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LLPS REDIFINE allows the biophysical characterization of multicomponent condensates without tags or labels

Authors: Mihajlo Novakovic, Yaning Han, Nina C Kathe, Yinan Ni, Leonidas Emmanouilidis, Frédéric H-T Allain

Journal: Nature Communications

PubMed ID: 40389460

Doi: 10.1038/s41467-025-59759-2

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Human mitochondrial ferritin exhibits highly unusual iron-O2 chemistry distinct from that of cytosolic ferritins

Authors: Justin M Bradley , Zinnia Bugg , Jacob Pullin , Geoffrey R Moore, Dimitri A Svistunenko , Nick E Le Brun

Journal: Nature Communications

PubMed ID: 40393986

Doi: 10.1038/s41467-025-59463-1

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Cell trajectory modulation: rapid microfluidic biophysical profiling of CAR T cell functional phenotypes

Authors: Kerwin Kwek Zeming, Kai Yun Quek, Wei-Xiang Sin, Denise Bei Lin Teo, Ka-Wai Cheung, Chin Ren Goh, Faris Kairi, Elizabeth Lee, Francesca Lorraine Wei Inng Lim, Michaela Su-Fern Seng, Shui Yen Soh, Michael E Birnbaum, Jongyoon Han

Journal: Nature Communications

PubMed ID: 40404664

Doi: 10.1038/s41467-025-59789-w

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FOXA2 promotes metastatic competence in small cell lung cancer

Authors: Kenta Kawasaki, Sohrab Salehi, Yingqian A Zhan, Kevin Chen, Jun Ho Lee, Eralda Salataj, Hong Zhong, Parvathy Manoj, Dennis Kinyua, Barbara P Mello, Harsha Sridhar, Sam E Tischfield, Irina Linkov, Nicholas Ceglia, Matthew Zatzman, Eliyahu Havasov, Neil J Shah, Fanli Meng, Brian Loomis, Umesh K Bhanot, Esther Redin, Elisa de Stanchina, Pierre-Jacques Hamard, Richard P Koche, Andrew McPherson, Álvaro Quintanal-Villalonga, Sohrab P Shah, Joan Massagué, Charles M Rudin

Journal: Nature Communications

PubMed ID: 40419484

Doi: 10.1038/s41467-025-60141-5

Deletion of the Envelope gene attenuates SARS-CoV-2 infection by altered Spike localization and increased cell-to-cell transmission

Authors: Hannah L. Fischer; Christopher Kline; W. Paul Duprex; Kevin R. McCarthy; Simon C. Watkins; James F. Conway; Zandrea Ambrose

Journal: biorxiv

PubMed ID: 40475451

Doi: 10.1101/2025.05.20.655126

A yeast-based system to study SARS-CoV-2 M pro structure and to identify nirmatrelvir resistant mutations

Authors: Jin Ou; Eric M. Lewandowski; Yanmei Hu; Austin A. Lipinski; Ryan T. Morgan; Lian M.C. Jacobs; Xiujun Zhang; Melissa J. Bikowitz; Paul Langlais; Haozhou Tan; Jun Wang; Yu Chen; John S. Choy

Journal: research square

PubMed ID: 36052369

Doi: 10.21203/rs.3.rs-1942964/v1

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A yeast-based system to study SARS-CoV-2 M pro structure and to identify nirmatrelvir resistant mutations

Authors: Jin Ou; Eric M. Lewandowski; Yanmei Hu; Austin A. Lipinski; Ryan T. Morgan; Lian M.C. Jacobs; Xiujun Zhang; Melissa J. Bikowitz; Paul Langlais; Haozhou Tan; Jun Wang; Yu Chen; John S. Choy

Journal: research square

PubMed ID: 36052369

Doi: 10.21203/rs.3.rs-1942964/v1

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A fluorescence-based assay for measuring polyamine biosynthesis aminopropyl transferase mediated catalysis

Authors: Pallavi Singh; Jae-Yeon Choi; Weiwei Wang; Tukiet T. Lam; Philip Lechner; Christopher D. Vanderwal; Sovitj Pou; Aaron Nilsen; Choukri Ben Mamoun

Journal: The Journal of Biological Chemistry

PubMed ID: 39342998

Doi: 10.1016/j.jbc.2024.107832

Discovery of benzethonium chloride as a potent STAT3 inhibitor for the treatment of HNSCC

