Tan, Yan Li, Suhua Yan

Journal: Free Radic Biol Med

PubMed ID: 37898386

Doi: 10.1016/j.freeradbiomed.2023.10.392

Products & Services: Proteins, Expression, Isolation and Analysis

Single-cell chromatin state transitions during epigenetic memory formation

Authors: Taihei Fujimori, Carolina Rios-Martinez, Abby R Thurm, Michaela M Hinks, Benjamin R Doughty, Joydeb Sinha, Derek Le, Antonina Hafner, William J Greenleaf, Alistair N Boettiger, Lacramioara Bintu

Journal: biorxiv

PubMed ID: 37873344

Doi: 10.1101/2023.10.03.560616

Products & Services: Proteins, Expression, Isolation and Analysis

Entropy-driven reactions for controlling CRISPR/Cas12a and constructing an electrochemical biosensor for cardiac biomarkers detection

Authors: Jiaying Wang, Xianliang Wang, Bin Li, Kai Zhang, Jingyuan Mao

Journal: Mikrochim Acta

PubMed ID: 37845542

Doi: 10.1007/s00604-023-06012-6

Products & Services: Proteins, Expression, Isolation and Analysis

A retrospective study of SARS-CoV-2 seroprevalence in dogs and cats in the Community of Madrid, Spain

Authors: Lidia Sánchez-Morales, José M Sánchez-Vizcaíno, Lucas Domínguez, Sandra Barroso-Arévalo

Journal: Front Microbiol

PubMed ID: 37869682

Doi: 10.3389/fmicb.2023.1264172

Products & Services: Proteins, Expression, Isolation and Analysis

Functional dissection and assembly of a small, newly evolved, W chromosome-specific genomic region of the African clawed frog Xenopus laevis

Authors: Caroline M S Cauret, Danielle C Jordan, Lindsey M Kukoly, Sarah R Burton, Emmanuela U Anele, Jacek M Kwiecien, Marie-Theres Gansauge, Sinthu Senthillmohan, Eli Greenbaum, Matthias Meyer, Marko E Horb, Ben J Evans

Journal: PLoS Genet

PubMed ID: 37792893

Doi: 10.1371/journal.pgen.1010990

Products & Services: Proteins, Expression, Isolation and Analysis

A dry powder formulation for peripheral lung delivery and absorption of an anti-SARS-CoV-2 ACE2 decoy polypeptide

Authors: Stefania Glieca, Davide Cavazzini, Elisabetta Levati, Valentina Garrapa, Angelo Bolchi, Valentina Franceschi, Simone Odau, Simone Ottonello, Gaetano Donofrio, Jonas Füner, Fabio Sonvico, Ruggero Bettini, Barbara Montanini, Francesca Buttini

Journal: Eur J Pharm Sci

PubMed ID: 37838239

Doi: 10.1016/j.ejps.2023.106609

Products & Services: Proteins, Expression, Isolation and Analysis

Creating Designer Engineered Extracellular Vesicles for Diverse Ligand Display, Target Recognition, and Controlled Protein Loading and Delivery

Authors: Alena Ivanova, Lukas Badertscher, Gwen O'Driscoll, Joakim Bergman, Euan Gordon, Anders Gunnarsson, Camilla Johansson, Michael J Munson, Cristiana Spinelli, Sara Torstensson, Liisa Vilén, Andrei Voirel, John Wiseman, Janusz Rak, Niek Dekker, Elisa Lázaro-Ibáñez

Journal: Adv Sci (Weinh)

PubMed ID: 37867228

Doi: 10.1002/advs.202304389

Products & Services: Proteins, Expression, Isolation and Analysis

Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors

Authors: Xiuxiu Zhu, Jun Chen, Wuling Li, Yanmin Xu, Juanjuan Shan, Juan Hong, Yongchun Zhao, Huailong Xu, Jiabing Ma, Junjie Shen, Cheng Qian

Journal: Cancer Res

PubMed ID: 37874330

Doi: 10.1158/0008-5472.CAN-23-1038

Products & Services: Proteins, Expression, Isolation and Analysis

X-ray crystallography study and optimization of novel benzothiophene analogs as potent selective estrogen receptor covalent antagonists (SERCAs) with improved potency and safety profiles

Authors: Chengfeng Bai, Yang Lv, Shuangshuang Xiong, Shuangjie Wu, Lin Qi, Shengnan Ren, Meiqi Zhu, Haijuan Dong, Hongtao Shen, Zhaoxing Li, Yinxue Zhu, Hui Ye, Haiping Hao, Yibei Xiao, Hua Xiang, Guoshun Luo

