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Genome-wide identification and characterization of AINTEGUMENTA-LIKE (AIL) family genes in apple (Malus domestica Borkh)

Authors: Xiaolei Han, Kai Liu, Gaopeng Yuan, Shanshan He, Peihua Cong, Caixia Zhang

Journal: Genomics

PubMed ID: 35151838

Doi: 10.1016/j.ygeno.2022.110313

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NR3C2 suppresses the proliferation, migration, invasion and angiogenesis of colon cancer cells by inhibiting the AKT/ERK signaling pathway

Authors: Jia Li, Zhao Xu

Journal: Mol Med Rep

PubMed ID: 35191517

Doi: 10.3892/mmr.2022.12649

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Jasmonic acid biosynthetic genes TgLOX4 and TgLOX5 are involved in daughter bulb development in tulip (Tulipa gesneriana)

Authors: Qi Sun, Bei Zhang, Chaolong Yang, Weiliang Wang, Lin Xiang, Yanping Wang, Zhulong Chan

Journal: Hortic Res

PubMed ID: 35147193

Doi: 10.1093/hr/uhac006

Products & Services: Molecular Biology Tools

CRAF dimerization with ARAF regulates KRAS-driven tumor growth

Authors: Avinashnarayan Venkatanarayan, Jason Liang, Ivana Yen, Frances Shanahan, Benjamin Haley, Lilian Phu, Erik Verschueren, Trent B Hinkle, David Kan, Ehud Segal, Jason E Long, Tony Lima, Nicholas P D Liau, Jawahar Sudhamsu, Jason Li, Christiaan Klijn, Robert Piskol, Melissa R Junttila, Andrey S Shaw, Mark Merchant, Matthew T Chang, Donald S Kirkpatrick, Shiva Malek

Journal: Cell Rep

PubMed ID: 35139374

Doi: 10.1016/j.celrep.2022.110351

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Role of IL-17 in Morphogenesis and Dissemination of during Murine Infection

Authors: Nuria Trevijano-Contador, Elena Roselletti, Rocío García-Rodas, Anna Vecchiarelli, Óscar Zaragoza

Journal: Microorganisms

PubMed ID: 35208830

Doi: 10.3390/microorganisms10020373

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Placental methylome reveals a 22q1333 brain regulatory gene locus associated with autism

Authors: Yihui Zhu, J Antonio Gomez, Benjamin I Laufer, Charles E Mordaunt, Julia S Mouat, Daniela C Soto, Megan Y Dennis, Kelly S Benke, Kelly M Bakulski, John Dou, Ria Marathe, Julia M Jianu, Logan A Williams, Orangel J Gutierrez Fugón, Cheryl K Walker, Sally Ozonoff, Jason Daniels, Luke P Grosvenor, Heather E Volk, Jason I Feinberg, M Daniele Fallin, Irva Hertz-Picciotto, Rebecca J Schmidt, Dag H Yasui, Janine M LaSalle

Journal: Genome Biol

PubMed ID: 35168652

Doi: 10.1186/s13059-022-02613-1

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Antibody responses to 2 doses of mRNA Covid vaccine in pediatric renal patients

Authors: Alison Lap-Tak Ma, Daniel Leung, Eugene Yu-Hin Chan, Stella Chim, Samuel Cheng, Fanny Tsz-Wai Ho, Wai-Ming Lai, Pak-Chiu Tong, Matthew Hon-Lam Lee, Wilfred Hing-Sang Wong, Sau Man Chan, Jaime Rosa Duque, Joseph Sriyal Malik Peiris, Yu-Lung Lau

Journal: Kidney Int

PubMed ID: 35231464

Doi: 10.1016/j.kint.2022.01.035

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Engineered bacterial voltage-gated sodium channel platform for cardiac gene therapy

Authors: Hung X Nguyen, Tianyu Wu, Daniel Needs, Hengtao Zhang, Robin M Perelli, Sophia DeLuca, Rachel Yang, Michael Tian, Andrew P Landstrom, Craig Henriquez, Nenad Bursac

Journal: Nat Commun

PubMed ID: 35110560

Doi: 10.1038/s41467-022-28251-6

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Engineered EryF hydroxylase improving heterologous polyketide erythronolide B production in Escherichia coli

