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Splenic red pulp macrophages eliminate the liver-resistant Streptococcus pneumoniae from the blood circulation of mice
Authors: Haoran An, Yijia Huang, Zhifeng Zhao, Kunpeng Li, Jingjing Meng, Xueting Huang, Xianbin Tian, Hongyu Zhou, Jiamin Wu, Qionghai Dai, Jing-Ren Zhang
Journal: SCIENCE ADVANCES
PubMed ID: 40073120
Doi: 10.1126/sciadv.adq6399
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PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover
Authors: Takashi Ono, Yoshitaka Taketomi, Takayoshi Higashi, Hiroyasu Sato, Chika Mochizuki-Ono, Yuki Nagasaki, Takashi Ueta, Takashi Miyai, Suzumi M Tokuoka, Yoshiya Oda, Yasumasa Nishito, Tomio Ono, Choji Taya, Satoru Arata, Sumiko Watanabe, Tomoyoshi Soga, Tetsuya Hirabayashi, Makoto Aihara, Makoto Murakami
Journal: Nature Communications
PubMed ID: 40082403
Doi: 10.1038/s41467-025-57402-8
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Machine Learning-Aided Identification of Fecal Extracellular Vesicle microRNA Signatures for Noninvasive Detection of Colorectal Cancer
Authors: Zhaowei Zhang, Xuyang Liu, Chuanyue Peng, Rui Du, Xiaoqin Hong, Jia Xu, Jiaming Chen, Xiaomin Li, Yujing Tang, Yuwei Li, Yang Liu, Chen Xu, Dingbin Liu
Journal: ACS Nano
PubMed ID: 40033785
Doi: 10.1021/acsnano.4c16698
Products & Services: Synthetic Guide RNA   Catalog Gene Editing   
GPR132 regulates the function of NK cells through the Gαs/CSK/ZAP70/NF-κB signaling pathway as a potential immune checkpoint
Authors: Xinhui Hui, Min Xue, Yaojun Ren, Yiran Chen, Xuenan Chen, Muhammad Asad Farooq, Yuzhou Ji, Weirong Zhan, Yunhe Huang, Bingtan Du, Jie Yao, Yixin Duan, Wenzheng Jiang
Journal: Sci Adv
PubMed ID: 40043109
Doi: doi/10.1126/sciadv.adr9395
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Manganese-Driven Plasmid Nanofibers Formed In Situ for Cancer Gene Delivery and Metalloimmunotherapy
Authors: Jiexin Li, Ruiqi Yang, Chen Zhang, Jonathan F Lovell, Yumiao Zhang
Journal: J Am Chem Soc
PubMed ID: 40065259
Doi: 10.1021/jacs.4c18511
Products & Services: Recombinant Proteins   
Meiotic crossovers revealed by differential visualization of homologous chromosomes using enhanced haplotype oligo-painting in cucumber
Authors: Yafeng Wu,Zixuan Chen,Fengxiang Chen,Juan Su,Jianyu Han,Songqin Liu
Journal: Plant Biotechnol J
PubMed ID: 39661709
Doi: 10.1111/pbi.14546
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Examining the Role of Threonine Phosphorylation in Ubiquitin’s Function Using Chemical Protein Synthesis
Authors: Bingji Wang, Chuntong Li, Fangyu Zhao, Luyu Shi, Xu Li, Yijie Liu, Shuzhe Sun, Ligong Yuan, Maoshen Sun, Yingyue Zhang, Jing Shi, Lu-Jun Liang
Journal: JACS Au
Doi: doi/10.1021/jacsau.5c00067
Products & Services: Protein Electrophoresis and Western   
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants
Authors: Shouya Feng, Matthew C Wierzbowski, Katja Hrovat-Schaale, Andreas Dumortier, Yaoyuan Zhang, Maria Zyulina, Paul J Baker, Thomas Reygaerts, Annemarie Steiner, Dominic De Nardo, Dhanya Lakshmi Narayanan, Florian Milhavet, Alberto Pinzon-Charry, Juan Ignacio Arostegui, Raju P Khubchandani, Matthias Geyer, Guilaine Boursier, Seth L Masters
Journal: nature immunology
PubMed ID: 39930093
Doi: 10.1038/s41590-025-02088-9
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GLP1 alleviates oleic acid-propelled lipocalin-2 generation by tumor-infiltrating CD8+ T cells to reduce polymorphonuclear MDSC recruitment and enhances viral immunotherapy in pancreatic cancer
Authors: Jingyi Wu, Peng Qian, Yifeng Han, Chuning Xu, Mao Xia, Ping Zhan, Jiwu Wei, Jie Dong
Journal: Cellular & molecular immunology
PubMed ID: 39910336
Doi: 10.1038/s41423-025-01260-3
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SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
Authors: Alexander J Garvin, Alexander J Lanz, George E Ronson, Matthew J W Mackintosh, Katarzyna Starowicz, Alexandra K Walker, Yara Aghabi, Hannah MacKay, Ruth M Densham, Jai S Bhachoo, Aneika C Leney, Joanna R Morris
Journal: Mol Cell
PubMed ID: 40054443
Doi: 10.1016/j.molcel.2025.02.004
The OsIAA3-OsARF16-OsBUL1 auxin signaling module regulates grain size in rice
Authors: Fengjun Xian, Shuya Liu, Jishuai Huang, Bin Xie, Lin Zhu, Qiannan Zhang, Chen Lv, Yimeng Xu, Xinrong Zhang, Jun Hu
Journal: Plant Physiol
PubMed ID: 40156155
Doi: 10.1093/plphys/kiaf122
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ER nests are specialized ER subdomains in Arabidopsis where peroxisomes and lipid droplets form
Authors: Zachary J Wright , Nathan E Tharp , Bonnie Bartel
Journal: Developmental Cell
Doi: 10.1016/j.devcel.2025.03.005
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Active- and Allosteric-Site Cyclic Peptide Inhibitors of Secreted M. tuberculosis Chorismate Mutase
Authors: Renier H P van Neer, Patricia K Dranchak, Mahesh Aitha, Lijun Liu, Emma K Carlson, Isabella E Jacobsen, Kevin Battaile, Yuhong Fang, Dingyin Tao, Ganesha Rai, Janak Padia, Scott Lovell, Hiroaki Suga, James Inglese
Journal: ACS Infectious Diseases
PubMed ID: 39903128
Doi: 10.1021/acsinfecdis.4c00798
