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Using for High-Yield Production of Challenging Expression Targets and for Protein Perdeuteration

Authors: Natalia Mojica, Flore Kersten, Mateu Montserrat-Canals, G Robb Huhn Iii, Abelone M Tislevoll, Gabriele Cordara, Ken Teter, Ute Krengel

Journal: Biochemistry

PubMed ID: 38359344

Doi: 10.1021/acs.biochem.3c00612

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CRISPR Ribonucleoprotein-Mediated Precise Editing of Multiple Genes in Porcine Fibroblasts

Authors: Xiaochen Guo, Chang Liu, Yunjing Zhao, Chaoqian Jiang, Junxue Jin, Zhonghua Liu, Yanshuang Mu

Journal: Animals (Basel)

PubMed ID: 38396618

Doi: 10.3390/ani14040650

Products & Services: Gene Synthesis

Vaccine Based on Recombinant Fusion Protein Combining Hepatitis B Virus PreS with SARS-CoV-2 Wild-Type- and Omicron-Derived Receptor Binding Domain Strongly Induces Omicron-Neutralizing Antibodies in a Murine Model

Authors: Pia Gattinger, Bernhard Kratzer, Al Nasar Ahmed Sehgal, Anna Ohradanova-Repic, Laura Gebetsberger, Gabor Tajti, Margarete Focke-Tejkl, Mirjam Schaar, Verena Fuhrmann, Lukas Petrowitsch, Walter Keller, Sandra Högler, Hannes Stockinger, Winfried F Pickl, Rudolf Valenta

Journal: Vaccines (Basel)

PubMed ID: 38543863

Doi: 10.3390/vaccines12030229

Products & Services: Recombinant Proteins

NK-92MI Cells Engineered with Anti-claudin-6 Chimeric Antigen Receptors in Immunotherapy for Ovarian Cancer

Authors: Junping Li, Hong Hu, Hui Lian, Shuo Yang, Manting Liu, Jinping He, Bihui Cao, Dongni Chen, Yuling Hu, Chen Zhi, Yan Shen, Xiaodie Ye, Bingjia He, Ming Zhao, Weijun Fan, Linfeng Xu, Rom Leidner, Qingde Wu, Lili Yang, Zhenfeng Zhang

Journal: Int J Biol Sci

PubMed ID: 38481806

Doi: 10.7150/ijbs.88539

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NEAT1 repression by MED12 creates chemosensitivity in p53 wild-type breast cancer cells

Authors: Shengjie Zhang, Eui-Jun Kim, Junfeng Huang, Peng Liu, Kristine Donahue, Qinchuan Wang, Yidan Wang, Sean Mcilwain, Ling Xie, Xian Chen, Lingjun Li, Wei Xu

Journal: FEBS J

PubMed ID: 38380720

Doi: 10.1111/febs.17097

Products & Services: Proteins, Expression, Isolation and Analysis

Creation of a point-of-care therapeutics sensor using protein engineering, electrochemical sensing and electronic integration

Authors: Rong Cai, Chiagoziem Ngwadom, Ravindra Saxena, Jayashree Soman, Chase Bruggeman, David P Hickey, Rafael Verduzco, Caroline M Ajo-Franklin

Journal: Nat Commun

PubMed ID: 38402222

Doi: 10.1038/s41467-024-45789-9

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Polycomb repression of Hox genes involves spatial feedback but not domain compaction or phase transition

Authors: Sedona Eve Murphy, Alistair Nicol Boettiger

Journal: Nat Genet

PubMed ID: 38361032

Doi: 10.1038/s41588-024-01661-6

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Performance of Three Anti-SARS-CoV-2 Anti-S and One Anti-N Immunoassays for the Monitoring of Immune Status and Vaccine Response

Authors: Y Victoria Zhang, Attila Kumanovics, Joesph Wiencek, Stacy E F Melanson, Tanzy Love, Alan H B Wu, Zhen Zhao, Qing H Meng, David D Koch, Fred S Apple, Caitlin R Ondracek, Robert H Christenson

Journal: Viruses

PubMed ID: 38400067

Doi: 10.3390/v16020292

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Long noncoding RNA TMPO-AS1 accelerates glycolysis by regulating the miR-1270/PKM2 axis in colorectal cancer

Authors: Yingmin Jin, Aimin Jiang, Liying Sun, Yue Lu

Journal: BMC Cancer

PubMed ID: 38383342

Doi: 10.1186/s12885-024-11964-w

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CD46 and CD59 inhibitors enhance complement-dependent cytotoxicity of anti-CD38 monoclonal antibodies daratumumab and isatuximab in multiple myeloma and other B-cell malignancy cells

Authors: Hongjie Wang, Theo Koob, Jonathan R Fromm, Ajay Gopal, Darrick Carter, André Lieber

Journal: Cancer Biol Ther

PubMed ID: 38361357

Doi: 10.1080/15384047.2024.2314322

Products & Services: Proteins, Expression, Isolation and Analysis

Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase

Authors: Joshua J Maw, Jesse A Coker, Tarun Arya, Christopher M Goins, Dhiraj Sonawane, Sang Hoon Han, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Nancy S Wang, Hannelore V Heemers, Jonathan D Macdonald, Shaun R Stauffer

Journal: J Med Chem

PubMed ID: 38330278

Doi: 10.1021/acs.jmedchem.3c01807

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mTOR Regulates Mineralocorticoid Receptor Transcriptional Activity by ULK1-Dependent and -Independent Mechanisms

Authors: Yusuf Ali, Celso E Gomez-Sanchez, Maria Plonczynski, Aniko Naray-Fejes-Toth, Geza Fejes-Toth, Elise P Gomez-Sanchez

