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页码: 172/1047 每页显示数量
Mucosal immune response in BNT162b2 COVID-19 vaccine recipients
Authors: Lorenzo Azzi, Daniela Dalla Gasperina, Giovanni Veronesi, Mariam Shallak, Giuseppe Ietto, Domenico Iovino, Andreina Baj, Francesco Gianfagna, Vittorio Maurino, Daniele Focosi, Fabrizio Maggi, Marco Mario Ferrario, Francesco Dentali, Giulio Carcano, Angelo Tagliabue, Lorenzo Stefano Maffioli, Roberto Sergio Accolla, Greta Forlani
Journal: EBioMedicine
PubMed ID: 34954658
Doi: 10.1016/j.ebiom.2021.103788
Products & Services: Protein and Antibody Reagents   
Efficient discovery of potential inhibitors for SARS-CoV-2 3C-like protease from herbal extracts using a native MS-based affinity-selection method
Authors: Dafu Zhu, Haixia Su, Changqiang Ke, Chunping Tang, Matthias Witt, Ronald J Quinn, Yechun Xu, Jia Liu, Yang Ye
Journal: J Pharm Biomed Anal
PubMed ID: 34929567
Doi: 10.1016/j.jpba.2021.114538
Products & Services: Protein and Antibody Reagents   
Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells
Authors: Alissa D Guarnaccia, April M Weissmiller, William P Tansey
Journal: STAR Protoc
PubMed ID: 34917979
Doi: 10.1016/j.xpro.2021.101000
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Sequential dynamics of virological and serological changes in the serum of SARS-CoV-2 infected patients
Authors: Serge Ouoba, Mafumi Okimoto, Shintaro Nagashima, Yoshihiro Kitahara, Kei Miwata, Ko Ko, Bunthen E, Aya Sugiyama, Kazuaki Takahashi, Takemasa Sakaguchi, Toshiro Takafuta, Junko Tanaka
Journal: J Med Virol
PubMed ID: 34897741
Doi: 10.1002/jmv.27518
Products & Services: Protein and Antibody Reagents   
Identification and validation of potential mRNA- microRNA- long-noncoding RNA (mRNA-miRNA-lncRNA) prognostic signature for cervical cancer
Authors: Jie Wang, Chen Zhang
Journal: Bioengineered
PubMed ID: 33682613
Doi: 10.1080/21655979.2021.1890377
Products & Services: Polyclonal Antibody Services   
Generation and utility of a single-chain fragment variable monoclonal antibody platform against a baculovirus expressed recombinant receptor binding domain of SARS-CoV-2 spike protein
Authors: Reda Salem, Alaa A El-Kholy, Fatma R Waly, Dalia Ayman, Aya Sakr, Mai Hussein
Journal: Mol Immunol
PubMed ID: 34915268
Doi: 10.1016/j.molimm.2021.12.006
Products & Services: Codon Optimization   
Deep mutational scanning for therapeutic antibody engineering
Authors: Kyrin R Hanning, Mason Minot, Annmaree K Warrender, William Kelton, Sai T Reddy
Journal: Trends Pharmacol Sci
PubMed ID: 34895944
Doi: 10.1016/j.tips.2021.11.010
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An engineered oncolytic vaccinia virus encoding a single-chain variable fragment against TIGIT induces effective antitumor immunity and synergizes with PD-1 or LAG-3 blockade
Authors: Shuguang Zuo, Min Wei, Tiancheng Xu, Lingkai Kong, Bohao He, Shiqun Wang, Shibing Wang, Junhua Wu, Jie Dong, Jiwu Wei
Journal: J Immunother Cancer
PubMed ID: 34949694
Doi: 10.1136/jitc-2021-002843
Products & Services: Gene Fragments   