Products & Services: Peptide Synthesis   Plasmid DNA Preparation   
Potential role of TRAF2 in pulmonary hypertension in broiler chickens and preparation and specificity analysis of its polyclonal antibody
Authors: Wen Peng, Gen Wan, Sufang Cheng, Guyue Li, Liling Liu, Juan Chen, Pei Liu, Xiaoquan Guo, Xiaona Gao, Gaofeng Cai, Zhanhong Zheng, Ping Liu
Journal: Int J Biol Macromol
PubMed ID: 39798767
Doi: doi.org/10.1016/j.ijbiomac.2025.139741
Products & Services: Protein Electrophoresis and Western   
Structural recognition and stabilization of tyrosine hydroxylase by the J-domain protein DNAJC12
Authors: Mary Dayne S Tai, Lissette Ochoa, Marte I Flydal, Lorea Velasco-Carneros, Jimena Muntaner, César Santiago, Gloria Gamiz-Arco, Fernando Moro, Kunwar Jung-Kc, David Gil-Cantero, Miguel Marcilla, Juha P Kallio, Arturo Muga, José María Valpuesta, Jorge Cuéllar, Aurora Martinez
Journal: Nature Communications
PubMed ID: 40113792
Doi: 10.1038/s41467-025-57733-6
Mimicry of molecular glues using dual covalent chimeras
Authors: Eden Kapcan, Karolina Krygier, Maya da Luz, Nickolas J Serniuck, Ali Zhang, Jonathan Bramson, Anthony F Rullo
Journal: Nature Communications
PubMed ID: 40128528
Doi: 10.1038/s41467-025-58083-z
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Conformational reorganization and phase separation drive hyper-editing of ADR-2-ADBP-1 complex
Authors: Jianqiang Mu, Cang Wu, Kaiming Xu, Xingang Liu, Yajuan Fu, Zhen Zhang, Jingwei Yu, Chenyang Xue, Zi Wang, Xinmeng Chen, Yanhong Chen, Guangshuo Ou, Zhongmin Liu
Journal: Nucleic Acids Res
PubMed ID: 40037706
Doi: 10.1093/nar/gkaf148
Resilient Membranized Coacervates Formed through Spontaneous Wrapping of Heat-Destabilized Lipid Bilayers around Coacervate Droplets
Authors: Sadaf Javed, Evan Spruijt
Journal: Advanced Science
PubMed ID: 40116289
Doi: 10.1002/advs.202412312
Bacterial Hachiman complex executes DNA cleavage for antiphage defense
Authors: Yongqing Cui, Zhikang Dai, Yufei Ouyang, Chunyang Fu, Yanjing Wang, Xueting Chen, Kaiyue Yang, Shuyue Zheng, Wenwen Wang, Pan Tao, Zeyuan Guan, Tingting Zou
Journal: Nature Communications
PubMed ID: 40097437
Doi: 10.1038/s41467-025-57851-1
Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β
Authors: Tyler M Weaver, Benjamin J Ryan, Spencer H Thompson, Adil S Hussen, Jonah J Spencer, Zhen Xu, Nicholas J Schnicker, Bret D Freudenthal
Journal: Nature Communications
PubMed ID: 40097433
Doi: 10.1038/s41467-025-57915-2
Products & Services: Codon Optimization   
Structural dynamics of DNA unwinding by a replicative helicase
Authors: Taha Shahid, Ammar U Danazumi, Muhammad Tehseen, Lubna Alhudhali, Alice R Clark, Christos G Savva, Samir M Hamdan, Alfredo De Biasio
Journal: Nature
PubMed ID: 40108462
Doi: 10.1038/s41586-025-08766-w
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Plant essential oil targets TRPV3 for skin renewal and structural mechanism of action
Authors: Yang Li, Xuteng Lu, Xufeng Cheng, Keyu Xia, Junyan Hu, Peiyu Wang, Peiyuan Pang, Bomin Gao, Demeng Sun, Zhuzhen Zhang, Dongdong Li, Zengqin Deng, Changlin Tian, Chang Xie, Jing Yao
Journal: Nature Communications
PubMed ID: 40108208
Doi: 10.1038/s41467-025-58033-9
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FLT1 and other candidate fetal haemoglobin modifying loci in sickle cell disease in African ancestries
Authors: Ambroise Wonkam, Kevin Esoh, Rachel M Levine, Valentina Josiane Ngo Bitoungui, Khuthala Mnika, Nikitha Nimmagadda, Erin A D Dempsey, Siana Nkya, Raphael Z Sangeda, Victoria Nembaware, Jack Morrice, Fujr Osman, Michael A Beer, Julie Makani, Nicola Mulder, Guillaume Lettre, Martin H Steinberg, Rachel Latanich, James F Casella, Daiana Drehmer, Dan E Arking, Emile R Chimusa, Jonathan S Yen, Gregory A Newby, Stylianos E Antonarakis
Journal: Nature Communications
PubMed ID: 40025045
Doi: 10.1038/s41467-025-57413-5
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Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits
Authors: Loϊc Binan, Aiping Jiang, Serwah A Danquah, Vera Valakh, Brooke Simonton, Jon Bezney, Robert T Manguso, Kathleen B Yates, Ralda Nehme, Brian Cleary, Samouil L Farhi
Journal: Cell
PubMed ID: 40081369
Doi: 10.1016/j.cell.2025.02.012
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Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity
Authors: Liora S Katz, Emira J Visser, Kathrin F Plitzko, Marloes A M Pennings, Peter J Cossar, Isabelle L Tse, Markus Kaiser, Luc Brunsveld, Christian Ottmann, Donald K Scott
Journal: Nature Communications
PubMed ID: 40025013
Doi: 10.1038/s41467-025-57241-7
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Structures of complete HIV-1 TAR RNA portray a dynamic platform poised for protein binding and structural remodeling
Authors: Charles Bou-Nader, Katie A Link, Krishna C Suddala, Jay R Knutson, Jinwei Zhang
Journal: Nature Communications
PubMed ID: 40050622
Doi: 10.1038/s41467-025-57519-w
Products & Services: Peptide Synthesis   
Blockade of ZMIZ1-GATA4 Axis Regulation Restores Youthfulness to Aged Cartilage
Authors: Jiho Nam, Hyunmin Woo, Jihye Yang, Seok Jung Kim, Kwang Pyo Lee, Ji Hoon Yu, Tae Joo Park, Seong-Il Eyun, Siyoung Yang
