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A novel site on dual-specificity phosphatase MKP7/DUSP16 is required for catalysis and MAPK binding
Authors: Shanelle Shillingford, Lei Zhang, Yulia Surovtseva, Sam Dorry, Elias Lolis, Anton M Bennett
Journal: J Biol Chem
PubMed ID: 36272649
Doi: 10.1016/j.jbc.2022.102617
Products & Services: Mutagenesis Services   
Rat Group IIA Secreted Phospholipase A Binds to Cytochrome c Oxidase and Inhibits Its Activity: A Possible Episode in the Development of Alzheimer's Disease
Authors: Adrijan Ivanušec, Jernej Šribar, Adrijana Leonardi, Maja Zorović, Marko Živin, Igor Križaj
Journal: Int J Mol Sci
PubMed ID: 36293221
Doi: 10.3390/ijms232012368
Products & Services: Plasmid DNA Preparation   
SCF regulates G2-M progression through control of CCNL1 ubiquitination
Authors: Siobhan O'Brien, Susan Kelso, Zachary Steinhart, Stephen Orlicky, Monika Mis, Yunhye Kim, Sichun Lin, Frank Sicheri, Stephane Angers
Journal: EMBO Rep
PubMed ID: 36278408
Doi: 10.15252/embr.202255044
Products & Services: Catalog Peptides   
CD4 T cell epitope abundance in ferritin core potentiates responses to hemagglutinin nanoparticle vaccines
Authors: Sean A Nelson, Katherine A Richards, Maryah A Glover, Francisco A Chaves, Michelle C Crank, Barney S Graham, Masaru Kanekiyo, Andrea J Sant
Journal: npj Vaccines
PubMed ID: 36289232
Doi: 10.1038/s41541-022-00547-0
Products & Services: Peptide Synthesis   
Sorting nexin-dependent therapeutic targeting of oncogenic epidermal growth factor receptor
Authors: Benjamin Atwell, Cheng-Yu Chen, Matthew Christofferson, William R Montfort, Joyce Schroeder
Journal: Cancer Gene Ther
PubMed ID: 36253541
Doi: 10.1038/s41417-022-00541-7
Products & Services: Peptide Synthesis   
Structure of the core human NADPH oxidase NOX2
Authors: Sigrid Noreng, Naruhisa Ota, Yonglian Sun, Hoangdung Ho, Matthew Johnson, Christopher P Arthur, Kellen Schneider, Isabelle Lehoux, Christopher W Davies, Kyle Mortara, Kit Wong, Dhaya Seshasayee, Matthieu Masureel, Jian Payandeh, Tangsheng Yi, James T Koerber
Journal: Nat Commun
PubMed ID: 36241643
Doi: 10.1038/s41467-022-33711-0
Products & Services: Gene Synthesis   
Target RNA activates the protease activity of Craspase to confer antiviral defense
Authors: Xi Liu, Laixing Zhang, Hao Wang, Yu Xiu, Ling Huang, Zhengyu Gao, Ningning Li, Feixue Li, Weijia Xiong, Teng Gao, Yi Zhang, Maojun Yang, Yue Feng
Journal: Mol Cell
PubMed ID: 36306795
Doi: 10.1016/j.molcel.2022.10.007
Products & Services: Gene Synthesis   
Deciphering the virulence potential of Listeria monocytogenes in the Norwegian meat and salmon processing industry by combining whole genome sequencing and in vitro data
Authors: Eva Wagner, Annette Fagerlund, Sarah Thalguter, Merete Rusås Jensen, Even Heir, Trond Møretrø, Birgitte Moen, Solveig Langsrud, Kathrin Rychli
Journal: Int J Food Microbiol
PubMed ID: 36240603
Doi: 10.1016/j.ijfoodmicro.2022.109962