Cryopreservation of network bioactivity and multi-lineage stromal cell differentiation potential within three-dimensional synthetic hydrogels
Authors:
Journal: Cryobiology
PubMed ID: 34922883
Doi: 10.1016/j.cryobiol.2021.12.003
Products & Services: Molecular Biology Reagents   
COVID-19 mRNA booster vaccines elicit strong protection against SARS-CoV-2 Omicron variant in patients with cancer
Authors: Cong Zeng, John P Evans, Karthik Chakravarthy, Panke Qu, Sarah Reisinger, No-Joon Song, Mark P Rubinstein, Peter G Shields, Zihai Li, Shan-Lu Liu
Journal: Cancer Cell
PubMed ID: 34986328
Doi: 10.1016/j.ccell.2021.12.014
Products & Services: PCR Cloning and Subcloning   
Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells
Authors: Mark J Turner, Yukiko Sato, David Y Thomas, Kathy Abbott-Banner, John W Hanrahan
Journal: Cell Physiol Biochem
PubMed ID: 34936285
Doi: 10.33594/000000477
Products & Services: Protein and Antibody Isolation   
Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells
Authors: Mark J Turner, Yukiko Sato, David Y Thomas, Kathy Abbott-Banner, John W Hanrahan
Journal: Cell Physiol Biochem
PubMed ID: 34936285
Doi: 10.33594/000000477
Products & Services: Protein and Antibody Isolation   
MiR-31 targets HSD17B14 and FSHR, and miR-20b targets HSD17B14 to affect apoptosis and steroid hormone metabolism of porcine ovarian granulosa cells
Authors: Siyuan Gao, Jing Zhao, Qinglei Xu, Yanli Guo, Mingzheng Liu, Chunlei Zhang, Allan P Schinckel, Bo Zhou
Journal: Theriogenology
PubMed ID: 34959084
Doi: 10.1016/j.theriogenology.2021.12.014
Products & Services: Protein and Antibody Isolation   
Structural Insight into the Mechanism of PALB2 Interaction with MRG15
Authors: Jennifer Redington, Jaigeeth Deveryshetty, Lakshmi Kanikkannan, Ian Miller, Sergey Korolev
Journal: Genes (Basel)
PubMed ID: 34946951
Doi: 10.3390/genes12122002
Products & Services: Mutant Libraries   
The impact of benzo[a]pyrene on murine allergic airway inflammation via epigenetic remodeling
Authors: Xihua Wang, Shuyuan Guan, Lingbin Sun, Zhongliang Dai
Journal: Environ Toxicol Pharmacol
PubMed ID: 34883242
Doi: 10.1016/j.etap.2021.103782
Products & Services: Protein and Antibody Isolation   
A metabolic labeling protocol to enrich myristoylated proteins from
Authors: Xin Gong, Yanwen Feng, Hongyun Tang
Journal: STAR Protoc
PubMed ID: 34917984
Doi: 10.1016/j.xpro.2021.101013
Products & Services: Protein and Antibody Isolation   
Adenovirus-mediated RNA interference against herpes simplex virus infection in vitro
Authors: Lin Chen, Zhi-Qiang Pan, Chang-Bin Zhai
Journal: Folia Histochem Cytobiol
PubMed ID: 34905214
Doi: 10.5603/FHC.a2021.0031
Products & Services: Gene Fragments   
BIX-01294 enhances the effect of chemotherapy on colorectal cancer by inhibiting the expression of stemness genes
Authors: Shikang Liu, Yihang Jiang, Hua Yang, Zhongke Hua, Yu Han, Cai Zhou, Shuling Xu, Shenglan Nie, Gaixia Xu, Xingsheng Shu, Xiaomei Wang
Journal: Biochem Biophys Res Commun
PubMed ID: 34979318
Doi: 10.1016/j.bbrc.2021.12.089
Products & Services: Recombinant Proteins   
Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2
