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Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions

Authors: Da Zou, Zeming Wu, Xin Yi, Yue Hui, Guangze Yang, Yun Liu, Haofei Wang, Anastasia Brooks, Haolu Wang, Xin Liu, Zhi Ping Xu, Michael S Roberts, Huajian Gao, Chun-Xia Zhao

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36574680

Doi: 10.1073/pnas.2214757120

Products & Services: Peptide Synthesis

A novel method for silkworm cocoons self-degumming and its effect on silk fibers

Authors: Riyuan Wang, Yuancheng Wang, Jianxin Song, Chi Tian, Xinyuan Jing, Ping Zhao, Qingyou Xia

Journal: J Adv Res

PubMed ID: 36572337

Doi: 10.1016/j.jare.2022.12.005

Products & Services: Molecular Biology Reagents

Evaluation of immunological responses to third COVID-19 vaccine among people treated with sphingosine receptor-1 modulators and anti-CD20 therapy

Authors: Ilana Katz Sand, Sacha Gnjatic, Florian Krammer, Kevin Tuballes, Juan Manuel Carreño, Sammita Satyanarayan, Susan Filomena, Erin Staker, Johnstone Tcheou, Aaron Miller, Michelle Fabian, Neha Safi, Jamie Nichols, Jasmin Patel, Stephen Krieger, Stephanie Tankou, Sam Horng, Sylvia Klineova, Erin Beck, Miriam Merad, Fred Lublin

Journal: Mult Scler Relat Disord

PubMed ID: 36628884

Doi: 10.1016/j.msard.2022.104486

Products & Services: Molecular Biology Reagents

Upconversion nanoparticle-based optogenetic nanosystem for photodynamic therapy and cascade gene therapy

Authors: Xinyue Song, Fengyan Li, Feng Tian, Linlin Ren, Qi Wang, Chengfang Jiang, Tao Yan, Shusheng Zhang

Journal: Acta Biomater

PubMed ID: 36494007

Doi: 10.1016/j.actbio.2022.12.002

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Potential of a novel flagellin epitope as a broad-spectrum vaccine candidate against enteric fever

Authors: Shania Vij, Reena Thakur, Laxmi Kumari, Chander Raman Suri, Praveen Rishi

Journal: Microb Pathog

PubMed ID: 36494021

Doi: 10.1016/j.micpath.2022.105936

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Proteolytic activation of human-specific Olduvai domains by the furin protease

Authors: Ashley Pacheco, Aaron Issaian, Jonathan Davis, Nathan Anderson, Travis Nemkov, Natasia Paukovich, Morkos A Henen, Beat Vögeli, James M Sikela, Kirk Hansen

Journal: Int J Biol Macromol

PubMed ID: 36581038

Doi: 10.1016/j.ijbiomac.2022.12.260

Products & Services: Proteins, Expression, Isolation and Analysis

Impact of latency-reversing agents on human macrophage physiology

Authors: Laurent Hany, Marc-Olivier Turmel, Corinne Barat, Michel Ouellet, Michel J Tremblay

Journal: Immun Inflamm Dis

PubMed ID: 36480653

Doi: 10.1002/iid3.590

Products & Services: Proteins, Expression, Isolation and Analysis

Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics

Authors: Changrong Shi , Qianyu Zhang , Yuying Yao , Fantian Zeng , Chao Du , Sureya Nijiati , Xuejun Wen , Xinyi Zhang , Hongzhang Yang , Haoting Chen , Zhide Guo , Xianzhong Zhang , Jinhao Gao , Weisheng Guo , Xiaoyuan Chen , Zijian Zhou

Journal: Nat Nanotechnol

PubMed ID: 36536041

Doi: 10.1038/s41565-022-01261-7

Products & Services: Recombinant Proteins

Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss

Authors: Alma S Popescu, Claire A Butler, David H Allendorf, Thomas M Piers, Anna Mallach, Julian Roewe, Peter Reinhardt, Alessandro Cinti, Loredana Redaelli, Christophe Boudesco, Laurent Pradier, Jennifer M Pocock, Peter Thornton, Guy C Brown

