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Cooperative nutrient scavenging is an evolutionary advantage in cancer

Authors: Gizem Guzelsoy, Setiembre D Elorza, Manon Ros, Logan T Schachtner, Makiko Hayashi, Spencer Hobson-Gutierrez, Parker Rundstrom, Julia S Brunner, Ray Pillai, William E Walkowicz, Lydia W S Finley, Maxime Deforet, Thales Papagiannakopoulos, Carlos Carmona-Fontaine

Journal: Nature

PubMed ID: 39972131

Doi: 10.1038/s41586-025-08588-w

Products & Services: Peptide Synthesis

Conserved immunomodulation and variation in host association by Xanthomonadales commensals in Arabidopsis root microbiota

Authors: Jana Ordon、Elke Logemann、Louis-Philippe Maier、Tak Lee、Eik Dahms、Anniek Oosterwijk、Jose Flores-Uribe、Shingo Miyauchi、Lucas Paoli、Sara Christina Stolze、Hirofumi Nakagami、Georg Felix、Ruben Garrido-Oter、Ka-Wai Ma 和 Paul Schulze-Lefert

Journal: Nat Plants

PubMed ID: 39972185

Doi: 10.1038/s41477-025-01918-w

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Structural basis of ssDNA-guided NADase activation of prokaryotic SPARTA system

Authors: Rong Hu, Chenmin Guo, Xiaotian Liu, Yuanyi Lin, Zixin Yang, Zhixin Li, Ye Yang, Erman Ma, Yiyi Li, Jiyun Chen, Liang Liu

Journal: Nucleic Acids Res

PubMed ID: 39997222

Doi: 10.1093/nar/gkaf110

Products & Services: Gene Synthesis

Reversible ubiquitination conferred by domain shuffling controls paired NLR immune receptor complex homeostasis in plant immunity

Authors: Zhiyi Chen, Jianhua Huang, Jianyu Li, Frank L. H. Menke, Jonathan D. G. Jones & Hailong Guo

Journal: Nature Communications

Doi: 10.1038/s41467-025-57231-9

Products & Services: Protein and Antibody Isolation

ABC transporter activity is affected by the size of lipid nanodiscs

Authors: Annabella Nouel Barreto, Luis G Cuello, Maria E Zoghbi

Journal: FEBS Letters

PubMed ID: 39748569

Doi: 10.1002/1873-3468.15096

Products & Services: Gene Synthesis Custom Vector Construction

Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies

Authors: Yan-Ruide Li, Ying Fang, Siyue Niu, Yichen Zhu, Yuning Chen, Zibai Lyu, Enbo Zhu, Yanxin Tian, Jie Huang, Valerie Rezek, Scott Kitchen, Tzung Hsiai, Jin J Zhou, Pin Wang, Wanxing Chai-Ho, Sunmin Park, Christopher S Seet, Caspian Oliai, Lili Yang

Journal: Nature Communications

PubMed ID: 39893165

Doi: 10.1038/s41467-025-56270-6

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Massively parallel variant-to-function mapping determines functional regulatory variants of non-small cell lung cancer

Authors: Congcong Chen, Yang Li, Yayun Gu, Qiqi Zhai, Songwei Guo, Jun Xiang, Yuan Xie, Mingxing An, Chenmeijie Li, Na Qin, Yanan Shi, Liu Yang, Jun Zhou, Xianfeng Xu, Ziye Xu, Kai Wang, Meng Zhu, Yue Jiang, Yuanlin He, Jing Xu, Rong Yin, Liang Chen, Lin Xu, Juncheng Dai, Guangfu Jin, Zhibin Hu, Cheng Wang, Hongxia Ma, Hongbing Shen

Journal: Nature Communications

PubMed ID: 39910069

Doi: 10.1038/s41467-025-56725-w

Products & Services: Gene Synthesis

Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses

Authors: Cheng-Bao Ma, Chen Liu, Young-Jun Park, Jingjing Tang, Jing Chen, Qing Xiong, Jimin Lee, Cameron Stewart, Daniel Asarnow, Jack Brown, M Alejandra Tortorici, Xiao Yang, Ye-Hui Sun, Yuan-Mei Chen, Xiao Yu, Jun-Yu Si, Peng Liu, Fei Tong, Mei-Ling Huang, Jing Li, Zheng-Li Shi, Zengqin Deng, David Veesler, Huan Yan

Journal: Cell

PubMed ID: 39922191

Doi: 10.1016/j.cell.2024.12.031

Products & Services: Codon Optimization

Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses

Authors: Young-Jun Park, Chen Liu, Jimin Lee, Jack T Brown, Cheng-Bao Ma, Peng Liu, Risako Gen, Qing Xiong, Samantha K Zepeda, Cameron Stewart, Amin Addetia, Caroline J Craig, M Alejandra Tortorici, Abeer N Alshukairi, Tyler N Starr, Huan Yan, David Veesler

Journal: Cell

PubMed ID: 39922192

Doi: 10.1016/j.cell.2024.12.032

Products & Services: Codon Optimization

Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling

Authors: Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Persechino, Sripriya Murthy, Cesare Orlandi, Christian D Sadik, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, Nina Wettschureck

Journal: Nature Communications

PubMed ID: 39920161

Doi: 10.1038/s41467-025-56713-0

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Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350

Authors: M Gordon Joyce, Wei Bu, Wei-Hung Chen, Rebecca A Gillespie, Sarah F Andrews, Adam K Wheatley, Yaroslav Tsybovsky, Jaime L Jensen, Tyler Stephens, Madhu Prabhakaran, Brian E Fisher, Sandeep R Narpala, Meghna Bagchi, Adrian B McDermott, Gary J Nabel, Peter D Kwong, John R Mascola, Jeffrey I Cohen, Masaru Kanekiyo

Journal: Immunity

PubMed ID: 39909035

Doi: 10.1016/j.immuni.2025.01.010

Products & Services: Recombinant Antibody Expression

Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates

Authors: Prakash Jadhav, Xueying Liang, Ahmadullah Ansari, Bin Tan, Haozhou Tan, Kan Li, Xiang Chi, Alexandra Ford, Francesc Xavier Ruiz, Eddy Arnold, Xufang Deng, Jun Wang