Authors: Zhifeng Liu, Jianlin Xu, Haili Liu, Yong Wang

Journal: Microb Biotechnol

PubMed ID: 35174640

Doi: 10.1111/1751-7915.14000

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Multiple Neuraminidase Containing Influenza Virus-like Particle Vaccines Protect Mice from Avian and Human Influenza Virus Infection

Authors: Hae-Ji Kang, Ki-Back Chu, Keon-Woong Yoon, Gi-Deok Eom, Jie Mao, Min-Ju Kim, Su-Hwa Lee, Eun-Kyung Moon, Fu-Shi Quan

Journal: Viruses

PubMed ID: 35216022

Doi: 10.3390/v14020429

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Recombinant Mosquito Densovirus with Toxins Significantly Improves Pathogenicity against

Authors: Khadija Batool, Intikhab Alam, Peiwen Liu, Zeng Shu, Siyu Zhao, Wenqiang Yang, Xiao Jie, Jinbao Gu, Xiao-Guang Chen

Journal: Toxins (Basel)

PubMed ID: 35202174

Doi: 10.3390/toxins14020147

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Cell surface nucleolin is a novel ADAMTS5 receptor mediating endothelial cell apoptosis

Authors: Dogan Can Kirman, Bhuvanasundar Renganathan, Wai Kit Chui, Ming Wei Chen, Neslihan Arife Kaya, Ruowen Ge

Journal: Cell Death Dis

PubMed ID: 35197459

Doi: 10.1038/s41419-022-04618-x

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Cytoplasmic switch of ARS2 isoforms promotes nonsense-mediated mRNA decay and arsenic sensitivity

Authors: Monica Mesa-Perez, Phineas T Hamilton, Alex Miranda, Nicholas Brodie, Connor O'Sullivan, Jennifer Christie, Bridget C Ryan, Robert L Chow, David Goodlett, Christopher J Nelson, Perry L Howard

Journal: Nucleic Acids Res

PubMed ID: 35104878

Doi: 10.1093/nar/gkac033

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MPLA-Adjuvanted Liposomes Encapsulating S-Trimer or RBD or S1, but Not S-ECD, Elicit Robust Neutralization Against SARS-CoV-2 and Variants of Concern

Authors: Jian Wang, Xu-Guang Yin, Yu Wen, Jie Lu, Ru-Yan Zhang, Shi-Hao Zhou, Chun-Miao Liao, Hua-Wei Wei, Jun Guo

Journal: J Med Chem

PubMed ID: 35108485

Doi: 10.1021/acs.jmedchem.1c02025

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An engineered bispecific human monoclonal antibody against SARS-CoV-2

Authors: Zhaohui Li, Shihua Li, Gen Zhang, Weiyu Peng, Zhen Chang, Xue Zhang, Zheng Fan, Yan Chai, Feiran Wang, Xin Zhao, Dedong Li, Rong Zhang, Zhanlong He, Weiwei Zou, Ke Xu, Wenwen Lei, Peipei Liu, Junfeng Hao, Jingjing Zhang, Litao Sun, Guizhen Wu, Shuguang Tan, George Fu Gao, Feng Gao, Yan Wu

Journal: Nat Immunol

PubMed ID: 35228696

Doi: 10.1038/s41590-022-01138-w

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Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer

Authors: Zhi Yang, Kim-Marie A Dam, Michael D Bridges, Magnus A G Hoffmann, Andrew T DeLaitsch, Harry B Gristick, Amelia Escolano, Rajeev Gautam, Malcolm A Martin, Michel C Nussenzweig, Wayne L Hubbell, Pamela J Bjorkman

Journal: Nat Commun

PubMed ID: 35136084

Doi: 10.1038/s41467-022-28424-3

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CRISPR-dCas9 based DNA detection scheme for diagnostics in resource-limited settings

Authors: Michel Bengtson, Mitasha Bharadwaj, Oskar Franch, Jaco van der Torre, Veronique Meerdink, Henk Schallig, Cees Dekker

Journal: Nanoscale

PubMed ID: 35044397

Doi: 10.1039/d1nr06557b

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Colicin E1 opens its hinge to plug TolC

