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Estimation of the Parasitic Burden of Soil-Transmitted Helminths Among Pregnant Women in the Maharashtra State of India Using qPCR: A Community-Based Study

Authors: Shilpa Gaidhane, Abhay Gaidhane, Mahalaqua Nazli Khatib, Shital Telrandhe, Manoj Patil, Deepak Saxena, Pankaj Bhardwaj, Sonali Choudhari, Quazi S Zahiruddin

Journal: Indian J Community Med

PubMed ID: 38425985

Doi: 10.4103/ijcm.ijcm_249_23

Products & Services: PCR Cloning and Subcloning

KDM6A Demethylase Regulates Renal Sodium Excretion and Blood Pressure

Authors: Xiaobin Han, Leah Akinseye, Zhongjie Sun

Journal: Hypertension

PubMed ID: 38164755

Doi: 10.1161/HYPERTENSIONAHA.123.22026

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from

Authors: Fredrik Leo, Rolf Lood, Kristina A Thomsson, Jonas Nilsson, Gunnel Svensäter, Claes Wickström

Journal: Front Microbiol

PubMed ID: 38304711

Doi: 10.3389/fmicb.2024.1340109

Products & Services: Molecular Biology Reagents

Functionally coherent transcriptional responses of Jatropha curcas and Pseudomonas fragi for rhizosphere mediated degradation of pyrene

Authors: L Paikhomba Singha, K Malabika Singha, Piyush Pandey

Journal: Sci Rep

PubMed ID: 38200308

Doi: 10.1038/s41598-024-51581-y

Products & Services: PCR Cloning and Subcloning

A Mixture of T-Cell Epitope Peptides Derived from Human Respiratory Syncytial Virus F Protein Conferred Protection in DR1-TCR Tg Mice

Authors: Hong Guo, Yang Song, Hai Li, Hongqiao Hu, Yuqing Shi, Jie Jiang, Jinyuan Guo, Lei Cao, Naiying Mao, Yan Zhang

Journal: Vaccines (Basel)

PubMed ID: 38250890

Doi: 10.3390/vaccines12010077

Products & Services: Catalog Peptides

Safety, Immunogenicity, and Mechanism of a Rotavirus mRNA-LNP Vaccine in Mice

Authors: Chenxing Lu, Yan Li, Rong Chen, Xiaoqing Hu, Qingmei Leng, Xiaopeng Song, Xiaochen Lin, Jun Ye, Jinlan Wang, Jinmei Li, Lida Yao, Xianqiong Tang, Xiangjun Kuang, Guangming Zhang, Maosheng Sun, Yan Zhou, Hongjun Li

Journal: Viruses

PubMed ID: 38399987

Doi: 10.3390/v16020211

Products & Services: Molecular Biology Reagents

Efficient treatment of colon cancer with codelivery of TRAIL and imatinib by liposomes

Authors: Rongrong Fu, Rui Chang, Andong Peng, Changshun Feng, Weifan Zhu, Yi Chen, Xue Tian, Rui Wang, Hui Yan, Dianlong Jia, Jun Li

Journal: Pharm Dev Technol

PubMed ID: 38230653

Doi: 10.1080/10837450.2024.2301763

Products & Services: Proteins, Expression, Isolation and Analysis

Host protein EPCAM interacting with EtMIC8-EGF is essential for attachment and invasion of Eimeria tenella in chickens

Authors: Lingyu Sun, Chao Li, Ningning Zhao, Bingxiang Wang, Hongmei Li, Hairong Wang, Xiao Zhang, Xiaomin Zhao

Journal: Microb Pathog

PubMed ID: 38281605

Doi: 10.1016/j.micpath.2024.106549

Products & Services: Proteins, Expression, Isolation and Analysis

HCMV IE1/IE1mut Therapeutic Vaccine Induces Tumor Regression via Intratumoral Tertiary Lymphoid Structure Formation and Peripheral Immunity Activation in Glioblastoma Multiforme

Authors: Xiaoli Yang, Shasha Jiang, Fengjun Liu, Zonghui Li, Wenxuan Liu, Xianjuan Zhang, Fulong Nan, Jun Li, Meng Yu, Yunyang Wang, Bin Wang

Journal: Mol Neurobiol

PubMed ID: 38261253

Doi: 10.1007/s12035-024-03937-8

Products & Services: Recombinant Proteins

Engineering for Sustainable Production of the Pomegranate Seed Oil-Derived Punicic Acid

Authors: Kaifeng Wang, Yueyue Zhou, Lizhen Cao, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji

Journal: J Agric Food Chem

PubMed ID: 38282297

Doi: 10.1021/acs.jafc.3c08718

Products & Services: Gene Synthesis

Mitochondrial Homeostasis Regulating Mitochondrial Number and Morphology Is a Distinguishing Feature of Skeletal Muscle Fiber Types in Marine Teleosts

Authors: Busu Li, Huan Wang, Xianghui Zeng, Shufang Liu, Zhimeng Zhuang

Journal: Int J Mol Sci

PubMed ID: 38338790

Doi: 10.3390/ijms25031512

Products & Services: Proteins, Expression, Isolation and Analysis

Capsid protein mediated evasion of IRAK1-dependent signalling is essential to Sindbis virus neuroinvasion and virulence in mice

Authors: V Douglas Landers, Milton Thomas, Cierra M Isom, Deepa Karki, Kevin J Sokoloski

Journal: Emerg Microbes Infect

PubMed ID: 38164715

Doi: 10.1080/22221751.2023.2300452

Products & Services: Proteins, Expression, Isolation and Analysis

Chronic cortisol stimulation enhances hypothalamus-specific enrichment of metabolites in the rainbow trout brain

Authors: Ayelén M Blanco, Femilarani Antomagesh, Sara Comesaña, José L Soengas, Mathilakath M Vijayan

