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A phage parasite deploys a nicking nuclease effector to inhibit viral host replication

Authors: Kristen N LeGault, Zachary K Barth, Peter DePaola, Kimberley D Seed

Journal: Nucleic Acids Res

PubMed ID: 35066583

Doi: 10.1093/nar/gkac002

Products & Services: Gene Synthesis

A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy

Authors: Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot

Journal: Theranostics

PubMed ID: 34976196

Doi: 10.7150/thno.63744

Products & Services: Gene Synthesis

Introducing an Artificial Deazaflavin Cofactor in and

Authors: Misun Lee, Jeroen Drenth, Milos Trajkovic, René M de Jong, Marco W Fraaije

Journal: ACS Synth Biol

PubMed ID: 35044755

Doi: 10.1021/acssynbio.1c00552

Products & Services: Bacterial Expression

High level production of stable human serum albumin in Pichia pastoris and characterization of the recombinant product

Authors: Nitu Maity, Avijeet S Jaswal, Ashwani Gautam, Vikram Sahai, Saroj Mishra

Journal: Bioprocess Biosyst Eng

PubMed ID: 34999948

Doi: 10.1007/s00449-021-02670-z

Products & Services: PCR Cloning and Subcloning

theLiTE™: A Screening Platform to Identify Compounds that Reinforce Tight Junctions

Authors: Teresa Lopes Gomes, Virgínia de Oliveira-Marques, Richard John Hampson, António Jacinto, Luciana Vieira de Moraes, Rui Gonçalo Martinho

Journal: Front Pharmacol

PubMed ID: 35069190

Doi: 10.3389/fphar.2021.752787

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Characterization of male-biased fatty acid desaturase in the jewel wasp Nasonia vitripennis and its role in pheromone production

Authors: Jian-Qiu Cheng, Yu-Mei Tao, Jing Li, Yong-Zhuo Chen, Hao-Yuan Hu

Journal: J Exp Zool B Mol Dev Evol

PubMed ID: 34995007

Doi: 10.1002/jez.b.23120

Products & Services: Polyclonal Antibody Services

Porcine circovirus type 2 infection inhibits the activation of type I interferon signaling via capsid protein and host gC1qR

Authors: Zhenyu Wang, Jing Chen, Qiong-Ge Zhang, Kai Huang, Dan Ma, Qian Du, Dewen Tong, Yong Huang

Journal: Vet Microbiol

PubMed ID: 35085949

Doi: 10.1016/j.vetmic.2022.109354

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Hybridization chain reaction circuit-based electrochemiluminescent biosensor for SARS-cov-2 RdRp gene assay

Authors: Kai Zhang, Zhenqiang Fan, Yue Huang, Yuedi Ding, Minhao Xie, Minghe Wang

Journal: Talanta

PubMed ID: 34998144

Doi: 10.1016/j.talanta.2022.123207

Products & Services: Gene Synthesis

Self-Assembly of Flagellin into Immunostimulatory Ring-like Nanostructures as an Antigen Delivery System

Authors: Mélanie Côté-Cyr, Ximena Zottig, Laurie Gauthier, Denis Archambault, Steve Bourgault

Journal: ACS Biomater Sci Eng

PubMed ID: 35080372

Doi: 10.1021/acsbiomaterials.1c01332

Products & Services: Gene Synthesis

SARS-CoV-2 Seroprevalence Among Whole Blood Donors During First Wave of Covid-19 Pandemic in India

Authors: Srinivasa Rao Chunchu, Ushasree Ravula, Vikram Kumar Gente, Srinivas Bacchu, S Pandu Ranga Rao, Srujaleswari Mooli

Journal: Indian J Hematol Blood Transfus

PubMed ID: 35125705

Doi: 10.1007/s12288-021-01512-y

Products & Services: Catalog Antibody

Heterologous immunization with BNT162b2 followed by mRNA-1273 in dialysis patients: seroconversion and presence of neutralizing antibodies

Authors: Niko Kohmer, Holger F Rabenau, Sandra Ciesek, Bernhard K Krämer, Uwe Göttmann, Christine Keller, Daniela Rose, Carsten Blume, Michael Thomas, Alexander Lammert, Anne Lammert

Journal: Nephrol Dial Transplant

PubMed ID: 35099023

Doi: 10.1093/ndt/gfac018

Products & Services: Catalog Antibody

Circular RNA circFGFR1 Functions as an Oncogene in Glioblastoma Cells through Sponging to hsa-miR-224-5p