Journal: Glia

PubMed ID: 36480007

Doi: 10.1002/glia.24318

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Combining intramuscular and intranasal homologous prime-boost with a chimpanzee adenovirus-based COVID-19 vaccine elicits potent humoral and cellular immune responses in mice

Authors: Xingxing Li , Ling Wang , Jingjing Liu , Enyue Fang , Xiaohui Liu , Qinhua Peng , Zelun Zhang , Miao Li , Xinyu Liu , Xiaohong Wu , Danhua Zhao , Lihong Yang , Jia Li , Shouchun Cao , Yanqiu Huang , Leitai Shi , Hongshan Xu , Yunpeng Wang , Yue Suo , Guangzhi Yue , Jianhui Nie , Weijin Huang , Wenjuan Li , Yuhua Li

Journal: Emerg Microbes Infect

PubMed ID: 35775819

Doi: 10.1080/22221751.2022.2097479

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A frontline, rapid, nucleic acid-based Fusarium circinatum detection system using CRISPR/Cas12a combined with recombinase polymerase amplification

Authors: Zhenpeng Chen , Xiao Yang , Hongming Xia , Cuiping Wu , Jing Yang , Tingting Dai

Journal: Plant Dis

PubMed ID: 36480733

Doi: 10.1094/PDIS-05-22-1234-RE

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Mitochondrial GPAT-derived LPA controls auxin-dependent embryonic and postembryonic development

Authors: Qianru Jia , Yang Bai , Hui Xu , Qingyun Liu , Wenyan Li , Teng Li , Feng Lin , Like Shen , Wei Xuan , Wenhua Zhang , Qun Zhang

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36454754

Doi: 10.1073/pnas.2212881119

Products & Services: Proteins, Expression, Isolation and Analysis

clbP Gene, a Potential New Member of the -Lactamase Family

Authors: Adel Azour , Charbel Al-Bayssari , Lucile Pinault , Saïd Azza , Jean-Marc Rolain ,Seydina M. Diene

Journal: Int. J. Mol. Sci

Doi: ijms232415642

Products & Services: Gene Synthesis

Bazi Bushen capsule attenuates cognitive deficits by inhibiting microglia activation and cellular senescence

Authors: Chuanyuan Ji, Cong Wei, Mengnan Li, Shuang Shen, Shixiong Zhang, Yunlong Hou, Yiling Wu

Journal: Pharm Biol

PubMed ID: 36263579

Doi: 10.1080/13880209.2022.2131839

Products & Services: Proteins, Expression, Isolation and Analysis

EYFP fusions to HD-Zip IV transcription factors enhance their stability and lead to phenotypic changes in

Authors: Bibek Subedi, Kathrin Schrick

Journal: Plant Signal Behav

PubMed ID: 36154907

Doi: 10.1080/15592324.2022.2119013

Products & Services: Proteins, Expression, Isolation and Analysis

Design of a H O -generating P450 fusion protein for high yield fatty acid conversion

Authors: Daniele Giuriato, Danilo Correddu, Gianluca Catucci, Giovanna Di Nardo, Cristiano Bolchi, Marco Pallavicini, Gianfranco Gilardi

Journal: Protein Sci

PubMed ID: 36334042

Doi: 10.1002/pro.4501

Products & Services: Plasmid DNA Preparation

A Recombinant Genotype I Japanese Encephalitis Virus Expressing a Gaussia Luciferase Gene for Antiviral Drug Screening Assay and Neutralizing Antibodies Detection

Authors: Chenxi Li , Xuan Chen , Jingbo Hu , Daoyuan Jiang , Demin Cai , Yanhua Li

Journal: Int J Mol Sci

PubMed ID: 36555192

Doi: 10.3390/ijms232415548

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Hepatic neddylation deficiency triggers fatal liver injury via inducing NF-κB-inducing kinase in mice

Authors: Cheng Xu , Hongyi Zhou , Yulan Jin , Khushboo Sahay , Anna Robicsek , Yisong Liu , Kunzhe Dong , Jiliang Zhou , Amanda Barrett , Huabo Su , Weiqin Chen