Journal: Am J Physiol Endocrinol Metab

PubMed ID: 38294699

Doi: 10.1152/ajpendo.00410.2023

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Assessing the protection elicited by virus-like particles expressing the RSV pre-fusion F and tandem repeated G proteins against RSV rA2 line19F infection in mice

Authors: Min-Ju Kim, Ki Back Chu, Su-Hwa Lee, Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Eun-Kyung Moon, Fu-Shi Quan

Journal: Respir Res

PubMed ID: 38178222

Doi: 10.1186/s12931-023-02641-w

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A metalloprotein nanoparticle scaffold co-delivers antigens and adjuvants with metal-enhanced STING activation for vaccination preventing viral infections

Authors: Jiexin Li , Qian Qiu , He Ren , Jingyu Zhang , Chen Zhang , Gengqi Liu , Boyang Sun , Bin Zheng , Jonathan F. Lovell , Yumiao Zhang

Journal: Nano Today

Doi: 10.1016/j.nantod.2024.102156

Products & Services: Proteins, Expression, Isolation and Analysis

Rapid production of chimeric silkworm/spider silk with improved mechanical properties by infection of nonpermissive Bombyx mori with recombinant AcMNPV harboring native-size of spidroin genes

Authors: Xiaolong Hu, Nan Li , Sicheng Guo, Min Zhu , Xing Zhang , Chonglong Wang , Chengliang Gong

Journal: Int J Biol Macromol .

PubMed ID: 38035957

Doi: 10.1016/j.ijbiomac.2023.128466.

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CGI1746 targets σ1R to modulate ferroptosis through mitochondria-associated membranes

Authors: Zili Zhang, Hong Zhou, Wenjia Gu, Yuehan Wei, Shan Mou, Youjun Wang, Jing Zhang & Qing Zhong

Journal: Nature Chemical Biology

PubMed ID: 38212578

Doi: 10.1038/s41589-023-01512-1

Products & Services: Recombinant Antibody Expression

A novel starch-active lytic polysaccharide monooxygenase discovered with bioinformatics screening and its application in textile desizing

Authors: Meijuan Zhang, Xiaoping Fu, Rongrong Gu, Bohua Zhao, Xingya Zhao, Hui Song, Hongchen Zheng, Jianyong Xu, Wenqin Bai

Journal: BMC Biotechnol

PubMed ID: 38200466

Doi: 10.1186/s12896-023-00826-1

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Towards detection of structurally-diverse glycated epitopes in native proteins: Single-chain antibody directed to non-A1c epitope in human haemoglobin

Authors: Miss Lucia Gaetani, Isabel Campos Pinto, Meng Li, Peter O'Connor, Susan Giorgi-Coll, Matthew Tyreman, Katherine L Rumary, James A Schouten, Paul Davis, Ann M Dixon

Journal: Mol Immunol

PubMed ID: 38181455

Doi: 10.1016/j.molimm.2023.12.008

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Comparative immunogenicity and neutralizing antibody responses post heterologous vaccination with CoronaVac (Sinovac) and Vaxzevria (AstraZeneca) in HIV-infected patients with varying CD4+ T lymphocyte counts

Authors: Sorawit Chittrakarn, Pisud Siripaitoon, Sarunyou Chusri, Siripen Kanchanasuwan, Boonsri Charoenmak, Thanaporn Hortiwakul, Phaiwon Kantikit, Narongdet Kositpantawong

Journal: Hum Vaccin Immunother

PubMed ID: 38297904

Doi: 10.1080/21645515.2024.2309734

Products & Services: Molecular Biology Reagents

PARP trapping is governed by the PARP inhibitor dissociation rate constant

Authors: Angelica A Gopal, Bianca Fernandez, Justin Delano, Ralph Weissleder, J Matthew Dubach

Journal: Cell Chem Biol

PubMed ID: 38262416

Doi: 10.1016/j.chembiol.2023.12.019

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Exploring a novel long-acting glucagon-like peptide-1 receptor agonist built on the albumin-binding domain and XTEN scaffolds

Authors: Yan Zhou, Jianhui Li, Guosheng Gao, Yafeng Li, Changzhen Zhang

Journal: Heliyon

PubMed ID: 38293540

Doi: 10.1016/j.heliyon.2024.e24340

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Improving and Streamlining Gene Editing in via Integration of Engineered Cas9 Protein

Authors: Baixi Zhang, Jiacan Cao

Journal: J Fungi (Basel)

PubMed ID: 38248972

Doi: 10.3390/jof10010063

Products & Services: Molecular Biology Reagents

Tuning plasmid DNA amounts for cost-effective transfections of mammalian cells: when less is more

Authors: Aida Carreño, Rubén Guerrero-Yagüe, Enriqueta Casal, Rosa Mendoza, José Luis Corchero

Journal: Appl Microbiol Biotechnol

PubMed ID: 38212965

Doi: 10.1007/s00253-024-13003-x

Products & Services: Molecular Biology Reagents

Remodelling the inguinal adipose sensory system to switch on the furnace: Electroacupuncture stimulation induces brown adipose thermogenesis

Authors: Mengjiang Lu , Ziwei Yu , Xingyu Yang , Li An , Xinyue Jing , Tiancheng Xu , Mengqian Yuan , Bin Xu , Zhi Yu

Journal: Diabetes Obes Metab .

PubMed ID: 38229447

Doi: 10.1111/dom.15444

Products & Services: Proteins, Expression, Isolation and Analysis

LL‐37_Renalexin hybrid peptide exhibits antimicrobial activity at lower MICs than its counterpart single peptides

Authors: Julius Kwesi Narh , Nestor G Casillas-Vega , Xristo Zarate

Journal: Appl Microbiol Biotechnol .

