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NRF2 mutation enhances the immune escape of hepatocellular carcinoma by reducing STING activation

Authors: Cheng Li, Gang Liang, Ke Yan, Yongheng Wang

Journal: Biochem Biophys Res Commun

PubMed ID: 38271834

Doi: 10.1016/j.bbrc.2024.149536

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Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria

Authors: Sabine Poerschke, Silke Oeljeklaus, Luis Daniel Cruz-Zaragoza, Alexander Schenzielorz, Drishan Dahal, Hauke Sven Hillen, Hirak Das, Laura Sophie Kremer, Anusha Valpadashi, Mirjam Breuer, Johannes Sattmann, Ricarda Richter-Dennerlein, Bettina Warscheid, Sven Dennerlein, Peter Rehling

Journal: Cell

PubMed ID: 38199007

Doi: 10.1016/j.molcel.2023.12.013

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Quaternization drives spleen-to-lung tropism conversion for mRNA-loaded lipid-like nanoassemblies

Authors: Yixuan Huang , Jiacai Wu , Sanpeng Li , Zhen Liu , Zhenghua Li , Boping Zhou , Bin Li

Journal: Theranostics

PubMed ID: 38169552

Doi: 10.7150/thno.90071

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Oat Peptides Alleviate Dextran Sulfate Sodium Salt-Induced Colitis by Maintaining the Intestinal Barrier and Modulating the Keap1-Nrf2 Axis

Authors: Zhong-Hao Ji, Wen-Yin Xie , Pei-Sen Zhao , Hong-Yu Wu , Wen-Zhi Ren , Jin-Ping Hu , Wei Gao , Bao Yuan

Journal: Nutrients .

PubMed ID: 38140314

Doi: 10.3390/nu15245055

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Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function

Authors: Leonardo A Parra-Rivas , Kayalvizhi Madhivanan , Brent D Aulston , Lina Wang , Dube Dheeraj Prakashchand , Nicholas P Boyer , Veronica M Saia-Cereda , Kristen Branes-Guerrero , Donald P Pizzo , Pritha Bagchi , V S Sundar , Yong Tang , Utpal Das , David A Scott , Padmini Rangamani , Yuki Ogawa , Subhojit Roy

Journal: Neuron .

PubMed ID: 38128479

Doi: 10.1016/j.neuron.2023.11.020

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Staphylococcus aureus functional amyloids catalyze degradation of β-lactam antibiotics

Authors: Elad Arad , Kasper B Pedersen , Orit Malka, Sisira Mambram Kunnath , Nimrod Golan , Polina Aibinder , Birgit Schiøtt , Hanna Rapaport, Meytal Landau , Raz Jelinek

Journal: Nat Commun .

PubMed ID: 38081813

Doi: s41467-023-43624-1

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Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate

Authors: Liyang Du , Qinwei Zhu & Zhonghui Lin

Journal: The EMBO Journal

Doi: 10.1038/s44318-023-00017-w

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Structural dynamics of the CROPs domain control stability and toxicity of Paeniclostridium sordellii lethal toxin

Authors: Yao Zhou, Xiechao Zhan , Jianhua Luo, Diyin Li , Ruoyu Zhou , Jiahao Zhang , Zhenrui Pan , Yuanyuan Zhang , Tianhui Jia , Xiaofeng Zhang , Yanyan Li , Liang Tao

Journal: Nat Commun .

PubMed ID: 38114525

Doi: 10.1038/s41467-023-44169-z

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Structural analysis and functional evaluation of the disordered ß–hexosyltransferase region from Hamamotoa (Sporobolomyces) singularis

Authors: Suzanne F Dagher, Asmita Vaishnav, Christopher B Stanley, Flora Meilleur, Brian F P Edwards , José M Bruno-Bárcena

Journal: Front Bioeng Biotechnol

PubMed ID: 38162180

Doi: 10.3389/fbioe.2023.1291245

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Engineering minimal tissue inhibitors of metalloproteinase targeting MMPs via gene shuffling and yeast surface display

Authors: Arman Hosseini, Sachin Kumar, Kyle Hedin, Maryam Raeeszadeh-Sarmazdeh

Journal: Protein Sci

PubMed ID: 37807423

Doi: 10.1002/pro.4795

Products & Services: Proteins, Expression, Isolation and Analysis

A functional and structural comparative analysis of Large Tumor Antigens reveals evolution of different importin α-dependent nuclear localization signals

Authors: Emily M Cross, Nasim Akbari, Hanieh Ghassabian, Mikayla Hoad, Silvia Pavan, Daryl Ariawan, Camilla M Donnelly, Enrico Lavezzo, Gayle F Petersen, Jade K Forwood, Gualtiero Alvisi

Journal: Protein Sci

PubMed ID: 38108201

Doi: 10.1002/pro.4876

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Choosing the right mouse model: comparison of humanized NSG and NBSGW mice for in vivo HSC gene therapy

Authors: Seunga Choo, Carl B Wolf, Heather M Mack, Mitchell J Egan, Hans-Peter Kiem, Stefan Radtke

Journal: Blood Adv

PubMed ID: 38113461

Doi: 10.1182/bloodadvances.2023011371

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A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity

Authors: Solange Moréra, Armelle Vigouroux, Magali Aumont-Nicaise, Mohammed Ahmar, Thibault Meyer, Abbas El Sahili, Grégory Deicsics, Almudena González-Mula, Sizhe Li, Jeanne Doré, Serena Siragu, Pierre Legrand, Camille Penot, François Andrè, Denis Faure, Laurent Soulère, Yves Queneau, Ludovic Vial

Journal: Biochem J

PubMed ID: 38058289

Doi: 10.1042/BCJ20230273

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Secretory carrier-associated membrane protein 5 regulates cell-surface targeting of T-type calcium channels

Authors: Emilio R Mustafá, Konstantin Weiß, Norbert Weiss

Journal: Channels (Austin)

