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Hymenopteran-specific TRPA channel from the Texas leaf cutter ant (Atta texana) is heat and cold activated and expression correlates with environmental temperature

Authors: Julia M York, Timothy N Taylor, Sarah LaPotin, Ying Lu, Ulrich Mueller

Journal: Insect Sci

PubMed ID: 38605428

Doi: 10.1111/1744-7917.13364

Products & Services: Molecular Biology Reagents

Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood

Authors: Mathias Jensen, Linn Stenfelt, Jennifer Ricci Hagman, Michael Jakob Pichler, Julia Weikum, Tine Sofie Nielsen, Annika Hult, Jens Preben Morth, Martin L Olsson, Maher Abou Hachem

Journal: Nat Microbiol

PubMed ID: 38684911

Doi: 10.1038/s41564-024-01663-4

Products & Services: Mutant Libraries

A DNA circuit that records molecular events

Authors: Mingzhi Zhang, Colin Yancey, Chao Zhang, Junyan Wang, Qian Ma, Linlin Yang, Rebecca Schulman, Da Han, Weihong Tan

Journal: SCIENCE ADVANCES

PubMed ID: 38578999

Doi: 10.1126/sciadv.adn3329

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Sequential release of interacting proteins and Ub-modifying enzymes by disulfide heterotypic ubiquitin reagents

Authors: Hongyi Cai, Xiangwei Wu, Junxiong Mao, Zebin Tong, Dingfei Yan, Yicheng Weng, Qingyun Zheng

Journal: BIOORGANIC CHEMISTRY

PubMed ID: 38387394

Doi: 10.1016/j.bioorg.2024.107186

Products & Services: Proteins, Expression, Isolation and Analysis

Buffer choice and pH strongly influence phase separation of SARS-CoV-2 nucleocapsid with RNA

Authors: Nina C Kathe, Mihajlo Novakovic, Frédéric H-T Allain

Journal: Mol Biol Cell

PubMed ID: 38568799

Doi: 10.1091/mbc.E23-12-0500

Products & Services: Molecular Biology Reagents

Lysin and Lytic Phages Reduce Vibrio Counts in Live Feed and Fish Larvae

Authors: Jaime Romero, Sergueia Blas-Chumacero, Victoria Urzúa, Alejandro Villasante, Rafael Opazo, Felipe Gajardo, Claudio D Miranda, Rodrigo Rojas

Journal: Microorganisms

PubMed ID: 38792735

Doi: 10.3390/microorganisms12050904

Products & Services: Molecular Biology Reagents

LncRNA BlncAD1 Modulates Bovine Adipogenesis by Binding to MYH10, PI3K/Akt Signaling Pathway, and miR-27a-5p/CDK6 Axis

Authors: Xin Li, Zhongyi Hou, Shengbo Meng, Qihui Jia, Shanshan Xing, Zhitong Wang, Mengjuan Chen, Huifen Xu, Ming Li, Hanfang Cai

Journal: J Agric Food Chem

PubMed ID: 38661523

Doi: 10.1021/acs.jafc.4c00165

Products & Services: Molecular Biology Reagents

OsATL32 ubiquitinates the reactive oxygen species-producing OsRac5-OsRbohB module to suppress rice immunity

Authors: Yuqing Yan, Hui Wang, Yan Bi, Jiajing Wang, Muhammad Noman, Dayong Li, Fengming Song

Journal: J Integr Plant Biol

PubMed ID: 38629772

Doi: 10.1111/jipb.13666

Products & Services: Proteins, Expression, Isolation and Analysis

Label-free detection of Aβ-42: a liquid crystal droplet approach for Alzheimer's disease diagnosis

Authors: Saumya Ranjan Pradhan, Ramadevi Suguru Pathinti, Ramesh Kandimalla, Krishnakanth Chithari, Madhava Rao Veeramalla N, Jayalakshmi Vallamkondu

Journal: RSC Adv

PubMed ID: 38628477

Doi: 10.1039/d4ra00615a

Products & Services: Proteins, Expression, Isolation and Analysis

Therapeutic application of circular RNA aptamers in a mouse model of psoriasis

Authors: Si-Kun Guo, Chu-Xiao Liu, Yi-Feng Xu, Xiao Wang, Fang Nan, Youkui Huang, Siqi Li, Shan Nan, Ling Li, Edo Kon, Chen Li, Meng-Yuan Wei, Rina Su, Jia Wei, Shiguang Peng, Nitay Ad-El, Jiaquan Liu, Dan Peer, Ting Chen, Li Yang, Ling-Ling Chen

Journal: Nat Biotechnol

PubMed ID: 38653797

Doi: 10.1038/s41587-024-02204-4

Products & Services: Proteins, Expression, Isolation and Analysis

Milligram-scale assembly and NMR fingerprint of tau fibrils adopting the Alzheimer's disease fold

Authors: Pu Duan, Nadia El Mammeri, Mei Hong

Journal: J Biol Chem

PubMed ID: 38679331

Doi: 10.1016/j.jbc.2024.107326

Products & Services: Molecular Biology Reagents

Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria

Authors: Zhenqi Zhou, Alice Ma, Timothy M Moore, Dane M Wolf, Nicole Yang, Peter Tran, Mayuko Segawa, Alexander R Strumwasser, Wenjuan Ren, Kai Fu, Jonathan Wanagat, Alexander M van der Bliek, Rachelle Crosbie-Watson, Marc Liesa, Linsey Stiles, Rebecca Acin-Perez, Sushil Mahata, Orian Shirihai, Mark O Goodarzi, Michal Handzlik, Christian M Metallo, David W Walker, Andrea L Hevener

Journal: Sci Adv

PubMed ID: 38569044

Doi: 10.1126/sciadv.adl0389

Products & Services: Proteins, Expression, Isolation and Analysis

Recombinant expression and tryptophan-assisted analysis of human sweet taste receptor T1R3's extracellular domain in sweetener interaction studies

Authors: Soo-Bin Jin, Hyun-A Kim, Ji-Ae Shin, Na-Hee Jung, Seo-Young Park, Sungguan Hong, Kwang-Hoon Kong

