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Tight Junction Component Occludin Binds to FIP5 to Regulate Endosome Trafficking and Mitotic Spindle Function

Authors: Zichao Zhang , Jing Chen , Rongze Ma , Chongshen Xu , Yunzhe Lu , Jiecan Zhou , Kun Xia , Pengfei Lu

Journal: Adv Sci (Weinh)

PubMed ID: 38884279

Doi: 10.1002/advs.202308822

Products & Services: Recombinant Proteins

A bispecific antibody exhibits broad neutralization against SARS-CoV-2 Omicron variants XBB.1.16, BQ.1.1 and sarbecoviruses

Authors: Yingdan Wang # 1 2, Aihua Hao # 1, Ping Ji # 1, Yunping Ma # 1 3, Zhaoyong Zhang # 4, Jiali Chen 1, Qiyu Mao 1, Xinyi Xiong 4, Palizhati Rehati 1, Yajie Wang 1, Yanqun Wang 4, Yumei Wen 1, Lu Lu 1, Zhenguo Chen 1, Jincun Zhao 5 6, Fan Wu 7, Jinghe Huang 8 9, Lei Sun 10

Journal: Nat Commun

PubMed ID: 38879565

Doi: 10.1038/s41467-024-49096-1

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Molecular recognition of the atypical chemokine-like peptide GPR15L by its cognate receptor GPR15

Authors: Zhongyuan Zhang , You Zheng , Lu Xu , Yang Yue , Kexin Xu , Fei Li 1, Fei Xu

Journal: Cell Discov

PubMed ID: 38918398

Doi: 10.1038/s41421-024-00698-5

Products & Services: Peptide Synthesis

The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer

Authors: Pengfei Yan , Xi Lin , Lijie Wu , Lu Xu , Fei Li , Junlin Liu , Fei Xu

Journal: Nat Commun

PubMed ID: 38898050

Doi: 10.1038/s41467-024-49625-y

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Development of GPC3-CAR-NK cells and optimization as a therapy for HCC

Authors: Bihui Cao, Qianqian Ni, Zhuxin Chen, Shuo Yang, Xinkui Zhang, Haotao Su, Zhenfeng Zhang, Qi Zhao, Xiaolan Zhu, Manting Liu

Journal: J Leukoc Biol

PubMed ID: 38922297

Doi: 10.1093/jleuko/qiae144

Products & Services: Molecular Biology Reagents

Androgen-responsive FOXP4 is a target for endometrial carcinoma

Authors: Kayo Kayahashi, Mahadi Hasan, Anowara Khatun, Susumu Kohno, Jumpei Terakawa, Shin-Ichi Horike, Natsumi Toyoda, Ayumi Matsuoka, Takashi Iizuka, Takeshi Obata, Masanori Ono, Yasunari Mizumoto, Chiaki Takahashi, Hiroshi Fujiwara, Takiko Daikoku

Journal: Commun Biol

PubMed ID: 38890503

Doi: 10.1038/s42003-024-06433-w

Products & Services: Molecular Biology Reagents

Molecular determinants of olfactory receptor activation: Comparative analysis of Olfr205 and Olfr740 family member responses to indole

Authors: Guangyao Li, Li Wang, Fangzhou Ye, Shengju Li, Hongmeng Yu

Journal: Arch Biochem Biophys

PubMed ID: 38880319

Doi: 10.1016/j.abb.2024.110061

Products & Services: Molecular Biology Reagents

Enhancing precision targeting of ovarian cancer tumor cells in vivo through extracellular vesicle engineering

Authors: Mona Alharbi, Andrew Lai, Nihar Godbole, Dominic Guanzon, Soumyalekshmi Nair, Felipe Zuñiga, Alexander Quinn, Mengliu Yang, Sherry Y Wu, Carlos Salomon

Journal: Int J Cancer

PubMed ID: 38848494

Doi: 10.1002/ijc.35055

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Selenium nanoparticles enhance mucosal immunity against Mycobacterium bovis infection

Authors: Xin Ge, Zhengmin Liang, Kui Li, Yuhui Dong, Yuanzhi Wang, Yiduo Liu, ZiYi Liu, Haoran Wang, Yue Nan, SiYan Chen, Lin Li, Yanbin Guo, Xiangmei Zhou

Journal: Int Immunopharmacol

PubMed ID: 38878484

Doi: 10.1016/j.intimp.2024.112384

Products & Services: Molecular Biology Reagents

Epitope-specific antibody fragments block aggregation of AGelD187N, an aberrant peptide in gelsolin amyloidosis

Authors: Laura Leimu, Patrik Holm, Anna Gąciarz, Oskar Haavisto, Stuart Prince, Ullamari Pesonen, Tuomas Huovinen, Urpo Lamminmäki

Journal: J Biol Chem

PubMed ID: 38944121

Doi: 10.1016/j.jbc.2024.107507

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Electrophysiological Impact of SARS-CoV-2 Envelope Protein in U251 Human Glioblastoma Cells: Possible Implications in Gliomagenesis?

