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Neuroligin 3 from common cutworm enhances the GABA-induced current of recombinant SlRDL1 channel

Authors: Ying Wang, Yi-Chi Zhang, Ke-Xin Zhang, Zhong-Qiang Jia, Tao Tang, Lin-Lin Zheng, Di Liu, Chun-Qing Zhao

Journal: Pest Manag Sci

PubMed ID: 34619015

Doi: 10.1002/ps.6669

Products & Services: PCR and Cloning

FCRL1 Regulates B Cell Receptor-Induced ERK Activation through GRB2

Authors: Jenna M DeLuca, Maegan K Murphy, Xin Wang, Timothy J Wilson

Journal: J Immunol

PubMed ID: 34697226

Doi: 10.4049/jimmunol.2100218

Products & Services: Mutagenesis Services

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

Authors: Vincent Dussupt, Rajeshwer S Sankhala, Letzibeth Mendez-Rivera, Samantha M Townsley, Fabian Schmidt, Lindsay Wieczorek, Kerri G Lal, Gina C Donofrio, Ursula Tran, Nathaniel D Jackson, Weam I Zaky, Michelle Zemil, Sarah R Tritsch, Wei-Hung Chen, Elizabeth J Martinez, Aslaa Ahmed, Misook Choe, William C Chang, Agnes Hajduczki, Ningbo Jian, Caroline E Peterson, Phyllis A Rees, Magdalena Rutkowska, Bonnie M Slike, Christopher N Selverian, Isabella Swafford, I-Ting Teng, Paul V Thomas, Tongqing Zhou, Clayton J Smith, Jeffrey R Currier, Peter D Kwong, Morgane Rolland, Edgar Davidson, Benjamin J Doranz, Christopher N Mores, Theodora Hatziioannou, William W Reiley, Paul D Bieniasz, Dominic Paquin-Proulx, Gregory D Gromowski, Victoria R Polonis, Nelson L Michael, Kayvon Modjarrad, M Gordon Joyce, Shelly J Krebs

Journal: Nat Immunol

PubMed ID: 34716452

Doi: 10.1038/s41590-021-01068-z

Products & Services: Monoclonal Antibody Services

Identification and characterization of arginine kinase, a novel allergen that causes cross-reactivity among shellfish

Authors: Fei Huan, Tian-Jiao Han, Meng Liu, Meng-Si Li, Yang Yang, Qing-Mei Liu, Dong Lai, Min-Jie Cao, Guang-Ming Liu

Journal: Food Funct

PubMed ID: 34664604

Doi: 10.1039/d1fo02042k

Products & Services: Molecular Biology Tools

The selective degradation of sirtuins via macroautophagy in the MPP model of Parkinson's disease is promoted by conserved oxidation sites

Authors: Marius W Baeken, Mario Schwarz, Andreas Kern, Bernd Moosmann, Parvana Hajieva, Christian Behl

Journal: Cell Death Discov

PubMed ID: 34642296

Doi: 10.1038/s41420-021-00683-x

Products & Services: Mammalian Expression

Poor protective potential of influenza nucleoprotein antibodies despite wide prevalence

Authors: Hillary A Vanderven, Robyn Esterbauer, Sinthujan Jegaskanda, Hyon-Xhi Tan, Adam K Wheatley, Stephen J Kent

Journal: Immunol Cell Biol

PubMed ID: 34687553

Doi: 10.1111/imcb.12508

Products & Services: Mammalian Expression

Ultrasensitive Detection of SARS-CoV-2 Spike Proteins Using the Thio-NAD Cycling Reaction: A Preliminary Study before Clinical Trials

Authors: Yuta Kyosei, Mayuri Namba, Daiki Makioka, Ayumi Kokubun, Satoshi Watabe, Teruki Yoshimura, Tadahiro Sasaki, Tatsuo Shioda, Etsuro Ito

Journal: Microorganisms

PubMed ID: 34835340

Doi: 10.3390/microorganisms9112214

Products & Services: Mammalian Expression

Nucleolin Aptamer N6L Reprograms the Translational Machinery and Acts Synergistically with mTORi to Inhibit Pancreatic Cancer Proliferation

