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页码: 166/1028 每页显示数量

Characterization and Inhibition of 1-Deoxy-d-Xylulose 5-Phosphate Reductoisomerase: A Promising Drug Target in and

Authors: Haley S Ball, Misgina B Girma, Mosufa Zainab, Iswarduth Soojhawon, Robin D Couch, Schroeder M Noble

Journal: ACS Infect Dis

PubMed ID: 34672535

Doi: 10.1021/acsinfecdis.1c00132

Products & Services: Custom Vector Construction

Bacterial Quorum-Quenching Lactonase Hydrolyzes Fungal Mycotoxin and Reduces Pathogenicity of -Suggesting a Mechanism of Bacterial Antagonism

Authors: Shlomit Dor, Dov Prusky, Livnat Afriat-Jurnou

Journal: J Fungi (Basel)

PubMed ID: 34682247

Doi: 10.3390/jof7100826

Products & Services: Custom Vector Construction

Strongly Hydrogen-Bonded Schiff Base and Adjoining Polyene Twisting in the Retinal Chromophore of Schizorhodopsins

Authors: Tomomi Shionoya, Manish Singh, Misao Mizuno, Hideki Kandori, Yasuhisa Mizutani

Journal: Biochemistry

PubMed ID: 34601881

Doi: 10.1021/acs.biochem.1c00529

Products & Services: Codon Optimization

A Thermostable Cas12b from Leverages One-pot Detection of SARS-CoV-2 Variants of Concern

Authors: Long T Nguyen, Nicolas C Macaluso, Brianna L M Pizzano, Melanie N Cash, Jan Spacek, Jan Karasek, Rhoel R Dinglasan, Marco Salemi, Piyush K Jain

Journal: medrxiv

PubMed ID: 34704101

Doi: 10.1101/2021.10.15.21265066

Products & Services: Codon Optimization

Homocysteine Inhibits Pro-Insulin Receptor Cleavage and Causes Insulin Resistance Via Protein Cysteine-Homocysteinylation

Authors: Xuan Zhang, Yuan-Yuan Qu, Lian Liu, Ya-Nan Qiao, Hao-Ran Geng, Yan Lin, Wei Xu, Jing Cao, Jian-Yuan Zhao

Journal: Cell Rep

PubMed ID: 34644569

Doi: 10.2139/ssrn.3830772

Products & Services: Goat Anti-Mouse IgG Antibody (H&L) [HRP], pAb

Identification and Characterization of a Novel Epitope of ASFV-Encoded dUTPase by Monoclonal Antibodies

Authors: Shuai Zhang, Rui Wang, Xiaojing Zhu, Jiaxin Jin, Wenlong Lu, Xuyang Zhao, Bo Wan, Yifei Liao, Qin Zhao, Christopher L Netherton, Guoqing Zhuang, Aijun Sun, Gaiping Zhang

Journal: Viruses

PubMed ID: 34834981

Doi: 10.3390/v13112175

Products & Services: Peptide Synthesis

Pathogenic Mechanism of Der p 38 as a Novel Allergen Homologous to RipA and RipB Proteins in Atopic Dermatitis

Authors: Hyang Jeon, Geunyeong Kim, Ayesha Kashif, Min Hwa Hong, Ji-Sook Lee, Yujin Hong, Beom Seok Park, Eun Ju Yang, In Sik Kim

Journal: Front Immunol

PubMed ID: 34691014

Doi: 10.3389/fimmu.2021.646316

Products & Services: Endotoxin Detection & Removal System

The S Protein of Group B Is a Critical Virulence Determinant That Impacts the Cell Surface Virulome

Authors: Anaamika Campeau, Satoshi Uchiyama, Concepcion Sanchez, Consuelo Sauceda, Victor Nizet, David J Gonzalez

