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页码: 172/1028 每页显示数量

Self-inhibitory peptides targeting the MtrCDE efflux pump increase antibiotic susceptibility

Authors: Benjamin J Evert, Valentin A Slesarenko, Jilsy M J Punnasseril, Jian Zhan, Yaoqi Zhou, Evgeny A Semchenko, Kate L Seib

Journal: Antimicrob Agents Chemother

PubMed ID: 34633841

Doi: 10.1128/AAC.01542-21

Products & Services: Peptide Synthesis

High salt diet-induced proximal tubular phenotypic changes and sodium-glucose cotransporter-2 expression are coordinated by cold shock Y-box binding protein-1

Authors: Anja Bernhardt, Saskia Häberer, JingJing Xu, Hannah Damerau, Johannes Steffen, Charlotte Reichardt, Katharina Wolters, Hannes Steffen, Berend Isermann, Katrin Borucki, Nadine Artelt, Nicole Endlich, Renata Kozyraki, Sabine Brandt, Jonathan A Lindquist, Peter R Mertens

Journal: FASEB J

PubMed ID: 34533842

Doi: 10.1096/fj.202100667RR

Products & Services: Proteins, Expression, Isolation and Analysis

Role of African swine fever virus (ASFV) proteins EP153R and EP402R in reducing viral persistence in blood and virulence in pigs infected with BeninΔDP148R

Authors: Vlad Petrovan, Anusyah Rathakrishnan, Muneeb Islam, Lynnette C Goatley, Katy Moffat, Pedro J Sanchez-Cordon, Ana L Reis, Linda K Dixon

Journal: J Virol

PubMed ID: 34643433

Doi: 10.1128/JVI.01340-21

Products & Services: Plasmid DNA Preparation

A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates

Authors: Chang Guo, Yanan Peng, Lin Lin, Xiaoyan Pan, Mengqi Fang, Yun Zhao, Keyan Bao, Runhan Li, Jianbao Han, Jiaorong Chen, Tian-Zhang Song, Xiao-Li Feng, Yahong Zhou, Gan Zhao, Leike Zhang, Yongtang Zheng, Ping Zhu, Haiying Hang, Linqi Zhang, Zhaolin Hua, Hongyu Deng, Baidong Hou

Journal: Cell Rep Med

PubMed ID: 34723223

Doi: 10.1016/j.xcrm.2021.100448

Products & Services: Proteins, Expression, Isolation and Analysis

Knockdown of circ_0011946 targets miR-216a-5p/BCL2L2 axis to regulate proliferation, migration, invasion and apoptosis of oral squamous cell carcinoma cells

Authors: Ying Zhou, Shuhong Zhang, Zhonghan Min, Zhongwei Yu, Huaiwei Zhang, Jiao Jiao

Journal: BMC Cancer

PubMed ID: 34620126

Doi: 10.1186/s12885-021-08779-4

Products & Services: Custom DNA/RNA Oligos

A New Hybrid Protein Is a Novel Regulator for Experimental Colitis in Rats

Authors: Kohki Okada, Masaki Ikemoto

Journal: Inflammation

PubMed ID: 34628574

Doi: 10.1007/s10753-021-01537-5

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of a P-glycoprotein drug transporter from Toxocara canis with a novel pharmacological profile

Authors: Jeba R J Jesudoss Chelladurai, Douglas E Jones, Matthew T Brewer

Journal: Int J Parasitol Drugs Drug Resist

PubMed ID: 34753107

Doi: 10.1016/j.ijpddr.2021.10.002

Products & Services: Catalog Peptides

Monitoring PD-1 Phosphorylation to Evaluate PD-1 Signaling during Antitumor Immune Responses

Authors: Xia Bu, Vikram R Juneja, Carol G Reynolds, Kathleen M Mahoney, Melissa T Bu, Kathleen A McGuire, Seth Maleri, Ping Hua, Baogong Zhu, Sarah R Klein, Edward A Greenfield, Philippe Armand, Jerome Ritz, Arlene H Sharpe, Gordon J Freeman

