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页码: 156/1028 每页显示数量
A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants
Authors: Novalia Pishesha, Thibault J Harmand, Paul W Rothlauf, Patrique Praest, Ryan K Alexander, Renate van den Doel, Mariel J Liebeskind, Maria A Vakaki, Nicholas McCaul, Charlotte Wijne, Elisha Verhaar, William Pinney, Hailey Heston, Louis-Marie Bloyet, Marjorie Cornejo Pontelli, Ma Xenia G Ilagan, Robert Jan Lebbink, William J Buchser, Emmanuel J H J Wiertz, Sean P J Whelan, Hidde L Ploegh
Journal: Proc Natl Acad Sci U S A
PubMed ID: 34654739
Doi: 10.1073/pnas.2116147118
Products & Services: Catalog Peptides   
First cases of SARS-CoV-2 infection in dogs and cats in Thailand
Authors: Waleemas Jairak, Kamonpan Charoenkul, Ekkapat Chamsai, Kitikhun Udom, Supassama Chaiyawong, Napawan Bunpapong, Supanat Boonyapisitsopa, Rachod Tantilertcharoen, Navapon Techakriengkrai, Sirilak Surachetpong, Ratanaporn Tangwangvivat, Kamol Suwannakarn, Alongkorn Amonsin
Journal: Transbound Emerg Dis
PubMed ID: 34739748
Doi: 10.1111/tbed.14383
Immune signatures underlying post-acute COVID-19 lung sequelae
Authors: I S Cheon, C Li, Y M Son, N P Goplen, Y Wu, T Cassmann, Z Wang, X Wei, J Tang, Y Li, H Marlow, S Hughes, L Hammel, T M Cox, E Goddery, K Ayasoufi, D Weiskopf, J Boonyaratanakornkit, H Dong, H Li, R Chakraborty, A J Johnson, E Edell, J J Taylor, M H Kaplan, A Sette, B J Bartholmai, R Kern, R Vassallo, J Sun
Journal: Sci Immunol
PubMed ID: 34591653
Doi: 10.1126/sciimmunol.abk1741
Characterization of a novel transcript variant: implications for D6D activity regulation in cells
Authors: Kristin A Marks, Maria F Fernandes, Kalsha H Diaguarachchige De Silva, Michelle V Tomczewski, Ken D Stark, Robin E Duncan
Journal: Biochem Cell Biol
PubMed ID: 34738827
Doi: 10.1139/bcb-2020-0538
Products & Services: Plasmid DNA Preparation   
Hybridization-proximity labeling reveals spatially ordered interactions of nuclear RNA compartments
Authors: Karen Yap, Tek Hong Chung, Eugene V Makeyev
Journal: Mol Cell
PubMed ID: 34741808
Doi: 10.1016/j.molcel.2021.10.009
Products & Services: Custom DNA/RNA Oligos   
Increased carvone production in Escherichia coli by balancing limonene conversion enzyme expression via targeted quantification concatamer proteome analysis
Authors: Erika Yoshida, Motoki Kojima, Munenori Suzuki, Fumio Matsuda, Kazutaka Shimbo, Akiko Onuki, Yousuke Nishio, Yoshihiro Usuda, Akihiko Kondo, Jun Ishii
Journal: Sci Rep
PubMed ID: 34764337
Doi: 10.1038/s41598-021-01469-y
Products & Services: Bacterial Expression   
Zipper head mechanism of telomere synthesis by human telomerase
Authors: Futang Wan, Yongbo Ding, Yuebin Zhang, Zhenfang Wu, Shaobai Li, Lin Yang, Xiangyu Yan, Pengfei Lan, Guohui Li, Jian Wu, Ming Lei
Journal: Cell Res
PubMed ID: 34782750
Doi: 10.1038/s41422-021-00586-7
Quench-Release-Based Fluorescent Immunosensor for the Rapid Detection of Tumor Necrosis Factor α
