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Chimeric Antigen Receptor T Cell Therapy Targeting Epithelial Cell Adhesion Molecule in Gastric Cancer: Mechanisms of Tumor Resistance
Authors: Yanping Yang, Raymond Louie, Janusz Puc, Yogindra Vedvyas, Yago Alcaina, Irene M Min, Matt Britz, Fabio Luciani, Moonsoo M Jin
Journal: Cancers (Basel)
PubMed ID: 38067255
Doi: 10.3390/cancers15235552
Regulation of Atg8 membrane deconjugation by cysteine proteases in the malaria parasite Plasmodium berghei
Authors: Akancha Mishra, Aastha Varshney, Satish Mishra
Journal: Cell Mol Life Sci
PubMed ID: 37910326
Doi: 10.1007/s00018-023-05004-2
Products & Services: Peptide Synthesis   
Enhancing the Physicochemical Attributes of Dough and Noodles through the Incorporation of Laccase
Authors: Xiaoyu Zhu, Shijin Zhang, Luyao Bian, Juan Shen, Chong Zhang, Sivakumar Manickam, Yang Tao, Zhaoxin Lu
Journal: Foods
PubMed ID: 38002203
Doi: 10.3390/foods12224146
Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51
Authors: Lei Tao, Yue Zhou, Xiangyu Pan, Yuan Luo, Jiahao Qiu, Xia Zhou, Zhiqian Chen, Yan Li, Lian Xu, Yang Zhou, Zeping Zuo, Chunqi Liu, Liang Wang, Xiaocong Liu, Xinyu Tian, Na Su, Zhengnan Yang, Yu Zhang, Kun Gou, Na Sang, Huan Liu, Jiao Zou, Yuzhou Xiao, Xi Zhong, Jing Xu, Xinyu Yang, Kai Xiao, Yanyang Liu, Shengyong Yang, Yong Peng, Junhong Han, Xiaobo Cen, Yinglan Zhao
Journal: Nat Commun
PubMed ID: 37973845
Doi: 10.1038/s41467-023-42850-x
Products & Services: Molecular Biology Reagents   
Author Correction: A Rift Valley fever mRNA vaccine elicits strong immune responses in mice and rhesus macaques
Authors: Ting Bian, Meng Hao, Xiaofan Zhao, Chuanyi Zhao, Gang Luo, Zhendong Zhang, Guangcheng Fu, Lu Yang, Yi Chen, Yudong Wang, Changming Yu, Yilong Yang, Jianmin Li, Wei Chen
Journal: npj Vaccines
PubMed ID: 38017028
Doi: 10.1038/s41541-023-00780-1
Inflammation primes the kidney for recovery by activating AZIN1 A-to-I editing
Authors: Segewkal Heruye, Jered Myslinski, Chao Zeng, Amy Zollman, Shinichi Makino, Azuma Nanamatsu, Quoseena Mir, Sarath Chandra Janga, Emma H Doud, Michael T Eadon, Bernhard Maier, Michiaki Hamada, Tuan M Tran, Pierre C Dagher, Takashi Hato
Journal: biorxiv
PubMed ID: 37986799
Doi: 10.1101/2023.11.09.566426
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Dual function of Zika virus NS2B-NS3 protease
Authors: Sergey A Shiryaev, Piotr Cieplak, Anton Cheltsov, Robert C Liddington, Alexey V Terskikh
Journal: PLoS Pathog
PubMed ID: 38011215
Doi: 10.1371/journal.ppat.1011795
Products & Services: Custom RNAi Services   
Engineering the synthetic β-alanine pathway in Komagataella phaffii for conversion of methanol into 3-hydroxypropionic acid
Authors: Sílvia Àvila-Cabré, Míriam Pérez-Trujillo, Joan Albiol, Pau Ferrer
Journal: Microb Cell Fact
PubMed ID: 37978380
Doi: 10.1186/s12934-023-02241-9
Comparison of biliary protein spectrum in gallstone patients with obesity and those with normal body weight
Authors: Min-Zhi Chen, Ping Xie, Xiao-Chang Wu, Zhen-Hua Tan, Hai Qian, Zhi-Hong Ma, Xing Yao
Journal: Hepatobiliary Pancreat Dis Int
PubMed ID: 38040523
Doi: 10.1016/j.hbpd.2023.11.007
Products & Services: Protein Tools   
A Subunit Vaccine Candidate Composed of Mpox Virus A29L, M1R, A35R, and B6R Elicits Robust Immune Response in Mice
Authors: Xuetao Yang , Xidan Yang , Shouwen Du , Congxia Hu , Xiu Yang , Xingyun Wang , Xing Hu , Nino Rcheulishvili , Peng George Wang and Jihui Lin
Journal: Vaccines.
Doi: 10.3390/vaccines11091420
Products & Services: Gene Synthesis   
Fluorescence-quenching lateral flow immunoassay for “turn-on” and sensitive detection of anti-SARS-CoV-2 neutralizing antibodies in human serum
Authors: Lun Bian , Qiangqiang Fu , Zhuoheng Gan , Ze Wu , Yuchen Song , Yufeng Xiong , Fang Hu, Lei Zheng
Journal: Adv Sci (Weinh) .
