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页码: 74/1028 每页显示数量

Urease of Aspergillus fumigatus Is Required for Survival in Macrophages and Virulence

Authors: Zhenzhen Xiong, Nan Zhang, Liru Xu, Zhiduo Deng, Jarukitt Limwachiranon, Yaojie Guo, Yi Han, Wei Yang, Daniel H Scharf

Journal: Microbiol Spectr

PubMed ID: 36916906

Doi: 10.1128/spectrum.03508-22

Products & Services: Proteins, Expression, Isolation and Analysis

Plasticity in airway smooth muscle differentiation during mouse lung development

Authors: Katharine Goodwin, Bezia Lemma, Pengfei Zhang, Adam Boukind, Celeste M Nelson

Journal: Dev Cell

PubMed ID: 36868232

Doi: 10.1016/j.devcel.2023.02.002

Products & Services: Proteins, Expression, Isolation and Analysis

Novel multi-epitope vaccine against bovine brucellosis: approach from immunoinformatics to expression

Authors: Somayyeh Rahimnahal, Shahnaz Yousefizadeh, Yahya Mohammadi

Journal: J Biomol Struct Dyn

PubMed ID: 36927475

Doi: 10.1080/07391102.2023.2188962

Products & Services: Proteins, Expression, Isolation and Analysis

Vimentin Is an Attachment Receptor for Mycoplasma pneumoniae P1 Protein

Authors: Kailan Peng, Yating Liao, Xia Li, Dongdong Zeng, Youyuan Ye, Li Chen, Zhuo Zeng, Yanhua Zeng

Journal: Microbiol Spectr

PubMed ID: 36912679

Doi: 10.1128/spectrum.04489-22

Products & Services: Molecular Biology Reagents

Mapping the conformational landscape of the stimulatory heterotrimeric G protein

Authors: Shuya Kate Huang, Louis-Philippe Picard, Rima S M Rahmatullah, Aditya Pandey, Ned Van Eps, Roger K Sunahara, Oliver P Ernst, Adnan Sljoka, R Scott Prosser

Journal: Nat Struct Mol Biol

PubMed ID: 36997760

Doi: 10.1038/s41594-023-00957-1

Products & Services: Molecular Biology Reagents

Structure-activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor

Authors: Yufang Deng, Claudia V Perez Almeria, Lieke van Gijzel, Kay Schaller, Line Vedel, David E Gloriam, Trond Ulven, Hans Bräuner-Osborne

Journal: Basic Clin Pharmacol Toxicol

PubMed ID: 36930875

Doi: 10.1111/bcpt.13861

Products & Services: Molecular Biology Reagents

Human immunoglobulin gene allelic variation impacts germline-targeting vaccine priming

Authors: Allan C deCamp, Martin M Corcoran, William J Fulp, Jordan R Willis, Christopher A Cottrell, Daniel L V Bader, Oleksandr Kalyuzhniy, David J Leggat, Kristen W Cohen, Ollivier Hyrien, Sergey Menis, Greg Finak, Lamar Ballweber-Fleming, Abhinaya Srikanth, Jason R Plyler, Farhad Rahaman, Angela Lombardo, Vincent Philiponis, Rachael E Whaley, Aaron Seese, Joshua Brand, Alexis M Ruppel, Wesley Hoyland, Celia R Mahoney, Alberto Cagigi, Alison Taylor, David M Brown, David R Ambrozak, Troy Sincomb, Tina-Marie Mullen, Janine Maenza, Orpheus Kolokythas, Nadia Khati, Jeffrey Bethony, Mario Roederer, David Diemert, Richard A Koup, Dagna S Laufer, Juliana M McElrath, Adrian B McDermott, Gunilla B Karlsson Hedestam, William R Schief

Journal: medrxiv

PubMed ID: 36993183

Doi: 10.1101/2023.03.10.23287126

Products & Services: Molecular Biology Reagents

Impact of homologous and heterologous boosters in neutralizing antibodies titers against SARS-CoV-2 Omicron in solid-organ transplant recipients