Journal: Bioorg Chem

PubMed ID: 37871388

Doi: 10.1016/j.bioorg.2023.106919

Products & Services: Proteins, Expression, Isolation and Analysis

CTNNBIP1-CLSTN1 functions as a housekeeping chimeric RNA and regulates cell proliferation through SERPINE2

Authors: Chen Chen, Fujun Qin, Sandeep Singh, Yue Tang, Hui Li

Journal: Cell Death Discov

PubMed ID: 37805599

Doi: 10.1038/s41420-023-01668-8

Products & Services: Proteins, Expression, Isolation and Analysis

becomes lethal to post-larvae shrimp via acquiring novel virulence factors

Authors: Shuang Liu, Wei Wang, Tianchang Jia, Lusheng Xin, Ting-Ting Xu, Chong Wang, Guosi Xie, Kun Luo, Jun Li, Jie Kong, Qingli Zhang

Journal: Microbiol Spectr

PubMed ID: 37850796

Doi: 10.1128/spectrum.00492-23

Products & Services: Proteins, Expression, Isolation and Analysis

Ablation of the GDP-fucose transporter suppresses lung cancer cell proliferation and migration by reducing expression of PD-L1

Authors: Yingshu Zhang, Nianzhu Zhang, Wanli Song, Sabiha Yousuf, Wenzhe Li

Journal: J Cancer

PubMed ID: 37928424

Doi: 10.7150/jca.84652

Products & Services: Proteins, Expression, Isolation and Analysis

generated antibodies guide thermostable ADDomer nanoparticle design for nasal vaccination and passive immunization against SARS-CoV-2

Authors: Dora Buzas, Adrian H Bunzel, Oskar Staufer, Emily J Milodowski, Grace L Edmunds, Joshua C Bufton, Beatriz V Vidana Mateo, Sathish K N Yadav, Kapil Gupta, Charlotte Fletcher, Maia K Williamson, Alexandra Harrison, Ufuk Borucu, Julien Capin, Ore Francis, Georgia Balchin, Sophie Hall, Mirella V Vega, Fabien Durbesson, Srikanth Lingappa, Renaud Vincentelli, Joe Roe, Linda Wooldridge, Rachel Burt, Ross J L Anderson, Adrian J Mulholland, Jonathan Hare, Mick Bailey, Andrew D Davidson, Adam Finn, David Morgan, Jamie Mann, Joachim Spatz, Frederic Garzoni, Christiane Schaffitzel, Imre Berger

Journal: Antib Ther

PubMed ID: 38075238

Doi: 10.1093/abt/tbad024

Products & Services: Molecular Biology Reagents

Vaccination with post-translational modified, homocitrullinated peptides induces CD8 T-cell responses that mediate antitumor immunity

Authors: Sabaria Shah, Katherine W Cook, Peter Symonds, Juliane Weißer, Anne Skinner, Abdullah Al Omari, Samantha J Paston, Ian Pike, Lindy G Durrant, Victoria A Brentville

Journal: J Immunother Cancer

PubMed ID: 37857526

Doi: 10.1136/jitc-2023-006966

Products & Services: Peptide Synthesis

Enhanced protective efficacy of a thermostable RBD-S2 vaccine formulation against SARS-CoV-2 and its variants

Authors: Nidhi Mittal, Sahil Kumar, Raju S Rajmani, Randhir Singh, Céline Lemoine, Virginie Jakob, Sowrabha Bj, Nayana Jagannath, Madhuraj Bhat, Debajyoti Chakraborty, Suman Pandey, Aurélie Jory, Suba Soundarya Sa, Harry Kleanthous, Patrice Dubois, Rajesh P Ringe, Raghavan Varadarajan

Journal: npj Vaccines

PubMed ID: 37880298

Doi: 10.1038/s41541-023-00755-2

Products & Services: Proteins, Expression, Isolation and Analysis

Plant miRNA bol-miR159 Regulates Gut Microbiota Composition in Mice: Evidence of the Crosstalk between Plant miRNAs and Intestinal Microbes

Authors: Qin Xu, Xinshu Qin, Yi Zhang, Ke Xu, Ying Li, Yinglei Li, Bangran Qi, Yan Li, Xingbin Yang, Xingyu Wang