Journal: Nature Communications

PubMed ID: 39948104

Doi: 10.1038/s41467-025-56902-x

Products & Services: Codon Optimization

Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ

Authors: Bing Wang, Nelly Said, Tarek Hilal, Mark Finazzo, Markus C Wahl, Irina Artsimovitch

Journal: Nature Communications

PubMed ID: 39952913

Doi: 10.1038/s41467-025-56824-8

Products & Services: Protein Electrophoresis and Western

The CXCL8/MAPK/hnRNP-K axis enables susceptibility to infection by EV-D68, rhinovirus, and influenza virus in vitro

Authors: Qingran Yang, Haoran Guo, Huili Li, Zhaoxue Li, Fushun Ni, Zhongmei Wen, Kai Liu, Huihui Kong, Wei Wei

Journal: Nature Communications

PubMed ID: 39962077

Doi: 10.1038/s41467-025-57094-0

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Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells

Authors: Mélanie Uguen, Devan J Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M Szewczyk, Ka Yang, Yani Zhao, Michael A Stashko, Jacqueline L Norris-Drouin, Jarod M Waybright, Serap Beldar, Justin M Rectenwald, Angie L Mordant, Thomas S Webb, Laura E Herring, Cheryl H Arrowsmith, Suzanne Ackloo, Steven P Gygi, Robert K McGinty, Dalia Barsyte-Lovejoy, Pengda Liu, Levon Halabelian, Lindsey I James, Kenneth H Pearce, Stephen V Frye

Journal: Nature Communications

PubMed ID: 39994194

Doi: 10.1038/s41467-025-57005-3

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Dual functional POGases from bacteria encompassing broader O-glycanase and adhesin activities

Authors: Linjiao Zhou, Uriel Ortega-Rodriguez, Matthew J Flores, Yasuyuki Matsumoto, John Q Bettinger, Wells W Wu, Yaqin Zhang, Su-Ryun Kim, Thomas G Biel, Jordan D Pritts, Rong-Fong Shen, V Ashutosh Rao, Tongzhong Ju.

Journal: Nature Communications

PubMed ID: 40000644

Doi: 10.1038/s41467-025-57143-8

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The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

Authors: Shahid Banday, Alok K Mishra, Romana Rashid, Tianyi Ye, Amjad Ali, Junhui Li, Jason T Yustein, Michelle A Kelliher, Lihua Julie Zhu, Sara K Deibler, Sunil K Malonia, Michael R Green

Journal: Nature Communications

PubMed ID: 39894896

Doi: 10.1038/s41467-025-56632-0

Products & Services: Plasmid DNA Preparation

Structural basis of SIRT7 nucleosome engagement and substrate specificity

Authors: Carlos Moreno-Yruela, Babatunde E Ekundayo, Polina N Foteva, Dongchun Ni, Esther Calvino-Sanles, Henning Stahlberg, Beat Fierz

Journal: Nature Communications

PubMed ID: 39900593

Doi: 10.1038/s41467-025-56529-y

Products & Services: Protein Electrophoresis and Western

Synthetic lethality of mRNA quality control complexes in cancer

Authors: Vivian Prindle, Adam E Richardson, Kimberly R Sher, Sarah Kongpachith, Kaitlin Kentala, Sakina Petiwala, Dong Cheng, Deborah Widomski, Phuong Le, Maricel Torrent, Anlu Chen, Stephen Walker, Marianne B Palczewski, Diya Mitra, Vlasios Manaves, Xu Shi, Charles Lu, Stephanie Sandoval, Zoltan Dezso, F Gregory Buchanan, Daniel Verduzco, Brian Bierie, Jonathan A Meulbroek, William N Pappano, Joshua P Plotnik

Journal: Nature

PubMed ID: 39910291

Doi: 10.1038/s41586-024-08398-6

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Antibody prophylaxis may mask subclinical SIV infections in macaques

Authors: Christopher A Gonelli, Hannah A D King, SungYoul Ko, Christine M Fennessey, Nami Iwamoto, Rosemarie D Mason, Ashley Heimann, Dillon R Flebbe, John-Paul Todd, Kathryn E Foulds, Brandon F Keele, Jeffrey D Lifson, Richard A Koup, Mario Roederer.

Journal: Nature

PubMed ID: 39910294

Doi: 10.1038/s41586-024-08500-y

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Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I

Authors: Bryan Neumann, Stephen McCarthy, Shane Gonen

Journal: Nature Communications

PubMed ID: 39920100

Doi: 10.1038/s41467-024-55764-z

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Co-translational protein aggregation and ribosome stalling as a broad-spectrum antibacterial mechanism

Authors: Laleh Khodaparast, Ladan Khodaparast, Ramon Duran-Romaña, Guiqin Wu, Bert Houben, Wouter Duverger, Matthias De Vleeschouwer, Katerina Konstantoulea, Fleur Nysen, Thomas Schalck, Daniel J Curwen, Lisandra L Martin, Sebastien Carpentier, Bernard Scorneaux, Jan Michiels, Joost Schymkowitz, Frederic Rousseau

Journal: Nature Communications

PubMed ID: 39939597

Doi: 10.1038/s41467-025-56873-z

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Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers

Authors: Kai Li, Xuan Yu, Yanteng Xu, Haixia Wang, Zheng Liu, Chong Wu, Xing Luo, Jiancheng Xu, Youqiang Fang, Enguo Ju, Shixian Lv, Hon Fai Chan, Yeh-Hsing Lao, Weiling He, Yu Tao, Mingqiang Li

Journal: Nature Communications

PubMed ID: 39952937

Doi: 10.1038/s41467-025-56407-7

Products & Services: Recombinant Proteins

Proteasomes accumulate in the plant apoplast where they participate in microbe-associated molecular pattern (MAMP)-triggered pathogen defense

Authors: Hana Zand Karimi, Kuo-En Chen, Marilee Karinshak, Xilin Gu, Jason K Sello, Richard D Vierstra

Journal: Nature Communications

PubMed ID: 39952938

Doi: 10.1038/s41467-025-56594-3

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GMRSP encoded by lncRNA H19 regulates metabolic reprogramming and alleviates aortic dissection

Authors: Jizhong Wang, Jitao Liu, Fan Yang, Yinghao Sun, Jiaohua Chen, Jie Liu, Tucheng Sun, Ruixin Fan, Fang Pei, Songyuan Luo, Jie Li, Jianfang Luo

Journal: Nature Communications

PubMed ID: 39966416

Doi: 10.1038/s41467-025-57011-5

Alternatively spliced NFKB1 transcripts enriched in Andean Aymara modulate inflammation, HIF and hemoglobin

Authors: Jihyun Song, Seonggyun Han, Ricardo Amaru, Lucie Lanikova, Teddy Quispe, Dongwook Kim, Jacob E Crawford, Soo Jin Kim, Younghee Lee, Josef T Prchal

Journal: Nature Communications

PubMed ID: 39971917

Doi: 10.1038/s41467-025-56848-0

Products & Services: Protein Electrophoresis and Western

Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration.