Journal: Endocrinology

PubMed ID: 38325289

Doi: 10.1210/endocr/bqae015

Products & Services: Proteins, Expression, Isolation and Analysis

Exploring the immunogenicity of Rv2201-519: A T-cell epitope-based antigen derived from Mycobacterium tuberculosis AsnB with implications for tuberculosis infection detection and vaccine development

Authors: Xiuli Luan, Xueting Fan, Guilian Li, Mchao Li, Na Li, Yuhan Yan, Xiuqin Zhao, Haican Liu, Kanglin Wan

Journal: Int Immunopharmacol

PubMed ID: 38342063

Doi: 10.1016/j.intimp.2024.111542

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Discovery of Two Novel Immunoepitopes and Development of Peptide-based Sarcoidosis Immunoassay

Authors: Changya Peng , Jaya Talreja , Brennen Steinbauer , Kazuhiko Shinki , Laura L Koth , Lobelia Samavati

Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

PubMed ID: 38385694

Doi: 10.1164/rccm.202306-1054OC

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Bicistronic expression of nuclear transgenes in Chlamydomonas reinhardtii

Authors: Nick Jacobebbinghaus, Kyle J Lauersen, Olaf Kruse, Thomas Baier

Journal: the plant journal

PubMed ID: 38415961

Doi: 10.1111/tpj.16677

Products & Services: Gene Synthesis

SPR spectroscopic analysis of myosin binding to wild type and mutant UNC45B

Authors: Silvana Valdebenito, Eliseo Eugenin, Andres Oberhauser

Journal: MicroPubl Biol

PubMed ID: 38404916

Doi: 10.17912/micropub.biology.001131

Products & Services: Recombinant Proteins

Architecture and flexibility of native kinetochores revealed by structural studies utilizing a thermophilic yeast

Authors: Daniel J Barrero, Sithara S Wijeratne, Xiaowei Zhao, Grace F Cunningham, Yan Rui, Christian R Nelson, Arimura Yasuhiro, Hironori Funabiki, Charles L Asbury, Zhiheng Yu, Radhika Subramanian, Sue Biggins

Journal: biorxiv

PubMed ID: 38464254

Doi: 10.1101/2024.02.28.582571

Products & Services: Recombinant Proteins

NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route

Authors: Obed Boadi Amissah, Wenfang Chen, Jean de Dieu Habimana, Yirong Sun, Lihui Lin, Yujie Liu, Ling Wang, Zhaoming Liu, Omar Mukama, Rajesh Basnet, Hohua Liu, Junyi Li, Xuanyan Ding, Lingshuang Lv, Min Chen, Yalin Liang, Rongqi Huang, Zhiyuan Li

Journal: Cancer Cell Int

PubMed ID: 38336680

Doi: 10.1186/s12935-024-03249-w

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CD39 tumor infiltrating T cells from colorectal cancers exhibit dysfunctional phenotype

Authors: Yuan Feng, Xin Xu, Jiaxin Zhang, Christopher Sanderson, Jun Xia, Zhang Bu, Yili Yang, Peng Yang, Zhiliang Lu

Journal: Am J Cancer Res

PubMed ID: 38455401

Doi: 10.62347/IZEN3736

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A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency

Authors: Felipe Guapo, Nicholas Donohue, Lisa Strasser, Stefano Boi, Florian Füssl, Alana Rainbow-Fletcher, Paul Getty, Ian Anderson, Niall Barron, Jonathan Bones

Journal: Int J Mol Sci

PubMed ID: 38474031

Doi: 10.3390/ijms25052785

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Seroprevalence of IgM/IgG and Neutralizing Antibodies against SARS-CoV-2 in Unvaccinated Young Adults from Mexico Who Reported Not Having Had a Previous COVID-19 Infection

Authors: Diana Lourdes Padilla-Bórquez, Mónica Guadalupe Matuz-Flores, Jorge Hernández-Bello, Gabriela Athziri Sánchez-Zuno, Samuel García-Arellano, Edith Oregon-Romero, Melva Guadalupe Herrera-Godina, Guillermo González-Estevez, Norma Patricia Adan-Bante, Jesús Alfredo Rosas-Rodríguez, José Francisco Muñoz-Valle

Journal: Can J Infect Dis Med Microbiol

PubMed ID: 38384428

Doi: 10.1155/2024/8871439

Products & Services: Proteins, Expression, Isolation and Analysis

Distinct structural variants and repeat landscape shape the genomes of the ancient grapes Aglianico and Falanghina

Authors: Riccardo Aversano, Marina Iovene , Salvatore Esposito , Alberto L'Abbate , Clizia Villano , Ermanno Di Serio , Maria Francesca Cardone , Carlo Bergamini , Riccardo Aiese Cigliano , Vincenzo D'Amelia , Luigi Frusciante , Domenico Carputo

Journal: BMC Plant Biol.

PubMed ID: 38317087

Doi: 10.1186/s12870-024-04778-2

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Structure-guided engineering enables E3 ligase-free and versatile protein ubiquitination via UBE2E1

Authors: Xiangwei Wu, Yunxiang Du, Lu-Jun Liang, Ruichao Ding, Tianyi Zhang, Hongyi Cai, Xiaolin Tian, Man Pan, Lei Liu

Journal: Nat Commun .

PubMed ID: 38341401

Doi: 10.1038/s41467-024-45635-y

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Mage Transposon: A Novel Gene Delivery System for Mammalian Cells

Authors: Jinghan Tian, Doudou Tong, Zhendong Li, Erqiang Wang, Yifei Yu, Hangya Lv, Zhendan Hu, Fang Sun, Guoping Wang, Min He, Tian Xia

Journal: Nucleic Acids Res .

PubMed ID: 38300794

Doi: 10.1093/nar/gkae048

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An oncolytic virus–T cell chimera for cancer immunotherapy

Authors: Yuxuan Chen , Xiaohong Chen , Weier Bao , Gang Liu , Wei Wei , Yuan Ping

Journal: Nat Biotechnol .

