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High levels of alpha-gal with large variation in the salivary glands of lone star ticks fed on human blood

Authors: L Paulina Maldonado-Ruiz, Kathryn E Reif, Anuradha Ghosh, Stephanie Foré, Rachel L Johnson, Yoonseong Park

Journal: Sci Rep

PubMed ID: 38049505

Doi: 10.1038/s41598-023-48437-2

Products & Services: Molecular Biology Reagents

Publisher Correction: CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides

Authors: Guillaume Gaud, Sooraj Achar, François X P Bourassa, John Davies, Teri Hatzihristidis, Seeyoung Choi, Taisuke Kondo, Selamawit Gossa, Jan Lee, Paul Juneau, Naomi Taylor, Christian S Hinrichs, Dorian B McGavern, Paul François, Grégoire Altan-Bonnet, Paul E Love

Journal: Nat Immunol

PubMed ID: 38057618

Doi: 10.1038/s41590-023-01725-5

Products & Services: Peptide Synthesis

Generation and Characterization of SORT1-Targeted Antibody-Drug Conjugate for the Treatment of SORT1-Positive Breast Tumor

Authors: Weiliang Zhuang, Wei Zhang, Liping Xie, Lei Wang, Yuan Li, Ziyu Wang, Ao Zhang, Haitao Qiu, Jun Feng, Baohong Zhang, Youjia Hu

Journal: Int J Mol Sci

PubMed ID: 38139459

Doi: 10.3390/ijms242417631

Products & Services: Monoclonal Antibody Services

Enhancing CAR-T cells: unleashing lasting impact potential with phytohemagglutinin activation in in vivo leukemia model

Authors: Berranur Sert, Gamze Gulden, Tarik Teymur, Yasin Ay, Raife Dilek Turan, Onur Mert Unaldi, Elanur Guzenge, Hamza Emir Erdil, Sevim Isik, Pinar Oz, Ilknur Bozkurt, Samed Ozer, Tahire Yurdakul, Osman Kamali, Ercument Ovali, Nevzat Tarhan, Cihan Tastan

Journal: Cancer Gene Ther

PubMed ID: 38092962

Doi: 10.1038/s41417-023-00709-9

Products & Services: Custom Vector Construction

Structural basis of branching during RNA splicing

Authors: Daniel B Haack, Boris Rudolfs, Cheng Zhang, Dmitry Lyumkis, Navtej Toor

Journal: Nat Struct Mol Biol

PubMed ID: 38057551

Doi: 10.1038/s41594-023-01150-0

Products & Services: Gene Synthesis

Surrogate Virus Neutralisation Test Based on Nanoluciferase-Tagged Antigens to Quantify Inhibitory Antibodies against SARS-CoV-2 and Characterise Omicron-Specific Reactivity in a Vaccination Cohort

Authors: Michael Schoefbaenker, Rieke Neddermeyer, Theresa Guenther, Marlin M Mueller, Marie-Luise Romberg, Nica Classen, Marc T Hennies, Eike R Hrincius, Stephan Ludwig, Joachim E Kuehn, Eva U Lorentzen

Journal: Vaccines (Basel)

PubMed ID: 38140236

Doi: 10.3390/vaccines11121832

Products & Services: Plasmid DNA Preparation

Humoral and cellular immunogenicity and efficacy of a coxsackievirus A10 vaccine in mice

Authors: Huan-Huan An, Meng Li, Rui-Lun Liu, Jie Wu, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Sha-Sha Qian, Shuo Shen

Journal: Emerg Microbes Infect

PubMed ID: 36373411

Doi: 10.1080/22221751.2022.2147022

Products & Services: Catalog Peptides

SAXS/WAXS data of conformationally flexible ribose binding protein

Authors: Jagrity Choudhury, Kento Yonezawa, Anu Anu, Nobutaka Shimizu, Barnali Chaudhuri

Journal: Data Brief

PubMed ID: 38178847

Doi: 10.1016/j.dib.2023.109932

Products & Services: Molecular Biology Reagents

Discovery of GPX4 inhibitors through FP-based high-throughput screening

Authors: Yu Cao, Bin Wu, Ying Xu, Mingchen Wang, Xinyu Wu, Xiaochen Liang, Jin Lin, Zhihai Li, Hua Lin, Cheng Luo, Shijie Chen

Journal: Eur J Med Chem

PubMed ID: 38145603

Doi: 10.1016/j.ejmech.2023.116044

Products & Services: Catalog Peptides

Photosensitizer-singlet oxygen sensor conjugated silica nanoparticles for photodynamic therapy and bioimaging

Authors: Jeladhara Sobhanan, Kenji Ono, Takuya Okamoto, Makoto Sawada, Paul S Weiss, Vasudevanpillai Biju

Journal: Chem Sci

PubMed ID: 38332815

Doi: 10.1039/d3sc03877g

Products & Services: Molecular Biology Reagents

Antibodies to D7L salivary proteins as a new serological tool to estimate human exposure to mosquitoes

Authors: Sophana Chea, Laura Willen, Sreynik Nhek, Piseth Ly, Kristina Tang, James Oristian, Roberto Salas-Carrillo, Aiyana Ponce, Paola Carolina Valenzuela Leon, Dara Kong, Sokna Ly, Ratanak Sath, Chanthap Lon, Rithea Leang, Rekol Huy, Christina Yek, Jesus G Valenzuela, Eric Calvo, Jessica E Manning, Fabiano Oliveira

Journal: medrxiv

PubMed ID: 38318204

Doi: 10.1101/2023.12.22.23300438

Products & Services: Proteins, Expression, Isolation and Analysis

Cell cycle status of male and female gametes during Arabidopsis reproduction

Authors: Yoav Voichek, Bohdana Hurieva, Caroline Michaud, Anna Schmücker, Zaida Vergara, Bénédicte Desvoyes, Crisanto Gutierrez, Viktoria Nizhynska, Benjamin Jaegle, Michael Borg, Frédéric Berger, Magnus Nordborg, Mathieu Ingouff