Authors: Lorenzo Monarca, Francesco Ragonese, Andrea Biagini, Paola Sabbatini, Matteo Pacini, Alessandro Zucchi, Roberta Spaccapelo, Paola Ferrari, Andrea Nicolini, Bernard Fioretti

Journal: Int J Mol Sci

PubMed ID: 38928376

Doi: 10.3390/ijms25126669

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PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics

Authors: Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty

Journal: Nat Commun

PubMed ID: 38942756

Doi: 10.1038/s41467-024-49233-w

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Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity

Authors: Siddhi Omkar, Courtney Shrader, Joel R Hoskins, Jake T Kline, Megan M Mitchem, Luca Fornelli, Sue Wickner, Andrew W Truman

Journal: biorxiv

PubMed ID: 38915721

Doi: 10.1101/2024.06.13.598777

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miR-520e and its promoter region DNA methylation as potential biomarkers in atherosclerosis

Authors: Mimi Mu, Gao Liu, Xiaoyu Ding, Lijun Xue, Dandan Li, Yunhua Zhu, Nan Zhang, Jia Wu, Junjun Wang

Journal: Biochem Cell Biol

PubMed ID: 38917487

Doi: 10.1139/bcb-2023-0326

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Experimental inoculation of pigs with monkeypox virus results in productive infection and transmission to sentinels

Authors: Emily Mantlo, Jessie D Trujillo, Natasha N Gaudreault, Igor Morozov, Charles E Lewis, Franco Matias-Ferreyra, Chester McDowell, Dashzeveg Bold, Taeyong Kwon, Konner Cool, Velmurugan Balaraman, Daniel Madden, Bianca Artiaga, Jayme Souza-Neto, Jeffrey B Doty, Mariano Carossino, Udeni Balasuriya, William C Wilson, Nikolaus Osterrieder, Lisa Hensley, Juergen A Richt

Journal: Emerg Microbes Infect

PubMed ID: 38712637

Doi: 10.1080/22221751.2024.2352434

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Effect of TIMPs and Their Minimally Engineered Variants in Blocking Invasion and Migration of Brain Cancer Cells

Authors: Elham Taheri, Maryam Raeeszadeh-Sarmazdeh

Journal: biorxiv

PubMed ID: 38895489

Doi: 10.1101/2024.06.05.597644

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H3N2 canine influenza virus-like particle vaccine with great protection in beagle dogs

Authors: Fei-Fei Ge, Li-Pin Shen, De-Quan Yang, Xian-Cao Yang, Xin Li, Hai-Xiao Shen, Jian Wang, Shixin Huang

Journal: Microbiol Spectr

PubMed ID: 38874403

Doi: 10.1128/spectrum.00445-24

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Prokaryotic RNA N1-Methyladenosine Erasers Maintain tRNA m1A Modification Levels in

Authors: Marcus Foo, Luke R Frietze, Behnam Enghiad, Yujie Yuan, Christopher D Katanski, Huimin Zhao, Tao Pan

Journal: ACS Chem Biol

PubMed ID: 38912606

Doi: 10.1021/acschembio.4c00278

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Identification of a novel glycoside hydrolase family 8 xylanase from Deinococcus geothermalis and its application at low temperatures

Authors: Tingting Wang, Min Lin, Yongliang Yan, Shijie Jiang, Qilin Dai, Zhengfu Zhou, Jin Wang

Journal: Arch Microbiol

PubMed ID: 38884653

Doi: 10.1007/s00203-024-04055-8

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Transgenic Soybean for Production of Thermostable α-Amylase

Authors: Zhenyan Cao, Ye Jiang, Jiajie Li, Ting Zheng, Chaoyang Lin, Zhicheng Shen

Journal: Plants (Basel)

PubMed ID: 38891347

Doi: 10.3390/plants13111539

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Scaffold-enabled high-resolution cryo-EM structure determination of RNA

Authors: Daniel B Haack, Boris Rudolfs, Shouhong Jin, Kevin M Weeks, Navtej Toor

Journal: biorxiv

PubMed ID: 38915706

Doi: 10.1101/2024.06.10.598011

Products & Services: Molecular Biology Reagents

Functional characterization of a cystatin A from the bat Myotis davidii

Authors: Gabriel Cerqueira Alves Costa, Ricardo Jose Soares Torquato, Vinícius de Morais Gomes, Lívia Rosa-Fernandes, Giuseppe Palmisano, Aparecida Sadae Tanaka

Journal: Comp Biochem Physiol B Biochem Mol Biol

PubMed ID: 38936799

Doi: 10.1016/j.cbpb.2024.111003

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Assessing Predictive Value of SARS-CoV-2 Epitope-Specific CD8 T-Cell Response in Patients with Severe Symptoms

Authors: Cristina Martín-Martín, Estefanía Salgado Del Riego, Jose R Vidal Castiñeira, Maria Soledad Zapico-Gonzalez, Mercedes Rodríguez-Pérez, Viviana Corte-Iglesias, Maria Laura Saiz, Paula Diaz-Bulnes, Dolores Escudero, Beatriz Suárez-Alvarez, Carlos López-Larrea

Journal: Vaccines (Basel)

PubMed ID: 38932408

Doi: 10.3390/vaccines12060679

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Discovery, characterization, and comparative analysis of new UGT72 and UGT84 family glycosyltransferases

Authors: Tuo Li, Annika J E Borg, Leo Krammer, Hansjörg Weber, Rolf Breinbauer, Bernd Nidetzky

Journal: Commun Chem

PubMed ID: 38942997

Doi: 10.1038/s42004-024-01231-1

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DNA mismatch and damage patterns revealed by single-molecule sequencing

Authors: Mei Hong Liu, Benjamin M Costa, Emilia C Bianchini, Una Choi, Rachel C Bandler, Emilie Lassen, Marta Grońska-Pęski, Adam Schwing, Zachary R Murphy, Daniel Rosenkjær, Shany Picciotto, Vanessa Bianchi, Lucie Stengs, Melissa Edwards, Nuno Miguel Nunes, Caitlin A Loh, Tina K Truong, Randall E Brand, Tomi Pastinen, J Richard Wagner, Anne-Bine Skytte, Uri Tabori, Jonathan E Shoag, Gilad D Evrony