Journal: Advanced Science
PubMed ID: 40040621
Doi: 10.1002/advs.202404311
Products & Services: Chemicals   
Enhanced SIRT3 expression restores mitochondrial quality control mechanism to reverse osteogenic impairment in type 2 diabetes mellitus
Authors: Yansi Xian, Bin Liu, Tao Shen, Lin Yang, Rui Peng, Hongdou Shen, Xueying An, Yutian Wang, Yu Ben, Qing Jiang, Baosheng Guo
Journal: Bone Res
PubMed ID: 40025004
Doi: 10.1038/s41413-024-00399-5
Products & Services: Protein and Antibody Isolation   
Structure-Guided Development of Chemically Tailored Peptide Binders of RNF43/ZNRF3 to Enable Versatile Design of Membrane Protein-Targeting PROTACs
Authors: Jibin Cui , Qingyun Zheng , Yicheng Weng , Xiaoguo Zhai , Zhen Su , Yunxiang Du , Xiaoxiong Wei , Yuanyuan Yu , Qian Qu , Man Pan
Journal: Analytical Chemistry
PubMed ID: 40000409
Doi: doi.org/10.1002/anie.202501488
Products & Services: Codon Optimization   Gene Synthesis   
Rational Design Assisted by Evolutionary Engineering Allows (De)Construction and Optimization of Complex Phenotypes in Pseudomonas putida KT2440
Authors: Blas Blázquez, Juan Nogales
Journal: Microbial biotechnology
PubMed ID: 40126873
Doi: 10.1111/1751-7915.70132
Products & Services: Gene Synthesis   
Enhancing Prime Editing Efficiency Through Modulation of Methylation on the Newly Synthesized DNA Strand and Prolonged Expression
Authors: Xiaosong Han, Xianghua Xu, Youcai Xiong, Guangxing Zhao, Ruigao He, Yinyu Su, Sheng Li, Changzhi Zhao, Xiaoning Xi, Yunxia Zhao, Xuewen Xu, Shengsong Xie, Heng Wang, Xinyun Li, Shuhong Zhao, Jinxue Ruan
Journal: Advanced Science
PubMed ID: 40051369
Doi: 10.1002/advs.202417790
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Epstein-Barr virus infection promotes T cell dysregulation in a humanized mouse model of multiple sclerosis
Authors: Jessica R Allanach, Naomi M Fettig, Blair K Hardman, Ariel R Rosen, Vina Fan, Cynthia Chung, Erin J Goldberg, Zachary J Morse, Iryna Shanina, Galina Vorobeychik, Lisa C Osborne, Marc S Horwitz
Journal: SCIENCE ADVANCES
PubMed ID: 40043135
Doi: 10.1126/sciadv.adu5110
Products & Services: Peptide Synthesis   
Immunomodulatory role of the stem cell circadian clock in muscle repair
Authors: Pei Zhu, Eric M Pfrender, Adam W T Steffeck, Colleen R Reczek, Yalu Zhou, Abhishek Vijay Thakkar, Neha R Gupta, Ariana Kupai, Amber Willbanks, Richard L Lieber, Ishan Roy, Navdeep S Chandel, Clara B Peek
Journal: SCIENCE ADVANCES
PubMed ID: 40043110
Doi: 10.1126/sciadv.adq8538
Products & Services: Gene Synthesis   
Integration of multi-omics data accelerates molecular analysis of common wheat traits
Authors: Ning Zhang, Li Tang, Songgang Li, Lu Liu, Mengjuan Gao, Sisheng Wang, Daiying Chen, Yichao Zhao, Ruiqing Zheng, Armin Soleymaniniya, Lingran Zhang, Wenkang Wang, Xia Yang, Yan Ren, Congwei Sun, Mathias Wilhelm, Daowen Wang, Min Li, Feng Chen
Journal: Nature Communications
PubMed ID: 40038279
Doi: 10.1038/s41467-025-57550-x
Products & Services: Molecular Biology Tools   
Elevated NAD+ drives Sir2A-mediated GCβ deacetylation and OES localization for Plasmodium ookinete gliding and mosquito infection
Authors: Yang Shi, Lin Wan, Mengmeng Jiao, Chuan-Qi Zhong, Huiting Cui, Jing Yuan
Journal: Nature Communications
PubMed ID: 40050296
Doi: 10.1038/s41467-025-57517-y
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A globular protein exhibits rare phase behavior and forms chemically regulated orthogonal condensates in cells
Authors: Jinglei Nie, Xinyi Zhang, Zhijuan Hu, Wei Wang, Martin A Schroer, Jie Ren, Dmitri Svergun, Anyang Chen, Peiguo Yang, An-Ping Zeng
Journal: Nature Communications
PubMed ID: 40069234
Doi: 10.1038/s41467-025-57886-4
Products & Services: Gene Synthesis   
Soft-matter-induced orderings in a solid-state van der Waals heterostructure
Authors: Kai Zhao, Baojuan Dong, Yuang Wang, Xiaoxue Fan, Qi Wang, Zhiren Xiong, Jing Zhang, Jinkun He, Kaining Yang, Minru Qi, Chengbing Qin, Tongyao Zhang, Maolin Chen, Hanwen Wang, Jianqi Huang, Kai Liu, Hanwei Huang, Kenji Watanabe, Takashi Taniguchi, Yaning Wang, Xixiang Zhang, Juehan Yang, Zhenwen Huang, Yongjun Li, Zhongming Wei, Jing Zhang, Shuoxing Jiang, Zheng Vitto Han, Funan Liu
Journal: Nature Communications
PubMed ID: 40064923
Doi: 10.1038/s41467-025-57690-0
Structural basis for the allosteric activation of Lon by the heat shock protein LarA
Authors: Hsiu-Jung Wang, Yun-Erh Kuan, Meng-Ru Ho, Chung-I Chang
Journal: Nature Communications
PubMed ID: 40044692
Doi: 10.1038/s41467-025-57482-6
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Selective promotion of sensory innervation-mediated immunoregulation for tissue repair
Authors: Kaicheng Xu, Kaile Wu, Liang Chen, Yubin Zhao, Hengyuan Li, Nong Lin, Zhaoming Ye, Jianbin Xu, Donghua Huang, Xin Huang
Journal: SCIENCE ADVANCES
PubMed ID: 40117376
Doi: 10.1126/sciadv.ads9581
Functional and antigenic landscape of the Nipah virus receptor-binding protein
Authors: Brendan B Larsen, Teagan McMahon, Jack T Brown, Zhaoqian Wang, Caelan E Radford, James E Crowe Jr, David Veesler, Jesse D Bloom
Journal: Cell
PubMed ID: 38659959
Doi: 10.1101/2024.04.17.589977
