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Sulforaphane alleviates the meiosis defects induced by 3-nitropropionic acid in mouse oocytes

Authors: Wei-Jian Li, Xuan Zhang, Ming Shen, Hong-Lin Liu, Li-Ren Ding

Journal: Food Chem Toxicol

PubMed ID: 37783421

Doi: 10.1016/j.fct.2023.114083

Products & Services: Molecular Biology Reagents

Identification and evaluation in-vitro of conserved peptides with high affinity to MHC-I as potential protective epitopes for Newcastle disease virus vaccines

Authors: Luis Tataje-Lavanda, Edith Málaga, Manuela Verastegui, Egma Mayta Huatuco, Eliana Icochea, Manolo Fernández-Díaz, Mirko Zimic

Journal: BMC Vet Res

PubMed ID: 37805566

Doi: 10.1186/s12917-023-03726-w

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Discovering human cell-compatible gene therapy virus variants via optimized screening in mouse models

Authors: Moyu Dai, Ning Yang, Kai Xu, Jingwen Zhang, Xueke Li, Ying Zhang, Wei Li

Journal: Cell Prolif

PubMed ID: 37864397

Doi: 10.1111/cpr.13565

Products & Services: Protein and Antibody Isolation

A novel metalloproteinase-derived cryptide from Bothrops cotiara venom inhibits angiotensin-converting enzyme activity

Authors: Jackson Gabriel Miyamoto, Eduardo Shigueo Kitano, André Zelanis, Pedro Gabriel Nachtigall, Inácio Junqueira-de-Azevedo, Sávio Stefanini Sant'Anna, Rogério Lauria da Silva, Patrícia Alessandra Bersanetti, Adriana Karaoglanovic Carmona, Pedro José Barbosa Pereira, Solange M T Serrano, Maria Luiza Vilela Oliva, Alexandre Keiji Tashima

Journal: Biochimie

PubMed ID: 37839625

Doi: 10.1016/j.biochi.2023.10.010

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Requires the Type II Secretion System for Pathogenicity and Survival in Grapevine

Authors: Brian Ingel, Claudia Castro, Lindsey Burbank, Nancy Her, N Itzel De Anda, Hannah Way, Peng Wang, M Caroline Roper

Journal: Mol Plant Microbe Interact

PubMed ID: 37188464

Doi: 10.1094/MPMI-03-23-0027-R

Products & Services: Gene Synthesis

Molecular mechanism of decision-making in glycosaminoglycan biosynthesis

Authors: Douglas Sammon, Anja Krueger, Marta Busse-Wicher, Rhodri Marc Morgan, Stuart M Haslam, Benjamin Schumann, David C Briggs, Erhard Hohenester

Journal: Nat Commun

PubMed ID: 37828045

Doi: 10.1038/s41467-023-42236-z

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A morpheein equilibrium regulates catalysis in phosphoserine phosphatase SerB2 from Mycobacterium tuberculosis

Authors: Elise Pierson, Florian De Pol, Marianne Fillet, Johan Wouters

Journal: Commun Biol

PubMed ID: 37817000

Doi: 10.1038/s42003-023-05402-z

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Aggregative adherence fimbriae form compact structures as seen by SAXS

Authors: Rie Jønsson, Alexander Björling, Søren Roi Midtgaard, Grethe Vestergaard Jensen, Nicholas Skar-Gislinge, Lise Arleth, Steve Matthews, Karen Angeliki Krogfelt, Håvard Jenssen

Journal: Sci Rep

PubMed ID: 37783694

Doi: 10.1038/s41598-023-42079-0

Products & Services: Protein and Antibody Isolation

Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases

Authors: Shaojie Cui, Anchal Ghai, Yaqin Deng, Shili Li, Ruihui Zhang, Christopher Egbulefu, Guosheng Liang, Samuel Achilefu, Jin Ye

Journal: Mol Cell

PubMed ID: 37863053

Doi: 10.1016/j.molcel.2023.09.025

Products & Services: Molecular Biology Reagents

Differential modulation of cellular phenotype and drug sensitivity by extracellular matrix proteins in primary and metastatic pancreatic cancer cells