Authors: Mounira Chalabi-Dchar, Elisabeth Cruz, Hichem C Mertani, Jean-Jacques Diaz, José Courty, Ilaria Cascone, Philippe Bouvet

Journal: Cancers (Basel)

PubMed ID: 34638443

Doi: 10.3390/cancers13194957

Products & Services: Mammalian Expression

Overexpression of a carrot BCH gene, DcBCH1, improves tolerance to drought in Arabidopsis thaliana

Authors: Tong Li, Jie-Xia Liu, Yuan-Jie Deng, Zhi-Sheng Xu, Ai-Sheng Xiong

Journal: BMC Plant Biol

PubMed ID: 34663216

Doi: 10.1186/s12870-021-03236-7

Products & Services: DNA Sequencing

Structural and allergenic properties of the Fatty Acid Binding Protein from shrimp Litopenaeus vannamei

Authors: Marlon Múnera, Dalgys Martínez, Judith Wortmann, Josefina Zakzuk, Walter Keller, Luis Caraballo, Leonardo Puerta

Journal: Allergy

PubMed ID: 34695231

Doi: 10.1111/all.15154

Products & Services: DNA Sequencing

Efficient Multi-Sites Genome Editing and Plant Regeneration Somatic Embryogenesis in

Authors: Ying Cui, Jian Zhao, Ying Gao, Ruirui Zhao, Jinfeng Zhang, Lisheng Kong

Journal: Front Plant Sci

PubMed ID: 34721480

Doi: 10.3389/fpls.2021.751891

Products & Services: DNA Sequencing

PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway

Authors: Gang Zhao, Xiaobao Shi, Zhanbo Sun, Pengfei Zhao, Zaiming Lu

Journal: Acta Biochim Biophys Sin (Shanghai)

PubMed ID: 34718369

Doi: 10.1093/abbs/gmab143

Products & Services: DNA Sequencing

Cardiovascular Progerin Suppression and lamin A Restoration Rescues Hutchinson-Gilford Progeria Syndrome

Authors: Amanda Sánchez-López, Carla Espinós-Estévez, Cristina González-Gómez, Pilar Gonzalo, María J Andrés-Manzano, Víctor Fanjul, Raquel Riquelme-Borja, Magda R Hamczyk, Álvaro Macías, Lara Del Campo, Emilio Camafeita, Jesús Vázquez, Anna Barkaway, Loïc Rolas, Sussan Nourshargh, Beatriz Dorado, Ignacio Benedicto, Vicente Andrés

Journal: Circulation

PubMed ID: 34694158

Doi: 10.1161/CIRCULATIONAHA.121.055313

Products & Services: Custom Vector Construction

The ubiquitous buried water in the beta-trefoil architecture contributes to the folding nucleus and ~20% of the folding enthalpy

Authors: Joseph B Parker, Connie A Tenorio, Michael Blaber

Journal: Protein Sci

PubMed ID: 34562298

Doi: 10.1002/pro.4192

Products & Services: Custom Vector Construction

Advancements in the Growth and Construction of Recombinant Lumpy Skin Disease Virus (LSDV) for Use as a Vaccine Vector

Authors: Michiel van Diepen, Rosamund Chapman, Nicola Douglass, Leah Whittle, Nicole Chineka, Shireen Galant, Christian Cotchobos, Akiko Suzuki, Anna-Lise Williamson

Journal: Vaccines (Basel)

PubMed ID: 34696239

Doi: 10.3390/vaccines9101131

Products & Services: Custom Vector Construction

A Chemical Strategy for Intracellular Arming of an Endogenous Broad-Spectrum Antiviral Nucleotide

Authors: Kellan T Passow, Haley S Caldwell, Kiet A Ngo, Jamie J Arnold, Nicole M Antczak, Anoop Narayanan, Joyce Jose, Shana J Sturla, Craig E Cameron, Alexander T Ciota, Daniel A Harki