Journal: Front Microbiol

PubMed ID: 34721327

Doi: 10.3389/fmicb.2021.729308

Products & Services: Plasmid DNA Preparation

Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas

Authors: Keren Isaev, Lingyan Jiang, Shuai Wu, Christian A Lee, Valérie Watters, Victoire Fort, Ricky Tsai, Fiona J Coutinho, Samer M I Hussein, Jie Zhang, Jinsong Wu, Peter B Dirks, Daniel Schramek, Jüri Reimand

Journal: Cell Rep

PubMed ID: 34686327

Doi: 10.1016/j.celrep.2021.109873

Products & Services: PCR Cloning and Subcloning

MYB70 modulates seed germination and root system development in

Authors: Jinpeng Wan, Ruling Wang, Ping Zhang, Liangliang Sun, Qiong Ju, Haodong Huang, Shiyou Lü, Lam-Son Tran, Jin Xu

Journal: iScience

PubMed ID: 34746697

Doi: 10.1016/j.isci.2021.103228

Products & Services: Proteins, Expression, Isolation and Analysis

Structure-Function Analysis of Resistance to Bamlanivimab by SARS-CoV-2 Variants Kappa, Delta, and Lambda

Authors: Shufeng Liu, Tien Huynh, Charles B Stauft, Tony T Wang, Binquan Luan

Journal: J Chem Inf Model

PubMed ID: 34648284

Doi: 10.1021/acs.jcim.1c01058

Products & Services: Recombinant Proteins

Effect of Cotton Leafroll Dwarf Virus on Physiological Processes and Yield of Individual Cotton Plants

Authors: Ved Parkash, Divya Bhanu Sharma, John Snider, Sudeep Bag, Phillip Roberts, Afsha Tabassum, Dalton West, Sameer Khanal, Nelson Suassuna, Peng Chee

Journal: Front Plant Sci

PubMed ID: 34659302

Doi: 10.3389/fpls.2021.734386

Products & Services: PCR and Cloning

NLRC4 inflammasome-dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice

Authors: Peipei Zhang, Yifei Liu, Lichen Hu, Kai Huang, Mao Hong, Yuze Wang, Xinrui Fan, Richard J Ulevitch, Jiahuai Han

Journal: Sci Adv

PubMed ID: 34678072

Doi: 10.1126/sciadv.abi9471

Products & Services: PCR and Cloning

An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats

Authors: Martijn A Langereis, Irina C Albulescu, Judith Stammen-Vogelzangs, Morindy Lambregts, Ken Stachura, Suzan Miller, Angela M Bosco-Lauth, Airn E Hartwig, Stephanie M Porter, Michelle Allen, Mark Mogler, Frank J M van Kuppeveld, Berend-Jan Bosch, Paul Vermeij, Ad de Groof, Richard A Bowen, Randy Davis, Zach Xu, Ian Tarpey

Journal: npj Vaccines

PubMed ID: 34671047

Doi: 10.1038/s41541-021-00390-9

Products & Services: Recombinant Proteins

Abnormal Blood Coagulation and Kidney Damage in Aged Hamsters Infected with Severe Acute Respiratory Syndrome Coronavirus 2

Authors: Marumi Ohno, Michihito Sasaki, Yasuko Orba, Toshiki Sekiya, Md Abdul Masum, Osamu Ichii, Tatsuya Sawamura, Akemi Kakino, Yasuhiko Suzuki, Hiroshi Kida, Hirofumi Sawa, Masashi Shingai

Journal: Viruses

PubMed ID: 34834944

Doi: 10.3390/v13112137

Products & Services: Codon Optimization

The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity

Authors: Kevin J Forsberg, Danica T Schmidtke, Rachel Werther, Ruben V Uribe, Deanna Hausman, Morten O A Sommer, Barry L Stoddard, Brett K Kaiser, Harmit S Malik

Journal: PLoS Biol

PubMed ID: 34644300

Doi: 10.1371/journal.pbio.3001428

Products & Services: Mutant Libraries

Kinetochore-bound Mps1 regulates kinetochore-microtubule attachments via Ndc80 phosphorylation

