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Ligand-dependent protein interactions of the juvenile hormone receptor captured in real time

Authors: Sarka Tumova, Marek Jindra

Journal: FEBS J

PubMed ID: 36609881

Doi: 10.1111/febs.16719

Products & Services: Molecular Biology Reagents

Discovery and validation of new Hv1 proton channel inhibitors with onco-therapeutic potential

Authors: Antoun El Chemaly, Vincent Jaquet, Yves Cambet, Aurélie Caillon, Ophélie Cherpin, Alexia Balafa, Karl-Heinz Krause, Nicolas Demaurex

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 36640925

Doi: 10.1016/j.bbamcr.2022.119415

Products & Services: Molecular Biology Reagents

His-tagged lactate oxidase production for industrial applications using fed-batch fermentation

Authors: Agustina Godino, Marilla Amaranto, Agustina Manassero, Fausto Comba, Martín Alonzo Pérez, Lucio Simonella, Martín Pernigotti, José L Barra

Journal: J Biotechnol

PubMed ID: 36608873

Doi: 10.1016/j.jbiotec.2022.12.011

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Protective Effects of against High-Cholesterol Diet-Induced Fatty Liver and Regulation of Host Gene Expression Profiles

Authors: Tianhua He, Nikita Lykov, Xu Luo, Huiling Wang, Zhanxiang Du, Ziyi Chen, Shitian Chen, Lin Zhu, Ye Zhao, Chimeng Tzeng

Journal: Int J Mol Sci

PubMed ID: 36768377

Doi: 10.3390/ijms24032053

Products & Services: Proteins, Expression, Isolation and Analysis

Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation

Authors: Pedro Madrigal, Siwei Deng, Yuliang Feng, Stefania Militi, Kim Jee Goh, Reshma Nibhani, Rodrigo Grandy, Anna Osnato, Daniel Ortmann, Stephanie Brown, Siim Pauklin

Journal: Nat Commun

PubMed ID: 36697417

Doi: 10.1038/s41467-023-36116-9

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Hyaluronate decorated polyethylene glycol linked poly(lactide-co-glycolide) nanoparticles encapsulating MUC-1 peptide augmented mucosal immune response in Balb/c mice through inhalation route

Authors: Kiran Jyoti, Garima Malik, Monika Chaudhary, Jitender Madan, Anjoo Kamboj

Journal: Biochim Biophys Acta Gen Subj

PubMed ID: 36731729

Doi: 10.1016/j.bbagen.2023.130317

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Activity-balanced GLP-1/GDF15 dual agonist reduces body weight and metabolic disorder in mice and non-human primates

Authors: Yuanyuan Zhang, Xinyu Zhao, Xiaona Dong, Yuying Zhang, Haixia Zou, Yaoguang Jin, Wei Guo, Peng Zhai, Xu Chen, Alexei Kharitonenkov

Journal: Cell Metab

PubMed ID: 36706758

Doi: 10.1016/j.cmet.2023.01.001

Products & Services: Proteins, Expression, Isolation and Analysis

Comparative analysis of allergenicity and predicted linear epitopes in α and β parvalbumin from turbot (Scophthalmus maximus)

Authors: Yuhao Huang, Zhenxing Li, Yeting Wu, Yonghong Li, Siddanakoppalu Pramod, Guanzhi Chen, Wenjia Zhu, Ziye Zhang, Hao Wang, Hong Lin

Journal: J Sci Food Agric

PubMed ID: 36606403

Doi: 10.1002/jsfa.12432

Products & Services: Proteins, Expression, Isolation and Analysis

Spike-mediated viral membrane fusion is inhibited by a specific anti-IFITM2 monoclonal antibody

Authors: Anna Basile , Carla Zannella , Margot De Marco , Giuseppina Sanna , Gianluigi Franci , Massimiliano Galdiero , Aldo Manzin , Vincenzo De Laurenzi , Massimiliano Chetta , Alessandra Rosati , Maria Caterina Turco , Liberato Marzullo

