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The lncRNA HCG4 regulates the RIG-I-mediated IFN production to suppress H1N1 swine influenza virus replication

Authors: Jinghua Cheng, Jie Tao, Benqiang Li, Ying Shi, Huili Liu

Journal: Front Microbiol

PubMed ID: 38274760

Doi: 10.3389/fmicb.2023.1324218

Products & Services: Proteins, Expression, Isolation and Analysis

Predicting multiple conformations via sequence clustering and AlphaFold2

Authors: Hannah K Wayment-Steele, Adedolapo Ojoawo, Renee Otten, Julia M Apitz, Warintra Pitsawong, Marc Hömberger, Sergey Ovchinnikov, Lucy Colwell, Dorothee Kern

Journal: Nature

PubMed ID: 37956700

Doi: 10.1038/s41586-023-06832-9

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N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting

Authors: Thomas E Mulroney, Tuija Pöyry, Juan Carlos Yam-Puc, Maria Rust, Robert F Harvey, Lajos Kalmar, Emily Horner, Lucy Booth, Alexander P Ferreira, Mark Stoneley, Ritwick Sawarkar, Alexander J Mentzer, Kathryn S Lilley, C Mark Smales, Tobias von der Haar, Lance Turtle, Susanna Dunachie, Paul Klenerman, James E D Thaventhiran, Anne E Willis

Journal: Nature

PubMed ID: 38057663

Doi: 10.1038/s41586-023-06800-3

Products & Services: PCR Cloning and Subcloning

Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques

Authors: Rajeshwer S Sankhala , Kerri G Lal , Jaime L Jensen , Vincent Dussupt , Letzibeth Mendez-Rivera , Hongjun Bai , Lindsay Wieczorek , Sandra V Mayer , Michelle Zemil , Danielle A Wagner , Samantha M Townsley , Agnes Hajduczki , William C Chang , Wei-Hung Chen , Gina C Donofrio , Ningbo Jian , Hannah A D King , Cynthia G Lorang , Elizabeth J Martinez , Phyllis A Rees , Caroline E Peterson , Fabian Schmidt , Tricia J Hart , Debra K Duso , Lawrence W Kummer , Sean P Casey , Jazmean K Williams , Shruthi Kannan , Bonnie M Slike , Lauren Smith , Isabella Swafford , Paul V Thomas , Ursula Tran , Jeffrey R Currier , Diane L Bolton , Edgar Davidson , Benjamin J Doranz , Theodora Hatziioannou , Paul D Bieniasz , Dominic Paquin-Proulx , William W Reiley , Morgane Rolland , Nancy J Sullivan , Sandhya Vasan , Natalie D Collins , Kayvon Modjarrad , Gregory D Gromowski , Victoria R Polonis , Nelson L Michael , Shelly J Krebs , M Gordon Joyce

Journal: Nat Commun

PubMed ID: 38172512

Doi: 10.1038/s41467-023-44265-0.

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Therapeutic vaccination with lentiviral vector in HBV-persistent mice and two inactive HBsAg carriers

Authors: Yumeng Zhang, Maryline Bourgine , Yanmin Wan, Jieyu Song, Zongying Li, Yiqi Yu, Wangfang Jiang, Mingzhe Zhou, Cuiyuan Guo, Didier Santucci, Xiao Liang, Christian Brechot, Wenhong Zhang, Pierre Charneau, Hong Wu, Chao Qiu

Journal: Hepatology

PubMed ID: 37827470

Doi: 10.1016/j.jhep.2023.09.019

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A new antibiotic traps lipopolysaccharide in its intermembrane transporter

Authors: Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth Bradley, Andrew C Kruse 4, Daniel Kahne 5

Journal: Nature

PubMed ID: 38172635

Doi: 10.1038/s41586-023-06799-7

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Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution

Authors: Jason Z. Zhang, William H. Nguyen, Nathan Greenwood, John C. Rose, Shao-En Ong, Dustin J. Maly & David Baker

Journal: Nature Biotechnol

PubMed ID: 38228150

Doi: 10.1038/s41587-023-02107-w

Products & Services: Plasmid DNA Preparation

Structure-guided discovery of anti-CRISPR and anti-phage defense proteins

Authors: Ning Duan , Emily Hand , Mannuku Pheko , Shikha Sharma , Akintunde Emiola

Journal: Nat Commun

PubMed ID: 38245560

Doi: 10.1038/s41467-024-45068-7

Products & Services: Codon Optimization

Stabilization of the Metastable Pre-Fusion Conformation of the SARS-CoV-2 Spike Glycoprotein through N-Linked Glycosylation of the S2 Subunit

Authors: Fuwen Zan, Yao Zhou, Ting Chen , Yahan Chen, Zhixia Mu, Zhaohui Qian , Xiuyuan Ou

Journal: Viruses.

PubMed ID: 38399999

Doi: 10.3390/v16020223

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Modulations in the host cell proteome by the hantavirus nucleocapsid protein

Authors: Austin Royster, Songyang Ren, Saima Ali, Sheema Mir, Mohammad Mir

Journal: PLoS Pathog

PubMed ID: 38190410

Doi: 10.1371/journal.ppat.1011925

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A label-free high-throughput protein solubility assay and its application to Aβ40

Authors: Max Lindberg, Emil Axell, Emma Sparr, Sara Linse

Journal: Biophys Chem

PubMed ID: 38309218

Doi: 10.1016/j.bpc.2023.107165

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Identification of a novel B-cell epitope of the African swine fever virus p34 protein and development of an indirect ELISA for the detection of serum antibodies

Authors: Yuanyuan Tian, Chao Liang, Jingming Zhou, Fanglin Sun, Yankai Liu, Yumei Chen, Xifang Zhu, Hongliang Liu, Peiyang Ding, Enping Liu, Ying Zhang, Sixuan Wu, Aiping Wang

