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页码: 165/1027 每页显示数量

MYB70 modulates seed germination and root system development in

Authors: Jinpeng Wan, Ruling Wang, Ping Zhang, Liangliang Sun, Qiong Ju, Haodong Huang, Shiyou Lü, Lam-Son Tran, Jin Xu

Journal: iScience

PubMed ID: 34746697

Doi: 10.1016/j.isci.2021.103228

Products & Services: Proteins, Expression, Isolation and Analysis

Structure-Function Analysis of Resistance to Bamlanivimab by SARS-CoV-2 Variants Kappa, Delta, and Lambda

Authors: Shufeng Liu, Tien Huynh, Charles B Stauft, Tony T Wang, Binquan Luan

Journal: J Chem Inf Model

PubMed ID: 34648284

Doi: 10.1021/acs.jcim.1c01058

Products & Services: Recombinant Proteins

Effect of Cotton Leafroll Dwarf Virus on Physiological Processes and Yield of Individual Cotton Plants

Authors: Ved Parkash, Divya Bhanu Sharma, John Snider, Sudeep Bag, Phillip Roberts, Afsha Tabassum, Dalton West, Sameer Khanal, Nelson Suassuna, Peng Chee

Journal: Front Plant Sci

PubMed ID: 34659302

Doi: 10.3389/fpls.2021.734386

Products & Services: PCR and Cloning

NLRC4 inflammasome-dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice

Authors: Peipei Zhang, Yifei Liu, Lichen Hu, Kai Huang, Mao Hong, Yuze Wang, Xinrui Fan, Richard J Ulevitch, Jiahuai Han

Journal: Sci Adv

PubMed ID: 34678072

Doi: 10.1126/sciadv.abi9471

Products & Services: PCR and Cloning

An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats

Authors: Martijn A Langereis, Irina C Albulescu, Judith Stammen-Vogelzangs, Morindy Lambregts, Ken Stachura, Suzan Miller, Angela M Bosco-Lauth, Airn E Hartwig, Stephanie M Porter, Michelle Allen, Mark Mogler, Frank J M van Kuppeveld, Berend-Jan Bosch, Paul Vermeij, Ad de Groof, Richard A Bowen, Randy Davis, Zach Xu, Ian Tarpey

Journal: npj Vaccines

PubMed ID: 34671047

Doi: 10.1038/s41541-021-00390-9

Products & Services: Recombinant Proteins

Abnormal Blood Coagulation and Kidney Damage in Aged Hamsters Infected with Severe Acute Respiratory Syndrome Coronavirus 2

Authors: Marumi Ohno, Michihito Sasaki, Yasuko Orba, Toshiki Sekiya, Md Abdul Masum, Osamu Ichii, Tatsuya Sawamura, Akemi Kakino, Yasuhiko Suzuki, Hiroshi Kida, Hirofumi Sawa, Masashi Shingai

Journal: Viruses

PubMed ID: 34834944

Doi: 10.3390/v13112137

Products & Services: Codon Optimization

The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity

Authors: Kevin J Forsberg, Danica T Schmidtke, Rachel Werther, Ruben V Uribe, Deanna Hausman, Morten O A Sommer, Barry L Stoddard, Brett K Kaiser, Harmit S Malik

Journal: PLoS Biol

PubMed ID: 34644300

Doi: 10.1371/journal.pbio.3001428

Products & Services: Mutant Libraries

Kinetochore-bound Mps1 regulates kinetochore-microtubule attachments via Ndc80 phosphorylation

Authors: Krishna K Sarangapani, Lori B Koch, Christian R Nelson, Charles L Asbury, Sue Biggins

Journal: J Cell Biol

PubMed ID: 34647959

Doi: 10.1083/jcb.202106130

Products & Services: GenParts™ DNA Fragments

Metabolic adaptation drives arsenic trioxide resistance in acute promyelocytic leukemia