Journal: Cancer Immunol Res

PubMed ID: 34635486

Doi: 10.1158/2326-6066.CIR-21-0493

Products & Services: Peptide Synthesis

Enhanced bone regeneration via spatiotemporal and controlled delivery ofa genetically engineered BMP-2 in a composite Hydrogel

Authors: Xin Chen , Baoyu Tan , Zhiteng Bao , Shang Wang , Rongze Tang , Zhenmin Wang , Gaoyang Chen , Shuai Chen , William W Lu , Dazhi Yang , Songlin Peng

Journal: Biomaterials

PubMed ID: 34517277

Doi: doi.org/10.1016/j.biomaterials.2021.121117

Products & Services: Codon Optimization

Mitoxantrone dihydrochloride, an FDA approved drug, binds with SARS-CoV-2 NSP1 C-terminal

Authors: Prateek Kumar, ProfileTaniya Bhardwaj, ProfileRajanish Giri

Journal: biorxiv

Doi: doi.org/10.1101/2021.09.14.460211

Products & Services: Peptide Synthesis

Orthogonal CRISPR-associated transposases for parallel and multiplexed chromosomal integration

Authors: Siqi Yang, Yiwen Zhang, Jiaqi Xu, Jiao Zhang, Jieze Zhang, Junjie Yang, Yu Jiang, Sheng Yang

Journal: Nucleic Acids Res

PubMed ID: 34478496

Doi: 10.1093/nar/gkab752

Products & Services: Synthetic sgRNA and crRNA Service

Regulation of human mTOR complexes by DEPTOR

Authors: Matthias Wälchli, Karolin Berneiser, Francesca Mangia, Stefan Imseng, Louise-Marie Craigie, Edward Stuttfeld, Michael N Hall, Timm Maier

Journal: Elife

PubMed ID: 34519268

Doi: 10.7554/eLife.70871

Products & Services: Proteins, Expression, Isolation and Analysis

Pre-pandemic SARS-CoV-2 serological reactivity in rural malaria-experienced Cambodians

Authors: Jessica Manning, Irfan Zaidi, Chanthap Lon, Luz Angela Rosas, Jae-Keun Park, Aiyana Ponce, Jennifer Bohl, Sophana Chea, Maria Karkanitsa, Sokunthea Sreng, Huy Rekol, Char Meng Chour, Dominic Esposito, Jeffery K Taubenberger, Matthew J Memoli, Kaitlyn Sadtler, Patrick E Duffy, Fabiano Oliveira

Journal: medrxiv

PubMed ID: 34611671

Doi: 10.1101/2021.09.27.21264000

Products & Services: Proteins, Expression, Isolation and Analysis

Analytical and clinical performance of cPass neutralizing antibodies assay

Authors: Joanna Jung, Deepthi Rajapakshe, Christopher Julien, Sridevi Devaraj

Journal: Clin Biochem

PubMed ID: 34560062

Doi: 10.1016/j.clinbiochem.2021.09.008

Products & Services: Proteins, Expression, Isolation and Analysis

Kinase-Catalyzed Biotinylation to Map Cell Signaling Pathways: Application to Epidermal Growth Factor Signaling

Authors: Vindya Ramanayake-Mudiyanselage, D Maheeka Embogama, Mary Kay H Pflum

Journal: J Proteome Res

PubMed ID: 34491762

Doi: 10.1021/acs.jproteome.1c00562

Products & Services: Proteins, Expression, Isolation and Analysis

A Small Cysteine-Rich Phytotoxic Protein of Functions as Both Plant Defense Elicitor and Virulence Factor

Authors: Zi-Hui Zhang, Jing-Hao Jin, Gui-Lin Sheng, Yu-Ping Xing, Wang Liu, Xue Zhou, Yi-Qing Liu, Xiao-Ren Chen