Journal: Prep Biochem Biotechnol

PubMed ID: 38578840

Doi: 10.1080/10826068.2024.2336985

Products & Services: Molecular Biology Reagents

Tailored UPRE2 variants for dynamic gene regulation in yeast

Authors: Chufan Xiao, Xiufang Liu, Yuyang Pan, Yanling Li, Ling Qin, Zhibo Yan, Yunzi Feng, Mouming Zhao, Mingtao Huang

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38687789

Doi: 10.1073/pnas.2315729121

Products & Services: Molecular Biology Reagents

Analysis of the Immunogenicity of African Swine Fever F317L Protein and Screening of T Cell Epitopes

Authors: Ying Huang, Wenzhu Zhai, Zhen Wang, Yuheng He, Chunhao Tao, Yuanyuan Chu, Zhongbao Pang, Hongfei Zhu, Hong Jia

Journal: Animals (Basel)

PubMed ID: 38731330

Doi: 10.3390/ani14091331

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The hsa_circ_0082152 maintains NF-κB mRNA stability by binding to MTDH to promote anti-tuberculosis drug-induced liver injury

Authors: Lin Wang, Chunyan Meng, Yifei Long, Yue Liu, Luming Yang, Xuelei Gao, Shufeng Sun, Fumin Feng

Journal: Int J Biol Macromol

PubMed ID: 38670193

Doi: 10.1016/j.ijbiomac.2024.131793

Products & Services: Molecular Biology Reagents

Flow Cytometry-Based Measurement of Antibodies Specific for Cell Surface-Expressed Folded SARS-CoV-2 Receptor-Binding Domains

Authors: Al Nasar Ahmed Sehgal, Jera Safran, Bernhard Kratzer, Pia Gattinger, Robert B Stieger, Laszlo Musiejovsky, Doris Trapin, Paul Ettel, Ulrike Körmöczi, Arno Rottal, Kristina Borochova, Yulia Dorofeeva, Inna Tulaeva, Milena Weber, Katharina Grabmeier-Pfistershammer, Thomas Perkmann, Ursula Wiedermann, Rudolf Valenta, Winfried F Pickl

Journal: Vaccines (Basel)

PubMed ID: 38675759

Doi: 10.3390/vaccines12040377

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a novel monoclonal antibody-based competitive ELISA for antibody detection against bovine leukemia virus

Authors: Jing Wang, Chao Sun, Zhe Hu, Fang Wang, Jitao Chang, Ming Gao, Dandan Ye, Qi Jia, Hui Zou, Luc Willems, Zhigang Jiang, Xin Yin

Journal: Int J Biol Macromol

PubMed ID: 38621561

Doi: 10.1016/j.ijbiomac.2024.131446

Products & Services: Proteins, Expression, Isolation and Analysis

The Ser/Thr protein kinase FonKin4-poly(ADP-ribose) polymerase FonPARP1 phosphorylation cascade is required for the pathogenicity of watermelon fusarium wilt fungus f sp

Authors: Jiajing Wang, Yizhou Gao, Xiaohui Xiong, Yuqing Yan, Jiajun Lou, Muhammad Noman, Dayong Li, Fengming Song

Journal: Front Microbiol

PubMed ID: 38690366

Doi: 10.3389/fmicb.2024.1397688

Products & Services: Molecular Biology Reagents

Immune response profiles from humans experimentally exposed to bites

Authors: Fernanda Fortes de Araujo, Maha Abdeladhim, Clarissa Teixeira, Kelly Hummer, Matthew D Wilkerson, Roseanne Ressner, Ines Lakhal-Naouar, Michael W Ellis, Claudio Meneses, Saule Nurmukhambetova, Regis Gomes, W David Tolbert, George W Turiansky, Marzena Pazgier, Fabiano Oliveira, Jesus G Valenzuela, Shaden Kamhawi, Naomi Aronson

Journal: Front Immunol

PubMed ID: 38633260

Doi: 10.3389/fimmu.2024.1335307

Products & Services: Proteins, Expression, Isolation and Analysis

High expression of PPP1CC promotes NHEJ-mediated DNA repair leading to radioresistance and poor prognosis in nasopharyngeal carcinoma

Authors: Ping Feng, Ying Wang, Na Liu, Yanming Chen, Yujun Hu, Zilu Huang, Ya Liu, Shuohan Zheng, Tongchao Jiang, Xiang Xiao, Wei Dai, Peng Huang, Yunfei Xia

Journal: Cell Death Differ

PubMed ID: 38589496

Doi: 10.1038/s41418-024-01287-5

Products & Services: Proteins, Expression, Isolation and Analysis

Lysine acetylation of Hsp163: Effect on its structure, chaperone function and influence towards the growth of Mycobacterium tuberculosis

Authors: Subhashree Barik, Alok Kumar Panda, Viplov Kumar Biswas, Sheetal Das, Ayon Chakraborty, Shibangini Beura, Rahul Modak, Sunil Kumar Raghav, Rajiv K Kar, Ashis Biswas

Journal: Int J Biol Macromol

PubMed ID: 38657928

Doi: 10.1016/j.ijbiomac.2024.131763

Products & Services: Proteins, Expression, Isolation and Analysis

Mammalian PIWI–piRNA–target complexes reveal features for broad and efficient target silencing

Authors: Zhiqing Li, Zhenzhen Li, Yuqi Zhang, Lunni Zhou, Qikui Xu, Lili Li, Lin Zeng, Junchao Xue, Huilin Niu, Jing Zhong, Qilu Yu, Dengfeng Li, Miao Gui, Yongping Huang, Shikui Tu, Zhao Zhang, Chun-Qing Song, Jianping Wu，En-Zhi Shen

Journal: Nat Struct Mol Biol

PubMed ID: 38658622

Doi: 10.1038/s41594-024-01287-6.