PubMed ID: 38229302

Doi: 10.1007/s00253-023-12887-5

Products & Services: Gene Synthesis

High-Yield Expression and Purification of Scygonadin, an Antimicrobial Peptide, Using the Small Metal-Binding Protein SmbP

Authors: Jessica J. Gomez-Lugo 1 , Nestor G. Casillas-Vega , Alma Gomez-Loredo , Isaias Balderas-Renteria and Xristo Zarate

Journal: Microorganisms

Doi: 10.3390/microorganisms12020278

Products & Services: Gene Synthesis

Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain

Authors: Yanqun Wang, Zhaoyong Zhang, Minnan Yang, Xinyi Xiong, Qihong Yan, Lei Cao, Peilan Wei, Yuting Zhang, Lu Zhang, Kexin Lv, Jiantao Chen, Xuesong Liu, Xiaochu Zhao, Juxue Xiao, Shengnan Zhang, Airu Zhu, Mian Gan, Jingjun Zhang, Ruoxi Cai, Jianfen Zhuo, Yanjun Zhang, Haiyue Rao, Bin Qu, Yuanyuan Zhang, Lei Chen, Jun Dai, Linling Cheng, Qingtao Hu, Yaoqing Chen, Huibin Lv, Ray T Y So, Malik Peiris, Jingxian Zhao, Xiaoqing Liu, Chris Ka Pun Mok, Xiangxi Wang, Jincun Zhao

Journal: Cell Rep

PubMed ID: 38175758

Doi: 10.1016/j.celrep.2023.113653

Products & Services: Recombinant Proteins

The Development of a Rabies Virus-Vectored Vaccine against , Targeting BBI39

Authors: Shantel Rios, Bibek Bhattachan, Kruthi Vavilikolanu, Chrysoula Kitsou, Utpal Pal, Matthias J Schnell

Journal: Vaccines (Basel)

PubMed ID: 38250891

Doi: 10.3390/vaccines12010078

Products & Services: Recombinant Proteins

factor H-binding proteins are not required for serum resistance and infection in mammals

Authors: Nicholas A Cramer, Kalya M Socarras, Joshua Earl, Garth D Ehrlich, Richard T Marconi

Journal: Infect Immun

PubMed ID: 38289123

Doi: 10.1128/iai.00529-23

Products & Services: Codon Optimization

Structural role of K224 in taniborbactam inhibition of NDM-1

Authors: Daisuke Ono, Maria F Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego M Moreno, Alejandro J Vila, Robert A Bonomo

Journal: Antimicrob Agents Chemother

PubMed ID: 38174924

Doi: 10.1128/aac.01332-23

Products & Services: Molecular Biology Reagents

Comparison of mouse models of microbial experience reveals differences in microbial diversity and response to vaccination

Authors: Autumn E Sanders, Henriette Arnesen, Frances K Shepherd, Dira S Putri, Jessica K Fiege, Mark J Pierson, Shanley N Roach, Harald Carlsen, David Masopust, Preben Boysen, Ryan A Langlois

Journal: mSphere

PubMed ID: 38286428

Doi: 10.1128/msphere.00654-23

Products & Services: Recombinant Proteins

Antibody reactive immunomes of and are diverse and defined by conformational antigenic determinants

Authors: Tian Luo, Jignesh G Patel, Xiaofeng Zhang, Jere W McBride

Journal: Front Cell Infect Microbiol

PubMed ID: 38264730

Doi: 10.3389/fcimb.2023.1321291

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Recombinantly expressed virus-like particles (VLPs) of canine circovirus for development of an indirect ELISA

Authors: Alison Neef, Babu Kanti Nath, Tridip Das, Daniel Luque, Jade K Forwood, Shane R Raidal, Shubhagata Das

Journal: Vet Res Commun

PubMed ID: 38163840

Doi: 10.1007/s11259-023-10290-z

Products & Services: Gene Synthesis

ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism

Authors: Edrees H Rashan, Abigail K Bartlett, Daven B Khana, Jingying Zhang, Raghav Jain, Andrew J Smith, Zakery N Baker, Taylor Cook, Alana Caldwell, Autumn R Chevalier, Brian F Pfleger, Peng Yuan, Daniel Amador-Noguez, Judith A Simcox, David J Pagliarini

Journal: biorxiv

PubMed ID: 38260250

Doi: 10.1101/2024.01.09.574893

Products & Services: Codon Optimization

Affinity-assisted covalent self-assembly of PduQ-SpyTag and Nox-SpyCatcher to construct multi-enzyme complexes on the surface of magnetic microsphere modified with chelated Ni

Authors: Mianxing Luo, Meng Zhang, Changbiao Chi, Guo Chen

Journal: Int J Biol Macromol

PubMed ID: 38218263

Doi: 10.1016/j.ijbiomac.2024.129365

Products & Services: Gene Synthesis

Comparative Analysis of Two NNMT Bisubstrate Inhibitors through Chemoproteomic Studies: Uncovering the Role of Unconventional SAM Analogue Moiety for Improved Selectivity

Authors: Ying Meng, Iredia D Iyamu, Noha A M Ahmed, Rong Huang

Journal: ACS Chem Biol

PubMed ID: 38181447

Doi: 10.1021/acschembio.3c00531

Products & Services: Proteins, Expression, Isolation and Analysis

A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways

Authors: Zhibin Zhang , Xi Lin , Ling Wei , Yiran Wu , Lu Xu , Lijie Wu , Xiaohu Wei , Suwen Zhao, Xiangjia Zhu , Fei Xu

Journal: Cell Discov .

