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Application of machine learning algorithms to construct and validate a prediction model for coronary heart disease risk in patients with periodontitis: a population-based study
Authors: Yicheng Wang, Binghang Ni, Yuan Xiao, Yichang Lin, Yu Jiang, Yan Zhang
Journal: Front Cardiovasc Med
PubMed ID: 38094122
Doi: 10.3389/fcvm.2023.1296405
Mutations in yeast Pcf11, a conserved protein essential for mRNA 3' end processing and transcription termination, elicit the Environmental Stress Response
Authors: Joel H Graber, Derick Hoskinson, Huiyun Liu, Katarzyna Kaczmarek Michaels, Peter S Benson, Nathaniel J Maki, Christian L Wilson, Caleb McGrath, Franco Puleo, Erika Pearson, Jason N Kuehner, Claire Moore
Journal: Genetics
PubMed ID: 37967370
Doi: 10.1093/genetics/iyad199
Reduction of oligomer size modulates the competition between cluster formation and phase separation of the tumor suppressor SPOP
Authors: Nafiseh Sabri, Matthew J Cuneo, Melissa R Marzahn, Jihun Lee, Jill J Bouchard, Ömer Güllülü, Sivaraja Vaithiyalingam, Madeleine B Borgia, Jeremy Schmit, Tanja Mittag
Journal: J Biol Chem
PubMed ID: 37926283
Doi: 10.1016/j.jbc.2023.105427
SARS-CoV-2 ORF7a blocked autophagy flux by intervening in the fusion between autophagosome and lysosome to promote viral infection and pathogenesis
Authors: Shun Li, Xiaobo Li, Haowei Liang, Kuike Yu, Jingbo Zhai, Mengzhou Xue, Zhuojing Luo, Chunfu Zheng, Hao Zhang
Journal: J Med Virol
PubMed ID: 37916857
Doi: 10.1002/jmv.29200
RING-type E3 ligase BnaJUL1 ubiquitinates and degrades BnaTBCC1 to regulate drought tolerance in Brassica napus L
Authors: Jin Hu, Mudan Luo, Xianming Zhou, Zhaoyang Wang, Li Yan, Dengfeng Hong, Guangsheng Yang, Xiaohui Zhang
Journal: Plant Cell Environ
PubMed ID: 37984059
Doi: 10.1111/pce.14770
TRIM22 facilitates autophagosome-lysosome fusion by mediating the association of GABARAPs and PLEKHM1
Authors: Hansol Heo, Hyungsun Park, Myung Shin Lee, Jongyoon Kim, Juyeong Kim, Soon-Young Jung, Sun Kyeon Kim, Seongju Lee, Jaerak Chang
Journal: Autophagy
PubMed ID: 38009729
Doi: 10.1080/15548627.2023.2287925
Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans
Authors: Alexandra V Vylegzhanina, Ivan A Bespalov, Ksenia A Novototskaya-Vlasova, Brandon M Hall, Anatoli S Gleiberman, Han Yu, Olga V Leontieva, Katerina I Leonova, Oleg V Kurnasov, Andrei L Osterman, Grace K Dy, Alexey A Komissarov, Elena Vasilieva, Jeff Gehlhausen, Akiko Iwasaki, Christine B Ambrosone, Takemasa Tsuji, Junko Matsuzaki, Kunle Odunsi, Ekaterina L Andrianova, Andrei V Gudkov
Journal: Cancer Res Commun
PubMed ID: 37870410
Doi: 10.1158/2767-9764.CRC-23-0289
Increasing insight in the value of repetitive COVID-19 vaccination in patients with haematological malignancies in the Omicron era
Authors: Ulrike Bacher, Evgenii Shumilov, Thomas Pabst
Journal: Br J Haematol
PubMed ID: 37984996
Doi: 10.1111/bjh.19221
OsALB3 Is Required for Chloroplast Development by Promoting the Accumulation of Light-Harvesting Chlorophyll-Binding Proteins in Rice
Authors: Chao Zhang, Xinchen Mao, Xiaoxiao Feng, Yali Sun, Zirui Wang, Jiaqi Tang, Hengxiu Yu
Journal: Plants (Basel)
PubMed ID: 38068638
Doi: 10.3390/plants12234003
Products & Services: Molecular Biology Reagents   
Structure and functional divergence of PIP peptide family revealed by functional studies on PIP1 and PIP2 in
Authors: Xiao-Song Yu, Hong-Run Wang, Fei-Fan Lei, Rui-Qi Li, Hui-Peng Yao, Jin-Bo Shen, Noor-Ul Ain, Yi Cai
Journal: Front Plant Sci
PubMed ID: 38078092
Doi: 10.3389/fpls.2023.1208549
Products & Services: Peptide Synthesis   
Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia
Authors: Gianna M Branella, Jasmine Y Lee, Jennifer Okalova, Kiran K Parwani, Jordan S Alexander, Raquel F Arthuzo, Andrew Fedanov, Bing Yu, David McCarty, Harrison C Brown, Shanmuganathan Chandrakasan, Brian G Petrich, Christopher B Doering, H Trent Spencer
Journal: Front Immunol
PubMed ID: 38022523
Doi: 10.3389/fimmu.2023.1294555
Products & Services: Combinatorial DNA Libraries   
Substance P Increases STAT6-Mediated Transcription Activation of Lymphocyte Cytosolic Protein 2 to Sustain M2 Macrophage Predominance in Pediatric Asthma
Authors: Miao Li, Xiao Zhong, Wenting Xu
Journal: Am J Pathol
PubMed ID: 37995836
Doi: 10.1016/j.ajpath.2023.11.003
Products & Services: Catalog Antibody   
Juvenile hormone induces reproduction via miR-1175-3p in the red imported fire ant, Solenopsis invicta
Authors: Jie Chen, Ziying Guan, Yunjie Ma, Qingxing Shi, Ting Chen, Muhammad Irfan Waris, Lihua Lyu, Yongyue Lu, Guojun Qi