Authors: S Jimmy Budiardjo, Jacqueline J Stevens, Anna L Calkins, Ayotunde P Ikujuni, Virangika K Wimalasena, Emre Firlar, David A Case, Julie S Biteen, Jason T Kaelber, Joanna S G Slusky

Journal: Elife

PubMed ID: 35199644

Doi: 10.7554/eLife.73297

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Heterologous Synthesis and Secretion of Ricinoleic Acid in Starmerella bombicola with Sophorolipid as an Intermediate

Authors: Mohor Chatterjee , Jay B Patel , Spencer T Stober, Xiaozhou Zhang

Journal: ACS Synth Biol

PubMed ID: 35157794

Doi: 10.1021/acssynbio.1c00457

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Discovery of potent and versatile CRISPR-Cas9 inhibitors engineered for chemically controllable genome editing

Authors: Guoxu Song , Fei Zhang , Chunhong Tian , Xing Gao, Xiaoxiao Zhu, Dongdong Fan, Yong Tian

Journal: Nucleic Acids Res

PubMed ID: 35188577

Doi: doi.org/10.1093/nar/gkac099

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African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-B Signaling Pathway

Authors: Qi Wang , Luyu Zhou , Jiang Wang , Dan Su , Dahua Li , Yongkun Du , Guoyu Yang , Gaiping Zhang , Beibei Chu

Journal: Viruses

PubMed ID: 35215987

Doi: 10.3390/v14020394

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Parallel profiling of antigenicity alteration and immune escape of SARS-CoV-2 Omicron and other variants

Authors: Cong Sun , Yin-Feng Kang , Yuan-Tao Liu , Xiang-Wei Kong , Hui-Qin Xu , Dan Xiong , Chu Xie , Yi-Hao Liu , Sui Peng , Guo-Kai Feng , Zheng Liu , Mu-Sheng Zeng

Journal: Signal Transduct Target Ther

PubMed ID: 35136040

Doi: 10.1038/s41392-022-00910-6

Products & Services: Gene Synthesis Protein and Antibody Isolation

Self-assembling ferritin nanoparticles coupled with linear sequences from canine distemper virus haemagglutinin protein elicit robust immune responses

Authors: Bo Wang, Shuang Li, Yongbo Qiao, Yu Fu, Jiaojiao Nie, Shun Jiang, Xin Yao, Yi Pan, Linye Zhao, Congmei Wu, Yuhua Shi, Yuhe Yin, Yaming Shan

Journal: J Nanobiotechnology

PubMed ID: 35012571

Doi: 10.1186/s12951-021-01229-0

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Nitroreduction of flutamide by NADPH: Cytochrome P450 reductase

Authors: Mohd Faheem Khan, Cormac D Murphy

Journal: Biochem Biophys Rep

PubMed ID: 35097225

Doi: 10.1016/j.bbrep.2022.101209

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Nitroreduction of flutamide by NADPH: Cytochrome P450 reductase

Authors: Mohd Faheem Khan, Cormac D Murphy

Journal: Biochem Biophys Rep

PubMed ID: 35097225

Doi: 10.1016/j.bbrep.2022.101209

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Crystal structure of the plant feruloyl-coenzyme A monolignol transferase provides insights into the formation of monolignol ferulate conjugates

Authors: Xi Liu, Shuliu Dai, Yu Zhou, Jinyue Liu, Dong Li, Jun Zhang, Yushan Zhu, Qiao Zhao, Yue Feng, Yi Zhang

Journal: Biochem Biophys Res Commun

PubMed ID: 35066379

Doi: 10.1016/j.bbrc.2022.01.037

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Crystal structure of the plant feruloyl-coenzyme A monolignol transferase provides insights into the formation of monolignol ferulate conjugates

Authors: Xi Liu, Shuliu Dai, Yu Zhou, Jinyue Liu, Dong Li, Jun Zhang, Yushan Zhu, Qiao Zhao, Yue Feng, Yi Zhang

Journal: Biochem Biophys Res Commun

PubMed ID: 35066379

Doi: 10.1016/j.bbrc.2022.01.037

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Preparation and characterization of 2-deacetyl-3-O-sulfo-heparosan and its antitumor effects via the fibroblast growth factor receptor pathway