PubMed ID: 38032112
Doi: 10.1002/advs.202305774
Products & Services: Recombinant Proteins   
Functional Characterization of Novel Variants Identified in Two Unrelated Patients with Morbid Obesity in Qatar
Authors: Idris Mohammed, Senthil Selvaraj, Wesam S Ahmed, Tara Al-Barazenji, Ayat S Hammad, Hajar Dauleh, Luis R Saraiva, Mashael Al-Shafai, Khalid Hussain
Journal: Int J Mol Sci
PubMed ID: 38003551
Doi: 10.3390/ijms242216361
Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors
Authors: Mikhail Rudinskiy, Maria Pons-Vizcarra, Tatiana Soldà, Ilaria Fregno, Timothy Jan Bergmann, Ana Ruano, Aida Delgado, Sara Morales, Xavier Barril, Manolo Bellotto, Elena Cubero, Ana María García-Collazo, Natalia Pérez-Carmona, Maurizio Molinari
Journal: PLoS ONE
PubMed ID: 38019733
Doi: 10.1371/journal.pone.0294437
Galectin-14 promotes hepatocellular carcinoma tumor growth enhancing heparan sulfate proteoglycan modification
Authors: Liming Gou, Gang Yang, Sujuan Ma, Tong Ding, Luan Sun, Fang Liu, Jin Huang, Wei Gao
Journal: J Biomed Res
PubMed ID: 37977559
Doi: 10.7555/JBR.37.20230085
EBF2 Links KMT2D-Mediated H3K4me1 to Suppress Pancreatic Cancer Progression via Upregulating KLLN
Authors: Bing Yao, Mengying Xing, Shixin Meng, Shang Li, Jingwan Zhou, Ming Zhang, Chen Yang, Shuang Qu, Yucui Jin, Hongyan Yuan, Ke Zen, Changyan Ma
Journal: Adv Sci (Weinh)
PubMed ID: 38015024
Doi: 10.1002/advs.202302037
Products & Services: Peptide Synthesis   
A nanoparticle vaccine displaying the ookinete PSOP25 antigen elicits transmission-blocking antibody response against Plasmodium berghei
Authors: Guixiang Yao, Hui Min, Xinxin Yu, Fei Liu, Liwang Cui, Yaming Cao
Journal: Parasit Vectors
PubMed ID: 37932796
Doi: 10.1186/s13071-023-06020-8
Suburban Population of Bobcats (Lynx rufus) in Connecticut, USA, Tested Negative for SARS-CoV-2, November 2021-February 2022
Authors: Maureen Sims, Zeinab Helal, Milton Levin, Tracy Rittenhouse, Jason Hawley, Guillermo R Risatti
Journal: J Wildl Dis
PubMed ID: 37924242
Doi: 10.7589/JWD-D-23-00054
Heterologous booster with a novel formulation containing glycosylated trimeric S protein is effective against Omicron
Authors: Daniela Bottero, Erika Rudi, Pablo Martin Aispuro, Eugenia Zurita, Emilia Gaillard, Maria M Gonzalez Lopez Ledesma, Juan Malito, Matthew Stuible, Nicolas Ambrosis, Yves Durocher, Andrea V Gamarnik, Andrés Wigdorovitz, Daniela Hozbor
Journal: Front Immunol
PubMed ID: 38022542
Doi: 10.3389/fimmu.2023.1271209
Dynamics of Serum-Neutralizing Antibody Responses in Vaccinees through Multiple Doses of the BNT162b2 Vaccine
Authors: Jared Sheehan, Caleb M Ardizzone, Mayank Khanna, Amber J Trauth, Michael E Hagensee, Alistair J Ramsay
Journal: Vaccines (Basel)
PubMed ID: 38006052
Doi: 10.3390/vaccines11111720
Products & Services: Gene Synthesis   
Cytoplasmic production of Fabs in chemically defined media in fed-batch fermentation
Authors: Angel Castillo-Corujo, Mirva J Saaranen, Lloyd W Ruddock
Journal: Protein Expr Purif
PubMed ID: 37979630
Doi: 10.1016/j.pep.2023.106404
Molecular Analysis of a Congenital Myasthenic Syndrome Due to a Pathogenic Variant Affecting the C-Terminus of ColQ
Authors: Susie Barbeau, Fannie Semprez, Alexandre Dobbertin, Laurine Merriadec, Florine Roussange, Bruno Eymard, Damien Sternberg, Emmanuel Fournier, Hanice Karasoy, Cécile Martinat, Claire Legay
Journal: Int J Mol Sci
PubMed ID: 38003406
Doi: 10.3390/ijms242216217
Products & Services: Gene Synthesis   
Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets
Authors: Qing Tang, Sebastian Sensale, Charles Bond, Jiazheng Xing, Andy Qiao, Siewert Hugelier, Arian Arab, Gaurav Arya, Melike Lakadamyali
Journal: Curr Biol
PubMed ID: 37979580
Doi: 10.1016/j.cub.2023.10.068
Products & Services: Monoclonal Antibody Services   
DNA Condensation by Peptide-Conjugated PAMAM Dendrimers Influence of Peptide Charge
Authors: Corinna Dannert, Ingrid Mardal, Rahmi Lale, Bjørn Torger Stokke, Rita S Dias
Journal: ACS Omega
PubMed ID: 38046290
Doi: 10.1021/acsomega.3c05140
Products & Services: Peptide Synthesis   
The HIV-1 capsid serves as a nanoscale reaction vessel for reverse transcription
Authors: Jordan Jennings, Harrison Bracey, Danny T Nguyen, Rishav Dasgupta, Alondra Vázquez Rivera, Nicolas Sluis-Cremer, Jiong Shi, Christopher Aiken
Journal: biorxiv
PubMed ID: 37986899
Doi: 10.1101/2023.11.08.566350
