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Cellular and humoral immunity to Ebola Zaire glycoprotein and viral vector proteins following immunization with recombinant vesicular stomatitis virus-based Ebola vaccine (rVSVΔG-ZEBOV-GP)

Authors: Vanessa Raabe, Lilin Lai, Juliet Morales, Yongxian Xu, Nadine Rouphael, Richard T Davey, Mark J Mulligan

Journal: Vaccine

PubMed ID: 36725433

Doi: 10.1016/j.vaccine.2023.01.059

Products & Services: Peptide Synthesis

Design of a chimeric ACE-2/Fc-silent fusion protein with ultrahigh affinity and neutralizing capacity for SARS-CoV-2 variants

Authors: Neil M Bodie, Rina Hashimoto, David Connolly, Jennifer Chu, Kazuo Takayama, Bruce D Uhal

Journal: Antib Ther

PubMed ID: 36741194

Doi: 10.1093/abt/tbad001

Products & Services: Proteins, Expression, Isolation and Analysis

Cry51Aa Proteins Are Active against and Show a Mechanism Similar to Pore Formation Model

Authors: Ei Thinzar Soe, Zaw Lin Naing, Caihong Zhang, Lin Lin Niu, Jinrong Tang, Siqi Yu, Zhongwei Ding, Gemei Liang

Journal: J Agric Food Chem

PubMed ID: 36710440

Doi: 10.1021/acs.jafc.2c07244

Products & Services: Proteins, Expression, Isolation and Analysis

Simultaneous enzyme production, Levan-type FOS synthesis and sugar by-products elimination using a recombinant Pichia pastoris strain expressing a levansucrase-endolevanase fusion enzyme

Authors: Ángela Ávila-Fernández, Silvia Montiel, María Elena Rodríguez-Alegría, Luis Caspeta, Agustín López Munguía

Journal: Microb Cell Fact

PubMed ID: 36703199

Doi: 10.1186/s12934-022-02009-7

Products & Services: Molecular Biology Reagents

Structure of monkeypox virus DNA polymerase holoenzyme

Authors: Qi Peng, Yufeng Xie, Lu Kuai, Han Wang, Jianxun Qi, George F Gao, Yi Shi

Journal: Science (New York, N. Y.)

PubMed ID: 36520947

Doi: 10.1126/science.ade6360

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Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis

Authors: Alhaji H. Janneh, Mohamed Faisal Kassir, F. Cansu Atilgan, Stephen Tomlinson, Shikhar Mehrotra, Besim Ogretmen

Journal: Cell Reports

Doi: doi.org/10.1016/j.celrep.2022.111742

Products & Services: Catalog Antibody Plasmid DNA Preparation

Structure-activity relationship studies for inhibitors for vancomycin-resistant and human carbonic anhydrases

Authors: Weiwei An, Katrina J Holly, Alessio Nocentini, Ryan D Imhoff, Chad S Hewitt, Nader S Abutaleb, Xufeng Cao, Mohamed N Seleem, Claudiu T Supuran, Daniel P Flaherty

Journal: J Enzyme Inhib Med Chem

PubMed ID: 35758212

Doi: 10.1080/14756366.2022.2092729

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Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A

Authors: Dell'Orco D, Dal Cortivo G.

Journal: Sci Rep

PubMed ID: 31882816

Doi: 10.1038/s41598-019-56606-5

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SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugate

Authors: Alexander J Garvin , Alexander J Lanz , Joanna R Morris

Journal: Sci Rep

PubMed ID: 36494414

Doi: 10.1038/s41598-022-25665-6

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Prevalence of Anti-PF4 Antibodies After First and Second ChAdOx1 nCoV-19 Vaccinations in Women With Adverse Events: A Brief Report and Literature Review

Authors: Kye Won Choe, Yong Kwan Lim, Oh Joo Kweon, Mi-Kyung Lee, Jin-Won Chung, Hye Ryoun Kim

Journal: Ann Lab Med

PubMed ID: 36544343

Doi: 10.3343/alm.2023.43.3.299

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of selective hepatitis delta virus ribozyme inhibitors by high-throughput screening of small molecule libraries

Authors: Eirini D Tseligka, Stéphanie Conzelmann, Yves Cambet, Tifany Schaer, Francesco Negro, Sophie Clément

Journal: JHEP Rep

PubMed ID: 36704052

Doi: 10.1016/j.jhepr.2022.100652

Products & Services: Proteins, Expression, Isolation and Analysis

Influence of affinity tags and tobacco PR1a signal peptide on detection, purification and bioactivity analyses of the small oomycete apoplastic effectors