Authors: Olalekan H Usman, Sampath Kumar, Reddick R Walker, Gengqiang Xie, Hyeje C Sumajit, AbdelAziz R Jalil, Subramanian Ramakrishnan, Lawrence J Dooling, Yue Julia Wang, Jerome Irianto

Journal: Mol Biol Cell

PubMed ID: 37903222

Doi: 10.1091/mbc.E23-02-0075

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Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae

Authors: Yu-Min Li, Yu-Chao Mei, Ao-Hui Liu, Ru-Xin Wang, Runfa Chen, Hai-Ning Du

Journal: Cell Rep

PubMed ID: 37796660

Doi: 10.1016/j.celrep.2023.113186

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Loss of ATG4B and ATG4A results in two-stage cell cycle defects in pancreatic ductal adenocarcinoma cells

Authors: Paalini Sathiyaseelan, Suganthi Chittaranjan, Steve E Kalloger, Jennifer Chan, Nancy E Go, Mario A Jardon, Cally J Ho, Theodore Hui, Jing Xu, Christine Chow, Dongxia Gao, Fraser D Johnson, William W Lockwood, Gregg B Morin, Daniel J Renouf, David F Schaeffer, Sharon M Gorski

Journal: J Cell Sci

PubMed ID: 37701987

Doi: 10.1242/jcs.260644

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Propofol Promoted the Cell Growth and Epithelial Mesenchymal Transformation of the HTR-8/SVneo Cells through Targeting the METTL3 Mediated ZEB2

Authors: Long Cheng, Liang Zhao, Geng Wang

Journal: Reprod Sci

PubMed ID: 37814200

Doi: 10.1007/s43032-023-01368-9

Products & Services: Molecular Biology Reagents

Development of a counterselectable system for rapid and efficient CRISPR-based genome engineering in Zymomonas mobilis

Authors: Yanli Zheng, Hongmei Fu, Jue Chen, Jie Li, Yuejie Bian, Ping Hu, Lei Lei, Yihan Liu, Jiangke Yang, Wenfang Peng

Journal: Microb Cell Fact

PubMed ID: 37833755

Doi: 10.1186/s12934-023-02217-9

Products & Services: Protein and Antibody Isolation

Recombinant adeno-associated virus production evaluation in Chinese hamster ovary cells

Authors: Thu M Cao, Dayue Chen, Gavin C Barnard, Amy Shen

Journal: Biotechnol Bioeng

PubMed ID: 37902721

Doi: 10.1002/bit.28578

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Author Correction: Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses

Authors: Xiuyuan Ou, Ge Xu, Pei Li, Yan Liu, Fuwen Zan, Pan Liu, Jiaxin Hu, Xing Lu, Siwen Dong, Yao Zhou, Zhixia Mu, Zhiqiang Wu, Jianwei Wang, Qi Jin, Pinghuang Liu, Jian Lu, Xiangxi Wang, Zhaohui Qian

Journal: Cell Discov

PubMed ID: 37813850

Doi: 10.1038/s41421-023-00597-1

Products & Services: Protein and Antibody Isolation

G-quadruplexes of KSHV oriLyt play important roles in promoting lytic DNA replication

Authors: Prerna Dabral, Timsy Uppal, Subhash C Verma

Journal: Microbiol Spectr

PubMed ID: 37800915

Doi: 10.1128/spectrum.05316-22

Products & Services: Protein and Antibody Isolation

Intradermal DNA vaccine delivery using vacuum-controlled, needle-free electroporation

Authors: Alison Generotti, Ryne Contreras, Brenden Zounes, Eric Schade, Andrea Kemme, Yatish Rane, Xinggang Liu, Dustin Elwood, Katherine Schultheis, Jeremy Marston, Jay McCoy, Kate Broderick, Paul Fisher