Authors: Aracelly Gaete-Argel, Vicente Saavedra-Alarcón, Denis Sauré, Luis Alonso-Palomares, Mónica L Acevedo, Marion Alarcón, Susan M Bueno, Alexis M Kalergis, Ricardo Soto-Rifo, Fernando Valiente-Echeverría, Claudia P Cortes

Journal: Front Immunol

PubMed ID: 36999018

Doi: 10.3389/fimmu.2023.1135478

Products & Services: Molecular Biology Reagents

Production of neutralizing antibody fragment variants in the cytoplasm of E coli for rapid screening: SARS-CoV-2 a case study

Authors: Aatir A Tungekar, Rosario Recacha, Lloyd W Ruddock

Journal: Sci Rep

PubMed ID: 36927743

Doi: 10.1038/s41598-023-31369-2

Products & Services: Molecular Biology Reagents

Identification of specific and shared epitopes at the extreme N-terminal VP1 of Coxsackievirus A4, A2 and A5 by monoclonal antibodies

Authors: Yu-Xuan Tian, Wei-Ping Jin, Zhen-Ni Wei, Shi-Yun Lv, Meng-Jun Wang, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Shuo Shen

Journal: Virus Res

PubMed ID: 36805409

Doi: 10.1016/j.virusres.2023.199074

Products & Services: Peptide Synthesis

Active Site Aromatic Residues Play a Dual Role in the Substrate Interaction and Protein Structure in Functional Dimers of CYP121A1 of

Authors: Christopher S Campomizzi, Amit Kumar, Patil Pranita Uttamrao, Jack J Stallone, George E Ghanatios, Thenmalarchelvi Rathinavelan, D Fernando Estrada

Journal: ACS Infect Dis

PubMed ID: 36976833

Doi: 10.1021/acsinfecdis.2c00531

Products & Services: Proteins, Expression, Isolation and Analysis

PF-D-Trimer, a protective SARS-CoV-2 subunit vaccine: immunogenicity and application

Authors: Zhihao Zhang, Jinhu Zhou, Peng Ni, Bing Hu, Normand Jolicoeur, Shuang Deng, Qian Xiao, Qian He, Gai Li, Yan Xia, Mei Liu, Cong Wang, Zhizheng Fang, Nan Xia, Zhe-Rui Zhang, Bo Zhang, Kun Cai, Yan Xu, Binlei Liu

Journal: npj Vaccines

PubMed ID: 36922524

Doi: 10.1038/s41541-023-00636-8

Products & Services: Gene Synthesis

High Autophagy Patterns in Swelling Platelets During Apheresis Platelet Storage

Authors: Lu Yu, Shifang Yu, Yunlei He, Gang Deng, Qiang Li

Journal: Indian J Hematol Blood Transfus

PubMed ID: 37790743

Doi: 10.1007/s12288-023-01638-1

Products & Services: Proteins, Expression, Isolation and Analysis

Antitumor effect of neoantigen-reactive T cells combined with PD1 inhibitor therapy in mouse lung cancer

Authors: Huan Qin, Haiyan Hu, Ximing Liao, Pei Zhao, Wenjuan He, Xiaoping Su, Jiaxing Sun, Qiang Li

Journal: J Cancer Res Clin Oncol

PubMed ID: 36933035

Doi: 10.1007/s00432-023-04683-5

Products & Services: Peptide Synthesis

Fine-tuning Bacterial Cyclic di-AMP Production for Durable Antitumor Effects Through the Activation of the STING Pathway

Authors: Yu Jiang, Xiyuan Li, Fenghui Qian, Bingbing Sun, Xiyuan Wang, Yan Zhang, Deqiang Zhang, Meiyu Geng, Zuoquan Xie, Sheng Yang

Journal: Research (Wash D C)

PubMed ID: 37011280

Doi: 10.34133/research.0102

Products & Services: Gene Synthesis

The diurnal salivary glands transcriptome of Dermacentor nuttalli from the first four days of blood feeding

Authors: Hejia Ma, Yanjun Lao, Susu Liu, Jingkai Ai, Xue Sun, Wei Zhang, Ming Kang, Jixu Li, Yali Sun

