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Recombinant T7 RNA polymerase production using ClearColi BL21(DE3) and animal-free media for in vitro transcription

Authors: Qianying Liang, Bowen Tu, Lun Cui

Journal: Appl Microbiol Biotechnol

PubMed ID: 38180552

Doi: 10.1007/s00253-023-12939-w

Products & Services: Molecular Biology Reagents

Astragaloside IV regulates circ_0001615 and miR-873-5p/LASP1 axis to suppress colorectal cancer cell progression

Authors: Pengfei Kong, Xuemei Tang, Fang Liu, Xuegui Tang

Journal: Chem Biol Drug Des

PubMed ID: 38230773

Doi: 10.1111/cbdd.14423

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Prevalence of IgG antibodies against Malawi polyomavirus in patients with autoimmune diseases and lymphoproliferative disorders subjected to bone marrow transplantation

Authors: Jérôme T J Nicol, Elisa Mazzoni, Maria Rosa Iaquinta, Raffaella De Pace, Pauline Gaboriaud, Natalia Maximova, Carolina Cason, Eleonora De Martino, Chiara Mazziotta, Pierre Coursaget, Antoine Touzé, Valentina Boz, Manola Comar, Mauro Tognon, Fernanda Martini

Journal: Front Immunol

PubMed ID: 38299147

Doi: 10.3389/fimmu.2023.1293313

Products & Services: Codon Optimization

Evolutionary preservation of CpG dinucleotides in RAG1 may elucidate the relatively high rate of methylation-mediated mutagenesis of RAG1 transposase

Authors: Mariam M Fawzy, Maiiada H Nazmy, Azza A K El-Sheikh, Moustafa Fathy

Journal: Immunol Res

PubMed ID: 38240953

Doi: 10.1007/s12026-023-09451-8

Products & Services: Molecular Biology Tools

Glycosylase-based base editors for efficient T-to-G and C-to-G editing in mammalian cells

Authors: Lijun Ye , Dongdong Zhao , Ju Li , Yiran Wang , Bo Li , Yuanzhao Yang , Xueting Hou , Huibin Wang , Zhandong Wei , Xiaoqi Liu , Yaqiu Li, Siwei Li , Yajing Liu , Xueli Zhang , Changhao Bi

Journal: Nat Biotechnol .

PubMed ID: 38168994

Doi: 10.1038/s41587-023-02050-w

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Cross-feeding promotes heterogeneity within yeast cell populations

Authors: Kevin K Y Hu, Ankita Suri, Geoff Dumsday, Victoria S Haritos

Journal: Nat Commun

PubMed ID: 38200012

Doi: 10.1038/s41467-023-44623-y

Products & Services: Codon Optimization

Cyclic di-GMP inhibits nitrate assimilation by impairing the antitermination function of NasT in Pseudomonas putida

Authors: Liang Nie, Yujie Xiao, Tiantian Zhou, Haoqi Feng, Meina He, Qingyuan Liang, Kexin Mu, Hailing Nie, Qiaoyun Huang, Wenli Chen

Journal: Nucleic Acids Res

PubMed ID: 38000372

Doi: 10.1093/nar/gkad1117

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Impact of surface receptors TLR2, CR3, and FcγRIII on Rhodococcus equi phagocytosis and intracellular survival in macrophages

Authors: Bibiana Petri da Silveira , Rola Barhoumi , Jocelyne M Bray , Hannah M Cole-Pfeiffer , Cory J Mabry , Robert C Burghardt , Noah D Cohen, Angela I Bordin

Journal: Immunity

PubMed ID: 38018994

Doi: 10.1128/iai.00383-23

Products & Services: Plasmid DNA Preparation

The HIV capsid mimics karyopherin engagement of FG-nucleoporins

Authors: C. F. Dickson, S. Hertel, A. J. Tuckwell, N. Li, J. Ruan, S. C. Al-Izzi, N. Ariotti, E. Sierecki, Y. Gambin, R. G. Morris, G. J. Towers, T. Böcking & D. A. Jacques

Journal: Nature

PubMed ID: 38267582

Doi: 10.1038/s41586-023-06969-7

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The cryo-EM structure of homotetrameric attachment glycoprotein from langya henipavirus