Journal: Mol Plant Microbe Interact

PubMed ID: 33819070

Doi: 10.1094/MPMI-01-21-0025-R

Products & Services: Proteins, Expression, Isolation and Analysis

A Closer Look into FDA-EUA Approved Diagnostic Techniques of Covid-19

Authors: Hyunju Oh, Hyunjeong Ahn, Anubhav Tripathi

Journal: ACS Infect Dis

PubMed ID: 34569778

Doi: 10.1021/acsinfecdis.1c00268

Products & Services: Proteins, Expression, Isolation and Analysis

Consumption of gossypol increases fatty acid-amino acid conjugates in the cotton pests Helicoverpa armigera and Heliothis virescens

Authors: Corinna Krempl, Nicole Joußen, Michael Reichelt, Marco Kai, Heiko Vogel, David G Heckel

Journal: Arch Insect Biochem Physiol

PubMed ID: 34490676

Doi: 10.1002/arch.21843

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a nanobody-based competitive ELISA for efficiently and specifically detecting antibodies against genotype 2 porcine reproductive and respiratory syndrome viruses

Authors: Hong Duan, Xu Chen, Jiakai Zhao, Jiahong Zhu, Guixi Zhang, Mengnan Fan, Beibei Zhang, Xueting Wang, Yani Sun, Baoyuan Liu, En-Min Zhou, Qin Zhao

Journal: J Clin Microbiol

PubMed ID: 34524888

Doi: 10.1128/JCM.01580-21

Products & Services: DNA Sequencing

The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs

Authors: Lung-Yu Liang, Michael Roy, Christopher R Horne, Jarrod J Sandow, Minglyanna Surudoi, Laura F Dagley, Samuel N Young, Toby Dite, Jeffrey J Babon, Peter W Janes, Onisha Patel, James M Murphy, Isabelle S Lucet

Journal: Biochem J

PubMed ID: 34431498

Doi: 10.1042/BCJ20210572

Products & Services: DNA Sequencing

Genic male sterility increases rice drought tolerance

Authors: Jianyu Wen, Yafei Zeng, Yunping Chen, Fengfeng Fan, Shaoqing Li

Journal: Plant Sci

PubMed ID: 34620451

Doi: 10.1016/j.plantsci.2021.111057

Products & Services: Custom Vector Construction

Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Authors: Jonas Persson, Emmi Puuvuori, Bo Zhang, Irina Velikyan, Ola Åberg, Malin Müller, Per-Åke Nygren, Stefan Ståhl, Olle Korsgren, Olof Eriksson, John Löfblom

Journal: Sci Rep

PubMed ID: 34580321

Doi: 10.1038/s41598-021-97694-6

Products & Services: Custom Vector Construction

Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants

Authors: Tingting Li, Wenhui Xue, Qingbing Zheng, Shuo Song, Chuanlai Yang, Hualong Xiong, Sibo Zhang, Minqing Hong, Yali Zhang, Hai Yu, Yuyun Zhang, Hui Sun, Yang Huang, Tingting Deng, Xin Chi, Jinjin Li, Shaojuan Wang, Lizhi Zhou, Tingting Chen, Yingbin Wang, Tong Cheng, Tianying Zhang, Quan Yuan, Qinjian Zhao, Jun Zhang, Jason S McLellan, Z Hong Zhou, Zheng Zhang, Shaowei Li, Ying Gu, Ningshao Xia

Journal: Nat Commun

PubMed ID: 34580306

Doi: 10.1038/s41467-021-25997-3

Products & Services: Custom Vector Construction

Diffusion of a disordered protein on its folded ligand

Authors: Felix Wiggers, Samuel Wohl, Artem Dubovetskyi, Gabriel Rosenblum, Wenwei Zheng, Hagen Hofmann

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34504002

Doi: 10.1073/pnas.2106690118

Products & Services: Custom Vector Construction

Sorting nexin 6 interacts with Cullin3 and regulates programmed death ligand 1 expression

Authors: Chinmoy Ghosh, Yanli Xing, Suhua Li, Rosalie G Hoyle, Ming Sun, Jiong Li, Yue Sun