Authors: Jing-Hao Jin, Xue Zhou, Wang Liu, Zi-Hui Zhang, Shen-Xin Huang, Wen-Jing Zhao, Xiao-Ren Chen

Journal: Biotechnol Lett

PubMed ID: 36450976

Doi: 10.1007/s10529-022-03324-0

Products & Services: Molecular Biology Reagents

Development of a cockroach (Blattella germanica) qPCR for the objective measurement of exposure at home

Authors: Steffi Rocchi, Benoit Valot, Audrey Laboissière, Audrey Guitton, Emeline Scherer, Laurence Millon, Gabriel Reboux

Journal: Sci Total Environ

PubMed ID: 36526200

Doi: 10.1016/j.scitotenv.2022.160965

Products & Services: Molecular Biology Reagents

BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network

Authors: Xueqin Sun, Olaf Klingbeil, Bin Lu, Caizhi Wu, Carlos Ballon, Meng Ouyang, Xiaoli S Wu, Ying Jin, Yon Hwangbo, Yu-Han Huang, Tim D D Somerville, Kenneth Chang, Jung Park, Taemoon Chung, Scott K Lyons, Junwei Shi, Hannes Vogel, Michael Schulder, Christopher R Vakoc, Alea A Mills

Journal: Nature

PubMed ID: 36544023

Doi: 10.1038/s41586-022-05551-x

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Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA

Authors: Seow Neng Chan, Jun Wei Pek

Journal: EMBO Rep

PubMed ID: 36533631

Doi: 10.15252/embr.202154350

Products & Services: Stable Cell Lines

The effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple

Authors: Runmin Che, Changhai Liu, Qi Wang, Wenyan Tu, Ping Wang, Chao Li, Xiaoqing Gong, Ke Mao, Hao Feng, Lili Huang, Pengmin Li, Fengwang Ma

Journal: Autophagy

PubMed ID: 36449354

Doi: 10.1080/15548627.2022.2153573

Products & Services: Proteins, Expression, Isolation and Analysis

Tissue replication and mucosal swab detection of Sosuga virus in Syrian hamsters in the absence of overt tissue pathology and clinical disease

Authors: Stephen R Welch, Jana M Ritter, Amy J Schuh, Sarah C Genzer, Teresa E Sorvillo, Jessica R Harmon, JoAnn D Coleman-McCray, Shilpi Jain, Punya Shrivastava-Ranjan, Josilene Nascimento Seixas, Lindsey B Estetter, Pamela S Fair, Jonathan S Towner, Joel M Montgomery, César G Albariño, Christina F Spiropoulou, Jessica R Spengler

Journal: Antiviral Res

PubMed ID: 36521633

Doi: 10.1016/j.antiviral.2022.105490

Products & Services: Proteins, Expression, Isolation and Analysis

Roles of the transcriptional regulators Fts1, YlNrg1, YlTup1, and YlSsn6 in the repression of the yeast-to-filament transition in the dimorphic yeast Yarrowia lipolytica

Authors: Yi-Sheng Mao, Jia-Wen Chen, Zhen-Hua Wang, Meng-Yang Xu, Xiang-Dong Gao

Journal: Mol Microbiol

PubMed ID: 36537557

Doi: 10.1111/mmi.15017

Products & Services: Molecular Biology Reagents

Functional recovery of myocardial infarction by specific EBP-PR1P peptides bridging injectable cardiac extracellular matrix and vascular endothelial growth factor

Authors: Wenxuan Cao, Hong Zhang, Ning Zhou, Runxue Zhou, Xiaojing Zhang, Jia Yin, Jin Deng, Xiang Ao, Chunying Shi

Journal: J Biomed Mater Res A

PubMed ID: 36579729

Doi: 10.1002/jbm.a.37483

Products & Services: Peptide Synthesis

Cadmium chloride exposure impairs the growth and behavior of Drosophila via ferroptosis

Authors: Yingxia Hu, Haijie Wu, Chenying Lu, Hanqing Xu, Boyang Li, Wanchun Guan, Mingjiang Wu, Yitian Gao, Haibin Tong

Journal: Sci Total Environ

PubMed ID: 36581278

Doi: 10.1016/j.scitotenv.2022.161183

Products & Services: Molecular Biology Reagents

Polymyxin B neutralizes endotoxin and improves the quality of chicken semen during liquid storage

Authors: Ei Ei Win Maung, Pangda Sopha Sushadi, Atsushi Asano

Journal: Theriogenology

PubMed ID: 36577162

Doi: 10.1016/j.theriogenology.2022.12.027

Products & Services: Molecular Biology Reagents

Electrical stimulation of piezoelectric BaTiO3 coated Ti6Al4V scaffolds promote antiinflammatory polarization of macrophage and bone repair via MAPK/JNK inhibition and OXPHOS activation

