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S100A12 protein as a porcine health status biomarker when quantified in saliva samples

Authors: A M Gutiérrez, M Matas-Quintanilla, M Piñeiro, J Sánchez, P Fuentes, F J Ibáñez-López

Journal: Vet J

PubMed ID: 38215874

Doi: 10.1016/j.tvjl.2024.106062

Products & Services: Proteins, Expression, Isolation and Analysis

A high catalytic efficiency and chemotolerant formate dehydrogenase from Bacillus simplex

Authors: Rattima Boonkumkrong, Paweenapon Chunthaboon, Pobthum Munkajohnpong, Pratchaya Watthaisong, Panu Pimviriyakul, Somchart Maenpuen, Pimchai Chaiyen, Ruchanok Tinikul

Journal: Biotechnol J

PubMed ID: 38180313

Doi: 10.1002/biot.202300330

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Sast1-mediated manifold effects inhibit Plutella xylostella fertility

Authors: Min-Hui Cao, Ming-Min Zou, Li-Li Liu, Shi-Jie Dong, Meng-Qi Huang, Jun-Hao Zheng, Ruo-Nan Li, Jin-Dong Cui, Lu Peng

Journal: Pest Manag Sci

PubMed ID: 38252701

Doi: 10.1002/ps.7966

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Self-cascade deoxynivalenol detoxification by an artificial enzyme with bifunctions of dehydrogenase and aldo/keto reductase from genome mining

Authors: Jiafeng Niu, Ruxue Yan, Huimin Zhou, Bin Ma, Zhaoxin Lu, Fanqiang Meng, Fengxia Lu, Ping Zhu

Journal: Int J Biol Macromol

PubMed ID: 38246466

Doi: 10.1016/j.ijbiomac.2024.129512

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VEGF-delivering PEG hydrogels promote vascularization in the porcine subcutaneous space

Authors: Michelle J Quizon, Juline N Deppen, Graham F Barber, Pranav P Kalelkar, María M Coronel, Rebecca D Levit, Andres J Garcia

Journal: J Biomed Mater Res A

PubMed ID: 38189109

Doi: 10.1002/jbm.a.37666

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Nitrated T cell epitope linked vaccine targeting CD47 elicits antitumor immune responses and acts synergistically with vaccine targeting PDL1

Authors: Danni Deng, Guozhi Li, Xuefei Xia, Shuyang Xu, Le Gao, Li Zhang, Wenbing Yao, Hong Tian, Xiangdong Gao

Journal: Int Immunopharmacol

PubMed ID: 38181672

Doi: 10.1016/j.intimp.2023.111374

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FS145, the first flea-derived disintegrin, inhibits angiogenesis through specifically binding integrin αβ

Authors: Wancheng Lu, Zhijian Xiao, Hang Liao, Jianpeng Xie, Yihan Gao, Weichen Xiong, Qingye Zeng, Zhenhui Deng, Jiena Wu, Jinwei Chai, Xin Chen, Xueqing Xu

Journal: Int J Biol Macromol

PubMed ID: 38211910

Doi: 10.1016/j.ijbiomac.2024.129289

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Development of nanobodies specific to clumping factors A of Staphylococcus aureus by yeast surface display

Authors: Meng Mei, Mengqing Lu, Shiqi Li, Xinyi Ren, Banbin Xing, Yang Hu, Yuqi Wu, Huan Chen, Longhao Wang, Li Yi, Ke Ming, Zigong Wei

Journal: Int J Biol Macromol

PubMed ID: 38185298

Doi: 10.1016/j.ijbiomac.2024.129208

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Immunogenicity studies of recombinant RBD SARS-CoV-2 as a COVID-19 vaccine candidate produced in

Authors: Intan Aghniya Safitri, Yovin Sugijo, Fernita Puspasari, Fifi Fitriyah Masduki, Ernawati Arifin Giri-Rachman, Aluicia Anita Artarini, Marselina Irasonia Tan, Dessy Natalia

Journal: Vaccine X

PubMed ID: 38304876

Doi: 10.1016/j.jvacx.2024.100443

Products & Services: Molecular Biology Reagents

Genetic engineering employing MPB70 and its promoter enables efficient secretion and expression of foreign antigen in bacillus Calmette Guérin (BCG) Tokyo

Authors: Atsuki Takeishi, Amina K Shaban, Taichi Kakihana, Hayato Takihara, Shujiro Okuda, Hidekazu Osada, Desak Nyoman Surya Suameitria Dewi, Yuriko Ozeki, Yutaka Yoshida, Akihito Nishiyama, Yoshitaka Tateishi, Yuki Aizu, Yasushi Chuma, Kazuyo Onishi, Daisuke Hayashi, Saburo Yamamoto, Tetsu Mukai, Manabu Ato, Duong Huu Thai, Huynh Thi Thao Nhi, Tsuyoshi Shirai, Satoshi Shibata, Fumiko Obata, Jun Fujii, Seiya Yamayoshi, Maki Kiso, Sohkichi Matsumoto

Journal: Microbiol Immunol

PubMed ID: 38294180

Doi: 10.1111/1348-0421.13116

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Studying the topology of peroxisomal acyl-CoA synthetases using self-assembling split sfGFP

Authors: Serhii Chornyi, Janet Koster, Lodewijk IJlst, Hans R Waterham

Journal: Histochem Cell Biol

PubMed ID: 38243092

Doi: 10.1007/s00418-023-02257-7

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Performance Analysis of Serodiagnostic Tests to Characterize the Incline and Decline of the Individual Humoral Immune Response in COVID-19 Patients: Impact on Diagnostic Management