Authors: Krishna K Sarangapani, Lori B Koch, Christian R Nelson, Charles L Asbury, Sue Biggins

Journal: J Cell Biol

PubMed ID: 34647959

Doi: 10.1083/jcb.202106130

Products & Services: GenParts™ DNA Fragments

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis

Authors: Qianxing Zou, Lele Yang, Ruona Shi, Yuling Qi, Xiaofei Zhang, Huayu Qi

Journal: iScience

PubMed ID: 34825148

Doi: 10.1016/j.isci.2021.103396

Products & Services: Gene Synthesis

Metabolic adaptation drives arsenic trioxide resistance in acute promyelocytic leukemia

Authors: Nithya Balasundaram, Saravanan Ganesan, Ezhilarasi Chendamarai, Hamenth Kumar Palani, Arvind Venkatraman, Ansu Abu Alex, Sachin David, Swathy Palanikumar, Nair Reeshma Radhakrishnan, Mohammed Yasar M, Sanjeev Krishna, Anu Korula, Uday Kulkarni, Nancy Beryl Janet, Poonkuzhali Balasubramanian, Vikram Mathews

Journal: Blood Adv

PubMed ID: 34625794

Doi: 10.1182/bloodadvances.2021005300

Products & Services: PCR and Cloning

Evolutionary transcriptomics implicates new genes and pathways in human pregnancy and adverse pregnancy outcomes

Authors: Katelyn Mika, Mirna Marinić, Manvendra Singh, Joanne Muter, Jan Joris Brosens, Vincent J Lynch

Journal: Elife

PubMed ID: 34623259

Doi: 10.7554/eLife.69584

Products & Services: Plasmid DNA Preparation

Design of a synthesis-friendly hypoxia-responsive promoter for cell-based therapeutics

Authors: Chee Ka Candice Lam, Kevin Truong

Journal: Eng Life Sci

PubMed ID: 34899121

Doi: 10.1002/elsc.202100045

Products & Services: PCR Cloning and Subcloning

Waning humoral response 6 months after SARS-CoV-2 vaccination with the mRNA-BNT162b2 vaccine in hemodialysis patients: time for a boost

Authors: Tamara Davidovic, Judith Schimpf, Armin Abbassi-Nik, Richard Stockinger, Hannelore Sprenger-Mähr, Karl Lhotta, Emanuel Zitt

Journal: Kidney Int

PubMed ID: 34656642

Doi: 10.1016/j.kint.2021.10.006

Epitopes prediction for microcystin-LR by molecular docking

Authors: Yuan Liu, Shu Liu, Chongxin Xu, Manman Lin, Yihang Li, Cheng Shen, Ying Liang, Xing Sun, Donglan Wang, Peng Lü, Xianjin Liu

Journal: Ecotoxicol Environ Saf

PubMed ID: 34717216

Doi: 10.1016/j.ecoenv.2021.112925

Products & Services: Custom Vector Construction

Quantifying oxidation of cellulose-associated glucuronoxylan by two lytic polysaccharide monooxygenases from

Authors: Olav A Hegnar, Heidi Østby, Dejan M Petrović, Lisbeth Olsson, Anikó Várnai, Vincent G H Eijsink

Journal: Appl Environ Microbiol

PubMed ID: 34613755

Doi: 10.1128/AEM.01652-21

Products & Services: Codon Optimization

Black Phosphorus Nanoparticles Promote Osteogenic Differentiation of EMSCs Through Upregulated TG2 Expression

Authors: Naiyan Lu, Xinhe Wang, Wentao Shi, Lu Bian, Xuan Zhang, Guofeng Yang, Xue Tang, Jun Wang, Yin Zou, Yuyan Weng

Journal: Nanoscale Res Lett

PubMed ID: 34637014

Doi: 10.1186/s11671-021-03610-2

Products & Services: Custom Vector Construction

In vivo Profiling of the Alk Proximitome in the Developing Drosophila Brain

Authors: Ezgi Uçkun, Georg Wolfstetter, Vimala Anthonydhason, Sanjay Kumar Sukumar, Ganesh Umapathy, Linnea Molander, Johannes Fuchs, Ruth H Palmer