Authors: Nithya Balasundaram, Saravanan Ganesan, Ezhilarasi Chendamarai, Hamenth Kumar Palani, Arvind Venkatraman, Ansu Abu Alex, Sachin David, Swathy Palanikumar, Nair Reeshma Radhakrishnan, Mohammed Yasar M, Sanjeev Krishna, Anu Korula, Uday Kulkarni, Nancy Beryl Janet, Poonkuzhali Balasubramanian, Vikram Mathews

Journal: Blood Adv

PubMed ID: 34625794

Doi: 10.1182/bloodadvances.2021005300

Products & Services: PCR and Cloning

Evolutionary transcriptomics implicates new genes and pathways in human pregnancy and adverse pregnancy outcomes

Authors: Katelyn Mika, Mirna Marinić, Manvendra Singh, Joanne Muter, Jan Joris Brosens, Vincent J Lynch

Journal: Elife

PubMed ID: 34623259

Doi: 10.7554/eLife.69584

Products & Services: Plasmid DNA Preparation

Pathogenic Mechanism of Der p 38 as a Novel Allergen Homologous to RipA and RipB Proteins in Atopic Dermatitis

Authors: Hyang Jeon, Geunyeong Kim, Ayesha Kashif, Min Hwa Hong, Ji-Sook Lee, Yujin Hong, Beom Seok Park, Eun Ju Yang, In Sik Kim

Journal: Front Immunol

PubMed ID: 34691014

Doi: 10.3389/fimmu.2021.646316

Products & Services: Endotoxin Detection & Removal System

The S Protein of Group B Is a Critical Virulence Determinant That Impacts the Cell Surface Virulome

Authors: Anaamika Campeau, Satoshi Uchiyama, Concepcion Sanchez, Consuelo Sauceda, Victor Nizet, David J Gonzalez

Journal: Front Microbiol

PubMed ID: 34721327

Doi: 10.3389/fmicb.2021.729308

Products & Services: Plasmid DNA Preparation

Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas

Authors: Keren Isaev, Lingyan Jiang, Shuai Wu, Christian A Lee, Valérie Watters, Victoire Fort, Ricky Tsai, Fiona J Coutinho, Samer M I Hussein, Jie Zhang, Jinsong Wu, Peter B Dirks, Daniel Schramek, Jüri Reimand

Journal: Cell Rep

PubMed ID: 34686327

Doi: 10.1016/j.celrep.2021.109873

Products & Services: PCR Cloning and Subcloning

Erratum: Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies

Authors:

Journal: Front Pharmacol

PubMed ID: 34744755

Doi: 10.3389/fphar.2021.788046

Products & Services: Peptide Synthesis

ACLY Nuclear Translocation in Human Macrophages Drives Proinflammatory Gene Expression by NF-κB Acetylation

Authors: Anna Santarsiero, Paolo Convertini, Simona Todisco, Ciro L Pierri, Anna De Grassi, Niamh C Williams, Dominga Iacobazzi, Giulio De Stefano, Luke A J O'Neill, Vittoria Infantino

Journal: Cells

PubMed ID: 34831186

Doi: 10.3390/cells10112962

Products & Services: Mutant Libraries

Characteristics of Two Crustins from in Hydrothermal Vents

Authors: Lu-Lu Guo, Shao-Lu Wang, Fang-Chao Zhu, Feng Xue, Li-Sheng He

Journal: Mar Drugs

PubMed ID: 34822471

Doi: 10.3390/md19110600

Products & Services: Proteins, Expression, Isolation and Analysis

A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG

Authors: María-Natalia Lisa, Adrià Sogues, Nathalie Barilone, Meike Baumgart, Magdalena Gil, Martín Graña, Rosario Durán, Ricardo M Biondi, Marco Bellinzoni, Michael Bott, Pedro M Alzari

