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Fungal Pathogen Emergence: Investigations with an × Hybrid

Authors: Emilee R M Storfie, Barry J Saville

Journal: J Fungi (Basel)

PubMed ID: 34436211

Doi: 10.3390/jof7080672

Products & Services: PCR Cloning and Subcloning

A Therapeutic Hepatitis B Virus DNA Vaccine Induces Specific Immune Responses in Mice and Non-Human Primates

Authors: Dorien De Pooter, Ellen Van Gulck, Antony Chen, Claire F Evans, Jean-Marc Neefs, Helen Horton, Daniel Boden

Journal: Vaccines (Basel)

PubMed ID: 34579206

Doi: 10.3390/vaccines9090969

Products & Services: PCR Cloning and Subcloning

The c824C>A and c616dupA mutations in the SLC17a8 gene are associated with auditory neuropathy and lead to defective expression of VGluT3

Authors: Yue Qi, Shusheng Gong, Ke Liu, Yueshuai Song

Journal: Neuroreport

PubMed ID: 34145196

Doi: 10.1097/WNR.0000000000001687

Products & Services: Gene Synthesis

Development of a Multiplex Bead Assay To Detect Immunoglobulin G Antibodies to in Human Serum

Authors: Yong Wang, TaLesa Aderohunmu, Henry Bishop, Isabel McAuliffe, Hilda N Rivera, Darlyne Smith, Patricia P Wilkins, Katherine E Bowden, Matthew S Reed, Pavel Svoboda, Olga Stuchlik, Jan Pohl, Ryan E Wiegand, Sukwan Handali

Journal: J Clin Microbiol

PubMed ID: 34432487

Doi: 10.1128/JCM.00458-21

Products & Services: DNA Sequencing Gene Synthesis PCR Cloning and Subcloning

Structural elements determining the transglycosylating activity of glycoside hydrolase family 57 glycogen branching enzymes

Authors: Gang Xiang, Hans Leemhuis, Marc Jos Elise Cornelis van der Maarel

Journal: Proteins

PubMed ID: 34346105

Doi: 10.1002/prot.26200

Products & Services: Plasmid DNA Preparation

A Single-Cycle Influenza A Virus-Based SARS-CoV-2 Vaccine Elicits Potent Immune Responses in a Mouse Model

Authors: Surapong Koonpaew, Challika Kaewborisuth, Kanjana Srisutthisamphan, Asawin Wanitchang, Theeradej Thaweerattanasinp, Janya Saenboonrueng, Sukontip Poonsuk, Juggragarn Jengarn, Ratchanont Viriyakitkosol, Jarin Kramyu, Anan Jongkaewwattana

Journal: Vaccines (Basel)

PubMed ID: 34451975

Doi: 10.3390/vaccines9080850

Products & Services: Plasmid DNA Preparation

Tracking the Amide I and αCOO- Terminal ν(C=O) Raman Bands in a Family of l-Glutamic Acid-Containing Peptide Fragments: A Raman and DFT Study

Authors: Ashley E Williams, Nathan I Hammer, Ryan C Fortenberry, Dana N Reinemann

Journal: Molecules

PubMed ID: 34443382

Doi: 10.3390/molecules26164790

Products & Services: Catalog Peptides

Inhibition of the HIF-1α/BNIP3 pathway has a retinal neuroprotective effect

Authors: Hiromitsu Kunimi, Deokho Lee, Mari Ibuki, Yusaku Katada, Kazuno Negishi, Kazuo Tsubota, Toshihide Kurihara

Journal: FASEB J

PubMed ID: 34314069

Doi: 10.1096/fj.202100572R

Products & Services: Plasmid DNA Preparation

Adsorption of Recombinant Human β-Defensin 2 and Two Mutants on Mesoporous Silica Nanoparticles and Its Effect against subsp

Authors: Gabriel Marcelino-Pérez, Roberto Ruiz-Medrano, Salvador Gallardo-Hernández, Beatriz Xoconostle-Cázares

Journal: Nanomaterials (Basel)

PubMed ID: 34443974

Doi: 10.3390/nano11082144

Products & Services: Plasmid DNA Preparation

Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection

Authors: Audrey V Parent, Gaetano Faleo, Jessica Chavez, Michael Saxton, David I Berrios, Natanya R Kerper, Qizhi Tang, Matthias Hebrok