Authors: Hao Wu, Dong Hui, Zhen Tang, Yu Chen, Yichao Liu, Mo Wang, Xinghui Wei, Ning Wang, Shusen Bao, Dongmei Yu, Zhigang Wu, Zhenda Yang, Xiaokang Li, Zheng Guo, Lei Shi

Journal: Biomaterials

Doi: 10.1016/j.biomaterials.2022.121990

Products & Services: Proteins, Expression, Isolation and Analysis

mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

Authors: Clifford T H Hayashi , Yi Cao , Leor C Clark , Abhai K Tripathi , Fidel Zavala , Garima Dwivedi , James Knox , Mohamad-Gabriel Alameh , Paulo J C Lin , Ying K Tam , Drew Weissman , Nirbhay Kumar

Journal: NPJ Vaccines

PubMed ID: 36456563

Doi: 10.1038/s41541-022-00577-8

Products & Services: Codon Optimization

LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway

Authors: Uttam Sharma, Manjit Kaur Rana, Karuna Singh, Aklank Jain

Journal: Biochem Pharmacol

PubMed ID: 36493845

Doi: 10.1016/j.bcp.2022.115372

Products & Services: Molecular Biology Reagents

A BioBricks Metabolic Engineering Platform for the Biosynthesis of Anthracyclinones in Streptomyces coelicolor

Authors: Rongbin Wang , Jennifer Nguyen , Jacob Hecht , Nora Schwartz , Katelyn V Brown , Larissa V Ponomareva, Magdalena Niemczura , Dino van Dissel , Gilles P van Wezel , Jon S Thorson, Mikko Metsä-Ketelä , Khaled A Shaaban, S Eric Nybo

Journal: ACS Synth Biol

PubMed ID: 36378506

Doi: 10.1021/acssynbio.2c00498

Products & Services: Gene Synthesis

An epitope-directed selection strategy facilitating the identification of Frizzled receptor selective antibodies

Authors: Qiangqiang Ge, Maikun Teng, Xu Li, Qiong Guo, Yuyong Tao

Journal: Structure

PubMed ID: 36513066

Doi: 10.1016/j.str.2022.11.009

Products & Services: Proteins, Expression, Isolation and Analysis

DNA-protein cross-links between abasic DNA damage and mitochondrial transcription factor A (TFAM)

Authors: Wenyan Xu , Jin Tang , Linlin Zhao

Journal: Nucleic Acids Res

PubMed ID: 36583367

Doi: 10.1093/nar/gkac1214

Products & Services: Catalog Antibody

Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling

Authors: Bärbel Schröfelbauer, Patrick K Kimes, Paige Hauke, Charlotte E Reid, Kevin Shao, Sarah J Hill, Rafael Irizarry, William C Hahn

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36574667

Doi: 10.1073/pnas.2206751120

Products & Services: Proteins, Expression, Isolation and Analysis

Principles of mitoribosomal small subunit assembly in eukaryotes

Authors: Nathan J Harper, Chloe Burnside, Sebastian Klinge

Journal: Nature

PubMed ID: 36482135

Doi: 10.1038/s41586-022-05621-0

Products & Services: Gene Synthesis

Antibody Response of Heterologous vs Homologous Messenger RNA Vaccine Boosters Against the Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant: Interim Results from the PRIBIVAC Study, a Randomized Clinical Trial

Authors: Xuan Ying Poh, Chee Wah Tan, I Russel Lee, Jean-Marc Chavatte, Siew-Wai Fong, Tessa Prince, Catherine Hartley, Aileen Y Y Yeoh, Suma Rao, Po Ying Chia, Sean W X Ong, Tau Hong Lee, Sapna P Sadarangani, Ray J H Lin, Clarissa Lim, Jefanie Teo, Daniel R X Lim, Wanni Chia, Julian A Hiscox, Lisa F P Ng, Ee Chee Ren, Raymond T P Lin, Laurent Renia, David Chien Lye, Lin-Fa Wang, Barnaby E Young

Journal: Clin Infect Dis

PubMed ID: 35543372

Doi: 10.1093/cid/ciac345

Products & Services: Recombinant Proteins

Early TNF-Dependent Regulation of Excitatory and Inhibitory Synapses on Striatal Direct Pathway Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease

Authors: Julien Chambon, Pragya Komal, Gil M Lewitus, Gina M Kemp, Simone Valade, Houaria Adaïdi, Noura Al Bistami, David Stellwagen