Authors: Zhengqi Zha, Yaoyao Liu, Yinghua Miao, Shiying Liao, Su-Yan Wang, Huiling Tang, Hongping Yin

Journal: Int J Biol Macromol

PubMed ID: 34998873

Doi: 10.1016/j.ijbiomac.2021.12.098

Products & Services: Plasmid DNA Preparation

Degradation of dimethachlon by a newly isolated bacterium Paenarthrobacter sp strain JH-1 relieves its toxicity against Chlorella ellipsoidea

Authors: Mingliang Zhang, Wankui Jiang, Siyuan Gao, Qian Zhu, Zhijian Ke, Mingli Jiang, Jiguo Qiu, Qing Hong

Journal: Environ Res

PubMed ID: 35031339

Doi: 10.1016/j.envres.2022.112706

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Circ_HECTD1 regulates cerebral ischemia injury via mechanisms involving the regulation of let-7c-5p/ROCK1 axis

Authors: Qian Guo, Tingting Guo, Yuanyuan Sun, Tianrong Chen

Journal: Neuroreport

PubMed ID: 34874325

Doi: 10.1097/WNR.0000000000001743

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Bio-nanocapsules for oriented immobilization of DNA aptamers on aptasensors

Authors: Masumi Iijima, Yuki Yamada, Hideo Nakano, Tsutomu Nakayama, Shun'ichi Kuroda

Journal: Analyst

PubMed ID: 35023508

Doi: 10.1039/d1an02278d

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Longitudinal waning of mRNA vaccine-induced neutralizing antibodies against SARS-CoV-2 detected by an LFIA rapid test

Authors: Qiao Wang, Lili Feng, Haohai Zhang, Juehua Gao, Changchuin Mao, Esther Landesman-Bollag, Gustavo Mostoslavsky, Justin M Lunderberg, Weina Zheng, Shushun Hao, Wenda Gao

Journal: Antib Ther

PubMed ID: 35146332

Doi: 10.1093/abt/tbac004

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Involvement of β-cyanoalanine synthase (β-CAS) and sulfurtransferase (ST) in cyanide (CN) assimilation in rice seedlings

Authors: Yu-Xi Feng, Cheng-Zhi Li, Yu-Juan Lin, Xiao-Zhang Yu

Journal: Chemosphere

PubMed ID: 35101430

Doi: 10.1016/j.chemosphere.2022.133789

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Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence

Authors: Stefano Perni, Kurt Beam

Journal: J Gen Physiol

PubMed ID: 35089322

Doi: 10.1085/jgp.202113024

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Roles of Close Homologues SigB and SigD in Heat and High Light Acclimation of the Cyanobacterium sp PCC 6803

Authors: Otso Turunen, Satu Koskinen, Juha Kurkela, Outi Karhuvaara, Kaisa Hakkila, Taina Tyystjärvi

Journal: Life (Basel)

PubMed ID: 35207450

Doi: 10.3390/life12020162

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Roles of Close Homologues SigB and SigD in Heat and High Light Acclimation of the Cyanobacterium sp PCC 6803

Authors: Otso Turunen, Satu Koskinen, Juha Kurkela, Outi Karhuvaara, Kaisa Hakkila, Taina Tyystjärvi

Journal: Life (Basel)

PubMed ID: 35207450

Doi: 10.3390/life12020162

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Crystal Structure Analysis and IgE Epitope Mapping of Allergic Predominant Region in Filamin C, Scy p 9

Authors: Xin-Rong He, Yang Yang, Shuai Kang, Ye-Xin Chen, Pei-Yi Zheng, Gui-Xia Chen, Xiao-Mei Chen, Min-Jie Cao, Tengchuan Jin, Guang-Ming Liu

Journal: J Agric Food Chem

PubMed ID: 35040643

Doi: 10.1021/acs.jafc.1c07922

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Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells

Authors: Yong Bian, Gang Yin, Gang Wang, Tiantian Liu, Li Liang, Xinyue Yang, Wen Zhang, Decai Tang