PubMed ID: 38336902

Doi: 10.1038/s41587-023-02118-7

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A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection

Authors: Lorena M Coria , Juan Manuel Rodriguez , Agostina Demaria , Laura A Bruno , Mayra Rios Medrano , Celeste Pueblas Castro , Eliana F Castro , Sabrina A Del Priore , Andres C Hernando Insua , Ingrid G Kaufmann , Lucas M Saposnik , William B Stone , Lineia Prado , Ulises S Notaro , Ayelen N Amweg , Pablo U Diaz , Martin Avaro , Hugo Ortega , Ana Ceballos , Valeria Krum , Francisco M Zurvarra , Johanna E Sidabra , Ignacio Drehe , Jonathan A Baqué , Mariana Li Causi , Analia V De Nichilo , Cristian J Payes , Teresa Southard , Julio C Vega , Albert J Auguste , Diego E Álvarez , Juan M Flo , Karina A Pasquevich , Juliana Cassataro

Journal: Nat Commun

PubMed ID: 38307851

Doi: 10.1038/s41467-024-45180-8

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The chromatin-associated lncREST ensures effective replication stress response by promoting the assembly of fork signaling factors

Authors: Luisa Statello , José Miguel Fernandez-Justel , Jovanna González , Marta Montes , Alessia Ranieri , Enrique Goñi , Aina M Mas , Maite Huarte

Journal: Nat Commun

PubMed ID: 38302450

Doi: 10.1038/s41467-024-45183-5

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Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1

Authors: Leon Tejwani, Neal G Ravindra, Changwoo Lee, Yubao Cheng, Billy Nguyen, Kimberly Luttik, Luhan Ni, Shupei Zhang, Logan M Morrison, John Gionco, Yangfei Xiang, Jennifer Yoon, Hannah Ro, Fatema Haidery, Rosalie M Grijalva, Eunwoo Bae, Kristen Kim , Regina T Martuscello, Harry T Orr, Huda Y Zoghbi , Hayley S McLoughlin, Laura P W Ranum, Vikram G Shakkottai, Phyllis L Faust, Siyuan Wang, David van Dijk, Janghoo Lim

Journal: Neuron

PubMed ID: 38016472

Doi: 10.1016/j.neuron.2023.10.039

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Discoveries of GPR39 as an evolutionarily conserved receptor for bile acids and of its involvement in biliary acute pancreatitis

Authors: Zhentao Zi 1 2, Yi Rao

Journal: Sci Adv

PubMed ID: 38306436

Doi: 10.1126/sciadv.adj0146

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Essential functions of Inositol hexakisphosphate (IP6) in Murine Leukemia Virus replication

Authors: Banhi Biswas, Kin Kui Lai, Harrison Bracey, Siddhartha A K Datta, Demetria Harvin, Gregory A Sowd, Christopher Aiken, Alan Rein

Journal: biorxiv

PubMed ID: 38464197

Doi: 10.1101/2024.02.27.581940

Products & Services: Proteins, Expression, Isolation and Analysis

Examination of SARS-CoV-2 serological test results from multiple commercial and laboratory platforms with an in-house serum panel

Authors: Sandra N Lester, Megan Stumpf, Brandi D Freeman, Lisa Mills, Jarad Schiffer, Vera Semenova, Tao Jia, Rita Desai, Peter Browning, Bailey Alston, Muyiwa Ategbole, Shanna Bolcen, Alexander Chen, Ebenezer David, Panagiotis Manitis, Heather Tatum, Yunlong Qin, Briana Zellner, Jan Drobeniuc, Alexandra Tejada-Strop, Payel Chatterjee, Punya Shrivastava-Ranjan, M Harley Jenks, Laura K McMullan, Mike Flint, Christina F Spiropoulou, Glenn P Niemeyer, Bonnie J Werner, Christopher J Bean, Jeffrey A Johnson, Alex R Hoffmaster, Panayampalli S Satheshkumar, Amy J Schuh, S Michele Owen, Natalie J Thornburg

Journal: Access Microbiol

PubMed ID: 38482357

Doi: 10.1099/acmi.0.000463.v4

Products & Services: Proteins, Expression, Isolation and Analysis

Efficient production of 2'-fucosyllactose from fructose through metabolically engineered recombinant Escherichia coli

Authors: Ran You, Lei Wang, Meirong Hu, Yong Tao

Journal: Microb Cell Fact

PubMed ID: 38303005

Doi: 10.1186/s12934-024-02312-5

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Chimeric antigen receptor T cells targeting the GM3(Neu5Gc) ganglioside

Authors: Julia Heinzelbecker, Marte Fauskanger, Ida Jonson, Ute Krengel, Geir Åge Løset, Ludvig Munthe, Anders Tveita

Journal: Front Immunol

PubMed ID: 38370401

Doi: 10.3389/fimmu.2024.1331345

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The expression of genes encoding novel Sesame oleosin variants facilitates enhanced triacylglycerol accumulation in Arabidopsis leaves and seeds

Authors: Sanket Anaokar, Yuanxue Liang, Xiao-Hong Yu, Yingqi Cai, Yuanheng Cai, John Shanklin

Journal: New Phytol

PubMed ID: 38329350

Doi: 10.1111/nph.19548

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A Cancer Nanovaccine for Co-Delivery of Peptide Neoantigens and Optimized Combinations of STING and TLR4 Agonists

Authors: Jessalyn J. Baljon, Alexander J. Kwiatkowski, Hayden M. Pagendarm, Payton T. Stone, Amrendra Kumar, Vijaya Bharti, Jacob A. Schulman, Kyle W. Becker, Eric W. Roth, Plamen P. Christov, Sebastian Joyce, and John T. Wilson*

Journal: ACS Nano

PubMed ID: 38386282

Doi: 10.1021/acsnano.3c04471

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Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA. 2.86 and FLip variants