Journal: J Agric Food Chem

PubMed ID: 37862127

Doi: 10.1021/acs.jafc.3c06104

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Functional characterization of a lytic polysaccharide monooxygenase from Schizophyllum commune that degrades non-crystalline substrates

Authors: Heidi Østby, Idd A Christensen, Karen Hennum, Anikó Várnai, Edith Buchinger, Siri Grandal, Gaston Courtade, Olav A Hegnar, Finn L Aachmann, Vincent G H Eijsink

Journal: Sci Rep

PubMed ID: 37833388

Doi: 10.1038/s41598-023-44278-1

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Emergent properties of melanin-inspired peptide/RNA condensates

Authors: Amit Netzer, Itai Katzir, Avigail Baruch Leshem, Michal Weitman, Ayala Lampel

Journal: Proc Natl Acad Sci U S A

PubMed ID: 37871222

Doi: 10.1073/pnas.2310569120

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CD8 T-cells target the Crimean-Congo haemorrhagic fever virus Gc protein to control the infection in wild-type mice

Authors: Deepashri Rao, Kimberly Meade-White, Shanna Leventhal, Evan Mihalakakos, Aaron Carmody, Heinz Feldmann, David W Hawman

Journal: EBioMedicine

PubMed ID: 37866114

Doi: 10.1016/j.ebiom.2023.104839

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A biotechnological approach for the production of new protein bioplastics

Authors: Francesca De Marchis, Tania Vanzolini, Elisa Maricchiolo, Michele Bellucci, Michele Menotta, Tomas Di Mambro, Annalisa Aluigi, Andrea Zattoni, Barbara Roda, Valentina Marassi, Rita Crinelli, Andrea Pompa

Journal: Biotechnol J

PubMed ID: 37801630

Doi: 10.1002/biot.202300363

Products & Services: Molecular Biology Reagents

Inhibition of N-myristoyltransferase activity promotes androgen receptor degradation in prostate cancer

Authors: Omar Awad Alsaidan, Emmanuel Onobun, Chenming Ye, Lei Lou, Zanna Beharry, Zhong-Ru Xie, Iryna Lebedyeva, David Crich, Houjian Cai

Journal: Prostate

PubMed ID: 37905842

Doi: 10.1002/pros.24645

Products & Services: Molecular Biology Reagents

RING induces cell cycle arrest and apoptosis in human breast cancer cells by regulating the HSF1/MT2A axis

Authors: Di Liu, Yize Guo, Qin Du, Yuxuan Zhu, Ya Guo

Journal: Exp Cell Res

PubMed ID: 37797799

Doi: 10.1016/j.yexcr.2023.113795

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Investigation of serum amyloid a within animal species focusing on the 1-25 amino acid region

Authors: Natalie G Horgan, Kendall B E Moore, Jessica S Fortin

Journal: Vet Q

PubMed ID: 37800590

Doi: 10.1080/01652176.2023.2267605

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Recovery of protein synthesis to assay DNA repair activity in transcribed genes in living cells and tissues

Authors: Melanie van der Woude, Carlota Davó-Martínez, Karen L Thijssen, Wim Vermeulen, Hannes Lans

Journal: Nucleic Acids Res

PubMed ID: 37522336

Doi: 10.1093/nar/gkad642

Products & Services: Proteins, Expression, Isolation and Analysis

Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer's disease

Authors: Xingyu Zhang, Li Tang, Jiaolong Yang, Lanxia Meng, Jiehui Chen, Lingyan Zhou, Jiangyu Wang, Min Xiong, Zhentao Zhang

Journal: Nat Commun

PubMed ID: 37865646

Doi: 10.1038/s41467-023-42505-x

Products & Services: Proteins, Expression, Isolation and Analysis

Dihydropyrmidine dehydrogenase from Escherichia coli: Transient state analysis reveals both reductive activation prior to turnover and diminished substrate effector roles relative to the mammalian form

Authors: Tyler B Alt, Matthew R Hoag, Graham R Moran

Journal: Arch Biochem Biophys

PubMed ID: 37820757

Doi: 10.1016/j.abb.2023.109772

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular mechanism of decision-making in glycosaminoglycan biosynthesis

Authors: Douglas Sammon, Anja Krueger, Marta Busse-Wicher, Rhodri Marc Morgan, Stuart M Haslam, Benjamin Schumann, David C Briggs, Erhard Hohenester

