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Divergent regulation of inflammatory cytokines by mTORC1 in THP-1-derived macrophages and intestinal epithelial Caco-2 cells

Authors: Harleen Kaur, Anjeza Erickson, Régis Moreau

Journal: Life Sci

PubMed ID: 34478760

Doi: 10.1016/j.lfs.2021.119920

Grass Carp Reovirus VP56 Allies VP4, Recruits, Blocks, and Degrades RIG-I to More Effectively Attenuate IFN Responses and Facilitate Viral Evasion

Authors: Hang Su, Zhiwei Liao, Chunrong Yang, Yongan Zhang, Jianguo Su

Journal: Microbiol Spectr

PubMed ID: 34523975

Doi: 10.1128/Spectrum.01000-21

Products & Services: Recombinant Proteins

Recovery of Memory B-cell Subsets and Persistence of Antibodies in Convalescent COVID-19 Patients

Authors: Anuradha Rajamanickam, Nathella Pavan Kumar, Arul Nancy P, Nandhini Selvaraj, Saravanan Munisankar, Rachel Mariam Renji, Vijayalakshmi V, Manoj Murhekar, Jeromie Wesley Vivian Thangaraj, Muthusamy Santhosh Kumar, C P Girish Kumar, Tarun Bhatnagar, Manickam Ponnaiah, R Sabarinathan, V Saravana Kumar, Subash Babu

Journal: Am J Trop Med Hyg

PubMed ID: 34583334

Doi: 10.4269/ajtmh.21-0883

Products & Services: Recombinant Proteins

Circular RNA ERBB2 Contributes to Proliferation and Migration of Airway Smooth Muscle Cells via miR-98-5p/IGF1R Signaling in Asthma

Authors: Jun-Qian Huang, Fang Wang, Long-Tao Wang, Yong-Mei Li, Jun-Li Lu, Jian-You Chen

Journal: J Asthma Allergy

PubMed ID: 34616159

Doi: 10.2147/JAA.S326058

Products & Services: Gene Synthesis

Dnj1 Promotes Virulence in by Maintaining Robust Endoplasmic Reticulum Homeostasis Under Temperature Stress

Authors: Linda C Horianopoulos, Christopher W J Lee, Guanggan Hu, Mélissa Caza, James W Kronstad

Journal: Front Microbiol

PubMed ID: 34566931

Doi: 10.3389/fmicb.2021.727039

Products & Services: Gene Synthesis

Structural basis of an epitope tagging system derived from Haloarcula marismortui bacteriorhodopsin I D94N and its monoclonal antibody GD-26

Authors: Po-Jung Pao, Min-Feng Hsu, Ming-Hui Chiang, Chun-Ting Chen, Cheng-Chung Lee, Andrew H-J Wang

Journal: FEBS J

PubMed ID: 34499806

Doi: 10.1111/febs.16184

Products & Services: Bacterial Expression

Combinations of Single Chain Variable Fragments From HIV Broadly Neutralizing Antibodies Demonstrate High Potency and Breadth

Authors: Rebecca T van Dorsten, Kshitij Wagh, Penny L Moore, Lynn Morris

Journal: Front Immunol

PubMed ID: 34603312

Doi: 10.3389/fimmu.2021.734110

Products & Services: Gene Synthesis

ER Bodies Are Induced by and Negatively Regulate Immunity

Authors: José S Rufián, James M Elmore, Eduardo R Bejarano, Carmen R Beuzon, Gitta L Coaker

Journal: Mol Plant Microbe Interact

PubMed ID: 34110257

Doi: 10.1094/MPMI-11-20-0330-SC

Products & Services: Gene Synthesis

Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts

Authors: Anissa A Widjaja, Sivakumar Viswanathan, Dong Jinrui, Brijesh K Singh, Jessie Tan, Joyce Goh Wei Ting, David Lamb, Shamini G Shekeran, Benjamin L George, Sebastian Schafer, David Carling, Eleonora Adami, Stuart A Cook

