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African Swine Fever Virus pE199L Induces Mitochondrial-Dependent Apoptosis
Authors: Tingting Li, Gaihong Zhao, Taoqing Zhang, Zhaoxia Zhang, Xin Chen, Jie Song, Xiao Wang, Jiangnan Li, Li Huang, Lili Wen, Changyao Li, Dongming Zhao, Xijun He, Zhigao Bu, Jun Zheng, Changjiang Weng
Journal: Viruses
PubMed ID: 34835046
Doi: 10.3390/v13112240
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5' Half of specific tRNAs feeds back to promote corresponding tRNA gene transcription in vertebrate embryos
Authors: Luxi Chen, Wei Xu, Kunpeng Liu, Zheng Jiang, Yang Han, Hongbin Jin, Lin Zhang, Weimin Shen, Shunji Jia, Qianwen Sun, Anming Meng
Journal: Sci Adv
PubMed ID: 34797706
Doi: 10.1126/sciadv.abh0494
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Cyclophilin A is a key positive and negative feedback regulator within interleukin-6 trans-signaling pathway
Authors: Xiaohan Luan, Wenxian Yang, Xiaoyuan Bai, Heqiao Li, Huizi Li, Wenhui Fan, He Zhang, Wenjun Liu, Lei Sun
Journal: FASEB J
PubMed ID: 34606626
Doi: 10.1096/fj.202101044RRR
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A structural feature of Dda helicase which enhances displacement of streptavidin and trp repressor from DNA
Authors: Alicia K Byrd, Emory G Malone, Lindsey Hazeslip, Maroof Khan Zafar, David K Harrison, Matthew D Thompson, Jun Gao, Senthil K Perumal, John C Marecki, Kevin D Raney
Journal: Protein Sci
PubMed ID: 34761452
Doi: 10.1002/pro.4232
Products & Services: Codon Optimization   
Identification and Characterization of Antigen-Specific CD8 T Cells Using Surface-Trapped TNF-α and Single-Cell Sequencing
Authors: Shaheed Abdulhaqq, Abigail B Ventura, Jason S Reed, Arman A Bashirova, Katherine B Bateman, Eric McDonald, Helen L Wu, Justin M Greene, John B Schell, David Morrow, Karin Wisskirchen, Jeffrey N Martin, Steven G Deeks, Mary Carrington, Ulrike Protzer, Klaus Früh, Scott G Hansen, Louis J Picker, Jonah B Sacha, Benjamin N Bimber
Journal: J Immunol
PubMed ID: 34810222
Doi: 10.4049/jimmunol.2100535
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The Ionic Selectivity of Lysenin Channels in Open and Sub-Conducting States
Authors: Andrew Bogard, Pangaea W Finn, Fulton McKinney, Ilinca M Flacau, Aviana R Smith, Rosey Whiting, Daniel Fologea
Journal: Membranes (Basel)
PubMed ID: 34832126
Doi: 10.3390/membranes11110897
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SARS-CoV-2 Infection of Rhesus Macaques Treated Early with Human COVID-19 Convalescent Plasma
Authors: Jesse D Deere, Timothy D Carroll, Joseph Dutra, Linda Fritts, Rebecca Lee Sammak, JoAnn L Yee, Katherine J Olstad, J Rachel Reader, Amy Kistler, Jack Kamm, Clara Di Germanio, Yashavanth Shaan Lakshmanappa, Sonny R Elizaldi, Jamin W Roh, Graham Simmons, Jennifer Watanabe, Rachel E Pollard, Jodie Usachenko, Ramya Immareddy, Brian A Schmidt, Shelby L O'Connor, Joseph DeRisi, Michael P Busch, Smita S Iyer, Koen K A Van Rompay, Dennis J Hartigan-O'Connor, Christopher J Miller
Journal: Microbiol Spectr
PubMed ID: 34817208
Doi: 10.1128/Spectrum.01397-21
Products & Services: Recombinant Proteins   
Retinol-Binding Protein 4 Promotes Cardiac Injury After Myocardial Infarction Via Inducing Cardiomyocyte Pyroptosis Through an Interaction With NLRP3
Authors: Kang-Zhen Zhang, Xi-Yu Shen, Man Wang, Li Wang, Hui-Xian Sun, Xiu-Zhen Li, Jing-Jing Huang, Xiao-Qing Li, Cheng Wu, Can Zhao, Jia-Li Liu, Xiang Lu, Wei Gao
Journal: J Am Heart Assoc
PubMed ID: 34726071
Doi: 10.1161/JAHA.121.022011
Products & Services: Recombinant Proteins   Protein Tools   
Management of COVID patients with convalescent plasma: Do we have the final word?