Journal: Insect Sci
PubMed ID: 37933419
Doi: 10.1111/1744-7917.13291
Products & Services: Catalog Antibody   
Biophysical and biochemical characterization of the thioredoxin system from Colwellia psychrerythraea
Authors: Naheda Sahtout, David A R Sanders
Journal: Proteins
PubMed ID: 37909486
Doi: 10.1002/prot.26627
Products & Services: Molecular Biology Reagents   
Mesenchymal stem cells attenuate systemic lupus erythematosus by inhibiting NLRP3 inflammasome activation through Pim-1 kinase
Authors: Honghong Yu, Qi Li, Huimin Zhu, Chang Liu, Weiwei Chen, Lingyun Sun
Journal: Int Immunopharmacol
PubMed ID: 37992447
Doi: 10.1016/j.intimp.2023.111256
Products & Services: Gene Synthesis   
Human leukocyte antigen HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis
Authors: Joseph R Rouse, Rebecca Danner, Amanda Wahhab, Michaela Pereckas, Mecaila E McClune, Allen C Steere, Klemen Strle, Brandon L Jutras, Robert B Lochhead
Journal: biorxiv
PubMed ID: 38045407
Doi: 10.1101/2023.11.21.568066
Products & Services: Peptide Synthesis   
NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis
Authors: Yves Dondelinger, Dario Priem, Jon Huyghe, Tom Delanghe, Peter Vandenabeele, Mathieu J M Bertrand
Journal: Cell Death Dis
PubMed ID: 37980412
Doi: 10.1038/s41419-023-06284-z
Products & Services: Molecular Biology Reagents   
Single-injection subunit vaccine for rabies prevention using lentinan as adjuvant
Authors: Xiaoyong Zhou, Haozheng Wang, Jianchen Zhang, Ying Guan, Yongjun Zhang
Journal: Int J Biol Macromol
PubMed ID: 37977452
Doi: 10.1016/j.ijbiomac.2023.128118
Telomerase Upregulation Induces Progression of Mouse BrafV600E-Driven Thyroid Cancers and Triggers Nontelomeric Effects
Authors: Iñigo Landa, Caitlin E M Thornton, Bin Xu, Jacob Haase, Gnana P Krishnamoorthy, Jingzhu Hao, Jeffrey A Knauf, Zachary T Herbert, Paula Martínez, María A Blasco, Ronald Ghossein, James A Fagin
Journal: Mol Cancer Res
PubMed ID: 37478162
Doi: 10.1158/1541-7786.MCR-23-0144
Products & Services: PCR Cloning and Subcloning   
A glutamate-gated chloride channel as the mite-specific target-site of dicofol and other diphenylcarbinol acaricides
Authors: Marilou Vandenhole, Catherine Mermans, Berdien De Beer, Wenxin Xue, Yilan Zhao, Yoshihisa Ozoe, Genyan Liu, Wannes Dermauw, Thomas Van Leeuwen
Journal: Commun Biol
PubMed ID: 37957415
Doi: 10.1038/s42003-023-05488-5
Products & Services: Codon Optimization   
Conserved antigen structures and antibody-driven variations on foot-and-mouth disease virus serotype A revealed by bovine neutralizing monoclonal antibodies
Authors: Kun Li, Yong He, Li Wang, Pinghua Li, Huifang Bao, Shulun Huang, Shasha Zhou, Guoqiang Zhu, Yali Song, Ying Li, Sheng Wang, Qianliang Zhang, Pu Sun, Xingwen Bai, Zhixun Zhao, Zhiyong Lou, Yimei Cao, Zengjun Lu, Zaixin Liu
Journal: PLoS Pathog
PubMed ID: 37983290
Doi: 10.1371/journal.ppat.1011811
Sulforaphene suppressed cell proliferation and promoted apoptosis of COV362 cells in endometrioid ovarian cancer
Authors: Hui-Yan Yu, Li Yang, Yuan-Cai Liu, Ai-Jun Yu
Journal: PeerJ
PubMed ID: 38025760
Doi: 10.7717/peerj.16308
Products & Services: Gene Synthesis   
Extracellular and intracellular destruction of Pseudomonas aeruginosa by Dictyostelium discoideum phagocytes mobilize different antibacterial mechanisms
Authors: Imen Ayadi, Otmane Lamrabet, Raphael Munoz-Ruiz, Tania Jauslin, Cyril Guilhen, Pierre Cosson
Journal: Mol Microbiol
PubMed ID: 38017607
Doi: 10.1111/mmi.15197
Isolation and characterization of the aspartame-degrading strain Pseudarthrobacter sp AS-1
Authors: Zhijian Ke, Junyun Song, Jingrui Ma, Mengting Wang, Haiguang Mao, Chunli Xia, Lili Qi, Yidong Zhou, Jinbo Wang
Journal: Environ Pollut
PubMed ID: 37944888
Doi: 10.1016/j.envpol.2023.122883
Products & Services: Gene Synthesis   
Prenatal diagnostic approaches diagnosed craniosynostosis and identified a novel nonsense variant in SMAD6 in a Chinese fetus
Authors: Zhidan Hong, Xuanyi He, Jie Duan, Fang Yu, Huanyu Liu, Dan Lu, Mei Wang, Yuanzhen Zhang
Journal: Gene
PubMed ID: 37977316
Doi: 10.1016/j.gene.2023.147994
Products & Services: Molecular Biology Reagents   
A second-generation M1-polarized CAR macrophage with antitumor efficacy
Authors: Anhua Lei, Hua Yu, Shan Lu, Hengxing Lu, Xizhong Ding, Tianyu Tan, Hailing Zhang, Mengmeng Zhu, Lin Tian, Xudong Wang, Siyu Su, Dixuan Xue, Shaolong Zhang, Wei Zhao, Yuge Chen, Wanrun Xie, Li Zhang, Yuqing Zhu, Jing Zhao, Wenhong Jiang, George Church, Francis Ka-Ming Chan, Zhihua Gao, Jin Zhang
Journal: Nat Immunol
PubMed ID: 38012418
