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The molecular mechanism of light-induced bond formation and breakage in the cyanobacteriochrome TePixJ
Authors: Jeannette Ruf, Flavia Bindschedler, David Buhrke
Journal: Phys Chem Chem Phys
PubMed ID: 36752541
Doi: 10.1039/d2cp05856a
The molecular chaperone cysteine string protein is required for monomeric SNARE proteins to assemble in trans-complexes during human sperm acrosomal exocytosis†
Authors: Karina Flores-Montero, María Victoria Berberián, Luis Segundo Mayorga, Claudia Nora Tomes, María Celeste Ruete
Journal: Biol Reprod
PubMed ID: 36308432
Doi: 10.1093/biolre/ioac196
Characterization of a TatA/TatB binding site on the TatC component of the twin arginine translocase
Authors: Emmanuele Severi, Mariana Bunoro Batista, Adelie Lannoy, Phillip J Stansfeld, Tracy Palmer
Journal: Microbiology (Reading)
PubMed ID: 36790402
Doi: 10.1099/mic.0.001298
CriSNPr, a single interface for the curated and de novo design of gRNAs for CRISPR diagnostics using diverse Cas systems
Authors: Asgar H Ansari, Manoj Kumar, Sajal Sarkar, Souvik Maiti, Debojyoti Chakraborty
Journal: Elife
PubMed ID: 36752591
Doi: 10.7554/eLife.77976
Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit
Authors: Jonah Elliff, Aparna Biswas, Poonam Roshan, Sahiti Kuppa, Angela Patterson, Jenna Mattice, Mathivanan Chinnaraj, Ryan Burd, Sarah E Walker, Nicola Pozzi, Edwin Antony, Brian Bothner, Sofia Origanti
Journal: Nucleic Acids Res
PubMed ID: 36651285
Doi: 10.1093/nar/gkac1266
Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
Authors: Romain Rouet, Jake Y Henry, Matt D Johansen, Meghna Sobti, Harikrishnan Balachandran, David B Langley, Gregory J Walker, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Ohan Mazigi, Peter Schofield, Deborah L Burnett, Simon H J Brown, Marianne Martinello, Bernard Hudson, Nicole Gilroy, Jeffrey J Post, Anthony Kelleher, Hans-Martin Jäck, Christopher C Goodnow, Stuart G Turville, William D Rawlinson, Rowena A Bull, Alastair G Stewart, Philip M Hansbro, Daniel Christ
Journal: Nat Commun
PubMed ID: 36755042
Doi: 10.1038/s41467-023-36295-5
KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/β-Catenin Signaling Pathway
Authors: Ying Li, Yu Wang, Qinguang Zou, Shouqing Li, Fan Zhang
Journal: Lab Invest
PubMed ID: 36827869
Doi: 10.1016/j.labinv.2023.100078
Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine
Authors: Thayne H Dickey, Richi Gupta, Holly McAleese, Tarik Ouahes, Sachy Orr-Gonzalez, Rui Ma, Olga Muratova, Nichole D Salinas, Jen C C Hume, Lynn E Lambert, Patrick E Duffy, Niraj H Tolia
Journal: npj Vaccines
PubMed ID: 36808125
Doi: 10.1038/s41541-023-00619-9
Structure and dynamics of the EGFR/HER2 heterodimer
Authors: Xue Bai, Pengyu Sun, Xinghao Wang, Changkun Long, Shuyun Liao, Song Dang, Shangshang Zhuang, Yongtao Du, Xinyi Zhang, Nan Li, Kangmin He, Zhe Zhang
Journal: Cell Discov
PubMed ID: 36781849
Doi: 10.1038/s41421-023-00523-5
Epitopes in the Glycosylphosphatidylinositol Attachment Signal Peptide of Trypanosoma cruzi Mucin Proteins Generate Robust but Delayed and Nonprotective CD8+ T Cell Responses
Authors: Molly E Bunkofske, Natasha Perumal, Brooke White, Eva-Maria Strauch, Rick Tarleton
Journal: J Immunol
PubMed ID: 36603035
Doi: 10.4049/jimmunol.2200723
Products & Services: Molecular Biology Reagents   
Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A