Journal: J Mol Biol

PubMed ID: 34624297

Doi: 10.1016/j.jmb.2021.167282

Products & Services: Polyclonal Antibody Services

CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis

Authors: Xiaoxun Li, Yajun Liang, Cheng Lian, Fangli Peng, Yansen Xiao, Yunfei He, Chengxin Ma, Yuan Wang, Peiyuan Zhang, Yuhan Deng, Yunpeng Su, Cheng Luo, Xiangyin Kong, Qingcheng Yang, Tong Liu, Guohong Hu

Journal: Theranostics

PubMed ID: 34815788

Doi: 10.7150/thno.62187

Products & Services: Catalog Peptides

Combining an optimized mRNA template with a double purification process allows strong expression of transcribed mRNA

Authors: Sergio Linares-Fernández, Julien Moreno, Elise Lambert, Perrine Mercier-Gouy, Laetitia Vachez, Bernard Verrier, Jean-Yves Exposito

Journal: Mol Ther Nucleic Acids

PubMed ID: 34692232

Doi: 10.1016/j.omtn.2021.10.007

Products & Services: Gene Synthesis

Identifying a Ferroptosis-Related Gene Signature for Predicting Biochemical Recurrence of Prostate Cancer

Authors: Zhengtong Lv, Jianlong Wang, Xuan Wang, Miao Mo, Guyu Tang, Haozhe Xu, Jianye Wang, Yuan Li, Ming Liu

Journal: Front Cell Dev Biol

PubMed ID: 34778244

Doi: 10.3389/fcell.2021.666025

Products & Services: Gene Synthesis

Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore

Authors: Evgeniya Trofimenko, Gianvito Grasso, Mathieu Heulot, Nadja Chevalier, Marco A Deriu, Gilles Dubuis, Yoan Arribat, Marc Serulla, Sebastien Michel, Gil Vantomme, Florine Ory, Linh Chi Dam, Julien Puyal, Francesca Amati, Anita Lüthi, Andrea Danani, Christian Widmann

Journal: Elife

PubMed ID: 34713805

Doi: 10.7554/eLife.69832

Products & Services: Plasmid DNA Preparation

Aptamer-modified biosensors to visualize neurotransmitter flux

Authors: Charlotte Moraldo, Emilie Vuille-Dit-Bille, Bajramshahe Shkodra, Tom Kloter, Nako Nakatsuka

Journal: J Neurosci Methods

PubMed ID: 34653500

Doi: 10.1016/j.jneumeth.2021.109386

Products & Services: Stable Cell Lines

Anastrozole regulates fatty acid synthase in breast cancer

Authors: Junmei Cairns, James N Ingle, Krishna R Kalari, Matthew P Goetz, Richard M Weinshilboum, Huanyao Gao, Hu Li, Mehrab Ghanat Bari, Liewei Wang

Journal: Mol Cancer Ther

PubMed ID: 34667110

Doi: 10.1158/1535-7163.MCT-21-0509

Products & Services: Mutant Libraries

Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry

Authors: Young-Jun Park, Anna De Marco, Tyler N Starr, Zhuoming Liu, Dora Pinto, Alexandra C Walls, Fabrizia Zatta, Samantha K Zepeda, John Bowen, Kaitlin S Sprouse, Anshu Joshi, Martina Giurdanella, Barbara Guarino, Julia Noack, Rana Abdelnabi, Shi-Yan Caroline Foo, Florian A Lempp, Fabio Benigni, Gyorgy Snell, Johan Neyts, Sean Pj Whelan, Herbert W Virgin, Jesse D Bloom, Davide Corti, Matteo Samuele Pizzuto, David Veesler