Journal: Cell Rep

PubMed ID: 34407395

Doi: 10.1016/j.celrep.2021.109538

Products & Services: Catalog Peptides

Failure of Diphtheria Toxin Model to Induce Parkinson-Like Behavior in Mice

Authors: Lucie Valek, Irmgard Tegeder

Journal: Int J Mol Sci

PubMed ID: 34502404

Doi: 10.3390/ijms22179496

Products & Services: Endotoxin Detection & Removal System

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

Authors: Juan Luis Pacheco-Garcia, Ernesto Anoz-Carbonell, Pavla Vankova, Adithi Kannan, Rogelio Palomino-Morales, Noel Mesa-Torres, Eduardo Salido, Petr Man, Milagros Medina, Athi N Naganathan, Angel L Pey

Journal: Redox Biol

PubMed ID: 34537677

Doi: 10.1016/j.redox.2021.102112

Products & Services: Mutagenesis Services

An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates

Authors: Nerea Zabaleta, Wenlong Dai, Urja Bhatt, Cécile Hérate, Pauline Maisonnasse, Jessica A Chichester, Julio Sanmiguel, Reynette Estelien, Kristofer T Michalson, Cheikh Diop, Dawid Maciorowski, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Thibaut Naninck, Nidhal Kahlaoui, Julien Lemaitre, Wenbin Qi, Elissa Hudspeth, Allison Cucalon, Cecilia D Dyer, M Betina Pampena, James J Knox, Regina C LaRocque, Richelle C Charles, Dan Li, Maya Kim, Abigail Sheridan, Nadia Storm, Rebecca I Johnson, Jared Feldman, Blake M Hauser, Vanessa Contreras, Romain Marlin, Raphaël Ho Tsong Fang, Catherine Chapon, Sylvie van der Werf, Eric Zinn, Aisling Ryan, Dione T Kobayashi, Ruchi Chauhan, Marion McGlynn, Edward T Ryan, Aaron G Schmidt, Brian Price, Anna Honko, Anthony Griffiths, Sam Yaghmour, Robert Hodge, Michael R Betts, Mason W Freeman, James M Wilson, Roger Le Grand, Luk H Vandenberghe

Journal: Cell Host Microbe

PubMed ID: 34428428

Doi: 10.1016/j.chom.2021.08.002

Products & Services: Monoclonal Antibody Services

TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity

Authors: Sarah C Atkinson, Steven M Heaton, Michelle D Audsley, Oded Kleifeld, Natalie A Borg

Journal: Int J Mol Sci

PubMed ID: 34445801

Doi: 10.3390/ijms22169094

Products & Services: Bacterial Expression

Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination

Authors: Matthew J Gorman, Nita Patel, Mimi Guebre-Xabier, Alex L Zhu, Caroline Atyeo, Krista M Pullen, Carolin Loos, Yenny Goez-Gazi, Ricardo Carrion, Jing-Hui Tian, Dansu Yuan, Kathryn A Bowman, Bin Zhou, Sonia Maciejewski, Marisa E McGrath, James Logue, Matthew B Frieman, David Montefiori, Colin Mann, Sharon Schendel, Fatima Amanat, Florian Krammer, Erica Ollmann Saphire, Douglas A Lauffenburger, Ann M Greene, Alyse D Portnoff, Michael J Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Galit Alter

Journal: Cell Rep Med

PubMed ID: 34485950

Doi: 10.1016/j.xcrm.2021.100405

Products & Services: Insect Expression

Genome-wide identification of the MADS-box transcription factor family in autotetraploid cultivated alfalfa (Medicago sativa L) and expression analysis under abiotic stress

Authors: Xueming Dong, Hao Deng, Wenxue Ma, Qiang Zhou, Zhipeng Liu

Journal: BMC Genomics

PubMed ID: 34362293

Doi: 10.1186/s12864-021-07911-9

Products & Services: Protein Tools

Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex

Authors: Weifeng Liu, Zachary Maben, Carole Wang, Kevin C Lindquist, Manqing Li, Vinayak Rayannavar, Ilsel Lopez Armenta, Andrew Nager, Edward Pascua, Pawel K Dominik, David Oyen, Hui Wang, Rachel Carson Roach, Corey M Allan, Lidia Mosyak, Javier Chaparro-Riggers