PubMed ID: 37389974

Doi: 10.1080/19336950.2023.2230776

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Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family

Authors: Benoit Arragain, Martin Pelosse, Albert Thompson, Stephen Cusack

Journal: Nat Commun

PubMed ID: 38066000

Doi: 10.1038/s41467-023-44044-x

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N6-methyladenosine methylation analysis of long noncoding RNAs and mRNAs in 5-FU-resistant colon cancer cells

Authors: Jie Lai, Zhiyong Zhou, Kan Hu, HongLong Yu, Xingyao Su, Xiaoqiang Niu, Huizi Li, Shengxun Mao

Journal: Epigenetics

PubMed ID: 38145548

Doi: 10.1080/15592294.2023.2298058

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Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma: a first-in-human study

Authors: Yunlin Zhang, Ruchi P Patel, Ki Hyun Kim, Hyungwoo Cho, Jae-Cheol Jo, Seong Hyun Jeong, Sung Yong Oh, Yoon Seok Choi, Sung Hyun Kim, Ji Hyun Lee, Mathew Angelos, Puneeth Guruprasad, Ivan Cohen, Ositadimma Ugwuanyi, Yong Gu Lee, Raymone Pajarillo, Jong Hyun Cho, Alberto Carturan, Luca Paruzzo, Guido Ghilardi, Michael Wang, Soohwan Kim, Sung-Min Kim, Hyun-Jong Lee, Ji-Ho Park, Leiguang Cui, Tae Bum Lee, In-Sik Hwang, Young-Ha Lee, Yong-Jun Lee, Patrizia Porazzi, Dongfang Liu, Yoon Lee, Jong-Hoon Kim, Jong-Seo Lee, Dok Hyun Yoon, Junho Chung, Marco Ruella

Journal: Mol Cancer

PubMed ID: 38066564

Doi: 10.1186/s12943-023-01886-9

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Plasma circRNA HIPK2 as a putative biomarker for the diagnosis and prediction of therapeutic effects in major depressive disorder

Authors: Xiaoyu Yu, Zhenyu Fan, Tingting Yang, Heng Li, Yachen Shi, Long Ye, Rongrong Huang

Journal: Clin Chim Acta

PubMed ID: 38065380

Doi: 10.1016/j.cca.2023.117694

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A biosynthetic network for protoberberine production in

Authors: Linrui Wu, Binxin Zhao, Zixin Deng, Bin Wang, Yi Yu

Journal: Hortic Res

PubMed ID: 38282690

Doi: 10.1093/hr/uhad259

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DPY30 promotes colorectal carcinoma metastasis by upregulating ZEB1 transcriptional expression

Authors: Chun-Ying Luo, Wei-Chao Su, Hai-Feng Jiang, Ling-Tao Luo, Dong-Yan Shen, Guo-Qiang Su

Journal: Cancer Cell Int

PubMed ID: 38115111

Doi: 10.1186/s12935-023-03126-y

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Recombinant bovine FGF1 promotes muscle satellite cells mitochondrial fission and proliferation in serum-free conditions

Authors: Qingying Liu, Lianghua Xie, Wei Chen

Journal: Food Res Int

PubMed ID: 38129067

Doi: 10.1016/j.foodres.2023.113794

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Dachsous and Fat coordinately repress the Dachs–Dlish–Approximated complex to control growth

Authors: Hitoshi Matakatsu , Richard G Fehon

Journal: J Cell Biol

PubMed ID: 39373700

Doi: 10.1083/jcb.202406119

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Intranasal mask for protecting the respiratory tract against viral aerosols

Authors: Xiaoming Hu, Shuang Wang, Shaotong Fu, Meng Qin, Chengliang Lyu, Zhaowen Ding, Yan Wang, Yishu Wang, Dongshu Wang, Li Zhu, Tao Jiang, Jing Sun, Hui Ding, Jie Wu, Lingqian Chang, Yimin Cui, Xiaocong Pang, Youchun Wang, Weijin Huang, Peidong Yang, Limin Wang, Guanghui Ma, Wei Wei

Journal: Nat Commun

PubMed ID: 38110357

Doi: 10.1038/s41467-023-44134-w

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Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs

Authors: Krystal C Johnson, Audrius Kilikevicius, Cristina Hofman, Jiaxin Hu, Yang Liu, Selina Aguilar, Jon Graswich, Yi Han, Tao Wang, Jill M Westcott, Rolf A Brekken, Lan Peng, Georgios Karagkounis, David R Corey

Journal: Nucleic Acids Res

PubMed ID: 38109320

Doi: 10.1093/nar/gkad1155

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Electrostatic-Dominated Conformational Fluctuations and Transition States of Phase Separation in Charge-Balanced Protein Polymer

Authors: Sougat Das, Tithi Basu, Saptarshi Majumdar

Journal: ACS Macro Lett

PubMed ID: 38109356

Doi: 10.1021/acsmacrolett.3c00625

Products & Services: Peptide Synthesis

Sensitive Blood-Based Detection of HIV-1 and Mycobacterium tuberculosis Peptides for Disease Diagnosis by Immuno-Affinity Liquid Chromatography-Tandem Mass Spectrometry: A Method Development and Proof-of-Concept Study

Authors: Lin Li, Christopher J Lyon, Sylvia M LaCourse, Wenshu Zheng, Joshua Stern, Jaclyn N Escudero, Wilfred Bundi Murithi, Lilian Njagi, Grace John-Stewart, Thomas R Hawn, Videlis Nduba, Wael Abdelgaliel, Thomas Tombler, David Horne, Li Jiang, Tony Y Hu

Journal: Clin Chem

PubMed ID: 37956323

Doi: 10.1093/clinchem/hvad173

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Novel SOX10 indel mutations drive schwannomas through impaired transactivation of myelination gene programs