Authors: Haimei Li, Xinyu Li, Limei Chen, Baowei Li, Hang Dong, Hongying Liu, Xueying Yang, Hiroshi Ueda, Jinhua Dong
Journal: ACS Omega
PubMed ID: 34841143
Doi: 10.1021/acsomega.1c03941
Humoral immune response following prime and boost BNT162b2 vaccination in people living with HIV on antiretroviral therapy
Authors: Nils Jedicke, Metodi V Stankov, Anne Cossmann, Alexandra Dopfer-Jablonka, Christine Knuth, Gerrit Ahrenstorf, Gema Morillas Ramos, Georg M N Behrens
Journal: HIV Med
PubMed ID: 34725907
Doi: 10.1111/hiv.13202
Inhibition of miR-15a-5p Promotes the Chemoresistance to Pirarubicin in Hepatocellular Carcinoma via Targeting eIF4E
Authors: Ying Zhang, Qingsong Tie, Zhiwei Bao, Zhi Shao, Lan Zhang
Journal: Comput Math Methods Med
PubMed ID: 34812269
Doi: 10.1155/2021/6468405
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Co-translational biogenesis of lipid droplet integral membrane proteins
Authors: Pawel Leznicki, Hayden O Schneider, Jada V Harvey, Wei Q Shi, Stephen High
Journal: J Cell Sci
PubMed ID: 34558621
Doi: 10.1242/jcs.259220
The ZO-1 protein Polychaetoid as an upstream regulator of the Hippo pathway in Drosophila
Authors: Qingliang Sang, Gang Wang, David B Morton, Hui Wu, Baotong Xie
Journal: PLoS Genet
PubMed ID: 34748546
Doi: 10.1371/journal.pgen.1009894
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Phytochrome interacting factor 3 regulates pollen mitotic division through auxin signalling and sugar metabolism pathways in tomato
Authors: Dandan Yang, Yue Liu, Muhammad Ali, Lei Ye, Changtian Pan, Mengzhuo Li, Xiaolin Zhao, Fangjie Yu, Xinai Zhao, Gang Lu
Journal: New Phytol
PubMed ID: 34812499
Doi: 10.1111/nph.17878
Immunoglobulin a suppresses B cell receptor-mediated activation of mouse B cells with differential inhibition of signaling molecules
Authors: Kouya Yamaki, Masato Terashi, Saori Yamamoto, Rei Fujiwara, Jun-Ichi Inoue, Kishi Shimizu, Sakura Yanagita, Yuma Doi, Kei-Ichiro Kimura, Kayo Kotani, Mai Sugihara, Yutaka Koyama
Journal: Immunopharmacol Immunotoxicol
PubMed ID: 34844505
Doi: 10.1080/08923973.2021.2006216
Products & Services: Endotoxin Detection & Removal System   
Hsa_circ_0003204 Knockdown Weakens Ox-LDL-Induced Cell Injury by Regulating miR-188-3p/TRPC6 Axis in Human Carotid Artery Endothelial Cells and THP-1 Cells
Authors: Wenjia Peng, Shuai Li, Shiyue Chen, Jiacheng Yang, Ze Sun
Journal: Front Cardiovasc Med
PubMed ID: 34912856
Doi: 10.3389/fcvm.2021.731890
Products & Services: Custom DNA/RNA Oligos   
Highly portable quantitative screening test for prostate-specific antigen at point of care
Authors: Balaji Srinivasan, David M Nanus, David Erickson, Saurabh Mehta
Journal: Curr Res Biotechnol
PubMed ID: 35083431
Doi: 10.1016/j.crbiot.2021.11.003
Products & Services: Bacterial Expression   
Noncanonical ER-Golgi trafficking and autophagy of endogenous procollagen in osteoblasts
Authors: Laura Gorrell, Shakib Omari, Elena Makareeva, Sergey Leikin
Journal: Cell Mol Life Sci
PubMed ID: 34779895