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Cryo-EM Analysis of a Tri-Heme Cytochrome-Associated RC-LH1 Complex from the Marine Photoheterotrophic Bacterium Dinoroseobacter Shibae
Authors: Weiwei Wang, Yanting Liu, Jiayi Gu, Shaoya An, Cheng Ma, Haichun Gao, Nianzhi Jiao, Jian-Ren Shen, John Thomas Beatty, Michal Koblížek, Xing Zhang, Qiang Zheng, Jing-Hua Chen
Journal: Advanced Science
PubMed ID: 40112203
Doi: 10.1002/advs.202413456
Products & Services: Protein Electrophoresis and Western   
Overlapping and separable activities of BRA-2 and HIM-17 promote occurrence and regulation of pairing and synapsis during Caenorhabditis elegans meiosis
Authors: Jitka Blazickova, Shalini Trivedi, Richard Bowman, Sowmya Sivakumar Geetha, Silma Subah, Michelle Scuzzarella, Alexander Chang, Uma R Chandran, Judith L Yanowitz, Sarit Smolikove, Verena Jantsch, Monique Zetka, Nicola Silva
Journal: Nature Communications
PubMed ID: 40082424
Doi: 10.1038/s41467-025-57862-y
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Oral delivery of therapeutic proteins by engineered bacterial type zero secretion system
Authors: Xu Gong , Shan Liu , Bozhang Xia , Yichen Wan , Shuyi Zhang , Baoyan Zhang , Zehao Wang , Junge Chen , Fei Xiao , Xing-Jie Liang , Yun Yang
Journal: Nat Commun
PubMed ID: 39984501
Doi: 10.1038/s41467-025-57153-6
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EXPERT expands prime editing efficiency and range of large fragment edits
Authors: Youcai Xiong , Yinyu Su , Ruigao He , Xiaosong Han , Sheng Li , Minghuan Liu , Xiaoning Xi , Zijia Liu , Heng Wang , Shengsong Xie , Xuewen Xu , Kui Li , Jifeng Zhang , Jie Xu , Xinyun Li , Shuhong Zhao , Jinxue Ruan
Journal: Nat Commun
PubMed ID: 39939583
Doi: 10.1038/s41467-025-56734-9
Products & Services: Gene Synthesis   
Self-assembly GSH response based Buforin IIb-Olaparib nanocombination synergistically promotes DNA damage for prostate cancer immunotherapy
Authors: Maosong Hu , Yuyu Zhu , Xinyi Tang , Jing Xu , Hanbin Ma , Zhihan Chen , Duo Chen , Wenyuan Wu , Xialin Chen , Rongrong He , Jing Zhou , Jinao Duan , Weiguo Chen , Hongyue Ma
Journal: Chemical Engineering Journal
Doi: 10.1016/j.cej.2025.160862
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Deciphering molecular specificity in MCL-1/BAK interaction and its implications for designing potent MCL-1 inhibitors
Authors: Hudie Wei, Haolan Wang, Shuang Xiang, Jiaqi Wang, Lingzhi Qu, Xiaojuan Chen, Ming Guo, Xiaoyun Lu, Yongheng Chen
Journal: Cell Death Differ
PubMed ID: 39901037
Doi: 10.1038/s41418-025-01454-2
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Expanding Cas12a Activity Control with an RNA G-Quadruplex at the 5′ end of CRISPR RNA
Authors: Wenjuan Huang, Jiaqi Wang, Cheng Wang, Yuanfang Liu, Wentao Li, Qiaozhen Chen, Junqiu Zhai, Zhenyang Xiang, Chaoxing Liu
Journal: Advanced Science
PubMed ID: 39721016
Doi: 10.1002/advs.202411305
Products & Services: Catalog Gene Editing   
Activation of the bacterial defenseassociated sirtuin system
Authors: Kaixiang Zhu, Kun Shang, Linyue Wang, Xia Yu, Lei Hua, Weihe Zhang, Bo Qin, Jia Wang, Xiaopan Gao, Hongtao Zhu, Sheng Cui
Journal: Communications Biology
PubMed ID: 39994439
Doi: doi.org/10.1038/s42003-025-07743-3
Products & Services: Gene Synthesis   
Structures of HCoV-OC43 HR1 Domain in Complex with Cognate HR2 or Analogue EK1 Peptide
Authors: Xiuxiu He, Huanzhen Liu, Guang Yang, Lei Yan
Journal: Viruses-Basel
PubMed ID: 40143271
Doi: 10.3390/v17030343
Products & Services: Peptide Synthesis   
Bioengineered protein nanocarrier facilitating siRNA escape from lysosomes for targeted RNAi therapy in glioblastoma
Authors: Yiliang Jin, Baoli Zhang, Jianru Li, Zhenxi Guo, Chen Zhang, Xuehui Chen, Long Ma, Zhuoran Wang, Haiyin Yang, Yong Li, Yuhua Weng, Yuanyu Huang, Xiyun Yan, Kelong Fan
Journal: SCIENCE ADVANCES
PubMed ID: 39970222
Doi: 10.1126/sciadv.adr9266
Products & Services: Gene Synthesis   
Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple negative breast cancer
Authors: Xue Yang, Xiuquan Ma, Tianyue Zhao, David R Croucher, Elizabeth V Nguyen, Kimberley C Clark, Changyuan Hu, Sharissa L Latham, Charles Bayly-Jones, Bao V Nguyen, Srikanth Budnar, Sung-Young Shin, Lan K Nguyen, Thomas R Cotton, Anderly C Chüeh, Terry C C Lim Kam Sian, Margaret M Stratton, Andrew M Ellisdon, Roger J Daly
Journal: Nature Communications
PubMed ID: 39984440
Doi: 10.1038/s41467-025-57046-8
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CK2B Induces CD8+ T-Cell Exhaustion through HDAC8-Mediated Epigenetic Reprogramming to Limit the Efficacy of Anti-PD-1 Therapy in Non-Small-Cell Lung Cancer
Authors: Shaochuan Liu, Shiya Ma, Gen Liu, Lingjie Hou, Yong Guan, Liang Liu, Yuan Meng, Wenwen Yu, Ting Liu, Li Zhou, Zhiyong Yuan, Shuju Pang, Siyuan Zhang, Junyi Li, Xiubao Ren, Qian Sun
Journal: Advanced Science
PubMed ID: 40013761
Doi: 10.1002/advs.202411053
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RH3 enhances antiviral defense by facilitating small RNA loading into Argonaute 2 at endoplasmic reticulum–chloroplast membrane contact sites