Authors: Lihong Liu, Sho Iketani, Yicheng Guo, Jasper F-W Chan, Maple Wang, Liyuan Liu, Yang Luo, Hin Chu, Yiming Huang, Manoj S Nair, Jian Yu, Kenn K-H Chik, Terrence T-T Yuen, Chaemin Yoon, Kelvin K-W To, Honglin Chen, Michael T Yin, Magdalena E Sobieszczyk, Yaoxing Huang, Harris H Wang, Zizhang Sheng, Kwok-Yung Yuen, David D Ho
Journal: Nature
PubMed ID: 35016198
Doi: 10.1038/s41586-021-04388-0
Products & Services: Catalog Antibodies   
A unique NLRC4 receptor from echinoderms mediates Vibrio phagocytosis via rearrangement of the cytoskeleton and polymerization of F-actin
Authors: Kaiyu Chen, Siyuan Zhang, Yina Shao, Ming Guo, Weiwei Zhang, Chenghua Li
Journal: PLoS Pathog
PubMed ID: 34898657
Doi: 10.1371/journal.ppat.1010145
Products & Services: Recombinant Antibody Expression   
A unique NLRC4 receptor from echinoderms mediates Vibrio phagocytosis via rearrangement of the cytoskeleton and polymerization of F-actin
Authors: Kaiyu Chen, Siyuan Zhang, Yina Shao, Ming Guo, Weiwei Zhang, Chenghua Li
Journal: PLoS Pathog
PubMed ID: 34898657
Doi: 10.1371/journal.ppat.1010145
Products & Services: Recombinant Antibody Expression   
Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men
Authors: Nina Le Bert, Wan Ni Chia, Wei Yee Wan, Alvin Kuo Jing Teo, Samuel Zeng-Rong Chong, Nicole Tan, Doreen Soek Chin Tan, Adeline Chia, Iain Beehuat Tan, Kamini Kunasegaran, Qin Xuan Chua, Mohammad Yazid Abdad, Aven Shan Hua Ng, Shawn Vasoo, Julian Xiao-Li Ang, Mao Sheng Lee, Louisa Sun, Jinyan Fang, Feng Zhu, Alex R Cook, Tar Choon Aw, Jingxiang Huang, Clarence Tam, Fong Sin Lee, Hannah Clapham, Enan Jun-Kang Goh, Monica Socheata Suor Peou, Shiow Pin Tan, Siew Kim Ong, Lin-Fa Wang, Antonio Bertoletti, Li Yang Hsu, Biauw Chi Ong
Journal: Emerg Microbes Infect
PubMed ID: 34709140
Doi: 10.1080/22221751.2021.1999777
Safety evaluation of the mouse TCRα - transduced T cell product in preclinical models in vivo and in vitro
Authors: Anastasiia Kalinina, Alexandra Bruter, Nadezhda Persiyantseva, Yulia Silaeva, Maria Zamkova, Ludmila Khromykh, Dmitry Kazansky
Journal: Biomed Pharmacother
PubMed ID: 34915667
Doi: 10.1016/j.biopha.2021.112480
Products & Services: Molecular Biology Reagents   
A Pathogen-Inducible Rice NAC Transcription Factor ONAC096 Contributes to Immunity Against and pv by Direct Binding to the Promoters of , Magnaprothe oryzae, and Xanthomonas oryzaeoryzae OsRap26 OsWRKY62 OsPAL1
Authors: Hui Wang, Yan Bi, Yizhou Gao, Yuqing Yan, Xi Yuan, Xiaohui Xiong, Jiajing Wang, Jiayu Liang, Dayong Li, Fengming Song
Journal: Front Plant Sci
PubMed ID: 34956298
Doi: 10.3389/fpls.2021.802758
Products & Services: Catalog Peptides   
Nanopore-based measurement of the interaction of P450cam monooxygenase and putidaredoxin at the single-molecule level
Authors: Hui Chen, Yao Lin, Yi-Tao Long, Shelley D Minteer, Yi-Lun Ying
Journal: Faraday Discuss
PubMed ID: 34889330
Doi: 10.1039/d1fd00042j
Products & Services: Plasmid DNA Preparation   
Functional Characterization of Spinocerebellar Ataxia Associated Dynorphin A Mutant Peptides
Authors: Andreas Lieb, Germana Thaler, Barbara Fogli, Olga Trovato, Mitja Amon Posch, Teresa Kaserer, Luca Zangrandi