Authors: Erik A Williams, Ajay Ravindranathan, Rohit Gupta, Nicholas O Stevers, Abigail K Suwala, Chibo Hong, Somang Kim, Jimmy Bo Yuan, Jasper Wu, Jairo Barreto, Calixto-Hope G Lucas, Emily Chan, Melike Pekmezci, Philip E LeBoit, Thaddeus Mully, Arie Perry, Andrew Bollen, Jessica Van Ziffle, W Patrick Devine, Alyssa T Reddy, Nalin Gupta, Kristen M Basnet, Robert J B Macaulay, Patrick Malafronte, Han Lee, William H Yong, Kevin Jon Williams, Tareq A Juratli, Douglas A Mata, Richard S P Huang, Matthew C Hiemenz, Dean C Pavlick, Garrett M Frampton, Tyler Janovitz, Jeffrey S Ross, Susan M Chang, Mitchel S Berger, Line Jacques, Jun S Song, Joseph F Costello, David A Solomon

Journal: Neuro Oncol

PubMed ID: 37436963

Doi: 10.1093/neuonc/noad121

Products & Services: Proteins, Expression, Isolation and Analysis

Phage Tail Fiber Protein as a Specific Probe for Recognition of Shiga Toxin-Producing O91, O103, and O111

Authors: Yibao Chen, Lulu Li, Xiaotian Wei, Ming Hu, Xiaonan Zhao, Qing Zhang, Yanbo Luo, Min Zhao, Zhengjie Liu, Yumei Cai, Yuqing Liu

Journal: Anal Chem

PubMed ID: 38053255

Doi: 10.1021/acs.analchem.3c03370

Products & Services: Molecular Biology Reagents

The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways

Authors: Rayene Berkane, Hung Ho-Xuan, Marius Glogger, Pablo Sanz-Martinez, Lorène Brunello, Tristan Glaesner, Santosh Kumar Kuncha, Katharina Holzhüter, Sara Cano-Franco, Viviana Buonomo, Paloma Cabrerizo-Poveda, Ashwin Balakrishnan, Georg Tascher, Koraljka Husnjak, Thomas Juretschke, Mohit Misra, Alexis González, Volker Dötsch, Paolo Grumati, Mike Heilemann, Alexandra Stolz

Journal: Nat Commun

PubMed ID: 38102139

Doi: 10.1038/s41467-023-44101-5

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Ubiquitin-specific protease 22 promotes tumorigenesis and progression by an FKBP12/mTORC1/autophagy positive feedback loop in hepatocellular carcinoma

Authors: Qianwei Ye, Wei Zhou, Shengjun Xu, Qingyang Que, Qifan Zhan, Lincheng Zhang, Shusen Zheng, Sunbin Ling, Xiao Xu

Journal: MedComm (2020)

PubMed ID: 38045832

Doi: 10.1002/mco2.439

Products & Services: Proteins, Expression, Isolation and Analysis

Authors: Yunxiang Zhao, Jiali Qin, Jingshuai Sun, Jian He, Yanmei Sun, Renqiang Yuan, Zhili Li

Journal: Theriogenology

PubMed ID: 38150851

Doi: 10.1016/j.theriogenology.2023.11.028

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Addressing the Binding Mechanism of the Meprin and TRAF-C Homology Domain of the Speckle-Type POZ Protein Using Protein Engineering

Authors: Awa Diop, Paola Pietrangeli, Valeria Pennacchietti, Livia Pagano, Angelo Toto, Mariana Di Felice, Sara Di Matteo, Lucia Marcocci, Francesca Malagrinò, Stefano Gianni

Journal: Int J Mol Sci

PubMed ID: 38139193

Doi: 10.3390/ijms242417364

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Combinatorial design of ionizable lipid nanoparticles for muscle-selective mRNA delivery with minimized off-target effects

Authors: Jingan Chen, Yue Xu, Muye Zhou, Shufen Xu, Andrew James Varley, Alex Golubovic, Rick Xing Ze Lu, Kevin Chang Wang, Mina Yeganeh, Daniel Vosoughi, Bowen Li

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38060560

Doi: 10.1073/pnas.2309472120

Products & Services: Molecular Biology Reagents

The role of CE16 exo-deacetylases in hemicellulolytic enzyme mixtures revealed by the biochemical and structural study of the novel TtCE16B esterase

Authors: Christina Pentari, Anastasia Zerva, Christos Kosinas, Panagiota Karampa, Vladimír Puchart, Maria Dimarogona, Evangelos Topakas

Journal: Carbohydr Polym

PubMed ID: 38171682

Doi: 10.1016/j.carbpol.2023.121667

Products & Services: Molecular Biology Reagents

A novel biomarker of MMP-cleaved cartilage intermediate layer protein-1 is elevated in patients with rheumatoid arthritis, ankylosing spondylitis and osteoarthritis

Authors: Helena Port, Cecilie Møller Hausgaard, Yi He, Walter P Maksymowych, Stephanie Wichuk, Dovile Sinkeviciute, Anne-Christine Bay-Jensen, Signe Holm Nielsen

Journal: Sci Rep

PubMed ID: 38066013

Doi: 10.1038/s41598-023-48787-x

Products & Services: Proteins, Expression, Isolation and Analysis

Rapid detection of in sputum using CRISPR-Cas12b combined with cross-priming amplification in a single reaction

Authors: Lijun Peng, Tingting Fang, Qingshan Cai, Hao Li, Huanyu Li, Haiqiong Sun, Mingzhi Zhu, Lingshan Dai, Yanqin Shao, Long Cai

Journal: J Clin Microbiol

PubMed ID: 38112450

Doi: 10.1128/jcm.00923-23

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Development of a double-antibody sandwich enzyme-linked immunosorbent assay for rapid detection of VZV

Authors: Aiping Wang, Na Liu, Jianguo Zhao, Yan Niu, Yumei Chen, Jingming Zhou, Enping Liu, Gaiping Zhang

Journal: J Virol Methods

PubMed ID: 38154579

Doi: 10.1016/j.jviromet.2023.114874

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Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents

Authors: Jaime S Rosa Duque, Samuel M S Cheng, Carolyn A Cohen, Daniel Leung, Xiwei Wang, Xiaofeng Mu, Yuet Chung, Tsun Ming Lau, Manni Wang, Wenyue Zhang, Yanmei Zhang, Howard H W Wong, Leo C H Tsang, Sara Chaothai, Tsz Chun Kwan, John K C Li, Karl C K Chan, Leo L H Luk, Jenson C H Ho, Wing Yan Li, Amos M T Lee, Jennifer H Y Lam, Sau Man Chan, Wilfred H S Wong, Issan Y S Tam, Masashi Mori, Sophie A Valkenburg, Malik Peiris, Wenwei Tu, Yu Lung Lau

Journal: World J Pediatr

PubMed ID: 38085470

Doi: 10.1007/s12519-023-00764-0

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Intracellular cholesterol visualization in brain tissue using D4H

Authors: Sherida M de Leeuw, Tal Nuriel

Journal: STAR Protoc

PubMed ID: 38100357

Doi: 10.1016/j.xpro.2023.102779

Products & Services: Recombinant Proteins

Molecular Characterization of Tick-borne Pathogens in Bactrian Camels and Ticks from Gansu Province, China

Authors: Hong-Xi Zhao, Xiao-Qing Zan, Jin-Zhong Tao, Xin-Gang Dan

Journal: Acta Parasitol

PubMed ID: 38087038

Doi: 10.1007/s11686-023-00752-4

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Purification of Human Cytoplasmic Actins From

Authors: Brian K Haarer, David C Amberg, Jessica L Henty-Ridilla

Journal: Bio Protoc

PubMed ID: 38094253

Doi: 10.21769/BioProtoc.4894

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Efficacy of cyclobutrifluram in controlling Fusarium crown rot of wheat and resistance risk of three Fusarium species to cyclobutrifluram

Authors: Haiyan Sun, Shiyan Cai, Yuanyu Deng, Shulin Cao, Xiaoyue Yang, Yanteng Lu, Wei Li, Huaigu Chen

Journal: Pestic Biochem Physiol

PubMed ID: 38225078

Doi: 10.1016/j.pestbp.2023.105723

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Shenqi Fuzheng injection restores the sensitivity to gefitinib in non-small cell lung cancer by inhibiting the IL-22 STAT3 AKT pathway

Authors: Jiali Wang , Xianhai He , Zhirong Jia , Aiwen Yan , Kang Xiao , Shuo Liu , Mengjun Hou , Yaling Long , Xuansheng Ding

Journal: Pharm Biol .

PubMed ID: 38100532

Doi: 10.1080/13880209.2023.2292266

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A KDPG sensor RccR governs Pseudomonas aeruginosa carbon metabolism and aminoglycoside antibiotic tolerance

Authors: Yujue Wang , Zhipeng Wang , Weizhong Chen , Ze-Hui Ren , Hui Gao , Jiani Dai , Guan-Zheng Luo , Zhaowei Wu , Quanjiang Ji

Journal: Nucleic Acids Res .

PubMed ID: 38096062

Doi: 10.1093/nar/gkad1201

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Synthetic High-Density Lipoprotein-Based Nanomedicine to Silence SOCS1 in Tumor Microenvironment and Trigger Antitumor Immunity against Glioma

Authors: Chunrong Yang , Yujie Li , Yuchen Yang , Qiankun Ni , Zeyu Zhang , Yi Chai , Jinghong Li

Journal: Angew Chem Int Ed Engl .

PubMed ID: 37847126

Doi: 10.1002/anie.202312603

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Structure and mechanism of a eukaryotic ceramide synthase complex

Authors: Tian Xie , Qi Fang , Zike Zhang , Yanfei Wang , Feitong Dong , Xin Gong

Journal: EMBO J .

PubMed ID: 37953642

Doi: 10.15252/embj.2023114889

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Biguanide chitosan microneedles with cell-free DNA scavenging ability for psoriasis therapy

Authors: Zihao Liu , Yu Wang , Yuhan Zhang , Liufu Hu , Bozhi Chen , Yang Li , Xindong Guo , Bingran Yu , Fu-Jian Xu

Journal: Bioactive Materials

Doi: 10.1016/j.bioactmat.2023.11.015

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The global transcription regulator XooClp governs Type IV pili system mediated bacterial virulence by directly binding to their promoters to coordinate virulence associated functions

Authors: Raj Kumar Verma, Parimala Gondu, Tirthankar Saha, Subhadeep Chatterjee

Journal: Mol Plant Microbe Interact

PubMed ID: 38105438

Doi: 10.1094/MPMI-07-23-0100-R

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Mucosal SARS-CoV-2 vaccination of rodents elicits superior systemic T central memory function and cross-neutralising antibodies against variants of concern

Authors: Aled O'Neill, Chinmay Kumar Mantri, Chee Wah Tan, Wilfried A A Saron, Santhosh Kambaiah Nagaraj, Monica Palanichamy Kala, Christy Margarat Joy, Abhay P S Rathore, Shashank Tripathi, Lin-Fa Wang, Ashley L St John

Journal: EBioMedicine

PubMed ID: 38113758

Doi: 10.1016/j.ebiom.2023.104924

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Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD

Authors: Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca, Shaohong Isaac Peng, Kevin Talbot, Ho Yin Edwin Chan

Journal: Nat Commun

PubMed ID: 38110419

Doi: 10.1038/s41467-023-44215-w

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RIF1 regulates early replication timing in murine B cells

Authors: Daniel Malzl, Mihaela Peycheva, Ali Rahjouei, Stefano Gnan, Kyle N Klein, Mariia Nazarova, Ursula E Schoeberl, David M Gilbert, Sara C B Buonomo, Michela Di Virgilio, Tobias Neumann, Rushad Pavri