Journal: Front Microbiol

PubMed ID: 38282734

Doi: 10.3389/fmicb.2023.1308753

Variation of C-terminal domain governs RNA polymerase II genomic locations and alternative splicing in eukaryotic transcription

Authors: Qian Zhang, Wantae Kim, Svetlana Panina, Joshua E Mayfield, Bede Portz, Y Jessie Zhang

Journal: biorxiv

PubMed ID: 38260389

Doi: 10.1101/2024.01.01.573828

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Role of PLK1/NUMB/NOTCH in epithelial-mesenchymal transition in human melanoma

Authors: Gagan Chhabra, Chandra K Singh, Mary A Ndiaye, Shengqin Su, Carl A Shirley, Nihal Ahmad

Journal: NPJ Precis Oncol

PubMed ID: 38184733

Doi: 10.1038/s41698-023-00493-7

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Mining and rational design of psychrophilic catalases using metagenomics and deep learning models

Authors: Shuning Wu, Guoshun Xu, Yongping Su, Huoqing Huang, Xinxin Xu, Yuhong Zhang, Jian Tian, Wei Zhang, Zhiwei Zhang, Bo Liu

Journal: Appl Microbiol Biotechnol

PubMed ID: 38175233

Doi: 10.1007/s00253-023-12926-1

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S100A12 protein as a porcine health status biomarker when quantified in saliva samples

Authors: A M Gutiérrez, M Matas-Quintanilla, M Piñeiro, J Sánchez, P Fuentes, F J Ibáñez-López

Journal: Vet J

PubMed ID: 38215874

Doi: 10.1016/j.tvjl.2024.106062

Products & Services: Proteins, Expression, Isolation and Analysis

A high catalytic efficiency and chemotolerant formate dehydrogenase from Bacillus simplex

Authors: Rattima Boonkumkrong, Paweenapon Chunthaboon, Pobthum Munkajohnpong, Pratchaya Watthaisong, Panu Pimviriyakul, Somchart Maenpuen, Pimchai Chaiyen, Ruchanok Tinikul

Journal: Biotechnol J

PubMed ID: 38180313

Doi: 10.1002/biot.202300330

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Sast1-mediated manifold effects inhibit Plutella xylostella fertility

Authors: Min-Hui Cao, Ming-Min Zou, Li-Li Liu, Shi-Jie Dong, Meng-Qi Huang, Jun-Hao Zheng, Ruo-Nan Li, Jin-Dong Cui, Lu Peng

Journal: Pest Manag Sci

PubMed ID: 38252701

Doi: 10.1002/ps.7966

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Self-cascade deoxynivalenol detoxification by an artificial enzyme with bifunctions of dehydrogenase and aldo/keto reductase from genome mining

Authors: Jiafeng Niu, Ruxue Yan, Huimin Zhou, Bin Ma, Zhaoxin Lu, Fanqiang Meng, Fengxia Lu, Ping Zhu

Journal: Int J Biol Macromol

PubMed ID: 38246466

Doi: 10.1016/j.ijbiomac.2024.129512

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VEGF-delivering PEG hydrogels promote vascularization in the porcine subcutaneous space

Authors: Michelle J Quizon, Juline N Deppen, Graham F Barber, Pranav P Kalelkar, María M Coronel, Rebecca D Levit, Andres J Garcia

Journal: J Biomed Mater Res A

PubMed ID: 38189109

Doi: 10.1002/jbm.a.37666

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Nitrated T cell epitope linked vaccine targeting CD47 elicits antitumor immune responses and acts synergistically with vaccine targeting PDL1

Authors: Danni Deng, Guozhi Li, Xuefei Xia, Shuyang Xu, Le Gao, Li Zhang, Wenbing Yao, Hong Tian, Xiangdong Gao

Journal: Int Immunopharmacol

PubMed ID: 38181672

Doi: 10.1016/j.intimp.2023.111374

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FS145, the first flea-derived disintegrin, inhibits angiogenesis through specifically binding integrin αβ

Authors: Wancheng Lu, Zhijian Xiao, Hang Liao, Jianpeng Xie, Yihan Gao, Weichen Xiong, Qingye Zeng, Zhenhui Deng, Jiena Wu, Jinwei Chai, Xin Chen, Xueqing Xu

Journal: Int J Biol Macromol

PubMed ID: 38211910

Doi: 10.1016/j.ijbiomac.2024.129289

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Development of nanobodies specific to clumping factors A of Staphylococcus aureus by yeast surface display

Authors: Meng Mei, Mengqing Lu, Shiqi Li, Xinyi Ren, Banbin Xing, Yang Hu, Yuqi Wu, Huan Chen, Longhao Wang, Li Yi, Ke Ming, Zigong Wei

Journal: Int J Biol Macromol

PubMed ID: 38185298

Doi: 10.1016/j.ijbiomac.2024.129208

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Immunogenicity studies of recombinant RBD SARS-CoV-2 as a COVID-19 vaccine candidate produced in

Authors: Intan Aghniya Safitri, Yovin Sugijo, Fernita Puspasari, Fifi Fitriyah Masduki, Ernawati Arifin Giri-Rachman, Aluicia Anita Artarini, Marselina Irasonia Tan, Dessy Natalia

Journal: Vaccine X

PubMed ID: 38304876

Doi: 10.1016/j.jvacx.2024.100443

Products & Services: Molecular Biology Reagents

Genetic engineering employing MPB70 and its promoter enables efficient secretion and expression of foreign antigen in bacillus Calmette Guérin (BCG) Tokyo