Identification of Protein-Phenol Adducts in Meat Proteins: A Molecular Probe Technology Study
Authors: Fenhong Yang, Yingying Zhu, Xiaohan Li, Fengtao Xiang, Moru Deng, Wei Zhang, Wei Song, Hao Sun, Changbo Tang
Journal: Foods
PubMed ID: 38231694
Doi: 10.3390/foods12234225
Laminin β4 is a constituent of the cutaneous basement membrane zone and additional autoantigen of anti-p200 pemphigoid
Authors: Stephanie Goletz, Manuela Pigors, Tina Rastegar Lari, Christoph M Hammers, Yao Wang, Shirin Emtenani, Monique Aumailley, Maike M Holtsche, Felix H Stang, Imke Weyers, Inke R König, Cristina Has, Christiane Radzimski, Lars Komorowski, Detlef Zillikens, Enno Schmidt
Journal: J Am Acad Dermatol
PubMed ID: 37992812
Doi: 10.1016/j.jaad.2023.11.014
Identification of mouse CD4 T cell epitopes in SARS-CoV-2 BA1 spike and nucleocapsid for use in peptide:MHCII tetramers
Authors: Laura Bricio Moreno, Juliana Barreto de Albuquerque, Jake M Neary, Thao Nguyen, Kathryn M Hastie, Sara Landeras-Bueno, Chitra Hariharan, Anusha Nathan, Matthew A Getz, Alton C Gayton, Ashok Khatri, Gaurav D Gaiha, Erica Ollmann Saphire, Andrew D Luster, James J Moon
Journal: biorxiv
PubMed ID: 38014059
Doi: 10.1101/2023.11.16.566918
Chemical protein synthesis enabled engineering of saccharide oxidative cleavage activity in artificial metalloenzymes
Authors: Jindi Luo, Chunmao He
Journal: Int J Biol Macromol
PubMed ID: 38000595
Doi: 10.1016/j.ijbiomac.2023.128083
Cold atmospheric plasma can effectively disinfect SARS-CoV-2 in the wastewater
Authors: Hongbo Qin, Hengju Qiu, Ke Liu, Bixia Hong, Yuchen Liu, Chun Li, Mengzhe Li, Xiaoping An, Lihua Song, Eric Robert, Yigang Tong, Huahao Fan, Ruixue Wang
Journal: Exploration (Beijing)
PubMed ID: 38939868
Doi: 10.1002/EXP.20230012
Human mesenchymal stem cells derived from adipose tissue showed a more robust effect than those from the umbilical cord in promoting corneal graft survival by suppressing lymphangiogenesis
Authors: Huanmin Kang, Jianing Feng, Yingqian Peng, Yingyi Liu, Yalei Yang, Ying Wu, Jian Huang, Ying Jie, Baihua Chen, Yan He
Journal: Stem Cell Res Ther
PubMed ID: 37957770
Doi: 10.1186/s13287-023-03559-2
Products & Services: Gene Synthesis   
An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant
Authors: Hannah Mende, Anshu Khatri, Carolin Lange, Sergio Alejandro Poveda-Cuevas, Georg Tascher, Adriana Covarrubias-Pinto, Frank Löhr, Sebastian E Koschade, Ivan Dikic, Christian Münch, Anja Bremm, Lorenzo Brunetti, Christian H Brandts, Hannah Uckelmann, Volker Dötsch, Vladimir V Rogov, Ramachandra M Bhaskara, Stefan Müller
Journal: Cell Rep
PubMed ID: 37999976
Doi: 10.1016/j.celrep.2023.113484
Products & Services: Molecular Biology Reagents   
Dual-systems models of the genetic architecture of impulsive personality traits: neurogenetic evidence of distinct but related factors
Authors: Alex P Miller, Ian R Gizer
Journal: Psychol Med
PubMed ID: 38016992
Doi: 10.1017/S0033291723003367
Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway
Authors: Karim H Saba, Valeria Difilippo, Michal Kovac, Louise Cornmark, Linda Magnusson, Jenny Nilsson, Hilda van den Bos, Diana Cj Spierings, Mahtab Bidgoli, Tord Jonson, Vaiyapuri P Sumathi, Otte Brosjö, Johan Staaf, Floris Foijer, Emelie Styring, Michaela Nathrath, Daniel Baumhoer, Karolin H Nord
Journal: J Pathol
PubMed ID: 38010733
Doi: 10.1002/path.6219
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Varying the RGD concentration on a hyaluronic acid hydrogel influences dormancy versus proliferation in brain metastatic breast cancer cells
Authors: Kasra Goodarzi, Rachel Lane, Shreyas S Rao
Journal: J Biomed Mater Res A
PubMed ID: 38018303
Doi: 10.1002/jbm.a.37651
Products & Services: Catalog Peptides   
Retinoid X receptor gamma dictates the activation threshold of group 2 innate lymphoid cells and limits type 2 inflammation in the small intestine
Authors: Yang Zang , Shaorui Liu , Zebing Rao , Yinsheng Wang , Boya Zhang , Hui Li , Yingjiao Cao , Jie Zhou , Zhuxia Shen , Shengzhong Duan , Danyang He , Heping Xu
Journal: Immunity .
PubMed ID: 37714152
Doi: 10.1016/j.immuni.2023.08.019
Products & Services: Catalog Antibody   
Forming a chromium-based interstrand DNA crosslink: Implications for carcinogenicity
Authors: Silas Brown , Sydney Marchi , C Sumner Thomas , Ashlyn R Hale , Molly Lockart , Michael K Bowman , George Christou , Stephen A Woski , John B Vincent
Journal: J Inorg Biochem .