TMT-Based Quantitative Proteomic Analysis Reveals Downregulation of ITGAL and Syk by the Effects of Cycloastragenol in OVA-Induced Asthmatic Mice
Authors: Xueyi Zhu, Baojun Liu, Zhenhui Ruan, Mengmeng Chen, Congcong Li, Hanlin Shi, Xi Huang, Hang Yu, Yaolong Zhou, Hehua Zhu, Jing Sun, Ying Wei, Weifang Xu, Jingcheng Dong
Journal: Oxid Med Cell Longev
PubMed ID: 36329800
Doi: 10.1155/2022/6842530
Molecular Effects of Iodine-Biofortified Lettuce in Human Gastrointestinal Cancer Cells
Authors: Olga Sularz, Aneta Koronowicz, Cayla Boycott, Sylwester Smoleń, Barbara Stefanska
Journal: Nutrients
PubMed ID: 36296971
Doi: 10.3390/nu14204287
Photoprotective Effects of Cannabidiol against Ultraviolet-B-Induced DNA Damage and Autophagy in Human Keratinocyte Cells and Mouse Skin Tissue
Authors: Yanmei Li, Dan Hao, Danfeng Wei, Yue Xiao, Lian Liu, Xiaoxue Li, Lian Wang, Yu Gan, Wei Yan, Bowen Ke, Xian Jiang
Journal: Molecules
PubMed ID: 36235276
Doi: 10.3390/molecules27196740
Molecular characterization of peptidoglycan recognition proteins from Mytilus coruscus
Authors: Zhi Liao, Zongxin Yang, Ying Wang, Jianyu He, Zhijiang He, Xiaolin Zhang, Isabella Buttino, Pengzhi Qi, Meihua Fan, Baoying Guo, Xiaojun Yan, Menglan He
Journal: Fish Shellfish Immunol
PubMed ID: 36272520
Doi: 10.1016/j.fsi.2022.10.018
Regulation of Prolactin Release at the End Stage of Chicken Embryogenesis
Authors: Norio Kansaku, Shin Wakui, Tomohiro Sasanami, Takeshi Ohkubo
Journal: J Poult Sci
PubMed ID: 36382060
Doi: 10.2141/jpsa.0220023
TBC1D18 is a Rab5-GAP that coordinates endosome maturation together with Mon1
Authors: Shu Hiragi, Takahide Matsui, Yuriko Sakamaki, Mitsunori Fukuda
Journal: J Cell Biol
PubMed ID: 36197338
Doi: 10.1083/jcb.202201114
The diurnal emission of floral scent in Oncidium hybrid orchid is controlled by CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) through the direct regulation on terpene synthase
Authors: Chao-Wei Yeh, Hui-Qin Zhong, Yung-Feng Ho, Zhi-Hong Tian, Kai-Wun Yeh
Journal: BMC Plant Biol
PubMed ID: 36195835
Doi: 10.1186/s12870-022-03850-z
Highly efficient hybridoma generation and screening strategy for anti-PD-1 monoclonal antibody development
Authors: Tanapati Phakham, Chatikorn Boonkrai, Tossapon Wongtangprasert, Thittaya Audomsun, Chadaporn Attakitbancha, Pijitra Saelao, Phijitra Muanwien, Sarintip Sooksai, Nattiya Hirankarn, Trairak Pisitkun
Journal: Sci Rep
PubMed ID: 36273231
Doi: 10.1038/s41598-022-20560-6
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Hydrogen-bonds mediate liquid-liquid phase separation of mussel derived adhesive peptides
Authors: Qi Guo, Guijin Zou, Xuliang Qian, Shujun Chen, Huajian Gao, Jing Yu
Journal: Nat Commun
PubMed ID: 36182948
Doi: 10.1038/s41467-022-33545-w
Products & Services: Catalog Peptides   
Ultra-sensitive molecular detection of gene fusions from RNA using ASPYRE