Doi: 10.1038/s41590-023-01687-8
Products & Services: Molecular Biology Reagents   
Role and mechanism of miR-871-3p/Megf8 in regulating formaldehyde-induced cardiomyocyte inflammation and congenital heart disease
Authors: Xiaoli Yuan, Rui Chen, Gang Luo, Pin Sun, Xiaoxia Song, Jianmin Ma, Ruicong Sun, Tao Yu, Zhirong Jiang
Journal: Int Immunopharmacol
PubMed ID: 38039718
Doi: 10.1016/j.intimp.2023.111297
Engineered immunogens to elicit antibodies against conserved coronavirus epitopes
Authors: A Brenda Kapingidza, Daniel J Marston, Caitlin Harris, Daniel Wrapp, Kaitlyn Winters, Dieter Mielke, Lu Xiaozhi, Qi Yin, Andrew Foulger, Rob Parks, Maggie Barr, Amanda Newman, Alexandra Schäfer, Amanda Eaton, Justine Mae Flores, Austin Harner, Nicholas J Catanzaro, Michael L Mallory, Melissa D Mattocks, Christopher Beverly, Brianna Rhodes, Katayoun Mansouri, Elizabeth Van Itallie, Pranay Vure, Brooke Dunn, Taylor Keyes, Sherry Stanfield-Oakley, Christopher W Woods, Elizabeth A Petzold, Emmanuel B Walter, Kevin Wiehe, Robert J Edwards, David C Montefiori, Guido Ferrari, Ralph Baric, Derek W Cain, Kevin O Saunders, Barton F Haynes, Mihai L Azoitei
Journal: Nat Commun
PubMed ID: 38036525
Doi: 10.1038/s41467-023-43638-9
Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity
Authors: Seounghun Kang, Aslan Mansurov, Trevin Kurtanich, Hye Rin Chun, Anna J Slezak, Lisa R Volpatti, Kevin Chang, Thomas Wang, Aaron T Alpar, Kirsten C Refvik, O Isabella Hansen, Gustavo J Borjas, Ha-Na Shim, Kevin T Hultgren, Suzana Gomes, Ani Solanki, Jun Ishihara, Melody A Swartz, Jeffrey A Hubbell
Journal: Sci Adv
PubMed ID: 38019919
Doi: 10.1126/sciadv.adh9879
Jianpi Huayu Decoction suppresses cellular senescence in colorectal cancer via p53-p21-Rb pathway: Network pharmacology and in vivo validation
Authors: Shiting Wang, Ying Xing, Ruiping Wang, Zhichao Jin
Journal: J Ethnopharmacol
PubMed ID: 37931831
Doi: 10.1016/j.jep.2023.117347
Products & Services: Molecular Biology Reagents   
Structure-activity studies of Streptococcus pyogenes enzyme SpyCEP reveal high affinity for CXCL8 in the SpyCEP C-terminal
Authors: Max Pearson, Carl Haslam, Andrew Fosberry, Emma J Jones, Mark Reglinski, Lucy Reeves, Robert J Edwards, Richard Ashley Lawrenson, Jonathan C Brown, Danuta Mossakowska, James Edward Pease, Shiranee Sriskandan
Journal: Sci Rep
PubMed ID: 37923786
Doi: 10.1038/s41598-023-46036-9
Products & Services: Molecular Biology Reagents   
Safety and efficacy of the intranasal spray SARS-CoV-2 vaccine dNS1-RBD: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
Authors: Fengcai Zhu, Shoujie Huang, Xiaohui Liu, Qi Chen, Chunlan Zhuang, Hui Zhao, Jinle Han, Anjuli May Jaen, Thai Hung Do, Jonathan Grant Peter, Alexander Gonzalez Dorado, Louie S Tirador, Gelza Mae A Zabat, Ralph Elvi M Villalobos, Gemalyn Pineda Gueco, Lauren Livia Greta Botha, Shirley Patricia Iglesias Pertuz, Jiaxiang Tan, Kongxin Zhu, Jiali Quan, Hongyan Lin, Yue Huang, Jizong Jia, Xiafei Chu, Junyu Chen, Yixin Chen, Tianying Zhang, Yingying Su, Changgui Li, Xiangzhong Ye, Ting Wu, Jun Zhang, Ningshao Xia
Journal: Lancet Respir Med
PubMed ID: 37979588
Doi: 10.1016/S2213-2600(23)00349-1
Products & Services: Molecular Biology Reagents   
Experimental co-infection of calves with SARS-CoV-2 Delta and Omicron variants of concern
Authors: Konner Cool, Natasha N Gaudreault, Jessie D Trujillo, Igor Morozov, Chester D McDowell, Dashzeveg Bold, Taeyong Kwon, Velmurugan Balaraman, Patricia Assato, Daniel W Madden, Emily Mantlo, Jayme Souza-Neto, Franco Matias-Ferreyra, Jaime Retallick, Gagandeep Singh, Michael Schotsaert, Mariano Carossino, Udeni B R Balasuriya, William C Wilson, Roman M Pogranichniy, Adolfo García-Sastre, Juergen A Richt
Journal: Emerg Microbes Infect
PubMed ID: 37938158
Doi: 10.1080/22221751.2023.2281356
Products & Services: Molecular Biology Reagents   
RAGE Is a Receptor for SARS-CoV-2 N Protein and Mediates N Protein-induced Acute Lung Injury
Authors: Jie Xia, Jiangmei Wang, Liyang Ying, Ruoqiong Huang, Kai Zhang, Ruoyang Zhang, Wenqi Tang, Qi Xu, Dengming Lai, Yan Zhang, Yaoqin Hu, Xiaodie Zhang, Ruoxi Zang, Jiajie Fan, Qiang Shu, Jianguo Xu
Journal: Am J Respir Cell Mol Biol
PubMed ID: 37478333
Doi: 10.1165/rcmb.2022-0351OC
Products & Services: Recombinant Proteins   
ASPSCR-1 and Sirt-5 alleviate Clonorchis liver fluke rCsNOSIP-induced oxidative stress, proliferation, and migration in cholangiocarcinoma cells
Authors: Meng Bian, Shan Li, Hanzong Zhou, Lijun Bi, Yong Shen, Chen Tingjin, Xinbing Yu, Yan Huang, Qingxia Xu
Journal: PLoS Negl Trop Dis
PubMed ID: 37948465