Authors: Atsuki Takeishi, Amina K Shaban, Taichi Kakihana, Hayato Takihara, Shujiro Okuda, Hidekazu Osada, Desak Nyoman Surya Suameitria Dewi, Yuriko Ozeki, Yutaka Yoshida, Akihito Nishiyama, Yoshitaka Tateishi, Yuki Aizu, Yasushi Chuma, Kazuyo Onishi, Daisuke Hayashi, Saburo Yamamoto, Tetsu Mukai, Manabu Ato, Duong Huu Thai, Huynh Thi Thao Nhi, Tsuyoshi Shirai, Satoshi Shibata, Fumiko Obata, Jun Fujii, Seiya Yamayoshi, Maki Kiso, Sohkichi Matsumoto

Journal: Microbiol Immunol

PubMed ID: 38294180

Doi: 10.1111/1348-0421.13116

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Studying the topology of peroxisomal acyl-CoA synthetases using self-assembling split sfGFP

Authors: Serhii Chornyi, Janet Koster, Lodewijk IJlst, Hans R Waterham

Journal: Histochem Cell Biol

PubMed ID: 38243092

Doi: 10.1007/s00418-023-02257-7

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Performance Analysis of Serodiagnostic Tests to Characterize the Incline and Decline of the Individual Humoral Immune Response in COVID-19 Patients: Impact on Diagnostic Management

Authors: Ronald von Possel, Babett Menge, Christina Deschermeier, Carlos Fritzsche, Christoph Hemmer, Hilte Geerdes-Fenge, Micha Loebermann, Anette Schulz, Erik Lattwein, Katja Steinhagen, Ralf Tönnies, Reiner Ahrendt, Petra Emmerich

Journal: Viruses

PubMed ID: 38257792

Doi: 10.3390/v16010091

Products & Services: Proteins, Expression, Isolation and Analysis

Generation and Application of Monoclonal Antibodies against Porcine S100A8, S100A9, and S100A12 Proteins Using Hybridoma Technology

Authors: Pengpeng Xia, Xin Ma, Li Yan, Siqi Lian, Xiangyu Li, Yi Luo, Ziyue Chen, Xingduo Ji

Journal: Int J Mol Sci

PubMed ID: 38256103

Doi: 10.3390/ijms25021029

Products & Services: Proteins, Expression, Isolation and Analysis

A Non-Functional Carbon Dioxide-Mediated Post-Translational Modification on Nucleoside Diphosphate Kinase of

Authors: Harry G Gannon, Amber Riaz-Bradley, Martin J Cann

Journal: Int J Mol Sci

PubMed ID: 38255974

Doi: 10.3390/ijms25020898

Products & Services: Proteins, Expression, Isolation and Analysis

Role of Histiocyte-Derived frHMGB1 as a Facilitator in Non-Canonical Pyroptosis of Monocytes/Macrophages in Lethal Sepsis

Authors: Yu Tian, Yuwen Cao, Fang Liu, Lin Xia, Chao Wang, Zhaoliang Su

Journal: J Infect Dis

PubMed ID: 38243905

Doi: 10.1093/infdis/jiae020

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Chimeric proteins of Mycoplasma hyopneumoniae as vaccine and preclinical model for immunological evaluation

Authors: Marcus Rebouças Santos, Leonardo Teófilo Toledo, Ênio José Bassi, Wagnner José Nascimento Porto, Gustavo Costa Bressan, Maria Aparecida S Moreira, Yung-Fu Chang, Abelardo Silva-Júnior

Journal: Braz J Microbiol

PubMed ID: 38217795

Doi: 10.1007/s42770-023-01240-7

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Electrically silent KvS subunits associate with native Kv2 channels in brain and impact diverse properties of channel function

Authors: Michael Ferns, Deborah van der List, Nicholas C Vierra, Taylor Lacey, Karl Murray, Michael Kirmiz, Robert G Stewart, Jon T Sack, James S Trimmer

Journal: biorxiv

PubMed ID: 38328147

Doi: 10.1101/2024.01.25.577135

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Recombinant T7 RNA polymerase production using ClearColi BL21(DE3) and animal-free media for in vitro transcription

Authors: Qianying Liang, Bowen Tu, Lun Cui

Journal: Appl Microbiol Biotechnol

PubMed ID: 38180552

Doi: 10.1007/s00253-023-12939-w

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Astragaloside IV regulates circ_0001615 and miR-873-5p/LASP1 axis to suppress colorectal cancer cell progression

Authors: Pengfei Kong, Xuemei Tang, Fang Liu, Xuegui Tang

Journal: Chem Biol Drug Des

PubMed ID: 38230773

Doi: 10.1111/cbdd.14423

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Prevalence of IgG antibodies against Malawi polyomavirus in patients with autoimmune diseases and lymphoproliferative disorders subjected to bone marrow transplantation

Authors: Jérôme T J Nicol, Elisa Mazzoni, Maria Rosa Iaquinta, Raffaella De Pace, Pauline Gaboriaud, Natalia Maximova, Carolina Cason, Eleonora De Martino, Chiara Mazziotta, Pierre Coursaget, Antoine Touzé, Valentina Boz, Manola Comar, Mauro Tognon, Fernanda Martini

Journal: Front Immunol

PubMed ID: 38299147

Doi: 10.3389/fimmu.2023.1293313

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Evolutionary preservation of CpG dinucleotides in RAG1 may elucidate the relatively high rate of methylation-mediated mutagenesis of RAG1 transposase

Authors: Mariam M Fawzy, Maiiada H Nazmy, Azza A K El-Sheikh, Moustafa Fathy

Journal: Immunol Res

PubMed ID: 38240953

Doi: 10.1007/s12026-023-09451-8

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Enhanced immunogenicity and protective efficacy in mice following a Zika DNA vaccine designed by modulation of membrane-anchoring regions and its association to adjuvants