Products & Services: Proteins, Expression, Isolation and Analysis

Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04

Authors: Lijing Zhang, Xuping Xie, Hannan Luo, Runtong Qian, Yang Yang, Hongtao Yu, Jing Huang, Pei-Yong Shi, Qi Hu

Journal: Cell Discov

PubMed ID: 38594245

Doi: 10.1038/s41421-024-00673-0

Products & Services: Proteins, Expression, Isolation and Analysis

A long-acting FGF21 attenuates metabolic dysfunction-associated steatohepatitis-related fibrosis by modulating NR4A1-mediated Ly6C phenotypic switch in macrophages

Authors: Yue Ji, Yiliang Duan, Yuanyuan Li, Qingzhou Lu, Dingkang Liu, Yifan Yang, Ruilong Chang, Jing Tian, Wenbing Yao, Jun Yin, Xiangdong Gao

Journal: Br J Pharmacol

PubMed ID: 38679486

Doi: 10.1111/bph.16378

Products & Services: Molecular Biology Reagents

Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression

Authors: Sofie J Desmet, Jonathan Thommis, Tineke Vanderhaeghen, Edmee M F Vandenboorn, Dorien Clarisse, Yunkun Li, Steven Timmermans, Daria Fijalkowska, Dariusz Ratman, Evelien Van Hamme, Lode De Cauwer, Bart Staels, Luc Brunsveld, Frank Peelman, Claude Libert, Jan Tavernier, Karolien De Bosscher

Journal: Mol Metab

PubMed ID: 38631478

Doi: 10.1016/j.molmet.2024.101938

Products & Services: Molecular Biology Reagents

Duration of antibody response to the receptor binding domain of SARS-CoV-2 in infected or vaccinated individuals - A one year retrospective cohort study

Authors: Martin Pasev, Angelina Trifonova, Andrey Velichkov, Velislava Terzieva

Journal: Int Immunopharmacol

PubMed ID: 38621337

Doi: 10.1016/j.intimp.2024.112084

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The nematode-trapping fungus Arthrobotrys oligospora detects prey pheromones via G protein-coupled receptors

Authors: Chih-Yen Kuo, Rebecca J Tay, Hung-Che Lin, Sheng-Chian Juan, Guillermo Vidal-Diez de Ulzurrun, Yu-Chu Chang, Jason Hoki, Frank C Schroeder, Yen-Ping Hsueh

Journal: Nat Microbiol

PubMed ID: 38649409

Doi: 10.1038/s41564-024-01679-w

Products & Services: Proteins, Expression, Isolation and Analysis

Echinococcus granulosus ubiquitin-conjugating enzymes (E2D2 and E2N) promote the formation of liver fibrosis in TGFβ1-induced LX-2 cells

Authors: Xiaodi Du, Ruiqi Hua, Xue He, Wei Hou, Shengqiong Li, Aiguo Yang, Guangyou Yang

Journal: Parasit Vectors

PubMed ID: 38643149

Doi: 10.1186/s13071-024-06222-8

Products & Services: Proteins, Expression, Isolation and Analysis

Problems with paralogs: the promise and challenges of gene duplicates in evo-devo research

Authors: Kevin D Deem, Jennifer A Brisson

Journal: Integr Comp Biol

PubMed ID: 38565319

Doi: 10.1093/icb/icae009

Products & Services: Proteins, Expression, Isolation and Analysis

AKAP3-mediated type I PKA signaling is required for mouse sperm hyperactivation and fertility†

Authors: Zhongkun Liang, Chaowei Dai, Fenfen He, Yu Wang, Yihua Huang, Heying Li, Yongming Wu, Yafang Hu, Kaibiao Xu

Journal: Biol Reprod

PubMed ID: 38145487

Doi: 10.1093/biolre/ioad180

Products & Services: Proteins, Expression, Isolation and Analysis

FOXO1 is a master regulator of memory programming in CAR T cells

Authors: Alexander E Doan, Katherine P Mueller, Andy Y Chen, Geoffrey T Rouin, Yingshi Chen, Bence Daniel, John Lattin, Martina Markovska, Brett Mozarsky, Jose Arias-Umana, Robert Hapke, In-Young Jung, Alice Wang, Peng Xu, Dorota Klysz, Gabrielle Zuern, Malek Bashti, Patrick J Quinn, Zhuang Miao, Katalin Sandor, Wenxi Zhang, Gregory M Chen, Faith Ryu, Meghan Logun, Junior Hall, Kai Tan, Stephan A Grupp, Susan E McClory, Caleb A Lareau, Joseph A Fraietta, Elena Sotillo, Ansuman T Satpathy, Crystal L Mackall, Evan W Weber

Journal: Nature

PubMed ID: 38600391

Doi: 10.1038/s41586-024-07300-8

Products & Services: Molecular Biology Reagents

Circ_0087851 suppresses colorectal cancer malignant progression through triggering miR-593-3p/BAP1-mediated ferroptosis

Authors: Ming Huang, Ting Gao, Xianyong Chen, Junlei Yi, Xuan Zhou

Journal: J Cancer Res Clin Oncol

PubMed ID: 38642144

Doi: 10.1007/s00432-024-05643-3

Products & Services: Molecular Biology Reagents

Role of G326 in Determining the Aggregation Propensity of R3 Tau Repeat: Insights from Studies on R1R3 Tau Construct

Authors: Allwin Ebenezer Sahayaraj, Arshad Abdul Vahid, Asmita Dhara, Ann Teres Babu, Vinesh Vijayan

Journal: J Phys Chem B

PubMed ID: 38676652

Doi: 10.1021/acs.jpcb.4c00123

Products & Services: Molecular Biology Reagents

mA-dependent upregulation of DDX21 by super-enhancer-driven IGF2BP2 and IGF2BP3 facilitates progression of acute myeloid leukaemia

Authors: Yanchun Zhao, Yutong Zhou, Yu Qian, Wenwen Wei, Xiangjie Lin, Shihui Mao, Jie Sun, Jie Jin

Journal: Clin Transl Med

PubMed ID: 38572589

Doi: 10.1002/ctm2.1628

Products & Services: Proteins, Expression, Isolation and Analysis

Corinthian Currants Promote the Expression of Paraoxonase-1 and Enhance the Antioxidant Status in Serum and Brain of 5xFAD Mouse Model of Alzheimer's Disease

Authors: Dimitris Lymperopoulos, Anastasia-Georgia Dedemadi, Maria-Lydia Voulgari, Eirini Georgiou, Ioannis Dafnis, Christina Mountaki, Eirini A Panagopoulou, Michalis Karvelas, Antonia Chiou, Vaios T Karathanos, Angeliki Chroni