Journal: biorxiv

PubMed ID: 34671770

Doi: 10.1101/2021.10.13.464254

Products & Services: Gene Synthesis

Erratum: Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies

Authors:

Journal: Front Pharmacol

PubMed ID: 34744755

Doi: 10.3389/fphar.2021.788046

Products & Services: Peptide Synthesis

Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues

Authors: Sanket S Ponia, Shelly J Robertson, Kristin L McNally, Gayatri Subramanian, Gail L Sturdevant, Matthew Lewis, Forrest Jessop, Catherine Kendall, Dylan Gallegos, Arielle Hay, Cindi Schwartz, Rebecca Rosenke, Greg Saturday, Catherine M Bosio, Craig Martens, Sonja M Best

Journal: Cell Rep

PubMed ID: 34706234

Doi: 10.1016/j.celrep.2021.109888

Products & Services: Mammalian Expression

ACLY Nuclear Translocation in Human Macrophages Drives Proinflammatory Gene Expression by NF-κB Acetylation

Authors: Anna Santarsiero, Paolo Convertini, Simona Todisco, Ciro L Pierri, Anna De Grassi, Niamh C Williams, Dominga Iacobazzi, Giulio De Stefano, Luke A J O'Neill, Vittoria Infantino

Journal: Cells

PubMed ID: 34831186

Doi: 10.3390/cells10112962

Products & Services: Mutant Libraries

Characteristics of Two Crustins from in Hydrothermal Vents

Authors: Lu-Lu Guo, Shao-Lu Wang, Fang-Chao Zhu, Feng Xue, Li-Sheng He

Journal: Mar Drugs

PubMed ID: 34822471

Doi: 10.3390/md19110600

Products & Services: Proteins, Expression, Isolation and Analysis

A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG

Authors: María-Natalia Lisa, Adrià Sogues, Nathalie Barilone, Meike Baumgart, Magdalena Gil, Martín Graña, Rosario Durán, Ricardo M Biondi, Marco Bellinzoni, Michael Bott, Pedro M Alzari

Journal: MBio

PubMed ID: 34607462

Doi: 10.1128/mBio.01717-21

Products & Services: PCR and Cloning

p53 Transactivation Domain Mediates Binding and Phase Separation with Poly-PR/GR

Authors: Sinem Usluer, Emil Spreitzer, Benjamin Bourgeois, Tobias Madl

Journal: Int J Mol Sci

PubMed ID: 34768862

Doi: 10.3390/ijms222111431

Products & Services: Custom Vector Construction

Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase

Authors: Heather E Upton, Lucas Ferguson, Morayma M Temoche-Diaz, Xiao-Man Liu, Sydney C Pimentel, Nicholas T Ingolia, Randy Schekman, Kathleen Collins

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34649994

Doi: 10.1073/pnas.2107900118

Products & Services: ORF cDNA Clones/MolecularCloud

Impact of C-terminal truncations in the Arabidopsis Rab escort protein (REP) on REP-Rab interaction and plant fertility

Authors: Małgorzata Gutkowska, Magdalena Kaus-Drobek, Marta Hoffman-Sommer, Magdalena Małgorzata Pamuła, Anna Daria Leja, Małgorzata Perycz, Małgorzata Lichocka, Agnieszka Witek, Magdalena Wojtas, Michał Dadlez, Ewa Swiezewska, Liliana Surmacz

Journal: Plant J

PubMed ID: 34592024

Doi: 10.1111/tpj.15519

Products & Services: Monoclonal Antibody Services

Domain Analysis and Motif Matcher (DAMM): A Program to Predict Selectivity Determinants in PDZ Domains Using Human PDZ Data

Authors: Haley A Wofford, Josh Myers-Dean, Brandon A Vogel, Kevin Alexander Estrada Alamo, Frederick A Longshore-Neate, Filip Jagodzinski, Jeanine F Amacher