PubMed ID: 38039560
Doi: 10.1016/j.jinorgbio.2023.112439
Products & Services: Custom DNA/RNA Oligos   
Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity
Authors: Le Zheng, Tingting Yang , Hangtian Guo , Chen Qi , Yuchi Lu , Haonan Xiao , Yan Gao , Yue Liu, Yixuan Yang , Mengru Zhou , Henry C Nguyen 1, Yun Zhu 8, Fei Sun 9 10, Chen-Yu Zhang , Xiaoyun Ji
Journal: Cell Research
PubMed ID: 37932445
Doi: s41422-023-00893-1
Products & Services: Codon Optimization   Peptide Synthesis   
Characterization of an L-Arabinose Isomerase from Bacillus velezensis and Its Application for L-Ribulose and L-Ribose Biosynthesis
Authors: Zongren Guo, Liangkun Long, Shaojun Ding
Journal: Appl Biochem Biotechnol
PubMed ID: 32617845
Doi: 10.1007/s12010-020-03380-0
Products & Services: Custom Vector Construction   
O-Linked N-Acetylglucosamine Transferase Regulates Bone Homeostasis Through Alkaline Phosphatase Pathway in Diabetic Periodontitis
Authors: Wei Luo, Lu Sun
Journal: Mol Biotechnol
PubMed ID: 37951846
Doi: 10.1007/s12033-023-00947-0
Transcriptomic analyses reveal proinflammatory activation of human brain microvascular endothelial cells by aging-associated peptide medin and reversal by nanoliposomes
Authors: Yining Zhang, Nina Karamanova, Kaleb T Morrow, Jillian Madine, Seth Truran, Maria Lozoya, Volkmar Weissig, Ming Li, Mehdi Nikkhah, Jin G Park, Raymond Q Migrino
Journal: Sci Rep
PubMed ID: 37914766
Doi: 10.1038/s41598-023-45959-7
A novel stabilization mechanism accommodating genome length variation in evolutionarily related viral capsids
Authors: Jennifer M Podgorski, Joshua Podgorski, Lawrence Abad, Deborah Jacobs-Sera, Krista G Freeman, Colin Brown, Graham Hatfull, Antoni Luque, Simon J White
Journal: biorxiv
PubMed ID: 37961133
Doi: 10.1101/2023.11.03.565530
Evaluating the stability of host-reference gene expression and simultaneously quantifying parasite burden and host immune responses in murine malaria
Authors: Daniel J Browne, Ashton M Kelly, Jamie Brady, Carla Proietti, Yomani D Sarathkumara, David J Pattinson, Denise L Doolan
Journal: Sci Rep
PubMed ID: 38030676
Doi: 10.1038/s41598-023-48066-9
Products & Services: Plasmid DNA Preparation   
Enhanced C-To-T and A-To-G Base Editing in Mitochondrial DNA with Engineered DdCBE and TALED
Authors: Yinghui Wei, Ming Jin, Shuhong Huang, Fangyao Yao, Ningxin Ren, Kun Xu, Shangpu Li, Pengfei Gao, Yingsi Zhou, Yulin Chen, Hui Yang, Wen Li, Chunlong Xu, Meiling Zhang, Xiaolong Wang
Journal: Adv Sci (Weinh)
PubMed ID: 37984866
Doi: 10.1002/advs.202304113
Products & Services: Codon Optimization   
Carvedilol impairs bile acid homeostasis in mice: implication for nonalcoholic steatohepatitis
Authors: Hana Lastuvkova, Zuzana Nova, Milos Hroch, Fatemeh Alaei Faradonbeh, Jolana Schreiberova, Jaroslav Mokry, Hana Faistova, Alzbeta Stefela, Jan Dusek, Otto Kucera, Radomír Hyspler, Ester Dohnalkova, Rachel L Bayer, Petra Hirsova, Petr Pavek, Stanislav Micuda
Journal: Toxicol Sci
PubMed ID: 37632784
Doi: 10.1093/toxsci/kfad088
Products & Services: Molecular Biology Reagents   
Self−Assembling Nanovaccine Fused with Flagellin Enhances Protective Effect against Foot−and−Mouth Disease Virus
Authors: Chenchen Pei , Hu Dong , Zhidong Teng , Sumin Wei , Yun Zhang , Shuanghui Yin , Jianli Tang , Shiqi Sun and Huichen Guo
Journal: Vaccines
Doi: 10.3390/vaccines11111675
Products & Services: Gene Synthesis   
Multiple highly expressed phosphoenolpyruvate carboxylase genes have divergent enzyme kinetic properties in two C4 grasses
Authors: Robert J DiMario, Ashley N Kophs, Anthony J A Apalla, James N Schnable, Asaph B Cousins
Journal: Ann Bot
PubMed ID: 37675505
Doi: 10.1093/aob/mcad116
SUMOylation-triggered ALIX activation modulates extracellular vesicles circTLCD4-RWDD3 to promote lymphatic metastasis of non-small cell lung cancer
Authors: Xiayao Diao, Chao Guo, Hanhao Zheng, Ke Zhao, Yuming Luo, Mingjie An, Yan Lin, Jiancheng Chen, Yuanlong Li, Yuting Li, Xuehan Gao, Jiaqi Zhang, Mengxin Zhou, Wenliang Bai, Lei Liu, Guige Wang, Lanjun Zhang, Xiaotian He, Rusi Zhang, Zhihua Li, Changhao Chen, Shanqing Li
Journal: Signal Transduct Target Ther
PubMed ID: 37925421
Doi: 10.1038/s41392-023-01685-0
Products & Services: Gene Synthesis   
A Novel mechanism of herbicide action through disruption of pyrimidine biosynthesis
Authors: Il-Ho Kang, Ryan P Emptage, Sang-Ic Kim, Steven Gutteridge
Journal: Proc Natl Acad Sci U S A
PubMed ID: 37988466
