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Development and Characterization of Magnetic SARS-CoV-2 Peptide-Imprinted Polymers

Authors: Beatriz Fresco-Cala, Soumya Rajpal, Tamara Rudolf, Benedikt Keitel, Rüdiger Groß, Jan Münch, Alex D Batista, Boris Mizaikoff

Journal: Nanomaterials (Basel)

PubMed ID: 34835749

Doi: 10.3390/nano11112985

Products & Services: Catalog Peptides

EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1

Authors: Toshinori Ando, Nadia Arang, Zhiyong Wang, Daniela Elena Costea, Xiaodong Feng, Yusuke Goto, Hiroki Izumi, Mara Gilardi, Kazuyo Ando, J Silvio Gutkind

Journal: Commun Biol

PubMed ID: 34725466

Doi: 10.1038/s42003-021-02744-4

Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

Authors: Daniel Franjic, Mario Skarica, Shaojie Ma, Jon I Arellano, Andrew T N Tebbenkamp, Jinmyung Choi, Chuan Xu, Qian Li, Yury M Morozov, David Andrijevic, Zvonimir Vrselja, Ana Spajic, Gabriel Santpere, Mingfeng Li, Shupei Zhang, Yang Liu, Joshua Spurrier, Le Zhang, Ivan Gudelj, Lucija Rapan, Hideyuki Takahashi, Anita Huttner, Rong Fan, Stephen M Strittmatter, Andre M M Sousa, Pasko Rakic, Nenad Sestan

Journal: Neuron

PubMed ID: 34798047

Doi: 10.1016/j.neuron.2021.10.036

Products & Services: Recombinant Antibody Expression

BNT162b2 vaccine induces divergent B cell responses to SARS-CoV-2 S1 and S2

Authors: R Camille Brewer, Nitya S Ramadoss, Lauren J Lahey, Shaghayegh Jahanbani, William H Robinson, Tobias V Lanz

Journal: Nat Immunol

PubMed ID: 34848871

Doi: 10.1038/s41590-021-01088-9

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ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals

Authors: Natalya Pashkova, Lokesh Gakhar, Liping Yu, Nicholas J Schnicker, Annabel Y Minard, Stanley Winistorfer, Ivan E Johnson, Robert C Piper

Journal: Elife

PubMed ID: 34821552

Doi: 10.7554/eLife.72583

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Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2

Authors: Xudong Chen, Mingze Zhou, Sensen Zhang, Jian Yin, Ping Zhang, Xujun Xuan, Peiyi Wang, Zhiqiang Liu, Boda Zhou, Maojun Yang

Journal: Cell Discov

PubMed ID: 34728622

Doi: 10.1038/s41421-021-00334-6

Products & Services: Protein and Antibody Isolation

Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells

Authors: Opeyemi S Adeniji, Leticia Kuri-Cervantes, Chenfei Yu, Ziyang Xu, Michelle Ho, Glen M Chew, Cecilia Shikuma, Costin Tomescu, Ashley F George, Nadia R Roan, Lishomwa C Ndhlovu, Qin Liu, Kar Muthumani, David B Weiner, Michael R Betts, Han Xiao, Mohamed Abdel-Mohsen

Journal: PLoS Pathog

PubMed ID: 34762717

Doi: 10.1371/journal.ppat.1010034

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Dual regulatory actions of LncBMP4 on BMP4 promote chicken primordial germ cell formation

Authors: Qisheng Zuo, Jin Jing, Jing Zhou, Yani Zhang, Wanhong Wei, Guohong Chen, Bichun Li

Journal: EMBO Rep

PubMed ID: 34747116

Doi: 10.15252/embr.202152491

Products & Services: Protein and Antibody Isolation

Genome-Wide Identification, Characterization and Expression Analysis of Soybean Gene Family

Authors: Bowei Jia, Yan Wang, Dajian Zhang, Wanhong Li, Hongli Cui, Jun Jin, Xiaoxi Cai, Yang Shen, Shengyang Wu, Yongxia Guo, Mingzhe Sun, Xiaoli Sun

Journal: Int J Mol Sci

PubMed ID: 34830077

Doi: 10.3390/ijms222212192

Products & Services: Protein Tools

Multicellular Ovarian Cancer Model for Evaluation of Nanovector Delivery in Ascites and Metastatic Environments

Authors: Stephen J Winter, Hunter A Miller, Jill M Steinbach-Rankins

Journal: Pharmaceutics

PubMed ID: 34834307

Doi: 10.3390/pharmaceutics13111891

Products & Services: Recombinant Proteins

Understanding the Role of Genus in the Digestion of Lignocellulose and Other Substrates in Vietnamese Native Goats' Rumen by Metagenomic Deep Sequencing

