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Identification of B-Cell Epitopes on Capsid Protein Reveals Two Potential Neutralization Mechanisms in Red-Spotted Grouper Nervous Necrosis Virus
Authors: Zhiqi Zhang, Jing Xing, Xiaoqian Tang, Xiuzhen Sheng, Heng Chi, Wenbin Zhan
Journal: J Virol
PubMed ID: 36633407
Doi: 10.1128/jvi.01748-22
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Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy
Authors: Justin M Quiles, Rita H Najor, Eileen Gonzalez, Monica Jeung, Wenjing Liang, Sarah M Burbach, Erika A Zumaya, Rachel Y Diao, Mark A Lampert, Åsa B Gustafsson
Journal: Sci Signal
PubMed ID: 36719945
Doi: 10.1126/scisignal.abo4457
Functional characterization of a novel aminoglycoside phosphotransferase, APH(9)-Ic, and its variant from
Authors: Weina Shi, Junwan Lu, Chunlin Feng, Mengdi Gao, Anqi Li, Shuang Liu, Lei Zhang, Xueya Zhang, Qiaoling Li, Hailong Lin, Xi Lin, Kewei Li, Hailin Zhang, Yunliang Hu, Guangli Wang, Qiyu Bao, Weiyan Jiang
Journal: Front Cell Infect Microbiol
PubMed ID: 36699730
Doi: 10.3389/fcimb.2022.1097561
Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth
Authors: Hyukjun Choi, Mirae Yeo, Yujin Kang, Hyo Jeong Kim, Seong Guk Park, Eunjung Jang, Sung Ho Park, Eunhee Kim, Sebyung Kang
Journal: J Nanobiotechnology
PubMed ID: 36597089
Doi: 10.1186/s12951-022-01762-6
A linear DNA encoding the SARS-CoV-2 receptor binding domain elicits potent immune response and neutralizing antibodies in domestic cats
Authors: Antonella Conforti, Elisa Sanchez, Erika Salvatori, Lucia Lione, Mirco Compagnone, Eleonora Pinto, Fabio Palombo, Emanuela D'Acunto, Alessia Muzi, Giuseppe Roscilli, Yuhua Sun, Brian Viscount, James Hayward, Clay Shorrock, Diego G Diel, Joseph A Impellizeri, Luigi Aurisicchio
Journal: Mol Ther Methods Clin Dev
PubMed ID: 36618106
Doi: 10.1016/j.omtm.2022.12.015
Products & Services: Molecular Biology Reagents   
AKT1 regulates UHRF1 protein stability and promotes the resistance to abiraterone in prostate cancer
Authors: Yongming Fu, Tuoyu Cao, Xiaorui Zou, Yubing Ye, Youhong Liu, Yuchong Peng, Tanggang Deng, Linglong Yin, Xiong Li
Journal: Oncogenesis
PubMed ID: 36593255
Doi: 10.1038/s41389-022-00446-y
Products & Services: Molecular Biology Reagents   
The NLRP6 protein is very faintly expressed in several normal and cancerous epithelial cells and may be confused with an unrelated protein
Authors: Abdallah Mound, Gautier Goormachtigh, Fabrice Bray, Stéphanie Flament, Christian Rolando, Richard Ruez, Nathalie Martin, Amélie Decourcelle, Vanessa Dehennaut, Jean-Michel Saliou, Mathias Chamaillard, Corinne Abbadie
Journal: PLoS ONE
PubMed ID: 36662875
Doi: 10.1371/journal.pone.0279028
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Genomewide Association Study Identifies Copy Number Variants Associated With Warfarin Dose Response and Risk of Venous Thromboembolism in African Americans
Authors: Honghong Zhang, Cristina Alarcon, Larisa H Cavallari, Edith Nutescu, Gemma L Carvill, Minoli A Perera, Wenndy Hernandez
Journal: Clin Pharmacol Ther
PubMed ID: 36507737
Doi: 10.1002/cpt.2820
Products & Services: Molecular Biology Reagents   
Cytochalasin B-Induced Membrane Vesicles from TRAIL-Overexpressing Mesenchymal Stem Cells Induce Extrinsic Pathway of Apoptosis in Breast Cancer Mouse Model
Authors: Daria S Chulpanova , Tamara V Pukhalskaia , Zarema E Gilazieva , Yuliya V Filina 1, Milana N Mansurova 1, Albert A Rizvanov 1, Valeriya V Solovyeva
Journal: Curr Issues Mol Biol .