Journal: Mol Ther Nucleic Acids

PubMed ID: 38034030

Doi: 10.1016/j.omtn.2023.102070

Products & Services: Peptide Synthesis

Expression of a SAG protein with a CAP domain from Eimeria necatrix and its role in invasion and immunoprotection

Authors: Feiyan Wang, Amin Zhang, Xuelian Fan, Qianqian Feng, Zhizhi Zhang, Dandan Liu, Shijie Su, Zhaofeng Hou, Jinjun Xu, Xilong Kang, Zhiming Pan, Hunjie Hu, Jianping Tao

Journal: Vet Parasitol

PubMed ID: 37931477

Doi: 10.1016/j.vetpar.2023.110060

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A two-arm analysis of the immune response to heterologous boosting of inactivated SARS-CoV-2 vaccines

Authors: Arnone Nithichanon, Ludthawun Kamuthachad, Kanin Salao, Wisitsak Phoksawat, Chatcharin Kamsom, Surasakdi Wongratanacheewin, Chonlatip Pipattanaboon, Sakawrat Kanthawong, Umaporn Yordpratum, Sirinart Aromseree, Atibordee Meesing, Piroon Mootsikapun, Steven W Edwards, Supranee Phanthanawiboon

Journal: Sci Rep

PubMed ID: 37907584

Doi: 10.1038/s41598-023-46053-8

Products & Services: Molecular Biology Reagents

Antibodies elicited by Plasmodium falciparum circumsporozoite proteins lacking sequentially deleted C-terminal amino acids reveal mouse strain and epitopes specific differences

Authors: Clifford T H Hayashi, Yi Cao, Fidel Zavala, Hayk Simonyan, Colin N Young, Nirbhay Kumar

Journal: Vaccine

PubMed ID: 37827976

Doi: 10.1016/j.vaccine.2023.10.009

Products & Services: Gene Synthesis

Structural and functional characterization of Aedes aegypti pupal cuticle protein that controls dengue virus infection

Authors: Qingqing Huang, Edem Gavor, Nikhil Kumar Tulsian, Jingsong Fan, Qingsong Lin, Yu Keung Mok, R Manjunatha Kini, J Sivaraman

Journal: Protein Sci

PubMed ID: 37593853

Doi: 10.1002/pro.4761

Products & Services: Codon Optimization

DETECTION OF SARS-COV-2 NEUTRALIZING ANTIBODIES IN RETROPHARYNGEAL LYMPH NODE EXUDATES OF WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) FROM NEBRASKA, USA

Authors: Korakrit Poonsuk, Duan Loy, Rachael Birn, Bryan Buss, Matthew Donahue, Todd Nordeen, Kylie Sinclair, Luke Meduna, Bruce Brodersen, John Dustin Loy

Journal: J Wildl Dis

PubMed ID: 37768779

Doi: 10.7589/JWD-D-23-00005

Products & Services: Protein and Antibody Isolation

MpADC, an L-aspartate-α-decarboxylase, from Myzus persicae, that enables production of β-alanine with high yield by whole-cell enzymatic catalysis

Authors: Pengfu Liu, Saixue Xie, Qian Guo, Yan Chen, Junying Fan, Ashok Kumar Nadda, Xiaoluo Huang, Xiaohe Chu

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 37876019

Doi: 10.1186/s13068-023-02405-0

Products & Services: Protein and Antibody Isolation

Chemoproteomic capture of RNA binding activity in living cells

Authors: Andrew J Heindel, Jeffrey W Brulet, Xiantao Wang, Michael W Founds, Adam H Libby, Dina L Bai, Michael C Lemke, David M Leace, Thurl E Harris, Markus Hafner, Ku-Lung Hsu

Journal: Nat Commun

PubMed ID: 37805600

Doi: 10.1038/s41467-023-41844-z

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Novel ADAMTS13 mutations in a patient with congenital thrombotic thrombocytopenic purpura

Authors: Zhitao Wang, Xinhui Zhang, Xueqin Lu, Peng Peng, Huiru Wang, Shanglong Feng, Li Zhou