Journal: Nat Commun

PubMed ID: 38081811

Doi: 10.1038/s41467-023-43778-y

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Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

Authors: Se Eun Kim, So Hee Park, Woo-Jung Park, Gayeong Kim, Seo Yeon Kim, Hyeran Won, Yun-Ho Hwang, Heeji Lim, Hyeon Guk Kim, You-Jin Kim, Dokeun Kim, Jung-Ah Lee

Journal: PLoS ONE

PubMed ID: 38060612

Doi: 10.1371/journal.pone.0295594

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, an AP2 and B3 Transcription Factor, Positively Regulates Eggplant's Response to Salt Stress

Authors: Junjie Ding, Bowen Yao, Xu Yang, Lei Shen

Journal: Plants (Basel)

PubMed ID: 38140500

Doi: 10.3390/plants12244174

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Cas9 degradation in human cells using phage anti-CRISPR proteins

Authors: Zuriah Meacham, Luisa Arake de Tacca, Joseph Bondy-Denomy, David Rabuka, Michael Schelle

Journal: PLoS Biol

PubMed ID: 38064533

Doi: 10.1371/journal.pbio.3002431

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Authors: Ewa Hordyjewska-Kowalczyk, Wim Wuyts, Nele Boeckx, An Verdonck, Gretl Hendrickx, Geert Mortier

Journal: Clin Genet

PubMed ID: 38108099

Doi: 10.1111/cge.14474

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Differential activation of mouse and human Panx1 channel variants

Authors: Antonio Cibelli, Preeti Dohare, David C Spray, Eliana Scemes

Journal: PLoS ONE

PubMed ID: 38100403

Doi: 10.1371/journal.pone.0295710

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The nuclease-associated short prokaryotic Argonaute system nonspecifically degrades DNA upon activation by target recognition

Authors: Xueling Lu, Jun Xiao, Longfei Wang, Bin Zhu, Fengtao Huang

Journal: Nucleic Acids Res

PubMed ID: 38048327

Doi: 10.1093/nar/gkad1145

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"Stronger than I thought I was": Older Adults' Coping across Two Years of the COVID-19 Pandemic

Authors: Heather R Fuller, Andrea Huseth-Zosel, Emily Kinkade, Bryce Van Vleet, Melisa Hajdar

Journal: Gerontologist

PubMed ID: 38109780

Doi: 10.1093/geront/gnad164

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Expression of the non-neuronal cholinergic system components in Malpighian tubules of Mythimna separata and evidence for non-neuronal acetylcholine synthesis

Authors: Baolei Zhan, Ting Zhou, Di Tong, Zile Xu, Xiaoyu Liang, Anqi Ma, Shumin Lü

Journal: Insect Biochem Mol Biol

PubMed ID: 38072082

Doi: 10.1016/j.ibmb.2023.104047

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The V2 domain of HIV gp120 mimics an interaction between CD4 and integrin ⍺4β7

Authors: Donald Van Ryk, Sinmanus Vimonpatranon, Joe Hiatt, Sundar Ganesan, Nathalie Chen, Jordan McMurry, Saadiq Garba, Susie Min, Livia R Goes, Alexandre Girard, Jason Yolitz, Isabella Licavoli, Danlan Wei, Dawei Huang, Marcelo A Soares, Elena Martinelli, Claudia Cicala, James Arthos

Journal: PLoS Pathog

PubMed ID: 38064524

Doi: 10.1371/journal.ppat.1011860

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Factors influencing COVID-19 mortality among cancer patients: A Brazilian multi-institutional study

Authors: Jessé Lopes da Silva, Bruno Santos Wance de Souza, Lucas Zanetti de Albuquerque, Sabina Bandeira Aleixo, Gilmara Anne da Silva Resende, Daniela Galvão Barros de Oliveira, Emerson Neves Dos Santos, Angélica Nogueira-Rodrigues, Renan Orsati Clara, Maria de Fatima Dias Gaui, Augusto Cesar de Andrade Mota, Vladmir Claudio Cordeiro de Lima, Daniela Dornelles Rosa, Rodrigo Ramella Munhoz, Igor Alexandre Protzner Morbeck, Ana Caroline Zimmer Gelatti, Clarissa Maria de Cerqueira Mathias, Andréia Cristina de Melo

Journal: PLoS ONE

PubMed ID: 38127882

Doi: 10.1371/journal.pone.0295597

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Computational design of scFv anti-receptor binding domain of SARS-CoV-2 spike protein based on antibody S230 anti-SARS-CoV-1

Authors: Ade R R Firdaus, Umi Baroroh, Taufik Ramdani Tohari, Ari Hardianto, Toto Subroto, Muhammad Yusuf

Journal: J Biomol Struct Dyn

PubMed ID: 37880854

Doi: 10.1080/07391102.2023.2265485

Products & Services: Proteins, Expression, Isolation and Analysis

Combining protein and metabolic engineering strategies for high-level production of L-theanine in Corynebacterium glutamicum

Authors: Taowei Yang, Di Zhang, Mengmeng Cai, Hengwei Zhang, Xuewei Pan, Jiajia You, Xian Zhang, Meijuan Xu, Zhiming Rao

Journal: Bioresour Technol

PubMed ID: 38103752

Doi: 10.1016/j.biortech.2023.130200

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Anxiety and dysautonomia symptoms in patients with a Na17 mutation and the potential benefits of low-dose short-acting guanfacine

Authors: Rita de Cássia Collaço, Maxime Lammens, Carley Blevins, Kristen Rodgers, Andrei Gurau, Suguru Yamauchi, Christine Kim, Jeannine Forrester, Edward Liu, Jinny Ha, Yuping Mei, Corrine Boehm, Elizabeth Wohler, Nara Sobreira, Peter C Rowe, David Valle, Malcolm V Brock, Frank Bosmans

Journal: Clin Auton Res

PubMed ID: 38064009

Doi: 10.1007/s10286-023-01004-1

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Shank3 ameliorates neuronal injury after cerebral ischemia/reperfusion via inhibiting oxidative stress and inflammation