Authors: Panke Qu 1, Kai Xu 1, Julia N Faraone 2, Negin Goodarzi 1, Yi-Min Zheng 1, Claire Carlin 3, Joseph S Bednash 4, Jeffrey C Horowitz 4, Rama K Mallampalli 4, Linda J Saif 5, Eugene M Oltz 6, Daniel Jones 7, Richard J Gumina 8, Shan-Lu Liu

Journal: Cell

PubMed ID: 38194968

Doi: 10.1016/j.cell.2023.12.026

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An Antioxidative and Active Shrinkage Hydrogel Integratedly Promotes Re-Epithelization and Skin Constriction for Enhancing Wound Closure

Authors: Jiacheng Sun, Wang Jia, Hedong Qi, Jiawei Huo, Xiaodan Liao, Yuan Xu, Jun Wang, Zihao Sun, Yang Liu, Jingchao Liu, Mingming Zhen, Chunru Wang, Chunli Bai

Journal: Adv Mater

PubMed ID: 38332741

Doi: 10.1002/adma.202312440

Products & Services: Proteins, Expression, Isolation and Analysis

Imaging of extracellular and intracellular ATP in pancreatic beta cells reveals correlation between glucose metabolism and purinergic signalling

Authors: Seyed M Ghiasi, Nynne M Christensen, Per A Pedersen, Emil Z Skovhøj, Ivana Novak

Journal: Cell Signal

PubMed ID: 38373668

Doi: 10.1016/j.cellsig.2024.111109

Products & Services: Proteins, Expression, Isolation and Analysis

Unveiling PET Hydrolase Surface Dynamics through Fluorescence Microscopy

Authors: A P Rennison, A Nousi, P Westh, R Marie, M S Møller

Journal: Chembiochem

PubMed ID: 38224131

Doi: 10.1002/cbic.202300661

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Exploring the ATG9A interactome uncovers interaction with VPS13A

Authors: Alexander R van Vliet, Harold B J Jefferies, Peter A Faull, Jessica Chadwick, Fairouz Ibrahim, Mark J Skehel, Sharon A Tooze

Journal: J Cell Sci

PubMed ID: 38294121

Doi: 10.1242/jcs.261081

Products & Services: Proteins, Expression, Isolation and Analysis

Phospho-eIF4E stimulation regulates coronavirus entry by selective expression of cell membrane-residential factors

Authors: Xiu-Zhong Zhang, Jing Wang, Wen-Jun Tian, Jing-Ling You, Xiao-Jing Chi, Xiao-Jia Wang

Journal: J Virol

PubMed ID: 38299843

Doi: 10.1128/jvi.01948-23

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KNL1 and NDC80 represent new universal markers for the detection of functional centromeres in plants

Authors: Ludmila Oliveira, Pavel Neumann, Yennifer Mata-Sucre, Yi-Tzu Kuo, André Marques, Veit Schubert, Jiří Macas

Journal: Chromosome Res

PubMed ID: 38403686

Doi: 10.1007/s10577-024-09747-x

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Precise fine-turning of GhTFL1 by base editing tools defines ideal cotton plant architecture

Authors: Guanying Wang, Fuqiu Wang, Zhongping Xu, Ying Wang, Can Zhang, Yi Zhou, Fengjiao Hui, Xiyan Yang, Xinhui Nie, Xianlong Zhang, Shuangxia Jin

Journal: Genome Biol

PubMed ID: 38409014

Doi: 10.1186/s13059-024-03189-8

Plum blossom low molecular weight polypeptide protects HaCaT cells against UVB-induced oxidative damage in vitro and underlying mechanism

Authors: Zhixiong Chen, Ping Cao, Tingheng Zhu, Cui Yan, Zhongbo Zheng, Hong Yao

Journal: Skin Res Technol

PubMed ID: 38282275

Doi: 10.1111/srt.13582

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Supplementation of citrus pectin with whole-cell pectinase PG5 on Pichia pastoris promotes recovery of colitis and enhances intestinal barrier function in DSS-treated mice

Authors: Li Zhang, Jing Ren, Tianfei Yu, Yuanrong Li, Yanshun Li, Shuang Lu, Xiaohua Guo

Journal: Int J Biol Macromol

PubMed ID: 38428761

Doi: 10.1016/j.ijbiomac.2024.130476

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Recombinant Rod Domain of Vimentin Reduces SARS-CoV-2 Viral Replication by Blocking Spike Protein-ACE2 Interactions

Authors: Fong Wilson Lam, Cameron August Brown, Shannon Elizabeth Ronca

Journal: Int J Mol Sci

PubMed ID: 38473724

Doi: 10.3390/ijms25052477

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Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells

Authors: Mohammad Mahdi Hasani-Sadrabadi, Fatemeh S Majedi, Jana Zarubova, Timothy J Thauland, Vaithilingaraja Arumugaswami, Tzung K Hsiai, Louis-S Bouchard, Manish J Butte, Song Li

Journal: ACS Nano

PubMed ID: 38381620

Doi: 10.1021/acsnano.3c08559

Products & Services: Proteins, Expression, Isolation and Analysis

A novel vaccine strategy using quick and easy conversion of bacterial pathogens to unnatural amino acid-auxotrophic suicide derivatives

Authors: Yuya Nagasawa, Momoko Nakayama, Yusuke Kato, Yohsuke Ogawa, Swarmistha Devi Aribam, Yusaku Tsugami, Taketoshi Iwata, Osamu Mikami, Aoi Sugiyama, Megumi Onishi, Tomohito Hayashi, Masahiro Eguchi

Journal: Microbiol Spectr

PubMed ID: 38385737

Doi: 10.1128/spectrum.03557-23

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Structure of the recombinant RNA polymerase from African Swine Fever Virus

Authors: Simona Pilotto, Michal Sýkora, Gwenny Cackett, Christopher Dulson, Finn Werner