Journal: Cell Biol Toxicol

PubMed ID: 35083610

Doi: 10.1007/s10565-021-09681-2

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Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells

Authors: Yong Bian, Gang Yin, Gang Wang, Tiantian Liu, Li Liang, Xinyue Yang, Wen Zhang, Decai Tang

Journal: Cell Biol Toxicol

PubMed ID: 35083610

Doi: 10.1007/s10565-021-09681-2

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CryoEM analysis of small plant biocatalysts at sub-2 Å resolution

Authors: Nicole Dimos, Carl P O Helmer, Andrea M Chánique, Markus C Wahl, Robert Kourist, Tarek Hilal, Bernhard Loll

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 34981767

Doi: 10.1107/S205979832101216X

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CryoEM analysis of small plant biocatalysts at sub-2 Å resolution

Authors: Nicole Dimos, Carl P O Helmer, Andrea M Chánique, Markus C Wahl, Robert Kourist, Tarek Hilal, Bernhard Loll

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 34981767

Doi: 10.1107/S205979832101216X

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DNA methylation analysis of ELOVL2 gene using droplet digital PCR for age estimation purposes

Authors: Licínio Manco, Helena Correia Dias

Journal: FORENSIC SCI INT

PubMed ID: 35131731

Doi: 10.1016/j.forsciint.2022.111206

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DNA methylation analysis of ELOVL2 gene using droplet digital PCR for age estimation purposes

Authors: Licínio Manco, Helena Correia Dias

Journal: FORENSIC SCI INT

PubMed ID: 35131731

Doi: 10.1016/j.forsciint.2022.111206

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Uncoupling the Excitatory Amino Acid Transporter 2 From Its C-Terminal Interactome Restores Synaptic Glutamate Clearance at Corticostriatal Synapses and Alleviates Mutant Huntingtin-Induced Hypokinesia

Authors: Stefan Hirschberg, Anton Dvorzhak, Seyed M A Rasooli-Nejad, Svilen Angelov, Marieluise Kirchner, Philipp Mertins, Gilla Lättig-Tünnemann, Christoph Harms, Dietmar Schmitz, Rosemarie Grantyn

Journal: Front Cell Neurosci

PubMed ID: 35173582

Doi: 10.3389/fncel.2021.792652

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Journal: Front Cell Neurosci

PubMed ID: 35173582

Doi: 10.3389/fncel.2021.792652

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Eradication of Myrosinase-Tethered Cancer Cells by Allyl Isothiocyanate Derived from Enzymatic Hydrolysis of Sinigrin

Authors: Ammar Tarar, Esmael M Alyami, Ching-An Peng

Journal: Pharmaceutics

PubMed ID: 35057038

Doi: 10.3390/pharmaceutics14010144

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Eradication of Myrosinase-Tethered Cancer Cells by Allyl Isothiocyanate Derived from Enzymatic Hydrolysis of Sinigrin

Authors: Ammar Tarar, Esmael M Alyami, Ching-An Peng

Journal: Pharmaceutics

PubMed ID: 35057038

Doi: 10.3390/pharmaceutics14010144

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Exogenous Chemical Exposure Increased Transcription Levels of the Host Virus Receptor Involving Coronavirus Infection

Authors: Xiaoting Jin, Jingxu Zhang, Yanting Li, Ze Zhang, Tenglong Cui, Yuanyuan Wang, Linlin Yao, Xiaoxi Yang, Guangbo Qu, Yuxin Zheng, Guibin Jiang

Journal: Environ Sci Technol

PubMed ID: 35049283

Doi: 10.1021/acs.est.1c07172

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Genome-wide identification and expression profile of YABBY genes in

Authors: Chengru Li, Na Dong, Liming Shen, Meng Lu, Junwen Zhai, Yamei Zhao, Lei Chen, Zhiting Wan, Zhongjian Liu, Hui Ren, Shasha Wu

Journal: PeerJ

PubMed ID: 35036123

Doi: 10.7717/peerj.12558

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Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain

Authors: Nathaniel L Miller, Thomas Clark, Rahul Raman, Ram Sasisekharan

Journal: Cell Rep Med

PubMed ID: 35233548

Doi: 10.1016/j.xcrm.2022.100527

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