Journal: Nature

PubMed ID: 38867045

Doi: 10.1038/s41586-024-07532-8

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Production of norovirus-, rotavirus-, and enterovirus-like particles in insect cells is simplified by plasmid-based expression

Authors: Vili Lampinen, Stina Gröhn, Nina Lehmler, Minne Jartti, Vesa P Hytönen, Maren Schubert, Minna M Hankaniemi

Journal: Sci Rep

PubMed ID: 38937523

Doi: 10.1038/s41598-024-65316-6

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C-terminal Poly-histidine Tags Alter Escherichia coli Polyphosphate Kinase Activity and Susceptibility to Inhibition

Authors: Marvin Q Bowlin, Avery D Lieber, Abagail R Long, Michael J Gray

Journal: J Mol Biol

PubMed ID: 38866092

Doi: 10.1016/j.jmb.2024.168651

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IgE-Mediated Sensitization to Blo t 21 and Blo t 5 Is Associated With Asthma in the Tropics: A Case-Control Study

Authors: J Zakzuk, K Donado, E Mondol, V Marrugo, R Regino, J F López, K Hernandez, D Mercado, R Dennis, L Puerta, L Caraballo

Journal: J Investig Allergol Clin Immunol

PubMed ID: 38888580

Doi: 10.18176/jiaci.0892

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A soybean cyst nematode suppresses microbial plant symbionts using a lipochitooligosaccharide-hydrolysing enzyme

Authors: Wei Chen, Di Wang, Shaoyong Ke, Yangrong Cao, Wensheng Xiang, Xiaoli Guo, Qing Yang

Journal: Nat Microbiol

PubMed ID: 38886584

Doi: 10.1038/s41564-024-01727-5

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Arboviruses antagonize insect Toll antiviral immune signaling to facilitate the coexistence of viruses with their vectors

Authors: Dongsheng Jia, Guozhong Luo, Heran Guan, Tingting Yu, Xinyan Sun, Yu Du, Yiheng Wang, Hongyan Chen, Taiyun Wei

Journal: PLoS Pathog

PubMed ID: 38865374

Doi: 10.1371/journal.ppat.1012318

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Auxin resistant 2 and short hypocotyl 2 regulate cotton fiber initiation and elongation

Authors: Fei Jin, Liping Zhu, Liyong Hou, Hongbin Li, Ling Li, Guanghui Xiao

Journal: Plant Physiol

PubMed ID: 38527791

Doi: 10.1093/plphys/kiae183

Products & Services: Protein and Antibody Isolation

Interleukin-1 beta (IL-1β) as adjuvant enhances the immune effects of Aeromonas veronii inactivated vaccine in largemouth bass (Micropterus salmoides)

Authors: Ze-Sheng Zhang, Heng-Chu Ren, Xie Gu, Qian-Rong Liang, Hui Fei, Yu-Hong Yang, Shun Yang, Liang-Yin He, Li-Li Liu

Journal: Int J Biol Macromol

PubMed ID: 38876231

Doi: 10.1016/j.ijbiomac.2024.133135

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Development of Broad-Spectrum Nanobodies for the Therapy and Diagnosis of SARS-CoV-2 and Its Multiple Variants

Authors: Lei He, Qian Wu, Zhaoyong Zhang, Lingling Chen, Kuai Yu, Leibin Li, Qiong Jia, Yanqun Wang, Jianqiang Ni, Chuanbin Wang, Qi Li, Xinyan Zhai, Jincun Zhao, Yuliang Liu, Ruiwen Fan, Yi-Ping Li

Journal: Mol Pharm

PubMed ID: 38920116

Doi: 10.1021/acs.molpharmaceut.4c00165

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Synthetic Peptides Elicit Humoral Response against Porcine Reproductive and Respiratory Syndrome Virus in Swine

Authors: Francisco Perez-Duran, Fernando Calderon-Rico, Luis Enrique Franco-Correa, Alicia Gabriela Zamora-Aviles, Roberto Ortega-Flores, Daniel Durand-Herrera, Alejandro Bravo-Patiño, Ricarda Cortes-Vieyra, Ilane Hernandez-Morales, Rosa Elvira Nuñez-Anita

Journal: Vaccines (Basel)

PubMed ID: 38932381

Doi: 10.3390/vaccines12060652

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mRNA Vaccine for Alzheimer's Disease: Pilot Study

Authors: Armine Hovakimyan, Garri Chilingaryan, Olga King, Joia Kai Capocchi, Jean Paul Chadarevian, Hayk Davtyan, Roman Kniazev, Michael G Agadjanyan, Anahit Ghochikyan

Journal: Vaccines (Basel)

PubMed ID: 38932388

Doi: 10.3390/vaccines12060659

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Exploring a novel GH13_5 α-amylase from Jeotgalibacillus malaysiensis D5 for raw starch hydrolysis

Authors: Nurfatini Radzlin, Mohd Shukuri Mohamad Ali, Kian Mau Goh, Amira Suriaty Yaakop, Iffah Izzati Zakaria, Ummirul Mukminin Kahar

Journal: AMB Express

PubMed ID: 38874807

Doi: 10.1186/s13568-024-01722-3

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Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome

Authors: Boyang Zhao, Zhongzheng Cao, Yi Zheng, Phuong Nguyen, Alisa Bowen, Robert H Edwards, Robert M Stroud, Yi Zhou, Menno Van Lookeren Campagne, Fei Li

Journal: Nat Commun

PubMed ID: 38918376

Doi: 10.1038/s41467-024-49614-1

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Double promoter and tandem gene strategy for efficiently expressing recombinant FGF21

Authors: Longying Liu, Nuoyi Ning, Simeng Xu, Dongqing Chen, Luping Zhou, Zhimou Guo, Xinmiao Liang, Xianlong Ye