Journal: Ticks Tick Borne Dis

PubMed ID: 37001418

Doi: 10.1016/j.ttbdis.2023.102178

Products & Services: PCR Cloning and Subcloning

Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

Authors: Thayne H Dickey, Rui Ma, Sachy Orr-Gonzalez, Tarik Ouahes, Palak Patel, Holly McAleese, Brandi Butler, Elizabeth Eudy, Brett Eaton, Michael Murphy, Jennifer L Kwan, Nichole D Salinas, Michael R Holbrook, Lynn E Lambert, Niraj H Tolia

Journal: Cell Rep

PubMed ID: 36943870

Doi: 10.1016/j.celrep.2023.112266

Products & Services: Recombinant Proteins

Ferulic Acid Alleviates Hepatic Lipid Accumulation and Inflammation by Improving Proximal and Distal Intestinal Barriers in NAFLD Mice

Authors: Jiaojiao Fu, Jingyan Yang, Liying He, Caixia Yang, Jing He, Yanan Hua, Jinlin Guo, Sijing Liu

Journal: Tohoku J Exp Med

PubMed ID: 36927682

Doi: 10.1620/tjem.2023.J023

Products & Services: Molecular Biology Reagents

RHINO restricts MMEJ activity to mitosis

Authors: Alessandra Brambati, Olivia Sacco, Sarina Porcella, Joshua Heyza, Mike Kareh, Jens C Schmidt, Agnel Sfeir

Journal: biorxiv

PubMed ID: 36993461

Doi: 10.1101/2023.03.16.532763

Products & Services: Recombinant Proteins

Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases

Authors: George D Lampe, Rebeca T King, Tyler S Halpin-Healy, Sanne E Klompe, Marcus I Hogan, Phuc Leo H Vo, Stephen Tang, Alejandro Chavez, Samuel H Sternberg

Journal: Nat Biotechnol

PubMed ID: 36991112

Doi: 10.1038/s41587-023-01748-1

Products & Services: Gene Synthesis

Myosin-X recruits lamellipodin to filopodia tips

Authors: Ana Popović, Mitro Miihkinen, Sujan Ghimire, Rafael Saup, Max L B Grönloh, Neil J Ball, Benjamin T Goult, Johanna Ivaska, Guillaume Jacquemet

Journal: J Cell Sci

PubMed ID: 36861887

Doi: 10.1242/jcs.260574

Products & Services: Gene Synthesis

Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders

Authors: Elżbieta Wątor , Piotr Wilk , Artur Biela, Michał Rawski , Krzysztof M Zak, Wieland Steinchen , Gert Bange, Sebastian Glatt , Przemysław Grudnik

Journal: Nature Communications

PubMed ID: 36973244

Doi: 10.1038/s41467-023-37305-2

Products & Services: Gene Synthesis Gene Synthesis

Mucus-penetrating nonviral gene vaccine processed in the epithelium for inducing advanced vaginal mucosal immune responses

Authors: Qunjie Bi, Xu Song, Yangyang Zhao, Xueyi Hu, Huan Yang, Rongrong Jin, Yu Nie

Journal: Acta Pharmacuetica Sinica.B

PubMed ID: 36970203

Doi: 10.1016/j.apsb.2022.11.004

Products & Services: Peptide Synthesis

A riboswitch separated from its ribosome-binding site still regulates translation

Authors: Griffin M Schroeder, Olayinka Akinyemi, Jeffrey Malik, Caroline M Focht, Elizabeth M Pritchett, Cameron D Baker, James P McSally, Jermaine L Jenkins, David H Mathews, Joseph E Wedekind

Journal: Nucleic Acids Research

PubMed ID: 36762498

Doi: 10.1093/nar/gkad056.