Authors: Francesco Menichetti, Marco Falcone, Giusy Tiseo
Journal: Eur J Intern Med
PubMed ID: 34895816
Doi: 10.1016/j.ejim.2021.10.029
Products & Services: Recombinant Proteins   
A study of cobalt (II) complexes involved in marine biogeochemical processes: Co(II)-1,10-Phenanthroline and Co(II)-1,10-Phenanthroline-L-α-Phosphatidylcholine
Authors: Anđela Bačinić, Sanja Frka, Marina Mlakar
Journal: Bioelectrochemistry
PubMed ID: 34902665
Doi: 10.1016/j.bioelechem.2021.108009
Products & Services: Peptide Synthesis   
Immunotherapeutic Targeting of Mesothelin Positive Pediatric AML Using Bispecific T Cell Engaging Antibodies
Authors: Anilkumar Gopalakrishnapillai, Colin E Correnti, Kristina Pilat, Ida Lin, Man Kid Chan, Ashok D Bandaranayake, Christopher Mehlin, Anne Kisielewski, Darcy Hamill, Allison J Kaeding, Soheil Meshinchi, James M Olson, Edward Anders Kolb, Sonali P Barwe
Journal: Cancers (Basel)
PubMed ID: 34885074
Doi: 10.3390/cancers13235964
Products & Services: Gene Synthesis   
Overexpression of N-acetylglucosaminyltransferase V promotes human parotid gland acinar cell immortalization via the epidermal receptor activation
Authors: Ching-Chia Cheng, Chih-Feng Lin, Yong-Chong Lin, Tai-Horng Young, Pei-Jen Lou
Journal: J Cell Physiol
PubMed ID: 34806177
Doi: 10.1002/jcp.30641
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Nucleic Acid Delivery from Granular Hydrogels
Authors: Evan Kurt, Tatiana Segura
Journal: Adv Healthc Mater
PubMed ID: 34742164
Doi: 10.1002/adhm.202101867
Products & Services: Protein and Antibody Isolation   
Assembly of pH-Responsive Antibody-Drug-Inspired Conjugates
Authors: Marco Raabe, Astrid Johanna Heck, Siska Führer, Dominik Schauenburg, Michaela Pieszka, Tao Wang, Maksymilian Marek Zegota, Lutz Nuhn, David Y W Ng, Seah Ling Kuan, Tanja Weil
Journal: Macromol Biosci
PubMed ID: 34791790
Doi: 10.1002/mabi.202100299
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A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation
Authors: Juan Luis Pacheco-Garcia, Dmitry Loginov, Bruno Rizzuti, Pavla Vankova, Jose L Neira, Daniel Kavan, Noel Mesa-Torres, Rita Guzzi, Petr Man, Angel L Pey
Journal: FEBS Lett
PubMed ID: 34817874
Doi: 10.1002/1873-3468.14238
Products & Services: Gene Synthesis   
Genomic structure, expression, and functional characterization of the Fem-1 gene family in the redclaw crayfish, Cherax quadricarinatus
Authors: Jianbo Zheng, Leran Chen, Yongyi Jia, Meili Chi, Fei Li, Shun Cheng, Shili Liu, Yinuo Liu, Zhimin Gu
Journal: Gen Comp Endocrinol
PubMed ID: 34861280
Doi: 10.1016/j.ygcen.2021.113961
Products & Services: Gene Synthesis   
Commensal Strains Enhance the Efficacy of Neo-Epitope Based Cancer Vaccines
Authors: Michele Tomasi, Mattia Dalsass, Francesco Beghini, Ilaria Zanella, Elena Caproni, Laura Fantappiè, Assunta Gagliardi, Carmela Irene, Enrico König, Luca Frattini, Giulia Masetti, Samine Jessica Isaac, Federica Armanini, Fabio Cumbo, Aitor Blanco-Míguez, Alberto Grandi, Nicola Segata, Guido Grandi
Journal: Vaccines (Basel)