Journal: Nat Commun

PubMed ID: 37828045

Doi: 10.1038/s41467-023-42236-z

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High-risk histological subtype-related FAM83A hijacked FOXM1 transcriptional regulation to promote malignant progression in lung adenocarcinoma

Authors: Wei Fei, Yan Yan, Guangjun Liu, Bo Peng, Yuanyuan Liu, Qiang Chen

Journal: PeerJ

PubMed ID: 37904848

Doi: 10.7717/peerj.16306

Products & Services: Recombinant Proteins

A Small RNA, SaaS, Promotes Salmonella Pathogenicity by Regulating Invasion, Intracellular Growth, and Virulence Factors

Authors: Lin-Lin Cai, Yun-Ting Xie , Hai-Jing Hu , Xing-Lian Xu , Hu-Hu Wang , Guang-Hong Zhou

Journal: Microbiol Spectr .

PubMed ID: 36688642

Doi: 10.1128/spectrum.02938-22

Products & Services: Proteins, Expression, Isolation and Analysis

UV-induced G4 DNA structures recruit ZRF1 which prevents UV-induced senescence

Authors: Alessio De Magis, Michaela Limmer, Venkat Mudiyam, David Monchaud, Stefan Juranek, Katrin Paeschke

Journal: Nat Commun

PubMed ID: 37872164

Doi: 10.1038/s41467-023-42494-x

Products & Services: Proteins, Expression, Isolation and Analysis

Requires the Type II Secretion System for Pathogenicity and Survival in Grapevine

Authors: Brian Ingel, Claudia Castro, Lindsey Burbank, Nancy Her, N Itzel De Anda, Hannah Way, Peng Wang, M Caroline Roper

Journal: Mol Plant Microbe Interact

PubMed ID: 37188464

Doi: 10.1094/MPMI-03-23-0027-R

Products & Services: Gene Synthesis

Aggregative adherence fimbriae form compact structures as seen by SAXS

Authors: Rie Jønsson, Alexander Björling, Søren Roi Midtgaard, Grethe Vestergaard Jensen, Nicholas Skar-Gislinge, Lise Arleth, Steve Matthews, Karen Angeliki Krogfelt, Håvard Jenssen

Journal: Sci Rep

PubMed ID: 37783694

Doi: 10.1038/s41598-023-42079-0

Products & Services: Proteins, Expression, Isolation and Analysis

A morpheein equilibrium regulates catalysis in phosphoserine phosphatase SerB2 from Mycobacterium tuberculosis

Authors: Elise Pierson, Florian De Pol, Marianne Fillet, Johan Wouters

Journal: Commun Biol

PubMed ID: 37817000

Doi: 10.1038/s42003-023-05402-z

Products & Services: CRISPR Plasmids

MiR-143-3p/FNDC5 axis: a novel regulator of insulin sensitivity

Authors: Biao Li, Ying Dong, Siyuan Hu, Tiancai Liu

Journal: Endocrine

PubMed ID: 37815745

Doi: 10.1007/s12020-023-03522-4

Products & Services: DNA Sequencing

An in vitro-transcribed circular RNA targets the mitochondrial inner membrane cardiolipin to ablate EIF4G2/PTBP1 pan-adenocarcinoma

Authors: Zunyong Feng, Xuanbo Zhang, Jing Zhou, Qiang Li, Liuxi Chu, Guangfu Di, Zhengyuan Xu, Qun Chen, Ming Wang, Xiaochun Jiang, Hongping Xia, Xiaoyuan Chen

Journal: Nat Cancer

PubMed ID: 37845485

Doi: 10.1038/s43018-023-00650-8

Products & Services: DNA Sequencing

Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae

Authors: Yu-Min Li, Yu-Chao Mei, Ao-Hui Liu, Ru-Xin Wang, Runfa Chen, Hai-Ning Du

Journal: Cell Rep

PubMed ID: 37796660

Doi: 10.1016/j.celrep.2023.113186

Products & Services: Gene Synthesis

Differential modulation of cellular phenotype and drug sensitivity by extracellular matrix proteins in primary and metastatic pancreatic cancer cells

Authors: Olalekan H Usman, Sampath Kumar, Reddick R Walker, Gengqiang Xie, Hyeje C Sumajit, AbdelAziz R Jalil, Subramanian Ramakrishnan, Lawrence J Dooling, Yue Julia Wang, Jerome Irianto