Authors: Ronald von Possel, Babett Menge, Christina Deschermeier, Carlos Fritzsche, Christoph Hemmer, Hilte Geerdes-Fenge, Micha Loebermann, Anette Schulz, Erik Lattwein, Katja Steinhagen, Ralf Tönnies, Reiner Ahrendt, Petra Emmerich

Journal: Viruses

PubMed ID: 38257792

Doi: 10.3390/v16010091

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Generation and Application of Monoclonal Antibodies against Porcine S100A8, S100A9, and S100A12 Proteins Using Hybridoma Technology

Authors: Pengpeng Xia, Xin Ma, Li Yan, Siqi Lian, Xiangyu Li, Yi Luo, Ziyue Chen, Xingduo Ji

Journal: Int J Mol Sci

PubMed ID: 38256103

Doi: 10.3390/ijms25021029

Products & Services: Proteins, Expression, Isolation and Analysis

A Non-Functional Carbon Dioxide-Mediated Post-Translational Modification on Nucleoside Diphosphate Kinase of

Authors: Harry G Gannon, Amber Riaz-Bradley, Martin J Cann

Journal: Int J Mol Sci

PubMed ID: 38255974

Doi: 10.3390/ijms25020898

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Role of Histiocyte-Derived frHMGB1 as a Facilitator in Non-Canonical Pyroptosis of Monocytes/Macrophages in Lethal Sepsis

Authors: Yu Tian, Yuwen Cao, Fang Liu, Lin Xia, Chao Wang, Zhaoliang Su

Journal: J Infect Dis

PubMed ID: 38243905

Doi: 10.1093/infdis/jiae020

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Chimeric proteins of Mycoplasma hyopneumoniae as vaccine and preclinical model for immunological evaluation

Authors: Marcus Rebouças Santos, Leonardo Teófilo Toledo, Ênio José Bassi, Wagnner José Nascimento Porto, Gustavo Costa Bressan, Maria Aparecida S Moreira, Yung-Fu Chang, Abelardo Silva-Júnior

Journal: Braz J Microbiol

PubMed ID: 38217795

Doi: 10.1007/s42770-023-01240-7

Products & Services: Proteins, Expression, Isolation and Analysis

Electrically silent KvS subunits associate with native Kv2 channels in brain and impact diverse properties of channel function

Authors: Michael Ferns, Deborah van der List, Nicholas C Vierra, Taylor Lacey, Karl Murray, Michael Kirmiz, Robert G Stewart, Jon T Sack, James S Trimmer

Journal: biorxiv

PubMed ID: 38328147

Doi: 10.1101/2024.01.25.577135

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Recombinant T7 RNA polymerase production using ClearColi BL21(DE3) and animal-free media for in vitro transcription

Authors: Qianying Liang, Bowen Tu, Lun Cui

Journal: Appl Microbiol Biotechnol

PubMed ID: 38180552

Doi: 10.1007/s00253-023-12939-w

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Astragaloside IV regulates circ_0001615 and miR-873-5p/LASP1 axis to suppress colorectal cancer cell progression

Authors: Pengfei Kong, Xuemei Tang, Fang Liu, Xuegui Tang

Journal: Chem Biol Drug Des

PubMed ID: 38230773

Doi: 10.1111/cbdd.14423

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Prevalence of IgG antibodies against Malawi polyomavirus in patients with autoimmune diseases and lymphoproliferative disorders subjected to bone marrow transplantation

Authors: Jérôme T J Nicol, Elisa Mazzoni, Maria Rosa Iaquinta, Raffaella De Pace, Pauline Gaboriaud, Natalia Maximova, Carolina Cason, Eleonora De Martino, Chiara Mazziotta, Pierre Coursaget, Antoine Touzé, Valentina Boz, Manola Comar, Mauro Tognon, Fernanda Martini

Journal: Front Immunol

PubMed ID: 38299147

Doi: 10.3389/fimmu.2023.1293313

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Evolutionary preservation of CpG dinucleotides in RAG1 may elucidate the relatively high rate of methylation-mediated mutagenesis of RAG1 transposase

Authors: Mariam M Fawzy, Maiiada H Nazmy, Azza A K El-Sheikh, Moustafa Fathy

Journal: Immunol Res

PubMed ID: 38240953

Doi: 10.1007/s12026-023-09451-8

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Glycosylase-based base editors for efficient T-to-G and C-to-G editing in mammalian cells

Authors: Lijun Ye , Dongdong Zhao , Ju Li , Yiran Wang , Bo Li , Yuanzhao Yang , Xueting Hou , Huibin Wang , Zhandong Wei , Xiaoqi Liu , Yaqiu Li, Siwei Li , Yajing Liu , Xueli Zhang , Changhao Bi

Journal: Nat Biotechnol .

PubMed ID: 38168994

Doi: 10.1038/s41587-023-02050-w

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Cross-feeding promotes heterogeneity within yeast cell populations

Authors: Kevin K Y Hu, Ankita Suri, Geoff Dumsday, Victoria S Haritos

Journal: Nat Commun

PubMed ID: 38200012

Doi: 10.1038/s41467-023-44623-y

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Cyclic di-GMP inhibits nitrate assimilation by impairing the antitermination function of NasT in Pseudomonas putida

Authors: Liang Nie, Yujie Xiao, Tiantian Zhou, Haoqi Feng, Meina He, Qingyuan Liang, Kexin Mu, Hailing Nie, Qiaoyun Huang, Wenli Chen

Journal: Nucleic Acids Res

PubMed ID: 38000372

Doi: 10.1093/nar/gkad1117

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Impact of surface receptors TLR2, CR3, and FcγRIII on Rhodococcus equi phagocytosis and intracellular survival in macrophages