Doi: 10.1371/journal.pntd.0011727
Products & Services: Gene Synthesis   
Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2)
Authors: Jingbo Yi, Boya Qi, Jian Yin, Ruochong Li, Xudong Chen, Junhan Hu, Guohui Li, Sensen Zhang, Yuebin Zhang, Maojun Yang
Journal: Nat Commun
PubMed ID: 38012235
Doi: 10.1038/s41467-023-43580-w
Structure-directed bioengineering the lid1 of cold-adapted Pseudomonas sp TB11 esterase to boost catalytic capacity
Authors: Linlin Sha, Wen-Sen He, Tian Zheng, Yang Fei, Yu Fang, Huqing Yang, Gang Chen
Journal: Int J Biol Macromol
PubMed ID: 37992944
Doi: 10.1016/j.ijbiomac.2023.128302
Products & Services: Gene Synthesis   
MiR126-targeted-nanoparticles combined with PI3K/AKT inhibitor as a new strategy to overcome melanoma resistance
Authors: Maria Beatrice Arasi, Gabriele De Luca, Laura Chronopoulou, Francesca Pedini, Eleonora Petrucci, Michela Flego, Annarita Stringaro, Marisa Colone, Luca Pasquini, Massimo Spada, Valentina Lulli, Maria Chiara Perrotta, George Adrian Calin, Cleofe Palocci, Mauro Biffoni, Federica Felicetti, Nadia Felli
Journal: Mol Ther
PubMed ID: 37990493
Doi: 10.1016/j.ymthe.2023.11.021
Products & Services: Molecular Biology Reagents   
Isolation and characterisation of PR3-specific B cells and their immunoglobulin sequences
Authors: Shane Kelly, Katherine Jl Jackson, Timothy J Peters, Dan Suan, Christopher C Goodnow
Journal: J Autoimmun
PubMed ID: 37952292
Doi: 10.1016/j.jaut.2023.103129
Products & Services: DNA Sequencing   
Denovo production of resveratrol by engineered Saccharomyces cerevisiae W303-1a using pretreated Gracilaria corticata extracts
Authors: Nishanthika Thenmozhi Kulasekaran, Mary Leema Thilakam, Dharani Gopal, Jung-Kul Lee, Jeya Marimuthu
Journal: Biotechnol Lett
PubMed ID: 37987932
Doi: 10.1007/s10529-023-03441-4
Products & Services: Molecular Biology Reagents   
Development of a highly efficient prime editor system in mice and rabbits
Authors: Yuqiang Qian , Di Wang , Wenchao Niu , Zheng Shi , Mao Wu , Ding Zhao , Jinze Li , Xun Gao , Zhongtian Zhang , Liangxue Lai , Zhanjun Li
Journal: Cell Mol Life Sci .
PubMed ID: 37924393
Doi: 10.1007/s00018-023-05003-3
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Interactions of Histone Deacetylase 6 with DNA Damage Repair Factors Strengthen its Utility as a Combination Drug Target in High-Grade Serous Ovarian Cancer
Authors: Jolene M Duda, Stefani N Thomas
Journal: ACS Pharmacol Transl Sci
PubMed ID: 38107255
Doi: 10.1021/acsptsci.3c00215
Critical role of TPRN rings in the stereocilia for hearing
Authors: Jieyu Qi, Fangzhi Tan, Liyan Zhang, Yinyi Zhou, Ziyu Zhang, Qiuhan Sun, Nianci Li, Yuan Fang, Xin Chen, Yunhao Wu, Guisheng Zhong, Renjie Chai
Journal: Mol Ther
PubMed ID: 37952086
Doi: 10.1016/j.ymthe.2023.11.011
DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones
Authors: Meital Abayev-Avraham, Yehuda Salzberg, Dar Gliksberg, Meital Oren-Suissa, Rina Rosenzweig
Journal: Nat Commun
PubMed ID: 37923706
Doi: 10.1038/s41467-023-42735-z
A role for cytoglobin in regulating intracellular hydrogen peroxide and redox signals in the vasculature
Authors: Clinton Mathai, Frances Jourd'heuil, Le Gia Cat Pham, Kurrim Gilliard, Joseph Balnis, Annie Jen, Katherine A Overmyer, Joshua J Coon, Ariel Jaitovich, Benoit Boivin, David Jourd'heuil
Journal: biorxiv
PubMed ID: 37034694
Doi: 10.1101/2023.03.31.535146
Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment
Authors: Xiang Dong, Chunlu Li, Chengsi Deng, Jingwei Liu, Danni Li, Tingting Zhou, Xindi Yang, Yunchan Liu, Qiqiang Guo, Yanling Feng, Yang Yu, Zhuo Wang, Wendong Guo, Siyi Zhang, Hongyan Cui, Cui Jiang, Xiwen Wang, Xiaoyu Song, Xun Sun, Liu Cao
Journal: Oncogene
PubMed ID: 37952080
Doi: 10.1038/s41388-023-02886-1
A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease
Authors: Fernando Gonzalez-Ortiz, Pamela C L Ferreira, Armand González-Escalante, Laia Montoliu-Gaya, Paula Ortiz-Romero, Przemyslaw R Kac, Michael Turton, Hlin Kvartsberg, Nicholas J Ashton, Henrik Zetterberg, Peter Harrison, Bruna Bellaver, Guilherme Povala, Victor L Villemagne, Tharick A Pascoal, Mary Ganguli, Anne D Cohen, Carolina Minguillon, Jose Contador, Marc Suárez-Calvet, Thomas K Karikari, Kaj Blennow
Journal: Alzheimers Dement
PubMed ID: 37975513
Doi: 10.1002/alz.13525
Plant carbonic anhydrase-like enzymes in neuroactive alkaloid biosynthesis
Authors: Ryan S Nett, Yaereen Dho, Chun Tsai, Daria Passow, Jaime Martinez Grundman, Yun-Yee Low, Elizabeth S Sattely
Journal: Nature
PubMed ID: 37938780
Doi: 10.1038/s41586-023-06716-y