Journal: MBio

PubMed ID: 34607462

Doi: 10.1128/mBio.01717-21

Products & Services: PCR and Cloning

p53 Transactivation Domain Mediates Binding and Phase Separation with Poly-PR/GR

Authors: Sinem Usluer, Emil Spreitzer, Benjamin Bourgeois, Tobias Madl

Journal: Int J Mol Sci

PubMed ID: 34768862

Doi: 10.3390/ijms222111431

Products & Services: Custom Vector Construction

Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase

Authors: Heather E Upton, Lucas Ferguson, Morayma M Temoche-Diaz, Xiao-Man Liu, Sydney C Pimentel, Nicholas T Ingolia, Randy Schekman, Kathleen Collins

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34649994

Doi: 10.1073/pnas.2107900118

Products & Services: ORF cDNA Clones/MolecularCloud

Impact of C-terminal truncations in the Arabidopsis Rab escort protein (REP) on REP-Rab interaction and plant fertility

Authors: Małgorzata Gutkowska, Magdalena Kaus-Drobek, Marta Hoffman-Sommer, Magdalena Małgorzata Pamuła, Anna Daria Leja, Małgorzata Perycz, Małgorzata Lichocka, Agnieszka Witek, Magdalena Wojtas, Michał Dadlez, Ewa Swiezewska, Liliana Surmacz

Journal: Plant J

PubMed ID: 34592024

Doi: 10.1111/tpj.15519

Products & Services: Monoclonal Antibody Services

Domain Analysis and Motif Matcher (DAMM): A Program to Predict Selectivity Determinants in PDZ Domains Using Human PDZ Data

Authors: Haley A Wofford, Josh Myers-Dean, Brandon A Vogel, Kevin Alexander Estrada Alamo, Frederick A Longshore-Neate, Filip Jagodzinski, Jeanine F Amacher

Journal: Molecules

PubMed ID: 34641578

Doi: 10.3390/molecules26196034

Products & Services: Gene Synthesis

Ambient Temperature Stable, Scalable COVID-19 Polymer Particle Vaccines Induce Protective Immunity

Authors: Shuxiong Chen, Benjamin Evert, Adetayo Adeniyi, Mercè Salla-Martret, Linda H-L Lua, Victoria Ozberk, Manisha Pandey, Michael F Good, Andreas Suhrbier, Peter Halfmann, Yoshihiro Kawaoka, Bernd H A Rehm

Journal: Adv Healthc Mater

PubMed ID: 34716678

Doi: 10.1002/adhm.202102089

Products & Services: Recombinant Proteins

The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome

Authors: Ivo A Hendriks, Sara C Buch-Larsen, Evgeniia Prokhorova, Jonas D Elsborg, Alexandra K L F S Rebak, Kang Zhu, Dragana Ahel, Claudia Lukas, Ivan Ahel, Michael L Nielsen

Journal: Nat Commun

PubMed ID: 34625544

Doi: 10.1038/s41467-021-26172-4

Products & Services: PCR and Cloning

Smart exosomes with lymph node homing and immune-amplifying capacities for enhanced immunotherapy of metastatic breast cancer

Authors: Panpan Ji, Zheng Yang, Hua Li, Mengying Wei, Guodong Yang, Helin Xing, Qiuyun Li

Journal: Mol Ther Nucleic Acids

PubMed ID: 34760340

Doi: 10.1016/j.omtn.2021.10.009

Products & Services: Gene Synthesis

Molecular switches regulating the potency and immune evasiveness of SARS-CoV-2 spike protein

Authors: Yushun Wan, Linfen Huang, Xiujuan Zhang, Jian Shang, Stanley Perlman, Lanying Du, Fang Li

Journal: Res Sq

PubMed ID: 34611654

Doi: 10.21203/rs.3.rs-736159/v2

Products & Services: Mammalian Expression

Apela inhibits systemic and renal inflammatory reactions in mice with type I cardiorenal syndrome

Authors: Liangli Jin, Quanyi Li, Jing Li, Yang Pan, Jue Zou, Xiaoyuan Wu, Zhi Wang