Authors: Bibiana Petri da Silveira , Rola Barhoumi , Jocelyne M Bray , Hannah M Cole-Pfeiffer , Cory J Mabry , Robert C Burghardt , Noah D Cohen, Angela I Bordin

Journal: Immunity

PubMed ID: 38018994

Doi: 10.1128/iai.00383-23

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The HIV capsid mimics karyopherin engagement of FG-nucleoporins

Authors: C. F. Dickson, S. Hertel, A. J. Tuckwell, N. Li, J. Ruan, S. C. Al-Izzi, N. Ariotti, E. Sierecki, Y. Gambin, R. G. Morris, G. J. Towers, T. Böcking & D. A. Jacques

Journal: Nature

PubMed ID: 38267582

Doi: 10.1038/s41586-023-06969-7

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The cryo-EM structure of homotetrameric attachment glycoprotein from langya henipavirus

Authors: Yingying Guo , Songyue Wu , Wenting Li , Haonan Yang , Tianhao Shi , Bin Ju , Zheng Zhang , Renhong Yan

Journal: Nat Commun

PubMed ID: 38280880

Doi: 10.1038/s41467-024-45202-5

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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

Authors: Eike-Christian Wamhoff , Larance Ronsard , Jared Feldman , Grant A Knappe , Blake M Hauser , Anna Romanov , James Brett Case , Shilpa Sanapala , Evan C Lam , Kerri J St Denis , Julie Boucau , Amy K Barczak , Alejandro B Balazs , Michael S Diamond , Aaron G Schmidt , Daniel Lingwood , Mark Bathe

Journal: Nat Commun

PubMed ID: 38291019

Doi: 10.1038/s41467-024-44869-0

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Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy

Authors: Binh An Nguyen , Virender Singh , Shumaila Afrin , Anna Yakubovska , Lanie Wang , Yasmin Ahmed , Rose Pedretti , Maria Del Carmen Fernandez-Ramirez , Preeti Singh , Maja Pękała , Luis O Cabrera Hernandez , Siddharth Kumar , Andrew Lemoff , Roman Gonzalez-Prieto , Michael R Sawaya , David S Eisenberg , Merrill Douglas Benson , Lorena Saelices

Journal: Nat Commun

PubMed ID: 38233397

Doi: 10.1038/s41467-024-44820-3

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STYXL1 regulates CCT complex assembly and flagellar tubulin folding in sperm formation

Authors: Yu Chen , Mengjiao Luo , Haixia Tu , Yaling Qi , Yueshuai Guo , Xiangzheng Zhang , Yiqiang Cui , Mengmeng Gao , Xin Zhou , Tianyu Zhu , Hui Zhu , Chenghao Situ , Yan Li , Xuejiang Guo

Journal: Nat Commun

PubMed ID: 38168070

Doi: 10.1038/s41467-023-44337-1

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Cryo-EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH

Authors: Niraj Kumar , Shivani Sharma , Prem S Kaushal

Journal: Nat Commun

PubMed ID: 38245551

Doi: 10.1038/s41467-024-44879-y

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Biomimetic Control over Bimetallic Nanoparticle Structure and Activity via Peptide Capping Ligand Sequence

Authors: Maichong Xie, Ryuichi Shimogawa, Yang Liu, Lihua Zhang, Alexandre C. Foucher, Prahlad K. Routh, Eric A. Stach, Anatoly I. Frenkel*, and Marc R. Knecht

Journal: ACS Nano

PubMed ID: 38227802

Doi: 10.1021/acsnano.3c10016

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Single-Molecule Analysis of SARS-CoV-2 Double-Stranded Polynucleotides Using Solid-State Nanopore with AI-Assisted Detection and Classification: Implications for Understanding Disease Severity

Authors: Ibrar Alam, Thitikorn Boonkoom, Harit Pitakjakpipop, Poramin Boonbanjong, Kawin Loha, Thanaya Saeyang, Jarunee Vanichtanankul, Deanpen Japrung

Journal: ACS Appl Bio Mater

PubMed ID: 38194666

Doi: 10.1021/acsabm.3c00998

Products & Services: PCR Cloning and Subcloning

A general platform for targeting MHC-II antigens via a single loop

Authors: Haotian Du, Jingjia Liu, Kevin M Jude, Xinbo Yang, Ying Li, Braxton Bell, Hongli Yang, Audrey Kassardjian, Ali Mobedi, Udit Parekh, R Andres Parra Sperberg, Jean-Philippe Julien, Elizabeth D Mellins, K Christopher Garcia, Po-Ssu Huang

Journal: biorxiv

PubMed ID: 38352315

Doi: 10.1101/2024.01.26.577489

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PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease

Authors: Guangyu Zhou, Chen Zhang, Hui Peng, Xuesong Su, Qun Huang, Zixia Zhao, Guangyi Zhao

Journal: Mol Med

PubMed ID: 38200452

Doi: 10.1186/s10020-023-00759-7

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Structural insights into the activation and inhibition of CXC chemokine receptor 3

Authors: Haizhan Jiao, Bin Pang, Aijun Liu, Qiang Chen, Qi Pan, Xiankun Wang, Yunong Xu, Ying-Chih Chiang, Ruobing Ren, Hongli Hu

Journal: Nat Struct Mol Biol

PubMed ID: 38177682

Doi: 10.1038/s41594-023-01175-5

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Structural biases in disordered proteins are prevalent in the cell

Authors: David Moses, Karina Guadalupe, Feng Yu, Eduardo Flores, Anthony R Perez, Ralph McAnelly, Nora M Shamoon, Gagandeep Kaur, Estefania Cuevas-Zepeda, Andrea D Merg, Erik W Martin, Alex S Holehouse, Shahar Sukenik