Authors: Qiyu Tang, Keyi Tang, Greg R Markby, Maciej Parys, Kanchan Phadwal, Vicky E MacRae, Brendan M Corcoran

Journal: Autophagy

PubMed ID: 39988732

Doi: 10.1080/15548627.2025.2469315

Products & Services: CRISPR Plasmids

Pan-Variant SARS-CoV-2 Vaccines Induce Protective Immunity by Targeting Conserved Epitopes

Authors: Masaud Shah, Sung Ung Moon, Ji-Yon Shin, Ji-Hye Choi, Doyoon Kim, Hyun Goo Woo

Journal: Advanced Science

PubMed ID: 40014015

Doi: 10.1002/advs.202409919

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Sequence Context-Agnostic TadA-Derived Cytosine Base Editors for Genome-Wide Editing in Zebrafish

Authors: Shaohui Zheng 1 2, Yang Liu 1 2, Xinxin Xia 1 2, Jiawang Xiao 1 2, Hui Ma 3, Xuanyao Yuan 1 2, Yan Zhang 1 2, Zixi Chen 1 2, Guangcong Peng 1 2, Wenyuan Li 4, Ji-Feng Fei 3 5 6, Yanmei Liu

Journal: Advanced Science

PubMed ID: 39960330

Doi: 10.1002/advs.202411478

Distinct immunogenicity outcomes of DNA vaccines encoding malaria transmission-blocking vaccine target antigens Pfs230D1M and Pvs230D1

Authors: Yi Cao , Maisa da Silva Araujo , Cynthia G Lorang , Najara Akira Costa Dos Santos , Abhai Tripathi , Joseph Vinetz , Nirbhay Kumar

Journal: Vaccine

PubMed ID: 39787798

Doi: 10.1016/j.vaccine.2024.126696

Products & Services: Gene Synthesis Plasmid DNA Preparation

Establishment of an indirect ELISA method for detecting bovine coronavirus antibodies based on N protein

Authors: Qiang Liu , Xiaoxia Niu , Lingling Jiang , Gang Zhang , Pu Wang , Sinong Zhang , Weifeng Gao , Huichen Guo, Yujiong Wang and Yong Li

Journal: Frontiers in Veterinary Science

Doi: 10.3389/fvets.2025.1530870

Products & Services: Plasmid DNA Preparation

In vitro reconstitution of meiotic DNA double-strand-break formation

Authors: Xinzhe Tang , Zetao Hu , Jian Ding , Meixia Wu , Pin Guan , Yawei Song , Yue Yin , Wei Wu , Jinbiao Ma , Ying Huang , Ming-Han Tong

Journal: Nature

PubMed ID: 39972125

Doi: doi.org/10.1038/s41586-024-08551-1

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Identifying Exifone as a Dual-Target Agent Targeting Both SARS-CoV-2 3CL Protease and the ACE2/S-RBD Interaction Among Clinical Polyphenolic Compounds

Authors: Jiani Lu、Yan Tang、Hongtao Li、Xixiang Chen、Pengcheng Qin、Jianrong Xu、Weihua Li 和 Lili Chen

Journal: International Journal of Molecular Sciences

Doi: doi.org/10.3390/ijms26052243

Products & Services: Plasmid DNA Preparation

Polyamine-Depleting Hydrogen-Bond Organic Frameworks Unleash Dendritic Cell and T Cell Vigor for Targeted CRISPR/Cas-Assisted Cancer Immunotherapy

Authors: Yongchun Pan, Fei Zeng, Xiaowei Luan, Guanzhong He, Shurong Qin, Qianglan Lu, Bangshun He, Xin Han, Yujun Song

Journal: Adv Mater

PubMed ID: 39972681

Doi: 10.1002/adma.202411886

Products & Services: Recombinant Proteins

A truncated pre-F protein mRNA vaccine elicits an enhanced immune response and protection against respiratory syncytial virus

Authors: Min Lin, Yifan Yin, Xiaomeng Zhao, Chen Wang, Xueqing Zhu, Letao Zhan, Li Chen, Siling Wang, Xue Lin, Jun Zhang, Ningshao Xia, Zizheng Zheng

Journal: Nat Commun

PubMed ID: 39910047

Doi: 10.1038/s41467-025-56302-1

Products & Services: Protein and Antibody Isolation

The short conserved region-2 of LARP4 interacts with ribosome-associated RACK1 and promotes translation

Authors: Amitabh Ranjan, Sandy Mattijssen, Nithin Charlly, Isabel Cruz Gallardo, Leah F Pitman, Jennifer C Coleman, Maria R Conte, Richard J Maraia。

Journal: Nucleic Acids Res

PubMed ID: 39898547

Doi: 10.1093/nar/gkaf053

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Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane

Authors: Kathryn M Hastie, Zhe Li Salie, Zunlong Ke, Peter J Halfmann, Lisa Evans DeWald, Sara McArdle, Ariadna Grinyó, Edgar Davidson, Sharon L Schendel, Chitra Hariharan, Michael J Norris, Xiaoying Yu, Chakravarthy Chennareddy, Xiaoli Xiong, Megan Heinrich, Michael R Holbrook, Benjamin Doranz, Ian Crozier, Yoshihiro Kawaoka, Luis M Branco, Jens H Kuhn, John A G Briggs, Gabriella Worwa, Carl W Davis, Rafi Ahmed, Erica Ollmann Saphire