Authors: Yuefeng Han; Shumin Li; Deshang Chen; Mingjie Zhang; Guoying Han; QianQian Xu; Xianming Ge; Mengli Wang; Yan Pan; Sien Ma; Beibei Xu; Mengmeng Deng; Bao Zhao

Journal: Frontiers in pharmacology

PubMed ID: 40242440

Doi: 10.3389/fphar.2025.1569570

Products & Services: Protein and Antibody Isolation

Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors

Authors: Xujie Zhang; Lin Sun; Megan E. Meuser; Waleed A. Zalloum; Shujing Xu; Tianguang Huang; Srinivasulu Cherukupalli; Xiangyi Jiang; Xiao Ding; Yucen Tao; Dongwei Kang; Erik De Clercq; Christophe Pannecouque; Alexej Dick; Simon Cocklin; Xinyong Liu; Peng Zhan

Journal: European Journal of Medicinal Chemistry

PubMed ID: 34592608

Doi: 10.1016/j.ejmech.2021.113848

Products & Services: Peptide Synthesis

Influence of expression and purification protocols on G biochemical activity: kinetics of plant and mammalian G protein cycles

Authors: Timothy E. Gookin; David Chakravorty; Sarah M. Assmann

Journal: Frontiers in molecular biosciences

PubMed ID: 40260404

Doi: 10.3389/fmolb.2025.1513660

Products & Services: Gene Synthesis

Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori

Authors: Md. Nahian; Md. Rasel Khan; Fabiha Rahman; Hossain Mohammed Reza; Imren Bayil; Tanjum Ahmed Nodee; Tabassum Basher; Mostafizur Rahaman Sany; Rabeya Najnin Munmun; S. M. Ariful Habib; Lincon Mazumder; Mrityunjoy Acharjee; Abu Tayab Moin; Abu Tayab Moin; Abu Tayab Moin

Journal: PLoS ONE

PubMed ID: 39919064

Doi: 10.1371/journal.pone.0318750

De Novo Multi Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Authors: Xiaojuan Li; Haifan Gong; Yue Wang; Yinuo Zhao; Lixiang Li; Peijing Bao; Qingzhou Kong; Jialu Fu; Boyao Wan; Yumeng Zhang; Jinghui Zhang; Jiekun Ni; Zhongxue Han; Xueping Nan; Kunping Ju; Longfei Sun; Yuerui Ma; Huijun Chang; Mengqi Zheng; Yanbo Yu; Xiaoyun Yang; Xiuli Zuo; Haina Wang; Yanqing Li

Journal: Advanced Science

PubMed ID: 41801219

Doi: 10.1002/advs.202515835

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SIRT2-mediated deacetylation of LCK governs the magnitude of T cell receptor signaling

Authors: Imene Hamaidi; Pingyan Cheng; Soo Young Jun; Alak Manna; Min-Hsuan Wang; Anh Nguyen; Ismail Can; Min G. Zhang; Odesha O. Taylor; Luis Uriel Lopez Bailon; Bin Fang; Bradford Perez; Ben C. Creelan; Andriy Marusyk; Dongjun Shin; Tae Hyun Hwang; Anders E. Berglund; Virginia S. Shapiro; Haitao M. Ji; Jos R. Conejo-Garcia; Sungjune Kim

Journal: nature immunology

PubMed ID: 41611868

Doi: 10.1038/s41590-025-02377-3

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Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay

Authors: Chunlong Ma; Michael Dominic Sacco; Zilei Xia; George Lambrinidis; Julia Alma Townsend; Yanmei Hu; Xiangzhi Meng; Tommy Szeto; Mandy Ba; Xiujun Zhang; Maura Gongora; Fushun Zhang; Michael Thomas Marty; Yan Xiang; Antonios Kolocouris; Yu Chen; Jun Wang

Journal: ACS central science

PubMed ID: 34341772

Doi: 10.1021/acscentsci.1c00519

Stabilization mechanism accommodating genome length variation in evolutionarily related viral capsids

Authors: Jennifer M. Podgorski, Joshua Podgorski, Lawrence Abad, Deborah Jacobs-Sera, Krista G. Freeman, Colin Brown, Graham F. Hatfull, Antoni Luque & Simon J. White

Journal: Nature Communications

PubMed ID: 40175362

Doi: 10.1038/s41467-025-58298-0

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Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment

Authors: Zhuoyao Chen, Gamma Chi, Timea Balo, Xiangrong Chen, Beatriz Ralsi Montes, Steven C. Clifford, Vincenzo D’Angiolella, Timea Szabo, Arpad Kiss, Tibor Novak, András Herner, András Kotschy & Alex N. Bullock