Journal: Nat Struct Mol Biol

PubMed ID: 38177684

Doi: 10.1038/s41594-023-01148-8

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Response to COVID-19 vaccination in patients on cancer therapy: Analysis in a SARS-CoV-2-naïve population

Authors: George Cavic, Andrew A Almonte, Sarah M Hicks, Teresa Neeman, Jo-Wai Wang, Sue Brew, Philip Y Choi, Ian Cockburn, Elizabeth E Gardiner, Desmond Yip, Aude M Fahrer, Yada Kanjanapan

Journal: Asia Pac J Clin Oncol

PubMed ID: 38221764

Doi: 10.1111/ajco.14047

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PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial

Authors: Francisco J Martinez, Michael White, Micheline Guillotte-Blisnick, Christèle Huon, Alix Boucharlat, Fabrice Agou, Patrick England, Jean Popovici, Mimi M Hou, Sarah E Silk, Jordan R Barrett, Carolyn M Nielsen, Jenny M Reimer, Paushali Mukherjee, Virander S Chauhan, Angela M Minassian, Simon J Draper, Chetan E Chitnis

Journal: npj Vaccines

PubMed ID: 38184681

Doi: 10.1038/s41541-023-00796-7

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Comparative Study on the Immunogenicity of COVID-19 mRNA Vaccines in Patients Receiving Adjuvant and Palliative Chemotherapy

Authors: Hyun-Woo Choi, Younggon Jung, Uh Jin Kim, Sang-Cheol Lee, Jung Hye Kwon, Hyeonjong Kim, Sarah Kim, Yoonjung Lee, Hyun-Jung Shim, Sang-Hee Cho, Ik-Joo Chung, Eu Chang Hwang, Seung Ji Kang, Woo Kyun Bae, Seung-Jung Kee

Journal: Chonnam Med J

PubMed ID: 38304127

Doi: 10.4068/cmj.2024.60.1.69

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Up-regulation of lncRNA WT1-AS ameliorates Aβ-stimulated neuronal injury through modulation of miR-186-5p/CCND2 axis in Alzheimer's disease

Authors: Yun Tang, Xiaojiu Zhang, Shihui Wang, Lu Liu, Qing Wang, Yufeng Liu, Yadong Yu, Qijin Zhai

Journal: Cell Mol Biol (Noisy-le-grand)

PubMed ID: 38372094

Doi: 10.14715/cmb/2024.70.1.27

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Spatial and Single-Cell Transcriptomics Reveal a Cancer-Associated Fibroblast Subset in HNSCC That Restricts Infiltration and Antitumor Activity of CD8+ T Cells

Authors: Chuwen Li, Haiyan Guo, Peisong Zhai, Ming Yan, Chun Liu, Xiaoning Wang, Chaoji Shi, Jiang Li, Tong Tong, Zhiyuan Zhang, Hailong Ma, Jianjun Zhang

Journal: Cancer Res

PubMed ID: 37930937

Doi: 10.1158/0008-5472.CAN-23-1448

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Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake

Authors: Kazuki Takeda, Taki Saito, Sakura Sasaki, Akifumi Eguchi, Makoto Sugiyama, Saeka Eto, Kio Suzuki, Ryo Kamata

Journal: Toxics

PubMed ID: 38251008

Doi: 10.3390/toxics12010052

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Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia

Authors: Wenhua Jiang, Qiangqiang Hou, Hongrui Xu, Kexin Yang, Xiaohui Wang, Kuojun Zhang, Yi Zeng, Wenqiang Li, Bingrui Wang, Guangmei Luo, Xiaofan Zhao, Hui Shen, Yong Xu, Xiaoxing Wu

Journal: J Med Chem

PubMed ID: 38175809

Doi: 10.1021/acs.jmedchem.3c02104

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Local Multiple-site Injections of a Plasmid Encoding Human Mitigate Radiation-induced Skin Injury by Inhibiting Ferroptosis

Authors: Xiaoying Wang, Yuxin Lu, Xiaochen Cheng, Xuefeng Zhu, Dujuan Li, Haiying Duan, Shenhui Hu, Fengjun Xiao, Li Du, Qinglin Zhang

Journal: Curr Drug Deliv

PubMed ID: 37157191

Doi: 10.2174/1567201820666230508120720

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Bioactive Polyurethane-Poly(ethylene Glycol) Diacrylate Hydrogels for Applications in Tissue Engineering

Authors: Yixuan Yuan, Caleb Tyson, Annika Szyniec, Samuel Agro, Tara N Tavakol, Alexander Harmon, DessaRae Lampkins, Lauran Pearson, Jerald E Dumas, Lakeshia J Taite

Journal: Gels

PubMed ID: 38391438

Doi: 10.3390/gels10020108

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Enhanced immunogenicity and protective efficacy in mice following a Zika DNA vaccine designed by modulation of membrane-anchoring regions and its association to adjuvants

Authors: Franciane Mouradian Emidio Teixeira, Luana de Mendonça Oliveira, Anna Cláudia Calvielli Castelo Branco, Ricardo Wesley Alberca, Emanuella Sarmento Alho de Sousa, Bruno Henrique de Sousa Leite, Wenny Camilla Dos Santos Adan, Alberto José da Silva Duarte, Roberto Dias Lins, Maria Notomi Sato, Isabelle Freire Tabosa Viana

Journal: Front Immunol

PubMed ID: 38361945

Doi: 10.3389/fimmu.2024.1307546

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Inter-alpha-trypsin inhibitor (IαI) and hyaluronan modifications enhance the innate immune response to influenza virus in the lung