Doi: 10.1073/pnas.2313197120
Depletion of L-Methionine in Foods with an Engineered Thermophilic Methionine γ-lyase Efficiently Inhibits Tumor Growth
Authors: Yangming Hu, Yan Liu, Jiulin Zhang, Zhijing Zhou, Jiaxue Wang, Hongyang Chen, Meina Huang, Han Hu, Zongjie Dai, Kaizhi Jia
Journal: J Agric Food Chem
PubMed ID: 37909421
Doi: 10.1021/acs.jafc.3c05293
Functional and Extracellular Production and Antitumor Activity of Mouse Alpha Klotho in Model Microalga Chlamydomonas reinhardtii
Authors: Ramazan Çakmak, Ugur Uzuner
Journal: Chem Biodivers
PubMed ID: 37997005
Doi: 10.1002/cbdv.202301255
Products & Services: Molecular Biology Reagents   
Development of a Multispecies Double-Antigen Sandwich ELISA Using N and RBD Proteins to Detect Antibodies against SARS-CoV-2
Authors: Maritza Cordero-Ortiz, Mónica Reséndiz-Sandoval, Freddy Dehesa-Canseco, Mario Solís-Hernández, Jahir Pérez-Sánchez, Carlos Martínez-Borges, Verónica Mata-Haro, Jesús Hernández
Journal: Animals (Basel)
PubMed ID: 38003105
Doi: 10.3390/ani13223487
Products & Services: Molecular Biology Reagents   
The sleep quality- and myopia-linked PDE11A-Y727C variant impacts neural physiology by reducing catalytic activity and altering subcellular compartmentalization of the enzyme
Authors: Irina Sbornova, Emilie van der Sande, Snezana Milosavljevic, Elvis Amurrio, Steven D Burbano, Prosun Das, Helen Do, Janet L Fisher, Porschderek Kargbo, Janvi Patel, Latarsha Porcher, Chris I De Zeeuw, Magda A Meester-Smoor, Beerend H J Winkelman, Caroline C W Klaver, Ana Pocivavsek, Michy P Kelly
Journal: biorxiv
PubMed ID: 38014312
Doi: 10.1101/2023.11.16.567422
Products & Services: Gene Synthesis   
Identification of NAD-RNA species and ADPR-RNA decapping in Archaea
Authors: José Vicente Gomes-Filho, Ruth Breuer, Hector Gabriel Morales-Filloy, Nadiia Pozhydaieva, Andreas Borst, Nicole Paczia, Jörg Soppa, Katharina Höfer, Andres Jäschke, Lennart Randau
Journal: Nat Commun
PubMed ID: 37989750
Doi: 10.1038/s41467-023-43377-x
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Enzymatic β-elimination in natural product O- and C-glycoside deglycosylation
Authors: Johannes Bitter, Martin Pfeiffer, Annika J E Borg, Kirill Kuhlmann, Tea Pavkov-Keller, Pedro A Sánchez-Murcia, Bernd Nidetzky
Journal: Nat Commun
PubMed ID: 37932298
Doi: 10.1038/s41467-023-42750-0
M mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation
Authors: Maria A Schumacher, Raul Salinas, Brady A Travis, Rajiv Ranjan Singh, Nicholas Lent
Journal: Nat Commun
PubMed ID: 37968329
Doi: 10.1038/s41467-023-43243-w
Using for high-yield production of challenging expression targets and for protein deuteration
Authors: Natalia Mojica, Flore Kersten, Mateu Montserrat-Canals, G Robb Huhn, Abelone M Tislevoll, Gabriele Cordara, Ken Teter, Ute Krengel
Journal: biorxiv
PubMed ID: 37961550
Doi: 10.1101/2023.11.03.565449
Products & Services: Molecular Biology Reagents   
Retraction Note: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs
Authors: Mark Yarmarkovich, Quinlen F Marshall, John M Warrington, Rasika Premaratne, Alvin Farrel, David Groff, Wei Li, Moreno di Marco, Erin Runbeck, Hau Truong, Jugmohit S Toor, Sarvind Tripathi, Son Nguyen, Helena Shen, Tiffany Noel, Nicole L Church, Amber Weiner, Nathan Kendsersky, Dan Martinez, Rebecca Weisberg, Molly Christie, Laurence Eisenlohr, Kristopher R Bosse, Dimiter S Dimitrov, Stefan Stevanovic, Nikolaos G Sgourakis, Ben R Kiefel, John M Maris
Journal: Nature
PubMed ID: 37938785
Doi: 10.1038/s41586-023-06731-z
Products & Services: Peptide Synthesis   
Enzymatic degradation of poly(ethylene terephthalate) (PET): Identifying the cause of the hypersensitive enzyme kinetic response to increased PET crystallinity
Authors: Thore Bach Thomsen, Tobias S Radmer, Anne S Meyer
Journal: Enzyme Microb Technol
PubMed ID: 37979402
Doi: 10.1016/j.enzmictec.2023.110353
Products & Services: Codon Optimization   
Enhancement of adeno-associated virus serotype 6 transduction into T cells with cell-penetrating peptides
Authors: Pablo D Moço, Shantoshini Dash, Amine A Kamen
Journal: J Gene Med
PubMed ID: 37957034
Doi: 10.1002/jgm.3627
Products & Services: Catalog Peptides   
Elevating plant immunity by translational regulation of a rice WRKY transcription factor
Authors: Chao Zheng , Jie Zhou , Xiaoya Yuan , Ersong Zheng , Xiuli Liu , Weijun Cui , Chengqi Yan , Yueyan Wu , Wenyuan Ruan , Keke Yi , Jianping Chen , Xuming Wang
Journal: Plant Biotechnol J .