Authors: Juan Huang, Juan Du, Yan Liu, Lu Lu, Yanzhuo Xu, Jianfei Shi, Qing Liu, Qi Li, Yang Liu, Yaqiu Chen, Meng Du, Yiming Zhao, Liangxiao Huo, Weiran Wang, Chenxi Ding, Liya Wei, Jianguo Wu, Yao-Wu Yuan, Jinfeng Chen, Ruixi Li, Feng Cui, Xiaoming Zhang
Journal: Nature Communications
PubMed ID: 40000658
Doi: 10.1038/s41467-025-57296-6
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The TaCLE24b peptide signaling cascade modulates lateral root development and drought tolerance in wheat
Authors: Wen Yang, Man Feng, Kuohai Yu, Jie Cao, Guangxian Cui, Yumei Zhang, Huiru Peng, Yingyin Yao, Zhaorong Hu, Zhongfu Ni, Feng Qin, Fuminori Takahashi, Qixin Sun, Mingming Xin
Journal: Nature Communications
PubMed ID: 40000659
Doi: 10.1038/s41467-025-57291-x
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Evaluation of Cas13d as a tool for genetic interaction mapping
Authors: Ghanem El Kassem, Jasmine Hillmer, Michael Boettcher
Journal: Nature Communications
PubMed ID: 39952934
Doi: 10.1038/s41467-025-56747-4
Products & Services: Gene Fragments   
Design of CoQ10 crops based on evolutionary history
Authors: Jing-Jing Xu, Yuan Lei, Xiao-Fan Zhang, Jian-Xu Li, Qiupeng Lin, Xiang-Dong Wu, Yu-Guo Jiang, Wenyi Zhang, Runtong Qian, Shu-Yi Xiong, Kuo Tan, Yu Jia, Qiang Zhou, Yan Jiang, Hang Fan, Yan-Bo Huang, Ling-Jian Wang, Ji-Yun Liu, Yu Kong, Qing Zhao, Lei Yang, Jinxing Liu, Yong-Hong Hu, Shuai Zhan, Caixia Gao, Xiao-Ya Chen
Journal: Cell
PubMed ID: 39952246
Doi: 10.1016/j.cell.2025.01.023
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Double antibody sandwich ELISA based on rabbit monoclonal antibody targeting gD protein for the detection of bovine herpesvirus 1
Authors: Qiang Liu, Xiaoxia Niu, Lingling Jiang, Gang Zhang, Pu Wang, Sinong Zhang, Weifeng Gao, Huichen Guo, Yujiong Wang, Yong Li
Journal: Int J Biol Macromol
PubMed ID: 39929469
Doi: 10.1016/j.ijbiomac.2025.140671
Products & Services: Gene Synthesis   
DNA tetrahedron nanomedicine for enhanced antitumor and antimetastatic effect through the amplification of mitochondrial oxidative stress
Authors: Zixuan Chen , Zhaoyan Tian , Yafeng Wu , Songqin Liu
Journal: Acta Biomater
PubMed ID: 39922515
Doi: 10.1016/j.actbio.2025.02.011
Products & Services: Protein and Antibody Isolation   
Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK
Authors: Chang Peng, Haowen Jiang, Liya Jing, Wenhua Yang, Xiaotong Guan, Hanlin Wang, Sike Yu, Yutang Cao, Min Wang, Huan Ma, Zan Lv, Hongyu Gu, Chunmei Xia, Xiaozhen Guo, Bin Sun, Aili Wang, Cen Xie, Wenbiao Wu, Luyiyi Lu, Jiayi Song, Saifei Lei, Rui Wu, Yi Zang, Erjiang Tang, Jia Li
Journal: Nat Commun
PubMed ID: 39966410
Doi: 10.1038/s41467-025-57044-w
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PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins
Authors: Christopher R Horne, Toby A Dite, Samuel N Young, Lucy J Mather, Laura F Dagley, Jared L Johnson, Tomer M Yaron-Barir, Emily M Huntsman, Leonard A Daly, Dominic P Byrne, Antonia L Cadell, Boaz H Ng, Jumana Yousef, Dylan H Multari, Lianju Shen, Luke M McAloon, Gerard Manning, Mark A Febbraio, Anthony R Means, Lewis C Cantley, Maria C Tanzer, David R Croucher, Claire E Eyers, Patrick A Eyers, John W Scott, James M Murphy
Journal: Proc Natl Acad Sci U S A
PubMed ID: 39964718
Doi: 10.1073/pnas.2420961122
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Enhancing mRNA translation efficiency by introducing sequence optimized AU-rich elements in 3′ UTR via HuR anchorage
Authors: Xinghuan Ma , Sujia Liu , Bangda Fan , Danni Jin , Lei Miao , Lin Liu , Shubo Du , Jiaqi Lin
Journal: Mol Ther Nucleic Acids
PubMed ID: 40125272
Doi: doi.org/10.1016/j.omtn.2025.102485
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Controllable intein splicing and N-terminal cleavage at mesophilic temperatures
Authors: Taylor A McNeal, Joel Weinberger, Geraldy L S Liman, Tia M Ariagno, David W Wood, Thomas J Santangelo, Christopher W Lennon
Journal: Front Bioeng Biotechnol
PubMed ID: 39991137
Doi: 10.3389/fbioe.2025.1543573
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Structural and mechanistic insights into the activation of a short prokaryotic argonaute system from archaeon Sulfolobus islandicus
Authors: Zhikang Dai, Yu Chen, Zeyuan Guan, Xueting Chen, Keyi Tan, Kaiyue Yang, Xuhui Yan, Yidong Liu, Zhou Gong, Wenyuan Han, Tingting Zou
Journal: Nucleic Acids Res
PubMed ID: 39898546
Doi: 10.1093/nar/gkaf059
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Structure of the tilapia lake virus nucleoprotein bound to RNA
Authors: Benoît Arragain, Martin Pelosse, Karine Huard, Stephen Cusack
Journal: Nucleic Acids Res
PubMed ID: 39995042
Doi: 10.1093/nar/gkaf112
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Conserved immunomodulation and variation in host association by Xanthomonadales commensals in Arabidopsis root microbiota
Authors: Jana Ordon、Elke Logemann、Louis-Philippe Maier、Tak Lee、Eik Dahms、Anniek Oosterwijk、Jose Flores-Uribe、Shingo Miyauchi、Lucas Paoli、Sara Christina Stolze、Hirofumi Nakagami、Georg Felix、Ruben Garrido-Oter、Ka-Wai Ma 和 Paul Schulze-Lefert
Journal: Nat Plants
PubMed ID: 39972185
Doi: 10.1038/s41477-025-01918-w