Authors: Fengying Tang, Stephen R Reeves, Jourdan E Brune, Mary Y Chang, Christina K Chan, Peter Waldron, Sheona P Drummond, Caroline M Milner, Kimberly M Alonge, Stavros Garantziotis, Anthony J Day, William A Altemeier, Charles W Frevert

Journal: Matrix Biol

PubMed ID: 38232913

Doi: 10.1016/j.matbio.2024.01.004

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In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy

Authors: Brandon Lam, Yu Jui Kung, John Lin, Ssu-Hsueh Tseng, Hsin-Fang Tu, Claire Huang, Brandon Lee, Esteban Velarde, Ya Chea Tsai, Rafael Villasmil, Sung Taek Park, Deyin Xing, Chien-Fu Hung, T-C Wu

Journal: J Clin Invest

PubMed ID: 37917174

Doi: 10.1172/JCI171621

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The naringenin-dependent regulator FdeR can be applied as a NIMPLY gate controlled by naringenin and arabinose

Authors: Fernanda Miyuki Kashiwagi, Brenno Wendler Miranda, Emanuel Maltempi de Souza, Marcelo Müller-Santos

Journal: Synth Biol (Oxf)

PubMed ID: 38249314

Doi: 10.1093/synbio/ysae001

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A Novel Role for the Adenovirus L4 Region 22K and 33K Proteins in Adeno-Associated Virus Production

Authors: Angela Adsero, Brendan Chestnut, Sara Shahnejat-Bushehri, Lalita Sasnoor, Travis McMurphy, Mike Swenor, Ryan Pasquino, Arun Pradhan, Victor Hernandez, Linas Padegimas, David Dismuke

Journal: Hum Gene Ther

PubMed ID: 38062776

Doi: 10.1089/hum.2023.146

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Cascaded amplifying circuit enables sensitive detection of fungal pathogens

Authors: Cong Fan, Nike He, Jifeng Yuan

Journal: Biosens Bioelectron

PubMed ID: 38281368

Doi: 10.1016/j.bios.2024.116058

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An inducible CRISPRi circuit for tunable dynamic regulation of gene expression in Saccharopolyspora erythraea

Authors: Xing Jiang, Xiang Ke, Xiwei Tian, Ju Chu

Journal: Biotechnol Lett

PubMed ID: 38279045

Doi: 10.1007/s10529-023-03462-z

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Estimation of the Parasitic Burden of Soil-Transmitted Helminths Among Pregnant Women in the Maharashtra State of India Using qPCR: A Community-Based Study

Authors: Shilpa Gaidhane, Abhay Gaidhane, Mahalaqua Nazli Khatib, Shital Telrandhe, Manoj Patil, Deepak Saxena, Pankaj Bhardwaj, Sonali Choudhari, Quazi S Zahiruddin

Journal: Indian J Community Med

PubMed ID: 38425985

Doi: 10.4103/ijcm.ijcm_249_23

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KDM6A Demethylase Regulates Renal Sodium Excretion and Blood Pressure

Authors: Xiaobin Han, Leah Akinseye, Zhongjie Sun

Journal: Hypertension

PubMed ID: 38164755

Doi: 10.1161/HYPERTENSIONAHA.123.22026

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Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from

Authors: Fredrik Leo, Rolf Lood, Kristina A Thomsson, Jonas Nilsson, Gunnel Svensäter, Claes Wickström

Journal: Front Microbiol

PubMed ID: 38304711

Doi: 10.3389/fmicb.2024.1340109

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Functionally coherent transcriptional responses of Jatropha curcas and Pseudomonas fragi for rhizosphere mediated degradation of pyrene

Authors: L Paikhomba Singha, K Malabika Singha, Piyush Pandey

Journal: Sci Rep

PubMed ID: 38200308

Doi: 10.1038/s41598-024-51581-y

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A Mixture of T-Cell Epitope Peptides Derived from Human Respiratory Syncytial Virus F Protein Conferred Protection in DR1-TCR Tg Mice

Authors: Hong Guo, Yang Song, Hai Li, Hongqiao Hu, Yuqing Shi, Jie Jiang, Jinyuan Guo, Lei Cao, Naiying Mao, Yan Zhang

Journal: Vaccines (Basel)

PubMed ID: 38250890

Doi: 10.3390/vaccines12010077

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Safety, Immunogenicity, and Mechanism of a Rotavirus mRNA-LNP Vaccine in Mice

Authors: Chenxing Lu, Yan Li, Rong Chen, Xiaoqing Hu, Qingmei Leng, Xiaopeng Song, Xiaochen Lin, Jun Ye, Jinlan Wang, Jinmei Li, Lida Yao, Xianqiong Tang, Xiangjun Kuang, Guangming Zhang, Maosheng Sun, Yan Zhou, Hongjun Li

Journal: Viruses

PubMed ID: 38399987

Doi: 10.3390/v16020211

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Efficient treatment of colon cancer with codelivery of TRAIL and imatinib by liposomes

Authors: Rongrong Fu, Rui Chang, Andong Peng, Changshun Feng, Weifan Zhu, Yi Chen, Xue Tian, Rui Wang, Hui Yan, Dianlong Jia, Jun Li

Journal: Pharm Dev Technol

PubMed ID: 38230653

Doi: 10.1080/10837450.2024.2301763

Products & Services: Proteins, Expression, Isolation and Analysis

Host protein EPCAM interacting with EtMIC8-EGF is essential for attachment and invasion of Eimeria tenella in chickens

Authors: Lingyu Sun, Chao Li, Ningning Zhao, Bingxiang Wang, Hongmei Li, Hairong Wang, Xiao Zhang, Xiaomin Zhao