Journal: Nat Commun

PubMed ID: 38383525

Doi: 10.1038/s41467-024-45842-7

Products & Services: Proteins, Expression, Isolation and Analysis

Impact of Antenatal SARS-CoV-2 Exposure on SARS-CoV-2 Neutralization Potency

Authors: Chia-Jung Chiang, Wei-Lun Hsu, Mei-Tsz Su, Wen-Chien Ko, Keng-Fu Hsu, Pei-Yin Tsai

Journal: Vaccines (Basel)

PubMed ID: 38400147

Doi: 10.3390/vaccines12020164

Products & Services: Proteins, Expression, Isolation and Analysis

Chronic exposure to parabens promotes non-alcoholic fatty liver disease in association with the changes of the gut microbiota and lipid metabolism

Authors: Yilin Ren, Xinyi Shi, Jing Mu, Shenyin Liu, Xin Qian, Wenlong Pei, Shanhong Ni, Zhengduo Zhang, Lei Li, Zhan Zhang

Journal: Food Funct

PubMed ID: 38236135

Doi: 10.1039/d3fo04347a

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Contribution of to Docosahexaenoic Acid (DHA) Synthesis at the Transcriptional Regulation Level in Common Carp,

Authors: Hanyuan Zhang, Peizhen Li, Youxiu Zhu, Yanliang Jiang, Jianxin Feng, Zixia Zhao, Jian Xu

Journal: Animals (Basel)

PubMed ID: 38396511

Doi: 10.3390/ani14040544

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Extracellular vesicles incorporating retrovirus-like capsids for the enhanced packaging and systemic delivery of mRNA into neurons

Authors: Wenchao Gu, Sijin Luozhong, Simian Cai, Ketaki Londhe, Nadine Elkasri, Robert Hawkins, Zhefan Yuan, Kai Su-Greene, Yujie Yin, Margaret Cruz, Yu-Wei Chang, Patrick McMullen, Chunyan Wu, Changwoo Seo, Akash Guru, Wenting Gao, Tara Sarmiento, Chris Schaffer, Nozomi Nishimura, Richard Cerione, Qiuming Yu, Melissa Warden, Robert Langer, Shaoyi Jiang

Journal: Nat Biomed Eng

PubMed ID: 38374224

Doi: 10.1038/s41551-023-01150-x

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Characterization of core oligosaccharide synthesis reveals novel aspects of lipooligosaccharide assembly

Authors: Leah M VanOtterloo, Luis A Macias, Matthew J Powers, Jennifer S Brodbelt, M Stephen Trent

Journal: MBio

PubMed ID: 38349180

Doi: 10.1128/mbio.03013-23

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Comparative analysis of tuberculin and defined antigen skin tests for detection of bovine tuberculosis in buffaloes (Bubalus bubalis) in Haryana state, India

Authors: Mohit Kumar, Tarun Kumar, Babu Lal Jangir, Mahavir Singh, Devan Arora, Yogesh Bangar, Andrew Conlan, Martin Vordermeier, Douwe Bakker, S M Byregowda, Sreenidhi Srinivasan, Vivek Kapur, Naresh Jindal

Journal: BMC Vet Res

PubMed ID: 38395846

Doi: 10.1186/s12917-024-03913-3

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Oral administration of DNA alginate nanovaccine induced immune-protection against Helicobacter pylori in Balb/C mice

Authors: Arezo Kaveh-Samani, Samaneh Dalali, Fatemeh Kaviani, Tohid Piri-Gharaghie, Abbas Doosti

Journal: BMC Immunol

PubMed ID: 38310250

Doi: 10.1186/s12865-024-00602-6

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Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation

Authors: Yue Liu, Zhihui Zhang, Hongmiao Hu, Wei Chen, Fan Zhang, Qian Wang, Changshi Wang, Kaige Yan, Jiamu Du

Journal: Nat Plants

PubMed ID: 38413824

Doi: 10.1038/s41477-024-01640-z

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Improving the Efficiency of CRISPR Ribonucleoprotein-Mediated Precise Gene Editing by Small Molecules in Porcine Fibroblasts

Authors: Yunjing Zhao, Xinyu Li, Chang Liu, Chaoqian Jiang, Xiaochen Guo, Qianqian Xu, Zhi Yin, Zhonghua Liu, Yanshuang Mu

Journal: Animals (Basel)

PubMed ID: 38473105

Doi: 10.3390/ani14050719

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Elucidating the Signal Transduction Mechanism of the Blue-Light-Regulated Photoreceptor YtvA: From Photoactivation to Downstream Regulation

Authors: YongLe He, Jinnette Tolentino Collado, James N Iuliano, Helena A Woroniecka, Christopher R Hall, Agnieszka A Gil, Sergey P Laptenok, Gregory M Greetham, Boris Illarionov, Adelbert Bacher, Markus Fischer, Jarrod B French, Andras Lukacs, Stephen R Meech, Peter J Tonge

Journal: ACS Chemical Biology

PubMed ID: 38385342

Doi: 10.1021/acschembio.3c00722

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Long noncoding RNA ABHD11-AS1 interacts with SART3 and regulates CD44 RNA alternative splicing to promote lung carcinogenesis

Authors: Po-Shun Wang, Zulong Liu, Osama Sweef, Jie Xie, Jing Chen, Haining Zhu, Patti C Zeidler-Erdely, Chengfeng Yang, Zhishan Wang

Journal: Environ Int

PubMed ID: 38364571

Doi: 10.1016/j.envint.2024.108494

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ANGPTL4 regulates ovarian cancer progression by activating the ERK1/2 pathway

Authors: Jiaqi Xu, Fei Wu, Yue Zhu, Tiantian Wu, Tianyue Cao, Wenxin Gao, Meng Liu, Weifeng Qian, Guannan Feng, Xiaoxue Xi, Shunyu Hou

