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页码: 186/1047 每页显示数量

A BioBricks toolbox for metabolic engineering of the tetracenomycin pathway

Authors: Jennifer T Nguyen, Kennedy K Riebschleger, Katelyn V Brown, Nina M Gorgijevska, S Eric Nybo

Journal: Biotechnol J.

PubMed ID: 34719127

Doi: doi.org/10.1002/biot.202100371

Products & Services: Gene Synthesis

Design of a synthesis-friendly hypoxia-responsive promoter for cell-based therapeutics

Authors: Chee Ka Candice Lam, Kevin Truong

Journal: Eng Life Sci

PubMed ID: 34899121

Doi: 10.1002/elsc.202100045

Products & Services: PCR Cloning and Subcloning

Erratum: Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies

Authors:

Journal: Front Pharmacol

PubMed ID: 34744755

Doi: 10.3389/fphar.2021.788046

Products & Services: Peptide Synthesis

Waning humoral response 6 months after SARS-CoV-2 vaccination with the mRNA-BNT162b2 vaccine in hemodialysis patients: time for a boost

Authors: Tamara Davidovic, Judith Schimpf, Armin Abbassi-Nik, Richard Stockinger, Hannelore Sprenger-Mähr, Karl Lhotta, Emanuel Zitt

Journal: Kidney Int

PubMed ID: 34656642

Doi: 10.1016/j.kint.2021.10.006

Abnormal Blood Coagulation and Kidney Damage in Aged Hamsters Infected with Severe Acute Respiratory Syndrome Coronavirus 2

Authors: Marumi Ohno, Michihito Sasaki, Yasuko Orba, Toshiki Sekiya, Md Abdul Masum, Osamu Ichii, Tatsuya Sawamura, Akemi Kakino, Yasuhiko Suzuki, Hiroshi Kida, Hirofumi Sawa, Masashi Shingai

Journal: Viruses

PubMed ID: 34834944

Doi: 10.3390/v13112137

Products & Services: Codon Optimization

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis

Authors: Qianxing Zou, Lele Yang, Ruona Shi, Yuling Qi, Xiaofei Zhang, Huayu Qi

Journal: iScience

PubMed ID: 34825148

Doi: 10.1016/j.isci.2021.103396

Products & Services: Gene Synthesis

MYB70 modulates seed germination and root system development in

Authors: Jinpeng Wan, Ruling Wang, Ping Zhang, Liangliang Sun, Qiong Ju, Haodong Huang, Shiyou Lü, Lam-Son Tran, Jin Xu

Journal: iScience

PubMed ID: 34746697

Doi: 10.1016/j.isci.2021.103228

Products & Services: Protein and Antibody Isolation

Structure-Function Analysis of Resistance to Bamlanivimab by SARS-CoV-2 Variants Kappa, Delta, and Lambda

Authors: Shufeng Liu, Tien Huynh, Charles B Stauft, Tony T Wang, Binquan Luan

Journal: J Chem Inf Model

PubMed ID: 34648284

Doi: 10.1021/acs.jcim.1c01058

Products & Services: Recombinant Proteins

Metabolic adaptation drives arsenic trioxide resistance in acute promyelocytic leukemia

Authors: Nithya Balasundaram, Saravanan Ganesan, Ezhilarasi Chendamarai, Hamenth Kumar Palani, Arvind Venkatraman, Ansu Abu Alex, Sachin David, Swathy Palanikumar, Nair Reeshma Radhakrishnan, Mohammed Yasar M, Sanjeev Krishna, Anu Korula, Uday Kulkarni, Nancy Beryl Janet, Poonkuzhali Balasubramanian, Vikram Mathews

Journal: Blood Adv

PubMed ID: 34625794

Doi: 10.1182/bloodadvances.2021005300

Products & Services: Molecular Biology Reagents

Effect of Cotton Leafroll Dwarf Virus on Physiological Processes and Yield of Individual Cotton Plants

Authors: Ved Parkash, Divya Bhanu Sharma, John Snider, Sudeep Bag, Phillip Roberts, Afsha Tabassum, Dalton West, Sameer Khanal, Nelson Suassuna, Peng Chee

Journal: Front Plant Sci

PubMed ID: 34659302

Doi: 10.3389/fpls.2021.734386

Products & Services: Molecular Biology Reagents

NLRC4 inflammasome-dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice

Authors: Peipei Zhang, Yifei Liu, Lichen Hu, Kai Huang, Mao Hong, Yuze Wang, Xinrui Fan, Richard J Ulevitch, Jiahuai Han