Authors: Qian Zhang, Shan Chen, Yingwei Zhen, Peng Gao, Zhenyu Zhang, Hao Guo, Yong Wang

Journal: J Immunol Res

PubMed ID: 35059468

Doi: 10.1155/2022/7990251

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Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold

Authors: Yaw Bia Tan, Laura Sandra Lello, Xin Liu, Yee-Song Law, Congbao Kang, Julien Lescar, Jie Zheng, Andres Merits, Dahai Luo

Journal: Nucleic Acids Res

PubMed ID: 35037043

Doi: 10.1093/nar/gkab1302

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Porphyromonas gingivalis infection promotes inflammation via inhibition of the AhR signalling pathway in periodontitis

Authors: Ting Hao, Rui Zhang, Tian Zhao, Juan Wu, Wai Keung Leung, Jie Yang, Weibin Sun

Journal: Cell Prolif

PubMed ID: 36446468

Doi: 10.1111/cpr.13364

Products & Services: Proteins, Expression, Isolation and Analysis

Full-length recombinant antibodies from : production, characterization, effector function (Fc) engineering, and clinical evaluation

Authors:

Journal: MAbs

PubMed ID: 36018829

Doi: 10.1080/19420862.2022.2111748

Products & Services: Gene Synthesis

Circular RNA circRNA_0082835 promotes progression and lymphatic metastasis of primary melanoma by sponging microRNA miRNA-429

Authors: Yute Sun, Zuoqiong Hou, Binlin Luo, Chujun Li, Jinfang Liu, Jianlan Liu, Jian Tang, Gang Yao

Journal: Bioengineered

PubMed ID: 34288815

Doi: 10.1080/21655979.2021.1953822

Products & Services: Proteins, Expression, Isolation and Analysis

Long non-coding RNA SNHG5 regulates ulcerative colitis via microRNA-375 / Janus kinase-2 axis

Authors: Hui Li, Ji Xuan, Wei Zhang, Zhentao An, Xinyu Fan, Min Lu, Yaozhou Tian

Journal: Bioengineered

PubMed ID: 34334085

Doi: 10.1080/21655979.2021.1953219

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a human antibody fragment directed against the alpha folate receptor as a promising molecule for targeted application

Authors: Nattihda Parakasikron, Chatchai Chaotham, Pithi Chanvorachote, Chanida Vinayanuwattikun, Visarut Buranasudja, Pornchanok Taweecheep, Kannika Khantasup

Journal: Drug Deliv

PubMed ID: 34236266

Doi: 10.1080/10717544.2021.1943055

Products & Services: Plasmid DNA Preparation

microRNA-26a shuttled by extracellular vesicles secreted from adipose-derived mesenchymal stem cells reduce neuronal damage through KLF9-mediated regulation of TRAF2/KLF2 axis

Authors: Zixin Hou, Ji Chen, Huan Yang, Xiaoling Hu, Fengrui Yang

Journal: Adipocyte

PubMed ID: 34311651

Doi: 10.1080/21623945.2021.1938829

Products & Services: Mutant Libraries

Mesenchymal Stem/Stromal Cells Overexpressing CXCR4 Revealed Enhanced Migration: A Lesson Learned from the Pathogenesis of WHIM Syndrome

Authors: Hamid Reza Bidkhori, Ahmad Reza Bahrami, Moein Farshchian, Asieh Heirani-Tabasi, Mahdi Mirahmadi, Halimeh Hasanzadeh, Naghmeh Ahmadiankia, Reza Faridhosseini, Mahtab Dastpak, Arezoo Gowhari Shabgah, Maryam M Matin

Journal: Cell Transplant

PubMed ID: 34807749

Doi: 10.1177/09636897211054498

Products & Services: Mutagenesis Services

Targeted therapy of irritable bowel syndrome with anti-inflammatory cytokines

Authors: Sunil Kumar, Priyanka Singh, Awanish Kumar

Journal: Clin J Gastroenterol

PubMed ID: 34862947

Doi: 10.1007/s12328-021-01555-8

Products & Services: Catalog Peptides

Long non-coding RNA H19 protects against intracerebral hemorrhage injuries via regulating microRNA-106b-5p/acyl-CoA synthetase long chain family member 4 axis