Authors: Trong-Khoa Dao, Thi-Huyen Do, Ngoc-Giang Le, Hong-Duong Nguyen, Thi-Quy Nguyen, Thi-Thu-Hong Le, Nam-Hai Truong

Journal: Animals (Basel)

PubMed ID: 34827987

Doi: 10.3390/ani11113257

Products & Services: Gene Synthesis

Development and characterization of SARS-CoV-2 variant-neutralizing monoclonal antibodies

Authors: Hongyu Qiu, Xin-Yong Yuan, Teresa Cabral, Kathy Manguiat, Alyssia Robinson, Heidi Wood, Chris Grant, Peter McQueen, Garrett Westmacott, Daniel R Beniac, Lisa Lin, Michael Carpenter, Darwyn Kobasa, Tom Gräfenhan

Journal: Antiviral Res

PubMed ID: 34762975

Doi: 10.1016/j.antiviral.2021.105206

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Tau-tubulin kinase 1 phosphorylates TDP-43 at disease-relevant sites and exacerbates TDP-43 pathology

Authors: Yuan Tian, Yi Wang, Angela M Jablonski, Yinghui Hu, Jonathan A Sugam, Markus Koglin, Shawn J Stachel, Heather Zhou, Jason M Uslaner, Sophie Parmentier-Batteur

Journal: Neurobiol Dis

PubMed ID: 34752923

Doi: 10.1016/j.nbd.2021.105548

Products & Services: Plasmid DNA Preparation

Sulforaphane suppresses autophagy during the malignant progression of gastric carcinoma via activating miR-4521/PIK3R3 pathway

Authors: Zi-Tan Peng, Pei Gu

Journal: Hum Exp Toxicol

PubMed ID: 34749521

Doi: 10.1177/09603271211054437

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Fabrication of MERS-nanovesicle biosensor composed of multi-functional DNA aptamer/graphene-MoS nanocomposite based on electrochemical and surface-enhanced Raman spectroscopy

Authors: Gahyeon Kim, Jinmyeong Kim, Soo Min Kim, Tatsuya Kato, Jinho Yoon, Seungwoo Noh, Enoch Y Park, Chulhwan Park, Taek Lee, Jeong-Woo Choi

Journal: Sens Actuators B Chem

PubMed ID: 34785863

Doi: 10.1016/j.snb.2021.131060

Products & Services: Recombinant Proteins

Biosynthesis of Poly(3HB--3HP) with Variable Monomer Composition in Recombinant H16

Authors: Callum McGregor, Nigel P Minton, Katalin Kovács

Journal: ACS Synth Biol

PubMed ID: 34762808

Doi: 10.1021/acssynbio.1c00283

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LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy

Authors: Pin Li, Qin Li, Nilima Biswas, Hong Xin, Tanja Diemer, Lixian Liu, Lorena Perez Gutierrez, Giovanni Paternostro, Carlo Piermarocchi, Sergii Domanskyi, Ruikang K Wang, Napoleone Ferrara

Journal: EMBO Mol Med

PubMed ID: 34779136

Doi: 10.15252/emmm.202114511

Products & Services: Gene Fragments

A Genome-Phenome Association study in native microbiomes identifies a mechanism for cytosine modification in DNA and RNA

Authors: Weiwei Yang, Yu-Cheng Lin, William Johnson, Nan Dai, Romualdas Vaisvila, Peter Weigele, Yan-Jiun Lee, Ivan R Corrêa, Ira Schildkraut, Laurence Ettwiller

Journal: Elife

PubMed ID: 34747693

Doi: 10.7554/eLife.70021

Products & Services: Plasmid DNA Preparation

Bend family proteins mark chromatin boundaries and synergistically promote early germ cell differentiation

Authors: Guang Shi, Yaofu Bai, Xiya Zhang, Junfeng Su, Junjie Pang, Quanyuan He, Pengguihang Zeng, Junjun Ding, Yuanyan Xiong, Jingran Zhang, Jingwen Wang, Dan Liu, Wenbin Ma, Junjiu Huang, Zhou Songyang

Journal: Protein Cell

PubMed ID: 34731408

Doi: 10.1007/s13238-021-00884-1

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Genome-wide identification and characteristic analysis of the downstream melatonin metabolism gene GhM2H in Gossypium hirsutum L

Authors: Yuexin Zhang, Jing Wang, Xiugui Chen, Xuke Lu, Delong Wang, Junjuan Wang, Shuai Wang, Chao Chen, Lixue Guo, Waqar Afzal Malik, Yapeng Fan, Cun Rui, Ruifeng Cui, Qinqin Wang, Yuqian Lei, Wuwei Ye