Journal: Mol Biol Cell

PubMed ID: 37903222

Doi: 10.1091/mbc.E23-02-0075

Products & Services: Catalog Peptides

Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases

Authors: Shaojie Cui, Anchal Ghai, Yaqin Deng, Shili Li, Ruihui Zhang, Christopher Egbulefu, Guosheng Liang, Samuel Achilefu, Jin Ye

Journal: Mol Cell

PubMed ID: 37863053

Doi: 10.1016/j.molcel.2023.09.025

Products & Services: Molecular Biology Reagents

Propofol Promoted the Cell Growth and Epithelial Mesenchymal Transformation of the HTR-8/SVneo Cells through Targeting the METTL3 Mediated ZEB2

Authors: Long Cheng, Liang Zhao, Geng Wang

Journal: Reprod Sci

PubMed ID: 37814200

Doi: 10.1007/s43032-023-01368-9

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Recombinant adeno-associated virus production evaluation in Chinese hamster ovary cells

Authors: Thu M Cao, Dayue Chen, Gavin C Barnard, Amy Shen

Journal: Biotechnol Bioeng

PubMed ID: 37902721

Doi: 10.1002/bit.28578

Products & Services: Proteins, Expression, Isolation and Analysis

Structure and function analysis of a type III preQ1-I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence

Authors: Griffin M Schroeder , Daniil Kiliushik , Jermaine L Jenkins , Joseph E Wedekind

Journal: J Biol Chem .

PubMed ID: 37660906

Doi: 10.1016/j.jbc.2023.105208

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A novel C-type lectin (SpccCTL) suppresses MCRV replication by binding viral protein and regulating antiviral peptides in Scylla paramamosain

Authors: Qing-Feng Yang, Shouhu Li, Guang-Peng Feng, Chuang Qin, Xiu-Wen Min, Wen-Hong Fang, Yue Wu, Jin Zhou, Xin-Cang Li

Journal: Fish Shellfish Immunol

PubMed ID: 37827249

Doi: 10.1016/j.fsi.2023.109143

Products & Services: Proteins, Expression, Isolation and Analysis

CRISPR/Cas9 System-Mediated Multi-copy Expression of an Alkaline Serine Protease in for the Production of XOD-Inhibitory Peptides

Authors: Shounan Wang, Yibin Xue, Peng Zhang, Qiaojuan Yan, Yanxiao Li, Zhengqiang Jiang

Journal: J Agric Food Chem

PubMed ID: 37807677

Doi: 10.1021/acs.jafc.3c04138

Products & Services: Proteins, Expression, Isolation and Analysis

Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies

Authors: Matthias Schmidt, Namil Lee, Chunjun Zhan, Jacob B Roberts, Alberto A Nava, Leah S Keiser, Aaron A Vilchez, Yan Chen, Christopher J Petzold, Robert W Haushalter, Lars M Blank, Jay D Keasling

Journal: ACS Synth Biol

PubMed ID: 37851920

Doi: 10.1021/acssynbio.3c00367

Products & Services: Proteins, Expression, Isolation and Analysis

Cornelia de Lange Syndrome mutations in SMC1A cause cohesion defects in yeast

Authors: Jingrong Chen, Erin N Floyd, Dean S Dawson, Susannah Rankin

Journal: Genetics

PubMed ID: 37650609

Doi: 10.1093/genetics/iyad159

Products & Services: Proteins, Expression, Isolation and Analysis

The CD4+ T cell repertoire specific for citrullinated peptides shows evidence of immune tolerance

Authors: Matthew K McElwee, Thamotharampillai Dileepan, Shawn A Mahmud, Marc K Jenkins

Journal: J Exp Med

PubMed ID: 37831103

Doi: 10.1084/jem.20230209

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Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform

Authors: Alexander Ernst, Indre Piragyte, Ayisha Marwa Mp, Ngoc Dung Le, Denis Grandgirard, Stephen L Leib, Andrew Oates, Nadia Mercader

Journal: Sci Rep

PubMed ID: 37813860

Doi: 10.1038/s41598-023-43911-3

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Allele-dependent expression and functionality of lipid enzyme PDAT affects diatom carbon storage and growth

Authors: Yufang Pan, Wanting Zhang, Xiaofei Wang, Juliette Jouhet, Eric Maréchal, Jin Liu, Xiao-Qin Xia, Hanhua Hu

Journal: Plant Physiol

PubMed ID: 37930282

Doi: 10.1093/plphys/kiad581

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Loss of ATG4B and ATG4A results in two-stage cell cycle defects in pancreatic ductal adenocarcinoma cells