PubMed ID: 34835287
Doi: 10.3390/vaccines9111356
Products & Services: Peptide Synthesis   
Quantifying charge state heterogeneity for proteins with multiple ionizable residues
Authors: Martin J Fossat, Ammon E Posey, Rohit V Pappu
Journal: Biophys J
PubMed ID: 34826385
Doi: 10.1016/j.bpj.2021.11.2886
Products & Services: Peptide Synthesis   
Silencing of SBF2-AS1 inhibits cell growth and invasion by sponging microRNA-338-3p in serous ovarian carcinoma
Authors: Ai-Ai Luan, Ling-Ling Hou, Fang-Yuan Zhang
Journal: Kaohsiung J Med Sci
PubMed ID: 34850542
Doi: 10.1002/kjm2.12479
Products & Services: Gene Synthesis   
Dl-3-N-Butylphthalide Attenuates Hypoxic Injury of Neural Stem Cells by Increasing Hypoxia-Inducible Factor-1alpha
Authors: Chaoqun Lin, Shiying Huang, Jianfeng Zhang, Huaitao Yuan, Tuchao Yao, Lukui Chen
Journal: J Stroke Cerebrovasc Dis
PubMed ID: 34837757
Doi: 10.1016/j.jstrokecerebrovasdis.2021.106221
Products & Services: Gene Synthesis   
The Hydrogen-Coupled Oligopeptide Membrane Cotransporter Pept2 is SUMOylated in Kidney Distal Convoluted Tubule Cells
Authors: Takwa S Aroankins, Sathish K Murali, Robert A Fenton, Qi Wu
Journal: Front Mol Biosci
PubMed ID: 34881291
Doi: 10.3389/fmolb.2021.790606
Products & Services: Gene Synthesis   
Characterization of the interaction domains between the phosphoprotein and the nucleoprotein of human Metapneumovirus
Authors: Hortense Decool, Benjamin Bardiaux, Luis Checa Ruano, Olivier Sperandio, Jenna Fix, Irina Gutsche, Charles-Adrien Richard, Monika Bajorek, Jean-François Eléouët, Marie Galloux
Journal: J Virol
PubMed ID: 34730389
Doi: 10.1128/JVI.00909-21
Products & Services: Gene Synthesis   
Neural-Cadherin Influences the Homing of Terminally Differentiated Memory CD8 T Cells to the Lymph Nodes and Bone Marrow
Authors: Kyong Hoon Kim, Aryeong Choi, Sang Hoon Kim, Heonju Song, Seohoon Jin, Kyungim Kim, Jaebong Jang, Hanbyeul Choi, Yong Woo Jung
Journal: Mol Cells
PubMed ID: 34819396
Doi: 10.14348/molcells.2021.0137
Products & Services: Peptide Synthesis   
Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia
Authors: Ting Zhu, Bo Liu, Di Wu, Gang Xu, Yang Fan
Journal: Front Cell Dev Biol
PubMed ID: 34869326
Doi: 10.3389/fcell.2021.740884
Products & Services: Custom DNA/RNA Oligos   
Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy
Authors: Sheng-Li Ming , Shuang Zhang , Qi Wang , Lei Zeng , Lu-Yu Zhou , Meng-Di Wang , Ying-Xian Ma , Li-Qiang Han , Kai Zhong , He-Shui Zhu , Yi-Lin Bai , Guo-Yu Yang , Jiang Wang , Bei-Bei Chu
Journal: Autophagy
PubMed ID: 34822318
Doi: 10.1080/15548627.2021.2002101
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Novel xylan-degrading enzymes from polysaccharide utilizing loci of Prevotella copri DSM18205
Authors: Javier A Linares-Pastén , Johan Sebastian Hero , José Horacio Pisa , Cristina Teixeira , Margareta Nyman , Patrick Adlercreutz , M Alejandra Martinez , Eva Nordberg Karlsson
Journal: Glycobiology
PubMed ID: 34142143
Doi: 10.1093/glycob/cwab056
Products & Services: Gene Synthesis   
