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The sequestration mechanism as a generalizable approach to improve the sensitivity of biosensors and bioassays

Authors: Alejandro Chamorro-Garcia , Claudio Parolo , Gabriel Ortega , Andrea Idili , Joshua Green , Francesco Ricci , Kevin W Plaxco

Journal: Chem Sci

PubMed ID: 36349092

Doi: 10.1039/d2sc03901j

Products & Services: Monoclonal Antibody Services

Lentiviral vector mediated gene therapy for type I Dent disease ameliorates Dent disease-like phenotypes for three months in ClC-5 null mice

Authors: Manish Kumar Yadav , Kyung Whan Yoo , Anthony Atala , Baisong Lu

Journal: Mol Ther Methods Clin Dev

PubMed ID: 36284768

Doi: 10.1016/j.omtm.2022.09.009

Products & Services: Gene Synthesis

Cross-reactivity between vaccine antigens from the chitin deacetylase protein family improves survival in a mouse model of cryptococcosis

Authors: Maureen M Hester, Lorena V N Oliveira, Ruiying Wang, Zhongming Mou, Diana Lourenco, Gary R Ostroff, Charles A Specht, Stuart M Levitz

Journal: Front Immunol

PubMed ID: 36248898

Doi: 10.3389/fimmu.2022.1015586

Products & Services: Bacterial Expression

Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery

Authors: Ferdinando M Milazzo, Antonio Chaves-Sanjuan, Olga Minenkova, Daniela Santapaola, Anna M Anastasi, Gianfranco Battistuzzi, Caterina Chiapparino, Antonio Rosi, Emilio Merlo Pich, Claudio Albertoni, Emanuele Marra, Laura Luberto, Cécile Viollet, Luigi G Spagnoli, Anna Riccio, Antonio Rossi, M Gabriella Santoro, Federico Ballabio, Cristina Paissoni, Carlo Camilloni, Martino Bolognesi, Rita De Santis

Journal: Mol Ther

PubMed ID: 36114671

Doi: 10.1016/j.ymthe.2022.09.010

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Structural characterization of SARS-CoV-2 dimeric ORF9b reveals potential fold-switching trigger mechanism

Authors: Xiyue Jin, Xue Sun, Yan Chai, Yu Bai, Ying Li, Tianjiao Hao, Jianxun Qi, Hao Song, Catherine C L Wong, George F Gao

Journal: Sci China Life Sci

PubMed ID: 36184694

Doi: 10.1007/s11427-022-2168-8

Products & Services: Plasmid DNA Preparation

Oral or intranasal immunization with recombinant Lactobacillus plantarum displaying head domain of Swine Influenza A virus hemagglutinin protects mice from H1N1 virus

Authors: Yufei Zhang, Li Yang, Jiali Zhang, Kun Huang, Xiaomei Sun, Ying Yang, Ting Wang, Qiang Zhang, Zhong Zou, Meilin Jin

Journal: Microb Cell Fact

PubMed ID: 36085207

Doi: 10.1186/s12934-022-01911-4

Products & Services: Plasmid DNA Preparation

Comparative transcriptome analysis of longissimus dorsi tissues with different intramuscular fat contents from Guangling donkeys

Authors: Wufeng Li, Lixia Qiu, Jiawei Guan, Yutong Sun, Jingwei Zhao, Min Du

Journal: BMC Genomics

PubMed ID: 36085018

Doi: 10.1186/s12864-022-08857-2

Products & Services: Molecular Biology Tools

Computer vision enabled funnel adapted sensing tube (FAST) for power-free and pipette-free nucleic acid detection

Authors: Mengdi Bao, Shuhuan Zhang, Chad Ten Pas, Stephen J Dollery, Ruth V Bushnell, F N U Yuqing, Rui Liu, Guoyu Lu, Gregory J Tobin, Ke Du

Journal: Lab Chip

PubMed ID: 36111877

Doi: 10.1039/d2lc00586g

Products & Services: PCR and Cloning

Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE

Authors: Brendan Miller, Su-Jeong Kim, Hemal H Mehta, Kevin Cao, Hiroshi Kumagai, Neehar Thumaty, Naphada Leelaprachakul, Henry Jiao, Joan Vaughan, Jolene Diedrich, Alan Saghatelian, Thalida E Arpawong, Eileen M Crimmins, Nilüfer Ertekin-Taner, Meral A Tubi, Evan T Hare, Meredith N Braskie, Léa Décarie-Spain, Scott E Kanoski, Francine Grodstein, David A Bennett, Lu Zhao, Arthur W Toga, Junxiang Wan, Kelvin Yen, Pinchas Cohen