Journal: Microb Pathog

PubMed ID: 38281605

Doi: 10.1016/j.micpath.2024.106549

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HCMV IE1/IE1mut Therapeutic Vaccine Induces Tumor Regression via Intratumoral Tertiary Lymphoid Structure Formation and Peripheral Immunity Activation in Glioblastoma Multiforme

Authors: Xiaoli Yang, Shasha Jiang, Fengjun Liu, Zonghui Li, Wenxuan Liu, Xianjuan Zhang, Fulong Nan, Jun Li, Meng Yu, Yunyang Wang, Bin Wang

Journal: Mol Neurobiol

PubMed ID: 38261253

Doi: 10.1007/s12035-024-03937-8

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Engineering for Sustainable Production of the Pomegranate Seed Oil-Derived Punicic Acid

Authors: Kaifeng Wang, Yueyue Zhou, Lizhen Cao, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji

Journal: J Agric Food Chem

PubMed ID: 38282297

Doi: 10.1021/acs.jafc.3c08718

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Mitochondrial Homeostasis Regulating Mitochondrial Number and Morphology Is a Distinguishing Feature of Skeletal Muscle Fiber Types in Marine Teleosts

Authors: Busu Li, Huan Wang, Xianghui Zeng, Shufang Liu, Zhimeng Zhuang

Journal: Int J Mol Sci

PubMed ID: 38338790

Doi: 10.3390/ijms25031512

Products & Services: Proteins, Expression, Isolation and Analysis

Capsid protein mediated evasion of IRAK1-dependent signalling is essential to Sindbis virus neuroinvasion and virulence in mice

Authors: V Douglas Landers, Milton Thomas, Cierra M Isom, Deepa Karki, Kevin J Sokoloski

Journal: Emerg Microbes Infect

PubMed ID: 38164715

Doi: 10.1080/22221751.2023.2300452

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Chronic cortisol stimulation enhances hypothalamus-specific enrichment of metabolites in the rainbow trout brain

Authors: Ayelén M Blanco, Femilarani Antomagesh, Sara Comesaña, José L Soengas, Mathilakath M Vijayan

Journal: Am J Physiol Endocrinol Metab

PubMed ID: 38294699

Doi: 10.1152/ajpendo.00410.2023

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Assessing the protection elicited by virus-like particles expressing the RSV pre-fusion F and tandem repeated G proteins against RSV rA2 line19F infection in mice

Authors: Min-Ju Kim, Ki Back Chu, Su-Hwa Lee, Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Eun-Kyung Moon, Fu-Shi Quan

Journal: Respir Res

PubMed ID: 38178222

Doi: 10.1186/s12931-023-02641-w

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A metalloprotein nanoparticle scaffold co-delivers antigens and adjuvants with metal-enhanced STING activation for vaccination preventing viral infections

Authors: Jiexin Li , Qian Qiu , He Ren , Jingyu Zhang , Chen Zhang , Gengqi Liu , Boyang Sun , Bin Zheng , Jonathan F. Lovell , Yumiao Zhang

Journal: Nano Today

Doi: 10.1016/j.nantod.2024.102156

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Rapid production of chimeric silkworm/spider silk with improved mechanical properties by infection of nonpermissive Bombyx mori with recombinant AcMNPV harboring native-size of spidroin genes

Authors: Xiaolong Hu, Nan Li , Sicheng Guo, Min Zhu , Xing Zhang , Chonglong Wang , Chengliang Gong

Journal: Int J Biol Macromol .

PubMed ID: 38035957

Doi: 10.1016/j.ijbiomac.2023.128466.

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CGI1746 targets σ1R to modulate ferroptosis through mitochondria-associated membranes

Authors: Zili Zhang, Hong Zhou, Wenjia Gu, Yuehan Wei, Shan Mou, Youjun Wang, Jing Zhang & Qing Zhong

Journal: Nature Chemical Biology

PubMed ID: 38212578

Doi: 10.1038/s41589-023-01512-1

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A novel starch-active lytic polysaccharide monooxygenase discovered with bioinformatics screening and its application in textile desizing

Authors: Meijuan Zhang, Xiaoping Fu, Rongrong Gu, Bohua Zhao, Xingya Zhao, Hui Song, Hongchen Zheng, Jianyong Xu, Wenqin Bai

Journal: BMC Biotechnol

PubMed ID: 38200466

Doi: 10.1186/s12896-023-00826-1

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Towards detection of structurally-diverse glycated epitopes in native proteins: Single-chain antibody directed to non-A1c epitope in human haemoglobin

Authors: Miss Lucia Gaetani, Isabel Campos Pinto, Meng Li, Peter O'Connor, Susan Giorgi-Coll, Matthew Tyreman, Katherine L Rumary, James A Schouten, Paul Davis, Ann M Dixon

Journal: Mol Immunol

PubMed ID: 38181455

Doi: 10.1016/j.molimm.2023.12.008

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Comparative immunogenicity and neutralizing antibody responses post heterologous vaccination with CoronaVac (Sinovac) and Vaxzevria (AstraZeneca) in HIV-infected patients with varying CD4+ T lymphocyte counts

Authors: Sorawit Chittrakarn, Pisud Siripaitoon, Sarunyou Chusri, Siripen Kanchanasuwan, Boonsri Charoenmak, Thanaporn Hortiwakul, Phaiwon Kantikit, Narongdet Kositpantawong

Journal: Hum Vaccin Immunother

PubMed ID: 38297904

Doi: 10.1080/21645515.2024.2309734

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PARP trapping is governed by the PARP inhibitor dissociation rate constant