Journal: Biomolecules

PubMed ID: 38672443

Doi: 10.3390/biom14040426

Products & Services: Molecular Biology Reagents

Identification of hyperthermophilic D-allulose 3-epimerase from Thermotoga sp and its application as a high-performance biocatalyst for D-allulose synthesis

Authors: Ji-Dong Shen, Bao-Ping Xu, Te-Li Yu, Yong-Xiang Fei, Xue Cai, Liang-Gang Huang, Li-Qun Jin, Zhi-Qiang Liu, Yu-Guo Zheng

Journal: Bioprocess Biosyst Eng

PubMed ID: 38676737

Doi: 10.1007/s00449-024-02989-3

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Determination of optimum levels of binding antibody units (BAU) of new quantitative chemiluminescent immuno-assay (CLIA) in COVID-19 vaccinated volunteer blood donors

Authors: Aseem Kumar Tiwari, Geet Aggarwal, Pratibha Kale, Neeti Yadav, Virendra Kumar, Gargi Singh, K Cheirmaraj, K Krishnan

Journal: Transfus Apher Sci

PubMed ID: 38678985

Doi: 10.1016/j.transci.2024.103937

Products & Services: Proteins, Expression, Isolation and Analysis

Regulation by the RNA-binding protein Unkempt at its effector interface

Authors: Kriti Shah, Shiyang He, David J Turner, Joshua Corbo, Khadija Rebbani, Daniel Dominguez, Joseph M Bateman, Sihem Cheloufi, Cátia Igreja, Eugene Valkov, Jernej Murn

Journal: Nat Commun

PubMed ID: 38605040

Doi: 10.1038/s41467-024-47449-4

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Structural basis of exoribonucleasemediated mRNA transcription termination

Authors: Yuan Zeng, Hong-Wei Zhang, Xiao-Xian Wu, Yu Zhang

Journal: Nature

PubMed ID: 38538796

Doi: doi.org/10.1038/s41586-024-07240-3

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HLA-C*04:09N is expressed at the cell surface and triggers peptide-specific T-cell activation

Authors: Carlotta Welters, Marthe-Lina Welters, Serena Stadler, Lars Bullinger, Julian Strobel, Holger Hackstein, Arunraj Dhamodaran, Thomas Blankenstein, Leo Hansmann

Journal: Haematologica

PubMed ID: 37767552

Doi: 10.3324/haematol.2023.283812

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Identification of PEX5-PTS1 Interaction Inhibitors through Fluorescence Polarization-Based High-Throughput Screening

Authors: Trong-Nhat Phan, Kyu-Ho Paul Park, David Shum, Joo Hwan No

Journal: Molecules

PubMed ID: 38675653

Doi: 10.3390/molecules29081835

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Synthetic Peptides Selected by Immunoinformatics as Potential Tools for the Specific Diagnosis of Canine Visceral Leishmaniasis

Authors: Gabriel Moreira, Rodrigo Maia, Nathália Soares, Thais Ostolin, Wendel Coura-Vital, Rodrigo Aguiar-Soares, Jeronimo Ruiz, Daniela Resende, Rory de Brito, Alexandre Reis, Bruno Roatt

Journal: Microorganisms

PubMed ID: 38792746

Doi: 10.3390/microorganisms12050906

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Quantitation of Enterovirus A71 Empty and Full Particles by Sedimentation Velocity Analytical Ultracentrifugation

Authors: Anna Yang, Yun Luo, Jie Yang, Tingbo Xie, Wenhui Wang, Xin Wan, Kaiwen Wang, Deqin Pang, Dongsheng Yang, Hanyu Dai, Jie Wu, Shengli Meng, Jing Guo, Zejun Wang, Shuo Shen

Journal: Viruses

PubMed ID: 38675915

Doi: 10.3390/v16040573

Products & Services: Proteins, Expression, Isolation and Analysis

Use of in silico approaches, synthesis and profiling of Pan-filovirus GP-1,2 preprotein specific antibodies

Authors: Maciej Wiśniewski, Peace Babirye, Carol Musubika, Eleni Papakonstantinou, Samuel Kirimunda, Michal Łaźniewski, Teresa Szczepińska, Moses L Joloba, Elias Eliopoulos, Erik Bongcam-Rudloff, Dimitrios Vlachakis, Anup Kumar Halder, Dariusz Plewczyński, Misaki Wayengera

Journal: Brief Funct Genomics

PubMed ID: 38605526

Doi: 10.1093/bfgp/elae012

Products & Services: Proteins, Expression, Isolation and Analysis

Antibody-blocking of a tick transporter impairs Anaplasma phagocytophilum colonization in Haemaphysalis longicornis ticks

Authors: Prachi Namjoshi, Donald M Lubembe, Hameeda Sultana, Girish Neelakanta

Journal: Sci Rep

PubMed ID: 38637614

Doi: 10.1038/s41598-024-59315-w

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Epitope mapping and a candidate vaccine design from canine distemper virus

Authors: Camila Pereira Dos Santos, Jerlane Tarcilia Gomes Telles, Georgia de Freitas Guimarães, Laura Helena Vega Gonzales Gil, Amanda Mota Vieira, Jose Wilton Pinheiro Junior, Carlos Eduardo Calzavara-Silva, Rita de Cássia CarvalhoMaia

Journal: Open Vet J

PubMed ID: 38808294

Doi: 10.5455/OVJ.2024.v14.i4.9

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BRD2-specific inhibitor, BBC0403, inhibits the progression of osteoarthritis pathogenesis in osteoarthritis-induced C57BL/6 male mice

Authors: Hyemi Lee, Jiho Nam, Hahyeong Jang, Young-Sik Park, Min-Hee Son, In-Hyun Lee, Seong-Il Eyun, Jae-Hyun Yang, Jimin Jeon, Siyoung Yang

Journal: Br J Pharmacol

PubMed ID: 38600628

Doi: 10.1111/bph.16359

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Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum

Authors: Takaaki Fujiwara, Eriko Mano, Eriko Nango

Journal: FEBS Lett

PubMed ID: 38649293

Doi: 10.1002/1873-3468.14886

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The Bifunctional Effects of Lactoferrin (LFcinB11) in Inhibiting Neural Cell Adhesive Molecule (NCAM) Polysialylation and the Release of Neutrophil Extracellular Traps (NETs)

Authors: Bo Lu, Si-Ming Liao, Shi-Jie Liang, Li-Xin Peng, Jian-Xiu Li, Xue-Hui Liu, Ri-Bo Huang, Guo-Ping Zhou

Journal: Int J Mol Sci

PubMed ID: 38731861

Doi: 10.3390/ijms25094641

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Constructing an Antibiotic-Free Protein Expression System for Ovalbumin Biosynthesis in Probiotic Nissle 1917

Authors: Cheng Liu, Xueqin Lv, Long Liu, Jianghua Li, Guocheng Du, Jian Chen, Yanfeng Liu

Journal: J Agric Food Chem

PubMed ID: 38574273

Doi: 10.1021/acs.jafc.4c00827

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Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer's disease by inhibiting neuroinflammation and neuronal necroptosis

Authors: Chong Xu, Yilan Mei, Ruihan Yang, Qiudan Luo, Jienian Zhang, Xiaolin Kou, Jianfeng Hu, Yujie Wang, Yue Li, Rong Chen, Zhengping Zhang, Yuyuan Yao, Jian Sima

Journal: Cell Biosci

PubMed ID: 38678262

Doi: 10.1186/s13578-024-01230-8

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Intratumoural delivery of TRAIL mRNA induces colon cancer cell apoptosis

Authors: Tingxuan Gu, Mengqiao Wang, Xiaorong Fu, Xueli Tian, Juanjuan Bi, Ning Lu, Chen Chen, Shijia Yan, Ang Li, Luyun Wang, Xiang Li, Kangdong Liu, Zigang Dong

Journal: Biomed Pharmacother

PubMed ID: 38636395

Doi: 10.1016/j.biopha.2024.116603

Products & Services: Recombinant Proteins

CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition

Authors: Irene Andreu-Saumell, Alba Rodriguez-Garcia, Vanessa Mühlgrabner, Marta Gimenez-Alejandre, Berta Marzal, Joan Castellsagué, Fara Brasó-Maristany, Hugo Calderon, Laura Angelats, Salut Colell, Mara Nuding, Marta Soria-Castellano, Paula Barbao, Aleix Prat, Alvaro Urbano-Ispizua, Johannes B Huppa, Sonia Guedan

Journal: Nat Commun

PubMed ID: 38670972

Doi: 10.1038/s41467-024-47799-z

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An ultraviolet-driven rescue pathway for oxidative stress to eye lens protein human gamma-D crystallin

Authors: Jake A Hill, Yvonne Nyathi, Sam Horrell, David von Stetten, Danny Axford, Robin L Owen, Godfrey S Beddard, Arwen R Pearson, Helen M Ginn, Briony A Yorke

Journal: Commun Chem

PubMed ID: 38600176

Doi: 10.1038/s42004-024-01163-w

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Online monitoring of protein refolding in inclusion body processing using intrinsic fluorescence

Authors: Chika Linda Igwe, Don Fabian Müller, Florian Gisperg, Jan Niklas Pauk, Matthias Kierein, Mohamed Elshazly, Robert Klausser, Julian Kopp, Oliver Spadiut, Eva Přáda Brichtová

Journal: Anal Bioanal Chem

PubMed ID: 38573344

Doi: 10.1007/s00216-024-05249-1

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Immunometric and functional measurement of endogenous vasoinhibin in human sera

Authors: Magdalena Zamora, David Harris, Nils Davies, Johannes Ebnet, Peter Radermacher, Cosima Brucker, Christiane Waller, Juan Pablo Robles, Thomas Bertsch, Carmen Clapp, Jakob Triebel

Journal: Front Endocrinol (Lausanne)

PubMed ID: 38742198

Doi: 10.3389/fendo.2024.1345996

Products & Services: Recombinant Proteins

The Female-Biased General Odorant Binding Protein 2 of Displays Binding Affinity for Biologically Active Host Plant Volatiles

Authors: Jingjing Tu, Zehua Wang, Fan Yang, Han Liu, Guanghang Qiao, Aihuan Zhang, Shanning Wang

Journal: Biology (Basel)

PubMed ID: 38666886

Doi: 10.3390/biology13040274

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Streptococcus pneumoniae endopeptidase O induces trained immunity and confers protection against various pathogenic infections

Authors: Wenlong Xu, Yuan Yuan, Zhaoche Shu, Ting Guo, Bichen Liu, Jiangming Xiao, Lian Li, Yibin Yin, Xuemei Zhang

Journal: Clin Immunol

PubMed ID: 38663493

Doi: 10.1016/j.clim.2024.110226

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P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by

Authors: Michal Caspi Tal, Paige S Hansen, Haley A Ogasawara, Qingying Feng, Regan F Volk, Brandon Lee, Sara E Casebeer, Grace S Blacker, Maia Shoham, Sarah D Galloway, Anne L Sapiro, Beth Hayes, Laughing Bear Torrez Dulgeroff, Tal Raveh, Venkata Raveendra Pothineni, Hari-Hara Sk Potula, Jayakumar Rajadas, Effie E Bastounis, Seemay Chou, William H Robinson, Jenifer Coburn, Irving L Weissman, Balyn W Zaro

Journal: biorxiv

PubMed ID: 38746193

Doi: 10.1101/2024.04.29.591704

Products & Services: Proteins, Expression, Isolation and Analysis

Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system

Authors: Lijie Guo, Pingping Huang, Zhaoxing Li, Young-Cheul Shin, Purui Yan, Meiling Lu, Meirong Chen, Yibei Xiao

Journal: Nat Chem Biol

PubMed ID: 37932527

Doi: 10.1038/s41589-023-01478-0

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Mechanosensitive channel MscL gating transitions coupling with constriction point shift

Authors: Mingfeng Zhang, Siyang Tang, Xiaomin Wang, Sanhua Fang, Yuezhou Li

Journal: Protein Sci

PubMed ID: 38501596

Doi: 10.1002/pro.4965

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An Omicron-specific, self-amplifying mRNA booster vaccine for COVID-19: a phase 2/3 randomized trial