Journal: Mol Psychiatry

PubMed ID: 36127429

Doi: 10.1038/s41380-022-01769-3

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Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover

Authors: Sihan Li, Ken Ikeuchi, Misaki Kato, Robert Buschauer, Takato Sugiyama, Shungo Adachi, Hideo Kusano, Tohru Natsume, Otto Berninghausen, Yoshitaka Matsuo, Thomas Becker, Roland Beckmann, Toshifumi Inada

Journal: Mol Cell

PubMed ID: 36113412

Doi: 10.1016/j.molcel.2022.08.018

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mRNA Vaccine Designing Using Chikungunya Virus E Glycoprotein through Immunoinformatics-Guided Approaches

Authors: Samavia Jaan, Aqal Zaman, Sarfraz Ahmed, Mohibullah Shah, Suvash Chandra Ojha

Journal: Vaccines (Basel)

PubMed ID: 36146554

Doi: 10.3390/vaccines10091476

Products & Services: Molecular Biology Tools

Peptide-Based HDL as an Effective Delivery System for Lipophilic Drugs to Restrain Atherosclerosis Development

Authors: Junwei Gao, Ziyun Li, Jing Li, Ping Song, Jinsheng Yang, Wei Xiao, Ning Li, Ruodan Xu

Journal: Int J Nanomedicine

PubMed ID: 36097444

Doi: 10.2147/IJN.S374736

Products & Services: Gene Synthesis

Small secreted peptides encoded on the wheat ( L) genome and their potential roles in stress responses

Authors: Dongdong Tian, Qi Xie, Zhichao Deng, Jin Xue, Wei Li, Zenglin Zhang, Yifei Dai, Bo Zheng, Tiegang Lu, Ive De Smet, Yongfeng Guo

Journal: Front Plant Sci

PubMed ID: 36212358

Doi: 10.3389/fpls.2022.1000297

Products & Services: Peptide Synthesis

Engineered CRISPR prime editors with compact, untethered reverse transcriptases

Authors: Julian Grünewald, Bret R Miller, Regan N Szalay, Peter K Cabeceiras, Christopher J Woodilla, Eliza Jane B Holtz, Karl Petri, J Keith Joung

Journal: Nat Biotechnol

PubMed ID: 36163548

Doi: 10.1038/s41587-022-01473-1

Products & Services: Plasmid DNA Preparation

Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes

Authors: Marcello Scala, Masashi Nishikawa, Hidenori Ito, Hidenori Tabata, Tayyaba Khan, Andrea Accogli, Laura Davids, Anna Ruiz, Pietro Chiurazzi, Gabriella Cericola, Björn Schulte, Kristin G Monaghan, Amber Begtrup, Annalaura Torella, Michele Pinelli, Anne Sophie Denommé-Pichon, Antonio Vitobello, Caroline Racine, Maria Margherita Mancardi, Courtney Kiss, Andrea Guerin, Wendy Wu, Elisabeth Gabau Vila, Bryan C Mak, Julian A Martinez-Agosto, Michael B Gorin, Bugrahan Duz, Yavuz Bayram, Claudia M B Carvalho, Jaime E Vengoechea, David Chitayat, Tiong Yang Tan, Bert Callewaert, Bernd Kruse, Lynne M Bird, Laurence Faivre, Marcella Zollino, Saskia Biskup, Pasquale Striano, Vincenzo Nigro, Mariasavina Severino, Valeria Capra, Gregory Costain, Koh Ichi Nagata

Journal: Brain

PubMed ID: 35851598

Doi: 10.1093/brain/awac106

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Fibrotic immune microenvironment remodeling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma

Authors: Xiaoyu Liu, Jingying Zhou, Haoran Wu, Shufen Chen, Lingyun Zhang, Wenshu Tang, Liang Duan, Ying Wang, Eleanor McCabe, Mengying Hu, Zhuo Yu, Hanzhuang Liu, Chung Hang Jonathan Choi, Joseph Jao-Yiu Sung, Leaf Huang, Rihe Liu, Alfred Sze-Lok Cheng