Journal: Hematology

PubMed ID: 37850618

Doi: 10.1080/16078454.2023.2269513

Products & Services: Protein and Antibody Isolation

Authentication of a lophotrochozoan adipokinetic hormone receptor in a Gastropod, Aplysia californica

Authors: Pei-San Tsai, Kelsey N Sanders, Xin Dai, David Plachetzki

Journal: Gen Comp Endocrinol

PubMed ID: 37865149

Doi: 10.1016/j.ygcen.2023.114393

Products & Services: Molecular Biology Reagents

Investigation of Immunostimulatory Effects of IFN-γ Cytokine and CD40 Ligand Costimulatory Molecule for Development of HIV-1 Therapeutic Vaccine Candidate

Authors: Fatemeh Heidarnejad, Azam Bolhassani, Soheila Ajdary, Alireza Milani, Seyed Amir Sadeghi

Journal: Adv Biol (Weinh)

PubMed ID: 37840398

Doi: 10.1002/adbi.202300402

Products & Services: Molecular Biology Reagents

The cell-end protein Tea4 spatially regulates hyphal branch initiation and appressorium remodeling in the blast fungus

Authors: Audra Mae Rogers, Rachel Taylor, Martin John Egan

Journal: Mol Biol Cell

PubMed ID: 37903237

Doi: 10.1091/mbc.E23-06-0214

Products & Services: PCR Cloning and Subcloning

Cryo-EM structure of severe fever with thrombocytopenia syndrome virus

Authors: Shouwen Du, Ruchao Peng, Wang Xu, Xiaoyun Qu, Yuhang Wang, Jiamin Wang, Letian Li, Mingyao Tian, Yudong Guan, Jigang Wang, Guoqing Wang, Hao Li, Lingcong Deng, Xiaoshuang Shi, Yidan Ma, Fengting Liu, Minhua Sun, Zhengkai Wei, Ningyi Jin, Wei Liu, Jianxun Qi, Quan Liu, Ming Liao, Chang Li

Journal: Nat Commun

PubMed ID: 37816705

Doi: 10.1038/s41467-023-41804-7

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SARS-CoV-2 infection of human lung epithelial cells induces TMPRSS-mediated acute fibrin deposition

Authors: Rachel Erickson, Chang Huang, Cameron Allen, Joanna Ireland, Gwynne Roth, Zhongcheng Zou, Jinghua Lu, Bernard A P Lafont, Nicole L Garza, Beniah Brumbaugh, Ming Zhao, Motoshi Suzuki, Lisa Olano, Joseph Brzostowski, Elizabeth R Fischer, Homer L Twigg, Reed F Johnson, Peter D Sun

Journal: Nat Commun

PubMed ID: 37821447

Doi: 10.1038/s41467-023-42140-6

Products & Services: Gene Synthesis

Specific Nucleotides in the Common Region of the Begomovirus Tomato Rugose Mosaic Virus (ToRMV) Are Responsible for the Negative Interference over Tomato Severe Rugose Virus (ToSRV) in Mixed Infection

Authors: Angélica M Nogueira, Tarsiane M C Barbosa, Ayane F F Quadros, Anelise F Orílio, Marcela C J Bigão, César A D Xavier, Camila G Ferro, Francisco Murilo Zerbini

Journal: Viruses

PubMed ID: 37896851

Doi: 10.3390/v15102074

Products & Services: Recombinant Proteins

Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs

Authors: Ghasidit Pornnoppadol, Layne G Bond, Michael J Lucas, Jennifer M Zupancic, Yun-Huai Kuo, Boya Zhang, Colin F Greineder, Peter M Tessier

Journal: Cell Chem Biol

PubMed ID: 37890480

Doi: 10.1016/j.chembiol.2023.09.008

Products & Services: Combinatorial Mutant library

Lactate promotes intracellular replication and systemic infection via driving macrophage M2 polarization