Journal: Microb Cell Fact

PubMed ID: 38867280

Doi: 10.1186/s12934-024-02447-5

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NbPTR1 confers resistance against Pseudomonas syringae pv actinidiae in kiwifruit

Authors: Shin-Mei Yeh, Minsoo Yoon, Sidney Scott, Abhishek Chatterjee, Lauren M Hemara, Ronan K Y Chen, Tianchi Wang, Kerry Templeton, Erik H A Rikkerink, Jay Jayaraman, Cyril Brendolise

Journal: Plant Cell Environ

PubMed ID: 38899426

Doi: 10.1111/pce.15002

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Development of a Ferritin Protein Nanoparticle Vaccine with PRRSV GP5 Protein

Authors: Xinjian Chang, Jun Ma, Yanrong Zhou, Shaobo Xiao, Xun Xiao, Liurong Fang

Journal: Viruses

PubMed ID: 38932282

Doi: 10.3390/v16060991

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Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2

Authors: J Wouter Beugelink, Els Sweep, Bert J C Janssen, Joost Snijder, Matti F Pronker

Journal: J Mol Biol

PubMed ID: 38852931

Doi: 10.1016/j.jmb.2024.168649

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Red2Flpe-SCON: a versatile, multicolor strategy for generating mosaic conditional knockout mice

Authors: Szu-Hsien Sam Wu, Somi Kim, Heetak Lee, Ji-Hyun Lee, So-Yeon Park, Réka Bakonyi, Isaree Teriyapirom, Natalia Hallay, Sandra Pilat-Carotta, Hans-Christian Theussl, Jihoon Kim, Joo-Hyeon Lee, Benjamin D Simons, Jong Kyoung Kim, Gabriele Colozza, Bon-Kyoung Koo

Journal: Nat Commun

PubMed ID: 38862535

Doi: 10.1038/s41467-024-49382-y

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Cost-Efficient Expression of Human Cardiac Myosin Heavy Chain in C2C12 Cells with a Non-Viral Transfection Reagent

Authors: Albin E Berg, Lok Priya Velayuthan, Alf Månsson, Marko Ušaj

Journal: Int J Mol Sci

PubMed ID: 38928453

Doi: 10.3390/ijms25126747

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CircVIRMA enhances cell malignant behavior by governing the miR-452-5p/CREBRF pathway in cervical cancer

Authors: Chengluo Hao, Jianjun Han, Kechao Xiang, Yun Wang, Xiangrui Chen, Chen Yang, Ailin Liang, Li Jia

Journal: Naunyn Schmiedebergs Arch Pharmacol

PubMed ID: 38850300

Doi: 10.1007/s00210-024-03159-8

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Circ_002033 Regulates Proliferation, Apoptosis, and Oxidative Damage of Bovine Mammary Epithelial Cells via the miR-199a-5p-MAP3K11 Axis in Heat Stress

Authors: Hanfang Zeng, Shujie Li, Haomiao Chang, Yunfei Zhai, Haihui Wang, Hantong Weng, Zhaoyu Han

Journal: J Agric Food Chem

PubMed ID: 38869955

Doi: 10.1021/acs.jafc.3c09835

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Immune responses and reinfection of SARS-CoV-2 Omicron variant in patients with lung cancer

Authors: Chen Chen, Xiaoyun Zhou, Xiaoxing Gao, Ruili Pan, Qi He, Xiaobei Guo, Siyuan Yu, Na Wang, Qian Zhao, Mengzhao Wang, Yan Xu, Xiaohong Han

Journal: Int J Cancer

PubMed ID: 38837354

Doi: 10.1002/ijc.35038

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New wheat straw fermentation feed: recombinant efficient degradation of lignocellulose and increase feed protein

Authors: Xihua Chen, Xiaoyu Liang, Na Shi, Lu He, Yi Ma, Daochen Zhu, Zhong Ni, Huayou Chen

Journal: Prep Biochem Biotechnol

PubMed ID: 38824495

Doi: 10.1080/10826068.2024.2353637

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Structure of the E. coli nucleoid-associated protein YejK reveals a novel DNA binding clamp

Authors: Maria A Schumacher, Rajiv R Singh, Raul Salinas

Journal: Nucleic Acids Res

PubMed ID: 38832628

Doi: 10.1093/nar/gkae459

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Mechanism of human PINK1 activation at the TOM complex in a reconstituted system

Authors: Olawale G Raimi, Hina Ojha, Kenneth Ehses, Verena Dederer, Sven M Lange, Cristian Polo Rivera, Tom D Deegan, Yinchen Chen, Melanie Wightman, Rachel Toth, Karim P M Labib, Sebastian Mathea, Neil Ranson, Rubén Fernández-Busnadiego, Miratul M K Muqit

Journal: SCIENCE ADVANCES

PubMed ID: 38848361

Doi: 10.1126/sciadv.adn7191

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TnpB homologues exapted from transposons are RNA-guided transcription factors

Authors: Tanner Wiegand, Florian T Hoffmann, Matt W G Walker, Stephen Tang, Egill Richard, Hoang C Le, Chance Meers, Samuel H Sternberg

Journal: Nature

PubMed ID: 38926585

Doi: 10.1038/s41586-024-07598-4

Understanding the Phase Behavior of a Multistimuli-Responsive Elastin-like Polymer: Insights from Dynamic Light Scattering Analysis

Authors: Peter C Swanson, Galen P Arnold, Carolyn E Curley, Savannah C Wakita, Jeffery D V Waters, Eva Rose M Balog