Authors: Hongchen Zhang, Yuan Feng, Yanfang Si, Chuanhao Lu, Juan Wang, Shiquan Wang, Liang Li, Wenyu Xie, Zheming Yue, Jia Yong, Shuhui Dai, Lei Zhang, Xia Li

Journal: Redox Biol

PubMed ID: 38064762

Doi: 10.1016/j.redox.2023.102983

Products & Services: Proteins, Expression, Isolation and Analysis

Anti-inflammatory effects of neuregulin-1 in HaCaT keratinocytes and atopic dermatitis-like mice stimulated with Der p 38

Authors: Jeong Hee Yun, Yujin Hong, Min Hwa Hong, Geunyeong Kim, Ji-Sook Lee, Ran-Sook Woo, Juram Lee, Eun Ju Yang, In Sik Kim

Journal: Cytokine

PubMed ID: 38134557

Doi: 10.1016/j.cyto.2023.156439

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Development of a therapeutic monoclonal antibody against circulating adipocyte fatty acid binding protein to treat ischaemic stroke

Authors: Boya Liao, Shilun Yang, Leiluo Geng, Jiuyu Zong, Zixuan Zhang, Mengxue Jiang, Xue Jiang, Simeng Li, Aimin Xu, Junlei Chang, Ruby Lai Chong Hoo

Journal: Br J Pharmacol

PubMed ID: 37949671

Doi: 10.1111/bph.16282

Products & Services: Proteins, Expression, Isolation and Analysis

Plant-based meat analogues enhance the gastrointestinal motility function and appetite of mice by specific volatile compounds and peptides

Authors: Yunting Xie, Linlin Cai, Mengzhen Ding, Kai Shan, Di Zhao, Guanghong Zhou, Chunbao Li

Journal: Food Research International

Doi: 10.1016/j.foodres.2023.113551

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Potential of Nano-Engineered Stem Cells in the Treatment of Multiple Sclerosis: A Comprehensive Review

Authors: Sushruta Ghosh, Gurjit Kaur Bhatti, Pushpender Kumar Sharma, Ramesh Kandimalla, Sarabjit Singh Mastana, Jasvinder Singh Bhatti

Journal: Cell Mol Neurobiol

PubMed ID: 38104307

Doi: 10.1007/s10571-023-01434-5

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A semi-quantitative upconversion nanoparticle-based immunochromatographic assay for SARS-CoV-2 antigen detection

Authors: Hai Ding, Wanying Zhang, Shu-An Wang, Chuang Li, Wanting Li, Jing Liu, Fang Yu, Yanru Tao, Siyun Cheng, Hui Xie, Yuxin Chen

Journal: Front Microbiol

PubMed ID: 38149276

Doi: 10.3389/fmicb.2023.1289682

Products & Services: Proteins, Expression, Isolation and Analysis

DNA methylation editing in zebrafish

Authors: Fang Liang, Zijiong Dong, Jianmin Ye, Wei Hu, Ramji Kumar Bhandari, Kangsen Mai, Xuegeng Wang

Journal: Epigenetics

PubMed ID: 36945831

Doi: 10.1080/15592294.2023.2192326

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Antibody Response to SARS-CoV-2 Vaccination in Patients with End-Stage Kidney Disease on Hemodialysis

Authors: Rizky Andhika, Muhammad Iqbal Anand, Marita Restie Tiara, Josephine Debora, Hofiya Djauhari, Evan Susandi, Adnes Mareta, Asep Riswoko, Nopi Susilawati, Agnes Rengga Indrati, Bachti Alisjahbana, Rudi Supriyadi

Journal: Vaccines (Basel)

PubMed ID: 38140206

Doi: 10.3390/vaccines11121802

Products & Services: Plasmids for SARS-CoV-2 Detection and Research

Dissecting components of the gene cluster under iron limitation

Authors: Tomas Richardson-Sanchez, Anson C K Chan, Brendil Sabatino, Helen Lin, Erin C Gaynor, Michael E P Murphy

Journal: Microbiol Spectr

PubMed ID: 38096459

Doi: 10.1128/spectrum.03148-23

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High-resolution HLA genotyping in inclusion body myositis refines 81 ancestral haplotype association to DRB1*03:01:01 and highlights pathogenic role of arginine-74 of DRβ1 chain

Authors: Nataliya Slater, Anuradha Sooda, Emily McLeish, Kelly Beer, Anna Brusch, Rakesh Shakya, Christine Bundell, Ian James, Abha Chopra, Frank L Mastaglia, Merrilee Needham, Jerome D Coudert

Journal: J Autoimmun

PubMed ID: 38043487

Doi: 10.1016/j.jaut.2023.103150

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Bivalent inhibitors of the BTB E3 ligase KEAP1 enable instant NRF2 activation to suppress acute inflammatory response

Authors: Mengchen Lu, Jianai Ji, Yifei Lv, Jing Zhao, Yuting Liu, Qiong Jiao, Tian Liu, Yi Mou, Qidong You, Zhengyu Jiang

Journal: Cell Chem Biol

PubMed ID: 38157852

Doi: 10.1016/j.chembiol.2023.12.005

Products & Services: PCR Cloning and Subcloning

Generation and Characterization of an Influenza D Reporter Virus

Authors: Lukas Probst, Laura Laloli, Manon Flore Licheri, Matthias Licheri, Mitra Gultom, Melle Holwerda, Philip V'kovski, Ronald Dijkman

Journal: Viruses

PubMed ID: 38140686

Doi: 10.3390/v15122444

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Targeted HBx gene editing by CRISPR/Cas9 system effectively reduces epithelial to mesenchymal transition and HBV replication in hepatoma cells

Authors: Preety Rawal, Dinesh Mani Tripathi, Hamed Hemati, Jitendra Kumar, Purnima Tyagi, Shiv Kumar Sarin, Vikrant Nain, Savneet Kaur