Journal: Antiviral Res

PubMed ID: 36669656

Doi: 10.1016/j.antiviral.2023.105546

Products & Services: Monoclonal Antibody Services

Click and bioorthogonal hyaluronic acid hydrogels as an ultra-tunable platform for the investigation of cell-material interactions

Authors: Nathan Lagneau, Pierre Tournier, Boris Halgand, François Loll, Yves Maugars, Jérôme Guicheux, Catherine Le Visage, Vianney Delplace

Journal: Bioact Mater

PubMed ID: 36632500

Doi: 10.1016/j.bioactmat.2022.12.022

Products & Services: Peptide Synthesis

The establishment of multiple knockout mutants of Colletotrichum orbiculare by CRISPR-Cas9 and Cre-loxP systems

Authors: Kohji Yamada, Toya Yamamoto, Kanon Uwasa, Keishi Osakabe, Yoshitaka Takano

Journal: Fungal Genet Biol

PubMed ID: 36669556

Doi: 10.1016/j.fgb.2023.103777

Products & Services: Proteins, Expression, Isolation and Analysis

Association Between Human Immunodeficiency Virus Viremia and Compromised Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant

Authors: Shi-Hsia Hwa, Jumari Snyman, Mallory Bernstein, Yashica Ganga, Sandile Cele, Daniel Muema, Chee Wah Tan, Khadija Khan, Farina Karim, Willem Hanekom, Leslie Bernstein, Stefan H E Kaufmann, Lin-Fa Wang, Thumbi Ndung'u, Alex Sigal

Journal: J Infect Dis

PubMed ID: 35975942

Doi: 10.1093/infdis/jiac343

Products & Services: Proteins, Expression, Isolation and Analysis

The NOTCH-RIPK4-IRF6-ELOVL4 Axis Suppresses Squamous Cell Carcinoma

Authors: Yue Yan, Marc-Andre Gauthier, Ahmad Malik, Iosifina Fotiadou, Michael Ostrovski, Dzana Dervovic, Logine Ghadban, Ricky Tsai, Gerald Gish, Sampath Kumar Loganathan, Daniel Schramek

Journal: Cancers (Basel)

PubMed ID: 36765696

Doi: 10.3390/cancers15030737

Products & Services: Proteins, Expression, Isolation and Analysis

The FACT-targeted drug CBL0137 enhances the effects of rituximab to inhibit B-cell non-Hodgkin's lymphoma tumor growth by promoting apoptosis and autophagy

Authors: Yan Lv, Yuxin Du, Kening Li, Xiao Ma, Juan Wang, Tongde Du, Yuxin Ma, Yue Teng, Weiyan Tang, Rong Ma, Jianqiu Wu, Jianzhong Wu, Jifeng Feng

Journal: Cell Commun Signal

PubMed ID: 36691066

Doi: 10.1186/s12964-022-01031-x

Products & Services: Proteins, Expression, Isolation and Analysis

Functions of human olfactory mucus and age-dependent changes

Authors: Tomohiro Shirai, Dan Takase, Junkichi Yokoyama, Kuniyuki Nakanishi, Chisaki Uehara, Naoko Saito, Aya Kato-Namba, Keiichi Yoshikawa

Journal: Sci Rep

PubMed ID: 36653421

Doi: 10.1038/s41598-023-27937-1

Products & Services: Gene Synthesis

Plant production of a virus-like particle-based vaccine candidate against porcine reproductive and respiratory syndrome

Authors: Jordan T VanderBurgt, Ondre Harper, Christopher P Garnham, Susanne E Kohalmi, Rima Menassa

Journal: Front Plant Sci

PubMed ID: 36760639

Doi: 10.3389/fpls.2023.1044675

Products & Services: Proteins, Expression, Isolation and Analysis

Generation of Gαi knock-out HEK293 cells illuminates Gαi-coupling diversity of GPCRs

Authors: Yuki Ono, Kouki Kawakami, Gaku Nakamura, Satoru Ishida, Junken Aoki, Asuka Inoue

Journal: Commun Biol

PubMed ID: 36709222

Doi: 10.1038/s42003-023-04465-2

Products & Services: Gene Synthesis

Unusual crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing in antigen presentation