PubMed ID: 38182578

Doi: s41421-023-00627-y

Products & Services: Codon Optimization

Tomato-made edible COVID-19 vaccine TOMAVAC induces neutralizing IgGs in the blood sera of mice and humans

Authors: Zabardast T Buriev, Shukhrat E Shermatov, Dilshod E Usmanov, Mukhammadjon K Mirzakhmedov, Khurshida A Ubaydullaeva, Venera S Kamburova, Bakhtiyor K Rakhmanov, Mirzakamol S Ayubov, Adkham N Abdullaev

Journal: Front Nutr

PubMed ID: 38260078

Doi: 10.3389/fnut.2023.1275307

Products & Services: Gene Synthesis

Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice

Authors: Kaili Fu 1, Alvin Ho Kwan Cheung 2, Chi Chun Wong 1, Weixin Liu 1, Yunfei Zhou 1, Feixue Wang 1, Pingmei Huang 1, Kai Yuan 1, Olabisi Oluwabukola Coker 1, Yasi Pan 1, Danyu Chen 1, Nga Man Lam 3, Mengxue Gao 4, Xiang Zhang 1, He Huang 4, Ka Fai To 2, Joseph Jao Yiu Sung 5, Jun Yu

Journal: Cell

PubMed ID: 38295787

Doi: 10.1016/j.cell.2024.01.004

Products & Services: Gene Synthesis

Smart lattice light-sheet microscopy for imaging rare and complex cellular events

Authors: Yu Shi , Jimmy S Tabet , Daniel E Milkie , Timothy A Daugird , Chelsea Q Yang , Alex T Ritter , Andrea Giovannucci , Wesley R Legant

Journal: Nat Methods

PubMed ID: 38167656

Doi: 10.1038/s41592-023-02126-0

Products & Services: PCR Cloning and Subcloning

GDF15 linked to maternal risk of nausea and vomiting during pregnancy

Authors: M Fejzo # 1, N Rocha Cimino # 2, S M Lockhart # 2, C J Petry # 2, R G Kay 2 3, K Burling 2 4, P Barker 2 4, A L George 3, N Yasara 5, A Premawardhena 6 7, S Gong 8 9, E Cook 8, D Rimmington 2, K Rainbow 2, D J Withers 2, V Cortessis 10, P M Mullin 11, K W MacGibbon 12, E Jin, A Kam, A Campbell , O Polasek , G Tzoneva , F M Gribble , G S H Yeo , B Y H Lam , V Saudek, I A Hughes, K K Ong, J R B Perry , A Sutton Cole , M Baumgarten , P Welsh , N Sattar , G C S Smith , D S Charnock-Jones, A P Coll, C L Meek Mettananda , C Hayward, N Mancuso , S O'Rahilly

Journal: Nature

PubMed ID: 38092039

Doi: 10.1038/s41586-023-06921-9

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Circ_0087199 depletion attenuates lipopolysaccharides-induced human periodontal ligament cell injury through the miR-527/TLR4 axis

Authors: Jing Wang , Na Huo , Chuan Cai , Yu Zhang, Rui Xiao

Journal: Immunity

PubMed ID: 38270303

Doi: 10.1002/iid3.1153

Complement receptor 1 is the human erythrocyte receptor for erythrocyte binding protein

Authors: Seong-Kyun Lee, Cécile Crosnier, Paola Carolina Valenzuela-Leon, Brian L P Dizon, John P Atkinson, Jianbing Mu, Gavin J Wright, Eric Calvo, Karthigayan Gunalan, Louis H Miller

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38261617

Doi: 10.1073/pnas.2316304121

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Multidimensional Optimization of for Carotenoid Overproduction

Authors: Jian Fan, Yang Zhang, Wenhao Li, Zhizhen Li, Danli Zhang, Qiwen Mo, Mingfeng Cao, Jifeng Yuan

Journal: Biodes Res

PubMed ID: 38213763

Doi: 10.34133/bdr.0026

Products & Services: PCR Cloning and Subcloning

A conserved protein inhibitor brings under check the activity of RNase E in cyanobacteria

Authors: Su-Juan Liu, Gui-Ming Lin, Yu-Qi Yuan, Wenli Chen, Ju-Yuan Zhang, Cheng-Cai Zhang

Journal: Nucleic Acids Res

PubMed ID: 38000383

Doi: 10.1093/nar/gkad1094

Products & Services: Proteins, Expression, Isolation and Analysis

Pharmacokinetic Analyses of a Lipid Nanoparticle-Encapsulated mRNA-Encoded Antibody against Rift Valley Fever Virus

Authors: Shuo Wang, Ziling Zhu, Jianmin Li

Journal: Mol Pharm

PubMed ID: 38295278

Doi: 10.1021/acs.molpharmaceut.3c01016

Products & Services: Proteins, Expression, Isolation and Analysis

Long chain capsaicin analogues synthetized by CALB-CLEAs show cytotoxicity on glioblastoma cell lines

Authors: Tania Diaz-Vidal, Vicente Paúl Armenta-Pérez, Luis Carlos Rosales-Rivera, Georgina Cristina Basulto-Padilla, Raúl Balam Martínez-Pérez, Juan Carlos Mateos-Díaz, Yanet K Gutiérrez-Mercado, Alejandro A Canales-Aguirre, Jorge A Rodríguez

Journal: Appl Microbiol Biotechnol

PubMed ID: 38217255

Doi: 10.1007/s00253-023-12856-y

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Functional characterization of the dimeric form of PDGF-derived fusion peptide fabricated based on theoretical arguments

Authors: Maryam Sadeghi-Ardebili, Sadegh Hasannia, Bahareh Dabirmanesh, Ramazan Ali Khavari-Nejad

Journal: Sci Rep

PubMed ID: 38200288

Doi: 10.1038/s41598-024-51707-2

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A small-molecule activation mechanism that directly opens the KCNQ2 channel

Authors: Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiangtao Guo, Qiansen Zhang, Huaiyu Yang