Journal: J Neurosci

PubMed ID: 36517241

Doi: 10.1523/JNEUROSCI.1655-22.2022

Products & Services: Molecular Biology Reagents

Long-Term Adaptation to Galactose as a Sole Carbon Source Selects for Mutations Outside the Canonical GAL Pathway

Authors: Artemiza A Martínez, Andrew Conboy, Sean W Buskirk, Daniel A Marad, Gregory I Lang

Journal: J Mol Evol

PubMed ID: 36482210

Doi: 10.1007/s00239-022-10079-9

Products & Services: Proteins, Expression, Isolation and Analysis

Disease modification and symptom relief in osteoarthritis using a mutated GCP-2/CXCL6 chemokine

Authors: Sara Caxaria, Nikolaos Kouvatsos, Suzanne E Eldridge, Mario Alvarez-Fallas, Anne-Sophie Thorup, Daniela Cici, Aida Barawi, Ammaarah Arshed, Danielle Strachan, Giulia Carletti, Xinying Huang, Sabah Bharde, Melody Deniz, Jacob Wilson, Bethan L Thomas, Costantino Pitzalis, Francesco Paolo Cantatore, Manasi Sayilekshmy, Shafaq Sikandar, Frank P Luyten, Thomas Pap, Joanna C Sherwood, Anthony J Day, Francesco Dell'Accio

Journal: EMBO Mol Med

PubMed ID: 36507558

Doi: 10.15252/emmm.202216218

Products & Services: Molecular Biology Reagents

Comment on: Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage

Authors: Luiza H Galarion, Justin E Clarke, Harry Schofield, Alex J O'Neill

Journal: J Antimicrob Chemother

PubMed ID: 36416794

Doi: 10.1093/jac/dkac397

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High-Throughput and Efficient Intracellular Delivery Method via a Vibration-Assisted Nanoneedle/Microfluidic Composite System

Authors: Xuan Li , Yuan Ma , Yu Xue , Xuanhe Zhang , Linwen Lv , Qianghua Quan , Yiqing Chen , Guoxu Yu , Zhenwei Liang , Xinping Zhang , Ding Weng , Lei Chen , Kui Chen , Xin Han , Jiadao Wang

Journal: ACS Nano

PubMed ID: 36479877

Doi: 10.1021/acsnano.2c07852

Products & Services: GenCrispr Cas9 Genome Editing Synthetic sgRNA and crRNA Service

Mir204 and Mir211 suppress synovial inflammation and proliferation in rheumatoid arthritis by targeting Ssrp1

Authors: Qi-Shan Wang , Kai-Jian Fan, Hui Teng , Sijia Chen , Bing-Xin Xu, Di Chen, Ting-Yu Wang

Journal: Elife

Doi: doi.org/10.7554/eLife.78085

Products & Services: Proteins, Expression, Isolation and Analysis

Intranasal bovine β-defensin-5 enhances antituberculosis immunity in a mouse model by a novel protein-based respiratory mucosal vaccine

Authors: Zhengmin Liang, Hao Li, Mengjin Qu, Yiduo Liu, Yuanzhi Wang, Haoran Wang, Yuhui Dong, Yulan Chen, Xin Ge, Xiangmei Zhou

Journal: Virulence

PubMed ID: 35603910

Doi: 10.1080/21505594.2022.2080342

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Molybdopterin biosynthesis pathway contributes to the regulation of SaeRS two-component system by ClpP in

Authors: Na Zhao, Yanan Wang, Junlan Liu, Ziyu Yang, Ying Jian, Hua Wang, Mahmoud Ahmed, Min Li, Taeok Bae, Qian Liu

Journal: Virulence

PubMed ID: 35481455

Doi: 10.1080/21505594.2022.2065961

Products & Services: Plasmid DNA Preparation

Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants

Authors: Qihong Yan, Ruitian Hou, Xiaohan Huang, Yanjun Zhang, Ping He, Yudi Zhang, Banghui Liu, Qian Wang, Haiyue Rao, Xianying Chen, Xinwei Zhao, Xuefeng Niu, Jincun Zhao, Xiaoli Xiong, Ling Chen

Journal: Emerg Microbes Infect

PubMed ID: 36288106

Doi: 10.1080/22221751.2022.2140611

Products & Services: Proteins, Expression, Isolation and Analysis Gene Synthesis

Unamplified and Real-Time Label-Free miRNA-21 Detection Using Solution-Gated Graphene Transistors in Prostate Cancer Diagnosis

Authors: Minghua Deng, Zhanpeng Ren, Huibin Zhang, Ziqin Li, Chenglong Xue, Jianying Wang, Dan Zhang, Huan Yang, Xianbao Wang, Jinhua Li