Journal: Cancer Cell Int

PubMed ID: 38311733

Doi: 10.1186/s12935-024-03246-z

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The 3-hydroxyacyl-CoA dehydratase 1/2 form complex with trans-2-enoyl-CoA reductase involved in substrates transfer in very long chain fatty acid elongation

Authors: Youli Zhou, Rui Lv, Richard D Ye, Ruobing Ren, Leiye Yu

Journal: Biochem Biophys Res Commun

PubMed ID: 38422897

Doi: 10.1016/j.bbrc.2024.149588

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Efficient Expression and Characterization of an Endo-Type Lyase HCLase_M28 and Its Gradual Scale-Up Fermentation for the Preparation of Chondroitin Sulfate Oligosaccharides

Authors: Ruibao Ju, Baoqin Han, Feng Han, Yanfei Peng

Journal: Appl Biochem Biotechnol

PubMed ID: 38386140

Doi: 10.1007/s12010-024-04878-7

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Design and development of multiepitope chimeric antigens by bioinformatic and bacterial based recombinant expression methods, with potential application for bovine tuberculosis serodiagnosis

Authors: Cassiano Martin Batista, Josir Laine Veschi, Vanessa Felipe de Souza, Leonardo Foti, Lea Chapaval Andri

Journal: Vet Immunol Immunopathol

PubMed ID: 38377627

Doi: 10.1016/j.vetimm.2024.110729

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Functional analyses of TRAF6 gene in Argopecten scallops

Authors: Xiaotong Zhang, Xia Wang, Jieyu Chen, Min Chen, Xia Lu, Junhao Ning, Haijun Liu, Guilong Liu, Xin Xu, Xiaoxu Qu, Kai Yu, He Xu, Chunde Wang, Bo Liu

Journal: Fish Shellfish Immunol

PubMed ID: 38354964

Doi: 10.1016/j.fsi.2024.109443

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Deficiency in PHD2-mediated hydroxylation of HIF2α underlies Pacak-Zhuang syndrome

Authors: Fraser G Ferens, Cassandra C Taber, Sarah Stuart, Mia Hubert, Daniel Tarade, Jeffrey E Lee, Michael Ohh

Journal: Commun Biol

PubMed ID: 38418569

Doi: 10.1038/s42003-024-05904-4

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Comparison of Cas12a and Cas9-mediated mutagenesis in tomato cells

Authors: Ellen Slaman, Lisanne Kottenhagen, William de Martines, Gerco C Angenent, Ruud A de Maagd

Journal: Sci Rep

PubMed ID: 38402312

Doi: 10.1038/s41598-024-55088-4

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Crossprotection induced by virus-like particles containing influenza dual-hemagglutinin and M2 ectodomain

Authors: Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Min-Ju Kim, Ki-Back Chu, Hae-Ji Kang, Fu-Shi Quan

Journal: Nanomedicine (Lond)

PubMed ID: 38390688

Doi: 10.2217/nnm-2023-0353

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Pharmacogenomics of poor drug metabolism in greyhounds: Canine P450 oxidoreductase genetic variation, breed heterogeneity, and functional characterization

Authors: Stephanie E Martinez, Amit V Pandey, Tania E Perez Jimenez, Zhaohui Zhu, Michael H Court

Journal: PLoS ONE

PubMed ID: 38300925

Doi: 10.1371/journal.pone.0297191

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Establishment of a Dual-Vector System for Gene Delivery Utilizing Prototype Foamy Virus

Authors: Soo-Yeon Cho, Yoon Jae Lee, Seong-Mook Jung, Young Min Son, Cha-Gyun Shin, Eui Tae Kim, Kyoung-Dong Kim

Journal: J Microbiol Biotechnol

PubMed ID: 38379304

Doi: 10.4014/jmb.2312.12026

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A diffusible small-RNA-based Turing system dynamically coordinates organ polarity

Authors: Emanuele Scacchi, Gael Paszkiewicz, Khoa Thi Nguyen, Shreyas Meda, Agata Burian, Walter de Back, Marja C P Timmermans

Journal: Nat Plants

PubMed ID: 38409292

Doi: 10.1038/s41477-024-01634-x

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Critical Aggregation Concentration Can be a Predictor of Doxorubicin Delivery Performance of Self-Assembling Amphiphilic Peptides with Different Hydrophobic Tails

Authors: Saeed Zanganeh, Loghman Firoozpour, Maryam Samareh Salavatipour, Soroush Sardari, Reza Ahangari Cohan, Nasir Mohajel

Journal: J Pharm Sci

PubMed ID: 38417791

Doi: 10.1016/j.xphs.2024.02.022

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Long-Term Dynamic Changes in Hybrid Immunity over Six Months after Inactivated and Adenoviral Vector Vaccination in Individuals with Previous SARS-CoV-2 Infection

Authors: Nungruthai Suntronwong, Sitthichai Kanokudom, Chompoonut Auphimai, Thanunrat Thongmee, Suvichada Assawakosri, Preeyaporn Vichaiwattana, Ritthideach Yorsaeng, Thaneeya Duangchinda, Warangkana Chantima, Pattarakul Pakchotanon, Pornjarim Nilyanimit, Donchida Srimuan, Thaksaporn Thatsanathorn, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Yong Poovorawan

Journal: Vaccines (Basel)

PubMed ID: 38400163

Doi: 10.3390/vaccines12020180

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A Divalent Chikungunya and Zika Nanovaccine with Thermostable Self-Assembly Multivalent Scaffold LS-SUMO

Authors: Qianlin Li, Jinsong Zhang, Qiang Deng, Conghui Liao, Jun Qian, Zeliang Chen, Jiahai Lu