Journal: FEBS Lett

PubMed ID: 34510437

Doi: 10.1002/1873-3468.14191

Products & Services: Custom Vector Construction

Pathways of thymidine hypermodification

Authors: Yan-Jiun Lee, Nan Dai, Stephanie I Müller, Chudi Guan, Mackenzie J Parker, Morgan E Fraser, Shannon E Walsh, Janani Sridar, Andrew Mulholland, Krutika Nayak, Zhiyi Sun, Yu-Cheng Lin, Donald G Comb, Katherine Marks, Reyaz Gonzalez, Daniel P Dowling, Vahe Bandarian, Lana Saleh, Ivan R Corrêa, Peter R Weigele

Journal: Nucleic Acids Res

PubMed ID: 34522950

Doi: 10.1093/nar/gkab781

Products & Services: Codon Optimization

A Novel Miniature CRISPR-Cas13 System for SARS-CoV-2 Diagnostics

Authors: Ahmed Mahas, Qiaochu Wang, Tin Marsic, Magdy M Mahfouz

Journal: ACS Synth Biol

PubMed ID: 34546709

Doi: 10.1021/acssynbio.1c00181

Products & Services: Codon Optimization

Controlling the Orientation and Viscoelasticity of Materials-Binding Peptides on Hexagonal Boron Nitride Using Fatty Acids

Authors: Nermina Brljak, Marc R Knecht, Tiffany R Walsh

Journal: J Phys Chem B

PubMed ID: 34505506

Doi: 10.1021/acs.jpcb.1c05446

Products & Services: Catalog Peptides

In-yeast reconstruction of the African swine fever virus genome isolated from clinical samples

Authors: Fabien Labroussaa, Kemal Mehinagic, Valentina Cippa, Matthias Liniger, Hatice Akarsu, Nicolas Ruggli, Joerg Jores

Journal: STAR Protoc

PubMed ID: 34527959

Doi: 10.1016/j.xpro.2021.100803

Products & Services: Recombinant Proteins

Serological Testing Reveals the Hidden COVID-19 Burden among Health Care Workers Experiencing a SARS-CoV-2 Nosocomial Outbreak

Authors: Yu Nakagama, Yuko Komase, Katherine Candray, Sachie Nakagama, Fumiaki Sano, Tomoya Tsuchida, Hiroyuki Kunishima, Takumi Imai, Ayumi Shintani, Yuko Nitahara, Natsuko Kaku, Yasutoshi Kido

Journal: Microbiol Spectr

PubMed ID: 34550021

Doi: 10.1128/Spectrum.01082-21

Products & Services: Catalog Antibody

Hybrid fusion protein as a dual protease inhibitor for the healing of chronic wounds

Authors: Graham Strauss, Piyush Koria

Journal: Biotechnol Prog

PubMed ID: 34486249

Doi: 10.1002/btpr.3209

Products & Services: Gene Synthesis

Interferon-λ Improves the Efficacy of Intranasally or Rectally Administered Influenza Subunit Vaccines by a Thymic Stromal Lymphopoietin-Dependent Mechanism

Authors: Liang Ye, Daniel Schnepf, Annette Ohnemus, Li Ching Ong, Hans Henrik Gad, Rune Hartmann, Nils Lycke, Peter Staeheli

Journal: Front Immunol

PubMed ID: 34659250

Doi: 10.3389/fimmu.2021.749325

Products & Services: Peptide Synthesis

Coiled coil exposure and histidine tags drive function of an intracellular protein drug carrier

Authors: Anshul Dhankher, Wei Lv, William T Studstill, Julie A Champion

Journal: J Control Release

PubMed ID: 34563592

Doi: 10.1016/j.jconrel.2021.09.026

Products & Services: Gene Synthesis

Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts

Authors: Yi Yu, Lishan Jiang, Jingwen Li, Lang Lei, Houxuan Li

Journal: J Periodontol

PubMed ID: 34585393

Doi: 10.1002/JPER.21-0227

Products & Services: Custom DNA/RNA Oligos

Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs

Authors: Jesús Horacio Lara-Puente, Juan Manuel Carreño, Weina Sun, Alejandro Suárez-Martínez, Luis Ramírez-Martínez, Francisco Quezada-Monroy, Georgina Paz-De la Rosa, Rosalía Vigueras-Moreno, Gagandeep Singh, Oscar Rojas-Martínez, Héctor Elías Chagoya-Cortés, David Sarfati-Mizrahi, Ernesto Soto-Priante, Constantino López-Macías, Florian Krammer, Felipa Castro-Peralta, Peter Palese, Adolfo García-Sastre, Bernardo Lozano-Dubernard