Journal: Nature Communications

PubMed ID: 39900911

Doi: 10.1038/s41467-025-56452-2

Products & Services: Protein and Antibody Isolation

Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism

Authors: Bartlomiej Taciak, Maciej Bialasek, Malgorzata Kubiak, Ilona Marszalek, Malgorzata Gorczak, Olha Osadchuk, Daria Kurpiel, Damian Strzemecki, Karolina Barwik, Marcin Skorzynski, Julia Nowakowska, Waldemar Lipiński, Łukasz Kiraga, Jan Brancewicz, Robert Klopfleisch, Łukasz Krzemiński, Emilia Gorka, Anna Smolarska, Irena Padzinska-Pruszynska, Małgorzata Siemińska, Jakub Guzek, Jan Kutner, Marlena Kisiala, Krzysztof Wozniak, Giacomo Parisi, Roberta Piacentini, Luca Cassetta, Lesley M Forrester, Lubomir Bodnar, Tobias Weiss, Alberto Boffi, Paulina Kucharzewska, Tomasz P Rygiel, Magdalena Krol

Journal: Nature Communications

PubMed ID: 39900573

Doi: 10.1038/s41467-025-56637-9

Products & Services: Bacterial Expression

SKI complex loss renders 9p21.3-deleted or MSI-H cancers dependent on PELO

Authors: Patricia C Borck, Isabella Boyle, Kristina Jankovic, Nolan Bick, Kyla Foster, Anthony C Lau, Lucy I Parker-Burns, Daniel A Lubicki, Tianxia Li, Ashir A Borah, Nicholas J Lofaso, Sohani Das Sharma, Tessla Chan, Riya V Kishen, Anisah Adeagbo, Srivatsan Raghavan, Elisa Aquilanti, John R Prensner, J Michael Krill-Burger, Todd R Golub, Catarina D Campbell, Joshua M Dempster, Edmond M Chan, Francisca Vazquez.

Journal: Nature

PubMed ID: 39910293

Doi: 10.1038/s41586-024-08509-3

Development and validation of a sensitive sandwich ELISA against human PINK1

Authors: Zahra Baninameh, Jens O Watzlawik, Bernardo A Bustillos, Gabriella Fiorino, Tingxiang Yan, Szymon L Lewicki, Haonan Zhang, Dennis W Dickson, Joanna Siuda, Zbigniew K Wszolek, Wolfdieter Springer, Fabienne C Fiesel

Journal: Autophagy

PubMed ID: 39912496

Doi: 10.1080/15548627.2025.2457915

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Doublecortin restricts neuronal branching by regulating tubulin polyglutamylation

Authors: Muriel Sébastien, Alexandra L Paquette, Emily N P Prowse, Adam G Hendricks, Gary J Brouhard

Journal: Nature Communications

PubMed ID: 39966472

Doi: 10.1038/s41467-025-56951-2

Products & Services: Protein Electrophoresis and Western

Non-AUG HIV-1 uORF translation elicits specific T cell immune response and regulates viral transcript expression

Authors: Emmanuel Labaronne, Didier Décimo, Lisa Bertrand, Laura Guiguettaz, Thibault J M Sohier, David Cluet, Valérie Vivet-Boudou, Ana Luiza Chaves Valadão, Clara Dahoui, Pauline François, Isabelle Hatin, Olivier Lambotte, Assia Samri, Brigitte Autran, Lucie Etienne, Caroline Goujon, Jean-Christophe Paillart, Olivier Namy, Bertha Cecilia Ramirez, Théophile Ohlmann, Arnaud Moris, Emiliano P Ricci

Journal: Nature Communications

PubMed ID: 39966383

Doi: 10.1038/s41467-025-56772-3

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LCK-co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity

Authors: Justin B Zhang, Priyanka Chaurasia, Angela Nguyen, Zijian Huang, Trang T Nguyen, Hui Xu, Mai T Tran, Hugh H Reid, Claerwen M Jones, Stefan A Schattgen, Daniel Thiele, Paul G Thomas, Jeanette Rientjes, Kim L Good-Jacobson, Roland Ruscher, Dene R Littler, Jamie Rossjohn, Pirooz Zareie, Nicole L La Gruta

Journal: Science immunology

PubMed ID: 39982976

Doi: 10.1126/sciimmunol.adp5016

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A rational multi-target combination strategy for synergistic improvement of non-ribosomal peptide production

Authors: Hao Yan, Zhenguo Xin, Ziwei Sang, Xingwang Li, Jia Xie, Jiale Wu, Shen Pang, Ying Wen, Weishan Wang

Journal: Nature Communications

PubMed ID: 39987186

Doi: 10.1038/s41467-025-57073-5

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Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development

Authors: Feifei Yuan, Jihong Yang, Fanglin Ma, Zhe Hu, Vikas Malik, Ruge Zang, Dan Li, Xianle Shi, Xin Huang, Hongwei Zhou, Jianlong Wang

Journal: Nature Communications

PubMed ID: 39988597

Doi: 10.1038/s41467-025-57165-2

Products & Services: Protein Electrophoresis and Western

The structure of FCGBP is formed as a disulfide‐mediated homodimer between its C‐terminal domains

Authors: Erik Ehrencrona, Pablo Gallego, Sergio Trillo-Muyo, Maria-Jose Garcia-Bonete, Christian V Recktenwald, Gunnar C Hansson, Malin E V Johansson

Journal: FEBS Journal

PubMed ID: 39754272

Doi: 10.1111/febs.17383

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Perturbing Organelle-Level K+/Ca2+ Homeostasis by Nanotherapeutics for Enhancing Ion-Mediated Cancer Immunotherapy

Authors: Jun-Long Liang , Qian-Xiao Huang , Qi-Wen Chen , Xiao-Kang Jin , Zi-Yi Han 1, Ping Ji , Si-Xue Cheng , Wei-Hai Chen , Xian-Zheng Zhang

Journal: Adv Mater

PubMed ID: 39955648

Doi: 10.1002/adma.202416574

Products & Services: Recombinant Proteins

Elastin-like polypeptide: A novel titanification biomacromolecule for green and ultrafast synthesis of biotitania nanoparticles via biomimetic mineralization