Authors: Karolina Pavic, Nikhil Gupta, Judit Domènech Omella, Rita Derua, Anna Aakula, Riikka Huhtaniemi, Juha A Määttä, Nico Höfflin, Juha Okkeri, Zhizhi Wang, Otto Kauko, Roosa Varjus, Henrik Honkanen, Daniel Abankwa, Maja Köhn, Vesa P Hytönen, Wenqing Xu, Jakob Nilsson, Rebecca Page, Veerle Janssens, Alexander Leitner, Jukka Westermarck
Journal: Nat Commun
PubMed ID: 36854761
Doi: 10.1038/s41467-023-36693-9
Products & Services: Molecular Biology Reagents   
Big data mining, rational modification, and ancestral sequence reconstruction inferred multiple xylose isomerases for biorefinery
Authors: Sitong Chen, Zhaoxian Xu, Boning Ding, Yuwei Zhang, Shuangmei Liu, Chenggu Cai, Muzi Li, Bruce E Dale, Mingjie Jin
Journal: Sci Adv
PubMed ID: 36724227
Doi: 10.1126/sciadv.add8835
Products & Services: Molecular Biology Reagents   
Network of hotspot interactions cluster tau amyloid folds
Authors: Vishruth Mullapudi, Jaime Vaquer-Alicea, Vaibhav Bommareddy, Anthony R Vega, Bryan D Ryder, Charles L White, Marc I Diamond, Lukasz A Joachimiak
Journal: Nat Commun
PubMed ID: 36797278
Doi: 10.1038/s41467-023-36572-3
Products & Services: Peptide Synthesis   
Engineered biocontainable RNA virus vectors for non-transgenic genome editing across crop species and genotypes
Authors: Qian Liu, Chenglu Zhao, Kai Sun, Yinlu Deng, Zhenghe Li
Journal: Mol Plant
PubMed ID: 36751129
Doi: 10.1016/j.molp.2023.02.003
Products & Services: Peptide Synthesis   
Efficient hydroxylation of flavonoids by using whole-cell P450 sca-2 biocatalyst in
Authors: Baodong Hu, Xinrui Zhao, Jingwen Zhou, Jianghua Li, Jian Chen, Guocheng Du
Journal: Front Bioeng Biotechnol
PubMed ID: 36873357
Doi: 10.3389/fbioe.2023.1138376
Products & Services: Gene Synthesis   
Fused human paraoxonase 1 as a prophylactic agent against organophosphate poisoning
Authors: Prakashkumar Dobariya, Pratik Adhya, Bhupesh Vaidya, Prakash Y Khandave, Shyam Sunder Sharma, Abhay H Pande
Journal: Enzyme Microb Technol
PubMed ID: 36764031
Doi: 10.1016/j.enzmictec.2023.110209
Products & Services: Molecular Biology Reagents   
Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions
Authors: Arun Kumar Somavarapu, Giulia Kleijwegt, Madhu Nagaraj, Parvez Alam, Janni Nielsen, Daniel E Otzen
Journal: Chem Sci
PubMed ID: 36937574
Doi: 10.1039/d2sc05534a
Products & Services: Recombinant Proteins   
A rapid nucleic acid detection platform based on phosphorothioate-DNA and sulfur binding domain
Authors: Yuting Shuai, Yi Ju, Yuanhang Li, Dini Ma, Lan Jiang, Jingyu Zhang, Gao-Yi Tan, Xueting Liu, Shenlin Wang, Lixin Zhang, Guang Liu
Journal: Synth Syst Biotechnol
PubMed ID: 36875498
Doi: 10.1016/j.synbio.2023.02.002
Cas12a-based one-pot SNP detection with high accuracy
Authors: Hong-Xia Zhang, Caixiang Zhang, Shuhan Lu, Xiaohan Tong, Kun Zhang, Hao Yin, Ying Zhang
Journal: Cell Insight
PubMed ID: 37193068
Doi: 10.1016/j.cellin.2023.100080
Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice
Authors: Honghui Liu, Lili Wu, Bo Liu, Ke Xu, Wenwen Lei, Jianguo Deng, Xiaoyu Rong, Pei Du, Lebing Wang, Dongbin Wang, Xiaolong Zhang, Chao Su, Yuhai Bi, Hua Chen, William J Liu, Jianxun Qi, Qingwei Cui, Shuhui Qi, Ruiwen Fan, Jingkun Jiang, Guizhen Wu, George F Gao, Qihui Wang
Journal: cell reports. medicine
PubMed ID: 36702124
Doi: 10.1016/j.xcrm
Products & Services: Gene Synthesis   
Siglec-9 Restrains Antibody-Dependent Natural Killer Cell Cytotoxicity against SARS-CoV-2
Authors: Pratima Saini, Opeyemi S Adeniji, Devivasha Bordoloi, Jennifer Kinslow, Jeff Martinson, Danielle M Parent, Kai Ying Hong, Jane Koshy, Abhijeet J Kulkarni, Netanel F Zilberstein, Robert A Balk, James N Moy, Leila B Giron, Russell P Tracy, Ali Keshavarzian, Kar Muthumani, Alan Landay, David B Weiner, Mohamed Abdel-Mohsen