Authors: Franciane Mouradian Emidio Teixeira, Luana de Mendonça Oliveira, Anna Cláudia Calvielli Castelo Branco, Ricardo Wesley Alberca, Emanuella Sarmento Alho de Sousa, Bruno Henrique de Sousa Leite, Wenny Camilla Dos Santos Adan, Alberto José da Silva Duarte, Roberto Dias Lins, Maria Notomi Sato, Isabelle Freire Tabosa Viana

Journal: Front Immunol

PubMed ID: 38361945

Doi: 10.3389/fimmu.2024.1307546

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A novel starch-active lytic polysaccharide monooxygenase discovered with bioinformatics screening and its application in textile desizing

Authors: Meijuan Zhang, Xiaoping Fu, Rongrong Gu, Bohua Zhao, Xingya Zhao, Hui Song, Hongchen Zheng, Jianyong Xu, Wenqin Bai

Journal: BMC Biotechnol

PubMed ID: 38200466

Doi: 10.1186/s12896-023-00826-1

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Inter-alpha-trypsin inhibitor (IαI) and hyaluronan modifications enhance the innate immune response to influenza virus in the lung

Authors: Fengying Tang, Stephen R Reeves, Jourdan E Brune, Mary Y Chang, Christina K Chan, Peter Waldron, Sheona P Drummond, Caroline M Milner, Kimberly M Alonge, Stavros Garantziotis, Anthony J Day, William A Altemeier, Charles W Frevert

Journal: Matrix Biol

PubMed ID: 38232913

Doi: 10.1016/j.matbio.2024.01.004

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Comparative immunogenicity and neutralizing antibody responses post heterologous vaccination with CoronaVac (Sinovac) and Vaxzevria (AstraZeneca) in HIV-infected patients with varying CD4+ T lymphocyte counts

Authors: Sorawit Chittrakarn, Pisud Siripaitoon, Sarunyou Chusri, Siripen Kanchanasuwan, Boonsri Charoenmak, Thanaporn Hortiwakul, Phaiwon Kantikit, Narongdet Kositpantawong

Journal: Hum Vaccin Immunother

PubMed ID: 38297904

Doi: 10.1080/21645515.2024.2309734

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Glycosylase-based base editors for efficient T-to-G and C-to-G editing in mammalian cells

Authors: Lijun Ye , Dongdong Zhao , Ju Li , Yiran Wang , Bo Li , Yuanzhao Yang , Xueting Hou , Huibin Wang , Zhandong Wei , Xiaoqi Liu , Yaqiu Li, Siwei Li , Yajing Liu , Xueli Zhang , Changhao Bi

Journal: Nat Biotechnol .

PubMed ID: 38168994

Doi: 10.1038/s41587-023-02050-w

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Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia

Authors: Wenhua Jiang, Qiangqiang Hou, Hongrui Xu, Kexin Yang, Xiaohui Wang, Kuojun Zhang, Yi Zeng, Wenqiang Li, Bingrui Wang, Guangmei Luo, Xiaofan Zhao, Hui Shen, Yong Xu, Xiaoxing Wu

Journal: J Med Chem

PubMed ID: 38175809

Doi: 10.1021/acs.jmedchem.3c02104

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Local Multiple-site Injections of a Plasmid Encoding Human Mitigate Radiation-induced Skin Injury by Inhibiting Ferroptosis

Authors: Xiaoying Wang, Yuxin Lu, Xiaochen Cheng, Xuefeng Zhu, Dujuan Li, Haiying Duan, Shenhui Hu, Fengjun Xiao, Li Du, Qinglin Zhang

Journal: Curr Drug Deliv

PubMed ID: 37157191

Doi: 10.2174/1567201820666230508120720

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Bioactive Polyurethane-Poly(ethylene Glycol) Diacrylate Hydrogels for Applications in Tissue Engineering

Authors: Yixuan Yuan, Caleb Tyson, Annika Szyniec, Samuel Agro, Tara N Tavakol, Alexander Harmon, DessaRae Lampkins, Lauran Pearson, Jerald E Dumas, Lakeshia J Taite

Journal: Gels

PubMed ID: 38391438

Doi: 10.3390/gels10020108

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Functionally coherent transcriptional responses of Jatropha curcas and Pseudomonas fragi for rhizosphere mediated degradation of pyrene

Authors: L Paikhomba Singha, K Malabika Singha, Piyush Pandey

Journal: Sci Rep

PubMed ID: 38200308

Doi: 10.1038/s41598-024-51581-y

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A Mixture of T-Cell Epitope Peptides Derived from Human Respiratory Syncytial Virus F Protein Conferred Protection in DR1-TCR Tg Mice

Authors: Hong Guo, Yang Song, Hai Li, Hongqiao Hu, Yuqing Shi, Jie Jiang, Jinyuan Guo, Lei Cao, Naiying Mao, Yan Zhang

Journal: Vaccines (Basel)

PubMed ID: 38250890

Doi: 10.3390/vaccines12010077

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In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy

Authors: Brandon Lam, Yu Jui Kung, John Lin, Ssu-Hsueh Tseng, Hsin-Fang Tu, Claire Huang, Brandon Lee, Esteban Velarde, Ya Chea Tsai, Rafael Villasmil, Sung Taek Park, Deyin Xing, Chien-Fu Hung, T-C Wu

Journal: J Clin Invest

PubMed ID: 37917174

Doi: 10.1172/JCI171621

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The naringenin-dependent regulator FdeR can be applied as a NIMPLY gate controlled by naringenin and arabinose

Authors: Fernanda Miyuki Kashiwagi, Brenno Wendler Miranda, Emanuel Maltempi de Souza, Marcelo Müller-Santos

Journal: Synth Biol (Oxf)

PubMed ID: 38249314

Doi: 10.1093/synbio/ysae001

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HCMV IE1/IE1mut Therapeutic Vaccine Induces Tumor Regression via Intratumoral Tertiary Lymphoid Structure Formation and Peripheral Immunity Activation in Glioblastoma Multiforme