Unlocking the potential of allogeneic Vδ2 T cells for ovarian cancer therapy through CD16 biomarker selection and CAR/IL-15 engineering
Authors: Derek Lee, Zachary Spencer Dunn, Wenbin Guo, Carl J Rosenthal, Natalie E Penn, Yanqi Yu, Kuangyi Zhou, Zhe Li, Feiyang Ma, Miao Li, Tsun-Ching Song, Xinjian Cen, Yan-Ruide Li, Jin J Zhou, Matteo Pellegrini, Pin Wang, Lili Yang
Journal: Nat Commun
PubMed ID: 37938576
Doi: 10.1038/s41467-023-42619-2
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Phages overcome bacterial immunity via diverse anti-defence proteins
Authors: Erez Yirmiya, Azita Leavitt, Allen Lu, Adelyn E Ragucci, Carmel Avraham, Ilya Osterman, Jeremy Garb, Sadie P Antine, Sarah E Mooney, Samuel J Hobbs, Philip J Kranzusch, Gil Amitai, Rotem Sorek
Journal: Nature
PubMed ID: 37992756
Doi: 10.1038/s41586-023-06869-w
Products & Services: Gene Synthesis   
A streamlined, automated workflow to screen and triage large numbers of baculoviruses for protein expression
Authors: James J Kostas, Andrea T Partridge, Noel J Byrne, Richard W Edwards, Hua-Poo Su, Sandra B Gabelli, Alexei Brooun, Jennifer M Shipman
Journal: Protein Expr Purif
PubMed ID: 37995943
Doi: 10.1016/j.pep.2023.106406
Products & Services: Molecular Biology Reagents   
Rational immunosilencing of a promiscuous T-cell epitope in the capsid of an adeno-associated virus
Authors: So Jin Bing, Morten Seirup, Trish T Hoang, Susana S Najera, Collin Britten, Stephanee L Warrington, Shiang-Ling Chu, Ronit Mazor
Journal: Nat Biomed Eng
PubMed ID: 37996615
Doi: 10.1038/s41551-023-01129-8
Products & Services: Peptide Synthesis   
Yeast Metabolic Engineering for Biosynthesis of Caffeic Acid-Derived Phenethyl Ester and Phenethyl Amide
Authors: Zi-Chen Jia, Duo Liu, Hai-Di Ma, Yu-Hui Cui, Hui-Min Li, Xia Li, Ying-Jin Yuan
Journal: ACS Synth Biol
PubMed ID: 38016187
Doi: 10.1021/acssynbio.3c00413
Products & Services: Molecular Biology Reagents   
Development of a multi-epitope vaccine candidate for leishmanial parasites applying immunoinformatics and approaches
Authors: Rahila Qureshi, Insaf Ahmed Qureshi
Journal: Front Immunol
PubMed ID: 38035118
Doi: 10.3389/fimmu.2023.1269774
Products & Services: Molecular Biology Reagents   
Environment relevant exposure of perfluorooctanoic acid accelerates the growth of hepatocellular carcinoma cells through mammalian target of rapamycin (mTOR) signal pathway
Authors: Jiawei Hong, Xiaoyan Wang, Hangbiao Jin, Yuanchen Chen, Yifan Jiang, Keyi Du, Diyu Chen, Shusen Zheng, Linping Cao
Journal: Environ Pollut
PubMed ID: 37967710
Doi: 10.1016/j.envpol.2023.122910
Cationic ribosomal proteins can inhibit pro-inflammatory action stimulated by LPS+HMGB1 and are hindered by advanced glycation end products
Authors: Masahiro Watanabe, Takao Toyomura, Hidenori Wake, Takashi Nishinaka, Omer Faruk Hatipoglu, Hideo Takahashi, Masahiro Nishibori, Shuji Mori
Journal: Biotechnol Appl Biochem
PubMed ID: 38010900
Doi: 10.1002/bab.2538
Products & Services: Molecular Biology Reagents   
Development of an Electrochemical, Aptamer-Based Sensor for Dynamic Detection of Neuropeptide Y
Authors: Jordan M Seibold, Sanduni W Abeykoon, Ashley E Ross, Ryan J White
Journal: ACS Sens
PubMed ID: 38033269
Doi: 10.1021/acssensors.3c00855
Products & Services: Recombinant Proteins   
Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption
Authors: Jin-Gang Yang, Bao Sun, Zheng Wang, Xing Li, Jia-Hui Gao, Jia-Jun Qian, Jiang Li, Wen-Jia Wei, Ping Zhang, Wei Wang
Journal: Cell Death Dis
PubMed ID: 37957146
Doi: 10.1038/s41419-023-06263-4
The Peroxidase gene OsPrx114 Activated by OsWRKY50 Enhances Drought Tolerance through ROS Scavenging in Rice
Authors: Chao Zheng , Xuming Wang , Yue Xu , Shaomin Wang , Xin Jiang e , Xiuli Liub , Weijun Cui , Yueyan Wu , Chengqi Yan , Hongjia Liu , Yin Lu e, Jianping Chen a,b, and Jie Zhou
Journal: Plant Physiology and Biochemistry
Doi: 10.1016/j.plaphy.2023.108138
Unraveling the salt tolerance of Phi29 DNA polymerase using compartmentalized self-replication and microfluidics platform
Authors: Yaping Sun , Danny Hsu Ko , Jie Gao , Kang Fu , Yaping Gao , Qiwen Zhang , Salem Baldi , Tao Hong , Igor Ivanov , Yun He , Hui Tian
Journal: Front Microbiol .
PubMed ID: 38029082
Doi: 10.3389/fmicb.2023.1267196
Products & Services: Plasmid DNA Preparation   
Oncolytic adenoviruses expressing checkpoint inhibitors for cancer therapy
Authors: Daoyuan Xie , Yaomei Tian , Die Hu , Yuanda Wang , Yuling Yang , Bailing Zhou , Rui Zhang , Zhixiang Ren , Mohan Liu , Jie Xu , Chunyan Dong , Binyan Zhao , Li Yang
Journal: Signal Transduct Target Ther .