Journal: J Phys Chem B

PubMed ID: 38830627

Doi: 10.1021/acs.jpcb.4c00070

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Baculovirus surface display of a chimeric E-NS1 protein of YFV protects against YFV infection

Authors: Carla Tomatis, María Florencia Ferrer, Silvia Aquila, Pablo Daniel Thomas, Paula Nazarena Arrías, Leticia Ferrelli, Matías Pidre, Victor Romanowski, Eugenio Antonio Carrera Silva, Ricardo Martín Gómez

Journal: Vaccine

PubMed ID: 38852036

Doi: 10.1016/j.vaccine.2024.06.013

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Computer-Aided Semi-Rational Design to Enhance the Activity of l-Sorbosone Dehydrogenase from Gluconobacter oxidans WSH-004

Authors: Dong Li, Xinglong Wang, Lin Huo, Weizhu Zeng, Jianghua Li, Jingwen Zhou

Journal: J Agric Food Chem

PubMed ID: 38701424

Doi: 10.1021/acs.jafc.3c08365

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Engineered probiotics with sustained release of interleukin-2 for the treatment of inflammatory bowel disease after oral delivery

Authors: Maoyi Li, Nanhui Liu, Jiafei Zhu, Yumin Wu, Le Niu, Yi Liu, Linfu Chen, Boxiong Bai, Yu Miao, Yang Yang, Qian Chen

Journal: Biomaterials

PubMed ID: 38735180

Doi: doi.org/10.1016/j.biomaterials.2024.122584

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Cholesterol neutralized vemurafenib treatment by promoting melanoma stem‑like cells via its metabolite 27‑hydroxycholesterol

Authors: Xiaohong Wang, Feiliang Zhong, Tingting Chen, Hongbo Wang, Weifang Wang, Hongkai Jin, Chouyang Li, Xuan Guo, Ying Liu, Yu Zhang, Bo Li

Journal: Cell Mol Life Sci

PubMed ID: 38775844

Doi: 10.1007/s00018-024-05267-3

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Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry

Authors: Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J Gibbings, Laura Trinkle-Mulcahy, John W Copeland

Journal: Int J Mol Sci

PubMed ID: 38891874

Doi: 10.3390/ijms25115686

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ICG-labeled PD-L1-antagonistic affibody dimer for tumor imaging and enhancement of tumor photothermal-immunotherapy

Authors: Dianlong Jia, Shiqi Zhao, Huimin Liu, Xinyu Zhan, Zhongxia Zhou, Mingjia Lv, Xiufeng Tang, Wen Guo, Hui Li, Lilan Sun, Yidong Zhong, Baoqing Tian, Dandan Yuan, Xiaohui Tang, Qing Fan

Journal: Int J Biol Macromol

PubMed ID: 38704065

Doi: 10.1016/j.ijbiomac.2024.132058

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Ferritinophagy mediates adaptive resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer

Authors: Hui Wang, Qianfan Hu, Yuzhong Chen, Xing Huang, Yipeng Feng, Yuanjian Shi, Rutao Li, Xuewen Yin, Xuming Song, Yingkuan Liang, Te Zhang, Lin Xu, Gaochao Dong, Feng Jiang

Journal: Nat Commun

PubMed ID: 38760351

Doi: 10.1038/s41467-024-48433-8

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HIV-1 with gag processing defects activates cGAS sensing

Authors: Rebecca P Sumner, Henry Blest, Meiyin Lin, Carlos Maluquer de Motes, Greg J Towers

Journal: Retrovirology

PubMed ID: 38778414

Doi: 10.1186/s12977-024-00643-0

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Blue light-mediated gene expression as a promising strategy to reduce antibiotic resistance in Escherichia coli

Authors: Qingwei Jiang, Feng Geng, Juan Shen, Ping Zhu, Zhaoxin Lu, Fengxia Lu, Libang Zhou

Journal: Biotechnol J

PubMed ID: 38719589

Doi: 10.1002/biot.202400023

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Effect of Free Cysteine Residues to Serine Mutation on Cellodextrin Phosphorylase

Authors: Tomohiro Kuga, Naoki Sunagawa, Kiyohiko Igarashi

Journal: J Appl Glycosci (1999)

PubMed ID: 38863949

Doi: 10.5458/jag.jag.JAG-2023_0011

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A systematic analysis of affinity tags in the haloarchaeal expression system, for protein purification

Authors: Ram Karan, Dominik Renn, Thorsten Allers, Magnus Rueping

Journal: Front Microbiol

PubMed ID: 38873150

Doi: 10.3389/fmicb.2024.1403623

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CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent mice

Authors: Henriette Reventlow Frederiksen, Alexandra Glantz, Kåre Kryger Vøls, Søren Skov, Pernille Tveden-Nyborg, Kristine Freude, Ulrik Doehn

Journal: Front Genome Ed

PubMed ID: 38863835

Doi: 10.3389/fgeed.2024.1403395

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Understanding the Enzyme ()-Norcoclaurine Synthase Promiscuity to Aldehydes and Ketones

Authors: Brunno A Salvatti, Marcelo A Chagas, Phillipe O Fernandes, Yan F X Ladeira, Aline S Bozzi, Veronica S Valadares, Ana Paula Valente, Amanda S de Miranda, Willian R Rocha, Vinicius G Maltarollo, Adolfo H Moraes

Journal: J Chem Inf Model

PubMed ID: 38776464

Doi: 10.1021/acs.jcim.3c01773

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Therapeutic potentials of nonpeptidic V2R agonists for partial cNDI-causing V2R mutants

Authors: Ritsuki Kuramoto, Ryoji Kise, Mayu Kanno, Kouki Kawakami, Tatsuya Ikuta, Noriko Makita, Asuka Inoue