Journal: Nat Commun

PubMed ID: 36526632

Doi: 10.1038/s41467-022-35525-6

Products & Services: Synthetic sgRNA and crRNA Service Plasmid DNA Preparation

A Rapid Label-Free Disposable Electrochemical Salivary Point-of-Care Sensor for SARS-CoV-2 Detection and Quantification

Authors: Nadia Farsaeivahid, Christian Grenier, Sheyda Nazarian, Ming L Wang

Journal: Sensors (Basel)

PubMed ID: 36617031

Doi: 10.3390/s23010433

Products & Services: Proteins, Expression, Isolation and Analysis

Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape

Authors: Roberta Marzi, Jessica Bassi, Chiara Silacci-Fregni, Istvan Bartha, Francesco Muoio, Katja Culap, Nicole Sprugasci, Gloria Lombardo, Christian Saliba, Elisabetta Cameroni, Antonino Cassotta, Jun Siong Low, Alexandra C Walls, Matthew McCallum, M Alejandra Tortorici, John E Bowen, Exequiel A Dellota, Josh R Dillen, Nadine Czudnochowski, Laura Pertusini, Tatiana Terrot, Valentino Lepori, Maciej Tarkowski, Agostino Riva, Maira Biggiogero, Alessandra Franzetti-Pellanda, Christian Garzoni, Paolo Ferrari, Alessandro Ceschi, Olivier Giannini, Colin Havenar-Daughton, Amalio Telenti, Ann Arvin, Herbert W Virgin, Federica Sallusto, David Veesler, Antonio Lanzavecchia, Davide Corti, Luca Piccoli

Journal: iScience

PubMed ID: 36507220

Doi: 10.1016/j.isci.2022.105726

Products & Services: Molecular Biology Reagents

Human Dectin-1 is -glycosylated and serves as a ligand for C-type lectin receptor CLEC-2

Authors: Shojiro Haji, Taiki Ito, Carla Guenther, Miyako Nakano, Takashi Shimizu, Daiki Mori, Yasunori Chiba, Masato Tanaka, Sushil K Mishra, Janet A Willment, Gordon D Brown, Masamichi Nagae, Sho Yamasaki

Journal: Elife

PubMed ID: 36479973

Doi: 10.7554/eLife.83037

Products & Services: Synthetic sgRNA and crRNA Service

Intracavitary adoptive transfer of IL-12 mRNA-engineered tumor-specific CD8 T cells eradicates peritoneal metastases in mouse models

Authors: Claudia Augusta Di Trani, Assunta Cirella, Leire Arrizabalaga, Ángela Bella, Myriam Fernandez-Sendin, Joan Salvador Russo-Cabrera, Celia Gomar, Irene Olivera, Elizabeth Bolaños, José González-Gomariz, Maite Álvarez, Iñaki Etxeberria, Belen Palencia, Álvaro Teijeira, Ignacio Melero, Pedro Berraondo, Fernando Aranda

Journal: Oncoimmunology

PubMed ID: 36531687

Doi: 10.1080/2162402X.2022.2147317

Products & Services: Combinatorial DNA Libraries

Unsterile production of a polyhydroxyalkanoate copolymer by Halomonas cupida J9

Authors: Yujie Liu, Wanwan Zhao, Siqi Wang, Kaiyue Huo, Yaping Chen, Hongfu Guo, Shufang Wang, Ruihua Liu, Chao Yang

Journal: Int J Biol Macromol

PubMed ID: 36347367

Doi: 10.1016/j.ijbiomac.2022.10.275

Products & Services: Bacterial Expression

Amelioration of ethanol-induced oxidative stress and alcoholic liver disease by in vivo RNAi targeting Cyp2e1

Authors: Yalan Wang, Qiubing Chen, Shuang Wu, Xinyu Sun, Runting Yin, Zhen Ouyang, Hao Yin, Yuan Wei

Journal: Acta Pharmaceutica Sinica B

Doi: 10.1016/j.apsb.2023.01.009

Products & Services: Custom DNA/RNA Oligos

Brown goat yogurt: Metabolomics, peptidomics, and sensory changes during production