Journal: MBio
PubMed ID: 36728420
Doi: 10.1128/mbio.03393-22
Cathepsin H and cathepsin B of Cynoglossus semilaevis are involved in anti-bacterial immunity against Edwardsiella tarda
Authors: Yilong Wang, Hang Xu, Boguang Sun
Journal: Fish Shellfish Immunol
PubMed ID: 36754156
Doi: 10.1016/j.fsi.2023.108594
Molecular basis of RADAR anti-phage supramolecular assemblies
Authors: Yina Gao, Xiu Luo, Peipei Li, Zhaolong Li, Feng Ye, Songqing Liu, Pu Gao
Journal: Cell
PubMed ID: 36764292
Doi: 10.1016/j.cell.2023.01.026
Insights into the oligomeric structure of the HIV-1 Vpu protein
Authors: Saman Majeed, Oluwatosin Adetuyi, Peter P Borbat, Md Majharul Islam, Olamide Ishola, Bo Zhao, Elka R Georgieva
Journal: J Struct Biol
PubMed ID: 36796461
Doi: 10.1016/j.jsb.2023.107943
Products & Services: Molecular Biology Reagents   
Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression
Authors: Nicholas J Tursi, Ziyang Xu, Michaela Helble, Susanne Walker, Kevin Liaw, Neethu Chokkalingam, Toshitha Kannan, Yuanhan Wu, Edgar Tello-Ruiz, Daniel H Park, Xizhou Zhu, Megan C Wise, Trevor R F Smith, Sonali Majumdar, Andrew Kossenkov, Daniel W Kulp, David B Weiner
Journal: Front Immunol
PubMed ID: 36911698
Doi: 10.3389/fimmu.2023.1072810
Products & Services: Molecular Biology Reagents   
Transcriptional dynamics of maize leaves, pollens and ovules to gain insights into heat stress-related responses
Authors: Ashok Babadev Jagtap, Inderjit Singh Yadav, Yogesh Vikal, Umesh Preethi Praba, Navneet Kaur, Adeshpal Singh Gill, Gurmukh S Johal
Journal: Front Plant Sci
PubMed ID: 36875566
Doi: 10.3389/fpls.2023.1117136
Products & Services: PCR Cloning and Subcloning   
A Balance between Pro-Inflammatory and Pro-Reparative Macrophages is Observed in Regenerative D-MAPS
Authors: Yining Liu, Alejandra Suarez-Arnedo, Shamitha Shetty, Yaoying Wu, Michelle Schneider, Joel H Collier, Tatiana Segura
Journal: Adv Sci (Weinh)
PubMed ID: 36762570
Doi: 10.1002/advs.202204882
Products & Services: Peptide Synthesis   
A novel role for trithorax in the gene regulatory network for a rapidly evolving fruit fly pigmentation trait
Authors: Michael L Weinstein, Chad M Jaenke, Hasiba Asma, Matthew Spangler, Katherine A Kohnen, Claire C Konys, Melissa E Williams, Ashley V Williams, Mark Rebeiz, Marc S Halfon, Thomas M Williams
Journal: PLoS Genet
PubMed ID: 36795790
Doi: 10.1371/journal.pgen.1010653
Products & Services: DNA Sequencing   
Biomineralization inspired 3D printed bioactive glass nanocomposite scaffolds orchestrate diabetic bone regeneration by remodeling micromilieu
Authors: Zeqian Xu, Xuanyu Qi, Minyue Bao, Tian Zhou, Junfeng Shi, Zhiyan Xu, Mingliang Zhou, Aldo R Boccaccini, Kai Zheng, Xinquan Jiang
Journal: Bioact Mater
PubMed ID: 36817824
Doi: 10.1016/j.bioactmat.2023.01.024
Products & Services: Custom RNAi Services   
Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM
Authors: Airah Javorsky, Janesha C Maddumage, Emily R R Mackie, Tatiana P Soares da Costa, Patrick O Humbert, Marc Kvansakul
Journal: The FEBS journal
PubMed ID: 36029163
Doi: 10.1111/febs.16607
Products & Services: Peptide Synthesis   
Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination
Authors: Huasong Ai, Zebin Tong, Zhiheng Deng, Jiakun Tian, Liying Zhang, Maoshen Sun, Yunxiang Du, Ziyu Xu, Qiang Shi, Lujun Liang, Qingyun Zheng, Jia-Bin Li, Man Pan, and Lei Liu