Authors: Lixi Cai, Jinlin Zheng, Lixing Liu, Guangya Zhang, Yuanqing Lin

Journal: Int J Biol Macromol

PubMed ID: 40015400

Doi: 10.1016/j.ijbiomac.2025.141449

Products & Services: Gene Synthesis

A Granzyme B‑Cleavable T Cell-Targeted Bispecific Cell Vesicle Connector for Reversing New-Onset Type 1 Diabetes

Authors: Yanfang Wang, Yanping Sun, Xiuwen Zhang, Shenqiang Wang, Xuehui Huang, Kairui Xu, Yun Liu, Yingqi Huang, Jianchang Xu, Xinwei Wei, Hao Cheng, Liqiang Pan, Jinqiang Wang, Zhen Gu

Journal: Journal of the American Chemical Society

PubMed ID: 39869523

Doi: 10.1021/jacs.4c13644

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Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival

Authors: Wen Wei, Xueqin Gao, Jiawei Qian, Lei Li, Chen Zhao, Li Xu, Yanfei Zhu, Zhenzhen Liu, Nengrong Liu, Xueqing Wang, Zhicong Jin, Bowen Liu, Lan Xu, Jin Dong, Suping Zhang, Jiarong Wang, Yumu Zhang, Yao Yu, Zhanjun Yan, Yanjun Yang, Jie Lu, Yixuan Fang, Na Yuan, Jianrong Wang

Journal: Journal of Clinical Investigation

PubMed ID: 39589832

Doi: 10.1172/JCI177375.

Products & Services: Protein and Antibody Isolation

A single residue switch mediates the broad neutralization of Rotaviruses

Authors: Yang Huang, Feibo Song, Yuanjun Zeng, Hui Sun, Roufang Sheng, Xuechun Wang, Liqin Liu, Guoxing Luo, Yanan Jiang, Yaling Chen, Mengxuan Zhang, Shiyin Zhang, Ying Gu, Hai Yu, Shaowei Li, Tingdong Li, Qingbing Zheng, Shengxiang Ge, Jun Zhang & Ningshao Xia

Journal: Nature Communications

PubMed ID: 39833145

Doi: 10.1038/s41467-025-56114-3

Products & Services: Protein and Antibody Isolation

Blocking autophagosome closure manifests the roles of mammalian Atg8-family proteins in phagophore formation and expansion during nutrient starvation

Authors: Van Bui , Xinwen Liang , Yansheng Ye , William Giang , Fang Tian , Yoshinori Takahashi , Hong-Gang Wang

Journal: Autophagy

PubMed ID: 39694607

Doi: 10.1080/15548627.2024.2443300

Structural insight into synergistic activation of human 3-methylcrotonyl-CoA carboxylase

Authors: Jiayue Su, Xuyang Tian, Hang Cheng, Desheng Liu, Ziyi Wang, Shan Sun, Hong-Wei Wang, Sen-Fang Sui

Journal: NATURE STRUCTURAL & MOLECULAR BIOLOGY

PubMed ID: 39223421

Doi: doi.org/10.1038/s41594-024-01379-3

Products & Services: Catalog Peptides

Enrichment of carcinoembryonic antigen by epitope molecularly imprinted polymer based on cucurbituril host-guest interaction

Authors: Yitong Xu, Ying Zhang, Huifeng Zhang, Yi He, Qiong Jia

Journal: Journal of chromatography. A

PubMed ID: 39644742

Doi: 10.1016/j.chroma.2024.465584

Products & Services: Peptide Synthesis

Drug inhibition and substrate transport mechanisms of human VMAT2

Authors: Feiwen Wei, Huihui Liu, Wei Zhang, Jufang Wang & Yanqing Zhang

Journal: Nature Communications

PubMed ID: 39747030

Doi: 10.1038/s41467-024-55361-0

Products & Services: Protein and Antibody Isolation

Inhalable nanovesicles loaded with a STING agonist enhance CAR-T cell activity against solid tumors in the lung

Authors: Tianchuan Zhu, Yuchen Xiao, Zhenxing Chen, Hanxi Ding, Shoudeng Chen, Guanmin Jiang & Xi Huang

Journal: Nature Communications

PubMed ID: 39747173

Doi: 10.1038/s41467-024-55751-4

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A Novel Protein NLRP12-119aa that Prevents Rhabdovirus Replication by Disrupting the RNP Complex Formation

Authors: Weiwei Zheng, Xiangxiang Zhu, Tongtong Zhu, Qiang Luo, Yan Zhao, Tianjun Xu

Journal: Advanced Science

PubMed ID: 39754725

Doi: 10.1002/advs.202409953

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Enhanced Genome Editing Activity with Novel Chimeric ScCas9 Variants in Rice

Authors: Zhen Liang, Yuqing Wu, Shuke Deng, Sha Wei, Kai Zhang, Yingjie Guo

Journal: Advanced Science

PubMed ID: 39755933

Doi: 10.1002/advs.202411549

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Bidirectional histone monoaminylation dynamics regulate neural rhythmicity

Authors: Qingfei Zheng, Benjamin H. Weekley, David A. Vinson, Shuai Zhao, Ryan M. Bastle, Robert E. Thompson, Stephanie Stransky, Aarthi Ramakrishnan, Ashley M. Cunningham, Sohini Dutta, Jennifer C. Chan, Giuseppina Di Salvo, Min Chen, Nan Zhang, Jinghua Wu, Sasha L. Fulton, Lingchun Kong, Haifeng Wang, Baichao Zhang, Lauren Vostal, Akhil Upad, Lauren Dierdorff, Li Shen, Henrik Molina, …Ian Maze

Journal: Nature

PubMed ID: 39779849

Doi: 10.1038/s41586-024-08371-3

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mosGILT antibodies interfere with Plasmodium sporogony in Anopheles gambiae

Authors: Brady Dolan, Tomás Correa Gaviria, Yuemei Dong, Peter Cresswell, George Dimopoulos, Yu-Min Chuang & Erol Fikrig

Journal: Nature Communications

PubMed ID: 39799117

Doi: 10.1038/s41467-025-55902-1

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A mobile genetic element-derived primase-polymerase harbors multiple activities implicated in DNA replication and repair

Authors: Pan Fu, Yuwei Wang, Yanqiu Liu, Zhenhao Han, Zhangzhong Peng, Linfeng Liu, Wenyuan Han