Authors: Eleanor R Gray, Justyna M Mordaka, Efthimia R Christoforou, Kristine von Bargen, Nicola D Potts, Christina Xyrafaki, Ana-Luisa Silva, Magdalena Stolarek-Januszkiewicz, Katarzyna Anton, Paulina K Powalowska, Simonetta Andreazza, Alessandro Tomassini, Rebecca N Palmer, Aishling Cooke, Robert J Osborne, Barnaby W Balmforth
Journal: BMC Med Genomics
PubMed ID: 36224552
Doi: 10.1186/s12920-022-01363-0
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An experimental test of the nicotinic hypothesis of COVID-19
Authors: Nicole E Godellas, Gisela D Cymes, Claudio Grosman
Journal: Proc Natl Acad Sci U S A
PubMed ID: 36279466
Doi: 10.1073/pnas.2204242119
Products & Services: Catalog Peptides   
Long noncoding RNA-mediated activation of PROTOR1/PRR5-AKT signaling shunt downstream of PI3K in triple-negative breast cancer
Authors: Zhenbo Tu, Yi Hu, Devesh Raizada, Mahmoud A Bassal, Daniel G Tenen, Antoine E Karnoub
Journal: Proc Natl Acad Sci U S A
PubMed ID: 36269860
Doi: 10.1073/pnas.2203180119
Products & Services: Mammalian Expression   
Presence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibodies Among Vietnamese Healthcare Workers by Dosing Interval for ChAdOx1 nCoV-19 Vaccine
Authors: Dien M Vu, Diep T B Vu, Thuy T T Do, Allison E Olmsted, Bach H Dao, Truc T Thai, Chi L Nguyen, Nhung T T Le, Tuan A Le, Hien T T Bui, Thach N Pham, Matthew R Moore
Journal: Clin Infect Dis
PubMed ID: 35723271
Doi: 10.1093/cid/ciac493
Products & Services: Recombinant Proteins   
AlphaFold version 20 elucidates the binding mechanism between VIPR2 and KS-133, and reveals an S-S bond (Cys-Cys) formation of functional significance for VIPR2
Authors: Kotaro Sakamoto, Satoshi Asano, Yukio Ago, Takatsugu Hirokawa
Journal: Biochem Biophys Res Commun
PubMed ID: 36332470
Doi: 10.1016/j.bbrc.2022.10.071
Products & Services: Plasmid DNA Preparation   
Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease
Authors: Hangchen Hu, Qian Wang, Haixia Su, Qiang Shao, Wenfeng Zhao, Guofeng Chen, Minjun Li, Yechun Xu
Journal: Angew Chem Int Ed Engl
PubMed ID: 36308706
Doi: 10.1002/anie.202212378
Products & Services: Codon Optimization   
Recombinant acetylxylan esterase of Halalkalibacterium halodurans NAH-Egypt: molecular and biochemical study.
Authors: Amira M Embaby , Hoda E Mahmoud
Journal: AMB Express .
PubMed ID: 36289146
Doi: A10.1186/s13568-022-01476-w.
Systemic and Mucosal Humoral Immune Response Induced by Three Doses of the BNT162b2 SARS-CoV-2 mRNA Vaccines
Authors: Roberta Mancuso, Simone Agostini, Lorenzo Agostino Citterio, Debora Chiarini, Maria Antonia Santangelo, Mario Clerici
Journal: Vaccines (Basel)
PubMed ID: 36298514
Doi: 10.3390/vaccines10101649
Products & Services: Serology SARS-Cov-2 detection kits   
PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PDL1 bias-dependent way
Authors: Xiaolu Yu, Yiru Long , Binfan Chen , Yongliang Tong , Mengwen Shan , Xiaomin Jia , Chao Hu , Meng Liu , Ji Zhou , Feng Tang , Henglei Lu , Runqiu Chen , Pan Xu , Wei Huang , Jin Ren , Yakun Wan , Jianhua Sun , Jia Li , Guangyi Jin , Likun Gong
Journal: J Immunother Cancer .