Products & Services: Gene Synthesis

A swapped genetic code prevents viral infections and gene transfer

Authors: Akos Nyerges, Svenja Vinke, Regan Flynn, Siân V Owen, Eleanor A Rand, Bogdan Budnik, Eric Keen, Kamesh Narasimhan, Jorge A Marchand, Maximilien Baas-Thomas, Min Liu, Kangming Chen, Anush Chiappino-Pepe, Fangxiang Hu, Michael Baym, George M Church

Journal: Nature

PubMed ID: 36922599

Doi: 10.1038/s41586-023-05824-z

Products & Services: Gene Synthesis

New insights underlying the early events of dopaminergic dysfunction in Parkinson’s Disease

Authors: Hannah L. Dela Cruz, Esther L. Dela Cruz, Cody J. Zurhellen, Herbert T. York, Jim A. Baun, Joshua L. Dela Cruz, Jay S. Dela Cruz

Journal: biorxiv

Doi: 10.1101/2020.09.27.313957

Products & Services: Endotoxin Detection & Removal System

The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite development within the tsetse vector

Authors: Aitor Casas-Sanchez, Raghavendran Ramaswamy, Samïrah Perally, Lee R Haines, Clair Rose, Marcela Aguilera-Flores, Susana Portillo, Margot Verbeelen, Shahid Hussain, Laura Smithson, Cristina Yunta, Michael J Lehane, Sue Vaughan, Jan van den Abbeele, Igor C Almeida, Martin J Boulanger, Álvaro Acosta-Serrano

Journal: PLoS Pathog

PubMed ID: 36996244

Doi: 10.1371/journal.ppat.1011269

Products & Services: Proteins, Expression, Isolation and Analysis

Highly Sensitive and Selective Detection of Inorganic Phosphates in the Water Environment by Biosensors Based on Bioluminescence Resonance Energy Transfer

Authors: Jie Yu, Yan Zhang, Yanping Zhao, Xuxiang Zhang, Hongqiang Ren

Journal: Anal Chem

PubMed ID: 36942460

Doi: 10.1021/acs.analchem.2c04748

Products & Services: Proteins, Expression, Isolation and Analysis

Peptides that Mimic RS repeats modulate phase separation of SRSF1, revealing a reliance on combined stacking and electrostatic interactions

Authors: Talia Fargason, Naiduwadura Ivon Upekala De Silva, Erin King, Zihan Zhang, Trenton Paul, Jamal Shariq, Steve Zaharias, Jun Zhang

Journal: Elife

PubMed ID: 36862748

Doi: 10.7554/eLife.84412

Products & Services: Molecular Biology Reagents

Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment

Authors: Christine McInnis, Shilpa Bhatia, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Ann Marie Egloff, Lakshmi Srinivasan, Daniel C Pregibon, Anthony J Coyle, Glenn J Hanna

Journal: J Immunother Cancer

PubMed ID: 36990508

Doi: 10.1136/jitc-2023-006721

Products & Services: Peptide Synthesis

Interaction of SARS-CoV-2 Nucleocapsid Protein and Human RNA Helicases DDX1 and DDX3X Modulates Their Activities on Double-Stranded RNA

Authors: Camilla Lodola, Massimiliano Secchi, Virginia Sinigiani, Antonella De Palma, Rossana Rossi, Davide Perico, Pier Luigi Mauri, Giovanni Maga

Journal: Int J Mol Sci

PubMed ID: 36982856

Doi: 10.3390/ijms24065784

Products & Services: Plasmid DNA Preparation

Genetically engineered CXCR4-modified exosomes for delivery of miR-126 mimics to macrophages alleviate periodontitis

Authors: Haotian Luo, Danying Chen, Ruoyu Li, Runze Li, Yungshan Teng, Yang Cao, Xuenong Zou, Weicai Wang, Chen Zhou

Journal: J Nanobiotechnology

PubMed ID: 36991451

Doi: 10.1186/s12951-023-01863-w

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of Three Human POLH Germline Variants Defective in Complementing the UV- and Cisplatin-Sensitivity of POLH-Deficient Cells

Authors: Mina Yeom, Jin-Kyung Hong, Joo-Ho Shin, Yunjong Lee, Frederick Peter Guengerich, Jeong-Yun Choi