Journal: Adv Healthc Mater

PubMed ID: 38340040

Doi: 10.1002/adhm.202303619

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Involvement of a catalase gene in lignin catalysis and immune defense against pathogenic fungus in Coptotermes formosanus: a potential new target for termite control

Authors: Wenhui Zeng, Danni Shen, Wenjing Wu, Shijun Zhang, Zhiqiang Li, Dandan Zhang

Journal: Pest Manag Sci

PubMed ID: 38358092

Doi: 10.1002/ps.8029

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Deciphering the origin of developmental stability: The role of intracellular expression variability in evolutionary conservation

Authors: Yui Uchida, Masato Tsutsumi, Shunsuke Ichii, Naoki Irie, Chikara Furusawa

Journal: Evol Dev

PubMed ID: 38414112

Doi: 10.1111/ede.12473

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Inhibition of Aurora Kinase Induces Endogenous Retroelements to Induce a Type I/III IFN Response via RIG-I

Authors: Lisa Choy, Stephen Norris, Xiumin Wu, Ganesh Kolumam, Ari Firestone, Jeffrey Settleman, David Stokoe

Journal: Cancer Res Commun

PubMed ID: 38358346

Doi: 10.1158/2767-9764.CRC-23-0432

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CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy

Authors: Peixia Tang , Zhen Yu , Hao Sun 2, Lanting Liu , Lixin Gong , Teng Fang , Xiyue Sun , Shiyi Xie , Gang An 2, Zhenshu Xu 3, Lugui Qiu 4, Mu Hao

Journal: EBioMedicine

PubMed ID: 38199044

Doi: 10.1016/j.ebiom.2023.104961

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Heterotypic interactions can drive selective co-condensation of prion-like low-complexity domains of FET proteins and mammalian SWI/SNF complex

Authors: Richoo B Davis, Anushka Supakar, Aishwarya Kanchi Ranganath, Mahdi Muhammad Moosa, Priya R Banerjee

Journal: Nature Communications

PubMed ID: 38326345

Doi: 10.1038/s41467-024-44945-5

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Increasing β-hexosaminidase A activity using genetically modified mesenchymal stem cells

Authors: Alisa A Shaimardanova , Daria S Chulpanova , Valeriya V Solovyeva 1, Shaza S Issa , Aysilu I Mullagulova , Angelina A Titova , Yana O Mukhamedshina , Anna V Timofeeva , Alexander M Aimaletdinov , Islam R Nigmetzyanov , Albert A Rizvanov

Journal: Neural Regen Res .

PubMed ID: 37488869

Doi: 10.4103/1673-5374.375328

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Minimalist Nanovaccine with Optimized Amphiphilic Copolymers for Cancer Immunotherapy

Authors: Le Niu , Yu Miao , Zhiqin Cao , Ting Wei , Jiafei Zhu , Maoyi Li , Boxiong Bai , Linfu Chen , Nanhui Liu , Feng Pan , Junjie Zhu , Cheng Wang , Yang Yang , Qian Chen

Journal: ACS Nano .

PubMed ID: 38230639

Doi: 10.1021/acsnano.3c10174

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Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide

Authors: Tian Xie , Feitong Dong , Gongshe Han , Xinyue Wu , Peng Liu , Zike Zhang , Jianlong Zhong , Somashekarappa Niranjanakumari , Kenneth Gable , Sita D Gupta , Wenchen Liu , Peter J Harrison , Dominic J Campopiano , Teresa M Dunn , Xin Gong

Journal: Cell Rep .

PubMed ID: 38285738

Doi: 10.1016/j.celrep.2024.113717

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Supramolecular Hydrogel with Ultra-Rapid Cell-Mediated Network Adaptation for Enhancing Cellular Metabolic Energetics and Tissue Regeneration

Authors: Zhuo Li, Boguang Yang, Zhengmeng Yang, Xian Xie, Zhengnan Guo, Jianyang Zhao, Ruinan Wang, Hao Fu, Pengchao Zhao, Xin Zhao, Guosong Chen, Gang Li, Fuxin Wei, Liming Bian

Journal: Adv Mater .

PubMed ID: 38295393

Doi: 10.1002/adma.202307176

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TREM2 variants that cause early dementia and increase Alzheimer's disease risk affect gene splicing

Authors: Kostantin Kiianitsa, Maria E Lukes, Brian J Hayes, Julianna Brutman, Paul N Valdmanis, Thomas D Bird, Wendy H Raskind, Olena Korvatska

Journal: Brain

PubMed ID: 38226698

Doi: 10.1093/brain/awae014

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mRNA vaccines against SARS-CoV-2 induce divergent antigen-specific T-cell responses in patients with lung cancer

Authors: No-Joon Song, Karthik B Chakravarthy, Hyeongseon Jeon, Chelsea Bolyard, Kelsi Reynolds, Kevin P Weller, Sarah Reisinger, Yi Wang, Anqi Li, Sizun Jiang, Qin Ma, Dan H Barouch, Mark P Rubinstein, Peter G Shields, Eugene M Oltz, Dongjun Chung, Zihai Li

Journal: J Immunother Cancer

PubMed ID: 38177076

Doi: 10.1136/jitc-2023-007922

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Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis

Authors: Xiao-Yu Ji, Yu-Xin Guo, Li-Bin Wang, Wen-Cheng Wu, Jia-Qi Wang, Jin He, Rui Gao, Javad Rasouli, Meng-Yuan Gao, Zhen-Hai Wang, Dan Xiao, Wei-Feng Zhang, Bogoljub Ciric, Yuan Zhang, Xing Li

Journal: J Neuroinflammation

PubMed ID: 38246987

Doi: 10.1186/s12974-024-03019-5

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A CRISPR-Cas12a-based electrochemical biosensor for the detection of microphthalmia-associated transcription factor

Authors: Qisheng Luo, Chunyuan Zhang, Xiandong Deng, Dongyuan Liu, Xingchen Pan, Yuanxun Gong, Qianli Tang, Kai Zhang, Xianjiu Liao