Doi: 10.1007/s00018-021-04017-z
Products & Services: Synthetic sgRNA and crRNA Service   Gene Synthesis   
Association Between Brain Structural Network Efficiency at Term-Equivalent Age and Early Development of Cerebral Palsy in Very Preterm Infants
Authors: Julia E Kline, Weihong Yuan, Karen Harpster, Mekibib Altaye, Nehal A Parikh
Journal: Neuroimage
PubMed ID: 34758381
Doi: 10.1016/j.neuroimage.2021.118688
Products & Services: Recombinant Proteins   
Preparation of Specific Nanobodies and Their Application in the Rapid Detection of Nodularin-R in Water Samples
Authors: Jinyi Yang, Rui Si, Guangpei Wu, Yu Wang, Ruyu Fang, Fei Liu, Feng Wang, Hongtao Lei, Yudong Shen, Qi Zhang, Hong Wang
Journal: Foods
PubMed ID: 34829042
Doi: 10.3390/foods10112758
Products & Services: Recombinant Antibody Expression   
Comparison of SARS-CoV-2 Antibody Responses and Seroconversion in COVID-19 Patients Using Twelve Commercial Immunoassays
Authors: Sojeong Yun, Ji Hyeong Ryu, Joo Hee Jang, Hyunjoo Bae, Seung-Hyo Yoo, Ae-Ran Choi, Sung Jin Jo, Jihyang Lim, Jehoon Lee, Hyejin Ryu, Sung-Yeon Cho, Dong-Gun Lee, Jongmin Lee, Seok Chan Kim, Yeon-Joon Park, Hyeyoung Lee, Eun-Jee Oh
Journal: Ann Lab Med
PubMed ID: 34108285
Doi: 10.3343/alm.2021.41.6.577
Quantitative assessment of AD markers using naked eyes: point-of-care testing with paper-based lateral flow immunoassay
Authors: Liding Zhang, Xuewei Du, Ying Su, Shiqi Niu, Yanqing Li, Xiaohan Liang, Haiming Luo
Journal: J Nanobiotechnology
PubMed ID: 34789291
Doi: 10.1186/s12951-021-01111-z
Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling
Authors: Dahong Chen, Catherine E McManus, Behram Radmanesh, Leah H Matzat, Elissa P Lei
Journal: Nat Commun
PubMed ID: 34737269
Doi: 10.1038/s41467-021-26628-7
Products & Services: Plasmid DNA Preparation   
Transformation of Reactive Blue 19 by a recombinant peroxidase DyP
Authors: Qian Pi, Zhubing Zhu, Lei Tang
Journal: Bioprocess Biosyst Eng
PubMed ID: 34739595
Doi: 10.1007/s00449-021-02660-1
Products & Services: Plasmid DNA Preparation   
Honokiol improves cognitive impairment in APP/PS1 mice through activating mitophagy and mitochondrial unfolded protein response
Authors: Mingyue Hou, Wenfang Bao, Yuanyuan Gao, Jiayue Chen, Guijun Song
Journal: Chem Biol Interact
PubMed ID: 34752757
Doi: 10.1016/j.cbi.2021.109741
Products & Services: Plasmid DNA Preparation   
Modulating Oncolytic Adenovirus Immunotherapy by Driving Two Axes of the Immune System by Expressing 4-1BBL and CD40L
Authors: Shao-Chia Lu, Michael Hansen, Jack Hemsath, Brian Parrett, Brady Zell, Michael A Barry
Journal: Hum Gene Ther
PubMed ID: 34731019
Doi: 10.1089/hum.2021.197
Products & Services: Peptide Synthesis   
Effective discrimination of gas-phase peptide conformers using TIMS-ECD-ToF MS/MS
Authors: K Jeanne Dit Fouque, M Wellmann, D Leyva Bombuse, M Santos-Fernandez, Y L Cintron-Diaz, M E Gomez-Hernandez, D Kaplan, V G Voinov, F Fernandez-Lima
Journal: Anal Methods
PubMed ID: 34698320