Journal: J Med Chem

PubMed ID: 34661397

Doi: 10.1021/acs.jmedchem.1c01481

Products & Services: Custom DNA/RNA Oligos

Mutational analysis of TlyA from Brachyspira hampsonii reveals two key residues conserved in pathogenic bacteria responsible for oligomerization and hemolytic activity

Authors: Brandon A Keith, John C S Harding, Matthew E Loewen

Journal: Biochim Biophys Acta Gen Subj

PubMed ID: 34715264

Doi: 10.1016/j.bbagen.2021.130045

Products & Services: Codon Optimization

Repeating Aspartic Acid Residues Prefer Turn-like Conformations in the Unfolded State: Implications for Early Protein Folding

Authors: Bridget Milorey, Harald Schwalbe, Nichole O'Neill, Reinhard Schweitzer-Stenner

Journal: J Phys Chem B

PubMed ID: 34619031

Doi: 10.1021/acs.jpcb.1c06472

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Systemic and mucosal immune profiling in asymptomatic and symptomatic SARS-CoV-2-infected individuals reveal unlinked immune signatures

Authors: Supriya Ravichandran, Gabrielle Grubbs, Juanjie Tang, Youri Lee, Chang Huang, Hana Golding, Surender Khurana

Journal: Sci Adv

PubMed ID: 34644111

Doi: 10.1126/sciadv.abi6533

Products & Services: Mutagenesis Services

Synthetic virology: the experts speak

Authors:

Journal: Nat Biotechnol

PubMed ID: 34599304

Doi: 10.1038/s41587-021-01078-0

Products & Services: Gene Synthesis

Generation of recombinant vaccinia virus and analysis of virus-induced cell death

Authors: Zhijun Liu, Kidong Kang, Francis Ka-Ming Chan

Journal: STAR Protoc

PubMed ID: 34661172

Doi: 10.1016/j.xpro.2021.100871

Products & Services: Gene Synthesis

Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period

Authors: Wen-Heng Ji, Dan-Dan Li, Dan-Ping Wei, Ai-Qin Gu, Ying Yang, Jing-Pian Peng

Journal: Front Immunol

PubMed ID: 34712245

Doi: 10.3389/fimmu.2021.763067

Products & Services: Gene Synthesis

ZJUFB2 Prevents High Fat Diet-Induced Insulin Resistance in Association With Modulation of the Gut Microbiota

Authors: Hao Zhong, Jian Wang, Muhammad Adnan Hafeez, Rongfa Guan, Fengqin Feng

Journal: Front Nutr

PubMed ID: 34805244

Doi: 10.3389/fnut.2021.754222

Products & Services: Gene Synthesis

Natural diversity provides a broad spectrum of cyanobacteriochrome-based diguanylate cyclases

Authors: Matthew Blain-Hartung, Nathan C Rockwell, J Clark Lagarias

Journal: Plant Physiol

PubMed ID: 34608946

Doi: 10.1093/plphys/kiab240

Products & Services: Gene Synthesis

Phosphorylation Regulates CIRBP Arginine Methylation, Transportin-1 Binding and Liquid-Liquid Phase Separation

Authors: Aneta J Lenard, Saskia Hutten, Qishun Zhou, Sinem Usluer, Fangrong Zhang, Benjamin M R Bourgeois, Dorothee Dormann, Tobias Madl

Journal: Front Mol Biosci

PubMed ID: 34738012

Doi: 10.3389/fmolb.2021.689687

Products & Services: Gene Synthesis

Human serum albumin fusion protein as therapeutics for targeting amyloid beta in Alzheimer's diseases

Authors: Sookhee Bang, Jeong Kuen Song, Seung-Wook Shin, Kwan Hee Lee

Journal: Neurosci Lett

PubMed ID: 34673147

Doi: 10.1016/j.neulet.2021.136298

Products & Services: Gene Synthesis

Inhibition of viral suppressor of RNAi proteins by designer peptides protects from enteroviral infection in vivo