Authors: Xiaoli Yang, Shasha Jiang, Fengjun Liu, Zonghui Li, Wenxuan Liu, Xianjuan Zhang, Fulong Nan, Jun Li, Meng Yu, Yunyang Wang, Bin Wang

Journal: Mol Neurobiol

PubMed ID: 38261253

Doi: 10.1007/s12035-024-03937-8

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A Novel Role for the Adenovirus L4 Region 22K and 33K Proteins in Adeno-Associated Virus Production

Authors: Angela Adsero, Brendan Chestnut, Sara Shahnejat-Bushehri, Lalita Sasnoor, Travis McMurphy, Mike Swenor, Ryan Pasquino, Arun Pradhan, Victor Hernandez, Linas Padegimas, David Dismuke

Journal: Hum Gene Ther

PubMed ID: 38062776

Doi: 10.1089/hum.2023.146

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Cascaded amplifying circuit enables sensitive detection of fungal pathogens

Authors: Cong Fan, Nike He, Jifeng Yuan

Journal: Biosens Bioelectron

PubMed ID: 38281368

Doi: 10.1016/j.bios.2024.116058

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An inducible CRISPRi circuit for tunable dynamic regulation of gene expression in Saccharopolyspora erythraea

Authors: Xing Jiang, Xiang Ke, Xiwei Tian, Ju Chu

Journal: Biotechnol Lett

PubMed ID: 38279045

Doi: 10.1007/s10529-023-03462-z

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Capsid protein mediated evasion of IRAK1-dependent signalling is essential to Sindbis virus neuroinvasion and virulence in mice

Authors: V Douglas Landers, Milton Thomas, Cierra M Isom, Deepa Karki, Kevin J Sokoloski

Journal: Emerg Microbes Infect

PubMed ID: 38164715

Doi: 10.1080/22221751.2023.2300452

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Estimation of the Parasitic Burden of Soil-Transmitted Helminths Among Pregnant Women in the Maharashtra State of India Using qPCR: A Community-Based Study

Authors: Shilpa Gaidhane, Abhay Gaidhane, Mahalaqua Nazli Khatib, Shital Telrandhe, Manoj Patil, Deepak Saxena, Pankaj Bhardwaj, Sonali Choudhari, Quazi S Zahiruddin

Journal: Indian J Community Med

PubMed ID: 38425985

Doi: 10.4103/ijcm.ijcm_249_23

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Mitochondrial Homeostasis Regulating Mitochondrial Number and Morphology Is a Distinguishing Feature of Skeletal Muscle Fiber Types in Marine Teleosts

Authors: Busu Li, Huan Wang, Xianghui Zeng, Shufang Liu, Zhimeng Zhuang

Journal: Int J Mol Sci

PubMed ID: 38338790

Doi: 10.3390/ijms25031512

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Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from

Authors: Fredrik Leo, Rolf Lood, Kristina A Thomsson, Jonas Nilsson, Gunnel Svensäter, Claes Wickström

Journal: Front Microbiol

PubMed ID: 38304711

Doi: 10.3389/fmicb.2024.1340109

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KDM6A Demethylase Regulates Renal Sodium Excretion and Blood Pressure

Authors: Xiaobin Han, Leah Akinseye, Zhongjie Sun

Journal: Hypertension

PubMed ID: 38164755

Doi: 10.1161/HYPERTENSIONAHA.123.22026

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Cyclic di-GMP inhibits nitrate assimilation by impairing the antitermination function of NasT in Pseudomonas putida

Authors: Liang Nie, Yujie Xiao, Tiantian Zhou, Haoqi Feng, Meina He, Qingyuan Liang, Kexin Mu, Hailing Nie, Qiaoyun Huang, Wenli Chen

Journal: Nucleic Acids Res

PubMed ID: 38000372

Doi: 10.1093/nar/gkad1117

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CGI1746 targets σ1R to modulate ferroptosis through mitochondria-associated membranes

Authors: Zili Zhang, Hong Zhou, Wenjia Gu, Yuehan Wei, Shan Mou, Youjun Wang, Jing Zhang & Qing Zhong

Journal: Nature Chemical Biology

PubMed ID: 38212578

Doi: 10.1038/s41589-023-01512-1

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Towards detection of structurally-diverse glycated epitopes in native proteins: Single-chain antibody directed to non-A1c epitope in human haemoglobin

Authors: Miss Lucia Gaetani, Isabel Campos Pinto, Meng Li, Peter O'Connor, Susan Giorgi-Coll, Matthew Tyreman, Katherine L Rumary, James A Schouten, Paul Davis, Ann M Dixon

Journal: Mol Immunol

PubMed ID: 38181455

Doi: 10.1016/j.molimm.2023.12.008

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A general platform for targeting MHC-II antigens via a single loop

Authors: Haotian Du, Jingjia Liu, Kevin M Jude, Xinbo Yang, Ying Li, Braxton Bell, Hongli Yang, Audrey Kassardjian, Ali Mobedi, Udit Parekh, R Andres Parra Sperberg, Jean-Philippe Julien, Elizabeth D Mellins, K Christopher Garcia, Po-Ssu Huang

Journal: biorxiv

PubMed ID: 38352315

Doi: 10.1101/2024.01.26.577489

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PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease

Authors: Guangyu Zhou, Chen Zhang, Hui Peng, Xuesong Su, Qun Huang, Zixia Zhao, Guangyi Zhao

Journal: Mol Med

PubMed ID: 38200452

Doi: 10.1186/s10020-023-00759-7

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Structural biases in disordered proteins are prevalent in the cell