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Genetic regulation of TERT splicing affects cancer risk by altering cellular longevity and replicative potential
Authors: Oscar Florez-Vargas, Michelle Ho, Maxwell H Hogshead, Brenen W Papenberg, Chia-Han Lee, Kaitlin Forsythe, Kristine Jones, Wen Luo, Kedest Teshome, Cornelis Blauwendraat, Kimberly J Billingsley, Mikhail Kolmogorov, Melissa Meredith, Benedict Paten, Raj Chari, Chi Zhang, John S Schneekloth, Mitchell J Machiela, Stephen J Chanock, Shahinaz M Gadalla, Sharon A Savage, Sam M Mbulaiteye, Ludmila Prokunina-Olsson
Journal: Nature Communications
PubMed ID: 39956830
Doi: 10.1038/s41467-025-56947-y
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Reversible ubiquitination conferred by domain shuffling controls paired NLR immune receptor complex homeostasis in plant immunity
Authors: Zhiyi Chen, Jianhua Huang, Jianyu Li, Frank L. H. Menke, Jonathan D. G. Jones & Hailong Guo
Journal: Nature Communications
Doi: 10.1038/s41467-025-57231-9
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Molecular determinants of cross-strain influenza A virus recognition by αβ T cell receptors
Authors: Sergio M Quiñones-Parra, Stephanie Gras, Thi H O Nguyen, Carine Farenc, Christopher Szeto, Louise C Rowntree, Priyanka Chaurasia, Sneha Sant, Adrianus C M Boon, Dhilshan Jayasinghe, Guus F Rimmelzwaan, Jan Petersen, Peter C Doherty, Adam P Uldrich, Dene R Littler, Jamie Rossjohn, Katherine Kedzierska
Journal: Science immunology
PubMed ID: 39919196
Doi: 10.1126/sciimmunol.adn3805
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Bacteria encode post-mortem protein catabolism that enables altruistic nutrient recycling
Authors: Savannah E R Gibson, Isabella Frost, Stephen J Hierons, Tessa Moses, Wilson C K Poon, Stuart A West, Martin J Cann
Journal: Nature Communications
PubMed ID: 39948360
Doi: 10.1038/s41467-025-56761-6
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CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair
Authors: Feng Li, Tianpeng Zhang, Aleem Syed, Amira Elbakry, Noella Holmer, Huy Nguyen, Sirisha Mukkavalli, Roger A Greenberg, Alan D D'Andrea
Journal: Nature Communications
PubMed ID: 39962076
Doi: 10.1038/s41467-025-56834-6
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Structural basis of ssDNA-guided NADase activation of prokaryotic SPARTA system
Authors: Rong Hu, Chenmin Guo, Xiaotian Liu, Yuanyi Lin, Zixin Yang, Zhixin Li, Ye Yang, Erman Ma, Yiyi Li, Jiyun Chen, Liang Liu
Journal: Nucleic Acids Res
PubMed ID: 39997222
Doi: 10.1093/nar/gkaf110
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RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer
Authors: Zachary Sethna, Pablo Guasp, Charlotte Reiche, Martina Milighetti, Nicholas Ceglia, Erin Patterson,on Jay Lihm, George Payne, Olga Lyudovyk, Luis A Rojas, Nan Pang, Akihiro Ohmoto, Masataka Amisaki, Abderezak Zebboudj, Zagaa Odgerel, Emmanuel M Bruno, Siqi Linsey Zhang, Charlotte Cheng, Yuval Elhanati, Evelyna Derhovanessian, Luisa Manning, Felicitas Müller, Ina Rhee, Mahesh Yad,av Taha Merghoub, Jedd D Wolchok, Olca Basturk, Mithat Gönen, Andrew S Epstein, Parisa Momtaz, Wungki Park, Ryan Sugarman, Anna M Varghese, Elizabeth Won, Avni Desai, Alice C Wei, Michael I D'Angelica, T Peter Kingham, Kevin C Soares, William R Jarnagin, Jeffrey Drebin, Eileen M O'Reilly, Ira Mellman, Ugur Sahin, Özlem Türeci, Benjamin D Greenbaum, Vinod P Balachandran
Journal: Nature
PubMed ID: 39972124
Doi: 10.1038/s41586-024-08508-4
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Cooperative nutrient scavenging is an evolutionary advantage in cancer
Authors: Gizem Guzelsoy, Setiembre D Elorza, Manon Ros, Logan T Schachtner, Makiko Hayashi, Spencer Hobson-Gutierrez, Parker Rundstrom, Julia S Brunner, Ray Pillai, William E Walkowicz, Lydia W S Finley, Maxime Deforet, Thales Papagiannakopoulos, Carlos Carmona-Fontaine
Journal: Nature
PubMed ID: 39972131
Doi: 10.1038/s41586-025-08588-w
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ABC transporter activity is affected by the size of lipid nanodiscs
Authors: Annabella Nouel Barreto, Luis G Cuello, Maria E Zoghbi
Journal: FEBS letters
PubMed ID: 39748569
Doi: 10.1002/1873-3468.15096
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Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells
Authors: Mélanie Uguen, Devan J Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M Szewczyk, Ka Yang, Yani Zhao, Michael A Stashko, Jacqueline L Norris-Drouin, Jarod M Waybright, Serap Beldar, Justin M Rectenwald, Angie L Mordant, Thomas S Webb, Laura E Herring, Cheryl H Arrowsmith, Suzanne Ackloo, Steven P Gygi, Robert K McGinty, Dalia Barsyte-Lovejoy, Pengda Liu, Levon Halabelian, Lindsey I James, Kenneth H Pearce, Stephen V Frye
Journal: Nature Communications
PubMed ID: 39994194
Doi: 10.1038/s41467-025-57005-3
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Dual functional POGases from bacteria encompassing broader O-glycanase and adhesin activities
Authors: Linjiao Zhou, Uriel Ortega-Rodriguez, Matthew J Flores, Yasuyuki Matsumoto, John Q Bettinger, Wells W Wu, Yaqin Zhang, Su-Ryun Kim, Thomas G Biel, Jordan D Pritts, Rong-Fong Shen, V Ashutosh Rao, Tongzhong Ju.