Journal: FASEB J

PubMed ID: 34516679

Doi: 10.1096/fj.202101030R

Products & Services: Proteins, Expression, Isolation and Analysis

JMJD8 is a Novel Molecular Nexus Between Adipocyte-Intrinsic Inflammation and Insulin Resistance

Authors: Dongjoo You, Byung Chul Jung, Sneha Damal Villivalam, Hee-Woong Lim, Sona Kang

Journal: Diabetes

PubMed ID: 34686520

Doi: 10.2337/db21-0596

Products & Services: Catalog Antibody

AgMYB12, a novel R2R3-MYB transcription factor, regulates apigenin biosynthesis by interacting with the AgFNS gene in celery

Authors: Hao Wang, Jie-Xia Liu, Kai Feng, Tong Li, Ao-Qi Duan, Yan-Hua Liu, Hui Liu, Ai-Sheng Xiong

Journal: Plant Cell Rep

PubMed ID: 34601645

Doi: 10.1007/s00299-021-02792-4

Products & Services: DNA Sequencing

Impact of circulating SARS-CoV-2 variants on mRNA vaccine-induced immunity

Authors: Carolina Lucas, Chantal B F Vogels, Inci Yildirim, Jessica E Rothman, Peiwen Lu, Valter Monteiro, Jeff R Gelhausen, Melissa Campbell, Julio Silva, Alexandra Tabachikova, Mario A Peña-Hernandez, M Catherine Muenker, Mallery I Breban, Joseph R Fauver, Subhasis Mohanty, Jiefang Huang, Albert C Shaw, Albert I Ko, Saad B Omer, Nathan D Grubaugh, Akiko Iwasaki

Journal: Nature

PubMed ID: 34634791

Doi: 10.1038/s41586-021-04085-y

Products & Services: Mammalian Expression

Genome Editing of Rice Loci Confers Partial Resistance to Rice Black-Streaked Dwarf Virus

Authors: Wei Wang, Shuhui Ma, Peng Hu, Yinghua Ji, Feng Sun

Journal: Viruses

PubMed ID: 34696530

Doi: 10.3390/v13102100

Products & Services: PCR Cloning and Subcloning

LncRNA DUXAP10 Upregulation and the Hedgehog Pathway Activation Are Critically Involved in Chronic Cadmium Exposure-Induced Cancer Stem Cell-Like Property

Authors: Hsuan-Pei Lin, Zhishan Wang, Chengfeng Yang

Journal: Toxicol Sci

PubMed ID: 34373904

Doi: 10.1093/toxsci/kfab099

Products & Services: PCR Cloning and Subcloning

Divergent degeneration of creA antitoxin genes from minimal CRISPRs and the convergent strategy of tRNA-sequestering CreT toxins

Authors: Feiyue Cheng, Rui Wang, Haiying Yu, Chao Liu, Jun Yang, Hua Xiang, Ming Li

Journal: Nucleic Acids Res

PubMed ID: 34551428

Doi: 10.1093/nar/gkab821

Products & Services: PCR and Cloning

The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress

Authors: Jun Tian, Yaojun Wang, Ming Ding, Yue Zhang, Jiaoni Chi, Tao Wang, Bin Jiao, Zhe Jian, Xiuli Yi, Ye Huang, Ling Liu, Kai Li, Jiaxi Chen, Gang Wang, Tianwen Gao, Chunying Li, Qiang Li

Journal: Oxid Med Cell Longev

PubMed ID: 34745423

Doi: 10.1155/2021/7617839

Products & Services: Nucleic Acid Purification & Analysis

Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes

Authors: Hüsün Sheyma Kizilkaya, Kimmie Vestergaard Sørensen, Camilla J Kibsgaard, Laerke Smidt Gasbjerg, Alexander S Hauser, Alexander Hovard Sparre-Ulrich, Niels Grarup, Mette M Rosenkilde