Journal: Sci Adv

PubMed ID: 34678072

Doi: 10.1126/sciadv.abi9471

Products & Services: Molecular Biology Reagents

An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats

Authors: Martijn A Langereis, Irina C Albulescu, Judith Stammen-Vogelzangs, Morindy Lambregts, Ken Stachura, Suzan Miller, Angela M Bosco-Lauth, Airn E Hartwig, Stephanie M Porter, Michelle Allen, Mark Mogler, Frank J M van Kuppeveld, Berend-Jan Bosch, Paul Vermeij, Ad de Groof, Richard A Bowen, Randy Davis, Zach Xu, Ian Tarpey

Journal: npj Vaccines

PubMed ID: 34671047

Doi: 10.1038/s41541-021-00390-9

Products & Services: Recombinant Proteins

Evolutionary transcriptomics implicates new genes and pathways in human pregnancy and adverse pregnancy outcomes

Authors: Katelyn Mika, Mirna Marinić, Manvendra Singh, Joanne Muter, Jan Joris Brosens, Vincent J Lynch

Journal: Elife

PubMed ID: 34623259

Doi: 10.7554/eLife.69584

Products & Services: Plasmid DNA Preparation

The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity

Authors: Kevin J Forsberg, Danica T Schmidtke, Rachel Werther, Ruben V Uribe, Deanna Hausman, Morten O A Sommer, Barry L Stoddard, Brett K Kaiser, Harmit S Malik

Journal: PLoS Biol

PubMed ID: 34644300

Doi: 10.1371/journal.pbio.3001428

Products & Services: Mutant Libraries

Kinetochore-bound Mps1 regulates kinetochore-microtubule attachments via Ndc80 phosphorylation

Authors: Krishna K Sarangapani, Lori B Koch, Christian R Nelson, Charles L Asbury, Sue Biggins

Journal: J Cell Biol

PubMed ID: 34647959

Doi: 10.1083/jcb.202106130

Products & Services: Gene Fragments

Identifying a Ferroptosis-Related Gene Signature for Predicting Biochemical Recurrence of Prostate Cancer

Authors: Zhengtong Lv, Jianlong Wang, Xuan Wang, Miao Mo, Guyu Tang, Haozhe Xu, Jianye Wang, Yuan Li, Ming Liu

Journal: Front Cell Dev Biol

PubMed ID: 34778244

Doi: 10.3389/fcell.2021.666025

Products & Services: Gene Synthesis

Anastrozole regulates fatty acid synthase in breast cancer

Authors: Junmei Cairns, James N Ingle, Krishna R Kalari, Matthew P Goetz, Richard M Weinshilboum, Huanyao Gao, Hu Li, Mehrab Ghanat Bari, Liewei Wang

Journal: Mol Cancer Ther

PubMed ID: 34667110

Doi: 10.1158/1535-7163.MCT-21-0509

Products & Services: Mutant Libraries

CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis

Authors: Xiaoxun Li, Yajun Liang, Cheng Lian, Fangli Peng, Yansen Xiao, Yunfei He, Chengxin Ma, Yuan Wang, Peiyuan Zhang, Yuhan Deng, Yunpeng Su, Cheng Luo, Xiangyin Kong, Qingcheng Yang, Tong Liu, Guohong Hu

Journal: Theranostics

PubMed ID: 34815788

Doi: 10.7150/thno.62187

Products & Services: Catalog Peptides

Aptamer-modified biosensors to visualize neurotransmitter flux

Authors: Charlotte Moraldo, Emilie Vuille-Dit-Bille, Bajramshahe Shkodra, Tom Kloter, Nako Nakatsuka

Journal: J Neurosci Methods

PubMed ID: 34653500

Doi: 10.1016/j.jneumeth.2021.109386

Products & Services: Stable Cell Lines

Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry

Authors: Young-Jun Park, Anna De Marco, Tyler N Starr, Zhuoming Liu, Dora Pinto, Alexandra C Walls, Fabrizia Zatta, Samantha K Zepeda, John Bowen, Kaitlin S Sprouse, Anshu Joshi, Martina Giurdanella, Barbara Guarino, Julia Noack, Rana Abdelnabi, Shi-Yan Caroline Foo, Florian A Lempp, Fabio Benigni, Gyorgy Snell, Johan Neyts, Sean Pj Whelan, Herbert W Virgin, Jesse D Bloom, Davide Corti, Matteo Samuele Pizzuto, David Veesler