Journal: Nature Communications
PubMed ID: 40000644
Doi: 10.1038/s41467-025-57143-8
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Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates
Authors: Prakash Jadhav, Xueying Liang, Ahmadullah Ansari, Bin Tan, Haozhou Tan, Kan Li, Xiang Chi, Alexandra Ford, Francesc Xavier Ruiz, Eddy Arnold, Xufang Deng, Jun Wang
Journal: Nature Communications
PubMed ID: 39948104
Doi: 10.1038/s41467-025-56902-x
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Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ
Authors: Bing Wang, Nelly Said, Tarek Hilal, Mark Finazzo, Markus C Wahl, Irina Artsimovitch
Journal: Nature Communications
PubMed ID: 39952913
Doi: 10.1038/s41467-025-56824-8
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The CXCL8/MAPK/hnRNP-K axis enables susceptibility to infection by EV-D68, rhinovirus, and influenza virus in vitro
Authors: Qingran Yang, Haoran Guo, Huili Li, Zhaoxue Li, Fushun Ni, Zhongmei Wen, Kai Liu, Huihui Kong, Wei Wei
Journal: Nature Communications
PubMed ID: 39962077
Doi: 10.1038/s41467-025-57094-0
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Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies
Authors: Yan-Ruide Li, Ying Fang, Siyue Niu, Yichen Zhu, Yuning Chen, Zibai Lyu, Enbo Zhu, Yanxin Tian, Jie Huang, Valerie Rezek, Scott Kitchen, Tzung Hsiai, Jin J Zhou, Pin Wang, Wanxing Chai-Ho, Sunmin Park, Christopher S Seet, Caspian Oliai, Lili Yang
Journal: Nature Communications
PubMed ID: 39893165
Doi: 10.1038/s41467-025-56270-6
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Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses
Authors: Young-Jun Park, Chen Liu, Jimin Lee, Jack T Brown, Cheng-Bao Ma, Peng Liu, Risako Gen, Qing Xiong, Samantha K Zepeda, Cameron Stewart, Amin Addetia, Caroline J Craig, M Alejandra Tortorici, Abeer N Alshukairi, Tyler N Starr, Huan Yan, David Veesler
Journal: Cell
PubMed ID: 39922192
Doi: 10.1016/j.cell.2024.12.032
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Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350
Authors: M Gordon Joyce, Wei Bu, Wei-Hung Chen, Rebecca A Gillespie, Sarah F Andrews, Adam K Wheatley, Yaroslav Tsybovsky, Jaime L Jensen, Tyler Stephens, Madhu Prabhakaran, Brian E Fisher, Sandeep R Narpala, Meghna Bagchi, Adrian B McDermott, Gary J Nabel, Peter D Kwong, John R Mascola, Jeffrey I Cohen, Masaru Kanekiyo
Journal: Immunity
PubMed ID: 39909035
Doi: 10.1016/j.immuni.2025.01.010
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Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling
Authors: Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Persechino, Sripriya Murthy, Cesare Orlandi, Christian D Sadik, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, Nina Wettschureck
Journal: Nature Communications
PubMed ID: 39920161
Doi: 10.1038/s41467-025-56713-0
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Massively parallel variant-to-function mapping determines functional regulatory variants of non-small cell lung cancer
Authors: Congcong Chen, Yang Li, Yayun Gu, Qiqi Zhai, Songwei Guo, Jun Xiang, Yuan Xie, Mingxing An, Chenmeijie Li, Na Qin, Yanan Shi, Liu Yang, Jun Zhou, Xianfeng Xu, Ziye Xu, Kai Wang, Meng Zhu, Yue Jiang, Yuanlin He, Jing Xu, Rong Yin, Liang Chen, Lin Xu, Juncheng Dai, Guangfu Jin, Zhibin Hu, Cheng Wang, Hongxia Ma, Hongbing Shen
Journal: Nature Communications
PubMed ID: 39910069
Doi: 10.1038/s41467-025-56725-w
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Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses
Authors: Cheng-Bao Ma, Chen Liu, Young-Jun Park, Jingjing Tang, Jing Chen, Qing Xiong, Jimin Lee, Cameron Stewart, Daniel Asarnow, Jack Brown, M Alejandra Tortorici, Xiao Yang, Ye-Hui Sun, Yuan-Mei Chen, Xiao Yu, Jun-Yu Si, Peng Liu, Fei Tong, Mei-Ling Huang, Jing Li, Zheng-Li Shi, Zengqin Deng, David Veesler, Huan Yan
Journal: Cell
PubMed ID: 39922191
Doi: 10.1016/j.cell.2024.12.031
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Distinct immunogenicity outcomes of DNA vaccines encoding malaria transmission-blocking vaccine target antigens Pfs230D1M and Pvs230D1
Authors: Yi Cao , Maisa da Silva Araujo , Cynthia G Lorang , Najara Akira Costa Dos Santos , Abhai Tripathi , Joseph Vinetz , Nirbhay Kumar
Journal: Vaccine
PubMed ID: 39787798
Doi: 10.1016/j.vaccine.2024.126696
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Establishment of an indirect ELISA method for detecting bovine coronavirus antibodies based on N protein
Authors: Qiang Liu , Xiaoxia Niu , Lingling Jiang , Gang Zhang , Pu Wang , Sinong Zhang , Weifeng Gao , Huichen Guo, Yujiong Wang and Yong Li
Journal: Frontiers in Veterinary Science
Doi: 10.3389/fvets.2025.1530870
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In vitro reconstitution of meiotic DNA double-strand-break formation