Authors: R Zhang, W Jia

Journal: J Dairy Sci

PubMed ID: 36586795

Doi: 10.3168/jds.2022-22654

Products & Services: Peptide Synthesis

Cell membrane-camouflaged liposomes and neo-peptide-loaded liposomes with TLR agonist R848 provides a prime and boost strategy for efficient personalized cancer vaccine therapy

Authors: Lu Shi , Hongchen Gu

Journal: Nanomedicine

PubMed ID: 36584738

Doi: 10.1016/j.nano.2022.102648

Products & Services: Peptide Synthesis

An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo

Authors: Yajing Zhao , Ningbo Zhao, Yanxing Cai , Hui Zhang, Jia Li, Jiaqi Liu , Chuantao Ye , Yuan Wang , Yamei Dang , Wanying Li , He Liu , Lianqing Zhang , Yuexiang Li , Liang Zhang , Linfeng Cheng , Yangchao Dong , Zhikai Xu , Yingfeng Lei , Lu Lu , Yingjuan Wang , Wei Ye , Fanglin Zhang

Journal: Front Cell Infect Microbiol .

PubMed ID: 36579342

Doi: 10.3389/fcimb.2022.881083

Products & Services: Gene Services

Neutraligands of C5a can potentially occlude the interaction of C5a with the complement receptors C5aR1 and C5aR2

Authors: Aurosikha Das, Manaswini Ghosh, Pulkit Kr Gupta, Soumendra Rana

Journal: J Cell Biochem

PubMed ID: 36565188

Doi: 10.1002/jcb.30360

Products & Services: Peptide Synthesis

Pseudomonas aeruginosa Promotes Persistence of Stenotrophomonas maltophilia via Increased Adherence to Depolarized Respiratory Epithelium

Authors: Melissa S McDaniel, Natalie R Lindgren, Caitlin E Billiot, Kristina N Valladares, Nicholas A Sumpter, W Edward Swords

Journal: Microbiol Spectr

PubMed ID: 36472421

Doi: 10.1128/spectrum.03846-22

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A chromosome-level genome assembly reveals that tandem-duplicated CYP706V oxidase genes control oridonin biosynthesis in the shoot apex of Isodon rubescens

Authors: Yuwei Sun, Jie Shao, Haili Liu, Hua Wang, Guangyi Wang, Jianhua Li, Yaping Mao, Zhuo Chen, Ke Ma, Lin Xu, Yong Wang

Journal: Mol Plant

PubMed ID: 36518072

Doi: 10.1016/j.molp.2022.12.007

Products & Services: Gene Synthesis

Molecular cloning and functional characterization of melanocortin-3 receptor in grass carp (Ctenopharyngodon idella)

Authors: Haolin Mo, Huixia Yu, Yang Li, Timothy P C Ezeorba, Zhihao Zhang, Mingxin Yao, Jiajia Yu, Dongmei Xiong, Haixia Liu, Lixin Wang

Journal: Fish Physiol Biochem

PubMed ID: 36547499

Doi: 10.1007/s10695-022-01164-3

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Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation

Authors: Zhouping Hong , Jyoti Adlakha , Neng Wan , Emily Guinn , Fabian Giska , Kallol Gupta , Thomas J Melia , Karin M Reinisch

Journal: J Cell Biol .

PubMed ID: 36282247

Doi: 10.1083/jcb.202207022

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An auristatin-based peptide-drug conjugate targeting Kita-Kyushu lung cancer antigen 1 for precision chemoradiotherapy in gastric cancer

Authors: Xiaotong Chen , Fangcen Liu , Xiaoxiao Yu , Lin Li , Jiayao Yan , Xinjie Chen , Qin Liu , Baorui Liu

Journal: Eur J Med Chem

PubMed ID: 35932567

Doi: 10.1016/j.ejmech.2022.114617

Products & Services: Recombinant Antibody Expression

Independently evolved viral effectors convergently suppress DELLA protein SLR1-mediated broad-spectrum antiviral immunity in rice