Authors: Paalini Sathiyaseelan, Suganthi Chittaranjan, Steve E Kalloger, Jennifer Chan, Nancy E Go, Mario A Jardon, Cally J Ho, Theodore Hui, Jing Xu, Christine Chow, Dongxia Gao, Fraser D Johnson, William W Lockwood, Gregg B Morin, Daniel J Renouf, David F Schaeffer, Sharon M Gorski

Journal: J Cell Sci

PubMed ID: 37701987

Doi: 10.1242/jcs.260644

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The Exocyst Subunit CsExo70B Promotes Both Fruit Length and Disease Resistance via Regulating Receptor Kinase Abundance at Plasma Membrane in Cucumber

Authors: Liu Liu , Jiacai Chen , Chaoheng Gu , Shaoyun Wang , Yufan Xue , Zhongyi Wang , Lijie Han , Weiyuan Song , Xiaofeng Liu , Jiahao Zhang , Min Li , Chuang Li , Liming Wang , Xiaolan Zhang , Zhaoyang Zhou

Journal: Plant Biotechnol J .

PubMed ID: 37795910

Doi: 10.1111/pbi.14189

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A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo

Authors: Eirini Giannakopoulou , Madeleine Lehander , Stina Virding Culleton , Weiwen Yang , Yingqian Li , Terhi Karpanen , Tetsuichi Yoshizato , Even H Rustad , Morten Milek Nielsen , Ravi Chand Bollineni , Trung T Tran , Marina Delic-Sarac , Thea Johanne Gjerdingen , Karolos Douvlataniotis , Maarja Laos , Muhammad Ali , Amy Hillen , Stefania Mazzi , Desmond Wai Loon Chin , Adi Mehta , Jeppe Sejerø Holm , Amalie Kai Bentzen , Marie Bill , Marieke Griffioen , Tobias Gedde-Dahl, Sören Lehmann , Sten Eirik W Jacobsen , Petter S Woll , Johanna Olweus

Journal: Nat Cancer .

PubMed ID: 37783807

Doi: 10.1038/s43018-023-00642-8

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Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2

Authors: Bradly Burke, Savannah M Rocha, Shijun Zhan, Miles Eckley, Clara Reasoner, Amin Addetia, Juliette Lewis, Anna Fagre, Phillida A Charley, Juergen A Richt, Susan R Weiss, Ronald B Tjalkens, David Veesler, Tawfik Aboellail, Tony Schountz

Journal: PLoS Pathog

PubMed ID: 37856551

Doi: 10.1371/journal.ppat.1011728

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Fasciola hepatica antioxidant and protease-inhibitor cocktail recombinant vaccines administered five times elicit potent and sustained immune responses in sheep but do not confer protection

Authors: Krystyna Cwiklinski, Amanda McEvoy, Jesús López Corrales, Heather Jewhurst, Nichola Eliza Davies Calvani, Carolina De Marco Verissimo, Amber Louise Dorey, Orla M Keane, John Pius Dalton, Richard Lalor

Journal: Vet Parasitol

PubMed ID: 37826973

Doi: 10.1016/j.vetpar.2023.110049

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Identification and evaluation in-vitro of conserved peptides with high affinity to MHC-I as potential protective epitopes for Newcastle disease virus vaccines

Authors: Luis Tataje-Lavanda, Edith Málaga, Manuela Verastegui, Egma Mayta Huatuco, Eliana Icochea, Manolo Fernández-Díaz, Mirko Zimic

Journal: BMC Vet Res

PubMed ID: 37805566

Doi: 10.1186/s12917-023-03726-w

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A novel metalloproteinase-derived cryptide from Bothrops cotiara venom inhibits angiotensin-converting enzyme activity

Authors: Jackson Gabriel Miyamoto, Eduardo Shigueo Kitano, André Zelanis, Pedro Gabriel Nachtigall, Inácio Junqueira-de-Azevedo, Sávio Stefanini Sant'Anna, Rogério Lauria da Silva, Patrícia Alessandra Bersanetti, Adriana Karaoglanovic Carmona, Pedro José Barbosa Pereira, Solange M T Serrano, Maria Luiza Vilela Oliva, Alexandre Keiji Tashima

Journal: Biochimie

PubMed ID: 37839625

Doi: 10.1016/j.biochi.2023.10.010

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Sulforaphane alleviates the meiosis defects induced by 3-nitropropionic acid in mouse oocytes