Journal: Nat Chem Biol

PubMed ID: 38167918

Doi: 10.1038/s41589-023-01515-y

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Ewing Sarcoma Related protein 1 recognizes R-loops by binding DNA forks

Authors: Michelle A Lay, Valery F Thompson, Ajibola D Adelakun, Jacob C Schwartz

Journal: biorxiv

PubMed ID: 38293191

Doi: 10.1101/2024.01.20.576463

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The adc1 knockout with proC overexpression in Synechocystis sp PCC 6803 induces a diversion of acetyl-CoA to produce more polyhydroxybutyrate

Authors: Suthira Utharn, Saowarath Jantaro

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 38218963

Doi: 10.1186/s13068-024-02458-9

Products & Services: Proteins, Expression, Isolation and Analysis

A glycoside hydrolase 30 protein BpXynC of Bacillus paralicheniformis NMSW12 recognized as A MAMP triggers plant immunity response

Authors: Chenjie Yu, Xiaoli Liang, Yan Song, Qurban Ali, Xihao Yang, Linli Zhu, Qin Gu, Vladislav Kuptsov, Emilia Kolomiets, Huijun Wu, Xuewen Gao

Journal: Int J Biol Macromol

PubMed ID: 38286384

Doi: 10.1016/j.ijbiomac.2024.129750

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TMEM219 regulates the transcription factor expression and proliferation of beta cells

Authors: Francesca D'Addio, Emma Assi, Anna Maestroni, Giada Rossi, Vera Usuelli, Adriana Petrazzuolo, Marta Nardini, Cristian Loretelli, Moufida Ben Nasr, Paolo Fiorina

Journal: Front Endocrinol (Lausanne)

PubMed ID: 38318298

Doi: 10.3389/fendo.2024.1306127

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A novel strategy for an anti-idiotype vaccine: nanobody mimicking neutralization epitope of porcine circovirus type 2

Authors: Yingying Deng, Yamin Sheng, Guixi Zhang, Yani Sun, Lei Wang, Pinpin Ji, Jiahong Zhu, Gang Wang, Baoyuan Liu, En-Min Zhou, Xuehui Cai, Yabin Tu, Julian A Hiscox, James P Stewart, Yang Mu, Qin Zhao

Journal: J Virol

PubMed ID: 38271227

Doi: 10.1128/jvi.01650-23

Products & Services: Proteins, Expression, Isolation and Analysis

Improved detection sensitivity of anti-PRV variant antibodies through preparation of anti-gB and anti-gE monoclonal antibodies and development of blocking ELISAs

Authors: Zhenyang Guo, Hu Xu, Siyu Zhang, Haonan Kang, Chao Li, Qi Sun, Jing Zhao, Jinhao Li, Guohui Zhou, Qian Wang, Lirun Xiang, Yandong Tang, Huairan Liu, Chaoliang Leng, Tongqing An, Xuehui Cai, Zhijun Tian, Hongliang Zhang, Jinmei Peng

Journal: Int J Biol Macromol

PubMed ID: 38219937

Doi: 10.1016/j.ijbiomac.2024.129425

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ETHYLENE RESPONSE FACTOR 070 inhibits flowering in Pak-choi by indirectly impairing BcLEAFY expression

Authors: Zhanghong Yu , Xiaoshan Chen , Yan Li , Sayyed Hamad Ahmad Shah , Dong Xiao , Jianjun Wang , Xilin Hou , Tongkun Liu , Ying Li

Journal: Plant Physiol .

PubMed ID: 38269601

Doi: 10.1093/plphys/kiae021

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Lipopolysaccharides from a Shiraia fruiting body-associated bacterium elicit host fungal hypocrellin A biosynthesis through nitric oxide generation

Authors: Xin Ping Li , Wen Hao Shen , Lu Lu Zhou , Qun Yan Huang , Rui Peng Cong , Li Ping Zheng , Jian Wen Wang

Journal: Carbohydr Polym .

PubMed ID: 37985049

Doi: 10.1016/j.carbpol.2023.121498.

Products & Services: Proteins, Expression, Isolation and Analysis

Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes

Authors: Zebin Tong , Huasong Ai, Ziyu Xu , Kezhang He , Guo-Chao Chu, Qiang Shi , Zhiheng Deng, Qiaomei Xue , Maoshen Sun, Yunxiang Du , Lujun Liang, Jia-Bin Li , Man Pan , Lei Liu

Journal: Nat Struct Mol Biol .

PubMed ID: 38177667

Doi: 10.1038/s41594-023-01141-1

Products & Services: Proteins, Expression, Isolation and Analysis Gene Synthesis

Inhaled nanoparticles for treating idiopathic pulmonary fibrosis by inhibiting honeycomb cyst and alveoli interstitium remodeling

Authors: Meng-Meng Han , Ling Tang , Bin Huang , Xue-Na Li , Yue-Fei Fang , Liang Qi , Bo-Wen Duan , Ya-Ting Yao , Yu-Jing He , Lei Xing , Hu-Lin Jiang

Journal: J Control Release .

PubMed ID: 38242209

Doi: 10.1016/j.jconrel.2024.01.032

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Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation

Authors: Anlan Yang , Shengjie Liu , Yuqi Zhang , Jia Chen , Yujing Fan , Fengxiang Wang , Yilong Zou , Shan Feng , Jianping Wu , Qi Hu

Journal: Nat Struct Mol Biol .