Authors: Amit Saraf, Rohan Gurjar, Swarnendu Kaviraj, Aishwarya Kulkarni, Durgesh Kumar, Ruta Kulkarni, Rashmi Virkar, Jayashri Krishnan, Anjali Yadav, Ekta Baranwal, Ajay Singh, Arjun Raghuwanshi, Praveen Agarwal, Laxman Savergave, Sanjay Singh; GEMCOVAC-OM Study Investigators

Journal: nature medicine

PubMed ID: 38637636

Doi: 10.1038/s41591-024-02955-2

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Engineering allorejection-resistant CAR-NKT cells from hematopoietic stem cells for off-the-shelf cancer immunotherapy

Authors: Yan-Ruide Li, Yang Zhou 1, Jiaji Yu, Yichen Zhu, Derek Lee, Enbo Zhu, Zhe Li, Yu Jeong Kim, Kuangyi Zhou, Ying Fang, Zibai Lyu, Yuning Chen, Yanxin Tian, Jie Huang, Xinjian Cen, Tiffany Husman, Jae Min Cho, Tzung Hsiai, Jin J Zhou, Pin Wang, Benjamin R Puliafito, Sarah M Larson, Lili Yang

Journal: Molecular Therapy

PubMed ID: 38584391

Doi: 10.1016/j.ymthe.2024.04.005

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AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans

Authors: Lilit Grigoryan, Yupeng Feng, Lorenza Bellusci, Lilin Lai, Bushra Wali, Madison Ellis, Meng Yuan, Prabhu S Arunachalam, Mengyun Hu, Sangeeta Kowli, Sheena Gupta, Sofia Maysel-Auslender, Holden T Maecker, Hady Samaha, Nadine Rouphael, Ian A Wilson, Alberto C Moreno, Mehul S Suthar, Surender Khurana, Stéphane Pillet, Nathalie Charland, Brian J Ward, Bali Pulendran

Journal: Science immunology

PubMed ID: 38579013

Doi: 10.1126/sciimmunol.adi8039

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Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination

Authors: Lorenzo Galanti, Martina Peritore, Robert Gnügge, Elda Cannavo, Johannes Heipke, Maria Dilia Palumbieri, Barbara Steigenberger, Lorraine S Symington, Petr Cejka, Boris Pfander

Journal: Nature Communications

PubMed ID: 38570537

Doi: 10.1038/s41467-024-46951-z

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CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits

Authors: Annemart Koornneef, Kanika Vanshylla, Gijs Hardenberg, Lucy Rutten, Nika M Strokappe, Jeroen Tolboom, Jessica Vreugdenhil, Karin Feddes-de Boer, Aditya Perkasa, Sven Blokland, Judith A Burger, Wei-Chiao Huang, Jonathan F Lovell, Danielle van Manen, Rogier W Sanders, Roland C Zahn, Hanneke Schuitemaker, Johannes P M Langedijk, Frank Wegmann

Journal: Nature Communications

PubMed ID: 38605096

Doi: 10.1038/s41467-024-47492-1

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Author Correction: Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae

Authors: San Hadži, Zala Živič, Matic Kovačič, Uroš Zavrtanik, Sarah Haesaerts, Daniel Charlier, Janez Plavec, Alexander N Volkov, Jurij Lah, Remy Loris

Journal: Nat Commun

PubMed ID: 38664458

Doi: 10.1038/s41467-024-47946-6

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Dual-responsive nanocarriers for efficient cytosolic protein delivery and CRISPR-Cas9 gene therapy of inflammatory skin disorders

Authors: Echuan Tan, Tao Wan, Qi Pan, Jianan Duan, Song Zhang, Ruijue Wang, Peng Gao, Jia Lv, Hui Wang, Dali Li, Yuan Ping, Yiyun Cheng

Journal: SCIENCE ADVANCES

PubMed ID: 38630829

Doi: 10.1126/sciadv.adl4336

A selective Fibroblast Growth Factor Receptor 1/2 PROTAC degrader with 1 antitumor activity

Authors: Ying Kong , Xinyue Zhao , Zhaofu Wang , Siqi Yuan , Sheng Chen , Shidi Lou , Shichao Ma , Yunfeng Li , Xinghao Wang , Yangfeng Ge , Guobin Li , Hongbing Yang , Mengxi Zhao , Dandan Li , Hailong Zhang , Wenfu Tan , Juan Wang

Journal: Molecular cancer therapeutics

PubMed ID: 38647531

Doi: 10.1158/1535-7163.MCT-23-0719

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Ferroptosis and HMGB2 induced calreticulin translocation required for immunogenic cell death are controlled by the nuclear exporter XPO1

Authors: Ian Blair, Jingqi Fan, Kevin Gillespie, Clementina Mesaros

Journal: Res Sq

PubMed ID: 38496553

Doi: 10.21203/rs.3.rs-4009459/v1

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Validation for the function of protein C in mouse models

Authors: Ya Liu, Maoping Cai, Yan Chen, Guocai Wu, Songyu Li, Zhanghui Chen

Journal: PeerJ

PubMed ID: 38680896

Doi: 10.7717/peerj.17261

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Protein localization of aquaporins in the adult female disease vector mosquito,

Authors: Britney Picinic, Jean-Paul V Paluzzi, Andrew Donini

Journal: Front Insect Sci

PubMed ID: 38699443

Doi: 10.3389/finsc.2024.1365651

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Transmembrane conformation of the envelope protein of an alpha coronavirus, NL63

Authors: Iva Sučec, Yanina Pankratova, Mriganka Parasar, Mei Hong

Journal: Protein Sci

PubMed ID: 38501465

Doi: 10.1002/pro.4923

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FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy

Authors: Jack D Chan, Christina M Scheffler, Isabelle Munoz, Kevin Sek, Joel N Lee, Yu-Kuan Huang, Kah Min Yap, Nicole Y L Saw, Jasmine Li, Amanda X Y Chen, Cheok Weng Chan, Emily B Derrick, Kirsten L Todd, Junming Tong, Phoebe A Dunbar, Jiawen Li, Thang X Hoang, Maria N de Menezes, Emma V Petley, Joelle S Kim, Dat Nguyen, Patrick S K Leung, Joan So, Christian Deguit, Joe Zhu, Imran G House, Lev M Kats, Andrew M Scott, Benjamin J Solomon, Simon J Harrison, Jane Oliaro, Ian A Parish, Kylie M Quinn, Paul J Neeson, Clare Y Slaney, Junyun Lai, Paul A Beavis, Phillip K Darcy