Journal: Mol Ther

PubMed ID: 36146933

Doi: 10.1016/j.ymthe.2022.09.012

Products & Services: Proteins, Expression, Isolation and Analysis

Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis

Authors: Govind Kunduri, Si-Hung Le, Valentina Baena, Nagampalli Vijaykrishna, Adam Harned, Kunio Nagashima, Daniel Blankenberg, Izumi Yoshihiro, Kedar Narayan, Takeshi Bamba, Usha Acharya, Jairaj K Acharya

Journal: PLoS Biol

PubMed ID: 36170207

Doi: 10.1371/journal.pbio.3001599

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Molecular fate-mapping of serum antibodies reveals the effects of antigenic imprinting on repeated immunization

Authors: Ariën Schiepers, Marije F L van 't Wout, Allison J Greaney, Trinity Zang, Hiromi Muramatsu, Paulo J C Lin, Ying K Tam, Luka Mesin, Tyler N Starr, Paul D Bieniasz, Norbert Pardi, Jesse D Bloom, Gabriel D Victora

Journal: biorxiv

PubMed ID: 36093344

Doi: 10.1101/2022.08.29.505743

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Frequency dependent growth of bacteria in living materials

Authors: Daniel D Lewis, Ting Gong, Yuanwei Xu, Cheemeng Tan

Journal: Front Bioeng Biotechnol

PubMed ID: 36159663

Doi: 10.3389/fbioe.2022.948483

Products & Services: Gene Synthesis

Exploring the Binding Affinity and Mechanism between ACE2 and the Trimers of Delta and Omicron Spike Proteins by Molecular Dynamics Simulation and Bioassay

Authors: Liping Zhou, Tingting Liu, Mengxia Mo, Yulong Shi, Leyun Wu, Yishui Li, Qiuping Qin, Weiliang Zhu, Chengkun Wu, Likun Gong, Zhijian Xu

Journal: J Chem Inf Model

PubMed ID: 36053674

Doi: 10.1021/acs.jcim.2c00881

Products & Services: Proteins, Expression, Isolation and Analysis

A Secreted Form of the Hepatitis E Virus ORF2 Protein: Design Strategy, Antigenicity and Immunogenicity

Authors: Zihao Chen, Shaoqi Guo, Guanghui Li, Dong Ying, Guiping Wen, Mujin Fang, Yingbin Wang, Zimin Tang, Zizheng Zheng, Ningshao Xia

Journal: Viruses

PubMed ID: 36298677

Doi: 10.3390/v14102122

Products & Services: ORF cDNA Clones/MolecularCloud

A LILRB1 variant with a decreased ability to phosphorylate SHP-1 leads to autoimmune diseases

Authors: Thivaratana Sinthuwiwat, Supranee Buranapraditkun, Wuttichart Kamolvisit, Siraprapa Tongkobpetch, Wanna Chetruengchai, Chalurmpon Srichomthong, Adjima Assawapitaksakul, Chureerat Phokaew, Patipark Kueanjinda, Tanapat Palaga, Tadech Boonpiyathad, Kanya Suphapeetiporn, Nattiya Hirankarn, Vorasuk Shotelersuk

Journal: Sci Rep

PubMed ID: 36104364

Doi: 10.1038/s41598-022-19334-x

Products & Services: Mutagenesis Services

Structural Basis of Substrate Promiscuity and Catalysis by the Reverse Prenyltransferase -Dimethylallyl-l-tryptophan Synthase from

Authors: Samuel A Eaton, Trey A Ronnebaum, Benjamin W Roose, David W Christianson

Journal: Biochemistry

PubMed ID: 36084241

Doi: 10.1021/acs.biochem.2c00350

Products & Services: Custom Vector Construction

FtlA and FtlB Are Candidates for Inclusion in a Next-Generation Multiantigen Subunit Vaccine for Lyme Disease

Authors: Andrew C Camire, Nathaniel S O'Bier, Dhara T Patel, Nicholas A Cramer, Reinhard K Straubinger, Edward B Breitschwerdt, Rebecca A Funk, Richard T Marconi

Journal: Infect Immun

PubMed ID: 36102656

Doi: 10.1128/iai.00364-22

Products & Services: Codon Optimization

Targeting extracellular matrix remodeling sensitizes glioblastoma to ionizing radiation

Authors: Varsha Thakur, Vijay S Thakur, Brittany Aguila, Tatiana I Slepak, Man Wang, Wei Song, Mohini Konai, Shahriar Mobashery, Mayland Chang, Ayush B Rana, Dazhi Wang, Juliano Tiburcio de Freitas, Sakir Humayun Gultekin, Scott M Welford, Michael E Ivan, Barbara Bedogni