Journal: Front Mol Biosci

PubMed ID: 34651016

Doi: 10.3389/fmolb.2021.740650

Products & Services: Gene Synthesis

Fluorometric coupled enzyme assay for N-sulfotransferase activity of N-deacetylase/N-sulfotransferase (NDST)

Authors: Joshua Atienza, Ilona Tkachyova, Michael Tropak, Xiaolian Fan, Andreas Schulze

Journal: Glycobiology

PubMed ID: 34080004

Doi: 10.1093/glycob/cwab048

Products & Services: Bacterial Expression

Identification of Circular RNAs Related to Vascular Endothelial Proliferation, Migration, and Angiogenesis After Spinal Cord Injury Using Microarray Analysis in Female Mice

Authors: Xin Ye, Yilei Chen, Jiasheng Wang, Jian Chen, Ying Yao, Lin-Lin Wang, Fengdong Zhao

Journal: Front Neurol

PubMed ID: 34539543

Doi: 10.3389/fneur.2021.666750

Products & Services: Proteins, Expression, Isolation and Analysis

Tissue dynamics of von Willebrand factor characterized by a novel fluorescent protein-von Willebrand factor chimera

Authors: Linru Xu, Yanyang Qiu, Yanqing Li, Yaxuan Wei, Yan Wan, Wei Deng

Journal: J Thromb Haemost

PubMed ID: 34592034

Doi: 10.1111/jth.15542

Products & Services: Polyclonal Antibody Services

Parasitic modulation of host development by ubiquitin-independent protein degradation

Authors: Weijie Huang, Allyson M MacLean, Akiko Sugio, Abbas Maqbool, Marco Busscher, Shu-Ting Cho, Sophien Kamoun, Chih-Horng Kuo, Richard G H Immink, Saskia A Hogenhout

Journal: Cell

PubMed ID: 34536345

Doi: 10.1016/j.cell.2021.08.029

Products & Services: Polyclonal Antibody Services

Bacterial Cytological Profiling Identifies Rhodanine-Containing PAINS Analogs as Specific Inhibitors of Thymidylate Kinase

Authors: Elizabeth T Montaño, Jason F Nideffer, Joseph Sugie, Eray Enustun, Adam B Shapiro, Hannah Tsunemoto, Alan I Derman, Kit Pogliano, Joe Pogliano

Journal: J Bacteriol

PubMed ID: 34280002

Doi: 10.1128/JB.00105-21

Products & Services: Plasmid DNA Preparation

Characterization of a Novel Shewanella algae Arginine Decarboxylase Expressed in Escherichia coli

Authors: Xiao-Dong Pei, Liang-Hua Lu, Shi-Yang Yue, Ya Li, Xiao-Ling Liu, Fan Li, Ke-Jie Wu, Cheng-Hua Wang

Journal: Mol Biotechnol

PubMed ID: 34532832

Doi: 10.1007/s12033-021-00397-6

Products & Services: Plasmid DNA Preparation

Identification of coagulation factor IX variants with enhanced activity through ancestral sequence reconstruction

Authors: Kristopher A Knight, Christopher W Coyle, Caelan E Radford, Ernest T Parker, Andrew Fedanov, Jordan M Shields, Fania Szlam, Anatolii Purchel, Michelle Chen, Gabriela Denning, Roman M Sniecinski, Pete Lollar, H Trent Spencer, Eric A Gaucher, Christopher B Doering

Journal: Blood Adv

PubMed ID: 34477814

Doi: 10.1182/bloodadvances.2021004742

Products & Services: PCR Cloning and Subcloning

The increased presence of repetitive motifs in the KDDR-plus recombinant protein, a kinesin-derived antigen from Leishmania infantum, improves the diagnostic performance of serological tests for human and canine visceral leishmaniasis