Journal: Mikrochim Acta

PubMed ID: 38170285

Doi: 10.1007/s00604-023-06164-5

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Cognitive impairment is associated with BDNF-TrkB signaling mediating synaptic damage and reduction of amino acid neurotransmitters in heart failure

Authors: Lei Wang, Ziwen Lu, Yu Teng, Weibing Pan, Yang Li, Sha Su, Jingling Chang, Mingjing Zhao

Journal: FASEB J

PubMed ID: 38085181

Doi: 10.1096/fj.202301699RR

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Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket

Authors: Chia Ying Huang, Alexander Metz, Roland Lange, Nadia Artico, Céline Potot, Julien Hazemann, Manon Müller, Marina Dos Santos, Alain Chambovey, Daniel Ritz, Deniz Eris, Solange Meyer, Geoffroy Bourquin, May Sharpe, Aengus Mac Sweeney

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 38289714

Doi: 10.1107/S2059798324000329

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Structural basis of prostaglandin efflux by MRP4

Authors: Sergei Pourmal, Evan Green, Ruchika Bajaj, Ilan E Chemmama, Giselle M Knudsen, Meghna Gupta, Andrej Sali, Yifan Cheng, Charles S Craik, Deanna L Kroetz, Robert M Stroud

Journal: Nat Struct Mol Biol

PubMed ID: 38216659

Doi: 10.1038/s41594-023-01176-4

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Beta-1,3-Glucan-Binding Protein Inhibits Dengue and ZIKA Virus Replication

Authors: Xiaoxue Xie, Di Wang, Bo Li, Guorui Liang, Xiaoli Chen, Dan Xing, Teng Zhao, Xinyu Zhou, Chunxiao Li

Journal: Biomedicines

PubMed ID: 38255195

Doi: 10.3390/biomedicines12010088

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Increasing the Pentose Phosphate Pathway Flux to Improve Plasmid DNA Production in Engineered

Authors: Mitzi de la Cruz, Flavio Kunert, Hilal Taymaz-Nikerel, Juan-Carlos Sigala, Guillermo Gosset, Jochen Büchs, Alvaro R Lara

Journal: Microorganisms

PubMed ID: 38257977

Doi: 10.3390/microorganisms12010150

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Identification and application of an exocarp-preferential promoter for genetic engineering of tomato fruit

Authors: Xue-Ming Ruan, Xiangyu Xiong, Jian-Feng Li

Journal: Hortic Res

PubMed ID: 38544552

Doi: 10.1093/hr/uhae035

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Cluster-Enhanced Nanopore Sensing of Ovarian Cancer Marker Peptides in Urine

Authors: Thomas W Rockett, Mohammed Almahyawi, Madhav L Ghimire, Aashna Jonnalagadda, Victoria Tagliaferro, Sarah J Seashols-Williams, Massimo F Bertino, Gregory A Caputo, Joseph E Reiner

Journal: ACS Sens

PubMed ID: 38286995

Doi: 10.1021/acssensors.3c02207

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Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines

Authors: Roizza Beth So, Gang Li, Victoria Brentville, Janet M Daly, James E Dixon

Journal: J Control Release

PubMed ID: 38244841

Doi: 10.1016/j.jconrel.2024.01.031

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Therapeutic effect of long-acting FGF21 with controlled site-specific modification on nonalcoholic steatohepatitis

Authors: Jianying Qi, Zhimou Guo, Shenglong Zhu, Xuan Jiang, Yuanyuan Wu, Yingli Chen, Fei Hu, Jingjing Xiong, YunZhou Wu, Xianlong Ye, Xinmiao Liang

Journal: Int J Biol Macromol

PubMed ID: 38290625

Doi: 10.1016/j.ijbiomac.2024.129797

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Oleuropein-driven reprogramming of the myeloid cell compartment to sensitise tumours to PD-1/PD-L1 blockade strategies

Authors: Ester Blanco, Noelia Silva-Pilipich, Ana Bocanegra, Luisa Chocarro, Antonio Procopio, Karina Ausín, Joaquín Fernandez-Irigoyen, Leticia Fernández, Nerea Razquin, Ana Igea, Maider Garnica, Miriam Echaide, Hugo Arasanz, Ruth Vera, David Escors, Cristian Smerdou, Grazyna Kochan

Journal: Br J Cancer

PubMed ID: 38195888

Doi: 10.1038/s41416-023-02561-y

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Glyoxylate reductase: Definitive identification in human liver mitochondria, its importance for the compartment-specific detoxification of glyoxylate

Authors: Sander F Garrelfs, Serhii Chornyi, Heleen Te Brinke, Jos Ruiter, Jaap Groothoff, Ronald J A Wanders

Journal: J Inherit Metab Dis

PubMed ID: 38200664

Doi: 10.1002/jimd.12711

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Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer

Authors: Giuseppe Rospo, Rosaria Chilà, Vittoria Matafora, Veronica Basso, Simona Lamba, Alice Bartolini, Angela Bachi, Federica Di Nicolantonio, Anna Mondino, Giovanni Germano, Alberto Bardelli

Journal: Genome Med

PubMed ID: 38243308

Doi: 10.1186/s13073-023-01275-3

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Hepatitis C virus E1 recruits high-density lipoprotein to support infectivity and evade antibody recognition

Authors: Jennifer Casiano Matos, Kaneemozhe Harichandran, Jingrong Tang, Denis O Sviridov, Giacomo Sidoti Migliore, Motoshi Suzuki, Lisa R Olano, Alvaro Hobbs, Ashish Kumar, Myeisha U Paskel, Mattia Bonsignori, Altaira D Dearborn, Alan T Remaley, Joseph Marcotrigiano

Journal: J Virol

PubMed ID: 38174935

Doi: 10.1128/jvi.00849-23

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