Journal: Plant Physiol

PubMed ID: 37757882

Doi: 10.1093/plphys/kiad512

Products & Services: Gene Synthesis

Identification of selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors and their effects on tau and microtubule

Authors: Yi-Wen Wu, Wei-Chun HuangFu, Tony Eight Lin, Chao-Hsiang Peng, Huang-Ju Tu, Ting-Yi Sung, Tzu-Ying Sung, Shih-Chung Yen, Shiow-Lin Pan, Kai-Cheng Hsu

Journal: Int J Biol Macromol

PubMed ID: 38163507

Doi: 10.1016/j.ijbiomac.2023.129074

Products & Services: ORF cDNA Clones/MolecularCloud

Injectable CNPs/DMP1-loaded self-assembly hydrogel regulating inflammation of dental pulp stem cells for dentin regeneration

Authors: Yue Zhao, Lutong Song, Mengchen Li, Haoran Peng, Xinyi Qiu, Yuyang Li, Bijun Zhu, Chao Liu, Shuangshuang Ren, Leiying Miao

Journal: Mater Today Bio

PubMed ID: 38170028

Doi: 10.1016/j.mtbio.2023.100907

Products & Services: Proteins, Expression, Isolation and Analysis

Interaction between membrane curvature sensitive factors SpoVM and SpoIVA in Bicelle condition

Authors: Jiali Chen, Yifan Wang, Shuru Lin, Quanxiang Yu, Zhengfei Qi, Wenqi Jiang, Qiang Zhao, Qingshan Bill Fu

Journal: Biochem Biophys Res Commun

PubMed ID: 38141557

Doi: 10.1016/j.bbrc.2023.149395

Products & Services: Recombinant Proteins

Molecular characterization and functional analysis of peroxiredoxin 1 (Prx1) from roughskin sculpin (Trachidermus fasciatus)

Authors: Yingying Liu, Haiyan Cong, Caihong Bi, Haidong Zha, Shanshan Yu, Lihua Zhao, Qian Zhu

Journal: Fish Physiol Biochem

PubMed ID: 38103084

Doi: 10.1007/s10695-023-01281-7

Products & Services: Molecular Biology Reagents

Systemic treatment with ubiquitin carboxy terminal hydrolase L1 TAT protein ameliorates axonal injury and reduces functional deficits after traumatic brain injury in mice

Authors: Zhiping Mi, Jie Ma, Dennis J Zeh, Marie E Rose, Jeremy J Henchir, Hao Liu, Xiecheng Ma, Guodong Cao, C Edward Dixon, Steven H Graham

Journal: Exp Neurol

PubMed ID: 38092186

Doi: 10.1016/j.expneurol.2023.114650

Products & Services: Proteins, Expression, Isolation and Analysis

Use of recombinant malate dehydrogenase (MDH) and superoxide dismutase (SOD) [CuZn] as antigens in indirect ELISA for diagnosis of bovine brucellosis

Authors: Rafaella Silva Andrade, Angélica Rosa Faria, Hélida Monteiro Andrade, Júlio Sílvio de Sousa Bueno Filho, Herman Sander Mansur, Alexandra Ancelmo Piscitelli Mansur, Andrey Pereira Lage, Elaine Maria Seles Dorneles

Journal: J Microbiol Methods

PubMed ID: 38101579

Doi: 10.1016/j.mimet.2023.106874

Products & Services: Recombinant Proteins

Design and Engineering of Light-Induced Base Editors Facilitating Genome Editing with Enhanced Fidelity

Authors: Yangning Sun, Qi Chen, Yanbing Cheng, Xi Wang, Zixin Deng, Fuling Zhou, Yuhui Sun

Journal: Adv Sci (Weinh)

PubMed ID: 38039441

Doi: 10.1002/advs.202305311

Products & Services: Gene Synthesis

Tumor-Reactive CD8+ T Cells Enter a TCF1+PD-1- Dysfunctional State

Authors: Jessica J Roetman, Megan M Erwin, Michael W Rudloff, Natalie R Favret, Carlos R Detrés Román, Minna K I Apostolova, Kristen A Murray, Ting-Fang Lee, Youngmin A Lee, Mary Philip

Journal: Cancer Immunol Res

PubMed ID: 37844197

Doi: 10.1158/2326-6066.CIR-22-0939

Products & Services: Peptide Synthesis

Covalent PROTAC design method based on a sulfonyl pyridone probe

Authors: Qinhong Luo , Yaqi Wang , Zhanfeng Hou , Huiting Liang , Licheng Tu , Yun Xing , Chuan Wan , Jianbo Liu , Rui Wang , Lizhi Zhu , Wei Han , Jianlong Wu , Fei Lu , Feng Yin , Zigang Li

Journal: Chem Commun (Camb) .

PubMed ID: 38054347

Doi: 10.1039/d3cc05127g

Products & Services: Gene Synthesis

Inhalation of taraxasterol loaded mixed micelles for the treatment of idiopathic pulmonary fibrosis

Authors: Tong Zhang , Chao Sun , Shubin Yang , Zimin Cai , Sifeng Zhu , Wendian Liu , Yun Luan , Cheng Wang

Journal: Chinese Chemical Letters

Doi: 10.1016/j.cclet.2023.109248

Products & Services: Recombinant Proteins

Molecular basis of Spns2-facilitated sphingosine-1-phosphate transport

Authors: Bin Pang , Leiye Yu , Tong Li , Haizhan Jiao , Xiaomei Wu , Jinxin Wang , Ruiping He , Yurou Zhang , Juan Wang , Hongli Hu , Wei Dai , Li Chen , Ruobing Ren

Journal: Cell Res .