Journal: Neurooncol Adv

PubMed ID: 36212741

Doi: 10.1093/noajnl/vdac147

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A miniaturized bionic ocean-battery mimicking the structure of marine microbial ecosystems

Authors: Huawei Zhu, Liru Xu, Guodong Luan, Tao Zhan, Zepeng Kang, Chunli Li, Xuefeng Lu, Xueli Zhang, Zhiguang Zhu, Yanping Zhang, Yin Li

Journal: Nat Commun

PubMed ID: 36153325

Doi: 10.1038/s41467-022-33358-x

Products & Services: Codon Optimization

Proton-transporting heliorhodopsins from marine giant viruses

Authors: Shoko Hososhima, Ritsu Mizutori, Rei Abe-Yoshizumi, Andrey Rozenberg, Shunta Shigemura, Alina Pushkarev, Masae Konno, Kota Katayama, Keiichi Inoue, Satoshi P Tsunoda, Oded Béjà, Hideki Kandori

Journal: Elife

PubMed ID: 36065640

Doi: 10.7554/eLife.78416

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Engineering sorghum for higher 4-hydroxybenzoic acid content

Authors: Chien-Yuan Lin, Yang Tian, Kimberly Nelson-Vasilchik, Joel Hague, Ramu Kakumanu, Mi Yeon Lee, Venkataramana R Pidatala, Jessica Trinh, Christopher M De Ben, Jutta Dalton, Trent R Northen, Edward E K Baidoo, Blake A Simmons, John M Gladden, Corinne D Scown, Daniel H Putnam, Albert P Kausch, Henrik V Scheller, Aymerick Eudes

Journal: Metab Eng Commun

PubMed ID: 36188638

Doi: 10.1016/j.mec.2022.e00207

Products & Services: Codon Optimization

A soybean sodium/hydrogen exchanger GmNHX6 confers plant alkaline salt tolerance by regulating Na/K homeostasis

Authors: Ting Jin, Jiaxin An, Huadong Xu, Jie Chen, Lang Pan, Ranran Zhao, Ning Wang, Junyi Gai, Yan Li

Journal: Front Plant Sci

PubMed ID: 36204047

Doi: 10.3389/fpls.2022.938635

Products & Services: DNA Sequencing

Expressing the Pro-Apoptotic Reaper Protein via Insertion into the Structural Open Reading Frame of Sindbis Virus Reduces the Ability to Infect Mosquitoes

Authors: Alexis Carpenter, Scott R Santos, Rollie J Clem

Journal: Viruses

PubMed ID: 36146841

Doi: 10.3390/v14092035

Products & Services: Proteins, Expression, Isolation and Analysis

Characteristics of NtCCD1-3 from tobacco, and protein engineering of the CCD1 to enhance -ionone production in yeast

Authors: Xiaowei Gong, Fan Li, Yupeng Liang, Xiulin Han, Mengliang Wen

Journal: Front Microbiol

PubMed ID: 36212872

Doi: 10.3389/fmicb.2022.1011297

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Transport of acylated anthocyanins by the Arabidopsis ATP-binding cassette transporters AtABCC1, AtABCC2, and AtABCC14

Authors: John V Dean, Morgan Willis, Laith Shaban

Journal: Physiol Plant

PubMed ID: 36121340

Doi: 10.1111/ppl.13780

Products & Services: Peptide Synthesis

Streptococcus mutans glutamate binding protein (GlnH) as antigen target for a mucosal anti-caries vaccine

Authors: Gisela de Souza Pereira, Milene Tavares Batista, Nayara Fernanda Barros Dos Santos, Hélic Moreira Passos, Dalva Adelina da Silva, Ewerton Lucena Ferreira, Luís Carlos de Souza Ferreira, Rita de Cássia Café Ferreira

Journal: Braz J Microbiol

PubMed ID: 36098933

Doi: 10.1007/s42770-022-00823-0

Products & Services: GenParts™ DNA Fragments

Farnesyl pyrophosphate compartmentalization in the green microalga Chlamydomonas reinhardtii during heterologous (E)-α-bisabolene production

Authors: Julian Wichmann, Annibel Eggert, Liam D H Elbourne, Ian T Paulsen, Kyle J Lauersen, Olaf Kruse

Journal: Microb Cell Fact

PubMed ID: 36104783

Doi: 10.1186/s12934-022-01910-5

Products & Services: Gene Synthesis

The positive regulatory loop of TCF4N/p65 promotes glioblastoma tumourigenesis and chemosensitivity