PubMed ID: 36253000
Doi: 10.1136/jitc-2022-004590
Products & Services: Recombinant Proteins   
PCDetection: PolyA-CRISPR/Cas12a-based miRNA detection without PAM restriction
Authors: Mingtian Zhong , Kaizhao Chen , Wenjun Sun , Xiangyang Li , Shisheng Huang , Qingzhou Meng , Bo Sun , Xingxu Huang , Xinjie Wang , Xiaodong Ma , Peixiang Ma
Journal: Biosens Bioelectron
PubMed ID: 35797934
Doi: 10.1016/j.bios.2022.114497
Products & Services: Gene Synthesis   
Duration of antiretroviral therapy impacts the degree of residual SIV infection in the gut in long-term non-progressing Chinese rhesus macaques
Authors: Antonio Solis-Leal, Ann-Marie May, Mahesh Mohan, Jason P Dufour, Binhua Ling
Journal: J Med Virol
PubMed ID: 36181356
Doi: 10.1002/jmv.28185
Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy
Authors: Wentao Fan, Chenchen Ding, Shuhui Liu, Xiaona Gao, Xiaofei Shen, Marthe De Boevre, Zhangshan Gao, Mengcong Li, Shuo Zhang, Yufan Miao, Wenxian Guan, Guangliang Liu, Liping Yan, Sarah De Saeger, Suquan Song
Journal: Cell Rep
PubMed ID: 36223738
Doi: 10.1016/j.celrep.2022.111454
Fructose-6-phosphate-2-kinase/fructose-2,6-bisphosphatase regulates energy metabolism and synthesis of storage products in developing rice endosperm
Authors: Xiaoli Chen , Yi Ji , Weiying Zhao , Huanying Niu , Xue Yang , Xiaokang Jiang , Yipeng Zhang , Jie Lei , Hang Yang , Rongbo Chen , Chuanwei Gu , Hongyi Xu , Hui Dong , Erchao Duan , Xuan Teng , Yunlong Wang , Yuanyan Zhang , Wenwei Zhang , Yihua Wang , Jianmin Wan
Journal: Plant Sci
PubMed ID: 36270512
Doi: 10.1016/j.plantsci.2022.111503
The Detection of Immunity against WT1 and SMAD4 of EpCAM Cancer Cells in Malignant Pleural Effusion
Authors: Terutsugu Koya, Yo Niida, Misa Togi, Kenichi Yoshida, Takuya Sakamoto, Hiroki Ura, Sumihito Togi, Tomohisa Kato, Sohsuke Yamada, Haruo Sugiyama, Shigeo Koido, Shigetaka Shimodaira
Journal: Int J Mol Sci
PubMed ID: 36293034
Doi: 10.3390/ijms232012177
Products & Services: Peptide Synthesis   
Isobutanol production by combined and metabolic engineering
Authors: Mamta Gupta, Matthew Wong, Kamran Jawed, Kamil Gedeon, Hannah Barrett, Marcelo Bassalo, Clifford Morrison, Danish Eqbal, Syed Shams Yazdani, Ryan T Gill, Jiaqi Huang, Marc Douaisi, Jonathan Dordick, Georges Belfort, Mattheos A G Koffas
Journal: Metab Eng Commun
PubMed ID: 36325486
Doi: 10.1016/j.mec.2022.e00210
Products & Services: Plasmid DNA Preparation   
Multifunctional chemical inhibitors of the florigen activation complex discovered by structure-based high-throughput screening
Authors: Ken-Ichiro Taoka, Ikumi Kawahara, Shoko Shinya, Ken-Ichi Harada, Eiki Yamashita, Zenpei Shimatani, Kyoko Furuita, Tomoaki Muranaka, Tokitaka Oyama, Rie Terada, Atsushi Nakagawa, Toshimichi Fujiwara, Hiroyuki Tsuji, Chojiro Kojima
Journal: Plant J
PubMed ID: 36288411
Doi: 10.1111/tpj.16008
Products & Services: Peptide Synthesis   
The large plasmid carried class 1 integrons mediated multidrug resistance of foodborne Indiana
Authors: Xuefeng Wang, Tian Wang, Mengjiao Guo, Chengcheng Zhang, Zongyi Bo, Yantao Wu, Guoxiang Chao
Journal: Front Microbiol
PubMed ID: 36312970