Authors: Bing Chen, Haoran Wang, Chenglin Lv, Chongdan Mao, Yuguang Cui

Journal: Bioengineered

PubMed ID: 34288826

Doi: 10.1080/21655979.2021.1951070

Products & Services: Gene Synthesis

Rapid test to assess the escape of SARS-CoV-2 variants of concern

Authors: Jacob T Heggestad, Rhett J Britton, David S Kinnamon, Simone A Wall, Daniel Y Joh, Angus M Hucknall, Lyra B Olson, Jack G Anderson, Anna Mazur, Cameron R Wolfe, Thomas H Oguin, Bruce A Sullenger, Thomas W Burke, Bryan D Kraft, Gregory D Sempowski, Christopher W Woods, Ashutosh Chilkoti

Journal: Sci Adv

PubMed ID: 34860546

Doi: 10.1126/sciadv.abl7682

Products & Services: Recombinant Proteins

Synthesis and anti-inflammatory activities of glycyrrhetinic acid derivatives containing disulfide bond

Authors: Qiuping Zhang, Yanni Wang, Zongyuan Wang, Eyad Abdulwhab Hamoud Mohammed, Quanyi Zhao, Dian He, Zhen Wang

Journal: Bioorg Chem

PubMed ID: 34902645

Doi: 10.1016/j.bioorg.2021.105542

Products & Services: Custom DNA/RNA Oligos

sp nov, a novel phenylacetic acid degrading bacterium isolated from sludge

Authors: Fa-Hu Pang, Hui-Ying Yang, Jie Sun, Xing Yu, Hao Zhang

Journal: Int J Syst Evol Microbiol

PubMed ID: 34878373

Doi: 10.1099/ijsem.0.005144

Products & Services: Custom DNA/RNA Oligos

KSHV transactivator-derived small peptide traps coactivators to attenuate MYC and inhibits leukemia and lymphoma cell growth

Authors: Michiko Shimoda, Yuanzhi Lyu, Kang-Hsin Wang, Ashish Kumar, Hiroki Miura, Joshua F Meckler, Ryan R Davis, Chanikarn Chantarasrivong, Chie Izumiya, Clifford G Tepper, Ken-Ichi Nakajima, Joseph Tuscano, Gustavo Barisone, Yoshihiro Izumiya

Journal: Commun Biol

PubMed ID: 34857874

Doi: 10.1038/s42003-021-02853-0

Products & Services: Peptide Synthesis

A unique flavoenzyme operates in ubiquinone biosynthesis in photosynthesis-related eukaryotes

Authors: Jing-Jing Xu, Xiao-Fan Zhang, Yan Jiang, Hang Fan, Jian-Xu Li, Chen-Yi Li, Qing Zhao, Lei Yang, Yong-Hong Hu, Cathie Martin, Xiao-Ya Chen

Journal: Sci Adv

PubMed ID: 34878842

Doi: 10.1126/sciadv.abl3594

Products & Services: Gene Synthesis

Population genetics of cycas necrotic stunt virus and the development of multiplex RT-PCR diagnostics

Authors: Cullen M Shaffer, David C Michener, Nastassia B Vlasava, Henry Chotkowski, Ioannis E Tzanetakis

Journal: Virus Res

PubMed ID: 34906655

Doi: 10.1016/j.virusres.2021.198655

Products & Services: Custom DNA/RNA Oligos

Novel reverse genetics of genotype I and III Japanese encephalitis viruses assembled through transformation associated recombination in yeast: The reporter viruses expressing a green fluorescent protein for the antiviral screening assay

Authors: Chenxi Li, Xuan Chen, Yanyang Zhou, Jingbo Hu, Xinjie Wang, Yanhua Li

Journal: Antiviral Res

PubMed ID: 34973281

Doi: 10.1016/j.antiviral.2021.105233

Products & Services: Gene Synthesis

ACE2-IgG1 fusions with improved and activity against SARS-CoV-2

Authors: Naoki Iwanaga, Laura Cooper, Lijun Rong, Nicholas J Maness, Brandon Beddingfield, Zhongnan Qin, Jackelyn Crabtree, Ralph A Tripp, Haoran Yang, Robert Blair, Sonia Jangra, Adolfo García-Sastre, Michael Schotsaert, Chandra Sruti, James E Robinson, Akhilesh Srivastava, Felix Rabito, Xuebin Qin, Jay K Kolls

Journal: iScience

PubMed ID: 34957381

Doi: 10.1016/j.isci.2021.103670

Products & Services: Gene Synthesis

Down-regulation of miR-340-5p promoted osteogenic differentiation through regulation of runt-related transcription factor-2 (RUNX2) in MC3T3-E1 cells