Journal: Liver Int

PubMed ID: 38105495

Doi: 10.1111/liv.15805

A randomized phase II study of acyclovir for the prevention of chemotherapy-induced oral mucositis in patients undergoing autologous hematopoietic stem cell transplantation

Authors: Junshik Hong, Hee-Kyung Park, Sung-Ho Chang, Ja Min Byun, Dong-Yeop Shin, Youngil Koh, Sung-Soo Yoon, Youngnim Choi, Inho Kim

Journal: BMC Oral Health

PubMed ID: 38102638

Doi: 10.1186/s12903-023-03623-6

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Elevated BMI reduces the humoral response to SARS-CoV-2 infection

Authors: Marcus Zw Tong, Julian Dj Sng, Meagan Carney, Lucy Cooper, Samuel Brown, Katie E Lineburg, Keng Yih Chew, Neve Collins, Kirsten Ignacio, Megan Airey, Lucy Burr, Briony A Joyce, Dhilshan Jayasinghe, Christopher Ld McMillan, David A Muller, Anurag Adhikari, Linda A Gallo, Emily S Dorey, Helen L Barrett, Stephanie Gras, Corey Smith, Kim Good-Jacobson, Kirsty R Short

Journal: Clin Transl Immunology

PubMed ID: 38050635

Doi: 10.1002/cti2.1476

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CD1d facilitates African swine fever virus entry into the host cells via clathrin-mediated endocytosis

Authors: Xin Chen, Jun Zheng, Chuanxia Liu, Tingting Li, Xiao Wang, Xuewen Li, Miaofei Bao, Jiangnan Li, Li Huang, Zhaoxia Zhang, Zhigao Bu, Changjiang Weng

Journal: Emerg Microbes Infect

PubMed ID: 37254454

Doi: 10.1080/22221751.2023.2220575

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Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding

Authors: Fanchong Jian, Leilei Feng, Sijie Yang, Yuanling Yu, Lei Wang, Weiliang Song, Ayijiang Yisimayi, Xiaosu Chen, Yanli Xu, Peng Wang, Lingling Yu, Jing Wang, Lu Liu, Xiao Niu, Jing Wang, Tianhe Xiao, Ran An, Yao Wang, Qingqing Gu, Fei Shao, Ronghua Jin, Zhongyang Shen, Youchun Wang, Xiangxi Wang, Yunlong Cao

Journal: PLoS Pathog

PubMed ID: 38117863

Doi: 10.1371/journal.ppat.1011868

Products & Services: Proteins, Expression, Isolation and Analysis

Enhancement of SARS-CoV-2 Infection via Crosslinking of Adjacent Spike Proteins by N-Terminal Domain-Targeting Antibodies

Authors: Tina Lusiany, Tohru Terada, Jun-Ichi Kishikawa, Mika Hirose, David Virya Chen, Fuminori Sugihara, Hendra Saputra Ismanto, Floris J van Eerden, Songling Li, Takayuki Kato, Hisashi Arase, Matsuura Yoshiharu, Masato Okada, Daron M Standley

Journal: Viruses

PubMed ID: 38140662

Doi: 10.3390/v15122421

Products & Services: Peptide Synthesis

A lipid membrane-centric role of the SQSTM1/p62 body during autophagosome formation

Authors: Jinpei Zhang, Xintong He, Na Mi

Journal: Autophagy

PubMed ID: 38115546

Doi: 10.1080/15548627.2023.2297622

Products & Services: Plasmid DNA Preparation

Screening of novel DPP-IV inhibitory peptides derived from bovine milk proteins using a peptide array platform

Authors: Sayuri Arai, Masaki Kurimoto, Hajime Nakada, Masayoshi Tanaka, Hiroshi Ochi, Miyuki Tanaka, Mina Okochi

Journal: J Biosci Bioeng

PubMed ID: 38092600

Doi: 10.1016/j.jbiosc.2023.11.007

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Template and target-site recognition by human LINE-1 in retrotransposition

Authors: Akanksha Thawani, Alfredo Jose Florez Ariza, Eva Nogales, Kathleen Collins

Journal: Nature

PubMed ID: 38096901

Doi: 10.1038/s41586-023-06933-5

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Overlapping characteristics of weak interactions of two transcriptional regulators with WDR5

Authors: Mohammad Ahmad, Ali Imran, Liviu Movileanu

Journal: Int J Biol Macromol

PubMed ID: 38158065

Doi: 10.1016/j.ijbiomac.2023.128969

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a fluorescent multiplexed lateral flow immunoassay for the simultaneous detection of crustacean allergen tropomyosin, sarcoplasmic calcium binding protein and egg allergen ovalbumin in different matrices and commercial foods

Authors: Yuhao Huang, Ranran Li, Wenye Zhu, Jinlong Zhao, Hao Wang, Ziye Zhang, Hong Lin, Wenjie Li, Zhenxing Li

Journal: Food Chem

PubMed ID: 38150909

Doi: 10.1016/j.foodchem.2023.138275

Products & Services: Proteins, Expression, Isolation and Analysis

Copper assisted sequence-specificchemical protein conjugation at a single backbone amide

Authors: Mengzhun Guo , Kai Zhao , Liang Guo , Rui Zhou , Qiuju He , Kuan Lu , Tian Li, Dandan Liu , Jinfeng Chen , Jing Tang , Xin Fu , Jinyun Zhou , Bei Zheng , Samuel I Mann , Yongdeng Zhang , Jing Huang , Bing Yang , Ting Zhou , Yingjie Lei , Bobo Dang

Journal: Nat Commun

PubMed ID: 38052794

Doi: 10.1038/s41467-023-43753-7

Products & Services: Proteins, Expression, Isolation and Analysis

Rational design of an influenza-COVID-19 chimeric protective vaccine with HA-stalk and S-RBD