Journal: Nature

PubMed ID: 38600376

Doi: 10.1038/s41586-024-07242-1

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Stepwise activation of a metabotropic glutamate receptor

Authors: Kaavya Krishna Kumar, Haoqing Wang, Chris Habrian, Naomi R Latorraca, Jun Xu, Evan S O'Brien, Chensong Zhang, Elizabeth Montabana, Antoine Koehl, Susan Marqusee, Ehud Y Isacoff, Brian K Kobilka

Journal: Nature

PubMed ID: 38632403

Doi: 10.1038/s41586-024-07327-x

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Development of a latex agglutination test based on VH antibody fragment for detection of Streptococcus suis serotype 2

Authors: Kiratika Chidkoksung, Nattihda Parakasikron, Suphachai Nuanualsuwan, Kannika Khantasup

Journal: PLoS ONE

PubMed ID: 38568909

Doi: 10.1371/journal.pone.0299691

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Biophysical characterization and insights into the oligomeric nature of CD2-associated protein

Authors: Abrar H Qadri, Jyotsana Prajapati, Iqball Faheem, Utsa Bhattacharjee, Hari Krishnan Padmanaban, Sandeep Kn Mulukala, Anil K Pasupulati

Journal: Int J Biochem Mol Biol

PubMed ID: 38765876

Doi: 10.62347/UVSH8436

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Artemisinin Confers Cytoprotection toward Hydrogen Peroxide-Induced Cell Apoptosis in Retinal Pigment Epithelial Cells in Correlation with the Increased Acetylation of Histone H4 at Lysine 8

Authors: Chao Yang, Lijun Ge, Xiyong Yu, Philip Lazarovici, Wenhua Zheng

Journal: Molecules

PubMed ID: 38675608

Doi: 10.3390/molecules29081789

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Antibacterial and Hemolytic Activity of Antimicrobial Hydrogels Utilizing Immobilized Antimicrobial Peptides

Authors: Edvin Blomstrand, Elin Posch, Annija Stepulane, Anand K Rajasekharan, Martin Andersson

Journal: Int J Mol Sci

PubMed ID: 38673786

Doi: 10.3390/ijms25084200

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Injectable self-assembled GDF5-containing dipeptide hydrogels for enhanced tendon repair

Authors: Ming Zhang, Hao Wang, Guan-Chun Dai, Pan-Pan Lu, Yu-Cheng Gao, Mu-Ming Cao, Ying-Juan Li, Yun-Feng Rui

Journal: Mater Today Bio

PubMed ID: 38600922

Doi: 10.1016/j.mtbio.2024.101046

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A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: protection of African green monkeys from COVID-19 disease

Authors: Sham Nambulli, Nicolas Escriou, Linda J Rennick, Matthew J Demers, Natasha L Tilston-Lunel, Anita K McElroy, Dominique J Barbeau, Nicholas A Crossland, Ryan M Hoehl, Sabrina Schrauf, Alexander G White, H Jacob Borish, Jaime A Tomko, Lonnie J Frye, Charles A Scanga, JoAnne L Flynn, Annette Martin, Christiane Gerke, Amy L Hartman, W Paul Duprex

Journal: J Virol

PubMed ID: 38563762

Doi: 10.1128/jvi.01762-23

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Targeting the heparan sulfate-binding site of RAGE with monoclonal antibodies

Authors: Chihyean Ong, Miaomiao Li, Ding Xu

Journal: Glycobiology

PubMed ID: 38181393

Doi: 10.1093/glycob/cwae001

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Deciphering S100B Allosteric Signaling: The Role of a Peptide Target, TRTK-12, as an Ensemble Modulator

Authors: Riya Samanta, Xinhao Zhuang, Kristen M Varney, David J Weber, Silvina Matysiak

Journal: J Chem Inf Model

PubMed ID: 38605537

Doi: 10.1021/acs.jcim.4c00116

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Blocking group 2 innate lymphoid cell activation and macrophage M2 polarization: potential therapeutic mechanisms in ovalbumin-induced allergic asthma by calycosin

Authors: Chunyan Tian, Qi Liu, Xiaoyu Zhang, Zhuying Li

Journal: BMC Pharmacol Toxicol

PubMed ID: 38650035

Doi: 10.1186/s40360-024-00751-9

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The grapevine miR827a regulates the synthesis of stilbenes by targeting VqMYB14 and gives rise to susceptibility in plant immunity

Authors: Yangyang Luo, Linxia Wang, Jie Zhu, Jingwen Tian, Lin You, Qin Luo, Jia Li, Qian Yao, Dong Duan

Journal: Theor Appl Genet

PubMed ID: 38582777

Doi: 10.1007/s00122-024-04599-9

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mARC1 in MASLD: Modulation of lipid accumulation in human hepatocytes and adipocytes

Authors: Amanda K Jones, Besnik Bajrami, Morgan K Campbell, Abdullah Mesut Erzurumluoglu, Qiusha Guo, Hongxing Chen, Xiaomei Zhang, Svetlana Zeveleva, David Kvaskoff, Andreas-David Brunner, Stefanie Muller, Vasudha Gathey, Rajvee M Dave, James W Tanner, Sophia Rixen, Michel A Struwe, Kathryn Phoenix, Kaitlyn J Klumph, Heather Robinson, Daniel Veyel, Annkatrin Muller, Boris Noyvert, Boris Alexander Bartholdy, Agnes A Steixner-Kumar, Jan Stutzki, Dmitriy Drichel, Steffen Omland, Ryan Sheehan, Jon Hill, Tom Bretschneider, Dirk Gottschling, Axel J Scheidig, Bernd Clement, Martin Giera, Zhihao Ding, John Broadwater, Curtis R Warren