Journal: Nature Communications

PubMed ID: 40175372

Doi: 10.1038/s41467-025-58350-z

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Enhanced the Trans-Cleavage Activity of CRISPR-Cas12a Using Metal-Organic Frameworks as Stimulants for Efficient Electrochemical Sensing of Circulating Tumor DNA

Authors: Shuai Wu, Yincheng Liu, Tianyu Zeng, Tianci Zhou, Yanting Sun, Ying Deng, Juan Zhang, Genxi Li, Yongmei Yin

Journal: Advanced Science

PubMed ID: 40184611

Doi: 10.1002/advs.202417206

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CD22 TCR-engineered T cells exert antileukemia cytotoxicity without causing inflammatory responses

Authors: Kilyna A Nguyen, Zhihui Liu, John S Davies, Crystal P McIntosh, Lindsey M Draper, Scott M Norberg, Zachary Rae, Sooraj R Achar, Gregoire Altan-Bonnet, Ling Zhang, Xiaolin Wu, Thomas J Meyer, Michael C Kelly, Naomi Taylor, Christian S Hinrichs, Kazusa Ishii

Journal: SCIENCE ADVANCES

PubMed ID: 40203088

Doi: 10.1126/sciadv.adq4297

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Engineered depalmitoylases enable selective manipulation of protein localization and function

Authors: Srinidhi Jayaraman, Audrey Kochiss, Thy-Lan Alcalay, Pedro J. del Rivero Morfin & Manu Ben-Johny

Journal: Nature Communications

PubMed ID: 40223127

Doi: 10.1038/s41467-025-58908-x

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Chromosome end protection by RAP1-mediated inhibition of DNA-PK

Authors: Patrik Eickhoff, Ceylan Sonmez, Charlotte E. L. Fisher, Oviya Inian, Theodoros I. Roumeliotis, Angela dello Stritto, Jörg Mansfeld, Jyoti S. Choudhary, Sebastian Guettler, Francisca Lottersberger & Max E. Douglas

Journal: Nature

PubMed ID: 40240611

Doi: 10.1038/s41586-025-08896-1

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Hydrogels with programmed spatiotemporal mechanical cues for stem cell-assisted bone regeneration

Authors: Bin Xue, Zhengyu Xu, Lan Li, Kaiqiang Guo, Jing Mi, Haipeng Wu, Yiran Li, Chunmei Xie, Jing Jin, Juan Xu, Chunping Jiang, Xiaosong Gu, Meng Qin, Qing Jiang, Yi Cao & Wei Wang

Journal: Nature Communications

PubMed ID: 40240370

Doi: 10.1038/s41467-025-59016-6

Mechanism of small heat shock protein client sequestration and induced polydispersity

Authors: Adam P. Miller & Steve L. Reichow

Journal: Nature Communications

PubMed ID: 40240363

Doi: 10.1038/s41467-025-58964-3

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SNAP25-dependent membrane trafficking of the Kv1.5 channel regulates the onset of atrial fibrillation

Authors: Xuling Su, Beihua Shao, Zhiwen Chen, Hongcheng Gu, Ke Xiong, Guanghua Wang, Qicheng Zou, Yuting Cao, Caihong Zhang, Hongtao Xu, Yixin Yuan, Xuxia Zhao, Yi Liu, Yunli Shen, Duanyang Xie, Yi-Han Chen

Journal: Nature Communications

PubMed ID: 40253375

Doi: 10.1038/s41467-025-59096-4

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Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias

Authors: Won Jun Kim, Edie I Crosse, Emma De Neef, Inaki Etxeberria, Erich Y Sabio, Eric Wang, Jan Philipp Bewersdorf, Kuan-Ting Lin, Sydney X Lu, Andrea Belleville, Nina Fox, Cynthia Castro, Pu Zhang, Takeshi Fujino, Jennifer Lewis, Jahan Rahman, Beatrice Zhang, Jacob H Winick, Alexander M Lewis, Robert F Stanley, Susan DeWolf, Brigita Meškauskaitė Urben, Meril Takizawa, Tobias Krause, Henrik Molina, Ronan Chaligne, Priya Koppikar, Jeffrey Molldrem, Mathieu Gigoux, Taha Merghoub, Anthony Daniyan, Smita S Chandran, Benjamin D Greenbaum, Christopher A Klebanoff, Robert K Bradley, Omar Abdel-Wahab