Journal: Biol Res

PubMed ID: 34736526

Doi: 10.1186/s40659-021-00358-y

Products & Services: Molecular Biology Tools

Poor neutralizing antibody responses in 106 patients with WM after vaccination against SARS-CoV-2: a prospective study

Authors: Maria Gavriatopoulou, Evangelos Terpos, Ioannis Ntanasis-Stathopoulos, Alexandros Briasoulis, Sentiljana Gumeni, Panagiotis Malandrakis, Despina Fotiou, Magdalini Migkou, Foteini Theodorakakou, Evangelos Eleutherakis-Papaiakovou, Nikolaos Kanellias, Efstathios Kastritis, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: Blood Adv

PubMed ID: 34529762

Doi: 10.1182/bloodadvances.2021005444

Critical cysteines in the functional interaction of adenylyl cyclase isoform 6 with Gαs

Authors: Anjali Y Bhagirath, Vikram Bhatia, Manoj Reddy Medapati, Nisha Singh, Martha Hinton, Prashen Chelikani, Shyamala Dakshinamurti

Journal: FASEB Bioadv

PubMed ID: 35664968

Doi: 10.1096/fba.2021-00073

Products & Services: Mammalian Expression

Fasudil prevents neomycin-induced hair cell damage by inhibiting autophagy through the miR-489/NDP52 signaling pathway in HEI-OC1 cells

Authors: Wei Li, Yanqiu Zhang, Jifeng Xu, Jincan Chen, Xia Gao

Journal: Exp Ther Med

PubMed ID: 34849158

Doi: 10.3892/etm.2021.10965

Products & Services: Plasmid DNA Preparation

The effect of Borago officinalis on the signaling pathway of the NLRP3 inflammasome complex, TLR4 and some inflammatory cytokines in type II diabetic patients with acute respiratory distress syndrome

Authors: Yanqiu Yue, Fengbin Jin, Xiaohui Yue

Journal: Cell Mol Biol (Noisy-le-grand)

PubMed ID: 34933712

Doi: 10.14715/cmb/2021.67.3.28

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SNHG17, as an EMT-related lncRNA, promotes the expression of c-Myc by binding to c-Jun in esophageal squamous cell carcinoma

Authors: Supeng Shen, Jia Liang, Xiaoliang Liang, Gaoyan Wang, Bo Feng, Wei Guo, Yanli Guo, Zhiming Dong

Journal: Cancer Sci

PubMed ID: 34714590

Doi: 10.1111/cas.15184

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Biophysical analysis of the Mycobacteria tuberculosis peptide binding protein DppA reveals a stringent peptide binding pocket

Authors: Dinesh M Fernando, Clifford T Gee, Elizabeth C Griffith, Christopher J Meyer, Laura A Wilt, Rajendra Tangallapally, Miranda J Wallace, Darcie J Miller, Richard E Lee

Journal: Tuberculosis (Edinb)

PubMed ID: 34894561

Doi: 10.1016/j.tube.2021.102157

Products & Services: Bacterial Expression

JNK/Itch Axis Mediates the Lipopolysaccharide-Induced Ubiquitin-Proteasome-Dependent Degradation of Ferritin Light Chain in Murine Macrophage Cells

Authors: Shufen He, Jianqi Xue, Pengxiu Cao, Jianyuan Hou, Yan Cui, Jing Chang, Liying Huang, Yu Han, Xianglin Duan, Ke Tan, Yumei Fan

Journal: Inflammation

PubMed ID: 34837126

Doi: 10.1007/s10753-021-01603-y

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Phylogenetic Analysis of the Plant U2 snRNP Auxiliary Factor Large Subunit A Gene Family in Response to Developmental Cues and Environmental Stimuli

Authors: Shuai Lu, Cong Gao, Yongzhou Wang, Yingying He, Junrong Du, Moxian Chen, Hua Zhao, Hui Fang, Baohua Wang, Yunying Cao

Journal: Front Plant Sci

PubMed ID: 34868124

Doi: 10.3389/fpls.2021.739671

Products & Services: Protein Tools

A poly(ethylene glycol) three-dimensional bone marrow hydrogel

Authors: Lauren E Jansen, Hyuna Kim, Christopher L Hall, Thomas P McCarthy, Michael J Lee, Shelly R Peyton

Journal: Biomaterials

PubMed ID: 34890973

Doi: 10.1016/j.biomaterials.2021.121270

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Wilavidin - a novel member of the avidin family that forms unique biotin-binding hexamers

Authors: Orly Avraham, Edward A Bayer, Oded Livnah

Journal: FEBS J

PubMed ID: 34726340

Doi: 10.1111/febs.16259

Products & Services: Codon Optimization

Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease

Authors: Marcel V Alavi

Journal: Biochim Biophys Acta Mol Cell Res.