PubMed ID: 36661524
Doi: 10.3390/cimb45010038
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α-Synuclein as a Target for Metallo-Anti-Neurodegenerative Agents
Authors: Kaiming Cao , Yang Zhu , Zhuanghao Hou , Manman Liu , Yanyan Yang , Hongze Hu , Yi Dai , Yu Wang , Siming Yuan , Guangming Huang , Jiaming Mei , Peter J Sadler , Yangzhong Liu
Journal: Angew Chem Int Ed Engl .
PubMed ID: 36345707
Doi: 10.1002/anie.202215360
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Investigating the Sequence Specific Adsorption Behavior of Polypeptides at the Solid/Liquid Interface
Authors: Christopher S O'Bryan, Timothy J Murdoch, Daniel J Strickland, Katie A Rose, Denis Bendejacq, Daeyeon Lee, Russell J Composto
Journal: Langmuir
PubMed ID: 36637895
Doi: 10.1021/acs.langmuir.2c02292
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Vimentin epigenetic deregulation in Bladder Cancer associates with acquisition of invasive and metastatic phenotype through epithelial-to-mesenchymal transition
Authors: Sara Monteiro-Reis, Vera Miranda-Gonçalves, Catarina Guimarães-Teixeira, Cláudia Martins-Lima, João Lobo, Diana Montezuma, Paula C Dias, Helene Neyret-Kahn, Isabelle Bernard-Pierrot, Rui Henrique, Carmen Jerónimo
Journal: Int J Biol Sci
PubMed ID: 36594099
Doi: 10.7150/ijbs.77181
SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression
Authors: Laura Cioetto-Mazzabò, Francesca Boldrin, Claire Beauvineau, Martin Speth, Alberto Marina, Amine Namouchi, Greta Segafreddo, Mena Cimino, Sandrine Favre-Rochex, Seetha Balasingham, Beatriz Trastoy, Hélène Munier-Lehmann, Gareth Griffiths, Brigitte Gicquel, Marcelo E Guerin, Riccardo Manganelli, Noelia Alonso-Rodríguez
Journal: Nucleic Acids Res
PubMed ID: 36546765
Doi: 10.1093/nar/gkac1173
B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV
Authors: Jacopo Polvere, Massimiliano Fabbiani, Gabiria Pastore, Ilaria Rancan, Barbara Rossetti, Miriam Durante, Sara Zirpoli, Enrico Morelli, Elena Pettini, Simone Lucchesi, Fabio Fiorino, Mario Tumbarello, Annalisa Ciabattini, Francesca Montagnani, Donata Medaglini
Journal: Commun Med (Lond)
PubMed ID: 36717688
Doi: 10.1038/s43856-023-00245-5
Products & Services: Molecular Biology Reagents   
Identification of a Novel Interaction between Prohibitin (PHB-1) and Bovine RuvB-Like AAA ATPase 1
Authors: Prasanna Babu Araveti, Prajna Parimita Kar, Akshay Kuriakose, Achintya Sanju, Kota Arun Kumar, Anand Srivastava
Journal: Microbiol Spectr
PubMed ID: 36651733
Doi: 10.1128/spectrum.02502-22