Authors: Wei-Jian Li, Xuan Zhang, Ming Shen, Hong-Lin Liu, Li-Ren Ding

Journal: Food Chem Toxicol

PubMed ID: 37783421

Doi: 10.1016/j.fct.2023.114083

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Discovering human cell-compatible gene therapy virus variants via optimized screening in mouse models

Authors: Moyu Dai, Ning Yang, Kai Xu, Jingwen Zhang, Xueke Li, Ying Zhang, Wei Li

Journal: Cell Prolif

PubMed ID: 37864397

Doi: 10.1111/cpr.13565

Products & Services: Proteins, Expression, Isolation and Analysis

T cells Use Focal Adhesions to Pull Themselves Through Confined Environments

Authors: Alexia Caillier, David Oleksyn, Deborah J Fowell, Jim Miller, Patrick W Oakes

Journal: biorxiv

PubMed ID: 37904911

Doi: 10.1101/2023.10.16.562587

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Development of a counterselectable system for rapid and efficient CRISPR-based genome engineering in Zymomonas mobilis

Authors: Yanli Zheng, Hongmei Fu, Jue Chen, Jie Li, Yuejie Bian, Ping Hu, Lei Lei, Yihan Liu, Jiangke Yang, Wenfang Peng

Journal: Microb Cell Fact

PubMed ID: 37833755

Doi: 10.1186/s12934-023-02217-9

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Rules and mechanisms governing G protein coupling selectivity of GPCRs

Authors: Ikuo Masuho , Ryoji Kise , Pablo Gainza , Ee Von Moo , Xiaona Li , Ryosuke Tany , Hideko Wakasugi-Masuho , Bruno E Correia , Kirill A Martemyanov

Journal: Cell Rep .

PubMed ID: 37742189

Doi: 10.1016/j.celrep.2023.113173

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Evaluation and comparison of immune responses induced by two Mpox mRNA vaccine candidates in mice

Authors: Xidan Yang , Congxia Hu , Xuetao Yang , Xiu Yang , Xing Hu , Xingyun Wang , Cong Liu, Yuan Yuan , Shouwen Du , Peng George Wang, Jihui Lin

Journal: J Med Virol .

PubMed ID: 37800627

Doi: 10.1002/jmv.29140

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Horizontally transferred salivary protein promotes insect feeding by suppressing ferredoxin-mediated plant defenses

Authors: Yi-Zhe Wang , Yu-Xuan Ye , Jia-Bao Lu , Xin Wang , Hai-Bin Lu , Ze-Long Zhang , Zhuang-Xin Ye , Yu-Wen Lu , Zong-Tao Sun , Jian-Ping Chen , Jun-Min Li , Chuan-Xi Zhang , Hai-Jian Huang

Journal: Mol Biol Evol .

PubMed ID: 37804524

Doi: 10.1093/molbev/msad221

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Rapid characterization of anti-CRISPR proteins and optogenetically engineered variants using a versatile plasmid interference system

Authors: Guoxu Song, Chunhong Tian, Jiahui Li, Fei Zhang, Yuxin Peng, Xing Gao and Yong Tian

Journal: Nucleic Acids Research

Doi: 10.1093/nar/gkad995

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Establishment and characterization of a novel indirect ELISA method based on ASFV antigenic epitope-associated recombinant protein

Authors: Jiaxin Jin , Yilin Bai , Yuanyuan Zhang , Wenlong Lu , Shuai Zhang , Xuyang Zhao , Yaning Sun , Yanan Wu , Angke Zhang , Gaiping Zhang , Aijun Sun , Guoqing Zhuang

Journal: Int J Biol Macromol .

PubMed ID: 37865977

Doi: 10.1016/j.ijbiomac.2023.127311

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Structural and functional characterization of Aedes aegypti pupal cuticle protein that controls dengue virus infection

Authors: Qingqing Huang, Edem Gavor, Nikhil Kumar Tulsian, Jingsong Fan, Qingsong Lin, Yu Keung Mok, R Manjunatha Kini, J Sivaraman

Journal: Protein Sci

PubMed ID: 37593853

Doi: 10.1002/pro.4761

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A two-arm analysis of the immune response to heterologous boosting of inactivated SARS-CoV-2 vaccines

Authors: Arnone Nithichanon, Ludthawun Kamuthachad, Kanin Salao, Wisitsak Phoksawat, Chatcharin Kamsom, Surasakdi Wongratanacheewin, Chonlatip Pipattanaboon, Sakawrat Kanthawong, Umaporn Yordpratum, Sirinart Aromseree, Atibordee Meesing, Piroon Mootsikapun, Steven W Edwards, Supranee Phanthanawiboon