PubMed ID: 38123824

Doi: 10.1038/s41422-023-00908-x

Products & Services: GenCrispr Cas9 Genome Editing

Pal power: Demonstration of the functional association of the Helicobacter pylori flagellar motor with peptidoglycan-associated lipoprotein (Pal) and its preliminary crystallographic analysis

Authors: Xiaotian Zhou, Mohammad M Rahman, Sharmin Q Bonny, Yue Xin, Nikki Liddelow, Mohammad F Khan, Alexandra Tikhomirova, Jihane Homman-Ludiye, Anna Roujeinikova

Journal: Biosci Trends

PubMed ID: 38072447

Doi: 10.5582/bst.2023.01278

Products & Services: Proteins, Expression, Isolation and Analysis

NITR12+ NK Cells Release Perforin to Mediate IgMhi B Cell Killing in Turbot (Scophthalmus maximus)

Authors: Wei Wang, Ying Wang, Jin Yang, Qin Liu, Yuanxing Zhang, Dahai Yang

Journal: J Immunol

PubMed ID: 37843506

Doi: 10.4049/jimmunol.2300281

Products & Services: Proteins, Expression, Isolation and Analysis

A new gene family (BAPs) of bracovirus induces apoptosis of host hemocytes

Authors: Ze-Hua Wang, Xi-Qian Ye, Xiao-Tong Wu, Zhi-Zhi Wang, Jian-Hua Huang, Xue-Xin Chen

Journal: Virulence

PubMed ID: 36694288

Doi: 10.1080/21505594.2023.2171691

Products & Services: Peptide Synthesis

Structural and biochemical investigations of a HEAT-repeat protein involved in the cytosolic iron-sulfur cluster assembly pathway

Authors: Sheena Vasquez, Melissa D Marquez, Edward J Brignole, Amanda Vo, Sunnie Kong, Christopher Park, Deborah L Perlstein, Catherine L Drennan

Journal: Commun Biol

PubMed ID: 38110506

Doi: 10.1038/s42003-023-05579-3

Products & Services: Molecular Biology Reagents

Development of Self-Assembled Protein Nanocage Spatially Functionalized with HA Stalk as a Broadly Cross-Reactive Influenza Vaccine Platform

Authors: Jaeyoung Park, Julie A Champion

Journal: ACS Nano

PubMed ID: 38084728

Doi: 10.1021/acsnano.3c07669

Products & Services: Molecular Biology Reagents

The 4-1BBζ costimulatory domain in chimeric antigen receptors enhances CD8+ T-cell functionality following T-cell receptor stimulation

Authors: Gerard J Chu, Charles G Bailey, Rajini Nagarajah, Sharon M Sagnella, Stephen Adelstein, John E J Rasko

Journal: Cancer Cell Int

PubMed ID: 38105188

Doi: 10.1186/s12935-023-03171-7

Products & Services: Proteins, Expression, Isolation and Analysis

Conserved Residues at the Mtr4 C-Terminus Coordinate Helicase Activity and Exosome Interactions

Authors: Matthew K Yim, Catherine J Stuart, Markell I Pond, Ambro van Hoof, Sean J Johnson

Journal: Biochemistry

PubMed ID: 38085597

Doi: 10.1021/acs.biochem.3c00401

Products & Services: Gene Synthesis

Bisphenol A induces non-alcoholic fatty liver disease by promoting the O-GlcNAcylation of NLRP3

Authors: Yonghong Zhang, Shujuan Han, Tian Li, Li Zhu, Feng Wei

Journal: Arch Physiol Biochem

PubMed ID: 38038745

Doi: 10.1080/13813455.2023.2288533

Products & Services: Molecular Biology Reagents

The Raf-like MAPKKKs STY8, STY17, and STY46 negatively regulate Botrytis cinerea resistance by limiting MKK7 protein accumulation in Arabidopsis

Authors: Lijuan Chen, Jiahui Xiao, You Li, Yuxiao Song, Jun Liu, Qi Zhou, Ting Sun, Hong-Bin Wang, Bing Liu

Journal: Plant J

PubMed ID: 38059690

Doi: 10.1111/tpj.16578

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Regional abundances of binder of sperm (BSP) proteins are negatively associated with the quality of frozen-thawed bovine spermatozoa

Authors: Edgar A Diaz-Miranda, Lauren E Hamilton, Michal Zigo, Lindsey Fallon, M Sofia Ortega, Mayra E Ortiz D'Avila Assumpção, José D Guimarães, Peter Sutovsky

Journal: Reproduction

PubMed ID: 37874784

Doi: 10.1530/REP-23-0305

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Overexpression of endogenous multi-copper oxidases mcoA and mcoC in Rhodococcus jostii RHA1 enhances lignin bioconversion to 2,4-pyridine-dicarboxylic acid

Authors: Goran M M Rashid, Victoria Sodré, Jia Luo, Timothy D H Bugg

Journal: Biotechnol Bioeng

PubMed ID: 38079064

Doi: 10.1002/bit.28620

Products & Services: Gene Synthesis

IP8: A quantitatively minor inositol pyrophosphate signaling molecule that punches above its weight

Authors: Chunfang Gu, Xingyao Li, Guangning Zong, Huanchen Wang, Stephen B Shears

Journal: Adv Biol Regul

PubMed ID: 38064879

Doi: 10.1016/j.jbior.2023.101002

Products & Services: Proteins, Expression, Isolation and Analysis

Green synthesis of silver nanoparticles by using Allium sativum extract and evaluation of their electrical activities in bio-electrochemical cell

Authors: Md Ohiduzzaman, M N I Khan, K A Khan, Bithi Paul

Journal: Nanotechnology

PubMed ID: 38029451

Doi: 10.1088/1361-6528/ad10e4

Products & Services: Proteins, Expression, Isolation and Analysis

SRSF10 facilitates HCC growth and metastasis by suppressing CD8T cell infiltration and targeting SRSF10 enhances anti-PD-L1 therapy