Authors: Lenong Li, Xubiao Peng, Mansoor Batliwala, Marlene Bouvier

Journal: Res Sq

PubMed ID: 36747752

Doi: 10.21203/rs.3.rs-2500847/v1

Products & Services: Proteins, Expression, Isolation and Analysis

Comprehensive Comparison of Seven SARS-CoV-2-Specific Surrogate Virus Neutralization and Anti-Spike IgG Antibody Assays Using a Live-Virus Neutralization Assay as a Reference

Authors: Marianne Graninger, Claudia Maria Jani, Elisabeth Reuberger, Katja Prüger, Philipp Gaspar, David Niklas Springer, Christian Borsodi, Lisa Weidner, Susanne Rabady, Elisabeth Puchhammer-Stöckl, Christof Jungbauer, Eva Höltl, Judith Helene Aberle, Karin Stiasny, Lukas Weseslindtner

Journal: Microbiol Spectr

PubMed ID: 36622205

Doi: 10.1128/spectrum.02314-22

Products & Services: Proteins, Expression, Isolation and Analysis

Oncogenic KRAS signaling drives evasion of innate immune surveillance in lung adenocarcinoma by activating CD47

Authors: Huanhuan Hu, Rongjie Cheng, Yanbo Wang, Xiaojun Wang, Jianzhuang Wu, Yan Kong, Shoubin Zhan, Zhen Zhou, Hongyu Zhu, Ranran Yu, Gaoli Liang, Qingyan Wang, Xiaoju Zhu, Chen-Yu Zhang, Rong Yin, Chao Yan , Xi Chen

Journal: The Journal of Clinical Investigation

PubMed ID: 36413402

Doi: 10.1172/JCI153470

Products & Services: Mutant Libraries

Identification of B-Cell Epitopes on Capsid Protein Reveals Two Potential Neutralization Mechanisms in Red-Spotted Grouper Nervous Necrosis Virus

Authors: Zhiqi Zhang, Jing Xing, Xiaoqian Tang, Xiuzhen Sheng, Heng Chi, Wenbin Zhan

Journal: J Virol

PubMed ID: 36633407

Doi: 10.1128/jvi.01748-22

Products & Services: Peptide Synthesis

Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy

Authors: Justin M Quiles, Rita H Najor, Eileen Gonzalez, Monica Jeung, Wenjing Liang, Sarah M Burbach, Erika A Zumaya, Rachel Y Diao, Mark A Lampert, Åsa B Gustafsson

Journal: Sci Signal

PubMed ID: 36719945

Doi: 10.1126/scisignal.abo4457

Products & Services: Proteins, Expression, Isolation and Analysis

Functional characterization of a novel aminoglycoside phosphotransferase, APH(9)-Ic, and its variant from

Authors: Weina Shi, Junwan Lu, Chunlin Feng, Mengdi Gao, Anqi Li, Shuang Liu, Lei Zhang, Xueya Zhang, Qiaoling Li, Hailong Lin, Xi Lin, Kewei Li, Hailin Zhang, Yunliang Hu, Guangli Wang, Qiyu Bao, Weiyan Jiang

Journal: Front Cell Infect Microbiol

PubMed ID: 36699730

Doi: 10.3389/fcimb.2022.1097561

Products & Services: Proteins, Expression, Isolation and Analysis

Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth

Authors: Hyukjun Choi, Mirae Yeo, Yujin Kang, Hyo Jeong Kim, Seong Guk Park, Eunjung Jang, Sung Ho Park, Eunhee Kim, Sebyung Kang

Journal: J Nanobiotechnology

PubMed ID: 36597089

Doi: 10.1186/s12951-022-01762-6

Products & Services: Proteins, Expression, Isolation and Analysis

A linear DNA encoding the SARS-CoV-2 receptor binding domain elicits potent immune response and neutralizing antibodies in domestic cats