Journal: PLoS ONE

PubMed ID: 38748623

Doi: 10.1371/journal.pone.0303507

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Preamplification-free ultra-fast and ultra-sensitive point-of-care testing via LwaCas13a

Authors: Wanting Zeng, Wanping Chen, Yang Liu, Ting Zhang, Chao Zhai, Wenqiang Li, Longyu Wang, Cheng Zhang, Qili Zeng, Fei Wang, Lixin Ma

Journal: Biosens Bioelectron

PubMed ID: 38776799

Doi: 10.1016/j.bios.2024.116400

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The intrinsic substrate specificity of the human tyrosine kinome

Authors: Tomer M. Yaron-Barir, Brian A. Joughin, Emily M. Huntsman, Alexander Kerelsky, Daniel M. Cizin, Benjamin M. Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M. Orozco, Christina Schoenherr, Cari Sagum, Mark T. Bedford, R. Max Wynn, Shih-Chia Tso, David T. Chuang, Lei Li, Shawn S.-C. Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D. Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C. Frame, Peter V. Hornbeck, Lewis C. Cantley, Benjamin E. Turk, Michael B. Yaffe & Jared L. Johnson

Journal: Nature

PubMed ID: 38720073

Doi: 10.1038/s41586-024-07407-y

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Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin

Authors: Di Qu, Peng Ge, Laure Botella, Sae Woong Park, Ha-Na Lee, Natalie Thornton, James M. Bean, Inna V. Krieger, James C. Sacchettini, Sabine Ehrt, Courtney C. Aldrich & Dirk Schnappinger

Journal: Nat Commun

PubMed ID: 38755122

Doi: 10.1038/s41467-024-48448-1.

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Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody binding

Authors: Hongjun Bai, Eric Lewitus, Yifan Li, Paul V. Thomas, Michelle Zemil, Mélanie Merbah, Caroline E. Peterson, Thujitha Thuraisamy, Phyllis A. Rees, Agnes Hajduczki, Vincent Dussupt, Bonnie Slike, Letzibeth Mendez-Rivera, Annika Schmid, Erin Kavusak, Mekhala Rao, Gabriel Smith, Jessica Frey, Alicea Sims, Lindsay Wieczorek, Victoria Polonis, Shelly J. Krebs, Julie A. Ake, Sandhya Vasan, Diane L. Bolton, M. Gordon Joyce, Samantha Townsley & Morgane Rolland

Journal: Nat Commun

PubMed ID: 38724518

Doi: 10.1038/s41467-024-48139-x

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Structural basis for double-stranded RNA recognition by SID1

Authors: Runhao Wang, Ye Cong, Dandan Qian, Chuangye Yan, Deshun Gong

Journal: Nucleic Acids Res

PubMed ID: 38742627

Doi: 10.1093/nar/gkae395

Enhanced detection of ligand-PPARγ binding based on surface plasmon resonance through complexation with SRC1- or NCOR2-related polypeptide

Authors: Yiting Wang , Mingzhu Luo , Luyang Che , Qixin Wu , Jingzhe Li , Yanyan Ma , Jingyi Wang , Changzhen Liu

Journal: International Journal of Biological Macromolecules

PubMed ID: 38670200

Doi: 10.1016/j.ijbiomac.2024.131865

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A Tag-Free Platform for Synthesis and Screening of Cyclic Peptide Libraries

Authors: Angele Bruce , Victor Adebomi , Patrick Czabala , Jonathan Palmer , William M McFadden , Zachary C Lorson , Ryan L Slack , Gaurav Bhardwaj , Stefan G Sarafianos , Monika Raj

Journal: Angew Chem Int Ed Engl

PubMed ID: 38529717

Doi: 10.1002/anie.202320045

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Micro-and nano-plastics induce kidney damage and suppression of innate immune function in zebrafish (Danio rerio) larvae

Authors: Hui Yang, Jian Ju, Yuting Wang, Zhu Zhu, Wenyan Lu, Yingying Zhang

Journal: Sci Total Environ

PubMed ID: 38703841

Doi: 10.1016/j.scitotenv.2024.172952

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Intranasal vaccination with an NDV-vectored SARS-CoV-2 vaccine protects against Delta and Omicron challenges

Authors: Bryce M Warner, Jacob G E Yates, Robert Vendramelli, Thang Truong, Courtney Meilleur, Lily Chan, Alexander Leacy, Phuc H Pham, Yanlong Pei, Leonardo Susta, Sarah K Wootton, Darwyn Kobasa

Journal: npj Vaccines

PubMed ID: 38782986

Doi: 10.1038/s41541-024-00870-8

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Development and characterization of an antibody that recognizes influenza virus N1 neuraminidases

Authors: Nan Chen, Renxi Wang, Wanlu Zhu, Xiangjun Hao, Jing Wang, Guojiang Chen, ChunXia Qiao, Xinying Li, Chenghua Liu, Beifen Shen, Jiannan Feng, Lihui Chai, Zuyin Yu, He Xiao

Journal: PLoS ONE

PubMed ID: 38723016

Doi: 10.1371/journal.pone.0302865

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Design, Construction, and Validation of a Yeast-Displayed Chemically Expanded Antibody Library

Authors: Arlinda Rezhdo, Rebecca L Hershman, James A Van Deventer

Journal: biorxiv

PubMed ID: 38853888

Doi: 10.1101/2024.05.29.596443

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Temperature-dependent iron motion in extremophile rubredoxins - no need for 'corresponding states'

Authors: Francis E Jenney, Hongxin Wang, Simon J George, Jin Xiong, Yisong Guo, Leland B Gee, Juan José Marizcurrena, Susana Castro-Sowinski, Anna Staskiewicz, Yoshitaka Yoda, Michael Y Hu, Kenji Tamasaku, Nobumoto Nagasawa, Lei Li, Hiroaki Matsuura, Tzanko Doukov, Stephen P Cramer