Biophysical Characterization of Iron-Sulfur Proteins
Authors: Bhanu P Jagilinki, Irina Paluy, Alexei M Tyryshkin, Vikas Nanda, Dror Noy
Journal: Bio Protoc
PubMed ID: 34761074
Doi: 10.21769/BioProtoc.4202
Products & Services: Plasmid DNA Preparation   
Identification of Novel, Immunogenic HLA-DR-Presented Prevotella copri Peptides in Patients With Rheumatoid Arthritis
Authors: Annalisa Pianta, Geena Chiumento, Kristina Ramsden, Qi Wang, Klemen Strle, Sheila Arvikar, Catherine E Costello, Allen C Steere
Journal: Arthritis Rheumatol
PubMed ID: 34042327
Doi: 10.1002/art.41807
Products & Services: Bacterial Expression   
Anticancer properties of colicin E7 against colon cancer
Authors: Morovat Taherikalani, Sobhan Ghafourian
Journal: Prz Gastroenterol
PubMed ID: 34976246
Doi: 10.5114/pg.2021.109622
Products & Services: Custom DNA/RNA Oligos   
Comparative transcriptome analysis uncovers cell wall reorganization and repressed cell division during cotton fiber initiation
Authors: Wenyuan Liu, Yanjia Lv, Xiaoyue Li, Zongqin Feng, Lichen Wang
Journal: BMC Dev Biol
PubMed ID: 34715791
Doi: 10.1186/s12861-021-00247-3
Products & Services: Custom DNA/RNA Oligos   
Reprogramming the metabolism of PCC 6803 by regulating the plastoquinone biosynthesis
Authors: Jianhua Fan, Dongqing Zhou, Cheng Chen, Ju Wu, Hui Wu
Journal: Synth Syst Biotechnol
PubMed ID: 34754966
Doi: 10.1016/j.synbio.2021.10.004
Products & Services: Codon Optimization   
A BK channel-targeted peptide induces age-dependent improvement in behavioral and neural sound representation
Authors: Elliott J Brecht, Luisa L Scott, Bo Ding, Xiaoxia Zhu, Joseph P Walton
Journal: Neurobiol Aging
PubMed ID: 34861480
Doi: 10.1016/j.neurobiolaging.2021.10.014
Products & Services: Protein and Antibody Isolation   
Overexpression of the Ginkgo biloba WD40 gene GbLWD1-like improves salt tolerance in transgenic Populus
Authors: Yue Xin, Yaqiong Wu, Xin Han, Li-An Xu
Journal: Plant Sci
PubMed ID: 34763876
Doi: 10.1016/j.plantsci.2021.111092
Products & Services: Bacterial Expression   
WSB1 regulates c-Myc expression through -catenin signaling and forms a feedforward circuit
Authors: Xiaomeng Gao, Jieqiong You, Yanling Gong, Meng Yuan, Haiying Zhu, Liang Fang, Hong Zhu, Meidan Ying, Qiaojun He, Bo Yang, Ji Cao
Journal: Acta Pharm Sin B
PubMed ID: 35530152
Doi: 10.1016/j.apsb.2021.10.021
Products & Services: Catalog Antibodies   
Prior infection with SARS-CoV-2 boosts and broadens Ad26COV2S immunogenicity in a variant-dependent manner
Authors: Roanne Keeton, Simone I Richardson, Thandeka Moyo-Gwete, Tandile Hermanus, Marius B Tincho, Ntombi Benede, Nelia P Manamela, Richard Baguma, Zanele Makhado, Amkele Ngomti, Thopisang Motlou, Mathilda Mennen, Lionel Chinhoyi, Sango Skelem, Hazel Maboreke, Deelan Doolabh, Arash Iranzadeh, Ashley D Otter, Tim Brooks, Mahdad Noursadeghi, James C Moon, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Jonathan Blackburn, Nei-Yuan Hsiao, Carolyn Williamson, Catherine Riou, Ameena Goga, Nigel Garrett, Linda-Gail Bekker, Glenda Gray, Ntobeko A B Ntusi, Penny L Moore, Wendy A Burgers