Authors: Antonella Conforti, Elisa Sanchez, Erika Salvatori, Lucia Lione, Mirco Compagnone, Eleonora Pinto, Fabio Palombo, Emanuela D'Acunto, Alessia Muzi, Giuseppe Roscilli, Yuhua Sun, Brian Viscount, James Hayward, Clay Shorrock, Diego G Diel, Joseph A Impellizeri, Luigi Aurisicchio

Journal: Mol Ther Methods Clin Dev

PubMed ID: 36618106

Doi: 10.1016/j.omtm.2022.12.015

Products & Services: Molecular Biology Reagents

AKT1 regulates UHRF1 protein stability and promotes the resistance to abiraterone in prostate cancer

Authors: Yongming Fu, Tuoyu Cao, Xiaorui Zou, Yubing Ye, Youhong Liu, Yuchong Peng, Tanggang Deng, Linglong Yin, Xiong Li

Journal: Oncogenesis

PubMed ID: 36593255

Doi: 10.1038/s41389-022-00446-y

Products & Services: Molecular Biology Reagents

The NLRP6 protein is very faintly expressed in several normal and cancerous epithelial cells and may be confused with an unrelated protein

Authors: Abdallah Mound, Gautier Goormachtigh, Fabrice Bray, Stéphanie Flament, Christian Rolando, Richard Ruez, Nathalie Martin, Amélie Decourcelle, Vanessa Dehennaut, Jean-Michel Saliou, Mathias Chamaillard, Corinne Abbadie

Journal: PLoS ONE

PubMed ID: 36662875

Doi: 10.1371/journal.pone.0279028

Products & Services: Plasmid DNA Preparation

Genomewide Association Study Identifies Copy Number Variants Associated With Warfarin Dose Response and Risk of Venous Thromboembolism in African Americans

Authors: Honghong Zhang, Cristina Alarcon, Larisa H Cavallari, Edith Nutescu, Gemma L Carvill, Minoli A Perera, Wenndy Hernandez

Journal: Clin Pharmacol Ther

PubMed ID: 36507737

Doi: 10.1002/cpt.2820

Products & Services: Molecular Biology Reagents

Cytochalasin B-Induced Membrane Vesicles from TRAIL-Overexpressing Mesenchymal Stem Cells Induce Extrinsic Pathway of Apoptosis in Breast Cancer Mouse Model

Authors: Daria S Chulpanova , Tamara V Pukhalskaia , Zarema E Gilazieva , Yuliya V Filina 1, Milana N Mansurova 1, Albert A Rizvanov 1, Valeriya V Solovyeva

Journal: Curr Issues Mol Biol .

PubMed ID: 36661524

Doi: 10.3390/cimb45010038

Products & Services: Catalog Antibody Molecular Biology Tools

α-Synuclein as a Target for Metallo-Anti-Neurodegenerative Agents

Authors: Kaiming Cao , Yang Zhu , Zhuanghao Hou , Manman Liu , Yanyan Yang , Hongze Hu , Yi Dai , Yu Wang , Siming Yuan , Guangming Huang , Jiaming Mei , Peter J Sadler , Yangzhong Liu

Journal: Angew Chem Int Ed Engl .

PubMed ID: 36345707

Doi: 10.1002/anie.202215360

Products & Services: Peptide Synthesis

Investigating the Sequence Specific Adsorption Behavior of Polypeptides at the Solid/Liquid Interface

Authors: Christopher S O'Bryan, Timothy J Murdoch, Daniel J Strickland, Katie A Rose, Denis Bendejacq, Daeyeon Lee, Russell J Composto

Journal: Langmuir

PubMed ID: 36637895

Doi: 10.1021/acs.langmuir.2c02292

Products & Services: Peptide Synthesis

Vimentin epigenetic deregulation in Bladder Cancer associates with acquisition of invasive and metastatic phenotype through epithelial-to-mesenchymal transition

Authors: Sara Monteiro-Reis, Vera Miranda-Gonçalves, Catarina Guimarães-Teixeira, Cláudia Martins-Lima, João Lobo, Diana Montezuma, Paula C Dias, Helene Neyret-Kahn, Isabelle Bernard-Pierrot, Rui Henrique, Carmen Jerónimo