Journal: Sci Rep

PubMed ID: 37907584

Doi: 10.1038/s41598-023-46053-8

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The cell-end protein Tea4 spatially regulates hyphal branch initiation and appressorium remodeling in the blast fungus

Authors: Audra Mae Rogers, Rachel Taylor, Martin John Egan

Journal: Mol Biol Cell

PubMed ID: 37903237

Doi: 10.1091/mbc.E23-06-0214

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SARS-CoV-2 infection of human lung epithelial cells induces TMPRSS-mediated acute fibrin deposition

Authors: Rachel Erickson, Chang Huang, Cameron Allen, Joanna Ireland, Gwynne Roth, Zhongcheng Zou, Jinghua Lu, Bernard A P Lafont, Nicole L Garza, Beniah Brumbaugh, Ming Zhao, Motoshi Suzuki, Lisa Olano, Joseph Brzostowski, Elizabeth R Fischer, Homer L Twigg, Reed F Johnson, Peter D Sun

Journal: Nat Commun

PubMed ID: 37821447

Doi: 10.1038/s41467-023-42140-6

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Differential regulation of fibronectin expression and fibrillogenesis by autocrine TGF-β1 signaling in malignant and benign mammary epithelial cells

Authors: Michael M Sofroniou, Christopher A Lemmon

Journal: Int J Biochem Cell Biol

PubMed ID: 37866655

Doi: 10.1016/j.biocel.2023.106478

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Modulating biofilm can potentiate activity of novel plastic-degrading enzymes

Authors: Sophie A Howard, Ronan R McCarthy

Journal: NPJ Biofilms Microbiomes

PubMed ID: 37788986

Doi: 10.1038/s41522-023-00440-1

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Development of CRISPR/Cas9-Based Genome Editing Tools for Polyploid Yeast Cyberlindnera jadinii and Its Application in Engineering Heterologous Steroid-Producing Strains

Authors: Lishan Gu, Rongxin Zhang, Xuqian Fan, Yu Wang, Kaiyu Ma, Jingjing Jiang, Gen Li, Honglei Wang, Feiyu Fan, Xueli Zhang

Journal: ACS Synth Biol

PubMed ID: 37816156

Doi: 10.1021/acssynbio.3c00278

Products & Services: Codon Optimization

MpADC, an L-aspartate-α-decarboxylase, from Myzus persicae, that enables production of β-alanine with high yield by whole-cell enzymatic catalysis

Authors: Pengfu Liu, Saixue Xie, Qian Guo, Yan Chen, Junying Fan, Ashok Kumar Nadda, Xiaoluo Huang, Xiaohe Chu

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 37876019

Doi: 10.1186/s13068-023-02405-0

Products & Services: Proteins, Expression, Isolation and Analysis

Author Correction: Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses

Authors: Xiuyuan Ou, Ge Xu, Pei Li, Yan Liu, Fuwen Zan, Pan Liu, Jiaxin Hu, Xing Lu, Siwen Dong, Yao Zhou, Zhixia Mu, Zhiqiang Wu, Jianwei Wang, Qi Jin, Pinghuang Liu, Jian Lu, Xiangxi Wang, Zhaohui Qian

Journal: Cell Discov

PubMed ID: 37813850

Doi: 10.1038/s41421-023-00597-1

Products & Services: Proteins, Expression, Isolation and Analysis

G-quadruplexes of KSHV oriLyt play important roles in promoting lytic DNA replication

Authors: Prerna Dabral, Timsy Uppal, Subhash C Verma

Journal: Microbiol Spectr

PubMed ID: 37800915

Doi: 10.1128/spectrum.05316-22

Products & Services: Proteins, Expression, Isolation and Analysis

Expression of a SAG protein with a CAP domain from Eimeria necatrix and its role in invasion and immunoprotection

Authors: Feiyan Wang, Amin Zhang, Xuelian Fan, Qianqian Feng, Zhizhi Zhang, Dandan Liu, Shijie Su, Zhaofeng Hou, Jinjun Xu, Xilong Kang, Zhiming Pan, Hunjie Hu, Jianping Tao

Journal: Vet Parasitol

PubMed ID: 37931477

Doi: 10.1016/j.vetpar.2023.110060

Products & Services: Proteins, Expression, Isolation and Analysis

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