PubMed ID: 38016957
Doi: 10.1038/s41392-023-01683-2
Structural insights into asymmetric activation of the calciumsensing receptor–Gq complex
Authors: Shenglong Ling, Xianyu Meng, Yuan Zhang, Zhemin Xia, Yingxin Zhou, Fan Yang, Pan Shi, Chaowei Shi, Changlin Tian
Journal: Cell Res .
PubMed ID: 37919470
Doi: 10.1038/s41422-023-00892-2
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Heterogeneity in the progression of retinal pathologies in mice harboring patient mimicking Impg2 mutations
Authors: Brittany N Williams, Adam Draper, Patrick F Lang, Tylor R Lewis, Audrey L Smith, Steven J Mayerl, Marie Rougié, Jeremy M Simon, Vadim Y Arshavsky, Scott H Greenwald, David M Gamm, Isabel Pinilla, Benjamin D Philpot
Journal: Hum Mol Genet
PubMed ID: 37975905
Doi: 10.1093/hmg/ddad199
IL-27 regulates NLRP3 inflammasome activation of MDSCs in experimental Sjögren's syndrome
Authors: Xiaoyu Xia, Qiqiang Long, Jie Zha, Tingting Jiang, Junqiao Guo, Bo Jiang, Xiaojing Li, Genhong Yao
Journal: Int Immunol
PubMed ID: 37756640
Doi: 10.1093/intimm/dxad037
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Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease
Authors: Yael Gruper, Anette S B Wolff, Liad Glanz, Frantisek Spoutil, Mihaela Cuida Marthinussen, Adriana Osickova, Yonatan Herzig, Yael Goldfarb, Goretti Aranaz-Novaliches, Jan Dobeš, Noam Kadouri, Osher Ben-Nun, Amit Binyamin, Bar Lavi, Tal Givony, Razi Khalaila, Tom Gome, Tomáš Wald, Blanka Mrazkova, Carmel Sochen, Marine Besnard, Shifra Ben-Dor, Ester Feldmesser, Elisaveta M Orlova, Csaba Hegedűs, István Lampé, Tamás Papp, Szabolcs Felszeghy, Radislav Sedlacek, Esti Davidovich, Noa Tal, Dror S Shouval, Raanan Shamir, Carole Guillonneau, Zsuzsa Szondy, Knut E A Lundin, Radim Osicka, Jan Prochazka, Eystein S Husebye, Jakub Abramson
Journal: Nature
PubMed ID: 37993717
Doi: 10.1038/s41586-023-06776-0
Mechanism of δ Mediated Transcription Activation in Bacillus subtilis: Interaction with α CTD of RNA Polymerase Stabilizes δ and Successively Facilitates the Open Complex Formation
Authors: Aniruddha Tewary, Ranjit Kumar Prajapati, Jayanta Mukhopadhyay
Journal: J Mol Biol
PubMed ID: 37972688
Doi: 10.1016/j.jmb.2023.168366
RNA is a key component of extracellular DNA networks in Pseudomonas aeruginosa biofilms
Authors: Sudarsan Mugunthan, Lan Li Wong, Fernaldo Richtia Winnerdy, Stephen Summers, Muhammad Hafiz Bin Ismail, Yong Hwee Foo, Tavleen Kaur Jaggi, Oliver W Meldrum, Pei Yee Tiew, Sanjay H Chotirmall, Scott A Rice, Anh Tuân Phan, Staffan Kjelleberg, Thomas Seviour
Journal: Nat Commun
PubMed ID: 38012164
Doi: 10.1038/s41467-023-43533-3
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Effects of protoscoleces excretory-secretory products of Echinococcus granulosus on hepatocyte growth, function, and glucose metabolism
Authors: Guangyi Luo, Haiwen Li, Qiong Lu, Jiangtao Cao, Hailong Lv, Yufeng Jiang
Journal: Acta Trop
PubMed ID: 37944837
Doi: 10.1016/j.actatropica.2023.107066
Products & Services: Molecular Biology Reagents   
Ana Castillo Discusses Sexuality, Identity, and Life-Then and Now
Authors: Liliana C Gonzalez, Stacy I Macias
Journal: J Lesbian Stud
PubMed ID: 37791458
Doi: 10.1080/10894160.2023.2250670
Products & Services: Plasmid DNA Preparation   
Diurnal regulation of alternative splicing associated with thermotolerance in rice by two glycine-rich RNA-binding proteins
Authors: Chuang Yang, Anni Luo, Hai-Ping Lu, Seth Jon Davis, Jian-Xiang Liu
Journal: Sci Bull (Beijing)
PubMed ID: 38044192
Doi: 10.1016/j.scib.2023.11.046
Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2
Authors: Shengnan Zhu, Qingning Yuan, Xinzhu Li, Xinheng He, Shiyi Shen, Dongxue Wang, Junrui Li, Xi Cheng, Xiaoqun Duan, H Eric Xu, Jia Duan
Journal: Cell Rep
PubMed ID: 37952153
Doi: 10.1016/j.celrep.2023.113406
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Non-canonical MLL1 activity regulates centromeric phase separation and genome stability
Authors: Liang Sha, Zi Yang, Sojin An, Wentao Yang, Sungmin Kim, Hoon Oh, Jing Xu, Jun Yin, He Wang, Heinz-Josef Lenz, Woojin An, Uhn-Soo Cho, Yali Dou
Journal: Nat Cell Biol
PubMed ID: 37945831
Doi: 10.1038/s41556-023-01270-1
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ZNF70 regulates IL-1β secretion of macrophages to promote the proliferation of HCT116 cells via activation of NLRP3 inflammasome and STAT3 pathway in colitis-associated colorectal cancer
Authors: Zhihong Zhang, Mingyue Li, Yi Tai, Yue Xing, Hongxiang Zuo, Xuejun Jin, Juan Ma
Journal: Cell Signal
PubMed ID: 38000525
Doi: 10.1016/j.cellsig.2023.110979
Products & Services: Molecular Biology Reagents   
Covalent Peptide LSD1 Inhibitor Specifically Recognizes Cys360 in the Enzyme-Active Region
Authors: Qinhong Luo , Yue Ma , Huiting Liang , Yuan Feng , Na Liu, Chenshan Lian , Lizhi Zhu , Yuxin Ye , Zhihong Liu , Zhanfeng Hou , Sijin Chen , Yaqi Wang , Chuan Dai , Chunli Song , Min Zhang , Zhipeng He , Yun Xing , Wanjin Zhong , Shuiming Li , Jianlong Wu , Fei Lu , Feng Yin , Zigang Li
Journal: J Med Chem .