Doi: 10.1039/d1ay01461g
Products & Services: ORF cDNA Clones/MolecularCloud   
Author Correction: Regulation of local GTP availability controls RAC1 activity and cell invasion
Authors: Anna Bianchi-Smiraglia, David W Wolff, Daniel J Marston, Zhiyong Deng, Zhannan Han, Sudha Moparthy, Rebecca M Wombacher, Ashley L Mussell, Shichen Shen, Jialin Chen, Dong-Hyun Yun, Anderson O'Brien Cox, Cristina M Furdui, Edward Hurley, Maria Laura Feltri, Jun Qu, Thomas Hollis, Jules Berlin Nde Kengne, Bernard Fongang, Rui J Sousa, Mikhail E Kandel, Eugene S Kandel, Klaus M Hahn, Mikhail A Nikiforov
Journal: Nat Commun
PubMed ID: 34741006
Doi: 10.1038/s41467-021-26665-2
Products & Services: Mutant Libraries   
Molecular Detection and Characterization of in Farmed Pigs in Three Provinces of Southern China
Authors: Yang Zou, Xiao-Dan Yuan, Sheng-Ying Zhang, Hong-Yan Zhang, Xiao-Qing Chen
Journal: Pathogens
PubMed ID: 34832636
Doi: 10.3390/pathogens10111481
Products & Services: DNA Sequencing   
African Swine Fever Virus pI215L Negatively Regulates cGAS-STING Signaling Pathway through Recruiting RNF138 to Inhibit K63-Linked Ubiquitination of TBK1
Authors: Li Huang, Wenjie Xu, Hongyang Liu, Mengdi Xue, Xiaohong Liu, Kunli Zhang, Liang Hu, Jiangnan Li, Xuemin Liu, Zhida Xiang, Jun Zheng, Changyao Li, Weiye Chen, Zhigao Bu, Tao Xiong, Changjiang Weng
Journal: J Immunol
PubMed ID: 34759016
Doi: 10.4049/jimmunol.2100320
Products & Services: Custom Vector Construction   
Rescuing activity of oxygen-damaged pyruvate formate-lyase by a spare part protein
Authors: Mary C Andorfer, Lindsey R F Backman, Phoebe L Li, Emily C Ulrich, Catherine L Drennan
Journal: J Biol Chem
PubMed ID: 34801558
Doi: 10.1016/j.jbc.2021.101423
Products & Services: Codon Optimization   
Engineering Cupriavidus necator DSM 545 for the one-step conversion of starchy waste into polyhydroxyalkanoates
Authors: Silvia Brojanigo, Nicoletta Gronchi, Tiziano Cazzorla, Tuck Seng Wong, Marina Basaglia, Lorenzo Favaro, Sergio Casella
Journal: Bioresour Technol
PubMed ID: 34808314
Doi: 10.1016/j.biortech.2021.126383
Products & Services: Codon Optimization   
Identification and Characterization of Thermostable Y-Family DNA Polymerases η, ι, κ and Rev1 From a Lower Eukaryote, Thermomyces lanuginosus
Authors: Alexandra Vaisman, John P McDonald, Mallory R Smith, Sender L Aspelund, Thomas C Evans, Roger Woodgate
Journal: Front Mol Biosci
PubMed ID: 34805283
Doi: 10.3389/fmolb.2021.778400
Products & Services: Codon Optimization   
Evaluation of Cellular Immunity with ASFV Infection by Swine Leukocyte Antigen (SLA)-Peptide Tetramers
Authors: Wenqiang Sun, He Zhang, Wenhui Fan, Lihong He, Teng Chen, Xintao Zhou, Yu Qi, Lei Sun, Rongliang Hu, Tingrong Luo, Wenjun Liu, Jing Li
Journal: Viruses
PubMed ID: 34835070
Doi: 10.3390/v13112264
Products & Services: Codon Optimization   
Disulfide Bonds Play a Critical Role in the Structure and Function of the Receptor-binding Domain of the SARS-CoV-2 Spike Antigen