Authors: Xinzhe Tang , Zetao Hu , Jian Ding , Meixia Wu , Pin Guan , Yawei Song , Yue Yin , Wei Wu , Jinbiao Ma , Ying Huang , Ming-Han Tong
Journal: Nature
PubMed ID: 39972125
Doi: doi.org/10.1038/s41586-024-08551-1
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Identifying Exifone as a Dual-Target Agent Targeting Both SARS-CoV-2 3CL Protease and the ACE2/S-RBD Interaction Among Clinical Polyphenolic Compounds
Authors: Jiani Lu、Yan Tang、Hongtao Li、Xixiang Chen、Pengcheng Qin、Jianrong Xu、Weihua Li 和 Lili Chen
Journal: International Journal of Molecular Sciences
Doi: doi.org/10.3390/ijms26052243
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Polyamine-Depleting Hydrogen-Bond Organic Frameworks Unleash Dendritic Cell and T Cell Vigor for Targeted CRISPR/Cas-Assisted Cancer Immunotherapy
Authors: Yongchun Pan, Fei Zeng, Xiaowei Luan, Guanzhong He, Shurong Qin, Qianglan Lu, Bangshun He, Xin Han, Yujun Song
Journal: Adv Mater
PubMed ID: 39972681
Doi: 10.1002/adma.202411886
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A truncated pre-F protein mRNA vaccine elicits an enhanced immune response and protection against respiratory syncytial virus
Authors: Min Lin, Yifan Yin, Xiaomeng Zhao, Chen Wang, Xueqing Zhu, Letao Zhan, Li Chen, Siling Wang, Xue Lin, Jun Zhang, Ningshao Xia, Zizheng Zheng
Journal: Nat Commun
PubMed ID: 39910047
Doi: 10.1038/s41467-025-56302-1
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Sequence Context-Agnostic TadA-Derived Cytosine Base Editors for Genome-Wide Editing in Zebrafish
Authors: Shaohui Zheng 1 2, Yang Liu 1 2, Xinxin Xia 1 2, Jiawang Xiao 1 2, Hui Ma 3, Xuanyao Yuan 1 2, Yan Zhang 1 2, Zixi Chen 1 2, Guangcong Peng 1 2, Wenyuan Li 4, Ji-Feng Fei 3 5 6, Yanmei Liu
Journal: Advanced Science
PubMed ID: 39960330
Doi: 10.1002/advs.202411478
Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration.
Authors: Qiyu Tang, Keyi Tang, Greg R Markby, Maciej Parys, Kanchan Phadwal, Vicky E MacRae, Brendan M Corcoran
Journal: Autophagy
PubMed ID: 39988732
Doi: 10.1080/15548627.2025.2469315
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Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers
Authors: Kai Li, Xuan Yu, Yanteng Xu, Haixia Wang, Zheng Liu, Chong Wu, Xing Luo, Jiancheng Xu, Youqiang Fang, Enguo Ju, Shixian Lv, Hon Fai Chan, Yeh-Hsing Lao, Weiling He, Yu Tao, Mingqiang Li
Journal: Nature Communications
PubMed ID: 39952937
Doi: 10.1038/s41467-025-56407-7
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Pan-Variant SARS-CoV-2 Vaccines Induce Protective Immunity by Targeting Conserved Epitopes
Authors: Masaud Shah, Sung Ung Moon, Ji-Yon Shin, Ji-Hye Choi, Doyoon Kim, Hyun Goo Woo
Journal: Advanced Science
PubMed ID: 40014015
Doi: 10.1002/advs.202409919
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Co-translational protein aggregation and ribosome stalling as a broad-spectrum antibacterial mechanism
Authors: Laleh Khodaparast, Ladan Khodaparast, Ramon Duran-Romaña, Guiqin Wu, Bert Houben, Wouter Duverger, Matthias De Vleeschouwer, Katerina Konstantoulea, Fleur Nysen, Thomas Schalck, Daniel J Curwen, Lisandra L Martin, Sebastien Carpentier, Bernard Scorneaux, Jan Michiels, Joost Schymkowitz, Frederic Rousseau
Journal: Nature Communications
PubMed ID: 39939597
Doi: 10.1038/s41467-025-56873-z
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Alternatively spliced NFKB1 transcripts enriched in Andean Aymara modulate inflammation, HIF and hemoglobin
Authors: Jihyun Song, Seonggyun Han, Ricardo Amaru, Lucie Lanikova, Teddy Quispe, Dongwook Kim, Jacob E Crawford, Soo Jin Kim, Younghee Lee, Josef T Prchal
Journal: Nature Communications
PubMed ID: 39971917
Doi: 10.1038/s41467-025-56848-0
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Proteasomes accumulate in the plant apoplast where they participate in microbe-associated molecular pattern (MAMP)-triggered pathogen defense
Authors: Hana Zand Karimi, Kuo-En Chen, Marilee Karinshak, Xilin Gu, Jason K Sello, Richard D Vierstra
Journal: Nature Communications
PubMed ID: 39952938
Doi: 10.1038/s41467-025-56594-3
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Antibody prophylaxis may mask subclinical SIV infections in macaques
Authors: Christopher A Gonelli, Hannah A D King, SungYoul Ko, Christine M Fennessey, Nami Iwamoto, Rosemarie D Mason, Ashley Heimann, Dillon R Flebbe, John-Paul Todd, Kathryn E Foulds, Brandon F Keele, Jeffrey D Lifson, Richard A Koup, Mario Roederer.
Journal: Nature
PubMed ID: 39910294
Doi: 10.1038/s41586-024-08500-y
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Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I
Authors: Bryan Neumann, Stephen McCarthy, Shane Gonen
Journal: Nature Communications
PubMed ID: 39920100
Doi: 10.1038/s41467-024-55764-z
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