Authors: Angelica A Gopal, Bianca Fernandez, Justin Delano, Ralph Weissleder, J Matthew Dubach

Journal: Cell Chem Biol

PubMed ID: 38262416

Doi: 10.1016/j.chembiol.2023.12.019

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Exploring a novel long-acting glucagon-like peptide-1 receptor agonist built on the albumin-binding domain and XTEN scaffolds

Authors: Yan Zhou, Jianhui Li, Guosheng Gao, Yafeng Li, Changzhen Zhang

Journal: Heliyon

PubMed ID: 38293540

Doi: 10.1016/j.heliyon.2024.e24340

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Improving and Streamlining Gene Editing in via Integration of Engineered Cas9 Protein

Authors: Baixi Zhang, Jiacan Cao

Journal: J Fungi (Basel)

PubMed ID: 38248972

Doi: 10.3390/jof10010063

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Tuning plasmid DNA amounts for cost-effective transfections of mammalian cells: when less is more

Authors: Aida Carreño, Rubén Guerrero-Yagüe, Enriqueta Casal, Rosa Mendoza, José Luis Corchero

Journal: Appl Microbiol Biotechnol

PubMed ID: 38212965

Doi: 10.1007/s00253-024-13003-x

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Lipopolysaccharides from a Shiraia fruiting body-associated bacterium elicit host fungal hypocrellin A biosynthesis through nitric oxide generation

Authors: Xin Ping Li , Wen Hao Shen , Lu Lu Zhou , Qun Yan Huang , Rui Peng Cong , Li Ping Zheng , Jian Wen Wang

Journal: Carbohydr Polym .

PubMed ID: 37985049

Doi: 10.1016/j.carbpol.2023.121498.

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Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes

Authors: Zebin Tong , Huasong Ai, Ziyu Xu , Kezhang He , Guo-Chao Chu, Qiang Shi , Zhiheng Deng, Qiaomei Xue , Maoshen Sun, Yunxiang Du , Lujun Liang, Jia-Bin Li , Man Pan , Lei Liu

Journal: Nat Struct Mol Biol .

PubMed ID: 38177667

Doi: 10.1038/s41594-023-01141-1

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Inhaled nanoparticles for treating idiopathic pulmonary fibrosis by inhibiting honeycomb cyst and alveoli interstitium remodeling

Authors: Meng-Meng Han , Ling Tang , Bin Huang , Xue-Na Li , Yue-Fei Fang , Liang Qi , Bo-Wen Duan , Ya-Ting Yao , Yu-Jing He , Lei Xing , Hu-Lin Jiang

Journal: J Control Release .

PubMed ID: 38242209

Doi: 10.1016/j.jconrel.2024.01.032

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Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation

Authors: Anlan Yang , Shengjie Liu , Yuqi Zhang , Jia Chen , Yujing Fan , Fengxiang Wang , Yilong Zou , Shan Feng , Jianping Wu , Qi Hu

Journal: Nat Struct Mol Biol .

PubMed ID: 38182928

Doi: 10.1038/s41594-023-01183-5

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Disordered-to-ordered transitions in assembly factors allow the complex II catalytic subunit to switch binding partners

Authors: Pankaj Sharma, Elena Maklashina, Markus Voehler, Sona Balintova , Sarka Dvorakova, Michal Kraus, Katerina Hadrava Vanova Zuzana Nahacka, Renata Zobalova, Stepana Boukalova, Kristyna Cunatova, Tomas Mracek, Hans K Ghayee, Karel Pacak, Jakub Rohlena, Jiri Neuzil, Gary Cecchini,T M Iverson

Journal: Nat Commun

PubMed ID: 38212624

Doi: 10.1038/s41467-023-44563-7

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MARS an improved de novo peptide candidate selection method for non-canonical antigen target discovery in cancer

Authors: Hanqing Liao , Carolina Barra , Zhicheng Zhou , Xu Peng , Isaac Woodhouse , Arun Tailor , Robert Parker , Alexia Carré , Persephone Borrow , Michael J Hogan , Wayne Paes , Laurence C Eisenlohr , Roberto Mallone , Morten Nielsen , Nicola Ternette

Journal: Nat Commun

PubMed ID: 38253617

Doi: 10.1038/s41467-023-44460-z

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The role of CD38 in inflammation-induced depression-like behavior and the antidepressant effect of (R)-ketamine

Authors: Xinying Zhang a , Teng He a , Zifeng Wu a , Yuanyuan Wang a, Hanyu Liu a, Bingyuan Zhang a, Siqi Yang a, Di Wang a, Chaoli Huang a, Jiahao Duan b, Xiangyang Xu c, Xiangqing Xu c, Kenji Hashimoto d, Riyue Jiang e, Ling Yang b, Chun Yang

Journal: Brain, behavior, and immunity

PubMed ID: 37793489

Doi: 10.1016/j.bbi.2023.09.026

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Acylspermidines are conserved mitochondrial sirtuin-dependent metabolites

Authors: Bingsen Zhang, James Mullmann, Andreas H. Ludewig, Irma R. Fernandez, Tyler R. Bales, Robert S. Weiss & Frank C. Schroeder

Journal: Nature Chemical Biology

PubMed ID: 38167917

Doi: 10.1038/s41589-023-01511-2

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Omicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue

Authors: Guoli Shi , Tiansheng Li , Kin Kui Lai , Reed F Johnson , Jonathan W Yewdell , Alex A Compton

Journal: Nat Commun

PubMed ID: 38291024

Doi: 10.1038/s41467-024-45075-8

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The role of the Toll like receptor 4 signaling in sex-specific persistency of depression-like behavior in response to chronic stress