Authors: Yingying Guo , Songyue Wu , Wenting Li , Haonan Yang , Tianhao Shi , Bin Ju , Zheng Zhang , Renhong Yan

Journal: Nat Commun

PubMed ID: 38280880

Doi: 10.1038/s41467-024-45202-5

Products & Services: Recombinant Antibody Expression

Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

Authors: Eike-Christian Wamhoff , Larance Ronsard , Jared Feldman , Grant A Knappe , Blake M Hauser , Anna Romanov , James Brett Case , Shilpa Sanapala , Evan C Lam , Kerri J St Denis , Julie Boucau , Amy K Barczak , Alejandro B Balazs , Michael S Diamond , Aaron G Schmidt , Daniel Lingwood , Mark Bathe

Journal: Nat Commun

PubMed ID: 38291019

Doi: 10.1038/s41467-024-44869-0

Products & Services: PCR Cloning and Subcloning

Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy

Authors: Binh An Nguyen , Virender Singh , Shumaila Afrin , Anna Yakubovska , Lanie Wang , Yasmin Ahmed , Rose Pedretti , Maria Del Carmen Fernandez-Ramirez , Preeti Singh , Maja Pękała , Luis O Cabrera Hernandez , Siddharth Kumar , Andrew Lemoff , Roman Gonzalez-Prieto , Michael R Sawaya , David S Eisenberg , Merrill Douglas Benson , Lorena Saelices

Journal: Nat Commun

PubMed ID: 38233397

Doi: 10.1038/s41467-024-44820-3

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STYXL1 regulates CCT complex assembly and flagellar tubulin folding in sperm formation

Authors: Yu Chen , Mengjiao Luo , Haixia Tu , Yaling Qi , Yueshuai Guo , Xiangzheng Zhang , Yiqiang Cui , Mengmeng Gao , Xin Zhou , Tianyu Zhu , Hui Zhu , Chenghao Situ , Yan Li , Xuejiang Guo

Journal: Nat Commun

PubMed ID: 38168070

Doi: 10.1038/s41467-023-44337-1

Products & Services: Monoclonal Antibody Services

Cryo-EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH

Authors: Niraj Kumar , Shivani Sharma , Prem S Kaushal

Journal: Nat Commun

PubMed ID: 38245551

Doi: 10.1038/s41467-024-44879-y

Products & Services: Gene Synthesis

Biomimetic Control over Bimetallic Nanoparticle Structure and Activity via Peptide Capping Ligand Sequence

Authors: Maichong Xie, Ryuichi Shimogawa, Yang Liu, Lihua Zhang, Alexandre C. Foucher, Prahlad K. Routh, Eric A. Stach, Anatoly I. Frenkel*, and Marc R. Knecht

Journal: ACS Nano

PubMed ID: 38227802

Doi: 10.1021/acsnano.3c10016

Products & Services: Peptide Synthesis

Single-Molecule Analysis of SARS-CoV-2 Double-Stranded Polynucleotides Using Solid-State Nanopore with AI-Assisted Detection and Classification: Implications for Understanding Disease Severity

Authors: Ibrar Alam, Thitikorn Boonkoom, Harit Pitakjakpipop, Poramin Boonbanjong, Kawin Loha, Thanaya Saeyang, Jarunee Vanichtanankul, Deanpen Japrung

Journal: ACS Appl Bio Mater

PubMed ID: 38194666

Doi: 10.1021/acsabm.3c00998

Products & Services: PCR Cloning and Subcloning

A general platform for targeting MHC-II antigens via a single loop

Authors: Haotian Du, Jingjia Liu, Kevin M Jude, Xinbo Yang, Ying Li, Braxton Bell, Hongli Yang, Audrey Kassardjian, Ali Mobedi, Udit Parekh, R Andres Parra Sperberg, Jean-Philippe Julien, Elizabeth D Mellins, K Christopher Garcia, Po-Ssu Huang

Journal: biorxiv

PubMed ID: 38352315

Doi: 10.1101/2024.01.26.577489

Products & Services: Molecular Biology Reagents

PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease

Authors: Guangyu Zhou, Chen Zhang, Hui Peng, Xuesong Su, Qun Huang, Zixia Zhao, Guangyi Zhao

Journal: Mol Med

PubMed ID: 38200452

Doi: 10.1186/s10020-023-00759-7

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Structural insights into the activation and inhibition of CXC chemokine receptor 3