Journal: Sci Rep

PubMed ID: 38806591

Doi: 10.1038/s41598-024-62261-2

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Tetrahydroxy stilbene glucoside rejuvenates aging hematopoietic stem cells with predilection for lymphoid differentiation via AMPK and Tet2

Authors: Dan Gao, Wei-Wei Yi, Bo Liu, Cong-En Zhang, Cui-Cui Yang, Li Zeng, Lin Li, Guangbin Luo, Lan Zhang, Zhen-Yu Ju, Jia-Bo Wang

Journal: J Adv Res

PubMed ID: 38704089

Doi: 10.1016/j.jare.2024.04.027

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CRTAC1 identified as a promising diagnosis and prognostic biomarker in lung adenocarcinoma

Authors: Lin Tan, Han Zhang, Yun Ding, Yangyun Huang, Daqiang Sun

Journal: Sci Rep

PubMed ID: 38755183

Doi: 10.1038/s41598-024-61804-x

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Antitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4

Authors: Jianyao Zeng, Yuan Fang, Zixuan Zhang, Zhenzhen Lv, Xiaodie Wang, Qian Huang, Zhidan Tian, Jiaguo Li, Wenfeng Xu, Weimin Zhu, Jing Yu, Tao Liu, Qijun Qian

Journal: Oncogene

PubMed ID: 38806619

Doi: 10.1038/s41388-024-03066-5

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A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy

Authors: Dan A Tudorica, Bishal Basak, Alexia S Puerta Cordova, Grace Khuu, Kevin Rose, Michael Lazarou, Erika L F Holzbaur, James H Hurley

Journal: J Cell Biol

PubMed ID: 38728007

Doi: 10.1083/jcb.202309015

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Post-transcriptional regulation of the T-box gene midline via the 3'UTR in Drosophila is complex and cell and tissue-dependent

Authors: Kalpana Makhijani, Jordan Mar, Ivana Gaziova, Krishna Moorthi Bhat

Journal: Genetics

PubMed ID: 38805187

Doi: 10.1093/genetics/iyae087

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Stacked mutations in wheat homologues of rice SEMI-DWARF1 confer a novel semi-dwarf phenotype

Authors: Barbora Ndreca, Alison Huttly, Sajida Bibi, Carlos Bayon, George Lund, Joshua Ham, Rocío Alarcón-Reverte, John Addy, Danuše Tarkowská, Stephen Pearce, Peter Hedden, Stephen G Thomas, Andrew L Phillips

Journal: BMC Plant Biol

PubMed ID: 38724935

Doi: 10.1186/s12870-024-05098-1

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Acts as a Positive Regulator of Secondary Cell Wall Synthesis in Sudan Grass ( S)

Authors: Yanzhong Huang, Juanzi Wu, Jianyu Lin, Zhiwei Liu, Zhengfeng Mao, Chen Qian, Xiaoxian Zhong

Journal: Plants (Basel)

PubMed ID: 38794423

Doi: 10.3390/plants13101352

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Accuracy of Anti-SARS-CoV-2 Antibody in Comparison with Surrogate Viral Neutralization Test in Persons Living with HIV, Systemic Lupus Erythematosus, and Chronic Kidney Disease

Authors: Marita Restie Tiara, Chrisan Bimo Prayuda, Tara Titian Maulidya, Hofiya Djauhari, Dadang Suhendar, Rudi Wisaksana, Laniyati Hamijoyo, Rudi Supriyadi, Agnes Rengga Indrati, Bachti Alisjahbana

Journal: Vaccines (Basel)

PubMed ID: 38793809

Doi: 10.3390/vaccines12050558

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Identification and characterization of calcium binding protein, spermatid-associated 1 (CABS1)# in selected human tissues and fluids

Authors: Eduardo Reyes-Serratos, Joy Ramielle L Santos, Lakshmi Puttagunta, Stephen J Lewis, Mechiko Watanabe, Aron Gonshor, Robert Buck, A Dean Befus, Marcelo Marcet-Palacios

Journal: PLoS ONE

PubMed ID: 38753592

Doi: 10.1371/journal.pone.0301855

Development and validation of an HILIC/MS/MS method for determination of nusinersen in rabbit plasma

Authors: Xiao Zhang, Chunjie Sha, Wei Zhang, Fengjuan Zhao, Mingli Zhu, Guangyi Leng, Wanhui Liu

Journal: Heliyon

PubMed ID: 38799737

Doi: 10.1016/j.heliyon.2024.e31213

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Design of antiviral AGO2-dependent short hairpin RNAs

Authors: Yuanyuan Bie, Jieling Zhang, Jiyao Chen, Yumin Zhang, Muhan Huang, Leike Zhang, Xi Zhou, Yang Qiu

Journal: Virol Sin

PubMed ID: 38734183

Doi: 10.1016/j.virs.2024.05.001

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4-Octyl Itaconate Attenuates Neuroinflammation in Experimental Autoimmune Encephalomyelitis Via Regulating Microglia

Authors: Ning Zhao, Ming Yi, Lin-Jie Zhang, Qiu-Xia Zhang, Li Yang

Journal: Inflammation

PubMed ID: 38761250

Doi: 10.1007/s10753-024-02050-1

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Effect of three oral pathogens on the TMA-TMAO metabolic pathway

Authors: Xixuan Wang, Liyuan Chen, Ye Teng, Weige Xie, Lingyan Huang, Juan Wu, Hongwei Wang, Sijing Xie