Journal: Front Cell Dev Biol

PubMed ID: 34760890

Doi: 10.3389/fcell.2021.749607

Products & Services: Mutant Libraries

Turnover of diacylglycerol kinase 4 by cytoplasmic acidification induces vacuole morphological change and nuclear DNA degradation in the early stage of pear self-incompatibility response

Authors: Xiao-Xiong Kong, Jia-Wei Mei, Jing Zhang, Xiao Liu, Ju-You Wu, Chun-Lei Wang

Journal: J Integr Plant Biol

PubMed ID: 34655280

Doi: 10.1111/jipb.13180

Products & Services: Monoclonal Antibody Services

Genome-wide analysis of the maize superoxide dismutase (SOD) gene family reveals important roles in drought and salt responses

Authors: Jing Liu, Lijuan Xu, Jian Shang, Xiaolin Hu, Haitao Yu, Hongying Wu, Wenben Lv, Yang Zhao

Journal: Genet Mol Biol

PubMed ID: 34606562

Doi: 10.1590/1678-4685-GMB-2021-0035

Products & Services: Molecular Biology Tools

Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension

Authors: Su-Jeong Kim, Anjali Devgan, Brendan Miller, Sam Mool Lee, Hiroshi Kumagai, Kenneth A Wilson, Gabriella Wassef, Richard Wong, Hemal H Mehta, Pinchas Cohen, Kelvin Yen

Journal: Biochim Biophys Acta Gen Subj

PubMed ID: 34624450

Doi: 10.1016/j.bbagen.2021.130017

Products & Services: Mammalian Expression

Signal inhibitory receptor on leukocytes-1 recognizes bacterial and endogenous amphipathic α-helical peptides

Authors: Matevž Rumpret, Helen J von Richthofen, Maarten van der Linden, Geertje H A Westerlaken, Cami Talavera Ormeño, Jos A G van Strijp, Meytal Landau, Huib Ovaa, Nina M van Sorge, Linde Meyaard

Journal: FASEB J

PubMed ID: 34533845

Doi: 10.1096/fj.202100812R

Products & Services: Mammalian Expression

fucosylation of CPN20 by SPINDLY Derepresses Abscisic Acid Signaling During Seed Germination and Seedling Development

Authors: Lin Liang, Qi Wang, Zihao Song, Yaxin Wu, Qing Liang, Qingsong Wang, Jinli Yang, Ying Bi, Wen Zhou, Liu-Min Fan

Journal: Front Plant Sci

PubMed ID: 34712252

Doi: 10.3389/fpls.2021.724144

Products & Services: Mammalian Expression

A glutamate concentration-biased allosteric modulator potentiates NMDA-induced ion influx in neurons

Authors: Blaise M Costa, Lina Cortés Kwapisz, Brittney Mehrkens, Douglas N Bledsoe, Bryanna N Vacca, Tullia V Johnston, Rehan Razzaq, Dhanasekaran Manickam, Bradley G Klein

Journal: Pharmacol Res Perspect

PubMed ID: 34476911

Doi: 10.1002/prp2.859

Products & Services: Mammalian Expression

Optimal flexibility of the linker region of Zika virus NS5 methyltransferase-polymerase is critical for virus replication

Authors: Charlotte Flory, Kitti Wing Ki Chan, Amanda Makha Bifani, Milly Ming Ju Choy, Julien Lescar, Eng Eong Ooi, Norbert Tautz, Subhash G Vasudevan

Journal: Antiviral Res

PubMed ID: 34699863

Doi: 10.1016/j.antiviral.2021.105194

Products & Services: GenParts™ DNA Fragments

The function of twister ribozyme variants in non-LTR retrotransposition in Schistosoma mansoni

Authors: Getong Liu, Hengyi Jiang, Wenxia Sun, Jun Zhang, Dongrong Chen, Alastair I H Murchie

Journal: Nucleic Acids Res

PubMed ID: 34551436

Doi: 10.1093/nar/gkab818

Products & Services: GenParts™ DNA Fragments

Enhanced prime editing systems by manipulating cellular determinants of editing outcomes