Authors: Lulu Li , Hehong Zhang , Zihang Yang , Chen Wang , Shanshan Li , Chen Cao , Tongsong Yao , Zhongyan Wei , Yanjun Li , Jianping Chen , Zongtao Sun

Journal: Nat Commun

PubMed ID: 36376330

Doi: doi.org/10.1038/s41467-022-34649-z

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Optimized prime editing in monocot plants using PlantPegDesigner and engineered plant prime editors (ePPEs)

Authors: Shuai Jin , Qiupeng Lin , Qiang Gao , Caixia Gao

Journal: Nat Protoc

PubMed ID: 36434096

Doi: doi.org/10.1038/s41596-022-00773-9

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A gold nanoparticles-based lateral flow assay utilizing baculovirus expressed recombinant nucleocapsid and receptor binding domain proteins for serodetection of IgG and IgM against SARS-CoV-2

Authors: Reda Salem, Amany M Elshamy, Noha Kamel, Soha Younes, Ohoud M Marie, Fatma R Waly, Alaa A El-Kholy, Wael Elmenofy

Journal: Biotechnol Lett

PubMed ID: 36319880

Doi: 10.1007/s10529-022-03316-0

Products & Services: Mammalian Expression

Neutralization Epitopes in Trimer and Pentamer Complexes Recognized by Potent Cytomegalovirus-Neutralizing Human Monoclonal Antibodies

Authors: Yuanbao Ai, Changwen Wu, Ming Zhang, Dabbu Kumar Jaijyan, Tong Liu, Lipeng Zan, Nan Li, Wei Yu, Yueming Wang, Xiaohui Yuan, Chengming Li, Weihong Zheng, Hua Zhu, Hua-Xin Liao

Journal: Microbiol Spectr

PubMed ID: 36342276

Doi: 10.1128/spectrum.01393-22

Products & Services: Proteins, Expression, Isolation and Analysis

Seroprevalence of AAV neutralizing antibodies in males with Duchenne muscular dystrophy

Authors: Sumit Verma, Stella N Nwosu, Raj Razdan, Saila R Upadhyayula, Han C Phan, Abubakarr A Koroma, Isai Leguizamo, Natalie S Correa, Michael Kuipa, David Lee, Thomas H Vanderford, Matthew R Gardner

Journal: Hum Gene Ther

PubMed ID: 36324212

Doi: 10.1089/hum.2022.081

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The two Gtsf paralogs in silkworms orthogonally activate their partner PIWI proteins for target cleavage

Authors: Natsuko Izumi, Keisuke Shoji, Takashi Kiuchi, Susumu Katsuma, Yukihide Tomari

Journal: RNA

PubMed ID: 36319089

Doi: 10.1261/rna.079380.122

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Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation

Authors: Eisho Kanemitsu, Xiangdong Zhao, Keiko Iwaisako, Asuka Inoue, Akihide Takeuchi, Shintaro Yagi, Hidetoshi Masumoto, Hiroaki Ohara, Motoyasu Hosokawa, Tomonari Awaya, Junken Aoki, Etsuro Hatano, Shinji Uemoto, Masatoshi Hagiwara

Journal: Transl Res

PubMed ID: 36347491

Doi: 10.1016/j.trsl.2022.11.003

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IgA quantification as a good predictor of the neutralizing antibodies levels after vaccination against SARS-CoV-2

Authors: Lorena O Fernandes-Siqueira, Bruna G Sousa, Carlos E Cleto, Luciana S Wermelinger, Beatriz L L Caetano, Agatha R Pacheco, Simone M Costa, Fabio C L Almeida, Gustavo C Ferreira, Didier Salmon, Ada M B Alves, Andrea T Da Poian

Journal: J Clin Virol Plus

PubMed ID: 36349309

Doi: 10.1016/j.jcvp.2022.100121

Development of fluorescent peptide G protein-coupled receptor activation biosensors for NanoBRET characterization of intracellular allosteric modulators

Authors: James P Farmer, Shailesh N Mistry, Charles A Laughton, Nicholas D Holliday