Authors: Yuan Fang , Zezhong Liu , Yang Qiu , Jing Kong, Yuhong Fu, Yujie Liu , Chong Wang , Jia Quan , Qian Wang , Wei Xu , Lei Yin , Jie Cui , Yi Xu , Stephen Curry , Shibo Jiang , Lu Lu , Xi Zhou

Journal: Immunity

PubMed ID: 34555337

Doi: 10.1016/j.immuni.2021.08.027

Products & Services: Peptide Synthesis

The Bacterial Amyloids Phenol Soluble Modulins from Catalyze Alpha-Synuclein Aggregation

Authors: Caroline Haikal, Lei Ortigosa-Pascual, Zahra Najarzadeh, Katja Bernfur, Alexander Svanbergsson, Daniel E Otzen, Sara Linse, Jia-Yi Li

Journal: Int J Mol Sci

PubMed ID: 34769023

Doi: 10.3390/ijms222111594

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Drug Repurposing for the SARS-CoV-2 Papain-Like Protease

Authors: Chia-Chuan Cho, Shuhua G Li, Tyler J Lalonde, Kai S Yang, Ge Yu, Yuchen Qiao, Shiqing Xu, Wenshe Ray Liu

Journal: ChemMedChem

PubMed ID: 34423563

Doi: 10.1002/cmdc.202100455

Products & Services: Proteins, Expression, Isolation and Analysis

Guillain-Barré Syndrome Associated with COVID-19 Vaccination

Authors: Shih-Chieh Shao, Chien-Ho Wang, Kai-Cheng Chang, Ming-Jui Hung, Hui-Yu Chen, Shu-Chen Liao

Journal: Emerg Infect Dis

PubMed ID: 34648420

Doi: 10.3201/eid2712.211634

Products & Services: Proteins, Expression, Isolation and Analysis

Comparative transcriptome analysis uncovers cell wall reorganization and repressed cell division during cotton fiber initiation

Authors: Wenyuan Liu, Yanjia Lv, Xiaoyue Li, Zongqin Feng, Lichen Wang

Journal: BMC Dev Biol

PubMed ID: 34715791

Doi: 10.1186/s12861-021-00247-3

Products & Services: Custom DNA/RNA Oligos

Reprogramming the metabolism of PCC 6803 by regulating the plastoquinone biosynthesis

Authors: Jianhua Fan, Dongqing Zhou, Cheng Chen, Ju Wu, Hui Wu

Journal: Synth Syst Biotechnol

PubMed ID: 34754966

Doi: 10.1016/j.synbio.2021.10.004

Products & Services: Codon Optimization

A BK channel-targeted peptide induces age-dependent improvement in behavioral and neural sound representation

Authors: Elliott J Brecht, Luisa L Scott, Bo Ding, Xiaoxia Zhu, Joseph P Walton

Journal: Neurobiol Aging

PubMed ID: 34861480

Doi: 10.1016/j.neurobiolaging.2021.10.014

Products & Services: Proteins, Expression, Isolation and Analysis

Overexpression of the Ginkgo biloba WD40 gene GbLWD1-like improves salt tolerance in transgenic Populus

Authors: Yue Xin, Yaqiong Wu, Xin Han, Li-An Xu

Journal: Plant Sci

PubMed ID: 34763876

Doi: 10.1016/j.plantsci.2021.111092

Products & Services: Bacterial Expression

WSB1 regulates c-Myc expression through -catenin signaling and forms a feedforward circuit

Authors: Xiaomeng Gao, Jieqiong You, Yanling Gong, Meng Yuan, Haiying Zhu, Liang Fang, Hong Zhu, Meidan Ying, Qiaojun He, Bo Yang, Ji Cao

Journal: Acta Pharm Sin B

PubMed ID: 35530152

Doi: 10.1016/j.apsb.2021.10.021

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Prior infection with SARS-CoV-2 boosts and broadens Ad26COV2S immunogenicity in a variant-dependent manner