Journal: J Biol Chem

PubMed ID: 34419446

Doi: 10.1016/j.jbc.2021.101102

Products & Services: Polyclonal Antibody Services

Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis

Authors: Chun Gong, Joanna A Krupka, Jie Gao, Nicholas F Grigoropoulos, George Giotopoulos, Ryan Asby, Michael Screen, Zelvera Usheva, Francesco Cucco, Sharon Barrans, Daniel Painter, Nurmahirah Binte Mohammed Zaini, Björn Haupl, Susanne Bornelöv, Igor Ruiz De Los Mozos, Wei Meng, Peixun Zhou, Alex E Blain, Sorcha Forde, Jamie Matthews, Michelle Guet Khim Tan, G A Amos Burke, Siu Kwan Sze, Philip Beer, Cathy Burton, Peter Campbell, Vikki Rand, Suzanne D Turner, Jernej Ule, Eve Roman, Reuben Tooze, Thomas Oellerich, Brian J Huntly, Martin Turner, Ming-Qing Du, Shamith A Samarajiwa, Daniel J Hodson

Journal: Mol Cell

PubMed ID: 34437837

Doi: 10.1016/j.molcel.2021.07.041

Products & Services: Polyclonal Antibody Services

Haploinsufficiency of SF3B2 causes craniofacial microsomia

Authors: Andrew T Timberlake, Casey Griffin, Carrie L Heike, Anne V Hing, Michael L Cunningham, David Chitayat, Mark R Davis, Soghra J Doust, Amelia F Drake, Milagros M Duenas-Roque, Jack Goldblatt, Jonas A Gustafson, Paula Hurtado-Villa, Alexis Johns, Natalya Karp, Nigel G Laing, Leanne Magee, Sureni V Mullegama, Harry Pachajoa, Gloria L Porras-Hurtado, Rhonda E Schnur, Jennie Slee, Steven L Singer, David A Staffenberg, Andrew E Timms, Cheryl A Wise, Ignacio Zarante, Jean-Pierre Saint-Jeannet, Daniela V Luquetti

Journal: Nat Commun

PubMed ID: 34344887

Doi: 10.1038/s41467-021-24852-9

Products & Services: Mammalian Expression

Structure of autoinhibited Akt1 reveals mechanism of PIP-mediated activation

Authors: Linda Truebestein, Harald Hornegger, Dorothea Anrather, Markus Hartl, Kaelin D Fleming, Jordan T B Stariha, Els Pardon, Jan Steyaert, John E Burke, Thomas A Leonard

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34385319

Doi: 10.1073/pnas.2101496118

Products & Services: Proteins, Expression, Isolation and Analysis

Longitudinal analysis to characterize classes and subclasses of antibody responses to recombinant receptor-binding protein (RBD) of SARS-CoV-2 in COVID-19 patients in Thailand

Authors: Sarunporn Tandhavanant, Sirikamon Koosakunirand, Taniya Kaewarpai, Watcharapong Piyaphanee, Pornsawan Leaungwutiwong, Viravarn Luvira, Narisara Chantratita

Journal: PLoS ONE

PubMed ID: 34375345

Doi: 10.1371/journal.pone.0255796

Products & Services: Recombinant Antibody Expression

JA signal-mediated immunity of Dendrobium catenatum to necrotrophic Southern Blight pathogen

Authors: Cong Li, Qiuyi Shen, Xiang Cai, Danni Lai, Lingshang Wu, Zhigang Han, Tianlun Zhao, Donghong Chen, Jinping Si

Journal: BMC Plant Biol

PubMed ID: 34362300

Doi: 10.1186/s12870-021-03134-y

Products & Services: Protein Tools

A Split-Cre system designed to detect simultaneous expression of two genes based on SpyTag/SpyCatcher conjugation and Split-GFP dimerization

Authors: Xundong Wei, Jianhua Zhang, Jian Cui, Wei Xu, Xuyu Zhou, Jie Ma

Journal: J Biol Chem

PubMed ID: 34450162

Doi: 10.1016/j.jbc.2021.101119

Products & Services: Custom Vector Construction

Phosphorylation of Androgen Receptor by mTORC1 Promotes Liver Steatosis and Tumorigenesis