Authors: Haizhan Jiao, Bin Pang, Aijun Liu, Qiang Chen, Qi Pan, Xiankun Wang, Yunong Xu, Ying-Chih Chiang, Ruobing Ren, Hongli Hu

Journal: Nat Struct Mol Biol

PubMed ID: 38177682

Doi: 10.1038/s41594-023-01175-5

Products & Services: Proteins, Expression, Isolation and Analysis

Structural biases in disordered proteins are prevalent in the cell

Authors: David Moses, Karina Guadalupe, Feng Yu, Eduardo Flores, Anthony R Perez, Ralph McAnelly, Nora M Shamoon, Gagandeep Kaur, Estefania Cuevas-Zepeda, Andrea D Merg, Erik W Martin, Alex S Holehouse, Shahar Sukenik

Journal: Nat Struct Mol Biol

PubMed ID: 38177684

Doi: 10.1038/s41594-023-01148-8

Products & Services: Gene Synthesis

Response to COVID-19 vaccination in patients on cancer therapy: Analysis in a SARS-CoV-2-naïve population

Authors: George Cavic, Andrew A Almonte, Sarah M Hicks, Teresa Neeman, Jo-Wai Wang, Sue Brew, Philip Y Choi, Ian Cockburn, Elizabeth E Gardiner, Desmond Yip, Aude M Fahrer, Yada Kanjanapan

Journal: Asia Pac J Clin Oncol

PubMed ID: 38221764

Doi: 10.1111/ajco.14047

Products & Services: Recombinant Proteins

PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial

Authors: Francisco J Martinez, Michael White, Micheline Guillotte-Blisnick, Christèle Huon, Alix Boucharlat, Fabrice Agou, Patrick England, Jean Popovici, Mimi M Hou, Sarah E Silk, Jordan R Barrett, Carolyn M Nielsen, Jenny M Reimer, Paushali Mukherjee, Virander S Chauhan, Angela M Minassian, Simon J Draper, Chetan E Chitnis

Journal: npj Vaccines

PubMed ID: 38184681

Doi: 10.1038/s41541-023-00796-7

Products & Services: Molecular Biology Reagents

Comparative Study on the Immunogenicity of COVID-19 mRNA Vaccines in Patients Receiving Adjuvant and Palliative Chemotherapy

Authors: Hyun-Woo Choi, Younggon Jung, Uh Jin Kim, Sang-Cheol Lee, Jung Hye Kwon, Hyeonjong Kim, Sarah Kim, Yoonjung Lee, Hyun-Jung Shim, Sang-Hee Cho, Ik-Joo Chung, Eu Chang Hwang, Seung Ji Kang, Woo Kyun Bae, Seung-Jung Kee

Journal: Chonnam Med J

PubMed ID: 38304127

Doi: 10.4068/cmj.2024.60.1.69

Products & Services: Molecular Biology Reagents

Up-regulation of lncRNA WT1-AS ameliorates Aβ-stimulated neuronal injury through modulation of miR-186-5p/CCND2 axis in Alzheimer's disease

Authors: Yun Tang, Xiaojiu Zhang, Shihui Wang, Lu Liu, Qing Wang, Yufeng Liu, Yadong Yu, Qijin Zhai

Journal: Cell Mol Biol (Noisy-le-grand)

PubMed ID: 38372094

Doi: 10.14715/cmb/2024.70.1.27

Products & Services: Molecular Biology Reagents

Spatial and Single-Cell Transcriptomics Reveal a Cancer-Associated Fibroblast Subset in HNSCC That Restricts Infiltration and Antitumor Activity of CD8+ T Cells

Authors: Chuwen Li, Haiyan Guo, Peisong Zhai, Ming Yan, Chun Liu, Xiaoning Wang, Chaoji Shi, Jiang Li, Tong Tong, Zhiyuan Zhang, Hailong Ma, Jianjun Zhang

Journal: Cancer Res

PubMed ID: 37930937

Doi: 10.1158/0008-5472.CAN-23-1448

Products & Services: Proteins, Expression, Isolation and Analysis

Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake

Authors: Kazuki Takeda, Taki Saito, Sakura Sasaki, Akifumi Eguchi, Makoto Sugiyama, Saeka Eto, Kio Suzuki, Ryo Kamata