Journal: biorxiv

PubMed ID: 34671770

Doi: 10.1101/2021.10.13.464254

Products & Services: Gene Synthesis

Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore

Authors: Evgeniya Trofimenko, Gianvito Grasso, Mathieu Heulot, Nadja Chevalier, Marco A Deriu, Gilles Dubuis, Yoan Arribat, Marc Serulla, Sebastien Michel, Gil Vantomme, Florine Ory, Linh Chi Dam, Julien Puyal, Francesca Amati, Anita Lüthi, Andrea Danani, Christian Widmann

Journal: Elife

PubMed ID: 34713805

Doi: 10.7554/eLife.69832

Products & Services: Plasmid DNA Preparation

Combining an optimized mRNA template with a double purification process allows strong expression of transcribed mRNA

Authors: Sergio Linares-Fernández, Julien Moreno, Elise Lambert, Perrine Mercier-Gouy, Laetitia Vachez, Bernard Verrier, Jean-Yves Exposito

Journal: Mol Ther Nucleic Acids

PubMed ID: 34692232

Doi: 10.1016/j.omtn.2021.10.007

Products & Services: Gene Synthesis

Black Phosphorus Nanoparticles Promote Osteogenic Differentiation of EMSCs Through Upregulated TG2 Expression

Authors: Naiyan Lu, Xinhe Wang, Wentao Shi, Lu Bian, Xuan Zhang, Guofeng Yang, Xue Tang, Jun Wang, Yin Zou, Yuyan Weng

Journal: Nanoscale Res Lett

PubMed ID: 34637014

Doi: 10.1186/s11671-021-03610-2

Products & Services: Custom Vector Construction

In vivo Profiling of the Alk Proximitome in the Developing Drosophila Brain

Authors: Ezgi Uçkun, Georg Wolfstetter, Vimala Anthonydhason, Sanjay Kumar Sukumar, Ganesh Umapathy, Linnea Molander, Johannes Fuchs, Ruth H Palmer

Journal: J Mol Biol

PubMed ID: 34624297

Doi: 10.1016/j.jmb.2021.167282

Products & Services: Polyclonal Antibody Services

Epitopes prediction for microcystin-LR by molecular docking

Authors: Yuan Liu, Shu Liu, Chongxin Xu, Manman Lin, Yihang Li, Cheng Shen, Ying Liang, Xing Sun, Donglan Wang, Peng Lü, Xianjin Liu

Journal: Ecotoxicol Environ Saf

PubMed ID: 34717216

Doi: 10.1016/j.ecoenv.2021.112925

Products & Services: Custom Vector Construction

Quantifying oxidation of cellulose-associated glucuronoxylan by two lytic polysaccharide monooxygenases from

Authors: Olav A Hegnar, Heidi Østby, Dejan M Petrović, Lisbeth Olsson, Anikó Várnai, Vincent G H Eijsink

Journal: Appl Environ Microbiol

PubMed ID: 34613755

Doi: 10.1128/AEM.01652-21

Products & Services: Codon Optimization

Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16

Authors: Frank Kozielski, Céleste Sele, Vladimir O Talibov, Jiaqi Lou, Danni Dong, Qian Wang, Xinyue Shi, Maria Nyblom, Annika Rogstam, Tobias Krojer, Zoë Fisher, Wolfgang Knecht

Journal: RSC Chem Biol

PubMed ID: 35128408

Doi: 10.1039/d1cb00135c

Products & Services: Bacterial Expression

Effects of Distal Mutations on Ligand-Binding Affinity in Dihydrofolate Reductase

Authors: Chen-Hua Huang, Yun-Wen Chen, Tsun-Tsao Huang, Ya-Ting Kao

Journal: ACS Omega

PubMed ID: 34660967

Doi: 10.1021/acsomega.1c02995

Products & Services: Plasmid DNA Preparation

The Development of Dual Vaccines against Lumpy Skin Disease (LSD) and Bovine Ephemeral Fever (BEF)

Authors: Nicola Douglass, Ruzaiq Omar, Henry Munyanduki, Akiko Suzuki, Warren de Moor, Paidamwoyo Mutowembwa, Alri Pretorius, Tshifhiwa Nefefe, Antoinette van Schalkwyk, Pravesh Kara, Livio Heath, Anna-Lise Williamson

Journal: Vaccines (Basel)

PubMed ID: 34835146

Doi: 10.3390/vaccines9111215

Products & Services: Recombinant Proteins

Characteristics of Two Crustins from in Hydrothermal Vents

Authors: Lu-Lu Guo, Shao-Lu Wang, Fang-Chao Zhu, Feng Xue, Li-Sheng He

Journal: Mar Drugs

PubMed ID: 34822471

Doi: 10.3390/md19110600

Products & Services: Protein and Antibody Isolation

Synergistic anti-inflammatory activity of apigenin and curcumin co-encapsulated in caseins assessed with lipopolysaccharide-stimulated RAW 2647 macrophages