Journal: Int J Biol Sci

PubMed ID: 36594099

Doi: 10.7150/ijbs.77181

Products & Services: Proteins, Expression, Isolation and Analysis

SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression

Authors: Laura Cioetto-Mazzabò, Francesca Boldrin, Claire Beauvineau, Martin Speth, Alberto Marina, Amine Namouchi, Greta Segafreddo, Mena Cimino, Sandrine Favre-Rochex, Seetha Balasingham, Beatriz Trastoy, Hélène Munier-Lehmann, Gareth Griffiths, Brigitte Gicquel, Marcelo E Guerin, Riccardo Manganelli, Noelia Alonso-Rodríguez

Journal: Nucleic Acids Res

PubMed ID: 36546765

Doi: 10.1093/nar/gkac1173

Products & Services: Proteins, Expression, Isolation and Analysis

B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV

Authors: Jacopo Polvere, Massimiliano Fabbiani, Gabiria Pastore, Ilaria Rancan, Barbara Rossetti, Miriam Durante, Sara Zirpoli, Enrico Morelli, Elena Pettini, Simone Lucchesi, Fabio Fiorino, Mario Tumbarello, Annalisa Ciabattini, Francesca Montagnani, Donata Medaglini

Journal: Commun Med (Lond)

PubMed ID: 36717688

Doi: 10.1038/s43856-023-00245-5

Products & Services: Molecular Biology Reagents

Identification of a Novel Interaction between Prohibitin (PHB-1) and Bovine RuvB-Like AAA ATPase 1

Authors: Prasanna Babu Araveti, Prajna Parimita Kar, Akshay Kuriakose, Achintya Sanju, Kota Arun Kumar, Anand Srivastava

Journal: Microbiol Spectr

PubMed ID: 36651733

Doi: 10.1128/spectrum.02502-22

Products & Services: Molecular Biology Reagents

Cellular and humoral immunity to Ebola Zaire glycoprotein and viral vector proteins following immunization with recombinant vesicular stomatitis virus-based Ebola vaccine (rVSVΔG-ZEBOV-GP)

Authors: Vanessa Raabe, Lilin Lai, Juliet Morales, Yongxian Xu, Nadine Rouphael, Richard T Davey, Mark J Mulligan

Journal: Vaccine

PubMed ID: 36725433

Doi: 10.1016/j.vaccine.2023.01.059

Products & Services: Peptide Synthesis

Design of a chimeric ACE-2/Fc-silent fusion protein with ultrahigh affinity and neutralizing capacity for SARS-CoV-2 variants

Authors: Neil M Bodie, Rina Hashimoto, David Connolly, Jennifer Chu, Kazuo Takayama, Bruce D Uhal

Journal: Antib Ther

PubMed ID: 36741194

Doi: 10.1093/abt/tbad001

Products & Services: Proteins, Expression, Isolation and Analysis

Cry51Aa Proteins Are Active against and Show a Mechanism Similar to Pore Formation Model

Authors: Ei Thinzar Soe, Zaw Lin Naing, Caihong Zhang, Lin Lin Niu, Jinrong Tang, Siqi Yu, Zhongwei Ding, Gemei Liang

Journal: J Agric Food Chem

PubMed ID: 36710440

Doi: 10.1021/acs.jafc.2c07244

Products & Services: Proteins, Expression, Isolation and Analysis

Simultaneous enzyme production, Levan-type FOS synthesis and sugar by-products elimination using a recombinant Pichia pastoris strain expressing a levansucrase-endolevanase fusion enzyme

Authors: Ángela Ávila-Fernández, Silvia Montiel, María Elena Rodríguez-Alegría, Luis Caspeta, Agustín López Munguía

Journal: Microb Cell Fact

PubMed ID: 36703199

Doi: 10.1186/s12934-022-02009-7

Products & Services: Molecular Biology Reagents

Structure of monkeypox virus DNA polymerase holoenzyme

Authors: Qi Peng, Yufeng Xie, Lu Kuai, Han Wang, Jianxun Qi, George F Gao, Yi Shi

Journal: Science (New York, N. Y.)