Authors: Qian-Nan Ren, Hong Zhang, Chao-Yue Sun, Yu-Feng Zhou, Xue-Feng Yang, Jian-Wu Long, Xiao-Xing Li, Shi-Juan Mai, Mei-Yin Zhang, Hui-Zhong Zhang, Hai-Qiang Mai, Min-Shan Chen, X F Steven Zheng, Hui-Yun Wang

Journal: Hepatology

PubMed ID: 34435708

Doi: 10.1002/hep.32120

Products & Services: Catalog Peptides

Pyrophosphate release acts as a kinetic checkpoint during high-fidelity DNA replication by the Staphylococcus aureus replicative polymerase PolC

Authors: Sean P Fagan, Purba Mukherjee, William J Jaremko, Rachel Nelson-Rigg, Ryan C Wilson, Tyler L Dangerfield, Kenneth A Johnson, Indrajit Lahiri, Janice D Pata

Journal: Nucleic Acids Res

PubMed ID: 34302475

Doi: 10.1093/nar/gkab613

Products & Services: Bacterial Expression

Expression of heat-resistant β-glucosidase in and its application in the production of gardenia blue

Authors: Wenxi Li, Jielin Li, Ying Xu, Yan Huang, Shuqi Xu, Zirui Ou, Xiaoli Long, Xinyu Li, Xinyu Liu, Zening Xiao, Jiaqi Huang, Weizhao Chen

Journal: Synth Syst Biotechnol

PubMed ID: 34504963

Doi: 10.1016/j.synbio.2021.08.002

Products & Services: ORF cDNA Clones/MolecularCloud

SARS-CoV-2 neutralizing antibodies after first vaccination dose in breast cancer patients receiving CDK4/6 inhibitors

Authors: Flora Zagouri, Evangelos Terpos, Oraianthi Fiste, Michalis Liontos, Alexandros Briasoulis, Ioanna Katsiana, Efi Skafida, Christos Markellos, Elena Kunadis, Angeliki Andrikopoulou, Maria Kaparelou, Konstantinos Koutsoukos, Maria Gavriatopoulou, Efstathios Kastritis, Ioannis P Trougakos, Meletios-Athanasios Dimopoulos

Journal: Breast

PubMed ID: 34481366

Doi: 10.1016/j.breast.2021.08.017

Products & Services: PCR and Cloning

Profiling CD8 T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants

Authors: Hang Zhang, Shasha Deng, Liting Ren, Peiyi Zheng, Xiaowen Hu, Tengchuan Jin, Xu Tan

Journal: Cell Rep

PubMed ID: 34506741

Doi: 10.1016/j.celrep.2021.109708

Products & Services: Peptide Synthesis

The neutralizing antibody response post COVID-19 vaccination in patients with myeloma is highly dependent on the type of anti-myeloma treatment

Authors: Evangelos Terpos, Maria Gavriatopoulou, Ioannis Ntanasis-Stathopoulos, Alexandros Briasoulis, Sentiljana Gumeni, Panagiotis Malandrakis, Despina Fotiou, Eleni-Dimitra Papanagnou, Magdalini Migkou, Foteini Theodorakakou, Maria Roussou, Evangelos Eleutherakis-Papaiakovou, Nikolaos Kanellias, Ioannis P Trougakos, Efstathios Kastritis, Meletios A Dimopoulos

Journal: Blood Cancer J

PubMed ID: 34341335

Doi: 10.1038/s41408-021-00530-3

7-Ethoxyrosmanol alleviates hyperglycemia-induced vascular endothelial dysfunction by regulating FBXL7 expression

Authors: Jianqi Ni, Lan Shen, Liu Xu, Qin Jin, Guoliang Wang

Journal: J Bioenerg Biomembr

PubMed ID: 34427826

Doi: 10.1007/s10863-021-09916-1

Products & Services: Plasmid DNA Preparation

SARS-CoV-2 disease severity and transmission efficiency is increased for airborne compared to fomite exposure in Syrian hamsters

Authors: Julia R Port, Claude Kwe Yinda, Irene Offei Owusu, Myndi Holbrook, Robert Fischer, Trenton Bushmaker, Victoria A Avanzato, Jonathan E Schulz, Craig Martens, Neeltje van Doremalen, Chad S Clancy, Vincent J Munster