Authors: Shan Hong, Vermont P Dia, Qixin Zhong

Journal: Int J Biol Macromol

PubMed ID: 34717976

Doi: 10.1016/j.ijbiomac.2021.10.153

Products & Services: Protein Electrophoresis and Western

Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes

Authors: Yingying Liu, Samantha Gokhale, Jaeyong Jung, Sining Zhu, Chang Luo, Debanjan Saha, Jessie Yanxiang Guo, Huaye Zhang, Saw Kyin, Wei-Xing Zong, Eileen White, Ping Xie

Journal: Front Immunol

PubMed ID: 34745083

Doi: 10.3389/fimmu.2021.670338

Products & Services: DNA Sequencing

Derlin rhomboid pseudoproteases employ substrate engagement and lipid distortion to enable the retrotranslocation of ERAD membrane substrates

Authors: Anahita Nejatfard, Nicholas Wauer, Satarupa Bhaduri, Adam Conn, Saroj Gourkanti, Narinderbir Singh, Tiffany Kuo, Rachel Kandel, Rommie E Amaro, Sonya E Neal

Journal: Cell Rep

PubMed ID: 34686332

Doi: 10.1016/j.celrep.2021.109840

Products & Services: Catalog Antibodies

Aberrant RNA methylation triggers recruitment of an alkylation repair complex

Authors: Ning Tsao, Joshua R Brickner, Rebecca Rodell, Adit Ganguly, Matthew Wood, Clement Oyeniran, Tanveer Ahmad, Hua Sun, Albino Bacolla, Lisheng Zhang, Valentina Lukinović, Jennifer M Soll, Brittany A Townley, Alexandre G Casanova, John A Tainer, Chuan He, Alessandro Vindigni, Nicolas Reynoird, Nima Mosammaparast

Journal: Mol Cell

PubMed ID: 34686315

Doi: 10.1016/j.molcel.2021.09.024

Products & Services: Gene Synthesis

Domain Analysis and Motif Matcher (DAMM): A Program to Predict Selectivity Determinants in PDZ Domains Using Human PDZ Data

Authors: Haley A Wofford, Josh Myers-Dean, Brandon A Vogel, Kevin Alexander Estrada Alamo, Frederick A Longshore-Neate, Filip Jagodzinski, Jeanine F Amacher

Journal: Molecules

PubMed ID: 34641578

Doi: 10.3390/molecules26196034

Products & Services: Gene Synthesis

Ambient Temperature Stable, Scalable COVID-19 Polymer Particle Vaccines Induce Protective Immunity

Authors: Shuxiong Chen, Benjamin Evert, Adetayo Adeniyi, Mercè Salla-Martret, Linda H-L Lua, Victoria Ozberk, Manisha Pandey, Michael F Good, Andreas Suhrbier, Peter Halfmann, Yoshihiro Kawaoka, Bernd H A Rehm

Journal: Adv Healthc Mater

PubMed ID: 34716678

Doi: 10.1002/adhm.202102089

Products & Services: Recombinant Proteins

Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase

Authors: Heather E Upton, Lucas Ferguson, Morayma M Temoche-Diaz, Xiao-Man Liu, Sydney C Pimentel, Nicholas T Ingolia, Randy Schekman, Kathleen Collins

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34649994

Doi: 10.1073/pnas.2107900118

Products & Services: ORF cDNA Clones/MolecularCloud

Impact of C-terminal truncations in the Arabidopsis Rab escort protein (REP) on REP-Rab interaction and plant fertility

Authors: Małgorzata Gutkowska, Magdalena Kaus-Drobek, Marta Hoffman-Sommer, Magdalena Małgorzata Pamuła, Anna Daria Leja, Małgorzata Perycz, Małgorzata Lichocka, Agnieszka Witek, Magdalena Wojtas, Michał Dadlez, Ewa Swiezewska, Liliana Surmacz

Journal: Plant J

PubMed ID: 34592024

Doi: 10.1111/tpj.15519

Products & Services: Monoclonal Antibody Services

The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome

Authors: Ivo A Hendriks, Sara C Buch-Larsen, Evgeniia Prokhorova, Jonas D Elsborg, Alexandra K L F S Rebak, Kang Zhu, Dragana Ahel, Claudia Lukas, Ivan Ahel, Michael L Nielsen