PubMed ID: 38182928

Doi: 10.1038/s41594-023-01183-5

Products & Services: Proteins, Expression, Isolation and Analysis

Disordered-to-ordered transitions in assembly factors allow the complex II catalytic subunit to switch binding partners

Authors: Pankaj Sharma, Elena Maklashina, Markus Voehler, Sona Balintova , Sarka Dvorakova, Michal Kraus, Katerina Hadrava Vanova Zuzana Nahacka, Renata Zobalova, Stepana Boukalova, Kristyna Cunatova, Tomas Mracek, Hans K Ghayee, Karel Pacak, Jakub Rohlena, Jiri Neuzil, Gary Cecchini,T M Iverson

Journal: Nat Commun

PubMed ID: 38212624

Doi: 10.1038/s41467-023-44563-7

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MARS an improved de novo peptide candidate selection method for non-canonical antigen target discovery in cancer

Authors: Hanqing Liao , Carolina Barra , Zhicheng Zhou , Xu Peng , Isaac Woodhouse , Arun Tailor , Robert Parker , Alexia Carré , Persephone Borrow , Michael J Hogan , Wayne Paes , Laurence C Eisenlohr , Roberto Mallone , Morten Nielsen , Nicola Ternette

Journal: Nat Commun

PubMed ID: 38253617

Doi: 10.1038/s41467-023-44460-z

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The role of CD38 in inflammation-induced depression-like behavior and the antidepressant effect of (R)-ketamine

Authors: Xinying Zhang a , Teng He a , Zifeng Wu a , Yuanyuan Wang a, Hanyu Liu a, Bingyuan Zhang a, Siqi Yang a, Di Wang a, Chaoli Huang a, Jiahao Duan b, Xiangyang Xu c, Xiangqing Xu c, Kenji Hashimoto d, Riyue Jiang e, Ling Yang b, Chun Yang

Journal: Brain, behavior, and immunity

PubMed ID: 37793489

Doi: 10.1016/j.bbi.2023.09.026

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Acylspermidines are conserved mitochondrial sirtuin-dependent metabolites

Authors: Bingsen Zhang, James Mullmann, Andreas H. Ludewig, Irma R. Fernandez, Tyler R. Bales, Robert S. Weiss & Frank C. Schroeder

Journal: Nature Chemical Biology

PubMed ID: 38167917

Doi: 10.1038/s41589-023-01511-2

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Omicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue

Authors: Guoli Shi , Tiansheng Li , Kin Kui Lai , Reed F Johnson , Jonathan W Yewdell , Alex A Compton

Journal: Nat Commun

PubMed ID: 38291024

Doi: 10.1038/s41467-024-45075-8

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The role of the Toll like receptor 4 signaling in sex-specific persistency of depression-like behavior in response to chronic stress

Authors: Eun-Jeong Yang , Tal Frolinger , Umar Iqbal , Molly Estill , Li Shen , Kyle J Trageser , Giulio M Pasinetti

Journal: Brain, behavior, and immunity

PubMed ID: 37838079

Doi: 10.1016/j.bbi.2023.10.006

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Role of UPF1-LIN28A interaction during early differentiation of pluripotent stem cells

Authors: Seungwon Jung , Seung Hwan Ko , Narae Ahn , Jinsam Lee , Chang-Hwan Park , Jungwook Hwang

Journal: Nat Commun

PubMed ID: 38167913

Doi: 10.1038/s41467-023-44600-5

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CI:Mor interactions in the lysogeny switches of TP901-1 and φ13 bacteriophages

Authors: Anders K Varming, Zhiyu Huang, Ghofran M Hamad, Kim K Rasmussen, Hanne Ingmer, Mogens Kilstrup, Leila Lo Leggio

Journal: Microbiome Res Rep

PubMed ID: 38841409

Doi: 10.20517/mrr.2023.50

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IGF-I protects porcine granulosa cells from hypoxia-induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway

Authors: Zhaojun Liu, Chungang Feng, Chengyu Li, Tong He, Gang Wu, Chen Fu, Hongmin Li, Ming Shen, Honglin Liu

Journal: FASEB J

PubMed ID: 38095232

Doi: 10.1096/fj.202301464R

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Engineering of Ogataea polymorpha strains with ability for high-temperature alcoholic fermentation of cellobiose

Authors: Roksolana Vasylyshyn, Olena Dmytruk, Andriy Sybirnyy, Justyna Ruchała

Journal: FEMS Yeast Res

PubMed ID: 38400543

Doi: 10.1093/femsyr/foae007

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Assessment of the effectiveness of the peptide inhibitor homologous to the transforming growth factor β cytokine blocking the TGFβRI/TGFβRII receptor complex-pilot study

Authors: Marynowski Mateusz, Karbownik Michał Seweryn, Szemraj Janusz, Kuna Piotr, Michał Gabriel Panek

Journal: Clin Transl Allergy

PubMed ID: 38282199

Doi: 10.1002/clt2.12320

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Cell death induced by nicotine in human neuroblastoma SH-SY5Y cells is mainly attributed to cytoplasmic vacuolation originating from the trans-Golgi network

Authors: Jun Li, Hongjuan Wang, Huan Chen, Xiao Li, Yong Liu, Hongwei Hou, Qingyuan Hu

Journal: Food Chem Toxicol

PubMed ID: 38176581

Doi: 10.1016/j.fct.2023.114431

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FLUAV RAM-IGIP: A modified live influenza virus vaccine that enhances humoral and mucosal responses against influenza

Authors: C Joaquín Cáceres, L Claire Gay, Aarti Jain, Teresa D Mejías, Matias Cardenas, Brittany Seibert, Flavio Cargnin Faccin, Brianna Cowan, Ginger Geiger, Amy Vincent Baker, Silvia Carnaccini, D Huw Davies, Daniela S Rajao, Daniel R Perez

Journal: biorxiv

PubMed ID: 38328128

Doi: 10.1101/2024.01.23.576908

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FLT3L-induced virtual memory CD8 T cells engage the immune system against tumors

Authors: Hsin-Fang Tu, Yu-Jui Kung, Ling Lim, Julia Tao, Ming-Hung Hu, Michelle Cheng, Deyin Xing, T C Wu, Chien-Fu Hung