Authors: Xiangyuan Luo, Zerui Zhang, Siwen Li, Yijun Wang, Mengyu Sun, Dian Hu, Junqing Jiang, Yufei Wang, Xiaoyu Ji, Xiaoping Chen, Bixiang Zhang, Huifang Liang, Yiwei Li, Bifeng Liu, Xiao Xu, Shuai Wang, Shengjun Xu, Yongzhan Nie, Kaichun Wu, Daiming Fan, Danfei Liu, Wenjie Huang, Limin Xia

Journal: Int Immunopharmacol

PubMed ID: 38113691

Doi: 10.1016/j.intimp.2023.111376

Products & Services: Molecular Biology Reagents

Global gene regulatory network underlying miR165a in Arabidopsis shoot apical meristem

Authors: Sonali Sinha, Sudeep Sahadevan, Carolyn Ohno, Hasthi Ram, Marcus G Heisler

Journal: Sci Rep

PubMed ID: 38097643

Doi: 10.1038/s41598-023-49093-2

Products & Services: Molecular Biology Reagents

Characterization of human XPD helicase activity with Single Molecule Magnetic Tweezers

Authors: Chunfeng Mao, Maria Mills

Journal: Biophys J

PubMed ID: 38111195

Doi: 10.1016/j.bpj.2023.12.014

Products & Services: CRISPR Cell Lines

CRISPR loss of function screening to identify genes involved in human primordial germ cell-like cell development

Authors: Young Sun Hwang, Yasunari Seita, M Andrés Blanco, Kotaro Sasaki

Journal: PLoS Genet

PubMed ID: 38091369

Doi: 10.1371/journal.pgen.1011080

Products & Services: Gene Synthesis

The 6-Month Antibody Durability of Heterologous Convidecia Plus CoronaVac and Homologous CoronaVac Immunizations in People Aged 18-59 Years and over 60 Years Based on Two Randomized Controlled Trials in China

Authors: Hudachuan Jiang, Pengfei Jin, Xiling Guo, Jiahong Zhu, Xue Wang, Peng Wan, Jingxuan Wan, Jingxian Liu, Jingxin Li, Fengcai Zhu

Journal: Vaccines (Basel)

PubMed ID: 38140219

Doi: 10.3390/vaccines11121815

Products & Services: Monoclonal Antibody Services

Host IPR channels are dispensable for rotavirus Ca signaling but critical for intercellular Ca waves that prime uninfected cells for rapid virus spread

Authors: Jacob L Perry, Francesca J Scribano, John T Gebert, Kristen A Engevik, Jenna M Ellis, Joseph M Hyser

Journal: MBio

PubMed ID: 38112482

Doi: 10.1128/mbio.02145-23

Products & Services: Gene Synthesis

A Chemical Strategy for the Degradation of the Main Protease of SARS-CoV‐2 in Cells

Authors: Xiaohong Sang, Juan Wang, Jiao Zhou, Yan Xu, Jing An, Arieh Warshel, Ziwei Huang

Journal: J Am Chem Soc

PubMed ID: 38064654

Doi: 10.1021/jacs.3c12678.

Products & Services: Codon Optimization

Manganese@Albumin Nanocomplex and Its Assembled Nanowire Activate TLR4-Dependent Signaling Cascades of Macrophages

Authors: Shuodan Huang, Yan Gao, Huiying Li, Ruoran Wang, Xiaomei Zhang, Xiaoyu Wang, Di Huang, Linxuan Zhang, Hélder A Santos, Zhenyu Yin, Bing Xia

Journal: Adv Mater

PubMed ID: 37994277

Doi: 10.1002/adma.202310979

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Multivalent nanobody-based sandwich enzyme-linked immunosorbent assay for sensitive detection of porcine reproductive and respiratory syndrome virus

Authors: Mingxia Sun, Yue Sun, Yongbo Yang, Man Zhao, Dan Cao, Minmin Zhang, Dasong Xia, Tao Wang, Yanfei Gao, Shanghui Wang, Haiwei Wang, Xuehui Cai, Tongqing An

Journal: Int J Biol Macromol

PubMed ID: 38143067

Doi: 10.1016/j.ijbiomac.2023.128896

Products & Services: Proteins, Expression, Isolation and Analysis

Discrimination of Disaccharide Isomers of Different Glycosidic Linkages Using a Modified MspA Nanopore

Authors: Shanyu Zhang , Zhenyuan Cao , Pingping Fan , Wen Sun , Yunqi Xiao , Panke Zhang , Yuqin Wang , Shuo Huang

Journal: Angew Chem Int Ed Engl .

PubMed ID: 38116834

Doi: 10.1002/anie.202316766

Products & Services: Gene Synthesis

Reproduction of Varroa destructor depends on well-timed host cell recapping and seasonal patterns

Authors: Martin Gabel, Ricarda Scheiner, Ingolf Steffan-Dewenter, Ralph Büchler

Journal: Sci Rep

PubMed ID: 38110489

Doi: 10.1038/s41598-023-49688-9

Products & Services: Proteins, Expression, Isolation and Analysis

Engineered Antiviral Sensor Targets Infected Mosquitoes

Authors: Elena Dalla Benetta, Adam J López-Denman, Hsing-Han Li, Reem A Masri, Daniel J Brogan, Michelle Bui, Ting Yang, Ming Li, Michael Dunn, Melissa J Klein, Sarah Jackson, Kyle Catalan, Kim R Blasdell, Priscilla Tng, Igor Antoshechkin, Luke S Alphey, Prasad N Paradkar, Omar S Akbari

Journal: CRISPR J

PubMed ID: 38108518

Doi: 10.1089/crispr.2023.0056

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Immunorecognition of Streptococcus mutans secreted proteins protects against caries by limiting tooth adhesion

Authors: Omer Bender, Jessica Khoury, Gal Hirsch, Evgeny Weinberg, Naor Sagy, Shani Buller, Shiri Lapides-Levy, Sigalit Blumer, Daniel Z Bar