Journal: MBio

PubMed ID: 34544278

Doi: 10.1128/mBio.01908-21

Products & Services: Gene Synthesis

Structural Characterization of the RNA-Binding Protein SERBP1 Reveals Intrinsic Disorder and Atypical RNA Binding Modes

Authors: Antoine Baudin, Alma K Moreno-Romero, Xiaoping Xu, Emily E Selig, Luiz O F Penalva, David S Libich

Journal: Front Mol Biosci

PubMed ID: 34631798

Doi: 10.3389/fmolb.2021.744707

Products & Services: Peptide Synthesis

Post-transcriptional screen of cancer amplified genes identifies ERBB2/Her2 signaling as AU-rich mRNA stability-promoting pathway

Authors: Jenan Al-Matouq, Latifa Al-Haj, Maher Al-Saif, Khalid S A Khabar

Journal: Oncogenesis

PubMed ID: 34535639

Doi: 10.1038/s41389-021-00351-w

Products & Services: Polyclonal Antibody Services

Deletion of type VIII collagen reduces blood pressure, increases carotid artery functional distensibility and promotes elastin deposition

Authors: Amanda L Mohabeer, Jeffrey T Kroetsch, Meghan McFadden, Negin Khosraviani, Thomas J Broekelmann, Guangpei Hou, Hangjun Zhang, Yu-Qing Zhou, Minyao Wang, Anthony O Gramolini, Robert P Mecham, Scott P Heximer, Steffen-Sebastian Bolz, Michelle P Bendeck

Journal: Matrix Biol Plus

PubMed ID: 34693248

Doi: 10.1016/j.mbplus.2021.100085

Products & Services: Plasmid DNA Preparation

ReScribe: An Unrestrained Tool Combining Multiplex Recombineering and Minimal-PAM ScCas9 for Genome Recoding

Authors: Enrique Asin-Garcia, Maria Martin-Pascual, Luis Garcia-Morales, Richard van Kranenburg, Vitor A P Martins Dos Santos

Journal: ACS Synth Biol

PubMed ID: 34547891

Doi: 10.1021/acssynbio.1c00297

Products & Services: Plasmid DNA Preparation

MicroRNA-361 reduces the viability and migratory ability of pancreatic cancer cells via mediation of the MAPK/JNK pathway

Authors: Juan Wang, Zongjing Xie, Yan Liu, Weiguo Zhang, Tingting Ji

Journal: Exp Ther Med

PubMed ID: 34659511

Doi: 10.3892/etm.2021.10799

Products & Services: Plasmid DNA Preparation

Yeast Translational Activator Mss51p and Human ZMYND17 - Two Proteins with a Common Origin, but Different Functions

Authors: Maria V Baleva, Uliyana E Piunova, Ivan V Chicherin, Darya G Krasavina, Sergey A Levitskii, Piotr A Kamenski

Journal: Biochemistry (Mosc)

PubMed ID: 34565318

Doi: 10.1134/S0006297921090108

Products & Services: Plasmid DNA Preparation

Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase

Authors: Xida Zhao, Jingbo Liu, Chong Zhang, Ning Yu, Ze Lu, Shuwei Zhang, Yuchao Li, Qian Li, Junchao Liu, Dongjuan Liu, Yaping Pan

Journal: Int J Oral Sci

PubMed ID: 34593756

Doi: 10.1038/s41368-021-00136-2

Products & Services: Plasmid DNA Preparation

CLE14 functions as a "brake signal" to suppress age-dependent and stress-induced leaf senescence by promoting JUB1-mediated ROS scavenging in Arabidopsis