Journal: Hepatol Commun

PubMed ID: 38619429

Doi: 10.1097/HC9.0000000000000365

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Characterization of genital chlamydia trachomatis infection among women attending infertility and gynecology clinics in Hunan, China

Authors: Qianting Zhou, Jiayan Li, Lipei Luo, Shuling Min, Li Wang, Lixiu Peng, Yinglan Hou, Ping He, Song He, Shixing Tang, Hongliang Chen

Journal: BMC Infect Dis

PubMed ID: 38622501

Doi: 10.1186/s12879-024-09254-8

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Cryo-EM structure of the human Asc-1 transporter complex

Authors: Yaning Li , Yingying Guo, Angelika Bröer, Lu Dai, Stefan Brӧer , Renhong Yan

Journal: Nat Commun

PubMed ID: 38589439

Doi: 10.1038/s41467-024-47468-1

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Developing Plant Exosomes as an Advanced Delivery System for Cosmetic Peptide

Authors: Jiali Hou, Wei Wei, Zaijun Geng, Zhenxing Zhang, Hui Yang, Xuhui Zhang, Li Li, Qi Gao

Journal: ACS Appl Bio Mater

PubMed ID: 38598772

Doi: 10.1021/acsabm.4c00096

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in Ticks Blood-Feeding on Migratory Birds in Sweden

Authors: Peter Wilhelmsson, Malin Lager, Thomas G T Jaenson, Jonas Waldenström, Björn Olsen, Per-Eric Lindgren

Journal: Microorganisms

PubMed ID: 38674679

Doi: 10.3390/microorganisms12040735

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Gene replacement therapy in Bietti crystalline corneoretinal dystrophy: an open-label, single-arm, exploratory trial

Authors: Jinyuan Wang, Jinlu Zhang, Shicheng Yu, Hongyan Li, Shaohong Chen, Jingting Luo, Haibo Wang, Yuxia Guan, Haihan Zhang, Shiyi Yin, Huili Wang, Heping Li, Junle Liu, Jingyuan Zhu, Qiong Yang, Ying Sha, Chuan Zhang, Yuhang Yang, Xuan Yang, Xifang Zhang, Xiuli Zhao, Likun Wang, Liping Yang, Wenbin Wei

Journal: Signal Transduct Target Ther

PubMed ID: 38653979

Doi: 10.1038/s41392-024-01806-3

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Co-clustering of EphB6 and ephrinB1 in trans restrains cancer cell invasion

Authors: Lung-Yu Liang, Niall D Geoghegan, Michael Mlodzianoski, Andrew Leis, Lachlan W Whitehead, Minglyanna G Surudoi, Samuel N Young, Peter Janes, Doulin Shepherd, Debnath Ghosal, Kelly L Rogers, James M Murphy, Isabelle S Lucet

Journal: Commun Biol

PubMed ID: 38627519

Doi: 10.1038/s42003-024-06118-4

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Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in WCFS1

Authors: Michael Brasino, Eli Wagnell, E Sila Ozdemir, Srivathsan Ranganathan, Justin Merritt

Journal: Microbiol Spectr

PubMed ID: 38687019

Doi: 10.1128/spectrum.00517-24

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The SARS-CoV-2 Spike Protein Receptor-Binding Domain Expressed in Rice Callus Features a Homogeneous Mix of Complex-Type Glycans

Authors: Guillermo Sobrino-Mengual, Victoria Armario-Nájera, Juliette Balieu, Marie-Laure Walet-Balieu, Andrea Saba-Mayoral, Ana M Pelacho, Teresa Capell, Paul Christou, Muriel Bardor, Patrice Lerouge

Journal: Int J Mol Sci

PubMed ID: 38674051

Doi: 10.3390/ijms25084466

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Higher correlation between neutralizing antibodies and surrogate neutralizing or binding antibodies in COVID-19 patients than vaccine recipients

Authors: Hatairat Lerdsamran, Ratikorn Anusorntanawat, Kantima Sangsiriwut, Suteema Sawadpongpan, Jarunee Prasertsopon, Nattakarn Thinpan, Poj Intalapaporn, Ranida Techasuwanna, Pilailuk Okada, Pilaipan Puthavathana

Journal: PLoS ONE

PubMed ID: 38626137

Doi: 10.1371/journal.pone.0298033

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Catalytic specificity and crystal structure of cystathionine γ-lyase from Pseudomonas aeruginosa

Authors: Marco Pedretti, Carmen Fernández-Rodríguez, Carolina Conter, Iker Oyenarte, Filippo Favretto, Adele di Matteo, Paola Dominici, Maria Petrosino, Maria Luz Martinez-Chantar, Tomas Majtan, Alessandra Astegno, Luis Alfonso Martínez-Cruz

Journal: Sci Rep

PubMed ID: 38654065

Doi: 10.1038/s41598-024-57625-7

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Correlates of protection against symptomatic SARS-CoV-2 in vaccinated children

Authors: Youjia Zhong, Alicia Y H Kang, Carina J X Tay, Hui' En Li, Nurul Elyana, Chee Wah Tan, Wee Chee Yap, Joey M E Lim, Nina Le Bert, Kuan Rong Chan, Eugenia Z Ong, Jenny G Low, Lynette P Shek, Elizabeth Huiwen Tham, Eng Eong Ooi

Journal: Nat Med

PubMed ID: 38689059

Doi: 10.1038/s41591-024-02962-3

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Identification and structural characterization of small molecule inhibitors of PINK1

Authors: Shafqat Rasool, Tara Shomali, Luc Truong, Nathalie Croteau, Simon Veyron, Bernardo A Bustillos, Wolfdieter Springer, Fabienne C Fiesel, Jean-François Trempe

Journal: Sci Rep

PubMed ID: 38565869

Doi: 10.1038/s41598-024-58285-3

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Evolutionarily conserved ovarian fluid proteins are responsible for extending egg viability in salmonid fish

Authors: Aurélie Gueho, Daniel Żarski, Hélène Rime, Blandine Guével, Emmanuelle Com, Régis Lavigne, Thaovi Nguyen, Jérôme Montfort, Charles Pineau, Julien Bobe

Journal: Sci Rep

PubMed ID: 38671194

Doi: 10.1038/s41598-024-60118-2

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