Authors: Roanne Keeton, Simone I Richardson, Thandeka Moyo-Gwete, Tandile Hermanus, Marius B Tincho, Ntombi Benede, Nelia P Manamela, Richard Baguma, Zanele Makhado, Amkele Ngomti, Thopisang Motlou, Mathilda Mennen, Lionel Chinhoyi, Sango Skelem, Hazel Maboreke, Deelan Doolabh, Arash Iranzadeh, Ashley D Otter, Tim Brooks, Mahdad Noursadeghi, James C Moon, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Jonathan Blackburn, Nei-Yuan Hsiao, Carolyn Williamson, Catherine Riou, Ameena Goga, Nigel Garrett, Linda-Gail Bekker, Glenda Gray, Ntobeko A B Ntusi, Penny L Moore, Wendy A Burgers

Journal: Cell Host Microbe

PubMed ID: 34688376

Doi: 10.1016/j.chom.2021.10.003

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An inducible -Cre mouse model to monitor and manipulate -highly-expressing senescent cells

Authors: Binsheng Wang, Lichao Wang, Nathan S Gasek, Yueying Zhou, Taewan Kim, Chun Guo, Evan R Jellison, Laura Haynes, Sumit Yadav, Tamar Tchkonia, George A Kuchel, James L Kirkland, Ming Xu

Journal: Nat Aging

PubMed ID: 35024619

Doi: 10.1038/s43587-021-00107-6

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Cowpea Mosaic Virus Nanoparticle Vaccine Candidates Displaying Peptide Epitopes Can Neutralize the Severe Acute Respiratory Syndrome Coronavirus

Authors: Oscar A Ortega-Rivera, Sourabh Shukla, Matthew D Shin, Angela Chen, Veronique Beiss, Miguel A Moreno-Gonzalez, Yi Zheng, Alex E Clark, Aaron F Carlin, Jonathan K Pokorski, Nicole F Steinmetz

Journal: ACS Infect Dis

PubMed ID: 34672530

Doi: 10.1021/acsinfecdis.1c00410

Products & Services: Peptide Synthesis

Polymersomes as Stable Nanocarriers for a Highly Immunogenic and Durable SARS-CoV-2 Spike Protein Subunit Vaccine

Authors: Jian Hang Lam, Amit K Khan, Thomas A Cornell, Teck Wan Chia, Regine J Dress, Wen Wang William Yeow, Nur Khairiah Mohd-Ismail, Shrinivas Venkataraman, Kim Tien Ng, Yee-Joo Tan, Danielle E Anderson, Florent Ginhoux, Madhavan Nallani

Journal: ACS Nano

PubMed ID: 34618423

Doi: 10.1021/acsnano.1c01243

Products & Services: Recombinant Antibody Expression

Hantaviruses use the endogenous host factor P58IPK to combat the PKR antiviral response

Authors: Zekun Wang, Songyang Ren, Qiming Li, Austin D Royster, Lei Lin, Sichen Liu, Safder S Ganaie, Jianming Qiu, Sheema Mir, Mohammad A Mir

Journal: PLoS Pathog

PubMed ID: 34653226

Doi: 10.1371/journal.ppat.1010007

Products & Services: PCR and Cloning

Enzymatic extraction improves intracellular protein recovery from the industrial carrageenan seaweed revealed by quantitative, subcellular protein profiling: A high potential source of functional food ingredients

Authors: Simon Gregersen, Anne-Sofie Havgaard Kongsted, Rikke Brønnum Nielsen, Søren Storck Hansen, Frederik Andersen Lau, Jacob Bisgaard Rasmussen, Susan Løvstad Holdt, Charlotte Jacobsen

Journal: Food Chem X

PubMed ID: 34746746

Doi: 10.1016/j.fochx.2021.100137

Products & Services: Proteins, Expression, Isolation and Analysis

Ethylene Induced by Sound Stimulation Enhances Anthocyanin Accumulation in Grape Berry Skin through Direct Upregulation of UDP-Glucose: Flavonoid 3--Glucosyltransferase

Authors: Mone Yamazaki, Akari Ishida, Yutaka Suzuki, Yoshinao Aoki, Shunji Suzuki, Shinichi Enoki