Authors: Andrey M Grishin, Nataliya V Dolgova, Shelby Landreth, Olivier Fisette, Ingrid J Pickering, Graham N George, Darryl Falzarano, Miroslaw Cygler
Journal: J Mol Biol
PubMed ID: 34780781
Doi: 10.1016/j.jmb.2021.167357
Products & Services: Codon Optimization   
Structure of procarboxypeptidase B1 and its binding with Dengue virus for controlling infection
Authors: Edem Gavor, Yeu Khai Choong, Nikhil Kumar Tulsian, Digant Nayak, Fakhriedzwan Idris, Hariharan Sivaraman, Donald Heng Rong Ting, Alonso Sylvie, Yu Keung Mok, R Manjunatha Kini, J Sivaraman
Journal: Life Sci Alliance
PubMed ID: 34750241
Doi: 10.26508/lsa.202101211
Products & Services: Codon Optimization   
Tyrosinase-based production of L-DOPA by Corynebacterium glutamicum
Authors: Eldin Kurpejović, Volker F Wendisch, Berna Sariyar Akbulut
Journal: Appl Microbiol Biotechnol
PubMed ID: 34762142
Doi: 10.1007/s00253-021-11681-5
Products & Services: Codon Optimization   
Overexpression of the rice BAHD acyltransferase AT10 increases xylan-bound p-coumarate and reduces lignin in Sorghum bicolor
Authors: Yang Tian, Chien-Yuan Lin, Joon-Hyun Park, Chuan-Yin Wu, Ramu Kakumanu, Venkataramana R Pidatala, Khanh M Vuu, Alberto Rodriguez, Patrick M Shih, Edward E K Baidoo, Stephen Temple, Blake A Simmons, John M Gladden, Henrik V Scheller, Aymerick Eudes
Journal: Biotechnol Biofuels
PubMed ID: 34801067
Doi: 10.1186/s13068-021-02068-9
Products & Services: Codon Optimization   
A novel DNA platform designed for vaccine use with high transgene expression and immunogenicity
Authors: George Giorgi Babuadze, Jose Echanove, Claude Lamarre, Marc-Antoine deLaVega, Hugues Fausther-Bovendo, Trina Racine, Alejandro M Gomez, Hiva Azizi, Mathew Wade, Robert Kozak, Gary P Kobinger
Journal: Vaccine
PubMed ID: 34774358
Doi: 10.1016/j.vaccine.2021.10.008
Products & Services: Catalog Antibody   
Insulin-activated store-operated Ca entry via Orai1 induces podocyte actin remodeling and causes proteinuria
Authors: Ji-Hee Kim, Kyu-Hee Hwang, Bao T N Dang, Minseob Eom, In Deok Kong, Yousang Gwack, Seyoung Yu, Heon Yung Gee, Lutz Birnbaumer, Kyu-Sang Park, Seung-Kuy Cha
Journal: Nat Commun
PubMed ID: 34764278
Doi: 10.1038/s41467-021-26900-w
Products & Services: Catalog Antibody   
Diagnosis of Streptococcus pneumoniae infection using circulating antibody secreting cells
Authors: Shuya Kyu, Richard P Ramonell, Merin Kuruvilla, Colleen S Kraft, Yun F Wang, Ann R Falsey, Edward E Walsh, John L Daiss, Simon Paulos, Gowrisankar Rajam, Hao Wu, Srinivasan Velusamy, F Eun-Hyung Lee
Journal: PLoS ONE
PubMed ID: 34767590
Doi: 10.1371/journal.pone.0259644
Products & Services: Bacterial Expression   
Extended cleavage specificity of a Chinese alligator granzyme B homologue, a strict Glu-ase in contrast to the mammalian Asp-ases
Authors: Jinhye Ryu, Zhirong Fu, Srinivas Akula, Anna-Karin Olsson, Lars Hellman
Journal: Dev Comp Immunol
PubMed ID: 34826501
Doi: 10.1016/j.dci.2021.104324