Journal: Biomedicines
PubMed ID: 34944698
Doi: 10.3390/biomedicines9121882
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Synergistic enzyme cocktail between levansucrase and inulosucrase for superb levan-type fructooligosaccharide synthesis
Authors: Karan Wangpaiboon, Methus Klaewkla, Thanapon Charoenwongpaiboon, Napas Vongkusolkit, Pawinee Panpetch, Kamontip Kuttiyawong, Wonnop Visessanguan, Rath Pichyangkura
Journal: Enzyme Microb Technol
PubMed ID: 34923315
Doi: 10.1016/j.enzmictec.2021.109960
Products & Services: Protein and Antibody Isolation   
Gastrin producing syngeneic mesenchymal stem cells protect non-obese diabetic mice from type 1 diabetes
Authors: Marie-Claude Gaudreau, Radhika R Gudi, Gongbo Li, Benjamin M Johnson, Chenthamarakshan Vasu
Journal: Autoimmunity
PubMed ID: 34882054
Doi: 10.1080/08916934.2021.2012165
Products & Services: Gene Synthesis   
Novel sequential immunocapture microflow LC/MS/MS approach to measuring PTH-Fc protein in human serum
Authors: Haixing Wang, Jiang Wu, Peng Pan, Thuy Nguyen, Michael Cwik, Ling Morgan
Journal: Bioanalysis
PubMed ID: 34894717
Doi: 10.4155/bio-2021-0233
Products & Services: Codon Optimization   
Rapid kinetics of calcium dissociation from plant calmodulin and calmodulin-like proteins and effect of target peptides
Authors: Francesca Troilo, Marco Pedretti, Carlo Travaglini-Allocatelli, Alessandra Astegno, Adele Di Matteo
Journal: Biochem Biophys Res Commun
PubMed ID: 34974297
Doi: 10.1016/j.bbrc.2021.12.077
Products & Services: Peptide Synthesis   
Modifications of IL-6 by Hypochlorous Acids: Effects on Receptor Binding
Authors: Lori I Robins, Erika K Keim, Deborah B Robins, John S Edgar, John S Meschke, Philip R Gafken, Jeffrey F Williams
Journal: ACS Omega
PubMed ID: 34984290
Doi: 10.1021/acsomega.1c05297
Products & Services: Gene Synthesis   
Low-dose cyclooxygenase-2 (COX-2) inhibitor celecoxib plays a protective role in the rat model of neonatal necrotizing enterocolitis
Authors:
Journal: Bioengineered
PubMed ID: 34546832
Doi: 10.1080/21655979.2021.1980646
Products & Services: Custom DNA/RNA Oligos   
Peptides GWN and GW protect kidney cells against Dasatinib induced mitochondrial injury in a SIRT1 dependent manner
Authors: Khushwant S Bhullar, Fatemeh Ashkar, Jianping Wu
Journal: Food Chem (Oxf)
PubMed ID: 35415678
Doi: 10.1016/j.fochms.2021.100069
Products & Services: Peptide Synthesis   
Protection against avian coronavirus conferred by oral vaccination with live bacteria secreting LTB-fused viral proteins
Authors: Avishai Lublin, Chen Katz, Nady Gruzdev, Itamar Yadid, Itai Bloch, Yigal Farnoushi, Luba Simanov, Asaf Berkowitz, Dalia Elyahu, Jacob Pitcovski, Ehud Shahar
Journal: Vaccine
PubMed ID: 34998606
Doi: 10.1016/j.vaccine.2021.12.053
Products & Services: Gene Fragments   
Microbial synthesis of 4-hydroxybenzoic acid from renewable feedstocks
Authors: Yueyang Chen, Yufen Chen, Lijun Liu, Yang Zhang, Jifeng Yuan
Journal: Food Chem (Oxf)
PubMed ID: 35415641
Doi: 10.1016/j.fochms.2021.100059
Products & Services: Gene Synthesis   