Doi: 10.3389/fmicb.2022.991326
Products & Services: Custom DNA/RNA Oligos   
Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp)
Authors: Wen Meng, Siying Guo, Simon Cao, Masahiro Shuda, Lindsey R Robinson-McCarthy, Kevin R McCarthy, Yoko Shuda, Alberto E Paniz Mondolfi, Clare Bryce, Zachary Grimes, Emilia M Sordillo, Carlos Cordon-Cardo, Pengfei Li, Hu Zhang, Stanley Perlman, Haitao Guo, Shou-Jiang Gao, Yuan Chang, Patrick S Moore
Journal: J Med Virol
PubMed ID: 36271490
Doi: 10.1002/jmv.28246
Products & Services: Peptide Synthesis   
A simple thermodynamic description of phase separation of Nup98 FG domains
Authors: Sheung Chun Ng, Dirk Görlich
Journal: Nat Commun
PubMed ID: 36257947
Doi: 10.1038/s41467-022-33697-9
Products & Services: Bacterial Expression   
A novel rhesus macaque model of Huntington's disease recapitulates key neuropathological changes along with motor and cognitive decline
Authors: Alison R Weiss, William A Liguore, Kristin Brandon, Xiaojie Wang, Zheng Liu, Jacqueline S Domire, Dana Button, Sathya Srinivasan, Christopher D Kroenke, Jodi L McBride
Journal: Elife
PubMed ID: 36205397
Doi: 10.7554/eLife.77568
Products & Services: Plasmid DNA Preparation   
Comparative proteomic analysis reveals novel insights into the continuous cropping induced response in Scrophularia ningpoensis
Authors: Jiachen Sun, Xuejiao Li, Zhuo Qu, Huairui Wang, Yao Cheng, Shengjie Dong, Hui Zhao
Journal: J Sci Food Agric
PubMed ID: 36271763
Doi: 10.1002/jsfa.12284
A dataset comprised of binding interactions for 104,972 antibodies against a SARS-CoV-2 peptide
Authors: Emily Engelhart, Ryan Emerson, Leslie Shing, Chelsea Lennartz, Daniel Guion, Mary Kelley, Charles Lin, Randolph Lopez, David Younger, Matthew E Walsh
Journal: Sci Data
PubMed ID: 36289234
Doi: 10.1038/s41597-022-01779-4
Products & Services: GenParts™ DNA Fragments   
ICG-Dimeric Her2-Specific Affibody Conjugates for Tumor Imaging and Photothermal Therapy for Her2-Positive Tumors
Authors: Dianlong Jia, Huimin Liu, Shuhui Zheng, Dandan Yuan, Ruohan Sun, Fei Wang, Yang Li, Hui Li, Fengjiao Yuan, Qing Fan, Zhenxiong Zhao
Journal: Mol Pharm
PubMed ID: 36315025
Doi: 10.1021/acs.molpharmaceut.2c00708
Products & Services: Bacterial Expression   
Cancer stem cell antigen nanodisc cocktail elicits anti-tumor immune responses in melanoma
Authors: Marisa E Aikins, You Qin, Hannah E Dobson, Alireza Hassani Najafabadi, Kexing Lyu, Yao Xu, Ying Xin, Anna Schwendeman, Max S Wicha, Alfred E Chang, Qiao Li, James J Moon
Journal: J Control Release
PubMed ID: 36206945
Doi: 10.1016/j.jconrel.2022.09.061
Products & Services: Peptide Synthesis   
Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library
Authors: Devan J Shell, Justin M Rectenwald, Peter H Buttery, Rebecca L Johnson, Caroline A Foley, Shiva K R Guduru, Mélanie Uguen, Juanita Sanchez Rubiano, Xindi Zhang, Fengling Li, Jacqueline L Norris-Drouin, Matthew Axtman, P Brian Hardy, Masoud Vedadi, Stephen V Frye, Lindsey I James, Kenneth H Pearce
Journal: SLAS Discov
PubMed ID: 36272689
Doi: 10.1016/j.slasd.2022.10.003
Products & Services: Recombinant Proteins   
Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus
Authors: Iktae Kim, Alyssa Dubrow, Bryan Zuniga, Baoyu Zhao, Noah Sherer, Abhishek Bastiray, Pingwei Li, Jae-Hyun Cho
Journal: Nat Commun
PubMed ID: 36182933
Doi: 10.1038/s41467-022-33554-9
A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers
Authors: Rongjie Cheng, Fanying Li, Maolei Zhang, Xin Xia, Jianzhuang Wu, Xinya Gao, Huangkai Zhou, Zhi Zhang, Nunu Huang, Xuesong Yang, Yaliang Zhang, Shunli Shen, Tiebang Kang, Zexian Liu, Feizhe Xiao, Hongwei Yao, Jianbo Xu, Chao Yan, Nu Zhang
Journal: Cell Res
PubMed ID: 36241718
Doi: 10.1038/s41422-022-00726-7
Products & Services: Plasmid DNA Preparation   
On the role of cell surface associated, mucin-like glycoproteins in the pennate diatom Craspedostauros australis (Bacillariophyceae)
Authors: Nicole Poulsen, Helene Hennig, Veikko F Geyer, Stefan Diez, Richard Wetherbee, Sorel Fitz-Gibbon, Matteo Pellegrini, Nils Kröger
Journal: J Phycol
PubMed ID: 36199194
Doi: 10.1111/jpy.13287
Products & Services: Polyclonal Antibody Services   
Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage
Authors: Qianying Lv, Xinli Han, Jiajia Ni, Qianqian Ma, Rufeng Dai, Jiaojiao Liu, Jialu Liu, Yihui Zhai, Qian Shen, Li Sun, Haimei Liu, Jia Rao, Hong Xu
Journal: Cell Death Dis
PubMed ID: 36229446
Doi: 10.1038/s41419-022-05313-7
Products & Services: Gene Synthesis   
Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma
Authors: Tilman L B Hölting, Florencia Cidre-Aranaz, Dana Matzek, Bastian Popper, Severin J Jacobi, Cornelius M Funk, Florian H Geyer, Jing Li, Ignazio Piseddu, Bruno L Cadilha, Stephan Ledderose, Jennifer Zwilling, Shunya Ohmura, David Anz, Annette Künkele, Frederick Klauschen, Thomas G P Grünewald, Maximilian M L Knott
Journal: Mol Cancer
PubMed ID: 36229873
Doi: 10.1186/s12943-022-01641-6
Products & Services: Recombinant Proteins   
Active Pharmaceutical Ingredient Uptake by Zebrafish (Danio rerio) Oct2 (slc22a2) Transporter Expressed in Xenopus laevis Oocytes
Authors: Elisabeth D Chang, Stewart F Owen, Christer Hogstrand, Nic R Bury
Journal: Environ Toxicol Chem
PubMed ID: 36102855
Doi: 10.1002/etc.5480
Products & Services: Gene Synthesis   
Combating the SARS-CoV-2 Omicron (BA1) and BA2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Authors: Yingdan Wang, Xiang Zhang, Yunping Ma, Yanqun Wang, Wuqiang Zhan, Qinwen Zheng, Meng Zhang, Ping Ji, Mei Liu, Qianying Liu, Tingting Sun, Tongyu Zhu, Yumei Wen, Lei Sun, Jincun Zhao, Fan Wu, Zhenguo Chen, Jinghe Huang
Journal: Cell Discov
PubMed ID: 36207299
Doi: 10.1038/s41421-022-00463-6
Products & Services: Codon Optimization   
Discovery and functional characterization of the oncogenicity and targetability of a novel gene fusion in pediatric angiosarcoma
Authors: Payal Jain, Sudarshan Iyer, Joshua Straka, Lea F Surrey, Jennifer Pogoriler, Harry Han, Tiffany Smith, Christine Busch, Elizabeth Fox, Marilyn Li, Angela J Waanders, Adam Resnick, Monika A Davare
Journal: Cold Spring Harb Mol Case Stud
PubMed ID: 36307212
Doi: 10.1101/mcs.a006222
Products & Services: Plasmid DNA Preparation   

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