Journal: Cell

PubMed ID: 40273911

Doi: 10.1016/j.cell.2025.03.047

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Teleost GSDMEc regulates GSDMEa-mediated pyroptos

Authors: Hang Xu, Meng Wu, Yujian Wang, Yaoming Jiao, Yuan Chen, Zihao Yuan, Li Sun

Journal: J Adv Res

PubMed ID: 40210150

Doi: doi.org/10.1016/j.jare.2025.04.007

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The ribosome-associated quality control factor TCF25 imposes K48 specificity on Listerin-mediated ubiquitination of nascent chains by binding and specifically orienting the acceptor ubiquitin

Authors: Irina S Abaeva, Alexander G Bulakhov, Christopher U T Hellen, Tatyana V Pestova

Journal: Genes Dev

PubMed ID: 40169231

Doi: 10.1101/gad.352389.124

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BARD1-mediated stabilization of METTL14 promotes retinal neovascularization by m6A-modifying MXD1 mRNA on a YTHDF2-dependent manner

Authors: Xianyang Liu, Shuhao Zeng, Jiayu Meng, Qian Zhou, Fan Cao, Baorui Chu, Chao Wu, Yakun Wang, Hui Feng, Xiaorui Bi, Xinyuan Chen, Wenxian Yang, Meng Tian, Hui Yang, Ke Hu, Shengping Hou

Journal: Theranostics

Doi: 10.7150/thno.110122

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Development of a highly sensitive C1QC-targeting aptamer and its application in a modified antibody-aptamer sandwich biosensor for C1QC biomarker detection

Authors: Wenwei Wu, Lixia Qian, Jie Shen, Hongmei Li, Liang-cheng Li

Journal: Sensors and Actuators: B. Chemical

Doi: doi.org/10.1016/j.snb.2025.137828

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Developmentally endothelial locus-1 facilitates intestinal inflammation resolution by suppressing the Cmpk2-cGAS-STING pathway and promoting reparatory macrophage transition

Authors: Meihui Tao, Li Wang, Chaoyue Chen, Mengfan Tang, Yanping Wang, Jingyue Zhang, Xi Zhao, Qinyu Feng, Junfa Chen, Wei Yan, Rong Lin, Yu Fu

Journal: Journal of Advanced Research

PubMed ID: 40288675

Doi: 10.1016/j.jare.2025.04.030

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An evolutionarily unique viral RdRP suggests a common dual-function feature of the priming element

Authors: Hengxia Jia, Shunli Liu, Guibo Rao, Qiaojie Liu, Jiqin Wu, Sheng Cao, Peng Gong

Journal: Sci Adv

PubMed ID: 40249801

Doi: 10.1126/sciadv.adv9640

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Fused exosomal targeted therapy in periprosthetic osteolysis through regulation of bone metabolic homeostasis

Authors: Tianliang Ma, Qimeng Liu, Zheyu Zhang, Jiangyu Nan, Guanzhi Liu, Yute Yang, Yihe Hu, Jie Xie

Journal: Bioactive Materials

PubMed ID: 40248188

Doi: doi.org/10.1016/j.bioactmat.2025.04.006

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Identification of RC3H1 as antiviral host factor binding to the non-structural protein 1 of Influenza A virus via a 3-stage computational pipeline and cell-based analysis

Authors: Swee Teng Teo , Shamima Rashid , Kong Yen Liew , Kah Man Lai , Teng Ann Ng , Jifeng Jiao , Chee Keong Kwoh , Yee-Joo Tan

Journal: Virology Journal

PubMed ID: 40287742

Doi: 10.1186/s12985-025-02746-2

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Virus glycoprotein nanodisc platform for vaccine design

Authors: Kimmo Rantalainen; Alessia Liguori; Gabriel Ozorowski; Claudia Flynn; Jon M. Steichen; Olivia Swanson; Patrick J. Madden; Sabyasachi Baboo; Swastik Phulera; Anant Gharpure; Danny Lu; Oleksandr Kalyuzhniy; Patrick Skog; Sierra Terada; Monolina Shil; Jolene K. Diedrich; Erik Georgeson; Ryan Tingle; Saman Eskandarzadeh; Wen-Hsin Lee; Nushin Alavi; Diana Goodwin; Michael Kubitz; Sonya Amirzehni; Sunny Himansu; Devin Sok; Jeong Hyun Lee; John R. Yates; James C. Paulson; Shane Crotty; Torben Schiffner; Andrew B. Ward; William R. Schief