Journal: Nat Commun

PubMed ID: 34625544

Doi: 10.1038/s41467-021-26172-4

Products & Services: Molecular Biology Reagents

A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG

Authors: María-Natalia Lisa, Adrià Sogues, Nathalie Barilone, Meike Baumgart, Magdalena Gil, Martín Graña, Rosario Durán, Ricardo M Biondi, Marco Bellinzoni, Michael Bott, Pedro M Alzari

Journal: MBio

PubMed ID: 34607462

Doi: 10.1128/mBio.01717-21

Products & Services: Molecular Biology Reagents

Molecular switches regulating the potency and immune evasiveness of SARS-CoV-2 spike protein

Authors: Yushun Wan, Linfen Huang, Xiujuan Zhang, Jian Shang, Stanley Perlman, Lanying Du, Fang Li

Journal: Res Sq

PubMed ID: 34611654

Doi: 10.21203/rs.3.rs-736159/v2

Products & Services: Mammalian Expression

Smart exosomes with lymph node homing and immune-amplifying capacities for enhanced immunotherapy of metastatic breast cancer

Authors: Panpan Ji, Zheng Yang, Hua Li, Mengying Wei, Guodong Yang, Helin Xing, Qiuyun Li

Journal: Mol Ther Nucleic Acids

PubMed ID: 34760340

Doi: 10.1016/j.omtn.2021.10.009

Products & Services: Gene Synthesis

p53 Transactivation Domain Mediates Binding and Phase Separation with Poly-PR/GR

Authors: Sinem Usluer, Emil Spreitzer, Benjamin Bourgeois, Tobias Madl

Journal: Int J Mol Sci

PubMed ID: 34768862

Doi: 10.3390/ijms222111431

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A unique cell wall synthetic response evoked by glucosamine determines pathogenicity-associated fungal cellular differentiation

Authors: Pengjie Hu, Hao Ding, Lan Shen, Guang-Jun He, Huimin Liu, Xiuyun Tian, Changyu Tao, Xiangzheng Bai, Jingnan Liang, Cheng Jin, Xinping Xu, Ence Yang, Linqi Wang

Journal: PLoS Genet

PubMed ID: 34624015

Doi: 10.1371/journal.pgen.1009817

Products & Services: Monoclonal Antibody Services

F-NMR reveals substrate specificity of CYP121A1 in Mycobacterium tuberculosis

Authors: Christopher S Campomizzi, George E Ghanatios, D Fernando Estrada

Journal: J Biol Chem

PubMed ID: 34634307

Doi: 10.1016/j.jbc.2021.101287

Products & Services: Mutagenesis Services

Novel Thermophilic Bacterial Laccase for the Degradation of Aromatic Organic Pollutants

Authors: Nabangshu Sharma, Ivanhoe K H Leung

Journal: Front Chem

PubMed ID: 34746090

Doi: 10.3389/fchem.2021.711345

Products & Services: Plasmid DNA Preparation

Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression

Authors: Gloria Gamiz-Arco, Valeria A Risso, Eric A Gaucher, Jose A Gavira, Athi N Naganathan, Beatriz Ibarra-Molero, Jose M Sanchez-Ruiz

Journal: J Mol Biol

PubMed ID: 34687715

Doi: 10.1016/j.jmb.2021.167321

Products & Services: Plasmid DNA Preparation

Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring

Authors: Fengzhen Cui, Qingfei Pan, Siyi Wang, Faming Zhao, Runxin Wang, Tingting Zhang, Yaying Song, Jun He, Haolin Zhang, Qiang Weng, Yang Jin, Wei Xia, Yuanyuan Li, Guo-Yuan Yang, Winnok H De Vos, Jean-Pierre Timmermans, Shunqing Xu, Yaohui Tang, Xia Sheng

Journal: Adv Sci (Weinh)

PubMed ID: 34713618

Doi: 10.1002/advs.202102686

Products & Services: Gene Synthesis

Non-canonical activation of the ER stress sensor ATF6 by effectors

Authors: Nnejiuwa U Ibe, Advait Subramanian, Shaeri Mukherjee

Journal: Life Sci Alliance

PubMed ID: 34635501

Doi: 10.26508/lsa.202101247

Products & Services: Mutant Libraries

Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling

Authors: Jiajia Wang, Jiaying Wang, Wenxiang Hong, Lulu Zhang, Liqian Song, Qi Shi, Yanfei Shao, Guifeng Hao, Chunyan Fang, Yueping Qiu, Lijun Yang, Zhaoxu Yang, Jincheng Wang, Ji Cao, Bo Yang, Qiaojun He, Qinjie Weng

Journal: Nat Commun

PubMed ID: 34707127

Doi: 10.1038/s41467-021-26477-4

Products & Services: Plasmid DNA Preparation