Journal: Nucleic Acids Research

PubMed ID: 39797730

Doi: 10.1093/nar/gkae1318

Development of a recombinant Ang1 variant with enhanced Tie2 binding and its application to attenuate sepsis in mice

Authors: Rui Wang , Hao Li , Zhinuo Xie , Meijuan Huang , Peng Xu , Cai Yuan , Jinyu Li , Robert Flaumenhaft , Mingdong Huang , Longguang Jiang

Journal: SCIENCE ADVANCES

PubMed ID: 39813336

Doi: 10.1126/sciadv.ads1796

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Control of striatal circuit development by the chromatin regulator Zswim6

Authors: Kyuhyun Choi , Nathan T Henderson , Emily R Feierman , Sean Louzon , Jamie Galanaugh , Felicia Davatolhagh , Isha Bhandaru , David J Tischfield , Stewart A Anderson , Erica Korb , Marc V Fuccillo

Journal: SCIENCE ADVANCES

PubMed ID: 39823338

Doi: 10.1126/sciadv.adq6663

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Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice

Authors: Yuxuan Chen , Xiaohong Chen , Yao Zhang , Meng Wang , Minqi Yang , Ruiji Wang , Xiaojie Yan , Shiyi Shao , Huhu Xin , Qida Hu , Wei Wei , Yuan Ping

Journal: Sci Transl Med

PubMed ID: 39813319

Doi: 10.1126/scitranslmed.adl5800

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Tailorable biosensors for real-time monitoring of stress distribution in soft biomaterials and living tissues

Authors: Fenghou Yuan, Huitang Qi, Binghui Song, Yuntian Cui, Junsheng Zhang, Huan Liu, Bo Liu, Hai Lei, Tian Liu

Journal: nature COMMUNICATION

PubMed ID: 39870637

Doi: doi.org/10.1038/s41467-025-56422-8

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Phosphorylation of PIP2;7 by CPK28 or Phytophthora kinase effectors dampens pattern-triggered immunity in Arabidopsis

Authors: Hai Zhu, Yazhou Bao, Hao Peng, Xianglan Li, Weiye Pan, Yufeng Yang, Zifei Kuang, Peiyun Ji, Jinding Liu, Danyu Shen, Gan Ai, Daolong Dou

Journal: plant communications

PubMed ID: 39277790

Doi: 10.1016/j.xplc.2024.101135

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The Silkworm (Bombyx mori) Neuropeptide Orcokinin's Efficiency in Whitening and Skincare

Authors: Pingyang Wang, Xiao Xiao, Ya Yang, Guiqiu Liang, Shengtao Lu, Liang Tang, Hongyan Huang, Ji He, Xiaoling Tong

Journal: International Journal of Molecular Sciences

PubMed ID: 39940730

Doi: 10.3390/ijms26030961.

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Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence

Authors: Keyu Kong, Baixing Li, Yongyun Chang, Chen Zhao, Hua Qiao, Minghao Jin, Xinru Wu, Wenxuan Fan, Liao Wang, Yansong Qi, Yongsheng Xu, Zanjing Zhai, Peixiang Ma, Huiwu Li

Journal: Journal of nanobiotechnology

PubMed ID: 39844298

Doi: 10.1186/s12951-025-03103-9

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Access to Axially Chiral Biaryl Benzylamines via Ancestral Enzyme- Enabled Reductive Amination Desymmetrization

Authors: Wen-Qing, ZhengXin-Xin, ZhuZheng, ZhuTairan, YangLifen, ZhengRui, PanShenlin, WangLixin, ZhangQi, ChenJian-He, XuYongtao Xie, Yongtao Xie

Journal: ACS catalysis

Doi: 10.1021/acscatal.4c06881

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Structural insights into RNA cleavage by PIWI Argonaute

Authors: Zhiqing Li , Qikui Xu , Jing Zhong , Yan Zhang , Tianxiang Zhang , Xiaoze Ying , Xiaoli Lu , Xiaoyi Li , Li Wan , Junchao Xue , Jing Huang , Ying Zhen , Zhao Zhang， Jianping Wu , En-Zhi Shen

Journal: Nature

PubMed ID: 39814893

Doi: 10.1038/s41586-024-08438-1

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Mouse totipotent blastomere-like cells model embryogenesis from zygotic genome activation to post implantation

Authors: Bing Peng , Qingyi Wang , Feixiang Zhang , Hui Shen , Peng Du

Journal: Cell Stem Cell

PubMed ID: 39826539

Doi: doi.org/10.1016/j.stem.2024.12.006

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Ligand-Responsive Artificial Protein–Protein Communication for Field-Deployable Cell-Free Biosensing

Authors: Ke Wang , Siqian Liu , Shuqi Zhou , Aori Qileng , Dingyi Wang , Yingju Liu , Chunlai Chen , Chunyang Lei , Zhou Nie

Journal: Angew Chem Int Ed Engl

PubMed ID: 39558180

Doi: 10.1002/anie.202416671

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TMT-Based Quantitative Proteomic Profiling of Human Esophageal Cancer Cells Reveals the Potential Mechanism and Potential Therapeutic Targets Associated With Radioresistance

Authors: Aidi Gao , Chao He , Hengrui Chen , Qianlin Liu , Yin Chen , Jianying Sun , Chuanfeng Wu , Ya Pan , Sonia Rocha , Mu Wang , Jundong Zhou

Journal: Proteomics Clin Appl

PubMed ID: 39375892

Doi: 10.1002/prca.202400010

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Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson’s disease model mice

Authors: Wei Song, Zi-Ming Zhou, Le-le Zhang, Hai-Feng Shu, Jin-Ru Xia, Xia Qin, Rong Hua, Yong-Mei Zhang

Journal: Cell Death Dis

PubMed ID: 39809747

Doi: 10.1038/s41419-025-07333-5

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A high-definition spatiotemporal transcriptomic atlas of mammalian kidney development

Authors: Shan Jiang, Hao Yu, Ting Zhao, Yao Lu, Xuesong Li, Lei Gao, Jie Mi, Wenzhe Xia, Lanjun Geng, Panpan Li, Mingyue Chen, Mengyao Kang, Jiang Liu, Yuwen Ke