Products & Services: Molecular Biology Reagents   
Cellular and humoral immunity to Ebola Zaire glycoprotein and viral vector proteins following immunization with recombinant vesicular stomatitis virus-based Ebola vaccine (rVSVΔG-ZEBOV-GP)
Authors: Vanessa Raabe, Lilin Lai, Juliet Morales, Yongxian Xu, Nadine Rouphael, Richard T Davey, Mark J Mulligan
Journal: Vaccine
PubMed ID: 36725433
Doi: 10.1016/j.vaccine.2023.01.059
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Design of a chimeric ACE-2/Fc-silent fusion protein with ultrahigh affinity and neutralizing capacity for SARS-CoV-2 variants
Authors: Neil M Bodie, Rina Hashimoto, David Connolly, Jennifer Chu, Kazuo Takayama, Bruce D Uhal
Journal: Antib Ther
PubMed ID: 36741194
Doi: 10.1093/abt/tbad001
Cry51Aa Proteins Are Active against and Show a Mechanism Similar to Pore Formation Model
Authors: Ei Thinzar Soe, Zaw Lin Naing, Caihong Zhang, Lin Lin Niu, Jinrong Tang, Siqi Yu, Zhongwei Ding, Gemei Liang
Journal: J Agric Food Chem
PubMed ID: 36710440
Doi: 10.1021/acs.jafc.2c07244
Simultaneous enzyme production, Levan-type FOS synthesis and sugar by-products elimination using a recombinant Pichia pastoris strain expressing a levansucrase-endolevanase fusion enzyme
Authors: Ángela Ávila-Fernández, Silvia Montiel, María Elena Rodríguez-Alegría, Luis Caspeta, Agustín López Munguía
Journal: Microb Cell Fact
PubMed ID: 36703199
Doi: 10.1186/s12934-022-02009-7
Products & Services: Molecular Biology Reagents   
Structure of monkeypox virus DNA polymerase holoenzyme
Authors: Qi Peng, Yufeng Xie, Lu Kuai, Han Wang, Jianxun Qi, George F Gao, Yi Shi
Journal: Science (New York, N. Y.)
PubMed ID: 36520947
Doi: 10.1126/science.ade6360
Products & Services: Gene Synthesis   
Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
Authors: Alhaji H. Janneh, Mohamed Faisal Kassir, F. Cansu Atilgan, Stephen Tomlinson, Shikhar Mehrotra, Besim Ogretmen
Journal: Cell Reports
Doi: doi.org/10.1016/j.celrep.2022.111742
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Structure-activity relationship studies for inhibitors for vancomycin-resistant and human carbonic anhydrases
Authors: Weiwei An, Katrina J Holly, Alessio Nocentini, Ryan D Imhoff, Chad S Hewitt, Nader S Abutaleb, Xufeng Cao, Mohamed N Seleem, Claudiu T Supuran, Daniel P Flaherty
Journal: J Enzyme Inhib Med Chem
PubMed ID: 35758212
Doi: 10.1080/14756366.2022.2092729
Products & Services: Plasmid DNA Preparation   
Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A
Authors: Dell'Orco D, Dal Cortivo G.