Ultrasound treatment can increase digestibility of myofibrillar protein of pork with modified atmosphere packaging
Authors: Shuai Jiang, Miao Zhang, Hui Liu, Qian Li, Dejiang Xue, Yingqun Nian, Di Zhao, Kai Shan, Chen Dai, Chunbao Li
Journal: Food Chem
PubMed ID: 35030336
Doi: 10.1016/j.foodchem.2021.131811
Products & Services: Protein and Antibody Isolation   
4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase
Authors: Emma G Jackson, Giuliano Cutolo, Bo Yang, Nageswari Yarravarapu, Mary W N Burns, Ganka Bineva-Todd, Chloë Roustan, James B Thoden, Halley M Lin-Jones, Toin H van Kuppevelt, Hazel M Holden, Benjamin Schumann, Jennifer J Kohler, Christina M Woo, Matthew R Pratt
Journal: ACS Chem Biol
PubMed ID: 34931806
Doi: 10.1021/acschembio.1c00818
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Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors
Authors: Tamara Muliaditan, Leena Halim, Lynsey M Whilding, Benjamin Draper, Daniela Y Achkova, Fahima Kausar, Maya Glover, Natasha Bechman, Appitha Arulappu, Jenifer Sanchez, Katie R Flaherty, Jana Obajdin, Kristiana Grigoriadis, Pierre Antoine, Daniel Larcombe-Young, Caroline M Hull, Richard Buus, Peter Gordon, Anita Grigoriadis, David M Davies, Anna Schurich, John Maher
Journal: Cell Rep Med
PubMed ID: 35028604
Doi: 10.1016/j.xcrm.2021.100457
Products & Services: Gene Synthesis   
Indoleamine 2, 3 Dioxygenase 1 Impairs Chondrogenic Differentiation of Mesenchymal Stem Cells in the Joint of Osteoarthritis Mice Model
Authors: Murad Alahdal, Rongxiang Huang, Li Duan, Deng Zhiqin, Ouyang Hongwei, Wencui Li, Daping Wang
Journal: Front Immunol
PubMed ID: 34956209
Doi: 10.3389/fimmu.2021.781185
Products & Services: Protein and Antibody Isolation   
SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells
Authors: Jinliang Wang, Guan Yang, Xinxin Wang, Zhiyuan Wen, Lei Shuai, Jie Luo, Chong Wang, Ziruo Sun, Renqiang Liu, Jinying Ge, Xijun He, Ronghong Hua, Xijun Wang, Xiao Yang, Weiye Chen, Gongxun Zhong, Zhigao Bu
Journal: Cell Discov
PubMed ID: 34903715
Doi: 10.1038/s41421-021-00357-z
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SARS-CoV-2 N Protein Induces Acute Lung Injury in Mice NF-ĸB Activation
Authors: Jie Xia, Wenqi Tang, Jiangmei Wang, Dengming Lai, Qi Xu, Ruoqiong Huang, Yaoqin Hu, Xiaojue Gong, Jiajie Fan, Qiang Shu, Jianguo Xu
Journal: Front Immunol
PubMed ID: 34950152
Doi: 10.3389/fimmu.2021.791753
Products & Services: Protein and Antibody Isolation   
SARS-CoV-2 seroprevalence, seroconversion and neutralizing antibodies in a systemic lupus erythematosus cohort and comparison to controls
Authors: Hannah R Mathew, May Y Choi, Katherine Buhler, Xenia Gukova, Francesca S Cardwell, Heather Waldhauser, Ann E Clarke, Marvin J Fritzler
Journal: Lupus
PubMed ID: 34874781
Doi: 10.1177/09612033211063793
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Engineering a Pseudo-26-kDa Glutathione Transferase from / for Structure, Kinetics, and Ligandin Studies
Authors: Neo Padi, Blessing Oluebube Akumadu, Olga Faerch, Chinyere Aloke, Vanessa Meyer, Ikechukwu Achilonu
Journal: Biomolecules
PubMed ID: 34944488
Doi: 10.3390/biom11121844