PubMed ID: 34400172

Doi: 10.1016/j.bbamcr.2021.119116

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Cyclic peptides with a distinct arginine-fork motif recognize the HIV trans-activation response RNA in vitro and in cells

Authors: Sai Shashank Chavali, Sachitanand M Mali, Rachel Bonn, Abhijith Saseendran Anitha, Ryan P Bennett, Harold C Smith, Rudi Fasan, Joseph E Wedekind

Journal: J Biol Chem.

PubMed ID: 34767799

Doi: 10.1016/j.jbc.2021.101390

Products & Services: Peptide Synthesis

Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants

Authors: Matthew McCallum, Alexandra C Walls, Kaitlin R Sprouse, John E Bowen, Laura E Rosen, Ha V Dang, Anna De Marco, Nicholas Franko, Sasha W Tilles, Jennifer Logue, Marcos C Miranda, Margaret Ahlrichs, Lauren Carter, Gyorgy Snell, Matteo Samuele Pizzuto, Helen Y Chu, Wesley C Van Voorhis, Davide Corti, David Veesler

Journal: Science

PubMed ID: 34751595

Doi: 10.1126/science.abl8506

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Immune Responses to a Single Dose of the AZD1222/Covishield Vaccine at 16 Weeks in Individuals in Sri Lanka

Authors: Chandima Jeewandara, Dinuka Guruge, Pradeep Darshana Pushpakumara, Achala Kamaladasa, Inoka Sepali Aberathna, Shyrar Tanussiya Ramu, Banuri Gunasekera, Ayesha Wijesinghe, Osanda Dissanayake, Heshan Kuruppu, Thushali Ranasinghe, Deshni Jayathilaka, Shashika Dayarathna, Dinithi Ekanayake, Jeewantha Jayamali, Nayanathara Gamalath, Anushika Mudunkotiwa, Gayasha Somathilake, Madhushika Dissanayake, Michael Harvie, Thashmi Nimasha, Deshan Madusanka, Tibutius Jayadas, Ruwan Wijayamuni, Lisa Schimanski, Pramila Rijal, Tiong K Tan, Alain Townsend, Graham S Ogg, Gathsaurie Neelika Malavige

Journal: J Immunol

PubMed ID: 34750205

Doi: 10.4049/jimmunol.2100762

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α-Klotho released from HK-2 cells inhibits osteogenic differentiation of renal interstitial fibroblasts by inactivating the Wnt-β-catenin pathway

Authors: Zewu Zhu, Shuhao Ruan, Yingcheng Jiang, Fang Huang, Weiping Xia, Jinbo Chen, Yu Cui, Cheng He, Feng Zeng, Yang Li, Zhiyong Chen, Hequn Chen

Journal: Cell Mol Life Sci

PubMed ID: 34724098

Doi: 10.1007/s00018-021-03972-x

Products & Services: Protein and Antibody Isolation

Hydrolytically Stable Maleimide-End-Functionalized Polymers for Site-Specific Protein Conjugation

Authors: Thaiesha A Wright, Monica Sharfin Rahman, Camaryn Bennett, Madolynn R Johnson, Henry Fischesser, Natasha Ram, Amoni Tyler, Richard C Page, Dominik Konkolewicz

Journal: Bioconjug Chem

PubMed ID: 34730954

Doi: 10.1021/acs.bioconjchem.1c00487

Products & Services: Plasmid DNA Preparation

LDH nanoparticle adjuvant subunit vaccine induces an effective immune response for porcine epidemic diarrhea virus

Authors: Danyi Shi, Baochao Fan, Bing Sun, Jinzhu Zhou, Yongxiang Zhao, Rongli Guo, Zengjun Ma, Tao Song, Huiying Fan, Jizong Li, Li Li, Bin Li

Journal: Virology

PubMed ID: 34739917

Doi: 10.1016/j.virol.2021.10.010

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Polyactin A and CpG enhance inactivated Pseudomonas plecoglossicida vaccine potency in large yellow croaker (Larimichthys crocea)

Authors: Wenwen Wang, Wei Wang, Wenjun Xu, Qin Liu, Yuanxing Zhang, Xiaohong Liu

Journal: Fish Shellfish Immunol

PubMed ID: 34780977

Doi: 10.1016/j.fsi.2021.11.008

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STING inhibition accelerates the bone healing process while enhancing type H vessel formation