Journal: biorxiv

PubMed ID: 40666859

Doi: 10.1101/2025.05.02.651272

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S-ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide-Induced Depression Via Targeting SIRT2

Authors: Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang

Journal: Advanced Science

PubMed ID: 40171943

Doi: 10.1002/advs.202416481

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A predatory gene drive for targeted control of self-transmissible plasmids

Authors: Ryan Tsoi, Hye-In Son, Grayson S Hamrick, Katherine Tang, Jonathan H Bethke, Jia Lu, Rohan Maddamsetti, Lingchong You

Journal: SCIENCE ADVANCES

PubMed ID: 40173243

Doi: 10.1126/sciadv.ads4735

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Supra-second tracking and live-cell karyotyping reveal principles of mitotic chromosome dynamics

Authors: Rumen Stamatov, Sonya Uzunova, Yoana Kicheva, Maria Karaboeva, Tavian Blagoev, Stoyno Stoynov

Journal: Nature Cell Biology

PubMed ID: 40185948

Doi: 10.1038/s41556-025-01637-6

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Engineered nucleocytosolic vehicles for loading of programmable editors

Authors: Julian Geilenkeuser, Niklas Armbrust, Emily Steinmaßl, Samuel W Du, Sebastian Schmidt, Eva Maria Hildegard Binder, Yuchun Li, Niklas Wilhelm Warsing, Stephanie Victoria Wendel, Florian von der Linde, Elisa Marie Schiele, Xiya Niu, Luisa Stroppel, Oleksandr Berezin, Tobias Heinrich Santl, Tanja Orschmann, Keith Nelson, Christoph Gruber, Grazyna Palczewska, Carolline Rodrigues Menezes, Eleonora Risaliti, Zachary J Engfer, Naile Koleci, Andrea Schmidts, Arie Geerlof, Krzysztof Palczewski, Gil Gregor Westmeyer, Dong-Jiunn Jeffery Truong

Journal: Cell

PubMed ID: 40209705

Doi: 10.1016/j.cell.2025.03.015

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The bridge-like lipid transport protein VPS13C/PARK23 mediates ER-lysosome contacts following lysosome damage

Authors: Xinbo Wang, Peng Xu, Amanda Bentley-DeSousa, William Hancock-Cerutti, Shujun Cai, Benjamin T. Johnson, Francesca Tonelli, Lin Shao, Gabriel Talaia, Dario R. Alessi, Shawn M. Ferguson & Pietro De Camilli

Journal: Nature Cell Biology

PubMed ID: 40211074

Doi: 10.1038/s41556-025-01653-6

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Nanoparticle delivery of a prodrug-activating bacterial enzyme leads to anti-tumor responses

Authors: Sebastian G. Huayamares, Liming Lian, Regina Rab, Yuning Hou, Afsane Radmand, Hyejin Kim, Ryan Zenhausern, Bhagelu R. Achyut, Melissa Gilbert Ross, Melissa P. Lokugamage, David Loughrey, Hannah E. Peck, Elisa Schrader Echeverri, Alejandro J. Da Silva Sanchez, Aram Shajii, Andrea Li, Karen E. Tiegreen, Philip J. Santangelo, Eric J. Sorscher & James E. Dahlman

Journal: Nature Communications

PubMed ID: 40221395

Doi: 10.1038/s41467-025-58548-1

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Fibromodulin selectively accelerates myofibroblast apoptosis in cutaneous wounds by enhancing interleukin 1β signaling

Authors: Wenlu Jiang, Xiaoxiao Pang, Pin Ha, Chenshuang Li, Grace Xinlian Chang, Yuxin Zhang, Lawrence A. Bossong, Kang Ting, Chia Soo & Zhong Zheng

Journal: Nature Communications

PubMed ID: 40221432

Doi: 10.1038/s41467-025-58906-z

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Vesicular and non-vesicular extracellular small RNAs direct gene silencing in a plant-interacting bacterium

Authors: Antinéa Ravet, Jérôme Zervudacki, Meenu Singla-Rastogi, Magali Charvin, Odon Thiebeauld, Alvaro L. Perez-Quintero, Lucas Courgeon, Adrien Candat, Liam Lebeau, Antonio Emidio Fortunato, Venugopal Mendu & Lionel Navarro

Journal: Nature Communications

PubMed ID: 40229238

Doi: 10.1038/s41467-025-57908-1

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Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines

Authors: Paweł S Krawczyk, Michał Mazur, Wiktoria Orzeł, Olga Gewartowska, Sebastian Jeleń, Wiktor Antczak, Karolina Kasztelan, Aleksandra Brouze, Katarzyna Matylla-Kulińska, Natalia Gumińska, Bartosz Tarkowski, Ewelina P Owczarek, Kamila Affek, Paweł Turowski, Agnieszka Tudek, Małgorzata Sroka, Tomasz Śpiewla, Monika Kusio-Kobiałka, Aleksandra Wesołowska, Dominika Nowis, Jakub Golab, Joanna Kowalska, Jacek Jemielity, Andrzej Dziembowski, Seweryn Mroczek

Journal: Nature

PubMed ID: 40240603

Doi: 10.1038/s41586-025-08842-1

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Josephin Domain Containing 2 (JOSD2) inhibition as Pan-KRAS-mutation-targeting strategy for colorectal cancer

Authors: Tao Yuan, Yue Liu, Ruilin Wu, Meijia Qian, Weihua Wang, Yonghao Li, Hongdao Zhu, Jia’er Wang, Fujing Ge, Chenming Zeng, Xiaoyang Dai, Ronggui Hu, Tianhua Zhou, Qiaojun He, Hong Zhu & Bo Yang

Journal: Nature Communications

PubMed ID: 40240366

Doi: 10.1038/s41467-025-58923-y

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BMAL1–HIF2A heterodimer modulates circadian variations of myocardial injury

Authors: Wei Ruan, Tao Li, In Hyuk Bang, Jaewoong Lee, Wankun Deng, Xinxin Ma, Cong Luo, Fang Du, Seung-Hee Yoo, Boyun Kim, Jiwen Li, Xiaoyi Yuan, Katherine Figarella, Yu A. An, Yin-Ying Wang, Yafen Liang, Matthew DeBerge, Dongze Zhang, Zhen Zhou, Yanyu Wang, Joshua M. Gorham, Jonathan G. Seidman, Christine E. Seidman, Sary F. Aranki, …Holger K. Eltzschig

Journal: Nature

PubMed ID: 40269168

Doi: 10.1038/s41586-025-08898-z

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A non-tethering role for the Drosophila Pol θ linker domain in promoting damage resolution

Authors: Justin R Blanch, Nicholas Woodward, Manan Krishnamurthy, Mitch McVey

Journal: Nucleic Acids Research

PubMed ID: 40275613

Doi: 10.1093/nar/gkaf304

Products & Services: Protein Electrophoresis and Western

Discovery, Herbicidal Activity and Biosynthesis of a Novel Natural Tetramic Acid from Alternaria Species

Authors: He Wang, Yanjing Guo, Qing Liu, Jing Zhang, Qianlong Zhang, Mingying Yang, Qizhen Chen, Sheng Qiang, Bernal E Valverde, Shiguo Chen

Journal: Advanced Science

PubMed ID: 40278415

Doi: 10.1002/advs.202416188

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Novel Bivalent mRNA-LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Authors: Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan-Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar-Haim, Orit Redy-Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud

Journal: Advanced Science

PubMed ID: 40279638

Doi: 10.1002/advs.202501286

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Macrophages direct location-dependent recall of B cell memory to vaccination

Authors: Rama Dhenni, Alexandra Carey Hoppé, Arnold Reynaldi, Wunna Kyaw, Nathalie Tricia Handoko, Abigail K. Grootveld, Yuki Honda Keith, Nayan Deger Bhattacharyya, Holly I. Ahel, Aiden Josiah Telfser, Andrew N. McCorkindale, Seyhan Yazar, Christina H.T. Bui, James T. Smith, Weng Hua Khoo, Mollie Boyd, Solange Obeid, Brad Milner, Mitchell Starr, Fabienne Brilot, Tri Giang Phan

Journal: Molecular Therapy

Doi: 10.1016/j.cell.2025.04.005

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Phosphorylation dependent charge block regulate the relaxation of nuclear speckle networks

Authors: Mengjun Zhang, Zhuang Gu, Yingtian Sun, Yichen Dong, Junlin Chen, Li Shu, Suibin Ma, Jierui Guo, Yuhang Liang, Qingming Qu, Ning Fang, Chuan-Qi Zhong, Yifan Ge, Zhongwen Chen, Shaohui Huang, Xin Zhang, Bo Wang

Journal: Mol Cell

PubMed ID: 40233760

Doi: 10.1016/j.molcel.2025.03.016

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