Authors: Yaling Hu, Bo Zhang, Peihua Lu, Jingying Wang, Cheng Chen, Ying Yin, Quan Wan, Jingjing Wang, Jiantong Jiao, Xiangming Fang, Zhening Pu, Lingli Gong, Li Ji, Lingpeng Zhu, Rui Zhang, Jia Zhang, Xusheng Yang, Qing Wang, Zhaohui Huang, Jian Zou

Journal: Clin Transl Med

PubMed ID: 36116131

Doi: 10.1002/ctm2.1042

Products & Services: Proteins, Expression, Isolation and Analysis

Downregulation of Elovl5 promotes breast cancer metastasis through a lipid-droplet accumulation-mediated induction of TGF-β receptors

Authors: Trinh-Le-Vi Kieu, Léa Pierre, Valentin Derangère, Sabrina Perrey, Caroline Truntzer, Antoine Jalil, Sébastien Causse, Emma Groetz, Adélie Dumont, Laura Guyard, Laurent Arnould, Jean-Paul Pais de Barros, Lionel Apetoh, Cédric Rébé, Emeric Limagne, Tony Jourdan, Laurent Demizieux, David Masson, Charles Thomas, François Ghiringhelli, Mickaël Rialland

Journal: Cell Death Dis

PubMed ID: 36056008

Doi: 10.1038/s41419-022-05209-6

Products & Services: Gene Synthesis

A sample-to-answer, quantitative real-time PCR system with low-cost, gravity-driven microfluidic cartridge for rapid detection of SARS-CoV-2, influenza A/B, and human papillomavirus 16/18

Authors: Yunfeng Zai, Chao Min, Zunliang Wang, Yongjun Ding, Huan Zhao, Enben Su, Nongyue He

Journal: Lab Chip

PubMed ID: 35972195

Doi: 10.1039/d2lc00434h

Products & Services: Gene Synthesis

An Unexpected Encounter: Respiratory Syncytial Virus Nonstructural Protein 1 Interacts with Mediator Subunit MED25

Authors: Tessa Van Royen, Koen Sedeyn, George D Moschonas, Wendy Toussaint, Marnik Vuylsteke, Delphi Van Haver, Francis Impens, Sven Eyckerman, Irma Lemmens, Jan Tavernier, Bert Schepens, Xavier Saelens

Journal: J Virol

PubMed ID: 36102648

Doi: 10.1128/jvi.01297-22

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Identification of a Potential Inhibitor (MCULE-8777613195-0-12) of New Delhi Metallo-β-Lactamase-1 (NDM-1) Using In Silico and In Vitro Approaches

Authors: Ghazala Muteeb, Md Tabish Rehman, Mohamed F AlAjmi, Mohammad Aatif, Mohd Farhan, Sheeba Shafi

Journal: Molecules

PubMed ID: 36144666

Doi: 10.3390/molecules27185930

Products & Services: Proteins, Expression, Isolation and Analysis

Kinetic Model and Numerical Simulation of Microbial Growth, Migration, and Oil Displacement in Reservoir Porous Media

Authors: Chuanjin Yao, Xiangxiang Meng, Xiaohuan Qu, Tianxiang Cheng, Qi'an Da, Kai Zhang, Guanglun Lei

Journal: ACS Omega

PubMed ID: 36120076

Doi: 10.1021/acsomega.2c04120

Products & Services: Gene Synthesis

Genome-wide in vivo screen of circulating tumor cells identifies as a regulator of metastasis

Authors: Fan Xia, Yuan Ma, Kangfu Chen, Bill Duong, Sharif Ahmed, Randy Atwal, David Philpott, Troy Ketela, Jennifer Pantea, Sichun Lin, Stephane Angers, Shana O Kelley

Journal: Sci Adv

PubMed ID: 36054348

Doi: 10.1126/sciadv.abo7792

Products & Services: Plasmid DNA Preparation

Antimicrobial Peptide Mechanism Studied by Scattering-Guided Molecular Dynamics Simulation

Authors: Robert Allsopp, Anna Pavlova, Tyler Cline, Aria M Salyapongse, Richard E Gillilan, Y Peter Di, Berthony Deslouches, Jeffery B Klauda, James C Gumbart, Stephanie Tristram-Nagle