PubMed ID: 37922441
Doi: 10.1021/acs.jmedchem.3c01549
Products & Services: Gene Synthesis   
An mRNA-based platform for the delivery of pathogen-specific IgA into mucosal secretions
Authors: Cailin E Deal, Angelene F Richards, Tracy Yeung, Max J Maron, Ziqiu Wang, Yen-Ting Lai, Brian R Fritz, Sunny Himansu, Elisabeth Narayanan, Ding Liu, Rositsa Koleva, Stuart Licht, Chiaowen J Hsiao, Ivana L Rajlic, Hillary Koch, Michael Kleyman, Mark E Pulse, William J Weiss, Jennifer E Doering, Samantha K Lindberg, Nicholas J Mantis, Andrea Carfi, Obadiah J Plante
Journal: Cell Rep Med
PubMed ID: 37918405
Doi: 10.1016/j.xcrm.2023.101253
Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA)
Authors: Cheng-Wei Cheng, Chung-Yi Wu, Szu-Wen Wang, Jia-Yan Chen, Chih-Chuan Kung, Kuo-Shiang Liao, Chi-Huey Wong
Journal: Proc Natl Acad Sci U S A
PubMed ID: 38011546
Doi: 10.1073/pnas.2314392120
Development of a sandwich ELISA to detect circulating, soluble IRAP as a potential disease biomarker
Authors: Anika Vear, Claudia Thalmann, Kristina Youngs, Natalie Hannan, Tracey Gaspari, Siew Yeen Chai
Journal: Sci Rep
PubMed ID: 38001104
Doi: 10.1038/s41598-023-44038-1
Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19
Authors: Tomas O Jensen, Greg A Grandits, Mamta K Jain, Thomas A Murray, Birgit Grund, Kathryn Shaw-Saliba, Michael A Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V Baker, Peter Chen, Robin L Dewar, Anna L Goodman, Timothy J Hatlen, Helene C Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G Leshnower, David Looney, Charalampos D Moschopoulos, Henry Mugerwa, Daniel D Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M Tauseef Rehman, Adam Rupert, Randy A Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R Ko
Journal: J Infect Dis
PubMed ID: 37948759
Doi: 10.1093/infdis/jiad446
Self-Entrapment of Antimicrobial Peptides in Silica Particles for Stable and Effective Antimicrobial Peptide Delivery System
Authors: Mi-Ran Ki, Sung Ho Kim, Tae In Park, Seung Pil Pack
Journal: Int J Mol Sci
PubMed ID: 38003614
Doi: 10.3390/ijms242216423
Products & Services: Peptide Synthesis   
Engineering U1-Based Tetracycline-Inducible Riboswitches to Control Gene Expression in Mammals
Authors: Eric Rovira, Beatriz Moreno, Nerea Razquin, Lorea Blázquez, Ruben Hernández-Alcoceba, Puri Fortes, Fernando Pastor
Journal: ACS Nano
PubMed ID: 37971502
Doi: 10.1021/acsnano.3c01994
Products & Services: Molecular Biology Reagents   
Acidic pH or salt treatment can convert soluble antibody aggregates in culture harvest into monomers and improve Protein A chromatography step yield
Authors: Ting Zhang, Bin Li, Wanyuan Dong, Yan Wan, Yifeng Li
Journal: Protein Expr Purif
PubMed ID: 37939750
Doi: 10.1016/j.pep.2023.106391
Cardiac myosin-binding protein C N-terminal interactions with myosin and actin filaments: Opposite effects of phosphorylation and M-domain mutations
Authors: Fiona L Wong, Thomas A Bunch, Victoria C Lepak, Allison L Steedman, Brett A Colson
Journal: J Mol Cell Cardiol
PubMed ID: 38008210
Doi: 10.1016/j.yjmcc.2023.11.010
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Genetic manipulation of giant viruses and their host, Acanthamoeba castellanii
Authors: Nadege Philippe, Avi Shukla, Chantal Abergel, Hugo Bisio
Journal: Nat Protoc
PubMed ID: 37964008
Doi: 10.1038/s41596-023-00910-y
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Structural and biophysical properties of a [4Fe4S] ferredoxin-like protein from Synechocystis sp PCC 6803 with a unique two domain structure
Authors: Effie Kisgeropoulos, Vivek S Bharadwaj, Anastasia Ledinina, Carolyn E Lubner, David W Mulder, Sharon L Smolinski, Marko Boehm, Kirstin Gutekunst, Paul W King, Drazenka Svedruzic
Journal: J Inorg Biochem
PubMed ID: 38008043
Doi: 10.1016/j.jinorgbio.2023.112428
Products & Services: DNA Sequencing   
Sirtuin 3-mediated deacetylation of superoxide dismutase 2 ameliorates sodium fluoride-induced mitochondrial dysfunction in porcine oocytes
Authors: Xin-Yue Qi, Jin-Dong Yuan, Zi-Yu Liu, Xi-Qing Jiang, Qi Zhang, Shan-Long Zhang, Lu Zhao, Ling-Yan Ke, Chen-Yuan Zhang, Yan Li, Lu-Yan Zhang, Qian-Qian Xu, Zhong-Hua Liu, Jing-Tao Sun, Jun-Xue Jin
Journal: Sci Total Environ
PubMed ID: 37944611
Doi: 10.1016/j.scitotenv.2023.168306
Protein kinase PfPK2 mediated signalling is critical for host erythrocyte invasion by malaria parasite
Authors: Rahul Singh Rawat, Ankit Gupta, Neelam Antil, Sonika Bhatnagar, Monika Singh, Akanksha Rawat, T S Keshava Prasad, Pushkar Sharma
Journal: PLoS Pathog
PubMed ID: 37988347
Doi: 10.1371/journal.ppat.1011770
Targeting the COMMD4-H2B protein complex in lung cancer