Authors: Williane Fernanda Siqueira, Agostinho Gonçalves Viana, João Luís Reis Cunha, Leticia Mansur Rosa, Lilian Lacerda Bueno, Daniella Castanheira Bartholomeu, Mariana Santos Cardoso, Ricardo Toshio Fujiwara

Journal: PLoS Negl Trop Dis

PubMed ID: 34534217

Doi: 10.1371/journal.pntd.0009759

Products & Services: PCR Cloning and Subcloning

The EDS1-PAD4-ADR1 node mediates Arabidopsis pattern-triggered immunity

Authors: Rory N Pruitt, Federica Locci, Friederike Wanke, Lisha Zhang, Svenja C Saile, Anna Joe, Darya Karelina, Chenlei Hua, Katja Fröhlich, Wei-Lin Wan, Meijuan Hu, Shaofei Rao, Sara C Stolze, Anne Harzen, Andrea A Gust, Klaus Harter, Matthieu H A J Joosten, Bart P H J Thomma, Jian-Min Zhou, Jeffery L Dangl, Detlef Weigel, Hirofumi Nakagami, Claudia Oecking, Farid El Kasmi, Jane E Parker, Thorsten Nürnberger

Journal: Nature

PubMed ID: 34497423

Doi: 10.1038/s41586-021-03829-0

Products & Services: ORF cDNA Clones/MolecularCloud

Thioredoxin reductase from Bacillus cereus exhibits distinct reduction and NADPH-binding properties

Authors: Marita Shoor, Ingvild Gudim, Hans-Petter Hersleth, Marta Hammerstad

Journal: FEBS Open Bio

PubMed ID: 34492167

Doi: 10.1002/2211-5463.13289

Products & Services: Mutant Libraries

Epitope-dependent thermodynamic signature of single-domain antibodies against hen egg lysozyme

Authors: Hiroki Akiba, Hiroko Tamura, Jose M M Caaveiro, Kouhei Tsumoto

Journal: J Biochem

PubMed ID: 34519785

Doi: 10.1093/jb/mvab082

Products & Services: Mutant Libraries

Crus2 Glycine-Rich Region Contributes Largely to the Antiviral Activity of the Whole-Protein Molecule by Interacting with VP26, a WSSV Structural Protein

Authors: Yue Wang, Chao Zhang, Wen-Hong Fang, Hong-Yu Ma, Xin-Cang Li

Journal: Mar Drugs

PubMed ID: 34677443

Doi: 10.3390/md19100544

Products & Services: Monoclonal Antibody Services

The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation

Authors: Linyu Sun, Wentao Wang, Cai Han, Wei Huang, Yumeng Sun, Ke Fang, Zhancheng Zeng, Qianqian Yang, Qi Pan, Tianqi Chen, Xuequn Luo, Yueqin Chen

Journal: Mol Cell

PubMed ID: 34555354

Doi: 10.1016/j.molcel.2021.08.033

Products & Services: Monoclonal Antibody Services

YAP facilitates melanoma migration through regulation of actin-related protein 2/3 complex subunit 5 (ARPC5)

Authors: Jason W Lui, Stephen P G Moore, Lee Huang, Kelsey Ogomori, Yan Li, Deborah Lang

Journal: Pigment Cell Melanoma Res

PubMed ID: 34468072

Doi: 10.1111/pcmr.13013

Products & Services: Molecular Biology Tools

LCZ696 Possesses a Protective Effect Against Homocysteine (Hcy)-Induced Impairment of Blood-Brain Barrier (BBB) Integrity by Increasing Occludin, Mediated by the Inhibition of Egr-1

Authors: Wenfeng Li, Wenjin Yuan, Dandan Zhang, Shuchun Cai, Jun Luo, Kanghua Zeng

Journal: Neurotox Res

PubMed ID: 34542838

Doi: 10.1007/s12640-021-00414-1

Products & Services: Molecular Biology Reagents

Critical Conditions for Studying Interleukin-11 Signaling In Vitro and Avoiding Experimental Artefacts