Journal: Sci Rep
PubMed ID: 31882816
Doi: 10.1038/s41598-019-56606-5
Products & Services: Gene Synthesis   
SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugate
Authors: Alexander J Garvin , Alexander J Lanz , Joanna R Morris
Journal: Sci Rep
PubMed ID: 36494414
Doi: 10.1038/s41598-022-25665-6
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Prevalence of Anti-PF4 Antibodies After First and Second ChAdOx1 nCoV-19 Vaccinations in Women With Adverse Events: A Brief Report and Literature Review
Authors: Kye Won Choe, Yong Kwan Lim, Oh Joo Kweon, Mi-Kyung Lee, Jin-Won Chung, Hye Ryoun Kim
Journal: Ann Lab Med
PubMed ID: 36544343
Doi: 10.3343/alm.2023.43.3.299
Identification of selective hepatitis delta virus ribozyme inhibitors by high-throughput screening of small molecule libraries
Authors: Eirini D Tseligka, Stéphanie Conzelmann, Yves Cambet, Tifany Schaer, Francesco Negro, Sophie Clément
Journal: JHEP Rep
PubMed ID: 36704052
Doi: 10.1016/j.jhepr.2022.100652
Influence of affinity tags and tobacco PR1a signal peptide on detection, purification and bioactivity analyses of the small oomycete apoplastic effectors
Authors: Jing-Hao Jin, Xue Zhou, Wang Liu, Zi-Hui Zhang, Shen-Xin Huang, Wen-Jing Zhao, Xiao-Ren Chen
Journal: Biotechnol Lett
PubMed ID: 36450976
Doi: 10.1007/s10529-022-03324-0
Products & Services: Molecular Biology Reagents   
Development of a cockroach (Blattella germanica) qPCR for the objective measurement of exposure at home
Authors: Steffi Rocchi, Benoit Valot, Audrey Laboissière, Audrey Guitton, Emeline Scherer, Laurence Millon, Gabriel Reboux
Journal: Sci Total Environ
PubMed ID: 36526200
Doi: 10.1016/j.scitotenv.2022.160965
Products & Services: Molecular Biology Reagents   
BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network
Authors: Xueqin Sun, Olaf Klingbeil, Bin Lu, Caizhi Wu, Carlos Ballon, Meng Ouyang, Xiaoli S Wu, Ying Jin, Yon Hwangbo, Yu-Han Huang, Tim D D Somerville, Kenneth Chang, Jung Park, Taemoon Chung, Scott K Lyons, Junwei Shi, Hannes Vogel, Michael Schulder, Christopher R Vakoc, Alea A Mills
Journal: Nature
PubMed ID: 36544023
Doi: 10.1038/s41586-022-05551-x
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Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA
Authors: Seow Neng Chan, Jun Wei Pek
Journal: EMBO Rep
PubMed ID: 36533631
Doi: 10.15252/embr.202154350
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The effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple
Authors: Runmin Che, Changhai Liu, Qi Wang, Wenyan Tu, Ping Wang, Chao Li, Xiaoqing Gong, Ke Mao, Hao Feng, Lili Huang, Pengmin Li, Fengwang Ma
Journal: Autophagy
PubMed ID: 36449354
Doi: 10.1080/15548627.2022.2153573
Tissue replication and mucosal swab detection of Sosuga virus in Syrian hamsters in the absence of overt tissue pathology and clinical disease
Authors: Stephen R Welch, Jana M Ritter, Amy J Schuh, Sarah C Genzer, Teresa E Sorvillo, Jessica R Harmon, JoAnn D Coleman-McCray, Shilpi Jain, Punya Shrivastava-Ranjan, Josilene Nascimento Seixas, Lindsey B Estetter, Pamela S Fair, Jonathan S Towner, Joel M Montgomery, César G Albariño, Christina F Spiropoulou, Jessica R Spengler
Journal: Antiviral Res
PubMed ID: 36521633
Doi: 10.1016/j.antiviral.2022.105490
Roles of the transcriptional regulators Fts1, YlNrg1, YlTup1, and YlSsn6 in the repression of the yeast-to-filament transition in the dimorphic yeast Yarrowia lipolytica