Authors: Xiaojun Chen, Wenxin He, Mengzhe Sun, Yingjie Yan, Yichuan Pang, Gang Chai

Journal: FASEB J

PubMed ID: 34694030

Doi: 10.1096/fj.202100069RR

Products & Services: Nucleic Acid Purification

Structural basis and mechanism of activation of two different families of G proteins by the same GPCR

Authors: Kamela O Alegre, Navid Paknejad, Minfei Su, Jian-Shu Lou, Jianyun Huang, Kelsey D Jordan, Edward T Eng, Joel R Meyerson, Richard K Hite, Xin-Yun Huang

Journal: Nat Struct Mol Biol

PubMed ID: 34759376

Doi: 10.1038/s41594-021-00679-2

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Circular RNA hsa_circ_0043278 inhibits breast cancer progression via the miR-455-3p/EI24 signalling pathway

Authors: Yue Shi, Chong Liu

Journal: BMC Cancer

PubMed ID: 34800978

Doi: 10.1186/s12885-021-08989-w

Products & Services: Mutant Libraries

Mapping enzyme catalysis with metabolic biosensing

Authors: Linfeng Xu, Kai-Chun Chang, Emory M Payne, Cyrus Modavi, Leqian Liu, Claire M Palmer, Nannan Tao, Hal S Alper, Robert T Kennedy, Dale S Cornett, Adam R Abate

Journal: Nat Commun

PubMed ID: 34815408

Doi: 10.1038/s41467-021-27185-9

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SpSR-B2 functions as a potential pattern recognition receptor involved in antiviral and antibacterial immune responses of mud crab Scylla paramamosain

Authors: Jian Zhou, Jun-Fang Zhou, Yue Wang, Guang-Peng Feng, Wen-Hong Fang, Wei Kang, Ling-Bo Ma, Xin-Cang Li

Journal: Int J Biol Macromol

PubMed ID: 34780895

Doi: 10.1016/j.ijbiomac.2021.11.048

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Photoredox-Catalyzed Decarboxylative -Terminal Differentiation for Bulk- and Single-Molecule Proteomics

Authors: Le Zhang, Brendan M Floyd, Maheshwerreddy Chilamari, James Mapes, Jagannath Swaminathan, Steven Bloom, Edward M Marcotte, Eric V Anslyn

Journal: ACS Chem Biol

PubMed ID: 34734691

Doi: 10.1021/acschembio.1c00631

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Elevated Fab glycosylation of anti-hinge antibodies

Authors: J Koers, Nil Derksen, Wjj Falkenburg, P Ooijevaar-de Heer, M T Nurmohamed, G J Wolbink, T Rispens

Journal: Scand J Rheumatol

PubMed ID: 34726124

Doi: 10.1080/03009742.2021.1986959

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Using recombinant adhesive proteins as durable and green flame-retardant coatings

Authors: Weng I Leong, Owen Lok In Lo, Fong Tin Cheng, Wai Man Cheong, Leo Chi U Seak

Journal: Synth Syst Biotechnol

PubMed ID: 34786512

Doi: 10.1016/j.synbio.2021.10.005

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Structure and Function of a Dual Reductase-Dehydratase Enzyme System Involved in -Terphenyl Biosynthesis

Authors: Jonathan A Clinger, Yinan Zhang, Yang Liu, Mitchell D Miller, Ronnie E Hall, Steven G Van Lanen, George N Phillips, Jon S Thorson, Sherif I Elshahawi

Journal: ACS Chem Biol

PubMed ID: 34763417

Doi: 10.1021/acschembio.1c00701

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Biodegradation of diphenyl ether herbicide lactofen by Bacillus sp YS-1 and characterization of two initial degrading esterases

Authors: Na Shang, Lingling Chen, Minggen Cheng, Yanning Tian, Xing Huang

Journal: Sci Total Environ

PubMed ID: 34742792

Doi: 10.1016/j.scitotenv.2021.151357

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Structural and functional insights into the spike protein mutations of emerging SARS-CoV-2 variants

Authors: Deepali Gupta, Priyanka Sharma, Mandeep Singh, Mukesh Kumar, A S Ethayathulla, Punit Kaur

Journal: Cell Mol Life Sci

PubMed ID: 34731254

Doi: 10.1007/s00018-021-04008-0

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Prokaryotic expression, evaluation, and prediction of the structure and function of the ecarin metalloproteinase domain

Authors: Nasrin Mohammadi, Mojgan Bandehpour, Fattah Sotoodehnejadnematalahi, Bahram Kazemi

Journal: Proteins

PubMed ID: 34739152

Doi: 10.1002/prot.26275

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