Journal: J Dent

PubMed ID: 38101504

Doi: 10.1016/j.jdent.2023.104805

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular mechanism of CCDC106 regulating the p53-Mdm2/MdmX signaling axis

Authors: Ting Zhou, Zhiqiang Ke, Qianqian Ma, Jiani Xiang, Meng Gao, Yongqi Huang, Xiyao Cheng, Zhengding Su

Journal: Sci Rep

PubMed ID: 38081879

Doi: 10.1038/s41598-023-47808-z

Products & Services: Proteins, Expression, Isolation and Analysis

Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2

Authors: Xia Rao, Runchu Zhao, Zhou Tong, Shuxin Guo, Weiyu Peng, Kefang Liu, Shihua Li, Lili Wu, Jianyu Tong, Yan Chai, Pu Han, Feiran Wang, Peng Jia, Zhaohui Li, Xin Zhao, Dedong Li, Rong Zhang, Xue Zhang, Weiwei Zou, Weiwei Li, Qihui Wang, George Fu Gao, Yan Wu, Lianpan Dai, Feng Gao

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38109549

Doi: 10.1073/pnas.2314193120

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Localization confirms EnApiAP2 protein encoded by as a nuclear protein in

Authors: Weimin Cai, Qianqian Feng, Liyue Wang, Shijie Su, Zhaofeng Hou, Dandan Liu, Xilong Kang, Jinjun Xu, Zhiming Pan, Jianping Tao

Journal: Front Cell Infect Microbiol

PubMed ID: 38116134

Doi: 10.3389/fcimb.2023.1305727

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Effect of Nk-lysin peptides on bacterial growth, MIC, antimicrobial resistance, and viral activities

Authors: Haitham A Yacoub, Maged Mostafa Mahmoud, Ahmed M Al-Hejin, Turki S Abujamel, Shams Tabrez, Sherif Abd-Elmaksoud

Journal: Anim Biotechnol

PubMed ID: 38100547

Doi: 10.1080/10495398.2023.2290520

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Propagation of conformational instability in FK506-binding protein FKBP12

Authors: David M LeMaster, Qamar Bashir, Griselda Hernández

Journal: Biochim Biophys Acta Proteins Proteom

PubMed ID: 38142946

Doi: 10.1016/j.bbapap.2023.140990

Products & Services: Proteins, Expression, Isolation and Analysis

A bioengineered anti-VEGF protein with high affinity and high concentration for intravitreal treatment of wet age-related macular degeneration

Authors: Chengnan Huang, Yuelin Wang, Jinliang Huang, Huiqin Liu, Zhidong Chen, Yang Jiang, Youxin Chen, Feng Qian

Journal: Bioeng Transl Med

PubMed ID: 38435828

Doi: 10.1002/btm2.10632

Products & Services: Recombinant Proteins

MAT2A inhibition suppresses inflammation in -infected human gingival fibroblasts

Authors: Lishan Jiang, Jingwen Li, Kun Ji, Lang Lei, Houxuan Li

Journal: J Oral Microbiol

PubMed ID: 38130504

Doi: 10.1080/20002297.2023.2292375

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Identification of as a novel regulator of carfilzomib resistance in multiple myeloma

Authors: Jie Zhao, Xuantao Yang, Haixi Zhang, Xuezhong Gu

Journal: Oncol Res

PubMed ID: 38186567

Doi: 10.32604/or.2023.030770

Products & Services: Proteins, Expression, Isolation and Analysis

Engineering to produce -muconic acid from biomass aromatics

Authors: Avery C Vilbert, Wayne S Kontur, Derek Gille, Daniel R Noguera, Timothy J Donohue

Journal: Appl Environ Microbiol

PubMed ID: 38117061

Doi: 10.1128/aem.01660-23

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Repeated mRNA vaccination sequentially boosts SARS-CoV-2-specific CD8 T cells in persons with previous COVID-19

Authors: Emily S Ford, Koshlan Mayer-Blackwell, Lichen Jing, Kerry J Laing, Anton M Sholukh, Russell St Germain, Emily L Bossard, Hong Xie, Thomas H Pulliam, Saumya Jani, Stacy Selke, Carlissa J Burrow, Christopher L McClurkan, Anna Wald, Alexander L Greninger, Michael R Holbrook, Brett Eaton, Elizabeth Eudy, Michael Murphy, Elena Postnikova, Harlan S Robins, Rebecca Elyanow, Rachel M Gittelman, Matyas Ecsedi, Elise Wilcox, Aude G Chapuis, Andrew Fiore-Gartland, David M Koelle

Journal: Nat Immunol

PubMed ID: 38057617

Doi: 10.1038/s41590-023-01692-x

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Association of LOX gene G473A polymorphism with the occurrence of allergic rhinitis and efficacy of montelukast sodium in children

Authors: Xikun Yao, Yan Liu, Hong Jiao, Wenjie Ma, Minliang Chen

Journal: Cell Cycle

PubMed ID: 38009683

Doi: 10.1080/15384101.2023.2286802

Products & Services: Proteins, Expression, Isolation and Analysis

MscI restriction enzyme cooperating recombinase-aided isothermal amplification for the ultrasensitive and rapid detection of low-abundance EGFR mutations on microfluidic chip

Authors: Shiqi Xu, Xinjie Wang, Chengyuan Wu, Xueting Zhu, Xinyi Deng, Yue Wu, Ming Liu, Xingxu Huang, Lina Wu, He Huang

Journal: Biosens Bioelectron

PubMed ID: 38134625

Doi: 10.1016/j.bios.2023.115925

Products & Services: Proteins, Expression, Isolation and Analysis

A Replication-Competent Retroviral Vector Expressing the HERV-W Envelope Glycoprotein is a Potential Tool for Cancer Gene Therapy