Products & Services: Gene Synthesis   
New and efficient purification process for recombinant human insulin produced in Escherichia coli
Authors: Yin Yin Siew, Amrita Rai, Han Bin Pek, Dave Siak-Wei Ow, Wei Zhang
Journal: Appl Microbiol Biotechnol
PubMed ID: 34821966
Doi: 10.1007/s00253-021-11697-x
Products & Services: Bacterial Expression   
Improved the Activity of Phosphite Dehydrogenase and its Application in Plant Biotechnology
Authors: Tongtong Liu, Lili Yuan, Suren Deng, Xiangxian Zhang, Hongmei Cai, Guangda Ding, Fangsen Xu, Lei Shi, Gaobing Wu, Chuang Wang
Journal: Front Bioeng Biotechnol
PubMed ID: 34900961
Doi: 10.3389/fbioe.2021.764188
Products & Services: Gene Synthesis   
Recombinant Bacillus subtilis flagellin Hag is a potent immunostimulant with reduced proinflammatory properties compared to Salmonella enterica serovar Typhimurium FljB
Authors: Mélanie Côté-Cyr, Laurie Gauthier, Ximena Zottig, Steve Bourgault, Denis Archambault
Journal: Vaccine
PubMed ID: 34844822
Doi: 10.1016/j.vaccine.2021.11.049
Products & Services: Gene Synthesis   
Enhancing the resilience of transgenic cotton for insect resistance
Authors: Mohsin Shad, Aneela Yasmeen, Saira Azam, Allah Bakhsh, Ayesha Latif, Naila Shahid, Sahar Sadaqat, Abdul Qayyum Rao, Ahmad Ali Shahid
Journal: Mol Biol Rep
PubMed ID: 34839448
Doi: 10.1007/s11033-021-06972-z
Inhibition of SGLT1 alleviates the glycemic variability-induced cardiac fibrosisvia inhibiting activations of macrophage and cardiac fibroblast
Authors: Weihua Wu, Qian Chai, Ziying Zhang
Journal: MOL CELL BIOL
PubMed ID: 34842443
Doi: 10.1128/MCB.00282-21
Products & Services: Custom DNA/RNA Oligos   
Genetic manipulation of trehalose-6-phosphate synthase results in changes in the soluble sugar profile in transgenic sugarcane stems
Authors: Casey Gabriel, Jean-Jacque Fernhout, Franziska Fichtner, Regina Feil, John E Lunn, Jens Kossmann, James R Lloyd, Christell van der Vyver
Journal: Plant Direct
PubMed ID: 34765864
Doi: 10.1002/pld3.358
Products & Services: Gene Synthesis   
MmpL3, the trehalose monomycolate transporter, is stable in solution in several detergents and can be reconstituted into peptidiscs
Authors: Kien Lam Ung, Husam Alsarraf, Laurent Kremer, Mickaël Blaise
Journal: Protein Expr Purif
PubMed ID: 34767949
Doi: 10.1016/j.pep.2021.106014
Products & Services: Peptide Synthesis   
A SYBR Green-based real-time RT-PCR assay to differentiate the H1N1 influenza virus lineages
Authors: Yulin Cong, Yixue Sun, Xiaoyu Deng, Haiying Yu, Xiaohuan Lian, Yanlong Cong
Journal: J Virol Methods
PubMed ID: 34848281
Doi: 10.1016/j.jviromet.2021.114387
Products & Services: Gene Synthesis   
ELAPOR1 is a secretory granule maturation-promoting factor that is lost during paligenosis
Authors: Charles J Cho, Dongkook Park, Jason C Mills
Journal: Am J Physiol Gastrointest Liver Physiol
PubMed ID: 34816763
Doi: 10.1152/ajpgi.00246.2021
Products & Services: Gene Synthesis   

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