Authors: Xinyue Wang, Bin Yang, Shuangshuang Ma, Xiaolin Yan, Shuai Ma, Hongmin Sun, Yuyang Sun, Lingyan Jiang

Journal: Microbiol Spectr

PubMed ID: 37796020

Doi: 10.1128/spectrum.02253-23

Products & Services: PCR Cloning and Subcloning

Tetravalent SARS-CoV-2 S1 subunit protein vaccination elicits robust humoral and cellular immune responses in SIV-infected rhesus macaque controllers

Authors: Muhammad S Khan, Eun Kim, Quentin Le Hingrat, Adam Kleinman, Alessandro Ferrari, Jose C Sammartino, Elena Percivalle, Cuiling Xu, Shaohua Huang, Thomas W Kenniston, Irene Cassaniti, Fausto Baldanti, Ivona Pandrea, Andrea Gambotto, Cristian Apetrei

Journal: MBio

PubMed ID: 37830800

Doi: 10.1128/mbio.02070-23

Products & Services: Molecular Biology Reagents

Flavivirus genome recoding by codon optimisation confers genetically stable in vivo attenuation in both mice and mosquitoes

Authors: Wei-Xin Chin, Hao Yuin Kong, Isabelle Xin Yu Zhu, Zi Yun Teo, Regina Faruk, Regina Ching Hua Lee, Si Xian Ho, Zhen Qin Aw, Bowen Yi, Xin Jun Hou, Antson Kiat Yee Tan, Thinesshwary Yogarajah, Roland G Huber, Yu Cai, Yue Wan, Justin Jang Hann Chu

Journal: PLoS Pathog

PubMed ID: 37883598

Doi: 10.1371/journal.ppat.1011753

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Proteomic Analysis Reveals a PLK1-Dependent G2/M Degradation Program and Links PKA-AKAP2 to Cell Cycle Control

Authors: Ryan D Mouery, Carolyn Hsu, Thomas Bonacci, Derek L Bolhuis, Xianxi Wang, Christine A Mills, E Drew Toomer, Owen G Canterbury, Kevin C Robertson, Timothy B Branigan, Nicholas G Brown, Laura E Herring, Michael J Emanuele

Journal: biorxiv

PubMed ID: 37873169

Doi: 10.1101/2023.10.11.561963

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Improved Stability and Manufacturability of Nucleocapsid Antigens for SARS-CoV2 Diagnostics through Protein Engineering

Authors: Esha Shukla, Lipsa Choudhury, Saurabh Rastogi, Arshmeet Chawla, Sanghati Bhattacharya, Umesh Kaushik, Manan Mittal, Anurag Singh Rathore, Gaurav Pandey

Journal: Biomolecules

PubMed ID: 37892206

Doi: 10.3390/biom13101524

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Quercetin ameliorates ferroptosis of rat cardiomyocytes via activation of the SIRT1/p53/SLC7A11 signaling pathway to alleviate sepsis‑induced cardiomyopathy

Authors: Xin Lin, Xiaoxia Zhao, Qingfeng Chen, Xiaoyue Wang, Yongya Wu, Hao Zhao

Journal: Int J Mol Med

PubMed ID: 37859612

Doi: 10.3892/ijmm.2023.5319

Products & Services: Protein and Antibody Isolation

Evaluation of potential targets to enhance the sensitivity of cholangiocarcinoma cells to anticancer drugs

Authors: Paula Sanchon-Sanchez, Oscar Briz, Rocio I R Macias, Mar Abad, Anabel Sanchez-Martin, Jose J G Marin, Elisa Lozano

Journal: Biomed Pharmacother

PubMed ID: 37832404

Doi: 10.1016/j.biopha.2023.115658

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Modulating biofilm can potentiate activity of novel plastic-degrading enzymes

Authors: Sophie A Howard, Ronan R McCarthy

Journal: NPJ Biofilms Microbiomes

PubMed ID: 37788986

Doi: 10.1038/s41522-023-00440-1

Products & Services: Gene Synthesis

Differential regulation of fibronectin expression and fibrillogenesis by autocrine TGF-β1 signaling in malignant and benign mammary epithelial cells