Journal: Toxics

PubMed ID: 38251008

Doi: 10.3390/toxics12010052

Products & Services: DNA Sequencing

Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia

Authors: Wenhua Jiang, Qiangqiang Hou, Hongrui Xu, Kexin Yang, Xiaohui Wang, Kuojun Zhang, Yi Zeng, Wenqiang Li, Bingrui Wang, Guangmei Luo, Xiaofan Zhao, Hui Shen, Yong Xu, Xiaoxing Wu

Journal: J Med Chem

PubMed ID: 38175809

Doi: 10.1021/acs.jmedchem.3c02104

Products & Services: Proteins, Expression, Isolation and Analysis

Local Multiple-site Injections of a Plasmid Encoding Human Mitigate Radiation-induced Skin Injury by Inhibiting Ferroptosis

Authors: Xiaoying Wang, Yuxin Lu, Xiaochen Cheng, Xuefeng Zhu, Dujuan Li, Haiying Duan, Shenhui Hu, Fengjun Xiao, Li Du, Qinglin Zhang

Journal: Curr Drug Deliv

PubMed ID: 37157191

Doi: 10.2174/1567201820666230508120720

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Bioactive Polyurethane-Poly(ethylene Glycol) Diacrylate Hydrogels for Applications in Tissue Engineering

Authors: Yixuan Yuan, Caleb Tyson, Annika Szyniec, Samuel Agro, Tara N Tavakol, Alexander Harmon, DessaRae Lampkins, Lauran Pearson, Jerald E Dumas, Lakeshia J Taite

Journal: Gels

PubMed ID: 38391438

Doi: 10.3390/gels10020108

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Enhanced immunogenicity and protective efficacy in mice following a Zika DNA vaccine designed by modulation of membrane-anchoring regions and its association to adjuvants

Authors: Franciane Mouradian Emidio Teixeira, Luana de Mendonça Oliveira, Anna Cláudia Calvielli Castelo Branco, Ricardo Wesley Alberca, Emanuella Sarmento Alho de Sousa, Bruno Henrique de Sousa Leite, Wenny Camilla Dos Santos Adan, Alberto José da Silva Duarte, Roberto Dias Lins, Maria Notomi Sato, Isabelle Freire Tabosa Viana

Journal: Front Immunol

PubMed ID: 38361945

Doi: 10.3389/fimmu.2024.1307546

Products & Services: Molecular Biology Reagents

Inter-alpha-trypsin inhibitor (IαI) and hyaluronan modifications enhance the innate immune response to influenza virus in the lung

Authors: Fengying Tang, Stephen R Reeves, Jourdan E Brune, Mary Y Chang, Christina K Chan, Peter Waldron, Sheona P Drummond, Caroline M Milner, Kimberly M Alonge, Stavros Garantziotis, Anthony J Day, William A Altemeier, Charles W Frevert

Journal: Matrix Biol

PubMed ID: 38232913

Doi: 10.1016/j.matbio.2024.01.004

Products & Services: Proteins, Expression, Isolation and Analysis

In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy

Authors: Brandon Lam, Yu Jui Kung, John Lin, Ssu-Hsueh Tseng, Hsin-Fang Tu, Claire Huang, Brandon Lee, Esteban Velarde, Ya Chea Tsai, Rafael Villasmil, Sung Taek Park, Deyin Xing, Chien-Fu Hung, T-C Wu

Journal: J Clin Invest

PubMed ID: 37917174

Doi: 10.1172/JCI171621

Products & Services: PCR Cloning and Subcloning

The naringenin-dependent regulator FdeR can be applied as a NIMPLY gate controlled by naringenin and arabinose

Authors: Fernanda Miyuki Kashiwagi, Brenno Wendler Miranda, Emanuel Maltempi de Souza, Marcelo Müller-Santos

Journal: Synth Biol (Oxf)

PubMed ID: 38249314

Doi: 10.1093/synbio/ysae001

Products & Services: Gene Synthesis

A Novel Role for the Adenovirus L4 Region 22K and 33K Proteins in Adeno-Associated Virus Production

Authors: Angela Adsero, Brendan Chestnut, Sara Shahnejat-Bushehri, Lalita Sasnoor, Travis McMurphy, Mike Swenor, Ryan Pasquino, Arun Pradhan, Victor Hernandez, Linas Padegimas, David Dismuke