PubMed ID: 37997501
Doi: 10.1111/pbi.14243
The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson's disease
Authors: Lanxia Meng, Congcong Liu, Yiming Li, Guiqin Chen, Min Xiong, Ting Yu, Lina Pan, Xingyu Zhang, Lingyan Zhou, Tao Guo, Xin Yuan, Chaoyang Liu, Zhaohui Zhang, Zhentao Zhang
Journal: Sci Adv
PubMed ID: 37910610
Doi: 10.1126/sciadv.adj1092
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Bovine papular stomatitis virus as a vaccine vector for cattle
Authors: Gustavo Delhon, Sushil Khatiwada, David Doub, Seth Harris, Sabal Chaulagain, Mostafa El-Gaffary, Daniel L Rock
Journal: J Gen Virol
PubMed ID: 37976092
Doi: 10.1099/jgv.0.001914
Identification of CryAB as a target of NUAK kinase activity in Drosophila muscle tissue
Authors: Ziwei Zhao, David Brooks, Yungui Guo, Erika R Geisbrecht
Journal: Genetics
PubMed ID: 37713608
Doi: 10.1093/genetics/iyad167
Products & Services: Molecular Biology Reagents   
Arabidopsis calmodulin-like proteins CML13 and CML14 interact with calmodulin-binding transcriptional activators and function in salinity stress response
Authors: Bryan Hau, Kyle Symonds, Howard Teresinski, Abby Janssen, Liam Duff, Milena Smith, Kirsten Benidickson, William Plaxton, Wayne A Snedden
Journal: Plant Cell Physiol
PubMed ID: 38036467
Doi: 10.1093/pcp/pcad152
Development of a C3 humanized rat as a new model for evaluating novel C3 inhibitors
Authors: Jin Chen, Lingjun Zhang, Maojing Yang, Elizabeth D Hughes, Zach Freeman, Thomas L Saunders, Feng Lin
Journal: J Innate Immun
PubMed ID: 38035563
Doi: 10.1159/000534963
Products & Services: Plasmid DNA Preparation   
FGFR1 expression correlates inversely with the efficacy of single-agent FGFR-specific inhibitors in pancreatic cancer
Authors: Qingxiang Lin, Andrea Serratore, Jonathan Perri, Tista Roy Chaudhuri, Jun Qu, Wen Wee Ma, Eugene Kandel, Robert M Straubinger
Journal: Br J Pharmacol
PubMed ID: 37994108
Doi: 10.1111/bph.16289
Products & Services: Custom Vector Construction   
Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants
Authors: Shudan Tan, Jinghua Zhao, Xue Hu, Yufeng Li, Zihan Wu, Guoliang Lu, Zhaoli Yu, Binhe Du, Yan Liu, Li Li, Yuchen Chen, Ye Li, Yanfeng Yao, Xiaoyu Zhang, Juhong Rao, Ge Gao, Yun Peng, Hang Liu, Zhiming Yuan, Jia Liu, Qianran Wang, Hengrui Hu, Xiaobo Gao, Hui Zhou, Hang Yu, Yingjie Xu, Wei Yu, Lin Feng, Manli Wang, Chao Shan, Jing Lu, Jinzhong Lin
Journal: Sci Bull (Beijing)
PubMed ID: 37993332
Doi: 10.1016/j.scib.2023.11.024
Fungi of the order Mucorales express a "sealing-only" tRNA ligase
Authors: Khondakar Sayef Ahammed, Ambro van Hoof
Journal: biorxiv
PubMed ID: 38014270
Doi: 10.1101/2023.11.16.567474
Products & Services: Molecular Biology Reagents   
Abundant binary promoter switches in lineage-determining transcription factors indicate a digital component of cell fate determination
Authors: Hongchuan Li, Md Ahasanur Rahman, Michael Ruesch, Caprice D Eisele, Erik M Anderson, Paul W Wright, Jennie Cao, Shashikala Ratnayake, Qingrong Chen, Chunhua Yan, Daoud Meerzaman, Roshini S Abraham, Aharon G Freud, Stephen K Anderson
Journal: Cell Rep
PubMed ID: 37976160
Doi: 10.1016/j.celrep.2023.113454
Products & Services: Codon Optimization   
Circulating extracellular choline acetyltransferase regulates inflammation
Authors: Arielle H Gabalski, Aisling Tynan, Tea Tsaava, Jian Hua Li, Diana Lee, Tyler D Hepler, Daniel Hide, Sam George, Carlos E Bravo Iñiguez, Dane A Thompson, Cassie Zhu, Haichao Wang, Michael Brines, Kevin J Tracey, Sangeeta S Chavan
Journal: J Intern Med
PubMed ID: 38011942
Doi: 10.1111/joim.13750
Products & Services: Catalog Antibody   
Specifications of qPCR based epigenetic immune cell quantification
Authors: Konstantin Schildknecht, Björn Samans, Jasmin Gussmann, Udo Baron, Eva Raschke, Nina Babel, Julia Oppatt, Katharina Gellhaus, Araceli Rossello, Isabell Janack, Sven Olek
Journal: Clin Chem Lab Med
PubMed ID: 37982750
Doi: 10.1515/cclm-2023-1056
Products & Services: Molecular Biology Reagents   
Peptide Amphiphiles as Biodegradable Adjuvants for Efficient Retroviral Gene Delivery
Authors: Kübra Kaygisiz, Lena Rauch-Wirth, Aysenur Iscen, Jan Hartenfels, Kurt Kremer, Jan Münch, Christopher V Synatschke, Tanja Weil
Journal: Adv Healthc Mater
PubMed ID: 37947246
Doi: 10.1002/adhm.202301364
Products & Services: Gene Synthesis   
Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy
Authors: Ali Ghasemi, Amaia Martinez-Usatorre, Luqing Li, Mehdi Hicham, Alan Guichard, Rachel Marcone, Nadine Fournier, Bruno Torchia, Darel Martinez Bedoya, Suzel Davanture, Mirian Fernández-Vaquero, Chaofan Fan, Jakob Janzen, Yahya Mohammadzadeh, Raphael Genolet, Nahal Mansouri, Mathias Wenes, Denis Migliorini, Mathias Heikenwalder, Michele De Palma
Journal: Nat Cancer
PubMed ID: 37996514
Doi: 10.1038/s43018-023-00668-y
Products & Services: PCR Cloning and Subcloning   
Oxidative stress and signaling through EGFR and PKA pathways converge on the nuclear transport factor RanBP1
Authors: Mohamed Kodiha, Nabila Azad, Siwei Chu, Noah Crampton, Ursula Stochaj
Journal: Eur J Cell Biol
PubMed ID: 38011756
Doi: 10.1016/j.ejcb.2023.151376
Products & Services: Codon Optimization   
Nanopore Signatures of Nucleoside Drugs
Authors: Wendong Jia , Yusheng Ouyang , Shanyu Zhang , Xiaoyu Du , Panke Zhang , Shuo Huang
Journal: Nano Lett .
PubMed ID: 37818841
Doi: 10.1021/acs.nanolett.3c02872
Products & Services: Plasmid DNA Preparation   
A chlorophyll c synthase widely co-opted by phytoplankton
Authors: Yanyou Jiang , Tianjun Cao , Yuqing Yang , Huan Zhang , Jingyu Zhang , Xiaobo Li
Journal: Science .