Authors: Sivakumar Viswanathan, Benjamin Ng, Anissa A Widjaja, Chee Jian Pua, Nevin Tham, Jessie Tan, Stuart A Cook, Sebastian Schafer

Journal: Curr Protoc

PubMed ID: 34570432

Doi: 10.1002/cpz1.251

Products & Services: Mammalian Expression

Two evolutionarily duplicated domains individually and post-transcriptionally control SWEET expression for phloem transport

Authors: Chen Zhang, Ye Li, Jiang Wang, Xueyi Xue, Gabriel Beuchat, Li-Qing Chen

Journal: New Phytol

PubMed ID: 34431115

Doi: 10.1111/nph.17688

Products & Services: GenParts™ DNA Fragments

The E3 Ubiquitin Ligase TRIM25 Inhibits Tembusu Virus Replication

Authors: Han Kaikai, Dongmin Zhao, Yuzhuo Liu, Qingtao Liu, Xinmei Huang, Jing Yang, Lijiao Zhang, Yin Li

Journal: Front Vet Sci

PubMed ID: 34595229

Doi: 10.3389/fvets.2021.722113

Products & Services: GenParts™ DNA Fragments

Estrogen-regulated AGR3 activates the estrogen receptor signaling pathway to promote tamoxifen resistance in breast cancer

Authors: Rui Jiang, Yongjie Sun, Xiao Chen, Peng Shi

Journal: Breast Cancer Res Treat

PubMed ID: 34519905

Doi: 10.1007/s10549-021-06385-3

Products & Services: Gene Synthesis

Overexpression of arogenate dehydratase reveals an upstream point of metabolic control in phenylalanine biosynthesis

Authors: Heejin Yoo, Stuti Shrivastava, Joseph H Lynch, Xing-Qi Huang, Joshua R Widhalm, Longyun Guo, Benjamin C Carter, Yichun Qian, Hiroshi A Maeda, Joseph P Ogas, John A Morgan, Amy Marshall-Colón, Natalia Dudareva

Journal: Plant J

PubMed ID: 34403557

Doi: 10.1111/tpj.15467

Products & Services: Gene Synthesis

Quorum Sensing by Gelsolin Regulates Programmed Cell Death 4 Expression and a Density-Dependent Phenotype in Macrophages

Authors: Reshma Kumari Sharma, Binita Goswami, Sukhen Das Mandal, Abhishek Guha, Belinda Willard, Partho Sarothi Ray

Journal: J Immunol.

PubMed ID: 34362832

Doi: 10.4049/jimmunol.2001392

Products & Services: ORF cDNA Clones/MolecularCloud

Molecular basis for kinin selectivity and activation of the human bradykinin receptors

Authors: Yu-Ling Yin, Chenyu Ye, Fulai Zhou, Jia Wang, Dehua Yang, Wanchao Yin, Ming-Wei Wang, H Eric Xu, Yi Jiang

Journal: Nat Struct Mol Biol .

PubMed ID: 34518695

Doi: 10.1038/s41594-021-00645-y

Products & Services: Peptide Synthesis

BORIS/CTCFL expression activates the TGFβ signaling cascade and induces Drp1 mediated mitochondrial fission in neuroblastoma

Authors: Venkata Krishna Kanth Makani, Jolly Janette Mendonza, Prajitha Mohandas Edathara, Suresh Yerramsetty, Manika Pal Bhadra

Journal: Free Radic Biol Med

PubMed ID: 34534628

Doi: 10.1016/j.freeradbiomed.2021.09.010

Products & Services: Oligo pool

pSlug immunohistochemistry is a novel promising mitotic marker for FFPE samples: a pilot study

Authors: Chang Gok Woo, Seung-Myoung Son, Young Hyun Lim, Dakeun Lee, Jung-Jin Park, Eung-Gook Kim, Eun-Young Shin, Ok-Jun Lee