Authors: Michael M Sofroniou, Christopher A Lemmon

Journal: Int J Biochem Cell Biol

PubMed ID: 37866655

Doi: 10.1016/j.biocel.2023.106478

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Development of CRISPR/Cas9-Based Genome Editing Tools for Polyploid Yeast Cyberlindnera jadinii and Its Application in Engineering Heterologous Steroid-Producing Strains

Authors: Lishan Gu, Rongxin Zhang, Xuqian Fan, Yu Wang, Kaiyu Ma, Jingjing Jiang, Gen Li, Honglei Wang, Feiyu Fan, Xueli Zhang

Journal: ACS Synth Biol

PubMed ID: 37816156

Doi: 10.1021/acssynbio.3c00278

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Identification and production of novel potential pathogen-specific biomarkers for diagnosis of histoplasmosis

Authors: Juan David Puerta-Arias, Juan Pablo Isaza Agudelo, Tonny Williams Naranjo Preciado

Journal: Microbiol Spectr

PubMed ID: 37882565

Doi: 10.1128/spectrum.00939-23

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Evaluation and comparison of immune responses induced by two Mpox mRNA vaccine candidates in mice

Authors: Xidan Yang , Congxia Hu , Xuetao Yang , Xiu Yang , Xing Hu , Xingyun Wang , Cong Liu, Yuan Yuan , Shouwen Du , Peng George Wang, Jihui Lin

Journal: J Med Virol .

PubMed ID: 37800627

Doi: 10.1002/jmv.29140

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Horizontally transferred salivary protein promotes insect feeding by suppressing ferredoxin-mediated plant defenses

Authors: Yi-Zhe Wang , Yu-Xuan Ye , Jia-Bao Lu , Xin Wang , Hai-Bin Lu , Ze-Long Zhang , Zhuang-Xin Ye , Yu-Wen Lu , Zong-Tao Sun , Jian-Ping Chen , Jun-Min Li , Chuan-Xi Zhang , Hai-Jian Huang

Journal: Mol Biol Evol .

PubMed ID: 37804524

Doi: 10.1093/molbev/msad221

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Rapid characterization of anti-CRISPR proteins and optogenetically engineered variants using a versatile plasmid interference system

Authors: Guoxu Song, Chunhong Tian, Jiahui Li, Fei Zhang, Yuxin Peng, Xing Gao and Yong Tian

Journal: Nucleic Acids Research

Doi: 10.1093/nar/gkad995

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Establishment and characterization of a novel indirect ELISA method based on ASFV antigenic epitope-associated recombinant protein

Authors: Jiaxin Jin , Yilin Bai , Yuanyuan Zhang , Wenlong Lu , Shuai Zhang , Xuyang Zhao , Yaning Sun , Yanan Wu , Angke Zhang , Gaiping Zhang , Aijun Sun , Guoqing Zhuang

Journal: Int J Biol Macromol .

PubMed ID: 37865977

Doi: 10.1016/j.ijbiomac.2023.127311

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Endogenous Rab38 regulates LRRK2's membrane recruitment and substrate Rab phosphorylation in melanocytes

Authors: Alexandra Unapanta , Farbod Shavarebi , Jacob Porath , Yiyi Shen , Carson Balen , Albert Nguyen , Josh Tseng , Weng Si Leong , Michelle Liu , Pawel Lis , Santiago M Di Pietro , Annie Hiniker

Journal: J Biol Chem .

PubMed ID: 37625589

Doi: 10.1016/j.jbc.2023.105192

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A non-canonical role of endothelin converting enzyme 1 (ECE1) in promoting lung cancer development via directly targeting protein kinase B (AKT)

Authors: Li Chen, Yikai Lu, Mengmeng Zhao, Junfang Xu, Yan Wang, Qinghua Xu, Yajuan Cao, Haipeng Liu

Journal: J Gene Med

PubMed ID: 37897251

Doi: 10.1002/jgm.3612

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