Authors: Eun-Jeong Yang , Tal Frolinger , Umar Iqbal , Molly Estill , Li Shen , Kyle J Trageser , Giulio M Pasinetti

Journal: Brain, behavior, and immunity

PubMed ID: 37838079

Doi: 10.1016/j.bbi.2023.10.006

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Role of UPF1-LIN28A interaction during early differentiation of pluripotent stem cells

Authors: Seungwon Jung , Seung Hwan Ko , Narae Ahn , Jinsam Lee , Chang-Hwan Park , Jungwook Hwang

Journal: Nat Commun

PubMed ID: 38167913

Doi: 10.1038/s41467-023-44600-5

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Circ_0087199 depletion attenuates lipopolysaccharides-induced human periodontal ligament cell injury through the miR-527/TLR4 axis

Authors: Jing Wang , Na Huo , Chuan Cai , Yu Zhang, Rui Xiao

Journal: Immunity

PubMed ID: 38270303

Doi: 10.1002/iid3.1153

CI:Mor interactions in the lysogeny switches of TP901-1 and φ13 bacteriophages

Authors: Anders K Varming, Zhiyu Huang, Ghofran M Hamad, Kim K Rasmussen, Hanne Ingmer, Mogens Kilstrup, Leila Lo Leggio

Journal: Microbiome Res Rep

PubMed ID: 38841409

Doi: 10.20517/mrr.2023.50

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IGF-I protects porcine granulosa cells from hypoxia-induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway

Authors: Zhaojun Liu, Chungang Feng, Chengyu Li, Tong He, Gang Wu, Chen Fu, Hongmin Li, Ming Shen, Honglin Liu

Journal: FASEB J

PubMed ID: 38095232

Doi: 10.1096/fj.202301464R

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Engineering of Ogataea polymorpha strains with ability for high-temperature alcoholic fermentation of cellobiose

Authors: Roksolana Vasylyshyn, Olena Dmytruk, Andriy Sybirnyy, Justyna Ruchała

Journal: FEMS Yeast Res

PubMed ID: 38400543

Doi: 10.1093/femsyr/foae007

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FLUAV RAM-IGIP: A modified live influenza virus vaccine that enhances humoral and mucosal responses against influenza

Authors: C Joaquín Cáceres, L Claire Gay, Aarti Jain, Teresa D Mejías, Matias Cardenas, Brittany Seibert, Flavio Cargnin Faccin, Brianna Cowan, Ginger Geiger, Amy Vincent Baker, Silvia Carnaccini, D Huw Davies, Daniela S Rajao, Daniel R Perez

Journal: biorxiv

PubMed ID: 38328128

Doi: 10.1101/2024.01.23.576908

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Assessment of the effectiveness of the peptide inhibitor homologous to the transforming growth factor β cytokine blocking the TGFβRI/TGFβRII receptor complex-pilot study

Authors: Marynowski Mateusz, Karbownik Michał Seweryn, Szemraj Janusz, Kuna Piotr, Michał Gabriel Panek

Journal: Clin Transl Allergy

PubMed ID: 38282199

Doi: 10.1002/clt2.12320

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Cell death induced by nicotine in human neuroblastoma SH-SY5Y cells is mainly attributed to cytoplasmic vacuolation originating from the trans-Golgi network

Authors: Jun Li, Hongjuan Wang, Huan Chen, Xiao Li, Yong Liu, Hongwei Hou, Qingyuan Hu

Journal: Food Chem Toxicol

PubMed ID: 38176581

Doi: 10.1016/j.fct.2023.114431

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FLT3L-induced virtual memory CD8 T cells engage the immune system against tumors

Authors: Hsin-Fang Tu, Yu-Jui Kung, Ling Lim, Julia Tao, Ming-Hung Hu, Michelle Cheng, Deyin Xing, T C Wu, Chien-Fu Hung

Journal: J Biomed Sci

PubMed ID: 38287325

Doi: 10.1186/s12929-024-01006-9

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Structural, Biochemical, and Bioinformatic Basis for Identifying Radical SAM Cyclopropyl Synthases

Authors: Yi Lien, Jake C Lachowicz, Aigera Mendauletova, Cynthia Zizola, Thacien Ngendahimana, Anastasiia Kostenko, Sandra S Eaton, John A Latham, Tyler L Grove

Journal: ACS Chem Biol

PubMed ID: 38295270

Doi: 10.1021/acschembio.3c00583

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Rescue of secretion of rare-disease-associated misfolded mutant glycoproteins in UGGT1 knock-out mammalian cells

Authors: Gabor Tax, Kevin P Guay, Ludovica Pantalone, Martina Ceci, Tatiana Soldà, Charlie J Hitchman, Johan C Hill, Snežana Vasiljević, Andrea Lia, Carlos P Modenutti, Kees R Straatman, Angelo Santino, Maurizio Molinari, Nicole Zitzmann, Daniel N Hebert, Pietro Roversi, Marco Trerotola

Journal: Traffic

PubMed ID: 38272446

Doi: 10.1111/tra.12927

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GhUBC10-2 mediates GhGSTU17 degradation to regulate salt tolerance in cotton (Gossypium hirsutum)

Authors: Yaru Sun, Zailong Tian, Dongyun Zuo, Qiaolian Wang, Guoli Song

Journal: Plant Cell Environ

PubMed ID: 38282268

Doi: 10.1111/pce.14839

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factor H-binding proteins are not required for serum resistance and infection in mammals

Authors: Nicholas A Cramer, Kalya M Socarras, Joshua Earl, Garth D Ehrlich, Richard T Marconi

Journal: Infect Immun

PubMed ID: 38289123

Doi: 10.1128/iai.00529-23

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