Authors: David Moses, Karina Guadalupe, Feng Yu, Eduardo Flores, Anthony R Perez, Ralph McAnelly, Nora M Shamoon, Gagandeep Kaur, Estefania Cuevas-Zepeda, Andrea D Merg, Erik W Martin, Alex S Holehouse, Shahar Sukenik

Journal: Nat Struct Mol Biol

PubMed ID: 38177684

Doi: 10.1038/s41594-023-01148-8

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Response to COVID-19 vaccination in patients on cancer therapy: Analysis in a SARS-CoV-2-naïve population

Authors: George Cavic, Andrew A Almonte, Sarah M Hicks, Teresa Neeman, Jo-Wai Wang, Sue Brew, Philip Y Choi, Ian Cockburn, Elizabeth E Gardiner, Desmond Yip, Aude M Fahrer, Yada Kanjanapan

Journal: Asia Pac J Clin Oncol

PubMed ID: 38221764

Doi: 10.1111/ajco.14047

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PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial

Authors: Francisco J Martinez, Michael White, Micheline Guillotte-Blisnick, Christèle Huon, Alix Boucharlat, Fabrice Agou, Patrick England, Jean Popovici, Mimi M Hou, Sarah E Silk, Jordan R Barrett, Carolyn M Nielsen, Jenny M Reimer, Paushali Mukherjee, Virander S Chauhan, Angela M Minassian, Simon J Draper, Chetan E Chitnis

Journal: npj Vaccines

PubMed ID: 38184681

Doi: 10.1038/s41541-023-00796-7

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PARP trapping is governed by the PARP inhibitor dissociation rate constant

Authors: Angelica A Gopal, Bianca Fernandez, Justin Delano, Ralph Weissleder, J Matthew Dubach

Journal: Cell Chem Biol

PubMed ID: 38262416

Doi: 10.1016/j.chembiol.2023.12.019

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Exploring a novel long-acting glucagon-like peptide-1 receptor agonist built on the albumin-binding domain and XTEN scaffolds

Authors: Yan Zhou, Jianhui Li, Guosheng Gao, Yafeng Li, Changzhen Zhang

Journal: Heliyon

PubMed ID: 38293540

Doi: 10.1016/j.heliyon.2024.e24340

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Comparative Study on the Immunogenicity of COVID-19 mRNA Vaccines in Patients Receiving Adjuvant and Palliative Chemotherapy

Authors: Hyun-Woo Choi, Younggon Jung, Uh Jin Kim, Sang-Cheol Lee, Jung Hye Kwon, Hyeonjong Kim, Sarah Kim, Yoonjung Lee, Hyun-Jung Shim, Sang-Hee Cho, Ik-Joo Chung, Eu Chang Hwang, Seung Ji Kang, Woo Kyun Bae, Seung-Jung Kee

Journal: Chonnam Med J

PubMed ID: 38304127

Doi: 10.4068/cmj.2024.60.1.69

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Improving and Streamlining Gene Editing in via Integration of Engineered Cas9 Protein

Authors: Baixi Zhang, Jiacan Cao

Journal: J Fungi (Basel)

PubMed ID: 38248972

Doi: 10.3390/jof10010063

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A metalloprotein nanoparticle scaffold co-delivers antigens and adjuvants with metal-enhanced STING activation for vaccination preventing viral infections

Authors: Jiexin Li , Qian Qiu , He Ren , Jingyu Zhang , Chen Zhang , Gengqi Liu , Boyang Sun , Bin Zheng , Jonathan F. Lovell , Yumiao Zhang

Journal: Nano Today

Doi: 10.1016/j.nantod.2024.102156

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Rapid production of chimeric silkworm/spider silk with improved mechanical properties by infection of nonpermissive Bombyx mori with recombinant AcMNPV harboring native-size of spidroin genes

Authors: Xiaolong Hu, Nan Li , Sicheng Guo, Min Zhu , Xing Zhang , Chonglong Wang , Chengliang Gong

Journal: Int J Biol Macromol .

PubMed ID: 38035957

Doi: 10.1016/j.ijbiomac.2023.128466.

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Impact of surface receptors TLR2, CR3, and FcγRIII on Rhodococcus equi phagocytosis and intracellular survival in macrophages

Authors: Bibiana Petri da Silveira , Rola Barhoumi , Jocelyne M Bray , Hannah M Cole-Pfeiffer , Cory J Mabry , Robert C Burghardt , Noah D Cohen, Angela I Bordin

Journal: Immunity

PubMed ID: 38018994

Doi: 10.1128/iai.00383-23

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The HIV capsid mimics karyopherin engagement of FG-nucleoporins

Authors: C. F. Dickson, S. Hertel, A. J. Tuckwell, N. Li, J. Ruan, S. C. Al-Izzi, N. Ariotti, E. Sierecki, Y. Gambin, R. G. Morris, G. J. Towers, T. Böcking & D. A. Jacques

Journal: Nature

PubMed ID: 38267582

Doi: 10.1038/s41586-023-06969-7

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The cryo-EM structure of homotetrameric attachment glycoprotein from langya henipavirus

Authors: Yingying Guo , Songyue Wu , Wenting Li , Haonan Yang , Tianhao Shi , Bin Ju , Zheng Zhang , Renhong Yan

Journal: Nat Commun

PubMed ID: 38280880

Doi: 10.1038/s41467-024-45202-5

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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

Authors: Eike-Christian Wamhoff , Larance Ronsard , Jared Feldman , Grant A Knappe , Blake M Hauser , Anna Romanov , James Brett Case , Shilpa Sanapala , Evan C Lam , Kerri J St Denis , Julie Boucau , Amy K Barczak , Alejandro B Balazs , Michael S Diamond , Aaron G Schmidt , Daniel Lingwood , Mark Bathe

Journal: Nat Commun

PubMed ID: 38291019

Doi: 10.1038/s41467-024-44869-0

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Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy

Authors: Binh An Nguyen , Virender Singh , Shumaila Afrin , Anna Yakubovska , Lanie Wang , Yasmin Ahmed , Rose Pedretti , Maria Del Carmen Fernandez-Ramirez , Preeti Singh , Maja Pękała , Luis O Cabrera Hernandez , Siddharth Kumar , Andrew Lemoff , Roman Gonzalez-Prieto , Michael R Sawaya , David S Eisenberg , Merrill Douglas Benson , Lorena Saelices

Journal: Nat Commun

PubMed ID: 38233397

Doi: 10.1038/s41467-024-44820-3

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STYXL1 regulates CCT complex assembly and flagellar tubulin folding in sperm formation

Authors: Yu Chen , Mengjiao Luo , Haixia Tu , Yaling Qi , Yueshuai Guo , Xiangzheng Zhang , Yiqiang Cui , Mengmeng Gao , Xin Zhou , Tianyu Zhu , Hui Zhu , Chenghao Situ , Yan Li , Xuejiang Guo

Journal: Nat Commun

PubMed ID: 38168070

Doi: 10.1038/s41467-023-44337-1

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Cryo-EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH

Authors: Niraj Kumar , Shivani Sharma , Prem S Kaushal

Journal: Nat Commun

PubMed ID: 38245551

Doi: 10.1038/s41467-024-44879-y

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Biomimetic Control over Bimetallic Nanoparticle Structure and Activity via Peptide Capping Ligand Sequence

Authors: Maichong Xie, Ryuichi Shimogawa, Yang Liu, Lihua Zhang, Alexandre C. Foucher, Prahlad K. Routh, Eric A. Stach, Anatoly I. Frenkel*, and Marc R. Knecht

Journal: ACS Nano

PubMed ID: 38227802

Doi: 10.1021/acsnano.3c10016

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Cross-feeding promotes heterogeneity within yeast cell populations

Authors: Kevin K Y Hu, Ankita Suri, Geoff Dumsday, Victoria S Haritos

Journal: Nat Commun

PubMed ID: 38200012

Doi: 10.1038/s41467-023-44623-y

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Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake

Authors: Kazuki Takeda, Taki Saito, Sakura Sasaki, Akifumi Eguchi, Makoto Sugiyama, Saeka Eto, Kio Suzuki, Ryo Kamata

Journal: Toxics

PubMed ID: 38251008

Doi: 10.3390/toxics12010052

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Single-Molecule Analysis of SARS-CoV-2 Double-Stranded Polynucleotides Using Solid-State Nanopore with AI-Assisted Detection and Classification: Implications for Understanding Disease Severity

Authors: Ibrar Alam, Thitikorn Boonkoom, Harit Pitakjakpipop, Poramin Boonbanjong, Kawin Loha, Thanaya Saeyang, Jarunee Vanichtanankul, Deanpen Japrung

Journal: ACS Appl Bio Mater

PubMed ID: 38194666

Doi: 10.1021/acsabm.3c00998

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Safety, Immunogenicity, and Mechanism of a Rotavirus mRNA-LNP Vaccine in Mice

Authors: Chenxing Lu, Yan Li, Rong Chen, Xiaoqing Hu, Qingmei Leng, Xiaopeng Song, Xiaochen Lin, Jun Ye, Jinlan Wang, Jinmei Li, Lida Yao, Xianqiong Tang, Xiangjun Kuang, Guangming Zhang, Maosheng Sun, Yan Zhou, Hongjun Li

Journal: Viruses

PubMed ID: 38399987

Doi: 10.3390/v16020211

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Efficient treatment of colon cancer with codelivery of TRAIL and imatinib by liposomes

Authors: Rongrong Fu, Rui Chang, Andong Peng, Changshun Feng, Weifan Zhu, Yi Chen, Xue Tian, Rui Wang, Hui Yan, Dianlong Jia, Jun Li

Journal: Pharm Dev Technol

PubMed ID: 38230653

Doi: 10.1080/10837450.2024.2301763

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Structural insights into the activation and inhibition of CXC chemokine receptor 3

Authors: Haizhan Jiao, Bin Pang, Aijun Liu, Qiang Chen, Qi Pan, Xiankun Wang, Yunong Xu, Ying-Chih Chiang, Ruobing Ren, Hongli Hu

Journal: Nat Struct Mol Biol

PubMed ID: 38177682

Doi: 10.1038/s41594-023-01175-5

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Host protein EPCAM interacting with EtMIC8-EGF is essential for attachment and invasion of Eimeria tenella in chickens

Authors: Lingyu Sun, Chao Li, Ningning Zhao, Bingxiang Wang, Hongmei Li, Hairong Wang, Xiao Zhang, Xiaomin Zhao

Journal: Microb Pathog

PubMed ID: 38281605

Doi: 10.1016/j.micpath.2024.106549

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Engineering for Sustainable Production of the Pomegranate Seed Oil-Derived Punicic Acid

Authors: Kaifeng Wang, Yueyue Zhou, Lizhen Cao, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji

Journal: J Agric Food Chem

PubMed ID: 38282297

Doi: 10.1021/acs.jafc.3c08718

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Up-regulation of lncRNA WT1-AS ameliorates Aβ-stimulated neuronal injury through modulation of miR-186-5p/CCND2 axis in Alzheimer's disease

Authors: Yun Tang, Xiaojiu Zhang, Shihui Wang, Lu Liu, Qing Wang, Yufeng Liu, Yadong Yu, Qijin Zhai

Journal: Cell Mol Biol (Noisy-le-grand)

PubMed ID: 38372094

Doi: 10.14715/cmb/2024.70.1.27

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Assessing the protection elicited by virus-like particles expressing the RSV pre-fusion F and tandem repeated G proteins against RSV rA2 line19F infection in mice