Journal: FASEB J

PubMed ID: 36183332

Doi: 10.1096/fj.202201024R

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A human adenovirus encoding IFN-γ can transduce Tasmanian devil facial tumour cells and upregulate MHC-I

Authors: Ahab N Kayigwe, Jocelyn M Darby, A Bruce Lyons, Amanda L Patchett, Leszek Lisowski, Guei-Sheung Liu, Andrew S Flies

Journal: J Gen Virol

PubMed ID: 36382885

Doi: 10.1099/jgv.0.001812

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Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies

Authors: Nadeem Murtaza, Annie A Cheng, Chad O Brown, Durga Praveen Meka, Shuai Hong, Jarryll A Uy, Joelle El-Hajjar, Neta Pipko, Brianna K Unda, Birgit Schwanke, Sansi Xing, Bhooma Thiruvahindrapuram, Worrawat Engchuan, Brett Trost, Eric Deneault, Froylan Calderon de Anda, Bradley W Doble, James Ellis, Evdokia Anagnostou, Gary D Bader, Stephen W Scherer, Yu Lu, Karun K Singh

Journal: Cell Rep

PubMed ID: 36417873

Doi: 10.1016/j.celrep.2022.111678

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TMT-Based Comparative Peptidomics Analysis of Rice Seedlings under Salt Stress: An Accessible Method to Explore Plant Stress-Tolerance Processing

Authors: Wanlu Ma, Chenchen Zhang, Wei Zhang, Pijie Sheng, Minyan Xu, Ying Ni, Meng Chen, Beijiu Cheng, Xin Zhang

Journal: J Proteome Res

PubMed ID: 36351196

Doi: 10.1021/acs.jproteome.2c00318

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Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals

Authors: Keisuke Fukuchi, Kayoko Nanai, Hiroshi Yuita, Chikako Maru, Jun Tsukada, Masato Ishigami, Yoko Nagai, Yoko Nakano, Chigusa Yoshimura, Kozo Yoneda, Masato Amano, Kensuke Nakamura, Yoko Oda, Haruyuki Nishigohri, Shoji Yamamoto, Yusuke Ohnishi-Totoki, Koichiro Inaki, Hironobu Komori, Rika Nakano, Yoshiyuki Kanari, Atsuko Nishida, Yumi Matsui, Satoko Funo, Sayako Takahashi, Toshiaki Ohtsuka, Toshinori Agatsuma

Journal: J Oncol

PubMed ID: 36385956

Doi: 10.1155/2022/3552793

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Recombinant Vaccinia Virus Expressing Apical Membrane Antigen 1 or Microneme Protein Enhances Protection against Infection in Mice

Authors: Min-Ju Kim, Ki-Back Chu, Su-Hwa Lee, Hae-Ji Kang, Keon-Woong Yoon, Md Atique Ahmed, Fu-Shi Quan

Journal: Trop Med Infect Dis

PubMed ID: 36355892

Doi: 10.3390/tropicalmed7110350

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Accelerated Polyethylene Terephthalate (PET) Enzymatic Degradation by Room Temperature Alkali Pre-treatment for Reduced Polymer Crystallinity

Authors: Sariah Giraldo-Narcizo, Nihal Guenani, Ana María Sánchez-Pérez, Antonio Guerrero

Journal: Chembiochem

PubMed ID: 36341520

Doi: 10.1002/cbic.202200503

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Intrinsically Unstructured Sequences in the mRNA 3' UTR Reduce the Ability of Poly(A) Tail to Enhance Translation

Authors: Wan-Jung C Lai, Mingyi Zhu, Margarita Belinite, Gregory Ballard, David H Mathews, Dmitri N Ermolenko

Journal: J Mol Biol

PubMed ID: 36368412

Doi: 10.1016/j.jmb.2022.167877

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Multivalent binding of the hub protein LC8 at a newly discovered site in 53BP1

Authors: Jesse Howe, Austin Weeks, Patrick Reardon, Elisar Barbar

Journal: Biophys J

PubMed ID: 36335430

Doi: 10.1016/j.bpj.2022.11.006

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