Authors: Ming Tang, Joshua T Burgess, Mark Fisher, Didier Boucher, Emma Bolderson, Neha S Gandhi, Kenneth J O'Byrne, Derek J Richard, Amila Suraweera
Journal: Br J Cancer
PubMed ID: 37914802
Doi: 10.1038/s41416-023-02476-8
Regioselective Glycosylation of Polyphenols by Family 1 Glycosyltransferases: Experiments and Simulations
Authors: Ruben M de Boer, Dovydas Vaitkus, Kasper Enemark-Rasmussen, Sören Maschmann, David Teze, Ditte H Welner
Journal: ACS Omega
PubMed ID: 38075805
Doi: 10.1021/acsomega.3c08255
Extracellular electron uptake from a cathode by the lactic acid bacterium
Authors: Sara Tejedor-Sanz, Siliang Li, Biki Bapi Kundu, Caroline M Ajo-Franklin
Journal: Front Microbiol
PubMed ID: 38075918
Doi: 10.3389/fmicb.2023.1298023
Products & Services: Molecular Biology Reagents   
Comparative Computational Analysis of Spike Protein Structural Stability in SARS-CoV-2 Omicron Subvariants
Authors: Anand Balupuri, Jeong-Min Kim, Kwang-Eun Choi, Jin Sun No, Il-Hwan Kim, Jee Eun Rhee, Eun-Jin Kim, Nam Sook Kang
Journal: Int J Mol Sci
PubMed ID: 38003257
Doi: 10.3390/ijms242216069
Products & Services: Molecular Biology Reagents   
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells
Authors: Jing Cheng, Yutong Wang, Lizheng Yin, Wenzhang Liang, Jing Zhang, Cuiqing Ma, Yu Zhang, Bo Liu, Jiachao Wang, Weiting Zhao, Miao Li, Lin Wei
Journal: MBio
PubMed ID: 37909764
Doi: 10.1128/mbio.01480-23
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IRGM is a novel regulator of PD-L1 via promoting S6K1-mediated phosphorylation of YBX1 in hepatocellular carcinoma
Authors: Junnan Ru, Jiahua Lu, Jiangzhen Ge, Bo Ding, Rong Su, Yifan Jiang, Yujing Sun, Jun Ma, Yu Li, Jingqi Sun, Guangming Xu, Rongliang Tong, Shusen Zheng, Beng Yang, Jian Wu
Journal: Cancer Lett
PubMed ID: 37993085
Doi: 10.1016/j.canlet.2023.216495
Products & Services: Recombinant Antibody Expression   
Mechanism of actin capping protein recruitment and turnover during clathrin-mediated endocytosis
Authors: Andrew K Lamb, Andres N Fernandez, Abdunaser Eadaim, Katelyn Johnson, Santiago M Di Pietro
Journal: J Cell Biol
PubMed ID: 37966720
Doi: 10.1083/jcb.202306154
Products & Services: Peptide Synthesis   
Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry
Authors: Haofeng Wang, Qi Yang, Xiaoce Liu, Zili Xu, Maolin Shao, Dongxu Li, Yinkai Duan, Jielin Tang, Xianqiang Yu, Yumin Zhang, Aihua Hao, Yajie Wang, Jie Chen, Chenghao Zhu, Luke Guddat, Hongli Chen, Leike Zhang, Xinwen Chen, Biao Jiang, Lei Sun, Zihe Rao, Haitao Yang
Journal: Nat Commun
PubMed ID: 37990007
Doi: 10.1038/s41467-023-42527-5
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Retraction: Epitopes screening and vaccine molecular design of SADS-CoV based on immunoinformatics
Authors:
Journal: Front Vet Sci
PubMed ID: 38105774
Doi: 10.3389/fvets.2023.1342203
Products & Services: Gene Synthesis   
Delineation of DNA and mRNA COVID-19 vaccine-induced immune responses in preclinical animal models
Authors: Viviane M Andrade, Igor Maricic, Richa Kalia, Lauren Jachimowicz, Olivia Bedoya, Daniel W Kulp, Laurent Humeau, Trevor R F Smith
Journal: Hum Vaccin Immunother
PubMed ID: 38012018
Doi: 10.1080/21645515.2023.2281733
Antagonistic conflict between transposon-encoded introns and guide RNAs
Authors: Rimantė Žedaveinytė, Chance Meers, Hoang C Le, Edan E Mortman, Stephen Tang, George D Lampe, Sanjana R Pesari, Diego R Gelsinger, Tanner Wiegand, Samuel H Sternberg
Journal: biorxiv
PubMed ID: 38045383
Doi: 10.1101/2023.11.20.567912
Products & Services: Molecular Biology Reagents   
A Versatile Platform to Generate Prodrugs with Rapid and Precise Albumin Hitchhiking and High Cargo Loading for Tumor-Targeted Chemotherapy
Authors: Jing Li, Huimin Xing, Jie Chen, Hongyu Lu, Ze Tao, Yiran Tao, Yunqing Sun, Tao Su, Xin Li, Huansheng Chang, Shiyuan Chen, Zhuo Chen, Hao Yang, Jingqiu Cheng, Hong Zhu, Xiaofeng Lu
Journal: Small
PubMed ID: 37963821
Doi: 10.1002/smll.202304253
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Novel and unique rheumatoid factors cross-react with viral epitopes in COVID-19
Authors: Maya F Amjadi, Maxwell H Parker, Ryan R Adyniec, Zihao Zheng, Alex M Robbins, S Janna Bashar, Michael F Denny, Sara S McCoy, Irene M Ong, Miriam A Shelef
Journal: J Autoimmun
PubMed ID: 37956528
Doi: 10.1016/j.jaut.2023.103132
Reconstruction of dynamic mammary mini gland in vitro for normal physiology and oncogenesis
Authors: Lei Yuan, Shaofang Xie, Huiru Bai, Xiaoqin Liu, Pei Cai, Jing Lu, Chunhui Wang, Zuobao Lin, Shuying Li, Yajing Guo, Shang Cai
Journal: Nat Methods
PubMed ID: 37919421
Doi: 10.1038/s41592-023-02039-y
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