Authors: Yi-Sheng Mao, Jia-Wen Chen, Zhen-Hua Wang, Meng-Yang Xu, Xiang-Dong Gao
Journal: Mol Microbiol
PubMed ID: 36537557
Doi: 10.1111/mmi.15017
Products & Services: Molecular Biology Reagents   
Functional recovery of myocardial infarction by specific EBP-PR1P peptides bridging injectable cardiac extracellular matrix and vascular endothelial growth factor
Authors: Wenxuan Cao, Hong Zhang, Ning Zhou, Runxue Zhou, Xiaojing Zhang, Jia Yin, Jin Deng, Xiang Ao, Chunying Shi
Journal: J Biomed Mater Res A
PubMed ID: 36579729
Doi: 10.1002/jbm.a.37483
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Cadmium chloride exposure impairs the growth and behavior of Drosophila via ferroptosis
Authors: Yingxia Hu, Haijie Wu, Chenying Lu, Hanqing Xu, Boyang Li, Wanchun Guan, Mingjiang Wu, Yitian Gao, Haibin Tong
Journal: Sci Total Environ
PubMed ID: 36581278
Doi: 10.1016/j.scitotenv.2022.161183
Products & Services: Molecular Biology Reagents   
Polymyxin B neutralizes endotoxin and improves the quality of chicken semen during liquid storage
Authors: Ei Ei Win Maung, Pangda Sopha Sushadi, Atsushi Asano
Journal: Theriogenology
PubMed ID: 36577162
Doi: 10.1016/j.theriogenology.2022.12.027
Products & Services: Molecular Biology Reagents   
Electrical stimulation of piezoelectric BaTiO3 coated Ti6Al4V scaffolds promote antiinflammatory polarization of macrophage and bone repair via MAPK/JNK inhibition and OXPHOS activation
Authors: Hao Wu, Dong Hui, Zhen Tang, Yu Chen, Yichao Liu, Mo Wang, Xinghui Wei, Ning Wang, Shusen Bao, Dongmei Yu, Zhigang Wu, Zhenda Yang, Xiaokang Li, Zheng Guo, Lei Shi
Journal: Biomaterials
Doi: 10.1016/j.biomaterials.2022.121990
mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum
Authors: Clifford T H Hayashi , Yi Cao , Leor C Clark , Abhai K Tripathi , Fidel Zavala , Garima Dwivedi , James Knox , Mohamad-Gabriel Alameh , Paulo J C Lin , Ying K Tam , Drew Weissman , Nirbhay Kumar
Journal: NPJ Vaccines
PubMed ID: 36456563
Doi: 10.1038/s41541-022-00577-8
Products & Services: Codon Optimization   
DNA-protein cross-links between abasic DNA damage and mitochondrial transcription factor A (TFAM)
Authors: Wenyan Xu , Jin Tang , Linlin Zhao
Journal: Nucleic Acids Res
PubMed ID: 36583367
Doi: 10.1093/nar/gkac1214
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Principles of mitoribosomal small subunit assembly in eukaryotes
Authors: Nathan J Harper, Chloe Burnside, Sebastian Klinge
Journal: Nature
PubMed ID: 36482135
Doi: 10.1038/s41586-022-05621-0
Products & Services: Gene Synthesis   
An epitope-directed selection strategy facilitating the identification of Frizzled receptor selective antibodies
Authors: Qiangqiang Ge, Maikun Teng, Xu Li, Qiong Guo, Yuyong Tao
Journal: Structure
PubMed ID: 36513066
Doi: 10.1016/j.str.2022.11.009
Long-Term Adaptation to Galactose as a Sole Carbon Source Selects for Mutations Outside the Canonical GAL Pathway
Authors: Artemiza A Martínez, Andrew Conboy, Sean W Buskirk, Daniel A Marad, Gregory I Lang
Journal: J Mol Evol
PubMed ID: 36482210
Doi: 10.1007/s00239-022-10079-9
LINC00324 promotes cell proliferation and metastasis of esophageal squamous cell carcinoma through sponging miR-493-5p via MAPK signaling pathway
Authors: Uttam Sharma, Manjit Kaur Rana, Karuna Singh, Aklank Jain