Journal: Chem
Doi: 10.1016/j.chempr.2023.01.012
Products & Services: Gene Synthesis   
Site-specific labeling of SBDS to monitor interactions with the 60S ribosomal subunit
Authors: Aparna Biswas, Yu-Fong Peng, Vikas Kaushik, Sofia Origanti
Journal: Methods
PubMed ID: 36781034
Doi: 10.1016/j.ymeth.2023.02.004
The endogenous repertoire harbors self-reactive CD4 T cell clones that adopt a follicular helper T cell-like phenotype at steady state
Authors: Victoria Lee, Donald M Rodriguez, Nicole K Ganci, Sharon Zeng, Junting Ai, Jaime L Chao, Matthew T Walker, Christine H Miller, David E J Klawon, Mary H Schoenbach, Domenick E Kennedy, Mark Maienschein-Cline, Nicholas D Socci, Marcus R Clark, Peter A Savage
Journal: Nat Immunol
PubMed ID: 36759711
Doi: 10.1038/s41590-023-01425-0
Products & Services: Molecular Biology Reagents   
Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria
Authors: Aidan J Preston, Aaron Rogers, Miranda Sharp, Gareth Mitchell, Cristhian Toruno, Brayden B Barney, Lauren N Donovan, Journey Bly, Ryan Kennington, Emily Payne, Anthony Iovino, Gabriela Furukawa, Rosann Robinson, Bahar Shamloo, Matthew Buccilli, Rachel Anders, Sarah Eckstein, Elizabeth A Fedak, Tanner Wright, Carlo C Maley, Wendy K Kiso, Dennis Schmitt, David Malkin, Joshua D Schiffman, Lisa M Abegglen
Journal: Cell Death Discov
PubMed ID: 36797268
Doi: 10.1038/s41420-023-01348-7
Products & Services: Molecular Biology Reagents   
Soluble adenylyl cyclase coordinates intracellular pH homeostasis and biomineralization in calcifying cells of a marine animal
Authors: William Weijen Chang, Angus B Thies, Martin Tresguerres, Marian Y Hu
Journal: Am J Physiol Cell Physiol
PubMed ID: 36779665
Doi: 10.1152/ajpcell.00524.2022
Products & Services: Peptide Synthesis   
Structure of metallochaperone in complex with the cobalamin-binding domain of its target mutase provides insight into cofactor delivery
Authors: Francesca A Vaccaro, David A Born, Catherine L Drennan
Journal: Proc Natl Acad Sci U S A
PubMed ID: 36787360
Doi: 10.1073/pnas.2214085120
Products & Services: Insect Expression   
The antibacterial activity and antibacterial mechanism analyses of an LRR-IG protein in the Chinese mitten crab, Eriocheir sinensis
Authors: Yi Zhang, Yunhui Bai, Qiao Shi, Bin Zhou, Mengqi Ni, Jinbin Zheng, Zhaoxia Cui
Journal: Int J Biol Macromol
PubMed ID: 36801302
Doi: 10.1016/j.ijbiomac.2023.123732
New Monoclonal Antibodies Specific for Different Epitopes of the Spike Protein of SARS-CoV-2 and Its Major Variants: Additional Tools for a More Specific COVID-19 Diagnosis
Authors: Sabrina Mariotti, Maria Vincenza Chiantore, Raffaela Teloni, Angelo Iacobino, Antonio Capocefalo, Zuleika Michelini, Martina Borghi, Melissa Baggieri, Antonella Marchi, Paola Bucci, Silvia Gioacchini, Raffaele D'Amelio, Philip J M Brouwer, Silvia Sandini, Chiara Acchioni, Marco Sgarbanti, Antonio Di Virgilio, Felicia Grasso, Andrea Cara, Donatella Negri, Fabio Magurano, Paola Di Bonito, Roberto Nisini
Journal: Biomedicines
PubMed ID: 36831149
Doi: 10.3390/biomedicines11020610
Hyperoxia exposure upregulates Dvl-1 and activates Wnt/β-catenin signaling pathway in newborn rat lung
Authors: Yuting Zhu, Yawen Li, Weilai Jin, Zhengying Li, Le Zhang, Yuanyuan Fang, Yanyu Zhang
Journal: BMC Mol Cell Biol
PubMed ID: 36726071
Doi: 10.1186/s12860-023-00465-6
Products & Services: Catalog Peptides   
EGF‑IL2 bispecific and bivalent EGF fusion toxin efficacy against syngeneic head and neck cancer mouse models