Products & Services: PCR Cloning and Subcloning   
Novel pentose-regulated promoter of with application in controlling heterologous gene expression
Authors: Sukanya Jeennor, Jutamas Anantayanon, Chanikul Chutrakul, Sarocha Panchanawaporn, Kobkul Laoteng
Journal: Biotechnol Rep (Amst)
PubMed ID: 35004236
Doi: 10.1016/j.btre.2021.e00695
Products & Services: Gene Synthesis   
pH Low Insertion Peptide-Modified Programmed Cell Death-Ligand 1 Potently Suppresses T-Cell Activation Under Acidic Condition
Authors: Ying Sun, Linhan Hu, Peng Yang, Min Zhang, Xinwei Wang, He Xiao, Chunxia Qiao, Jing Wang, Longlong Luo, Jiannan Feng, Yuanqiang Zheng, Yi Wang, Yanchun Shi, Guojiang Chen
Journal: Front Immunol
PubMed ID: 35003115
Doi: 10.3389/fimmu.2021.794226
Products & Services: Recombinant Antibody Expression   
Construction, Investigation and Application of TEV Protease Variants with Improved Oxidative Stability
Authors: Enkhtuya Bayar, Yuanyuan Ren, Yinghua Chen, Yafang Hu, Shuncheng Zhang, Xuelian Yu, Jun Fan
Journal: J Microbiol Biotechnol
PubMed ID: 34528919
Doi: 10.4014/jmb.2106.06075
Products & Services: Plasmid DNA Preparation   
Overproduction of medicinal ergot alkaloids based on a fungal platform
Authors: Yongpeng Yao, Wei Wang, Wenyu Shi, Rui Yan, Jun Zhang, Guangzheng Wei, Ling Liu, Yongsheng Che, Chunyan An, Shu-Shan Gao
Journal: Metab Eng
PubMed ID: 34902590
Doi: 10.1016/j.ymben.2021.12.002
Products & Services: Gene Synthesis   
Comprehensive Analysis and Biological Characterization of Venom Components from Solitary Scoliid Wasp
Authors: Carlos Alberto-Silva, Fernanda Calheta Vieira Portaro, Roberto Tadashi Kodama, Halyne Queiroz Pantaleão, Hidetoshi Inagaki, Ken-Ichi Nihei, Katsuhiro Konno
Journal: Toxins (Basel)
PubMed ID: 34941722
Doi: 10.3390/toxins13120885
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A vesicular stomatitis virus-based prime-boost vaccination strategy induces potent and protective neutralizing antibodies against SARS-CoV-2
Authors: Gyoung Nyoun Kim, Jung-Ah Choi, Kunyu Wu, Nasrin Saeedian, Eunji Yang, Hayan Park, Sun-Je Woo, Gippeum Lim, Seong-Gyu Kim, Su-Kyeong Eo, Hoe Won Jeong, Taewoo Kim, Jae-Hyung Chang, Sang Hwan Seo, Na Hyung Kim, Eunsil Choi, Seungho Choo, Sangkyun Lee, Andrew Winterborn, Yue Li, Kate Parham, Justin M Donovan, Brock Fenton, Jimmy D Dikeakos, Gregory A Dekaban, S M Mansour Haeryfar, Ryan M Troyer, Eric J Arts, Stephen D Barr, Manki Song, C Yong Kang
Journal: PLoS Pathog
PubMed ID: 34914812
Doi: 10.1371/journal.ppat.1010092
Products & Services: Mammalian Expression   
HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma
Authors: Benjy Jy Tan, Kenji Sugata, Omnia Reda, Misaki Matsuo, Kyosuke Uchiyama, Paola Miyazato, Vincent Hahaut, Makoto Yamagishi, Kaoru Uchimaru, Yutaka Suzuki, Takamasa Ueno, Hitoshi Suzushima, Hiroo Katsuya, Masahito Tokunaga, Yoshikazu Uchiyama, Hideaki Nakamura, Eisaburo Sueoka, Atae Utsunomiya, Masahiro Ono, Yorifumi Satou
Journal: J Clin Invest
PubMed ID: 34907908
Doi: 10.1172/JCI150472
Products & Services: Catalog Peptides   
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