Authors: Peter J Chen, Jeffrey A Hussmann, Jun Yan, Friederike Knipping, Purnima Ravisankar, Pin-Fang Chen, Cidi Chen, James W Nelson, Gregory A Newby, Mustafa Sahin, Mark J Osborn, Jonathan S Weissman, Britt Adamson, David R Liu

Journal: Cell

PubMed ID: 34653350

Doi: 10.1016/j.cell.2021.09.018

Products & Services: GenParts™ DNA Fragments

Alkaline phosphatase attenuates LPS-induced liver injury by regulating the miR-146a-related inflammatory pathway

Authors: Haoming Wu, Yang Wang, Qianqian Yao, Linlin Fan, Lu Meng, Nan Zheng, Huiying Li, Jiaqi Wang

Journal: Int Immunopharmacol

PubMed ID: 34634739

Doi: 10.1016/j.intimp.2021.108149

Products & Services: Endotoxin Detection & Removal System

Incorporating health co-benefits into technology pathways to achieve China's 2060 carbon neutrality goal: a modelling study

Authors: Shihui Zhang, Kangxin An, Jin Li, Yuwei Weng, Shaohui Zhang, Shuxiao Wang, Wenjia Cai, Can Wang, Peng Gong

Journal: Lancet Planet Health

PubMed ID: 34758346

Doi: 10.1016/S2542-5196(21)00252-7

Products & Services: DNA Sequencing

GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis

Authors: Jonathan M Goodwin, Ward G Walkup, Kirsty Hooper, Taoyingnan Li, Chieko Kishi-Itakura, Aylwin Ng, Timothy Lehmberg, Archana Jha, Sravya Kommineni, Katherine Fletcher, Jorge Garcia-Fortanet, Yaya Fan, Qing Tang, Menghao Wei, Asmita Agrawal, Sagar R Budhe, Sreekanth R Rouduri, Dan Baird, Jeff Saunders, Janna Kiselar, Mark R Chance, Andrea Ballabio, Brent A Appleton, John H Brumell, Oliver Florey, Leon O Murphy

Journal: Sci Adv

PubMed ID: 34597140

Doi: 10.1126/sciadv.abj2485

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Identification of a MarR subfamily that regulates arsenic resistance genes

Authors: Yanshuang Yu, Jichen Chen, Yuanping Li, Jinxuan Liang, Zhenchen Xie, Renwei Feng, Hend A Alwathnani, Barry P Rosen, Anne Grove, Jian Chen, Christopher Rensing

Journal: Appl Environ Microbiol

PubMed ID: 34613763

Doi: 10.1128/AEM.01588-21

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Functional Characterization of a New Bifunctional Terpene Synthase LpNES1 from a Medicinal Plant Laggera pter odonta

Authors: Zhan-Ku Shi, Xiao-Wei Gong, Jiang-Yuan Zhao, Ming-Gang Li, Xiu-Lin Han, Meng-Liang Wen

Journal: J Oleo Sci

PubMed ID: 34645748

Doi: 10.5650/jos.ess21172

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NMR study of macro domains (MDs) from betacoronavirus: backbone resonance assignments of SARS-CoV and MERS-CoV MDs in the free and the ADPr-bound state

Authors: Aikaterini C Tsika, Nikolaos K Fourkiotis, Periklis Charalampous, Angelo Gallo, Georgios A Spyroulias

Journal: Biomol NMR Assign

PubMed ID: 34686999

Doi: 10.1007/s12104-021-10052-5

Products & Services: Custom Vector Construction

I-SceI and customized meganucleases-mediated genome editing in tomato and oilseed rape

Authors: Benoit Danilo, Émilie Montes, Héloïse Archambeau, Maryse Lodé, Mathieu Rousseau-Gueutin, Anne-Marie Chèvre, Marianne Mazier

Journal: Transgenic Res

PubMed ID: 34632562

Doi: 10.1007/s11248-021-00287-2

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