PubMed ID: 37797009
Doi: 10.1126/science.adg7921
Products & Services: Gene Synthesis   
HDL mimetics protect Alzheimer’s patients carrying APOE ε4 from SARS-CoV-2 invasion
Authors: Ruodan Xu , Junwei Gao , Can Cao , Mingfei Shi , Yonghui Zhang , Shihao Hong , Shijie Guo , Menglin Chen , Ping Song , Gaoshuang Fu , Jing Li , Tengxiao Liang , Yingchun Miao , Lu Tang , Jinsheng Yang , Ning Li , Mingdong Dong
Journal: Nano Today
Doi: 10.1016/j.nantod.2023.102051
Products & Services: Gene Synthesis   Peptide Synthesis   
Development and characterization of anti-IL-5 monoclonal antibody Fab fragment for blocking IL-5/IL-5Rα binding
Authors: Shijie Li , Shijie Wang , Eric Fordjour , Yaoji Liang , Xuelian Wang , Yonghao Ye , Zhonghu Bai , Yankun Yang , Yongqi Chen
Journal: International Immunopharmacology
Doi: 10.1016/j.intimp.2023.111032
Products & Services: Gene Synthesis   Peptide Synthesis   
Architecture and rearrangements of a sperm-specific Na/H exchanger
Authors: Sandipan Chowdhury, Kamalendu Pal
Journal: Res Sq
PubMed ID: 37886505
Doi: 10.21203/rs.3.rs-3396005/v1
Extract2Chip-Bypassing Protein Purification in Drug Discovery Using Surface Plasmon Resonance
Authors: Ana C F Paiva, Ana R Lemos, Philipp Busse, Madalena T Martins, Diana O Silva, Micael C Freitas, Sandra P Santos, Filipe Freire, Evelyne J Barrey, Xavier Manival, Lisa Koetzner, Timo Heinrich, Ansgar Wegener, Ulrich Grädler, Tiago M Bandeiras, Daniel Schwarz, Pedro M F Sousa
Journal: Biosensors (Basel)
PubMed ID: 37887106
Doi: 10.3390/bios13100913
Collagen Mimetic Peptide with a Coiled Coil Trimerization Domain Forms Fibrils Having -Period-like Structures
Authors: Faizunnahar Dewan, Michele Kirchner, Fadi Masoud, Zainab Sami, Yujia Xu
Journal: Biomacromolecules
PubMed ID: 37788665
Doi: 10.1021/acs.biomac.3c00901
Products & Services: Molecular Biology Reagents   
Pyruvate kinase is post-translationally regulated by sirtuin 2 in Aedes aegypti mosquitoes
Authors: Natthida Petchampai, Jun Isoe, Prashanth Balaraman, Max Oscherwitz, Brendan H Carter, Cecilia G Sánchez, Patricia Y Scaraffia
Journal: Insect Biochem Mol Biol
PubMed ID: 37797713
Doi: 10.1016/j.ibmb.2023.104015
Products & Services: Molecular Biology Reagents   
Influence of expression and purification protocols on Gα biochemical activity: kinetics of plant and mammalian G protein cycles
Authors: Timothy E Gookin, David Chakravorty, Sarah M Assmann
Journal: biorxiv
PubMed ID: 37214830
Doi: 10.1101/2023.05.10.540258
Products & Services: Molecular Biology Reagents   
Ceria Nanozyme Coordination with Curcumin for Treatment of Sepsis-induced Cardiac Injury by Inhibiting Ferroptosis and Inflammation
Authors: Chenxiao Jiang, Qianzhi Shi, Jing Yang, Hao Ren, Lu Zhang, Shan Chen, Jiayi Si, Yihai Liu, Dujuan Sha, Biao Xu, Jie Ni
Journal: J Adv Res
PubMed ID: 37871772
Doi: 10.1016/j.jare.2023.10.011
Products & Services: PCR Cloning and Subcloning   
Biochemical and structural characterization of a glucan synthase GFGLS2 from edible fungus Grifola frondosa to synthesize β-1, 3-glucan
Authors: Yu-Meng Yang, Xin Fu, Feng-Jie Cui, Lei Sun, Xin-Yi Zan, Wen-Jing Sun
Journal: Biotechnol Biofuels Bioprod
PubMed ID: 37904199
Doi: 10.1186/s13068-023-02380-6
Products & Services: Codon Optimization   
A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity
Authors: Andras Boeszoermenyi, Léa Bernaleau, Xudong Chen, Felix Kartnig, Min Xie, Haobo Zhang, Sensen Zhang, Maeva Delacrétaz, Anna Koren, Ann-Katrin Hopp, Vojtech Dvorak, Stefan Kubicek, Daniel Aletaha, Maojun Yang, Manuele Rebsamen, Leonhard X Heinz, Giulio Superti-Furga
Journal: Nat Commun
PubMed ID: 37863876
Doi: 10.1038/s41467-023-42070-3
Products & Services: Plasmid DNA Preparation   
Serpin-1a and serpin-6 regulate the Toll pathway immune homeostasis by synergistically inhibiting the Spätzle-processing enzyme CLIP2 in silkworm, Bombyx mori
Authors: Huawei Liu, Jiahui Xu, Luoling Wang, Pengchao Guo, Zhangchen Tang, Xiaotong Sun, Xin Tang, Wei Wang, Lingyan Wang, Yang Cao, Qingyou Xia, Ping Zhao
Journal: PLoS Pathog
PubMed ID: 37851691
Doi: 10.1371/journal.ppat.1011740
Products & Services: Peptide Synthesis   
KRAS G12V neoantigen specific T cell receptor for adoptive T cell therapy against tumors
Authors: Dan Lu, Yuan Chen, Min Jiang, Jie Wang, Yiting Li, Keke Ma, Wenqiao Sun, Xing Zheng, Jianxun Qi, Wenjing Jin, Yu Chen, Yan Chai, Catherine W H Zhang, Hao Liang, Shuguang Tan, George F Gao
Journal: Nat Commun
PubMed ID: 37828002
Doi: 10.1038/s41467-023-42010-1