Journal: The Innovation

Doi: doi.org/10.1016/j.xinn.2024.100767

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Single-cycle parainfluenza virus type 5 vectors for producing recombinant proteins, including a humanized anti-V5 tag antibody

Authors: Richard E Randall , Dan Young , Maria Pisliakova , Jelena Andrejeva , Lynsey West , Luis Rossler , Volker Morath , David Hughes , Steve Goodbourn

Journal: JOURNAL OF GENERAL VIROLOGY

PubMed ID: 39786361

Doi: 10.1099/jgv.0.002061

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Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein

Authors: Marie-Lynn Cuypers; Tom Jaspers; Jarne Clerckx; Simon Leekens; Christopher Cawthorne; Guy Bormans; Frederik Cleeren; Nick Geukens; Bart De Strooper; Maarten Dewilde

Journal: Fluids and barriers of the CNS

PubMed ID: 39885527

Doi: 10.1186/s12987-025-00624-1

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Biochemical characterization and discovery of inhibitors for PfSir2A: new tricks for an old enzyme

Authors: Dickson Donu, Emily Boyle, Alyson Curry, Yana Cen

Journal: RSC Chemical biology

PubMed ID: 39897407

Doi: 10.1039/d4cb00206g

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OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced senescence in human fibroblasts

Authors: Mariarosaria De Rosa, Ryan P Barnes, Ariana C Detwiler, Prasanth R Nyalapatla, Peter Wipf, Patricia L Opresko

Journal: Nature Communications

PubMed ID: 39837827

Doi: 10.1038/s41467-024-55638-4

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Self-Cascaded Pyroptosis-STING Initiators for Catalytic Metalloimmunotherapy

Authors: Qiao Yu, Shumin Sun, Nailin Yang, Zifan Pei, Youdong Chen, Jihu Nie, Huali Lei, Li Wang, Fei Gong, Liang Cheng

Journal: Journal of the American Chemical Society

PubMed ID: 39818788

Doi: 10.1021/jacs.4c12552

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Structural insights into the mechanism of phosphate recognition and transport by XPR1

Authors: Wenhui Zhang, Yanke Chen, Zeyuan Guan, Yong Wang, Meng Tang, Zhangmeng Du, Jie Zhang, Meng Cheng, Jiaqi Zuo, Yan Liu, Qiang Wang, Yanjun Liu, Delin Zhang, Ping Yin, Ling Ma & Zhu Liu

Journal: Nature Communications

PubMed ID: 39747008

Doi: 10.1038/s41467-024-55471-9

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Complement factor H targeting antibody GT103 in refractory non-small cell lung cancer: a phase 1b dose escalation trial

Authors: Jeffrey M. Clarke, George R. Simon, Hirva Mamdani, Lin Gu, James E. Herndon II, Thomas E. Stinchcombe, Neal Ready, Jeffrey Crawford, Guru Sonpavde, Stephen Balevic, Andrew B. Nixon, Michael Campa, Elizabeth B. Gottlin, Huihua Li, Ruchi Saxena, You Wen He, Scott Antonia & Edward F. Patz Jr

Journal: Nature Communications

PubMed ID: 39747856

Doi: 10.1038/s41467-024-55092-2

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Klp2-mediated Rsp1-Mto1 colocalization inhibits microtubule-dependent microtubule assembly in fission yeast

Authors: Lingyun Nie , Wenyue Liu , Zhuobi Liang , Fan Zheng , Xing Liu , Xuebiao Yao , Shengqi Xiang , Kai Jiang , Shengnan Zheng , Chuanhai Fu

Journal: SCIENCE ADVANCES

PubMed ID: 39752482

Doi: 10.1126/sciadv.adq0670

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Large-scale multicenter study reveals anticitrullinated SR-A peptide antibody as a biomarker and exacerbator for rheumatoid arthritis

Authors: by Yang XieChaonan WeiDongdong FuWei ZhangYan DuChuncui HuangShuyan LiuRanran YaoZihao HeShenghua ZhangXu JinBin ShenLulu CaoPing WangXiangyu FangXi ZhengHongying LinXihua WeiWenhao LinMingxin BaiDanxue ZhuYingni LiYamin DingHuaqun ZhuHua YeJing HeYin SuYuan JiaHuaxiang WuYongfu WangDan XingXiaoyan QiuZhanguo LiFanlei Hu

Journal: SCIENCE ADVANCES

PubMed ID: 39752500

Doi: 10.1126/sciadv.adr8078

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Multivalent S2 subunit vaccines provide broad protection against Clade 1 sarbecoviruses in female mice

Authors: Peter J. Halfmann, Raj S. Patel, Kathryn Loeffler, Atsuhiro Yasuhara, Lee-Ann Van De Velde, Jie E. Yang, Jordan Chervin, Chloe Troxell, Min Huang, Naiying Zheng, Elizabeth R. Wright, Paul G. Thomas, Patrick C. Wilson, Yoshihiro Kawaoka & Ravi S. Kane

Journal: Nature Communications

PubMed ID: 39774966

Doi: 10.1038/s41467-025-55824-y

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Structural and bioinformatics analyses identify deoxydinucleotide-specific nucleases and their association with genomic islands in gram-positive bacteria

Authors: Sofia Mortensen, Stanislava Kuncová, Justin D Lormand, Tanner M Myers, Soo-Kyoung Kim, Vincent T Lee, Wade C Winkler, Holger Sondermann

Journal: Nucleic Acids Research

PubMed ID: 39778863

Doi: 10.1093/nar/gkae1235

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Increased SOAT2 expression in aged regulatory T cells is associated with altered cholesterol metabolism and reduced anti-tumor immunity

Authors: Mingjiong Zhang, Jiahua Cui, Haoyan Chen, Yifan Cheng, Qiaoyu Chen, Feng Zong, Xiao Lu, Lang Qin, Yu Han, Xingwang Kuai, Yuxing Zhang, Minjie Chu, Shuangshuang Wu & Jianqing Wu

Journal: Nature Communications

PubMed ID: 39805872

Doi: 10.1038/s41467-025-56002-w

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Scale-free Spatio-temporal Correlations in Conformational Fluctuations of Intrinsically Disordered Proteins