Journal: Molecules

PubMed ID: 34641578

Doi: 10.3390/molecules26196034

Products & Services: Gene Synthesis

Ambient Temperature Stable, Scalable COVID-19 Polymer Particle Vaccines Induce Protective Immunity

Authors: Shuxiong Chen, Benjamin Evert, Adetayo Adeniyi, Mercè Salla-Martret, Linda H-L Lua, Victoria Ozberk, Manisha Pandey, Michael F Good, Andreas Suhrbier, Peter Halfmann, Yoshihiro Kawaoka, Bernd H A Rehm

Journal: Adv Healthc Mater

PubMed ID: 34716678

Doi: 10.1002/adhm.202102089

Products & Services: Recombinant Proteins

The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome

Authors: Ivo A Hendriks, Sara C Buch-Larsen, Evgeniia Prokhorova, Jonas D Elsborg, Alexandra K L F S Rebak, Kang Zhu, Dragana Ahel, Claudia Lukas, Ivan Ahel, Michael L Nielsen

Journal: Nat Commun

PubMed ID: 34625544

Doi: 10.1038/s41467-021-26172-4

Products & Services: PCR and Cloning

Smart exosomes with lymph node homing and immune-amplifying capacities for enhanced immunotherapy of metastatic breast cancer

Authors: Panpan Ji, Zheng Yang, Hua Li, Mengying Wei, Guodong Yang, Helin Xing, Qiuyun Li

Journal: Mol Ther Nucleic Acids

PubMed ID: 34760340

Doi: 10.1016/j.omtn.2021.10.009

Products & Services: Gene Synthesis

Molecular switches regulating the potency and immune evasiveness of SARS-CoV-2 spike protein

Authors: Yushun Wan, Linfen Huang, Xiujuan Zhang, Jian Shang, Stanley Perlman, Lanying Du, Fang Li

Journal: Res Sq

PubMed ID: 34611654

Doi: 10.21203/rs.3.rs-736159/v2

Products & Services: Mammalian Expression

Apela inhibits systemic and renal inflammatory reactions in mice with type I cardiorenal syndrome

Authors: Liangli Jin, Quanyi Li, Jing Li, Yang Pan, Jue Zou, Xiaoyuan Wu, Zhi Wang

Journal: FASEB J

PubMed ID: 34516679

Doi: 10.1096/fj.202101030R

Products & Services: Proteins, Expression, Isolation and Analysis

JMJD8 is a Novel Molecular Nexus Between Adipocyte-Intrinsic Inflammation and Insulin Resistance

Authors: Dongjoo You, Byung Chul Jung, Sneha Damal Villivalam, Hee-Woong Lim, Sona Kang

Journal: Diabetes

PubMed ID: 34686520

Doi: 10.2337/db21-0596

Products & Services: Catalog Antibody

AgMYB12, a novel R2R3-MYB transcription factor, regulates apigenin biosynthesis by interacting with the AgFNS gene in celery

Authors: Hao Wang, Jie-Xia Liu, Kai Feng, Tong Li, Ao-Qi Duan, Yan-Hua Liu, Hui Liu, Ai-Sheng Xiong

Journal: Plant Cell Rep

PubMed ID: 34601645

Doi: 10.1007/s00299-021-02792-4

Products & Services: DNA Sequencing

Impact of circulating SARS-CoV-2 variants on mRNA vaccine-induced immunity

Authors: Carolina Lucas, Chantal B F Vogels, Inci Yildirim, Jessica E Rothman, Peiwen Lu, Valter Monteiro, Jeff R Gelhausen, Melissa Campbell, Julio Silva, Alexandra Tabachikova, Mario A Peña-Hernandez, M Catherine Muenker, Mallery I Breban, Joseph R Fauver, Subhasis Mohanty, Jiefang Huang, Albert C Shaw, Albert I Ko, Saad B Omer, Nathan D Grubaugh, Akiko Iwasaki

Journal: Nature

PubMed ID: 34634791

Doi: 10.1038/s41586-021-04085-y

Products & Services: Mammalian Expression

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