Authors: Byoung Kwon Kang, Yong-Tae Jung

Journal: J Microbiol Biotechnol

PubMed ID: 38247210

Doi: 10.4014/jmb.2309.09022

Products & Services: Gene Synthesis

ACE2-Fc and DPP4-Fc decoy receptors against SARS-CoV-2 and MERS-CoV variants: a quick therapeutic option for current and future coronaviruses outbreaks

Authors: Mohamed A Alfaleh, Reem M Alsulaiman, Sarah A Almahboub, Leena Nezamuldeen, Ayat Zawawi, Najwa D Aljehani, Muhammad Yasir, Rwaa H Abdulal, Rami Alkhaldi, Assala Helal, Sawsan S Alamri, Jana Malki, Rowa Y Alhabbab, Turki S Abujamel, Nabil A Alhakamy, Aisha Alnami, Abdullah Algaissi, Mazen Hassanain, Anwar M Hashem

Journal: Antib Ther

PubMed ID: 38371953

Doi: 10.1093/abt/tbad030

Products & Services: Codon Optimization

Safinamide alleviates hyperalgesia via inhibiting hyperexcitability of DRG neurons in a mouse model of Parkinson's disease

Authors: Li-Ge Zhang, Jing Cheng, Meng-Qi An, Cheng-Jie Li, Li-Guo Dong, Jian-Min Wang, Chun-Feng Liu, Fen Wang, Cheng-Jie Mao

Journal: Behav Brain Res

PubMed ID: 38042302

Doi: 10.1016/j.bbr.2023.114787

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A nanobody inhibiting porcine reproductive and respiratory syndrome virus replication via blocking self-interaction of viral nucleocapsid protein

Authors: Hong Duan, Xu Chen, Ziwei Zhang, Zhijie Zhang, Zhihan Li, Xinjie Wang, Jiakai Zhao, Yuchen Nan, Baoyuan Liu, Angke Zhang, Yani Sun, Qin Zhao

Journal: J Virol

PubMed ID: 38084961

Doi: 10.1128/jvi.01319-23

Products & Services: Proteins, Expression, Isolation and Analysis

Novel role of peptidoglycan recognition protein 2 in activating NOD2-NFκB inflammatory axis in coronary artery disease

Authors: Pratitusti Basu, Apabrita Ayan Das, Khawer N Siddiqui, Prakas C Mondal, Arun Bandyopadhyay

Journal: Atherosclerosis

PubMed ID: 38277990

Doi: 10.1016/j.atherosclerosis.2023.117436

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Flagellar hook protein FlgE promotes macrophage activation and atherosclerosis by targeting ATP5B

Authors: Yuanyuan Li, Min Zhang, Yanmeng Li, Ying Shen, Xiaoping Wang, Xiaolu Li, Yiqiang Wang, Tao Yu, Jie Lv, Yan Qin

Journal: Atherosclerosis

PubMed ID: 38278062

Doi: 10.1016/j.atherosclerosis.2023.117429

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A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine

Authors: Wenming Liu , Hengchun Li , Bo Liu , Tianxing Lv , Chenchen Yang , Si Chen , Liqiang Feng , Liangxue Lai , Ziyuan Duan , Xinwen Chen , Pingchao Li , Suhua Guan , Ling Chen

Journal: Emerg Microbes Infect .

PubMed ID: 37401832

Doi: 10.1080/22221751.2023.2233643

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Influence of a D-enantiomeric peptide on the anticorrosion ability of titanium with different surface roughness against Streptococcus mutans biofilms

Authors: Dan Wang, Jian Yu, He Liu, Tian Zhang, Evan F Haney, Robert E W Hancock, Lin Peng, Ya Shen

Journal: J Dent

PubMed ID: 37944630

Doi: 10.1016/j.jdent.2023.104777

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Development of automated microfluidic immunoassays for the detection of SARS-CoV-2 antibodies and antigen

Authors: Linwood Johnson, Maggie L Bartlett, Francisco Ramirez, Christopher D Heger, Darci R Smith

Journal: J Immunol Methods

PubMed ID: 38040191

Doi: 10.1016/j.jim.2023.113586

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A Novel Interaction Between RAD23A/B and Y-family DNA Polymerases

Authors: Nicholas W Ashton, Nancy Jaiswal, Natália Cestari Moreno, Irina V Semenova, Dana A D'Orlando, Marcela Teatin Latancia, Justyna McIntyre, Roger Woodgate, Irina Bezsonova

Journal: J Mol Biol

PubMed ID: 37935254

Doi: 10.1016/j.jmb.2023.168353

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Extramedullary hematopoiesis contributes to enhanced erythropoiesis during pregnancy via TGF-β signaling

Authors: Yao Fu, Zhengjuan Li, Wen Lin, Jingxin Yao, Xiang Jiang, Qun Shu, Xiaoyuan Mao, Jiaoqin Tu, Xinyuan Liang, Liping Li

Journal: Front Immunol

PubMed ID: 38045690

Doi: 10.3389/fimmu.2023.1295717

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2-Hydroxyglutarate modulates histone methylation at specific loci and alters gene expression via Rph1 inhibition

Authors: Marios Gavriil, Marco Proietto, Nicole Paczia, Aurelien Ginolhac, Rashi Halder, Elena Valceschini, Thomas Sauter, Carole L Linster, Lasse Sinkkonen

Journal: Life Sci Alliance

PubMed ID: 38011998

Doi: 10.26508/lsa.202302333

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Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin

Authors: Qi Tang, Hassan H Fakih, Mohammad Zain Ui Abideen, Samuel R Hildebrand, Khashayar Afshari, Katherine Y Gross, Jacquelyn Sousa, Allison S Maebius, Christina Bartholdy, Pia Pernille Søgaard, Malene Jackerott, Vignesh Hariharan, Ashley Summers, Xueli Fan, Ken Okamura, Kathryn R Monopoli, David A Cooper, Dimas Echeverria, Brianna Bramato, Nicholas McHugh, Raymond C Furgal, Karen Dresser, Sarah J Winter, Annabelle Biscans, Jane Chuprin, Nazgol-Sadat Haddadi, Shany Sherman, Ümmügülsüm Yıldız-Altay, Mehdi Rashighi, Jillian M Richmond, Claire Bouix-Peter, Carine Blanchard, Adam Clauss, Julia F Alterman, Anastasia Khvorova, John E Harris