Journal: Virchows Arch

PubMed ID: 34510267

Doi: 10.1007/s00428-021-03201-7

Products & Services: Catalog Peptides

Validation of an insertion-engineered isoprene synthase as a strategy to functionalize terpene synthases

Authors: C Raul Gonzalez-Esquer, Bryan Ferlez, Sarathi M Weraduwage, Henning Kirst, Alexandra T Lantz, Aiko Turmo, Thomas D Sharkey, Cheryl A Kerfeld

Journal: RSC Adv

PubMed ID: 35480253

Doi: 10.1039/d1ra05710c

Products & Services: Bacterial Expression

The Open Cell Form of 3D-Printed Titanium Improves Osteconductive Properties and Adhesion Behavior of Dental Pulp Stem Cells

Authors: Marialucia Gallorini, Susi Zara, Alessia Ricci, Francesco Guido Mangano, Amelia Cataldi, Carlo Mangano

Journal: Materials (Basel)

PubMed ID: 34576532

Doi: 10.3390/ma14185308

Products & Services: Proteins, Expression, Isolation and Analysis

The splicing regulator SLU7 is required to preserve DNMT1 protein stability and DNA methylation

Authors: Miriam Recalde, María Gárate-Rascón, María Elizalde, María Azkona, M Ujue Latasa, Marina Bárcena-Varela, Bruno Sangro, Maite G Fernández-Barrena, Matías A Ávila, María Arechederra, Carmen Berasain

Journal: Nucleic Acids Res

PubMed ID: 34331453

Doi: 10.1093/nar/gkab649

Products & Services: Plasmid DNA Preparation

Mahmoud HE, El-Far SW, Embaby AM. Cloning, expression, and in silico structural modeling of cholesterol oxidase of Acinetobacter sp. strain RAMD in E. coli.

Authors: Hoda E Mahmoud , Shaymaa W El-Far , Amira M Embaby

Journal: FEBS Open Bio .

PubMed ID: 34272838

Doi: 10.1002/2211-5463.13254

Products & Services: Custom Vector Construction

The Fish Pathogen Aliivibrio salmonicida LFI1238 Can Degrade and Metabolize Chitin despite Gene Disruption in the Chitinolytic Pathway

Authors: Anna Skåne, Giusi Minniti, Jennifer S M Loose, Sophanit Mekasha, Bastien Bissaro, Geir Mathiesen, Magnus Ø Arntzen, Gustav Vaaje-Kolstad

Journal: Appl Environ Microbiol

PubMed ID: 34319813

Doi: 10.1128/AEM.00529-21

Products & Services: Recombinant Proteins

Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization

Authors: Veronica Di Sarno, Gianluigi Lauro, Simona Musella, Tania Ciaglia, Vincenzo Vestuto, Marina Sala, Maria Carmina Scala, Gerardina Smaldone, Francesca Di Matteo, Sara Novi, Mario Felice Tecce, Ornella Moltedo, Giuseppe Bifulco, Pietro Campiglia, Isabel M Gomez-Monterrey, Robert Snoeck, Graciela Andrei, Carmine Ostacolo, Alessia Bertamino

Journal: Eur J Med Chem

PubMed ID: 34571172

Doi: 10.1016/j.ejmech.2021.113863

Products & Services: Proteins, Expression, Isolation and Analysis

Clean and folded: Production of active, high quality recombinant human interferon-λ1

Authors: Aram Shaldzhyan, Yana Zabrodskaya, Nikita Yolshin, Tatiana Kudling, Alexey Lozhkov, Marina Plotnikova, Edward Ramsay, Aleksandr Taraskin, Peter Nekrasov, Mikhail Grudinin, Andrey Vasin