Journal: J Biomed Sci

PubMed ID: 38287325

Doi: 10.1186/s12929-024-01006-9

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Structural, Biochemical, and Bioinformatic Basis for Identifying Radical SAM Cyclopropyl Synthases

Authors: Yi Lien, Jake C Lachowicz, Aigera Mendauletova, Cynthia Zizola, Thacien Ngendahimana, Anastasiia Kostenko, Sandra S Eaton, John A Latham, Tyler L Grove

Journal: ACS Chem Biol

PubMed ID: 38295270

Doi: 10.1021/acschembio.3c00583

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Human microbiota from drug-naive patients with obsessive-compulsive disorder drives behavioral symptoms and neuroinflammation via succinic acid in mice

Authors: Ying-Dan Zhang, Dong-Dong Shi, Bing-Bing Liao, Yi Li, Sen Zhang, Jian Gao, Liang-Jun Lin, Zhen Wang

Journal: Mol Psychiatry

PubMed ID: 38273106

Doi: 10.1038/s41380-024-02424-9

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Rescue of secretion of rare-disease-associated misfolded mutant glycoproteins in UGGT1 knock-out mammalian cells

Authors: Gabor Tax, Kevin P Guay, Ludovica Pantalone, Martina Ceci, Tatiana Soldà, Charlie J Hitchman, Johan C Hill, Snežana Vasiljević, Andrea Lia, Carlos P Modenutti, Kees R Straatman, Angelo Santino, Maurizio Molinari, Nicole Zitzmann, Daniel N Hebert, Pietro Roversi, Marco Trerotola

Journal: Traffic

PubMed ID: 38272446

Doi: 10.1111/tra.12927

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GhUBC10-2 mediates GhGSTU17 degradation to regulate salt tolerance in cotton (Gossypium hirsutum)

Authors: Yaru Sun, Zailong Tian, Dongyun Zuo, Qiaolian Wang, Guoli Song

Journal: Plant Cell Environ

PubMed ID: 38282268

Doi: 10.1111/pce.14839

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Systemic effects of hypophosphatasia characterization of two novel variants in the gene

Authors: Luis Martínez-Heredia, Manuel Muñoz-Torres, Raquel Sanabria-de la Torre, Ángela Jiménez-Ortas, Francisco Andújar-Vera, Trinidad González-Cejudo, Victoria Contreras-Bolívar, Sheila González-Salvatierra, José María Gómez-Vida, Cristina García-Fontana, Beatriz García-Fontana

Journal: Front Endocrinol (Lausanne)

PubMed ID: 38234425

Doi: 10.3389/fendo.2023.1320516

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Transition Metal Ion FRET-Based Probe to Study Cu(II)-Mediated Amyloid- Ligand Binding

Authors: Ri Wu, Despoina Svingou, Jonas B Metternich, Lukas R Benzenberg, Renato Zenobi

Journal: J Am Chem Soc

PubMed ID: 38225538

Doi: 10.1021/jacs.3c11533

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Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants

Authors: Francesco Marchesani, Valeria Buoli Comani, Stefano Bruno, Andrea Mozzarelli, Mauro Carcelli, Loredano Pollegioni, Laura Caldinelli, Alessio Peracchi, Barbara Campanini

Journal: Biochim Biophys Acta Mol Basis Dis

PubMed ID: 38278334

Doi: 10.1016/j.bbadis.2024.167034

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Production of anti-human cannabinoid receptor 2 (CB2) monoclonal antibody using non-viral vector induced human CB2 expressing myeloma as an immunogen

Authors: Jindaphun Kanyaruck, Takheaw Nuchjira, Putpim Chaochetdhapada, Laopajon Witida, Kotemul Kamonporn, Chaiwut Ratthakorn, Pata Supansa, Kasinrerk Watchara

Journal: Asian Pac J Allergy Immunol

PubMed ID: 38183645

Doi: 10.12932/AP-020723-1646

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The Anti-SARS-CoV-2 IgG1 and IgG3 Antibody Isotypes with Limited Neutralizing Capacity against Omicron Elicited in a Latin Population a Switch toward IgG4 after Multiple Doses with the mRNA Pfizer-BioNTech Vaccine

Authors: Ana M Espino, Albersy Armina-Rodriguez, Laura Alvarez, Carlimar Ocasio-Malavé, Riseilly Ramos-Nieves, Esteban I Rodriguez Martinó, Paola López-Marte, Esther A Torres, Carlos A Sariol

Journal: Viruses

PubMed ID: 38399963

Doi: 10.3390/v16020187

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BBS genes are involved in accelerated proliferation and early differentiation of BBS-related tissues

Authors: Avital Horwitz, Noa Levi-Carmel, Olga Shnaider, Ruth Birk

Journal: Differentiation

PubMed ID: 38215537

Doi: 10.1016/j.diff.2024.100745

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Cytoophidia Influence Cell Cycle and Size in

Authors: Ruolan Deng, Yi-Lan Li, Ji-Long Liu

Journal: Int J Mol Sci

PubMed ID: 38203781

Doi: 10.3390/ijms25010608

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Endolysin NC5 improves early cloxacillin treatment in a mouse model of Streptococcus uberis mastitis

Authors: Niels Vander Elst, Julie Bellemans, Rob Lavigne, Yves Briers, Evelyne Meyer

Journal: Appl Microbiol Biotechnol

PubMed ID: 38204128

Doi: 10.1007/s00253-023-12820-w

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Irreversible light-activated SpyLigation mediates split-protein assembly in 4D

Authors: Brizzia G Munoz-Robles, Cole A DeForest

Journal: Nat Protoc

PubMed ID: 38253657

Doi: 10.1038/s41596-023-00938-0

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Blocking the E2F transcription factor 1/high-mobility group box 2 pathway enhances the intervention effects of α-santalol on the malignant behaviors of liver cancer cells