Journal: J Phys Chem B

PubMed ID: 36067064

Doi: 10.1021/acs.jpcb.2c03193

Products & Services: Peptide Synthesis

Modification of the HLA-A*24:02 Peptide Binding Pocket Enhances Cognate Peptide-Binding Capacity and Antigen-Specific T Cell Activation

Authors: Kenji Murata, Dalam Ly, Hiroshi Saijo, Yukiko Matsunaga, Kenji Sugata, Fumie Ihara, Daisuke Oryoji, Yota Ohashi, Kayoko Saso, Chung-Hsi Wang, Evey Y F Zheng, Brian D Burt, Marcus O Butler, Naoto Hirano

Journal: J Immunol

PubMed ID: 36165170

Doi: 10.4049/jimmunol.2200305

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Comparison of SARS-CoV-2 spike antibody quantitative titer reporting using the World Health Organization International Standard Units by four commercial assays

Authors: Ran Zhuo, Carmen Charlton, Sabrina Plitt, L Alexa Thompson, Sheila Braun, Jacqueline Day, Carla Osiowy, Graham Tipples, Jamil N Kanji

Journal: J Clin Virol

PubMed ID: 36108404

Doi: 10.1016/j.jcv.2022.105292

Truncated Tau caused by intron retention is enriched in Alzheimer's disease cortex and exhibits altered biochemical properties

Authors: Zhen-Kai Ngian, Yow-Yong Tan, Ching-Thong Choo, Wei-Qi Lin, Chao-Yong Leow, Shan-Jie Mah, Mitchell Kim-Peng Lai, Christopher Li-Hsian Chen, Chin-Tong Ong

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36067305

Doi: 10.1073/pnas.2204179119

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Reverse Transcription-Loop-Mediated Isothermal Amplification-CRISPR-Cas13a Technology as a Promising Diagnostic Tool for SARS-CoV-2

Authors: Concha Ortiz-Cartagena, Laura Fernández-García, Lucia Blasco, Olga Pacios, Inés Bleriot, María López, Rafael Cantón, María Tomás

Journal: Microbiol Spectr

PubMed ID: 36169448

Doi: 10.1128/spectrum.02398-22

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Host adaptation of codon usage in SARS-CoV-2 from mammals indicates potential natural selection and viral fitness

Authors: Yanan Fu, Yanping Huang, Jingjing Rao, Feng Zeng, Ruiping Yang, Huabing Tan, Zhixin Liu, Weixing Du, Long Liu

Journal: Arch Virol

PubMed ID: 36166106

Doi: 10.1007/s00705-022-05612-6

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Context-based sensing of orthosomycin antibiotics by the translating ribosome

Authors: Kyle Mangano, James Marks, Dorota Klepacki, Chayan Kumar Saha, Gemma C Atkinson, Nora Vázquez-Laslop, Alexander S Mankin

Journal: Nat Chem Biol

PubMed ID: 36138139

Doi: 10.1038/s41589-022-01138-9

Products & Services: Proteins, Expression, Isolation and Analysis

Secondary IDH1 resistance mutations and oncogenic IDH2 mutations cause acquired resistance to ivosidenib in cholangiocarcinoma

Authors: James M Cleary, Betty Rouaisnel, Antoine Daina, Srivatsan Raghavan, Lauren A Roller, Brandon M Huffman, Harshabad Singh, Patrick Y Wen, Nabeel Bardeesy, Vincent Zoete, Brian M Wolpin, Julie-Aurore Losman

Journal: NPJ Precis Oncol

PubMed ID: 36056177

Doi: 10.1038/s41698-022-00304-5

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Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity

Authors: Arne Søraas, Gunnveig Grødeland, Beathe Kiland Granerud, Thor Ueland, Andreas Lind, Børre Fevang, Sarah L Murphy, Camilla Huse, Anders Benteson Nygaard, Anne Katrine Steffensen, Huda Al-Baldawi, Mona Holberg-Petersen, Lise Lima Andresen, Camilla Ågnes, Trine Ranheim, Ylva Schanke, Mette Istre, John Arne Dahl, Adity Chopra, Susanne Dudman, Mari Kaarbø, Jan Terje Andersen, Eline Benno Vaage, Trung The Tran, John Torgils Vaage, Annika E Michelsen, Fredrik Müller, Pål Aukrust, Bente Halvorsen, Tuva B Dahl, Jan Cato Holter, Fridtjof Lund-Johansen

Journal: Front Immunol

PubMed ID: 36159859

Doi: 10.3389/fimmu.2022.964525

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