Journal: Biochem Pharmacol
PubMed ID: 36493845
Doi: 10.1016/j.bcp.2022.115372
Products & Services: Molecular Biology Reagents   
Antibody Response of Heterologous vs Homologous Messenger RNA Vaccine Boosters Against the Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant: Interim Results from the PRIBIVAC Study, a Randomized Clinical Trial
Authors: Xuan Ying Poh, Chee Wah Tan, I Russel Lee, Jean-Marc Chavatte, Siew-Wai Fong, Tessa Prince, Catherine Hartley, Aileen Y Y Yeoh, Suma Rao, Po Ying Chia, Sean W X Ong, Tau Hong Lee, Sapna P Sadarangani, Ray J H Lin, Clarissa Lim, Jefanie Teo, Daniel R X Lim, Wanni Chia, Julian A Hiscox, Lisa F P Ng, Ee Chee Ren, Raymond T P Lin, Laurent Renia, David Chien Lye, Lin-Fa Wang, Barnaby E Young
Journal: Clin Infect Dis
PubMed ID: 35543372
Doi: 10.1093/cid/ciac345
Products & Services: Recombinant Proteins   
Early TNF-Dependent Regulation of Excitatory and Inhibitory Synapses on Striatal Direct Pathway Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease
Authors: Julien Chambon, Pragya Komal, Gil M Lewitus, Gina M Kemp, Simone Valade, Houaria Adaïdi, Noura Al Bistami, David Stellwagen
Journal: J Neurosci
PubMed ID: 36517241
Doi: 10.1523/JNEUROSCI.1655-22.2022
Products & Services: Molecular Biology Reagents   
A BioBricks Metabolic Engineering Platform for the Biosynthesis of Anthracyclinones in Streptomyces coelicolor
Authors: Rongbin Wang , Jennifer Nguyen , Jacob Hecht , Nora Schwartz , Katelyn V Brown , Larissa V Ponomareva, Magdalena Niemczura , Dino van Dissel , Gilles P van Wezel , Jon S Thorson, Mikko Metsä-Ketelä , Khaled A Shaaban, S Eric Nybo
Journal: ACS Synth Biol
PubMed ID: 36378506
Doi: 10.1021/acssynbio.2c00498
Products & Services: Gene Synthesis   
Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling
Authors: Bärbel Schröfelbauer, Patrick K Kimes, Paige Hauke, Charlotte E Reid, Kevin Shao, Sarah J Hill, Rafael Irizarry, William C Hahn
Journal: Proc Natl Acad Sci U S A
PubMed ID: 36574667
Doi: 10.1073/pnas.2206751120
Disease modification and symptom relief in osteoarthritis using a mutated GCP-2/CXCL6 chemokine
Authors: Sara Caxaria, Nikolaos Kouvatsos, Suzanne E Eldridge, Mario Alvarez-Fallas, Anne-Sophie Thorup, Daniela Cici, Aida Barawi, Ammaarah Arshed, Danielle Strachan, Giulia Carletti, Xinying Huang, Sabah Bharde, Melody Deniz, Jacob Wilson, Bethan L Thomas, Costantino Pitzalis, Francesco Paolo Cantatore, Manasi Sayilekshmy, Shafaq Sikandar, Frank P Luyten, Thomas Pap, Joanna C Sherwood, Anthony J Day, Francesco Dell'Accio
Journal: EMBO Mol Med
PubMed ID: 36507558
Doi: 10.15252/emmm.202216218
Products & Services: Molecular Biology Reagents   
Comment on: Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage
Authors: Luiza H Galarion, Justin E Clarke, Harry Schofield, Alex J O'Neill
Journal: J Antimicrob Chemother
PubMed ID: 36416794
Doi: 10.1093/jac/dkac397
Products & Services: Custom RNAi Services   
High-Throughput and Efficient Intracellular Delivery Method via a Vibration-Assisted Nanoneedle/Microfluidic Composite System
Authors: Xuan Li , Yuan Ma , Yu Xue , Xuanhe Zhang , Linwen Lv , Qianghua Quan , Yiqing Chen , Guoxu Yu , Zhenwei Liang , Xinping Zhang , Ding Weng , Lei Chen , Kui Chen , Xin Han , Jiadao Wang
Journal: ACS Nano
PubMed ID: 36479877
Doi: 10.1021/acsnano.2c07852

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