Journal: Front Cell Infect Microbiol

PubMed ID: 38836053

Doi: 10.3389/fcimb.2024.1413787

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Kanglexin counters vascular smooth muscle cell dedifferentiation and associated arteriosclerosis through inhibiting PDGFR

Authors: Shuang Yang, Yixiu Zhao, Shifeng Cao, Xinxin Liu, Min Feng, Yi Chen, Chunyue Ma, Tingting Zhan, Qi Zhang, Honglin Jia, Yu Zhao, Ming Tong, Yuanyuan Yu, Xue Liu, Baofeng Yang, Yan Zhang

Journal: Phytomedicine

PubMed ID: 38759316

Doi: 10.1016/j.phymed.2024.155704

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TOP CAR with TMIGD2 as a safe and effective costimulatory domain in CAR cells treating human solid tumors

Authors: Christopher D Nishimura, Devin Corrigan, Xiang Yu Zheng, Phillip M Galbo, Shan Wang, Yao Liu, Yao Wei, Linna Suo, Wei Cui, Nadia Mercado, Deyou Zheng, Cheng Cheng Zhang, Xingxing Zang

Journal: Sci Adv

PubMed ID: 38718110

Doi: 10.1126/sciadv.adk1857

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Glycan Profile and Sequence Variants of Certified Ricin Reference Material and Other Ricin Samples Yield Unique Molecular Signature Features

Authors: Roland Josuran, Andreas Wenger, Christian Müller, Bettina Kampa, Sylvia Worbs, Brigitte G Dorner, Sabina Gerber

Journal: Toxins (Basel)

PubMed ID: 38922138

Doi: 10.3390/toxins16060243

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Detection of calcitonin gene-related peptide based on increased antigen-driven interaction with antibody variable regions

Authors: Yueqing Cheng, Yujie Gao, Shengshuo Zhang, Yujie Zou, Guangwei Zhao, Liyuan Zheng, Binghui Hou, Mei Li, Jinhua Dong

Journal: Front Bioeng Biotechnol

PubMed ID: 38882635

Doi: 10.3389/fbioe.2024.1395330

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Construction of a grpE-based plasmid addiction system in Escherichia coli and its application in phloroglucinol biosynthesis

Authors: Ji-Ming Wang, Yu-Jin Cao, Xiao Men, Hai-Bo Zhang

Journal: J Appl Microbiol

PubMed ID: 38724452

Doi: 10.1093/jambio/lxae116

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N-MYC impairs innate immune signaling in high-grade serous ovarian carcinoma

Authors: Alex Miranda, Swetansu Pattnaik, Phineas T Hamilton, Monica Alvaro Fuss, Shreena Kalaria, Céline M Laumont, Julian Smazynski, Monica Mesa, Allyson Banville, Xinpei Jiang, Russell Jenkins, Israel Cañadas, Brad H Nelson

Journal: Sci Adv

PubMed ID: 38748789

Doi: 10.1126/sciadv.adj5428

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Structure of a human monoclonal antibody in complex with Outer surface protein C (OspC) of the Lyme disease spirochete,

Authors: Michael J Rudolph, Yang Chen, Clint Vorauer, David J Vance, Carol Lyn Piazza, Graham G Willsey, Kathleen McCarthy, Beatrice Muriuki, Lisa A Cavacini, Miklos Guttman, Nicholas J Mantis

Journal: biorxiv

PubMed ID: 38746285

Doi: 10.1101/2024.04.29.591597

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Development of novel monoclonal antibodies for blocking NF-κB activation induced by CD2v protein in African swine fever virus

Authors: Rongrong Fan, Zeliang Wei, Mengmeng Zhang, Shanshan Jia, Zhiyang Jiang, Yao Wang, Junyu Cai, Guojiang Chen, He Xiao, Yinxiang Wei, Yanchun Shi, Jiannan Feng, Beifen Shen, Yuanqiang Zheng, Yaojiang Huang, Jing Wang

Journal: Front Immunol

PubMed ID: 38846950

Doi: 10.3389/fimmu.2024.1352404

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Mapping adipocyte interactome networks by HaloTag-enrichment-mass spectrometry

Authors: Junshi Yazaki, Takashi Yamanashi, Shino Nemoto, Atsuo Kobayashi, Yong-Woon Han, Tomoko Hasegawa, Akira Iwase, Masaki Ishikawa, Ryo Konno, Koshi Imami, Yusuke Kawashima, Jun Seita

Journal: Biol Methods Protoc

PubMed ID: 38884001

Doi: 10.1093/biomethods/bpae039

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HIV BG505 SOSIP664 trimer with 3M-052-AF/alum induces human autologous tier-2 neutralizing antibodies

Authors: William O Hahn, K Rachael Parks, Mingchao Shen, Gabriel Ozorowski, Holly Janes, Lamar Ballweber-Fleming, Amanda S Woodward Davis, Chris Duplessis, Mark Tomai, Antu K Dey, Zachary K Sagawa, Stephen C De Rosa, Aaron Seese, Latha Kallur Siddaramaiah, Leonidas Stamatatos, Wen-Hsin Lee, Leigh M Sewall, Dalton Karlinsey, Hannah L Turner, Vanessa Rubin, Sarah Furth, Kellie MacPhee, Michael Duff, Lawrence Corey, Michael C Keefer, Srilatha Edupuganti, Ian Frank, Janine Maenza, Lindsey R Baden, Ollivier Hyrien, Rogier W Sanders, John P Moore, Andrew B Ward, Georgia D Tomaras, David C Montefiori, Nadine Rouphael, M Juliana McElrath

Journal: medrxiv

PubMed ID: 38766048

Doi: 10.1101/2024.05.08.24306957

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