Products & Services: Peptide Synthesis   
Distribution and Degradation of Pork Filamin during Postmortem Aging
Authors: Tongyao Du, Chao Ma, Zixu Wang, Yuejing Hao, Wangang Zhang
Journal: J Agric Food Chem
PubMed ID: 37788342
Doi: 10.1021/acs.jafc.3c04208
Benzbromarone Induces Targeted Degradation of HSP47 Protein and Improves Hypertrophic Scar Formation
Authors: Jung Gyu Park, Dong Chul Lim, Jeong Hwan Park, Seoah Park, Jongsoo Mok, Keon Wook Kang, Joonghoon Park
Journal: J Invest Dermatol
PubMed ID: 37838329
Doi: 10.1016/j.jid.2023.09.279
Products & Services: Recombinant Proteins   
Molecular mechanism of sex pheromone perception in male Mythimna loreyi revealed by in vitro system
Authors: Yun-Ying Zhang, Teng-Fei Bai, Jin-Meng Guo, Zhi-Qiang Wei, Si-Ruo Liu, Yu He, Jing-Jing Ye, Qi Yan, Jin Zhang, Shuang-Lin Dong
Journal: Pest Manag Sci
PubMed ID: 37779104
Doi: 10.1002/ps.7806
Products & Services: Recombinant Proteins   
How myosin VI traps its off-state, is activated and dimerizes
Authors: Louise Canon , Carlos Kikuti , Vicente J Planelles-Herrero , Tianming Lin , Franck Mayeux , Helena Sirkia , Young Il Lee , Leila Heidsieck , Léonid Velikovsky , Amandine David , Xiaoyan Liu , Dihia Moussaoui , Emma Forest , Peter Höök , Karl J Petersen , Tomos E Morgan , Aurélie Di Cicco , Julia Sirés-Campos , Emmanuel Derivery , Daniel Lévy , Cédric Delevoye , H Lee Sweeney , Anne Houdusse
Journal: Nat Commun
PubMed ID: 37872146
Doi: 10.1038/s41467-023-42376-2
Products & Services: PCR Cloning and Subcloning   
m6A methyltransferase METTL3 contributes to sympathetic hyperactivity post-MI via promoting TRAF6-dependent mitochondrial ROS production
Authors: Peijin Yang, Yu Wang, Weili Ge, Yanyan Jing, Hesheng Hu, Jie Yin, Mei Xue, Ye Wang, Xiaolu Li, Xinran Li, Yugen Shi, Jiayu Tan, Yan Li, Suhua Yan
Journal: Free Radic Biol Med
PubMed ID: 37898386
Doi: 10.1016/j.freeradbiomed.2023.10.392
Single-cell chromatin state transitions during epigenetic memory formation
Authors: Taihei Fujimori, Carolina Rios-Martinez, Abby R Thurm, Michaela M Hinks, Benjamin R Doughty, Joydeb Sinha, Derek Le, Antonina Hafner, William J Greenleaf, Alistair N Boettiger, Lacramioara Bintu
Journal: biorxiv
PubMed ID: 37873344
Doi: 10.1101/2023.10.03.560616
Entropy-driven reactions for controlling CRISPR/Cas12a and constructing an electrochemical biosensor for cardiac biomarkers detection
Authors: Jiaying Wang, Xianliang Wang, Bin Li, Kai Zhang, Jingyuan Mao
Journal: Mikrochim Acta
PubMed ID: 37845542
Doi: 10.1007/s00604-023-06012-6
A retrospective study of SARS-CoV-2 seroprevalence in dogs and cats in the Community of Madrid, Spain
Authors: Lidia Sánchez-Morales, José M Sánchez-Vizcaíno, Lucas Domínguez, Sandra Barroso-Arévalo
Journal: Front Microbiol
PubMed ID: 37869682
Doi: 10.3389/fmicb.2023.1264172
Functional dissection and assembly of a small, newly evolved, W chromosome-specific genomic region of the African clawed frog Xenopus laevis
Authors: Caroline M S Cauret, Danielle C Jordan, Lindsey M Kukoly, Sarah R Burton, Emmanuela U Anele, Jacek M Kwiecien, Marie-Theres Gansauge, Sinthu Senthillmohan, Eli Greenbaum, Matthias Meyer, Marko E Horb, Ben J Evans
Journal: PLoS Genet
PubMed ID: 37792893
Doi: 10.1371/journal.pgen.1010990
A dry powder formulation for peripheral lung delivery and absorption of an anti-SARS-CoV-2 ACE2 decoy polypeptide
Authors: Stefania Glieca, Davide Cavazzini, Elisabetta Levati, Valentina Garrapa, Angelo Bolchi, Valentina Franceschi, Simone Odau, Simone Ottonello, Gaetano Donofrio, Jonas Füner, Fabio Sonvico, Ruggero Bettini, Barbara Montanini, Francesca Buttini
Journal: Eur J Pharm Sci
PubMed ID: 37838239
Doi: 10.1016/j.ejps.2023.106609
Creating Designer Engineered Extracellular Vesicles for Diverse Ligand Display, Target Recognition, and Controlled Protein Loading and Delivery
Authors: Alena Ivanova, Lukas Badertscher, Gwen O'Driscoll, Joakim Bergman, Euan Gordon, Anders Gunnarsson, Camilla Johansson, Michael J Munson, Cristiana Spinelli, Sara Torstensson, Liisa Vilén, Andrei Voirel, John Wiseman, Janusz Rak, Niek Dekker, Elisa Lázaro-Ibáñez
Journal: Adv Sci (Weinh)
PubMed ID: 37867228
Doi: 10.1002/advs.202304389
Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors
Authors: Xiuxiu Zhu, Jun Chen, Wuling Li, Yanmin Xu, Juanjuan Shan, Juan Hong, Yongchun Zhao, Huailong Xu, Jiabing Ma, Junjie Shen, Cheng Qian
Journal: Cancer Res
PubMed ID: 37874330
Doi: 10.1158/0008-5472.CAN-23-1038
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