Authors: Hui Wang, Min Tang, Erli Pei, Ying Shen, Aili Wang, Moubin Lin

Journal: Int J Biochem Cell Biol

PubMed ID: 38219975

Doi: 10.1016/j.biocel.2024.106516

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N-acetyltransferase 10 regulates alphavirus replication via N4- acetylcytidine (ac4C) modification of the lymphocyte antigen six family member E (LY6E) mRNA

Authors: Yamei Dang , Jia Li , Yuchang Li , Yuan Wang , Yajing Zhao , Ningbo Zhao , Wanying Li , Hui Zhang , Chuantao Ye , Hongwei Ma , Liang Zhang , He Liu , Yangchao Dong , Min Yao , Yingfeng Lei , Zhikai Xu , Fanglin Zhang , Wei Ye

Journal: J Virol .

PubMed ID: 38169284

Doi: 10.1128/jvi.01350-23

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Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

Authors: Gisele Nishiguchi , Lauren G Mascibroda , Sarah M Young , Elizabeth A Caine , Sherif Abdelhamed , Jeffrey J Kooijman , Darcie J Miller , Sourav Das , Kevin McGowan , Anand Mayasundari , Zhe Shi , Juan M Barajas , Ryan Hiltenbrand , Anup Aggarwal , Yunchao Chang , Vibhor Mishra , Shilpa Narina , Melvin Thomas , Allister J Loughran , Ravi Kalathur , Kaiwen Yu , Suiping Zhou , Xusheng Wang , Anthony A High , Junmin Peng , Shondra M Pruett-Miller , Danette L Daniels , Marjeta Urh , Anang A Shelat , Charles G Mullighan , Kristin M Riching , Guido J R Zaman , Marcus Fischer , Jeffery M Klco , Zoran Rankovic

Journal: Nat Commun

PubMed ID: 38228616

Doi: 10.1038/s41467-024-44698-1

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Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

Authors: Ayijiang Yisimayi, Weiliang Song, Jing Wang, Fanchong Jian, Yuanling Yu, Xiaosu Chen, Yanli Xu, Sijie Yang, Xiao Niu, Tianhe Xiao, Jing Wang , Lijuan Zhao, Haiyan Sun, Ran An, Na Zhang, Yao Wang, Peng Wang, Lingling Yu, Zhe Lv, Qingqing Gu, Fei Shao, Ronghua Jin, Zhongyang Shen, Xiaoliang Sunney Xie, Youchun Wang, Yunlong Cao

Journal: Nature

PubMed ID: 37993710

Doi: 10.1038/s41586-023-06753-7

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Structural basis of Gabija anti-phage defence and viral immune evasion

Authors: Sadie P Antine, Alex G Johnson, Sarah E Mooney, Azita Leavitt, Megan L Mayer, Erez Yirmiya, Gil Amitai, Rotem Sorek, Philip J Kranzusch

Journal: Nature

PubMed ID: 37992757

Doi: 10.1038/s41586-023-06855-2

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A synthetic differentiation circuit in Escherichia coli for suppressing mutant takeover

Authors: David S Glass 1, Anat Bren 2, Elizabeth Vaisbourd 2, Avi Mayo 2, Uri Alon

Journal: Cell

PubMed ID: 38320549

Doi: 10.1016/j.cell.2024.01.024

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Sirtuin 3 is required for the dexmedetomidine-mediated alleviation of inflammation and oxidative stress in nephritis

Authors: Kai Lu , Xinlong Li , Jie Wu

Journal: Immunity

PubMed ID: 38270316

Doi: 10.1002/iid3.1135

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Molecular Atlas of HER2+ Breast Cancer Cells Treated with Endogenous Ligands: Temporal Insights into Mechanisms of Trastuzumab Resistance

Authors: Kavitha Mukund, Jackelyn A Alva-Ornelas, Adam L Maddox, Divya Murali, Darya Veraksa, Andras Saftics, Jerneja Tomsic, David Frankhouser, Meagan Razo, Tijana Jovanovic-Talisman, Victoria L Seewaldt, Shankar Subramaniam

Journal: Cancers (Basel)

PubMed ID: 38339304

Doi: 10.3390/cancers16030553

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Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44

Authors: Emily M Cross, Oriano Marin, Daryl Ariawan, David Aragão, Giorgio Cozza, Enzo Di Iorio, Jade K Forwood, Gualtiero Alvisi

Journal: FEBS Lett

PubMed ID: 38158756

Doi: 10.1002/1873-3468.14797

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Myosin Va-dependent Transport of NMDA Receptors in Hippocampal Neurons

Authors: Ru Gong, Linwei Qin, Linlin Chen, Ning Wang, Yifei Bao, Wei Lu

Journal: Neurosci Bull

PubMed ID: 38291290

Doi: 10.1007/s12264-023-01174-y

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Revamped mini-αA-crystallin showed improved skin permeation and therapeutic activity against melittin-induced toxicity

Authors: Tenzin Tender, Rakesh Ravishankar Rahangdale, Madhavan Nampoothiri, Ruchira Raychaudhuri, Srinivas Mutalik, Krishna Sharma, Raghu Chandrashekar H

Journal: Toxicon

PubMed ID: 38211805

Doi: 10.1016/j.toxicon.2024.107611

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Variable PD-1 glycosylation modulates the activity of immune checkpoint inhibitors

Authors: Chih-Wei Chu, Tomislav Čaval, Frederico Alisson-Silva, Akshaya Tankasala, Christina Guerrier, Gregg Czerwieniec, Heinz Läubli, Flavio Schwarz

Journal: Life Sci Alliance

PubMed ID: 38176728

Doi: 10.26508/lsa.202302368

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