Journal: Process Biochem

PubMed ID: 34493923

Doi: 10.1016/j.procbio.2021.08.029

Products & Services: Molecular Biology Tools

Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing

Authors: Qingyang Zhang, Juan Zhang, Jin Ye, Xiaohui Li, Hongda Liu, Xiaolin Ma, Chao Wang, Keqiang He, Wei Zhang, Ji Yuan, Yingjun Zhao, Huaxi Xu, Qiang Liu

Journal: Mol Neurodegener

PubMed ID: 34551807

Doi: 10.1186/s13024-021-00485-w

Products & Services: Gene Synthesis

Evaluation of bacterial hosts for conversion of lignin-derived p-coumaric acid to 4-vinylphenol

Authors: Alberto Rodriguez, Jamie A Meadows, Ning Sun, Blake A Simmons, John M Gladden

Journal: Microb Cell Fact

PubMed ID: 34526022

Doi: 10.1186/s12934-021-01670-8

Products & Services: Bacterial Expression

HIF-1α Hydroxyprolines Modulate Oxygen-Dependent Protein Stability Via Single VHL Interface With Comparable Effect on Ubiquitination Rate

Authors: Wenguang He, Sarah Batty-Stuart, Jeffrey E Lee, Michael Ohh

Journal: J Mol Biol

PubMed ID: 34537235

Doi: 10.1016/j.jmb.2021.167244

Products & Services: Peptide Synthesis

The role of DNA-binding and ARNT dimerization on the nucleo-cytoplasmic translocation of the aryl hydrocarbon receptor

Authors: Rashad Haidar, Frank Henkler, Josephine Kugler, Aline Rosin, Doris Genkinger, Peter Laux, Andreas Luch

Journal: Sci Rep

PubMed ID: 34521881

Doi: 10.1038/s41598-021-97507-w

Products & Services: Gene Synthesis

Brain adiponectin signaling controls peripheral insulin response in Drosophila

Authors: Nathalie Arquier, Marianne Bjordal, Philippe Hammann, Lauriane Kuhn, Pierre Léopold

Journal: Nat Commun

PubMed ID: 34561451

Doi: 10.1038/s41467-021-25940-6

Products & Services: Custom Vector Construction

Intradermal ChAdOx1 Vaccine Following Two CoronaVac Shots: A Case Report

Authors: Ekachai Singhatiraj, Krit Pongpirul, Anan Jongkaewwattana, Nattiya Hirankarn

Journal: Vaccines (Basel)

PubMed ID: 34579227

Doi: 10.3390/vaccines9090990

Efficient acquisition of tens of thousands of short tandem repeats in single-cell whole-genome-amplified DNA

Authors: Liming Tao, Zipora Marx, Ofir Raz, Ehud Shapiro

Journal: STAR Protoc

PubMed ID: 34585162

Doi: 10.1016/j.xpro.2021.100828

Products & Services: Custom DNA/RNA Oligos

A combination of mRNA features influence the efficiency of leaderless mRNA translation initiation

Authors: Mohammed-Husain M Bharmal, Alisa Gega, Jared M Schrader

Journal: NAR Genom Bioinform

PubMed ID: 34568822

Doi: 10.1093/nargab/lqab081

Products & Services: Mutant Libraries

Intrauterine immunizations trigger antigen-specific mucosal and systemic immunity in pigs and passive protection in suckling piglets

Authors: P Choudhary, K R Fourie, S Ng, G Hamonic, N Bérubé, Y Popowych, H L Wilson

Journal: Vaccine

PubMed ID: 34535320

Doi: 10.1016/j.vaccine.2021.08.080

Products & Services: Catalog Peptides

Wilson WRKY2 Regulates Chitinase Gene Expression During the Response to the Root Rot Pathogen

Authors: Shan Li, Jun Hai, Zie Wang, Jie Deng, Tingting Liang, Linlin Su, Diqiu Liu

Journal: Front Plant Sci

PubMed ID: 34646290

Doi: 10.3389/fpls.2021.741463

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