Authors: Yue Qiu , Zeng Qi , Zhaohui Wang , Yu Cao , Ling Lu , Huiping Zhang , David Mathes , Elizabeth A Pomfret , Shi-Long Lu , Zhirui Wang
Journal: Oncol Rep
PubMed ID: 36579667
Doi: 10.3892/or.2022.8474
Products & Services: Gene Synthesis   
Novel csuC-DNA nanovaccine based on chitosan candidate vaccine against infection with Acinetobacter baumannii
Authors: Eskandar Hosseinnezhad-Lazarjani, Abbas Doosti, Ali Sharifzadeh
Journal: Vaccine
PubMed ID: 36841724
Doi: 10.1016/j.vaccine.2023.02.046
DNA aptamer-based affinity chromatography system for purification of recombinant proteins tagged with lysine tag
Authors: Klaudia Arciszewska, Ewa Kowalska, Filip Bartnicki, Piotr Bonarek, Agnieszka Katarzyna Banaś, Wojciech Strzałka
Journal: J Chromatogr A
PubMed ID: 36780846
Doi: 10.1016/j.chroma.2023.463846
Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2
Authors: Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang
Journal: J Virol
PubMed ID: 36779763
Doi: 10.1128/jvi.01611-22
Products & Services: Catalog Antibody   
Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity
Authors: Mark C Wagner, Ruben M Sandoval, Shiv Pratap S Yadav, Silvia B Campos, George J Rhodes, Carrie L Phillips, Bruce A Molitoris
Journal: Kidney360
PubMed ID: 36848531
Doi: 10.34067/KID.0000000000000094
Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection
Authors: Alan T Tang, David W Buchholz, Katherine M Szigety, Brian Imbiakha, Siqi Gao, Maxwell Frankfurter, Min Wang, Jisheng Yang, Peter Hewins, Patricia Mericko-Ishizuka, N Adrian Leu, Stephanie Sterling, Isaac A Monreal, Julie Sahler, Avery August, Xuming Zhu, Kellie A Jurado, Mingang Xu, Edward E Morrisey, Sarah E Millar, Hector C Aguilar, Mark L Kahn
Journal: PLoS Biol
PubMed ID: 36745682
Doi: 10.1371/journal.pbio.3001989
A biallelic loss of function variant in HORMAD1 within a large consanguineous Turkish family is associated with spermatogenic arrest
Authors: Ozlem Okutman, Manon Boivin, Jean Muller, Nicolas Charlet-Berguerand, Stéphane Viville
Journal: Hum Reprod
PubMed ID: 36524333
Doi: 10.1093/humrep/deac259
Celastrol alleviates oxidative stress induced by multi-walled carbon nanotubes through the Keap1/Nrf2/HO-1 signaling pathway
Authors: Tao-Lin Qing, Lang Yan, Shao-Kang Wang, Xiao-Yu Dai, Li-Jun Ren, Ji-Qian-Zhu Zhang, Wen-Jing Shi, Xiao-Fang Zhang, Mei-Tang Wang, Ji-Kuai Chen, Jiang-Bo Zhu
Journal: Ecotoxicol Environ Saf
PubMed ID: 36774793
Doi: 10.1016/j.ecoenv.2023.114623
Products & Services: Molecular Biology Reagents   
Synthesis of Bispecific Antibody Conjugates Using Functionalized Poly-ADP-ribose Polymers
Authors: Qinqin Cheng, Xiao-Nan Zhang, Jiawei Li, Jingwen Chen, Yiling Wang, Yong Zhang
Journal: Biochemistry
PubMed ID: 36821831
Doi: 10.1021/acs.biochem.2c00718
Products & Services: Molecular Biology Reagents   
Multicopy suppressor screens reveal convergent evolution of single-gene lysis proteins
Authors: Benjamin A Adler, Karthik Chamakura, Heloise Carion, Jonathan Krog, Adam M Deutschbauer, Ry Young, Vivek K Mutalik, Adam P Arkin
Journal: Nat Chem Biol
PubMed ID: 36805702
Doi: 10.1038/s41589-023-01269-7
Products & Services: Plasmid DNA Preparation   
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase
Authors: Carlo Rinaldi, Paolo Pizzul, Erika Casari, Marco Mangiagalli, Renata Tisi, Maria Pia Longhese
Journal: Nucleic Acids Res
PubMed ID: 36762474
Doi: 10.1093/nar/gkad062
Products & Services: Gene Synthesis   

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