Journal: Nat Commun

PubMed ID: 37925520

Doi: 10.1038/s41467-023-42714-4

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Biochemical and cellular insights into the Baz2B protein, a non-catalytic subunit of the chromatin remodeling complex

Authors: Matthias Breindl, Dominika Spitzer, Rūta Gerasimaitė, Visvaldas Kairys, Thomas Schubert, Ramona Henfling, Uwe Schwartz, Gražvydas Lukinavičius, Laura Manelytė

Journal: Nucleic Acids Res

PubMed ID: 38000389

Doi: 10.1093/nar/gkad1096

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A dual role of RBM42 in modulating splicing and translation of CDKN1A/p21 during DNA damage response

Authors: Bella M Ben-Oz, Feras E Machour, Marian Nicola, Amir Argoetti, Galia Polyak, Rawad Hanna, Oded Kleifeld, Yael Mandel-Gutfreund, Nabieh Ayoub

Journal: Nat Commun

PubMed ID: 37993446

Doi: 10.1038/s41467-023-43495-6

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Linear motif specificity in signaling through p38α and ERK2 mitogen-activated protein kinases

Authors: Jaylissa Torres Robles, Hua Jane Lou, Guangda Shi, Pauline Lining Pan, Benjamin E Turk

Journal: Proc Natl Acad Sci U S A

PubMed ID: 37988460

Doi: 10.1073/pnas.2316599120

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Expression and characterization of novel chimeric endolysin CHAPk-SH3bk against biofilm-forming methicillin-resistant Staphylococcus aureus

Authors: Manisha Behera, Gagandeep Singh, Ashutosh Vats, Mayank Roshan, Devika Gautam, Chanchal Rana, Rajesh Kumar Kesharwani, Sachinandan De, Soma M Ghorai

Journal: Int J Biol Macromol

PubMed ID: 37944719

Doi: 10.1016/j.ijbiomac.2023.127969

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A sensitive luciferase reporter assay for the detection of infectious African swine fever virus

Authors: Kemal Mehinagic, Matthias Liniger, Maksym Samoilenko, Nick Soltermann, Markus Gerber, Nicolas Ruggli

Journal: J Virol Methods

PubMed ID: 37989458

Doi: 10.1016/j.jviromet.2023.114854

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Engineering self-deliverable ribonucleoproteins for genome editing in the brain

Authors: Kai Chen, Elizabeth C Stahl, Min Hyung Kang, Bryant Xu, Ryan Allen, Marena Trinidad, Jennifer A Doudna

Journal: biorxiv

PubMed ID: 38014180

Doi: 10.1101/2023.11.15.567251

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Insights into Molecular Diversity within the FET Family: Unraveling Phase Separation of the N-Terminal Low Complexity Domain from RNA-Binding Protein EWS

Authors: Courtney N Johnson, Kandarp A Sojitra, Erich J Sohn, Alma K Moreno-Romero, Antoine Baudin, Xiaoping Xu, Jeetain Mittal, David S Libich

Journal: biorxiv

PubMed ID: 37961424

Doi: 10.1101/2023.10.27.564484

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Changes in intestinal flora of mice induced by rEgP29 epitope peptide vaccines

Authors: Tingting Zhang, Yongxue Lv, Yinqi Zhao, Jihui Yang, Bingshuo Qian, Yazhou Zhu, Wei Zhao, Mingxing Zhu

Journal: Immun Inflamm Dis

PubMed ID: 38018604

Doi: 10.1002/iid3.1082

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AR/RKIP pathway mediates the inhibitory effects of icariin on renal fibrosis and endothelial-to-mesenchymal transition in type 2 diabetic nephropathy

Authors: Wenhui Yao, Rongpin Tao, Yue Xu, Zhe-Sheng Chen, Xuansheng Ding, Lisheng Wan

Journal: J Ethnopharmacol

PubMed ID: 37977422

Doi: 10.1016/j.jep.2023.117414

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Application of machine learning algorithms to construct and validate a prediction model for coronary heart disease risk in patients with periodontitis: a population-based study

Authors: Yicheng Wang, Binghang Ni, Yuan Xiao, Yichang Lin, Yu Jiang, Yan Zhang

Journal: Front Cardiovasc Med

PubMed ID: 38094122

Doi: 10.3389/fcvm.2023.1296405

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Mutations in yeast Pcf11, a conserved protein essential for mRNA 3' end processing and transcription termination, elicit the Environmental Stress Response

Authors: Joel H Graber, Derick Hoskinson, Huiyun Liu, Katarzyna Kaczmarek Michaels, Peter S Benson, Nathaniel J Maki, Christian L Wilson, Caleb McGrath, Franco Puleo, Erika Pearson, Jason N Kuehner, Claire Moore

Journal: Genetics

PubMed ID: 37967370

Doi: 10.1093/genetics/iyad199

Products & Services: Proteins, Expression, Isolation and Analysis

Reduction of oligomer size modulates the competition between cluster formation and phase separation of the tumor suppressor SPOP

Authors: Nafiseh Sabri, Matthew J Cuneo, Melissa R Marzahn, Jihun Lee, Jill J Bouchard, Ömer Güllülü, Sivaraja Vaithiyalingam, Madeleine B Borgia, Jeremy Schmit, Tanja Mittag

Journal: J Biol Chem

PubMed ID: 37926283

Doi: 10.1016/j.jbc.2023.105427

Products & Services: Proteins, Expression, Isolation and Analysis

SARS-CoV-2 ORF7a blocked autophagy flux by intervening in the fusion between autophagosome and lysosome to promote viral infection and pathogenesis