Journal: Int J Mol Sci

PubMed ID: 36982269

Doi: 10.3390/ijms24065198

Products & Services: Custom DNA/RNA Oligos

The Influence of Protein Charge and Molecular Weight on the Affinity of Aptamers

Authors: Alissa Drees, Tung Lam Trinh, Markus Fischer

Journal: Pharmaceuticals (Basel)

PubMed ID: 36986556

Doi: 10.3390/ph16030457

Products & Services: Custom DNA/RNA Oligos

Dissection of Antibody Responses of Gam-COVID-Vac-Vaccinated Subjects Suggests Involvement of Epitopes Outside RBD in SARS-CoV-2 Neutralization

Authors: Maria Byazrova, Pia Gattinger, Ekaterina Astakhova, Gerhard Hofer, Musa Khaitov, Alexander Filatov, Rudolf Valenta

Journal: Int J Mol Sci

PubMed ID: 36982183

Doi: 10.3390/ijms24065104

Products & Services: Recombinant Antibody Expression

Genome-wide identification and characterization of tomato 14–3-3 (SlTFT) genes and functional analysis of SlTFT6 under heat stress

Authors: Yunfei Liang, Fang Ma, Ruili Zhang, Wenyu Li, Jiao Dang, Huai Su, Boyu Li, Tixu Hu, Mingke Zhang, Yan Liang, Xiangqiang Zhan

Journal: Physiologia plantarum

PubMed ID: 36906839

Doi: 10.1111/ppl.13888

Products & Services: Transient Expression(INACTIVE)

Development and Evaluation of Recombinant B-Cell Multi-Epitopes of PDHA1 and GAPDH as Subunit Vaccines against Infection in Flounder ()

Authors: Xiuzhen Sheng, Honghua Zhang, Min Liu, Xiaoqian Tang, Jing Xing, Heng Chi, Wenbin Zhan

Journal: Vaccines (Basel)

PubMed ID: 36992208

Doi: 10.3390/vaccines11030624

Products & Services: Peptide Synthesis

To Explore the Binding Affinity of Human γ-Secretase Activating Protein (GSAP) Isoform 4 with APP-C99 Peptides

Authors: Deekshi Angira, Sonali Chaudhary, Arumugam Abiramasundari, Vijay Thiruvenkatam

Journal: ACS Omega

PubMed ID: 37065030

Doi: 10.1021/acsomega.3c01117

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of Filamin A Mechanobinding Partner III: SAV1 Specifically Interacts with Filamin A Mechanosensitive Domain 21

Authors: Huaguan Zhang, Zhenfeng Mao, Ziwei Yang, Fumihiko Nakamura

Journal: Biochemistry

PubMed ID: 36857526

Doi: 10.1021/acs.biochem.2c00665

Products & Services: Molecular Biology Reagents

Virus-like Magnetic Mesoporous Silica Particles as a Universal Vaccination Platform against Pathogenic Infections

Authors: Mingyang Liu, Yan Zhao, Zhishang Shi, Jeffrey I Zink, Qilin Yu

Journal: ACS Nano

PubMed ID: 36961475

Doi: 10.1021/acsnano.3c00644

Products & Services: Gene Synthesis

Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants

Authors: Bin Ju, Qi Zhang, Ziyi Wang, Zhen Qin Aw, Peng Chen, Bing Zhou, Ruoke Wang, Xiangyang Ge, Qining Lv, Lin Cheng, Rui Zhang, Yi Hao Wong, Huixin Chen, Haiyan Wang, Sisi Shan, Xuejiao Liao, Xuanling Shi, Lei Liu, Justin Jang Hann Chu, Xinquan Wang, Zheng Zhang, Linqi Zhang

Journal: Nat Immunol

PubMed ID: 36914890

Doi: 10.1038/s41590-023-01449-6

Products & Services: DNA Sequencing

Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex

Authors: Peng Liu, Tian Xie, Xinyue Wu, Gongshe Han, Sita D Gupta, Zike Zhang, Jian Yue, Feitong Dong, Kenneth Gable, Somashekarappa Niranjanakumari, Wanyuan Li, Lin Wang, Wenchen Liu, Ruifeng Yao, Edgar B Cahoon, Teresa M Dunn, Xin Gong

Journal: SCIENCE ADVANCES

PubMed ID: 36989369

Doi: 10.1126/sciadv.adg0728

Products & Services: Proteins, Expression, Isolation and Analysis

Engineered production of isoprene from the model green microalga Chlamydomonas reinhardtii

Authors: Razan Z Yahya, Gordon B Wellman, Sebastian Overmans, Kyle J Lauersen

Journal: Metab Eng Commun .