Authors: Haoyu Song, Jian Cui, Guorong Hu, Long Xiong, Yanee Wutthinitikornkit, Hai Lei, Jingyuan Li

Journal: Advanced Science

PubMed ID: 39807013

Doi: 10.1002/advs.202412989

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Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines

Authors: Lee Sherry, Mohammad W. Bahar, Claudine Porta, Helen Fox, Keith Grehan, Veronica Nasta, Helen M. E. Duyvesteyn, Luigi De Colibus, Johanna Marsian, Inga Murdoch, Daniel Ponndorf, Seong-Ryong Kim, Sachin Shah, Sarah Carlyle, Jessica J. Swanson, Sue Matthews, Clare Nicol, George P. Lomonossoff, Andrew J. Macadam, Elizabeth E. Fry, David I. Stuart, Nicola J. Stonehouse & David J. Rowlands

Journal: Nature Communications

PubMed ID: 39827284

Doi: 10.1038/s41467-025-56118-z

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Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Authors: Wenhui Li, Xianyue Jiang, Wuke Wang, Liya Hou, Runze Cai, Yongqian Li, Qiuxi Gu, Qinchang Chen, Peixiang Ma, Jin Tang, Menghao Guo, Guohui Chuai, Xingxu Huang, Jun Zhang, Qi Liu

Journal: Nature Communications

PubMed ID: 39789054

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Probing SARS-CoV-2 membrane binding peptide via single-molecule AFM-based force spectroscopy

Authors: Qingrong Zhang, Raissa S. L. Rosa, Ankita Ray, Kimberley Durlet, Gol Mohammad Dorrazehi, Rafael C. Bernardi & David Alsteens

Journal: Nature Communications

PubMed ID: 39747000

Doi: 10.1038/s41467-024-55358-9

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MCM2-7 ring closure involves the Mcm5 C-terminus and triggers Mcm4 ATP hydrolysis

Authors: Sarah V. Faull, Marta Barbon, Audrey Mossler, Zuanning Yuan, Lin Bai, L. Maximilian Reuter, Alberto Riera, Christian Winkler, Indiana Magdalou, Matthew Peach, Huilin Li & Christian Speck

Journal: Nature Communications

PubMed ID: 39747125

Doi: 10.1038/s41467-024-55479-1

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Dietary amino acids promote glucagon-like hormone release to generate global calcium waves in adipose tissues in Drosophila

Authors: Muhammad Ahmad, Shang Wu, Shengyao Luo, Wenjia Shi, Xuan Guo, Yuansheng Cao, Norbert Perrimon & Li He

Journal: Nature Communications

PubMed ID: 39747032

Doi: 10.1038/s41467-024-55371-y

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Regulation of N-degron recognin-mediated autophagy by the SARS-CoV-2 PLpro ubiquitin deconjugase

Authors: Carlos Ayala-Torres , Jiangnan Liu , Nico P Dantuma , Maria G Masucci

Journal: Autophagy

PubMed ID: 39723606

Doi: 10.1080/15548627.2024.2442849

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Reconstitution of human DNA licensing and the structural and functional analysis of key intermediates

Authors: Jennifer N. Wells, Lucy V. Edwardes, Vera Leber, Shenaz Allyjaun, Matthew Peach, Joshua Tomkins, Antonia Kefala-Stavridi, Sarah V. Faull, Ricardo Aramayo, Carolina M. Pestana, Lepakshi Ranjha & Christian Speck

Journal: Nature Communications

PubMed ID: 39779677

Doi: 10.1038/s41467-024-55772-z

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Screening the human miRNA interactome reveals coordinated up-regulation in melanoma, adding bidirectional regulation to miRNA networks

Authors: Faezeh Jame-Chenarboo , Joseph N Reyes , Nicholas M Twells , Hoi Hei Ng , Dawn Macdonald , Eva Hernando , Lara K Mahal

Journal: SCIENCE ADVANCES

PubMed ID: 39792681

Doi: 10.1126/sciadv.adr0277

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f the human autophagy factor EPG5 and the molecular basis of its conserved mode of interaction with Atg8-family proteins

Authors: Yiu Wing Sunny Cheung , Sung-Eun Nam , Gage M J Fairlie , Karlton Scheu , Jennifer M Bui , Hannah R Shariati , Jörg Gsponer , Calvin K Yip

Journal: Autophagy

PubMed ID: 39809444

Doi: 10.1080/15548627.2024.2447213

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Engineering a membrane protein chaperone to ameliorate the proteotoxicity of mutant huntingtin

Authors: Jeonghyun Oh, Christy Catherine, Eun Seon Kim, Kwang Wook Min, Hae Chan Jeong, Hyojin Kim, Mijin Kim, Seung Hae Ahn, Nataliia Lukianenko, Min Gu Jo, Hyeon Seok Bak, Sungsu Lim, Yun Kyung Kim, Ho Min Kim, Sung Bae Lee & Hyunju Cho

Journal: Nature Communications

PubMed ID: 39824813

Doi: 10.1038/s41467-025-56030-6

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Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization

Authors: Ruofei Zhang, Yanfang Shen, Xiaoying Zhou, Jianru Li, Hanqing Zhao, Zixia Zhang, Jun Zhao, Hongjun Jin, Shuanshuan Guo, Hui Ding, Guohui Nie, Zhe Zhang, Ying Wang, Xiyun Yan & Kelong Fan

Journal: Nature Communications

PubMed ID: 39837820

Doi: 10.1038/s41467-025-56134-z

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Coordinated conformational changes in P450 decarboxylases enable hydrocarbons production from renewable feedstocks

Authors: Wesley Cardoso Generoso, Alana Helen Santana Alvarenga, Isabelle Taira Simões, Renan Yuji Miyamoto, Ricardo Rodrigues de Melo, Ederson Paulo Xavier Guilherme, Fernanda Mandelli, Clelton Aparecido Santos, Rafaela Prata, Camila Ramos dos Santos, Felippe Mariano Colombari, Mariana Abrahão Bueno Morais, Rodrigo Pimentel Fernandes, Gabriela Felix Persinoti, Mario Tyago Murakami & Leticia Maria Zanphorlin

Journal: Nature Communications

PubMed ID: 39843428

Doi: 10.1038/s41467-025-56256-4

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