Journal: Cell Host Microbe
PubMed ID: 34688376
Doi: 10.1016/j.chom.2021.10.003
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An inducible -Cre mouse model to monitor and manipulate -highly-expressing senescent cells
Authors: Binsheng Wang, Lichao Wang, Nathan S Gasek, Yueying Zhou, Taewan Kim, Chun Guo, Evan R Jellison, Laura Haynes, Sumit Yadav, Tamar Tchkonia, George A Kuchel, James L Kirkland, Ming Xu
Journal: Nat Aging
PubMed ID: 35024619
Doi: 10.1038/s43587-021-00107-6
Products & Services: Gene Fragments   
Drug Repurposing for the SARS-CoV-2 Papain-Like Protease
Authors: Chia-Chuan Cho, Shuhua G Li, Tyler J Lalonde, Kai S Yang, Ge Yu, Yuchen Qiao, Shiqing Xu, Wenshe Ray Liu
Journal: ChemMedChem
PubMed ID: 34423563
Doi: 10.1002/cmdc.202100455
Products & Services: Protein and Antibody Isolation   
Guillain-​Barré Syndrome Associated with COVID-19 Vaccination
Authors: Shih-Chieh Shao, Chien-Ho Wang, Kai-Cheng Chang, Ming-Jui Hung, Hui-Yu Chen, Shu-Chen Liao
Journal: Emerg Infect Dis
PubMed ID: 34648420
Doi: 10.3201/eid2712.211634
Products & Services: Protein and Antibody Isolation   
Reconstitution of Caveolin-1 into Artificial Lipid Membrane: Characterization by Transmission Electron Microscopy and Solid-State Nuclear Magnetic Resonance
Authors: Yanli Zhang, Xinyan Zhang, Wenru Kong, Shuqi Wang
Journal: Molecules
PubMed ID: 34684779
Doi: 10.3390/molecules26206201
Products & Services: Bacterial Expression   
Using Continuous Directed Evolution to Improve Enzymes for Plant Applications
Authors: Jorge D García-García, Kristen Van Gelder, Jaya Joshi, Ulschan Bathe, Bryan J Leong, Steven D Bruner, Chang C Liu, Andrew D Hanson
Journal: Plant Physiol
PubMed ID: 34718794
Doi: 10.1093/plphys/kiab500
Products & Services: Recombinant Antibody Expression   
Ethylene Induced by Sound Stimulation Enhances Anthocyanin Accumulation in Grape Berry Skin through Direct Upregulation of UDP-Glucose: Flavonoid 3--Glucosyltransferase
Authors: Mone Yamazaki, Akari Ishida, Yutaka Suzuki, Yoshinao Aoki, Shunji Suzuki, Shinichi Enoki
Journal: Cells
PubMed ID: 34685779
Doi: 10.3390/cells10102799
Products & Services: Molecular Biology Reagents   
Polymersomes as Stable Nanocarriers for a Highly Immunogenic and Durable SARS-CoV-2 Spike Protein Subunit Vaccine
Authors: Jian Hang Lam, Amit K Khan, Thomas A Cornell, Teck Wan Chia, Regine J Dress, Wen Wang William Yeow, Nur Khairiah Mohd-Ismail, Shrinivas Venkataraman, Kim Tien Ng, Yee-Joo Tan, Danielle E Anderson, Florent Ginhoux, Madhavan Nallani
Journal: ACS Nano
PubMed ID: 34618423
Doi: 10.1021/acsnano.1c01243
Products & Services: Recombinant Antibody Expression   
Cowpea Mosaic Virus Nanoparticle Vaccine Candidates Displaying Peptide Epitopes Can Neutralize the Severe Acute Respiratory Syndrome Coronavirus
Authors: Oscar A Ortega-Rivera, Sourabh Shukla, Matthew D Shin, Angela Chen, Veronique Beiss, Miguel A Moreno-Gonzalez, Yi Zheng, Alex E Clark, Aaron F Carlin, Jonathan K Pokorski, Nicole F Steinmetz