Authors: Min-Ju Kim, Ki Back Chu, Su-Hwa Lee, Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Eun-Kyung Moon, Fu-Shi Quan

Journal: Respir Res

PubMed ID: 38178222

Doi: 10.1186/s12931-023-02641-w

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Chronic cortisol stimulation enhances hypothalamus-specific enrichment of metabolites in the rainbow trout brain

Authors: Ayelén M Blanco, Femilarani Antomagesh, Sara Comesaña, José L Soengas, Mathilakath M Vijayan

Journal: Am J Physiol Endocrinol Metab

PubMed ID: 38294699

Doi: 10.1152/ajpendo.00410.2023

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Spatial and Single-Cell Transcriptomics Reveal a Cancer-Associated Fibroblast Subset in HNSCC That Restricts Infiltration and Antitumor Activity of CD8+ T Cells

Authors: Chuwen Li, Haiyan Guo, Peisong Zhai, Ming Yan, Chun Liu, Xiaoning Wang, Chaoji Shi, Jiang Li, Tong Tong, Zhiyuan Zhang, Hailong Ma, Jianjun Zhang

Journal: Cancer Res

PubMed ID: 37930937

Doi: 10.1158/0008-5472.CAN-23-1448

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Tuning plasmid DNA amounts for cost-effective transfections of mammalian cells: when less is more

Authors: Aida Carreño, Rubén Guerrero-Yagüe, Enriqueta Casal, Rosa Mendoza, José Luis Corchero

Journal: Appl Microbiol Biotechnol

PubMed ID: 38212965

Doi: 10.1007/s00253-024-13003-x

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Remodelling the inguinal adipose sensory system to switch on the furnace: Electroacupuncture stimulation induces brown adipose thermogenesis

Authors: Mengjiang Lu , Ziwei Yu , Xingyu Yang , Li An , Xinyue Jing , Tiancheng Xu , Mengqian Yuan , Bin Xu , Zhi Yu

Journal: Diabetes Obes Metab .

PubMed ID: 38229447

Doi: 10.1111/dom.15444

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Tomato-made edible COVID-19 vaccine TOMAVAC induces neutralizing IgGs in the blood sera of mice and humans

Authors: Zabardast T Buriev, Shukhrat E Shermatov, Dilshod E Usmanov, Mukhammadjon K Mirzakhmedov, Khurshida A Ubaydullaeva, Venera S Kamburova, Bakhtiyor K Rakhmanov, Mirzakamol S Ayubov, Adkham N Abdullaev

Journal: Front Nutr

PubMed ID: 38260078

Doi: 10.3389/fnut.2023.1275307

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GDF15 linked to maternal risk of nausea and vomiting during pregnancy

Authors: M Fejzo # 1, N Rocha Cimino # 2, S M Lockhart # 2, C J Petry # 2, R G Kay 2 3, K Burling 2 4, P Barker 2 4, A L George 3, N Yasara 5, A Premawardhena 6 7, S Gong 8 9, E Cook 8, D Rimmington 2, K Rainbow 2, D J Withers 2, V Cortessis 10, P M Mullin 11, K W MacGibbon 12, E Jin, A Kam, A Campbell , O Polasek , G Tzoneva , F M Gribble , G S H Yeo , B Y H Lam , V Saudek, I A Hughes, K K Ong, J R B Perry , A Sutton Cole , M Baumgarten , P Welsh , N Sattar , G C S Smith , D S Charnock-Jones, A P Coll, C L Meek Mettananda , C Hayward, N Mancuso , S O'Rahilly

Journal: Nature

PubMed ID: 38092039

Doi: 10.1038/s41586-023-06921-9

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Smart lattice light-sheet microscopy for imaging rare and complex cellular events

Authors: Yu Shi , Jimmy S Tabet , Daniel E Milkie , Timothy A Daugird , Chelsea Q Yang , Alex T Ritter , Andrea Giovannucci , Wesley R Legant

Journal: Nat Methods

PubMed ID: 38167656

Doi: 10.1038/s41592-023-02126-0

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Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice

Authors: Kaili Fu 1, Alvin Ho Kwan Cheung 2, Chi Chun Wong 1, Weixin Liu 1, Yunfei Zhou 1, Feixue Wang 1, Pingmei Huang 1, Kai Yuan 1, Olabisi Oluwabukola Coker 1, Yasi Pan 1, Danyu Chen 1, Nga Man Lam 3, Mengxue Gao 4, Xiang Zhang 1, He Huang 4, Ka Fai To 2, Joseph Jao Yiu Sung 5, Jun Yu

Journal: Cell

PubMed ID: 38295787

Doi: 10.1016/j.cell.2024.01.004

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Complement receptor 1 is the human erythrocyte receptor for erythrocyte binding protein

Authors: Seong-Kyun Lee, Cécile Crosnier, Paola Carolina Valenzuela-Leon, Brian L P Dizon, John P Atkinson, Jianbing Mu, Gavin J Wright, Eric Calvo, Karthigayan Gunalan, Louis H Miller

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38261617

Doi: 10.1073/pnas.2316304121

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Multidimensional Optimization of for Carotenoid Overproduction

Authors: Jian Fan, Yang Zhang, Wenhao Li, Zhizhen Li, Danli Zhang, Qiwen Mo, Mingfeng Cao, Jifeng Yuan

Journal: Biodes Res

PubMed ID: 38213763

Doi: 10.34133/bdr.0026

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The Development of a Rabies Virus-Vectored Vaccine against , Targeting BBI39

Authors: Shantel Rios, Bibek Bhattachan, Kruthi Vavilikolanu, Chrysoula Kitsou, Utpal Pal, Matthias J Schnell

Journal: Vaccines (Basel)

PubMed ID: 38250891

Doi: 10.3390/vaccines12010078

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