Journal: Adv Sci (Weinh)

PubMed ID: 36480308

Doi: 10.1002/advs.202205886

Products & Services: Proteins, Expression, Isolation and Analysis

Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes

Authors: Jakub Benýšek, Michal Buša, Petra Rubešová, Jindřich Fanfrlík, Martin Lepšík, Jiří Brynda, Zuzana Matoušková, Ulrike Bartz, Martin Horn, Michael Gütschow, Michael Mareš

Journal: J Enzyme Inhib Med Chem

PubMed ID: 35144520

Doi: 10.1080/14756366.2021.2024527

Products & Services: Plasmid DNA Preparation

A De Novo Missense Variant in TUBG2 in a Child with Global Developmental Delay, Microcephaly, Refractory Epilepsy and Perisylvian Polymicrogyria

Authors: Salini Thulasirajah, Xueqi Wang, Erick Sell, Jorge Dávila, David A Dyment, Kristin D Kernohan

Journal: Genes

PubMed ID: 36672848

Doi: 10.3390/genes14010108

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Inhibition of autophagy reduces the rate of fluoride-induced LS8 apoptosis via regulating ATG5 and ATG7

Authors: Lin Zhao, Han Wang, Sijia Liu, Tao Xi, Liyuan Wang, Yang Li, Lu Chen, Ruan Jianping, Kristina Xiao Liang

Journal: J Biochem Mol Toxicol

PubMed ID: 36536498

Doi: 10.1002/jbt.23280

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Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli

Authors: Ashok R Nayak , Pradip K Singh , Jinlei Zhao , Montserrat Samsó , Michael S Donnenberg

Journal: mBio

PubMed ID: 36326250

Doi: 10.1128/mbio.02270-22

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Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis

Authors: Li Ma, Junfeng Wei, Yanli Zeng, Junping Liu, Erhui Xiao, Yuehua Kang, Yi Kang

Journal: Drug Deliv

PubMed ID: 35099348

Doi: 10.1080/10717544.2022.2030428

Products & Services: Proteins, Expression, Isolation and Analysis

Suchilactone inhibits the growth of acute myeloid leukaemia by inactivating SHP2

Authors: Jingjing Wu, Yuan Deng, Xin Zhang, Jingjing Ma, Xinqi Zheng, Yue Chen

Journal: Pharm Biol

PubMed ID: 34962431

Doi: 10.1080/13880209.2021.2017467

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ADAR1 improved Treg cell function through the miR-21b/Foxp3 axis and inhibits the progression of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

Authors: Yanru Zhao, Xiaoyan Zheng, Miaojing Li, Jing Zhao, Xiaoning Wang, Huachao Zhu

Journal: Int Immunopharmacol

PubMed ID: 36577155

Doi: 10.1016/j.intimp.2022.109620

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GmYSL7 controls iron uptake, allocation, and cellular response of nodules in soybean

Authors: Xinying Wu, Yongliang Wang, Qiaohan Ni, Haizhen Li, Xuesong Wu, Zhanxin Yuan, Renhao Xiao, Ziyin Ren, Jingjing Lu, Jinxia Yun, Zhijuan Wang, Xia Li

Journal: J Integr Plant Biol

PubMed ID: 36107150

Doi: 10.1111/jipb.13364

Products & Services: Proteins, Expression, Isolation and Analysis

DeGlyPHER: Highly sensitive site-specific analysis of N-linked glycans on proteins

Authors: Sabyasachi Baboo, Jolene K Diedrich, Salvador Martínez-Bartolomé, Xiaoning Wang, Torben Schiffner, Bettina Groschel, William R Schief, James C Paulson, John R Yates

Journal: Methods Enzymol

PubMed ID: 36948700

Doi: 10.1016/bs.mie.2022.09.004

Products & Services: Proteins, Expression, Isolation and Analysis

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

Authors: Yunlong Cao, Fanchong Jian, Jing Wang, Yuanling Yu, Weiliang Song, Ayijiang Yisimayi, Jing Wang, Ran An, Xiaosu Chen, Na Zhang, Yao Wang, Peng Wang, Lijuan Zhao, Haiyan Sun, Lingling Yu, Sijie Yang, Xiao Niu, Tianhe Xiao, Qingqing Gu, Fei Shao, Xiaohua Hao, Yanli Xu, Ronghua Jin, Zhongyang Shen, Youchun Wang, Xiaoliang Sunney Xie

Journal: Nature

PubMed ID: 36535326

Doi: 10.1038/s41586-022-05644-7

Products & Services: Proteins, Expression, Isolation and Analysis