Journal: ACS Infect Dis
PubMed ID: 34672530
Doi: 10.1021/acsinfecdis.1c00410
Products & Services: Peptide Synthesis   
Recombinant expression of insoluble enzymes in Escherichia coli: a systematic review of experimental design and its manufacturing implications
Authors: Suraj Mital, Graham Christie, Duygu Dikicioglu
Journal: Microb Cell Fact
PubMed ID: 34717620
Doi: 10.1186/s12934-021-01698-w
Products & Services: Molecular Biology Reagents   
Hantaviruses use the endogenous host factor P58IPK to combat the PKR antiviral response
Authors: Zekun Wang, Songyang Ren, Qiming Li, Austin D Royster, Lei Lin, Sichen Liu, Safder S Ganaie, Jianming Qiu, Sheema Mir, Mohammad A Mir
Journal: PLoS Pathog
PubMed ID: 34653226
Doi: 10.1371/journal.ppat.1010007
Products & Services: Molecular Biology Reagents   
Enzymatic extraction improves intracellular protein recovery from the industrial carrageenan seaweed revealed by quantitative, subcellular protein profiling: A high potential source of functional food ingredients
Authors: Simon Gregersen, Anne-Sofie Havgaard Kongsted, Rikke Brønnum Nielsen, Søren Storck Hansen, Frederik Andersen Lau, Jacob Bisgaard Rasmussen, Susan Løvstad Holdt, Charlotte Jacobsen
Journal: Food Chem X
PubMed ID: 34746746
Doi: 10.1016/j.fochx.2021.100137
Products & Services: Protein and Antibody Isolation   
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy
Authors: Allison J Greaney, Tyler N Starr, Rachel T Eguia, Andrea N Loes, Khadija Khan, Farina Karim, Sandile Cele, John E Bowen, Jennifer K Logue, Davide Corti, David Veesler, Helen Y Chu, Alex Sigal, Jesse D Bloom
Journal: biorxiv
PubMed ID: 34671768
Doi: 10.1101/2021.10.12.464114
Products & Services: Protein and Antibody Isolation   
Bivalent individualization during chromosome territory formation in Drosophila spermatocytes by controlled condensin II protein activity and additional force generators
Authors: Luisa Vernizzi, Christian F Lehner
Journal: PLoS Genet
PubMed ID: 34669718
Doi: 10.1371/journal.pgen.1009870
Products & Services: Gene Fragments   
The Bacterial Amyloids Phenol Soluble Modulins from Catalyze Alpha-Synuclein Aggregation
Authors: Caroline Haikal, Lei Ortigosa-Pascual, Zahra Najarzadeh, Katja Bernfur, Alexander Svanbergsson, Daniel E Otzen, Sara Linse, Jia-Yi Li
Journal: Int J Mol Sci
PubMed ID: 34769023
Doi: 10.3390/ijms222111594
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Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells
Authors: Hillary H Le, Suleyman S Cinaroglu, Elise C Manalo, Aysegul Ors, Michelle M Gomes, Burcin Duan Sahbaz, Karla Bonic, Carlos A Origel Marmolejo, Arnaud Quentel, Justin S Plaut, Taryn E Kawashima, E Sila Ozdemir, Sanjay V Malhotra, Yavuz Ahiska, Ugur Sezerman, Gunseli Bayram Akcapinar, Joshua C Saldivar, Emel Timucin, Jared M Fischer
Journal: EBioMedicine
PubMed ID: 34689087
Doi: 10.1016/j.ebiom.2021.103646
Products & Services: Protein and Antibody Isolation   
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