Journal: Hum Gene Ther

PubMed ID: 38062776

Doi: 10.1089/hum.2023.146

Products & Services: Recombinant Proteins

Cascaded amplifying circuit enables sensitive detection of fungal pathogens

Authors: Cong Fan, Nike He, Jifeng Yuan

Journal: Biosens Bioelectron

PubMed ID: 38281368

Doi: 10.1016/j.bios.2024.116058

Products & Services: Gene Synthesis

An inducible CRISPRi circuit for tunable dynamic regulation of gene expression in Saccharopolyspora erythraea

Authors: Xing Jiang, Xiang Ke, Xiwei Tian, Ju Chu

Journal: Biotechnol Lett

PubMed ID: 38279045

Doi: 10.1007/s10529-023-03462-z

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Estimation of the Parasitic Burden of Soil-Transmitted Helminths Among Pregnant Women in the Maharashtra State of India Using qPCR: A Community-Based Study

Authors: Shilpa Gaidhane, Abhay Gaidhane, Mahalaqua Nazli Khatib, Shital Telrandhe, Manoj Patil, Deepak Saxena, Pankaj Bhardwaj, Sonali Choudhari, Quazi S Zahiruddin

Journal: Indian J Community Med

PubMed ID: 38425985

Doi: 10.4103/ijcm.ijcm_249_23

Products & Services: PCR Cloning and Subcloning

KDM6A Demethylase Regulates Renal Sodium Excretion and Blood Pressure

Authors: Xiaobin Han, Leah Akinseye, Zhongjie Sun

Journal: Hypertension

PubMed ID: 38164755

Doi: 10.1161/HYPERTENSIONAHA.123.22026

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from

Authors: Fredrik Leo, Rolf Lood, Kristina A Thomsson, Jonas Nilsson, Gunnel Svensäter, Claes Wickström

Journal: Front Microbiol

PubMed ID: 38304711

Doi: 10.3389/fmicb.2024.1340109

Products & Services: Molecular Biology Reagents

Functionally coherent transcriptional responses of Jatropha curcas and Pseudomonas fragi for rhizosphere mediated degradation of pyrene

Authors: L Paikhomba Singha, K Malabika Singha, Piyush Pandey

Journal: Sci Rep

PubMed ID: 38200308

Doi: 10.1038/s41598-024-51581-y

Products & Services: PCR Cloning and Subcloning

A Mixture of T-Cell Epitope Peptides Derived from Human Respiratory Syncytial Virus F Protein Conferred Protection in DR1-TCR Tg Mice

Authors: Hong Guo, Yang Song, Hai Li, Hongqiao Hu, Yuqing Shi, Jie Jiang, Jinyuan Guo, Lei Cao, Naiying Mao, Yan Zhang

Journal: Vaccines (Basel)

PubMed ID: 38250890

Doi: 10.3390/vaccines12010077

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Safety, Immunogenicity, and Mechanism of a Rotavirus mRNA-LNP Vaccine in Mice

Authors: Chenxing Lu, Yan Li, Rong Chen, Xiaoqing Hu, Qingmei Leng, Xiaopeng Song, Xiaochen Lin, Jun Ye, Jinlan Wang, Jinmei Li, Lida Yao, Xianqiong Tang, Xiangjun Kuang, Guangming Zhang, Maosheng Sun, Yan Zhou, Hongjun Li

Journal: Viruses

PubMed ID: 38399987

Doi: 10.3390/v16020211

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Efficient treatment of colon cancer with codelivery of TRAIL and imatinib by liposomes

Authors: Rongrong Fu, Rui Chang, Andong Peng, Changshun Feng, Weifan Zhu, Yi Chen, Xue Tian, Rui Wang, Hui Yan, Dianlong Jia, Jun Li

Journal: Pharm Dev Technol

PubMed ID: 38230653

Doi: 10.1080/10837450.2024.2301763

Products & Services: Proteins, Expression, Isolation and Analysis

Host protein EPCAM interacting with EtMIC8-EGF is essential for attachment and invasion of Eimeria tenella in chickens

Authors: Lingyu Sun, Chao Li, Ningning Zhao, Bingxiang Wang, Hongmei Li, Hairong Wang, Xiao Zhang, Xiaomin Zhao