Authors: Shun Li, Xiaobo Li, Haowei Liang, Kuike Yu, Jingbo Zhai, Mengzhou Xue, Zhuojing Luo, Chunfu Zheng, Hao Zhang

Journal: J Med Virol

PubMed ID: 37916857

Doi: 10.1002/jmv.29200

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RING-type E3 ligase BnaJUL1 ubiquitinates and degrades BnaTBCC1 to regulate drought tolerance in Brassica napus L

Authors: Jin Hu, Mudan Luo, Xianming Zhou, Zhaoyang Wang, Li Yan, Dengfeng Hong, Guangsheng Yang, Xiaohui Zhang

Journal: Plant Cell Environ

PubMed ID: 37984059

Doi: 10.1111/pce.14770

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TRIM22 facilitates autophagosome-lysosome fusion by mediating the association of GABARAPs and PLEKHM1

Authors: Hansol Heo, Hyungsun Park, Myung Shin Lee, Jongyoon Kim, Juyeong Kim, Soon-Young Jung, Sun Kyeon Kim, Seongju Lee, Jaerak Chang

Journal: Autophagy

PubMed ID: 38009729

Doi: 10.1080/15548627.2023.2287925

Products & Services: Proteins, Expression, Isolation and Analysis

Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans

Authors: Alexandra V Vylegzhanina, Ivan A Bespalov, Ksenia A Novototskaya-Vlasova, Brandon M Hall, Anatoli S Gleiberman, Han Yu, Olga V Leontieva, Katerina I Leonova, Oleg V Kurnasov, Andrei L Osterman, Grace K Dy, Alexey A Komissarov, Elena Vasilieva, Jeff Gehlhausen, Akiko Iwasaki, Christine B Ambrosone, Takemasa Tsuji, Junko Matsuzaki, Kunle Odunsi, Ekaterina L Andrianova, Andrei V Gudkov

Journal: Cancer Res Commun

PubMed ID: 37870410

Doi: 10.1158/2767-9764.CRC-23-0289

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Increasing insight in the value of repetitive COVID-19 vaccination in patients with haematological malignancies in the Omicron era

Authors: Ulrike Bacher, Evgenii Shumilov, Thomas Pabst

Journal: Br J Haematol

PubMed ID: 37984996

Doi: 10.1111/bjh.19221

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OsALB3 Is Required for Chloroplast Development by Promoting the Accumulation of Light-Harvesting Chlorophyll-Binding Proteins in Rice

Authors: Chao Zhang, Xinchen Mao, Xiaoxiao Feng, Yali Sun, Zirui Wang, Jiaqi Tang, Hengxiu Yu

Journal: Plants (Basel)

PubMed ID: 38068638

Doi: 10.3390/plants12234003

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Structure and functional divergence of PIP peptide family revealed by functional studies on PIP1 and PIP2 in

Authors: Xiao-Song Yu, Hong-Run Wang, Fei-Fan Lei, Rui-Qi Li, Hui-Peng Yao, Jin-Bo Shen, Noor-Ul Ain, Yi Cai

Journal: Front Plant Sci

PubMed ID: 38078092

Doi: 10.3389/fpls.2023.1208549

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Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia

Authors: Gianna M Branella, Jasmine Y Lee, Jennifer Okalova, Kiran K Parwani, Jordan S Alexander, Raquel F Arthuzo, Andrew Fedanov, Bing Yu, David McCarty, Harrison C Brown, Shanmuganathan Chandrakasan, Brian G Petrich, Christopher B Doering, H Trent Spencer

Journal: Front Immunol

PubMed ID: 38022523

Doi: 10.3389/fimmu.2023.1294555

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Substance P Increases STAT6-Mediated Transcription Activation of Lymphocyte Cytosolic Protein 2 to Sustain M2 Macrophage Predominance in Pediatric Asthma

Authors: Miao Li, Xiao Zhong, Wenting Xu

Journal: Am J Pathol

PubMed ID: 37995836

Doi: 10.1016/j.ajpath.2023.11.003

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Juvenile hormone induces reproduction via miR-1175-3p in the red imported fire ant, Solenopsis invicta

Authors: Jie Chen, Ziying Guan, Yunjie Ma, Qingxing Shi, Ting Chen, Muhammad Irfan Waris, Lihua Lyu, Yongyue Lu, Guojun Qi

Journal: Insect Sci

PubMed ID: 37933419

Doi: 10.1111/1744-7917.13291

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Biophysical and biochemical characterization of the thioredoxin system from Colwellia psychrerythraea

Authors: Naheda Sahtout, David A R Sanders

Journal: Proteins

PubMed ID: 37909486

Doi: 10.1002/prot.26627

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Mesenchymal stem cells attenuate systemic lupus erythematosus by inhibiting NLRP3 inflammasome activation through Pim-1 kinase

Authors: Honghong Yu, Qi Li, Huimin Zhu, Chang Liu, Weiwei Chen, Lingyun Sun

Journal: Int Immunopharmacol

PubMed ID: 37992447

Doi: 10.1016/j.intimp.2023.111256

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Human leukocyte antigen HLA-DR-expressing fibroblast-like synoviocytes are inducible antigen presenting cells that present autoantigens in Lyme arthritis

Authors: Joseph R Rouse, Rebecca Danner, Amanda Wahhab, Michaela Pereckas, Mecaila E McClune, Allen C Steere, Klemen Strle, Brandon L Jutras, Robert B Lochhead

Journal: biorxiv

PubMed ID: 38045407

Doi: 10.1101/2023.11.21.568066

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NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis

Authors: Yves Dondelinger, Dario Priem, Jon Huyghe, Tom Delanghe, Peter Vandenabeele, Mathieu J M Bertrand

Journal: Cell Death Dis

PubMed ID: 37980412

Doi: 10.1038/s41419-023-06284-z

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