Journal: Cells

PubMed ID: 34685779

Doi: 10.3390/cells10102799

Products & Services: PCR and Cloning

Reconstitution of Caveolin-1 into Artificial Lipid Membrane: Characterization by Transmission Electron Microscopy and Solid-State Nuclear Magnetic Resonance

Authors: Yanli Zhang, Xinyan Zhang, Wenru Kong, Shuqi Wang

Journal: Molecules

PubMed ID: 34684779

Doi: 10.3390/molecules26206201

Products & Services: Bacterial Expression

Using Continuous Directed Evolution to Improve Enzymes for Plant Applications

Authors: Jorge D García-García, Kristen Van Gelder, Jaya Joshi, Ulschan Bathe, Bryan J Leong, Steven D Bruner, Chang C Liu, Andrew D Hanson

Journal: Plant Physiol

PubMed ID: 34718794

Doi: 10.1093/plphys/kiab500

Products & Services: Recombinant Antibody Expression

A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy

Authors: Allison J Greaney, Tyler N Starr, Rachel T Eguia, Andrea N Loes, Khadija Khan, Farina Karim, Sandile Cele, John E Bowen, Jennifer K Logue, Davide Corti, David Veesler, Helen Y Chu, Alex Sigal, Jesse D Bloom

Journal: biorxiv

PubMed ID: 34671768

Doi: 10.1101/2021.10.12.464114

Products & Services: Proteins, Expression, Isolation and Analysis

Recombinant expression of insoluble enzymes in Escherichia coli: a systematic review of experimental design and its manufacturing implications

Authors: Suraj Mital, Graham Christie, Duygu Dikicioglu

Journal: Microb Cell Fact

PubMed ID: 34717620

Doi: 10.1186/s12934-021-01698-w

Products & Services: PCR and Cloning

Bivalent individualization during chromosome territory formation in Drosophila spermatocytes by controlled condensin II protein activity and additional force generators

Authors: Luisa Vernizzi, Christian F Lehner

Journal: PLoS Genet

PubMed ID: 34669718

Doi: 10.1371/journal.pgen.1009870

Products & Services: GenParts™ DNA Fragments

Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

Authors: Hillary H Le, Suleyman S Cinaroglu, Elise C Manalo, Aysegul Ors, Michelle M Gomes, Burcin Duan Sahbaz, Karla Bonic, Carlos A Origel Marmolejo, Arnaud Quentel, Justin S Plaut, Taryn E Kawashima, E Sila Ozdemir, Sanjay V Malhotra, Yavuz Ahiska, Ugur Sezerman, Gunseli Bayram Akcapinar, Joshua C Saldivar, Emel Timucin, Jared M Fischer

Journal: EBioMedicine

PubMed ID: 34689087

Doi: 10.1016/j.ebiom.2021.103646

Products & Services: Proteins, Expression, Isolation and Analysis

Stabilized coronavirus spike stem elicits a broadly protective antibody

Authors: Ching-Lin Hsieh, Anne P Werner, Sarah R Leist, Laura J Stevens, Ester Falconer, Jory A Goldsmith, Chia-Wei Chou, Olubukola M Abiona, Ande West, Kathryn Westendorf, Krithika Muthuraman, Ethan J Fritch, Kenneth H Dinnon, Alexandra Schäfer, Mark R Denison, James D Chappell, Ralph S Baric, Barney S Graham, Kizzmekia S Corbett, Jason S McLellan

Journal: Cell Rep

PubMed ID: 34710354

Doi: 10.1016/j.celrep.2021.109929

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Robust Neutralizing Antibody Responses 6 Months Post Vaccination with BNT162b2: A Prospective Study in 308 Healthy Individuals

Authors: Evangelos Terpos, Vangelis Karalis, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Sentiljana Gumeni, Panagiotis Malandrakis, Eleni-Dimitra Papanagnou, Efstathios Kastritis, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: Life (Basel)

PubMed ID: 34685448

Doi: 10.3390/life11101077

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