Journal: Nat Commun

PubMed ID: 34404778

Doi: 10.1038/s41467-021-25156-8

Products & Services: Custom Vector Construction

miR-33a-5p inhibits the progression of esophageal cancer through the DKK1-mediated Wnt/β-catenin pathway

Authors: Qingping Song, Hui Liu, Chengyan Li, Haifeng Liang

Journal: Aging (Albany NY)

PubMed ID: 34426559

Doi: 10.18632/aging.203430

Products & Services: Custom DNA/RNA Oligos

Insertion of prpoD_rpoS fragment enhances expression of recombinant protein by dps auto-inducible promoter in Escherichia coli

Authors: Dina Mulyanti, Sundani Nurono Soewandhi, Catur Riani

Journal: Mol Biol Rep

PubMed ID: 34342815

Doi: 10.1007/s11033-021-06562-z

Products & Services: Plasmid DNA Preparation

Genome Editing in Zebrafish by ScCas9 Recognizing NNG PAM

Authors: Yunxing Liu , Fang Liang , Zijiong Dong , Song Li , Jianmin Ye and Wei Qin

Journal: Cells

PubMed ID: 34440868

Doi: 10.3390/cells10082099

Products & Services: Gene Services

Subtype-selective positive modulation of K Ca 2 channels depends on the HA/HB helices

Authors: Young-Woo Nam，Meng Cui， Naglaa Salem，Razan Orfali，Misa Nguyen， Grace Yang，Mohammad Asikur Rahman， Judy Lee，Miao Zhang

Journal: British Journal of Pharmacol

PubMed ID: 34458981

Doi: 10.1111/bph.15676

Products & Services: Gene Synthesis

Comparability of six different immunoassays measuring SARS-CoV-2 antibodies with neutralizing antibody levels in convalescent plasma: From utility to prediction

Authors: Abigail Lamikanra, Dung Nguyen, Peter Simmonds, Sarah Williams, Emma M Bentley, Cathy Rowe, Ashley David Otter, Tim Brooks, Kimberly Gilmour, Annabelle Mai, Jusvinder Dadhra, Mabel Csatari, Sheba Ziyenge, Marta Oliveira, Rutger Ploeg, Pat Tsang, Maria Zambon, Robin Gopal, Julie Huiyuan Xiao, Alain Townsend, David Roberts, Heli Harvala

Journal: Transfusion

PubMed ID: 34342366

Doi: 10.1111/trf.16600

Products & Services: SARS-CoV-2 qRT-PCR Detection Assay

Light-Induced Dynamic Change of Phytochrome B and Cryptochrome 1 Stabilizes SINATs in

Authors: Jin Hu, Yinmeng Hu, Mengran Yang, Xiaotong Hu, Xuelu Wang

Journal: Front Plant Sci

PubMed ID: 34490020

Doi: 10.3389/fpls.2021.722733

Products & Services: Proteins, Expression, Isolation and Analysis

The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis

Authors: Amanda J Morris, Lindsay Jackson, Yvonne Cw Yau, Courtney Reichhardt, Trevor Beaudoin, Stephanie Uwumarenogie, Kevin M Guttman, P Lynne Howell, Matthew R Parsek, Lucas R Hoffman, Dao Nguyen, Antonio DiGiandomenico, David S Guttman, Daniel J Wozniak, Valerie J Waters

Journal: NPJ Biofilms Microbiomes

PubMed ID: 34349133

Doi: 10.1038/s41522-021-00234-3

Products & Services: Proteins, Expression, Isolation and Analysis

Recombinase polymerase amplification (RPA) with lateral flow detection for three Anaplasma species of importance to livestock health

Authors: Andrea Salazar, Francisco M Ochoa-Corona, Justin L Talley, Bruce H Noden

Journal: Sci Rep

PubMed ID: 34354122

Doi: 10.1038/s41598-021-95402-y

Products & Services: Proteins, Expression, Isolation and Analysis

CD27 expression on Treg cells limits immune responses against tumors

Authors: Sabine Muth, Annekatrin Klaric, Markus Radsak, Hansjörg Schild, Hans Christian Probst