PubMed ID: 36520947

Doi: 10.1126/science.ade6360

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Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis

Authors: Alhaji H. Janneh, Mohamed Faisal Kassir, F. Cansu Atilgan, Stephen Tomlinson, Shikhar Mehrotra, Besim Ogretmen

Journal: Cell Reports

Doi: doi.org/10.1016/j.celrep.2022.111742

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Structure-activity relationship studies for inhibitors for vancomycin-resistant and human carbonic anhydrases

Authors: Weiwei An, Katrina J Holly, Alessio Nocentini, Ryan D Imhoff, Chad S Hewitt, Nader S Abutaleb, Xufeng Cao, Mohamed N Seleem, Claudiu T Supuran, Daniel P Flaherty

Journal: J Enzyme Inhib Med Chem

PubMed ID: 35758212

Doi: 10.1080/14756366.2022.2092729

Products & Services: Plasmid DNA Preparation

Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A

Authors: Dell'Orco D, Dal Cortivo G.

Journal: Sci Rep

PubMed ID: 31882816

Doi: 10.1038/s41598-019-56606-5

Products & Services: Gene Synthesis

SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugate

Authors: Alexander J Garvin , Alexander J Lanz , Joanna R Morris

Journal: Sci Rep

PubMed ID: 36494414

Doi: 10.1038/s41598-022-25665-6

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Prevalence of Anti-PF4 Antibodies After First and Second ChAdOx1 nCoV-19 Vaccinations in Women With Adverse Events: A Brief Report and Literature Review

Authors: Kye Won Choe, Yong Kwan Lim, Oh Joo Kweon, Mi-Kyung Lee, Jin-Won Chung, Hye Ryoun Kim

Journal: Ann Lab Med

PubMed ID: 36544343

Doi: 10.3343/alm.2023.43.3.299

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of selective hepatitis delta virus ribozyme inhibitors by high-throughput screening of small molecule libraries

Authors: Eirini D Tseligka, Stéphanie Conzelmann, Yves Cambet, Tifany Schaer, Francesco Negro, Sophie Clément

Journal: JHEP Rep

PubMed ID: 36704052

Doi: 10.1016/j.jhepr.2022.100652

Products & Services: Proteins, Expression, Isolation and Analysis

Influence of affinity tags and tobacco PR1a signal peptide on detection, purification and bioactivity analyses of the small oomycete apoplastic effectors

Authors: Jing-Hao Jin, Xue Zhou, Wang Liu, Zi-Hui Zhang, Shen-Xin Huang, Wen-Jing Zhao, Xiao-Ren Chen

Journal: Biotechnol Lett

PubMed ID: 36450976

Doi: 10.1007/s10529-022-03324-0

Products & Services: Molecular Biology Reagents

Development of a cockroach (Blattella germanica) qPCR for the objective measurement of exposure at home

Authors: Steffi Rocchi, Benoit Valot, Audrey Laboissière, Audrey Guitton, Emeline Scherer, Laurence Millon, Gabriel Reboux

Journal: Sci Total Environ

PubMed ID: 36526200

Doi: 10.1016/j.scitotenv.2022.160965

Products & Services: Molecular Biology Reagents

BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network

Authors: Xueqin Sun, Olaf Klingbeil, Bin Lu, Caizhi Wu, Carlos Ballon, Meng Ouyang, Xiaoli S Wu, Ying Jin, Yon Hwangbo, Yu-Han Huang, Tim D D Somerville, Kenneth Chang, Jung Park, Taemoon Chung, Scott K Lyons, Junwei Shi, Hannes Vogel, Michael Schulder, Christopher R Vakoc, Alea A Mills

Journal: Nature

PubMed ID: 36544023

Doi: 10.1038/s41586-022-05551-x

Products & Services: Plasmid DNA Preparation

Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA

Authors: Seow Neng Chan, Jun Wei Pek

Journal: EMBO Rep

PubMed ID: 36533631

Doi: 10.15252/embr.202154350

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