Authors: Yulei Li, Peipei Liu, Tianjiao Hao, Sheng Liu, Xi Wang, Yufeng Xie, Ke Xu, Wenwen Lei, Cheng Zhang, Pu Han, Ying Li, Xiyue Jin, Yu Huan, Yafei Lu, Rong Zhang, Xiaoyan Li, Xin Zhao, Kun Xu, Pu Liao, Xuancheng Lu, Yuhai Bi, Hao Song, Guizhen Wu, Baoli Zhu, George F Gao

Journal: Emerg Microbes Infect

PubMed ID: 37394992

Doi: 10.1080/22221751.2023.2231573

Products & Services: Gene Synthesis

Revitalizing Skin Repair: Unveiling the Healing Power of Livisin, a Natural Peptide Calcium Mimetic

Authors: Xuehui Zhan, Danni Wang, Hanfei Wang, Hui Chen, Xinyi Wu, Tao Li, Junmei Qi, Tianbao Chen, Di Wu, Yitian Gao

Journal: Toxins

PubMed ID: 38251238

Doi: 10.3390/toxins16010021

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Anti-virulence and bactericidal activities of Stattic against Shigella sonnei

Authors: Mingfang Wang, Jia Zeng, Huihui Tan, Quan Guo, Xia Li, Xiwen Ling, Jinyue Zhang, Shihao Song, Yinyue Deng

Journal: Appl Environ Microbiol .

PubMed ID: 38032177

Doi: 10.1128/aem.01074-23

Products & Services: Proteins, Expression, Isolation and Analysis

α-Synuclein emulsifies TDP-43 prion-like domain-RNA liquid droplets to promote heterotypic amyloid fibrils

Authors: Shailendra Dhakal, Malay Mondal, Azin Mirzazadeh, Siddhartha Banerjee, Ayanjeet Ghosh, Vijayaraghavan Rangachari

Journal: Commun Biol

PubMed ID: 38052886

Doi: 10.1038/s42003-023-05608-1

Products & Services: Proteins, Expression, Isolation and Analysis

Redeveloping antigen detection kits for the diagnosis of rat hepatitis E virus

Authors: Zihao Chen, Guanghui Li, Jianwen Situ, Zhiyong Li, Shaoqi Guo, Yang Huang, Shusheng Wu, Zimin Tang, Guiping Wen, Siling Wang, Mujin Fang, Yingbin Wang, Hai Yu, Siddharth Sridhar, Zizheng Zheng, Ningshao Xia

Journal: J Clin Microbiol

PubMed ID: 38038482

Doi: 10.1128/jcm.00710-23

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Protocol for precision editing of endogenous Chlamydomonas reinhardtii genes with CRISPR-Cas

Authors: Adrian Pascal Nievergelt, Dennis Ray Diener, Aliona Bogdanova, Thomas Brown, Gaia Pigino

Journal: STAR Protoc

PubMed ID: 38096061

Doi: 10.1016/j.xpro.2023.102774

Products & Services: CRISPR Plasmids

Base editing of the HBG promoter induces potent fetal hemoglobin expression with no detectable off-target mutations in human HSCs

Authors: Wenyan Han, Hou-Yuan Qiu, Shangwu Sun, Zhi-Can Fu, Guo-Quan Wang, Xiaowen Qian, Lijie Wang, Xiaowen Zhai, Jia Wei, Yichuan Wang, Yi-Lin Guo, Guo-Hua Cao, Rui-Jin Ji, Yi-Zhou Zhang, Hongxia Ma, Hongsheng Wang, Mingli Zhao

Journal: Cell Stem Cell

PubMed ID: 37989316

Doi: 10.1016/j.stem.2023.10.007

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A plasmid containing the human metallothionein-II gene selectively distinguishes trivalent lanthanum from several divalent heavy metal cations during monoclonal antibody-assisted agarose gel electrophoresis

Authors:

Journal: Toxicol Ind Health

PubMed ID: 38095284

Doi: 10.1177/07482337231222354

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Activation and characterization of G protein-coupled receptors for CHHs in the mud crab, Scylla paramamosain

Authors: Nan Mo, Shucheng Shao, Yan Zhuang, Yanan Yang, Zhaoxia Cui, Chenchang Bao

Journal: Comp Biochem Physiol A Mol Integr Physiol

PubMed ID: 38122925

Doi: 10.1016/j.cbpa.2023.111563

Products & Services: Proteins, Expression, Isolation and Analysis

Resveratrol-derived inhibitors of the E3 ubiquitin ligase PELI1 inhibit the metastasis of triple-negative breast cancer

Authors: Guangsen Xu, Qian Zhou, Jie Qi, Zhongyue Li, Lijun Yin, Zhuoran Li, Chunhua Lu, Baobing Zhao, Yuemao Shen

Journal: Eur J Med Chem

PubMed ID: 38150964

Doi: 10.1016/j.ejmech.2023.116060

Products & Services: PCR Cloning and Subcloning

Akt may associate with insulin-responsive vesicles via interaction with sortilin

Authors: Nava Zaarur, Anatoli B Meriin, Maneet Singh, Raghuveera K Goel, Joseph Zaia, Konstantin V Kandror

Journal: FEBS Lett

PubMed ID: 38105115

Doi: 10.1002/1873-3468.14790

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Worsening of imiquimod-induced psoriasiform inflammation in mice by environmental pollutant, di-(2-ethylhexyl) phthalate through dysregulation in IL-17A and Nrf2/iNOS signaling in peripheral myeloid and CD4 + T cells

Authors: Ali S Alfardan, Ahmed Nadeem, Sheikh F Ahmad, Naif O Al-Harbi, Mohammed Alqinyah, Sabry M Attia, Wedad Sarawi, Ahmed Z Alanazi, Khalid Alhazzani, Khalid E Ibrahim

Journal: Int Immunopharmacol

PubMed ID: 38056199

Doi: 10.1016/j.intimp.2023.111293

Products & Services: PCR Cloning and Subcloning

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