PubMed ID: 37006831

Doi: 10.1016/j.mec.2023.e00221

Products & Services: Gene Synthesis

Epinecidin-1, a marine antifungal peptide, inhibits Botrytis cinerea and delays gray mold in postharvest peaches

Authors: Li Fan , Yingying Wei , Yi Chen , Shu Jiang , Feng Xu , Chundan Zhang , Hongfei Wang , Xingfeng Shao

Journal: Food Chem .

PubMed ID: 36191421

Doi: 10.1016/j.foodchem.2022.134419

Products & Services: Peptide Synthesis

Fabrication of bFGF/polydopamine-loaded PEEK implants for improving soft tissue integration by upregulating Wnt/β-catenin signaling

Authors: Xiaohu Wang, Ning Ma, Li Feng, Mingkui Shen, Yaqi Zhou, Xinan Zhang, Ruichao Huang, Li Zhou, Shanfeng Ji, Yongli Lou, Zhi Zhu

Journal: Heliyon

PubMed ID: 37012909

Doi: 10.1016/j.heliyon.2023.e14800

Products & Services: Proteins, Expression, Isolation and Analysis

Purification and biochemical characterization of a novel chitosanase cloned from the gene of Kitasatospora setae KM-6054 and its application in the production of chitooligosaccharides

Authors: Yinxiao Xu, Hui Wang, Benwei Zhu, Zhong Yao, Ling Jiang

Journal: World J Microbiol Biotechnol

PubMed ID: 36905451

Doi: 10.1007/s11274-023-03561-z

Products & Services: Proteins, Expression, Isolation and Analysis

Regenerative marine waste towards CaCO nanoformulation for Alzheimer's therapy

Authors: Prakashkumar Nallasamy, Beema Shafreen Rajamohamed, Jeyakanthan Jeyaraman, Brindhadevi Kathirvel, Suganthy Natarajan

Journal: Environ Res

PubMed ID: 36889568

Doi: 10.1016/j.envres.2023.115631

Products & Services: Peptide Synthesis

Enhanced Endosomal Signaling and Desensitization of GLP-1R vs GIPR in Pancreatic Beta Cells

Authors: Yusman Manchanda, Stavroula Bitsi, Shiqian Chen, Johannes Broichhagen, Jorge Bernardino de la Serna, Ben Jones, Alejandra Tomas

Journal: Endocrinology

PubMed ID: 36774542

Doi: 10.1210/endocr/bqad028

Products & Services: Molecular Biology Reagents

DELLA functions evolved by rewiring of associated transcriptional networks

Authors: Asier Briones-Moreno, Jorge Hernández-García, Carlos Vargas-Chávez, Noel Blanco-Touriñán, Alexandros Phokas, Cristina Úrbez, Pablo D Cerdán, Juliet C Coates, David Alabadí, Miguel A Blázquez

Journal: Nat Plants

PubMed ID: 36914897

Doi: 10.1038/s41477-023-01372-6

Products & Services: Gene Synthesis

Inflammatory stimulation of astrocytes affects the expression of miRNA-22-3p within NSCs-EVs regulating remyelination by targeting KDM3A

Authors: Tianyu Han, Peiwen Song, Zuomeng Wu, Cancan Wang, Yunlei Liu, Wang Ying, Kaixuan Li, Cailiang Shen

Journal: Stem Cell Res Ther

PubMed ID: 36959678

Doi: 10.1186/s13287-023-03284-w

Products & Services: Molecular Biology Reagents

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