Authors: Zenglin Zhang, Cheng Liu, Kui Li, Xiaoxu Li, Mengmeng Xu, Yongfeng Guo

Journal: Mol Plant

PubMed ID: 34530165

Doi: 10.1016/j.molp.2021.09.006

Products & Services: Peptide Synthesis

Enhancing Antigen Presentation and Inducing Antigen-Specific Immune Tolerance with Amphiphilic Peptides

Authors: Meng Li, Arata Itoh, Jingchao Xi, Chunsong Yu, Yuehong Wu, William M Ridgway, Haipeng Liu

Journal: J Immunol

PubMed ID: 34526376

Doi: 10.4049/jimmunol.1901301

Products & Services: Peptide Synthesis

Characterization of HLA-A*02:01 MHC Immunopeptide Antigens Enhanced by Ultraviolet Photodissociation Mass Spectrometry

Authors: Eleanor Watts, Gregory K Potts, Damien B Ready, Alayna M George Thompson, Janice Lee, Edwin E Escobar, Melanie J Patterson, Jennifer S Brodbelt

Journal: Anal Chem

PubMed ID: 34553926

Doi: 10.1021/acs.analchem.1c01002

Products & Services: Peptide Synthesis

Metformin inhibits hepatocellular carcinoma development by inducing apoptosis and pyroptosis through regulating FOXO3

Authors: Zetian Shen, Han Zhou, Aomei Li, Tiancong Wu, Xiaoqin Ji, Lei Guo, Xixu Zhu, Dagan Zhang, Xia He

Journal: Aging (Albany NY)

PubMed ID: 34546972

Doi: 10.18632/aging.203464

Products & Services: PCR Cloning and Subcloning

Bioinformatics Analysis of a Functional ANGPT1 Variant That Interferes with miR-607 and Its Association with Susceptibility and Outcome of Ischemic Stroke in a Han Population

Authors: Ai-Nian Chen, Ling-Ling Zhong, Ke-Ju Ju, Hua Cao

Journal: Ther Clin Risk Manag

PubMed ID: 34611404

Doi: 10.2147/TCRM.S328964

Products & Services: PCR Cloning and Subcloning

A Single Dose of a Hybrid hAdV5-Based Anti-COVID-19 Vaccine Induces a Long-Lasting Immune Response and Broad Coverage against VOC

Authors: M Verónica López, Sabrina E Vinzón, Eduardo G A Cafferata, Felipe J Núñez, Ariadna Soto, Maximiliano Sanchez-Lamas, M Jimena Afonso, Diana Aguilar-Cortes, Gregorio D Ríos, Juliana T Maricato, Carla T Braconi, Vanessa B Silveira, Tatiane M Andrad, Tatiana C S Bonetti, Luiz M Ramos Janini, Manoel J B C Girão, Andrea S Llera, Karina A Gomez, Hugo H Ortega, Paula M Berguer, Osvaldo L Podhajcer

Journal: Vaccines (Basel)

PubMed ID: 34696219

Doi: 10.3390/vaccines9101106

Products & Services: PCR Cloning and Subcloning

ORF3a Protein of Severe Acute Respiratory Syndrome Coronavirus 2 Inhibits Interferon-Activated Janus Kinase/Signal Transducer and Activator of Transcription Signaling Elevating Suppressor of Cytokine Signaling 1

Authors: Rong Wang, Xiaofeng Yang, Mingke Chang, Ziyang Xue, Weirong Wang, Liang Bai, Sihai Zhao, Enqi Liu

Journal: Front Microbiol

PubMed ID: 34650546

Doi: 10.3389/fmicb.2021.752597

Products & Services: ORF cDNA Clones/MolecularCloud

Plant Viral Nanoparticle Conjugated with Anti-PD-1 Peptide for Ovarian Cancer Immunotherapy

Authors: Aayushma Gautam, Veronique Beiss, Chao Wang, Lu Wang, Nicole F Steinmetz

Journal: Int J Mol Sci

PubMed ID: 34575893

Doi: 10.3390/ijms22189733

Products & Services: ORF cDNA Clones/MolecularCloud

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