Authors: Xiaochen Wang, Yaochuan Mi, Wei He, Xiaona Hu, Shuo Yang, Lu Zhao, Yanyang Zhang, Binhong Wen

Journal: Bioengineered

PubMed ID: 33818278

Doi: 10.1080/21655979.2021.1905259

Products & Services: Recombinant Proteins

Implications of Quenching-to-Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye-Labeled Nanoparticles

Authors: Guangze Yang+ , Yun Liu+ , Yue Hui, Tengjisi, Dong Chen, David A. Weitz, and Chun-Xia Zhao

Journal: ANGEWANDTE CHEMIE

Doi: doi.org/10.1002/anie.202101730

Products & Services: Peptide Synthesis

Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin

Authors: Yan Wang, Zhiqiang Cheng, Jing Xu, Meina Lai, Liming Liu, Min Zuo, Lin Dang

Journal: Bioengineered

PubMed ID: 34076564

Doi: 10.1080/21655979.2021.1924544

Products & Services: Gene Synthesis

The arthrospore-related gene Acaxl2 is involved in cephalosporin C production in industrial Acremonium chrysogenum by the regulatory factors AcFKH1 and CPCR1

Authors: Yan Xu, Ling Liu, Zhen Chen, Xiwei Tian, Ju Chu

Journal: J Biotechnol

PubMed ID: 34954288

Doi: 10.1016/j.jbiotec.2021.12.011

Products & Services: Gene Synthesis

Physicochemical and molecular transformation of novel functional peptides from Baijiu

Authors: Wei Jia, An Du, Xiaojun Dong, Zibian Fan, Duimin Zhang, Ruihong Wang, Lin Shi

Journal: Food Chem

PubMed ID: 34954580

Doi: 10.1016/j.foodchem.2021.131894

Products & Services: Peptide Synthesis

WHO international standard for SARS-CoV-2 antibodies to determine markers of protection

Authors: Feng Zhu, Thomas Althaus, Chee Wah Tan, Alizée Costantini, Wan Ni Chia, Nguyen Van Vinh Chau, Le Van Tan, Giada Mattiuzzo, Nicola J Rose, Eric Voiglio, Lin-Fa Wang

Journal: Lancet Microbe

PubMed ID: 34901897

Doi: 10.1016/S2666-5247(21)00307-4

Products & Services: Protein Reagents and Products

Plasmonically Enhanced Ultrasensitive Epitope-Specific Serologic Assay for COVID-19

Authors: Zheyu Wang, Jeremiah J Morrissey, Lin Liu, Yixuan Wang, Qingjun Zhou, Rajesh R Naik, Srikanth Singamaneni

Journal: Anal Chem

PubMed ID: 34935364

Doi: 10.1021/acs.analchem.1c03676

Products & Services: Peptide Synthesis

Novel nanostructure-coupled biosensor platform for one-step high-throughput quantification of serum neutralizing antibody after COVID-19 vaccination

Authors: Liping Huang, Ying Li, Changyou Luo, Youqian Chen, Nadia Touil, Hicham-El Annaz, Shaoqi Zeng, Tang Dang, Jiawei Liang, Wenjun Hu, Hao Xu, Jiasheng Tu, Lin Wang, Yan Shen, Gang L Liu

Journal: Biosens Bioelectron

PubMed ID: 34920226

Doi: 10.1016/j.bios.2021.113868

Products & Services: Protein Reagents and Products

A Stabilized, Monomeric, Receptor Binding Domain Elicits High-Titer Neutralizing Antibodies Against All SARS-CoV-2 Variants of Concern

Authors: Shahbaz Ahmed, Mohammad Suhail Khan, Savitha Gayathri, Randhir Singh, Sahil Kumar, Unnatiben Rajeshbhai Patel, Sameer Kumar Malladi, Raju S Rajmani, Petrus Jansen van Vuren, Shane Riddell, Sarah Goldie, Nidhi Girish, Poorvi Reddy, Aditya Upadhyaya, Suman Pandey, Samreen Siddiqui, Akansha Tyagi, Sujeet Jha, Rajesh Pandey, Oyahida Khatun, Rohan Narayan, Shashank Tripathi, Alexander J McAuley, Nagendrakumar Balasubramanian Singanallur, Seshadri S Vasan, Rajesh P Ringe, Raghavan Varadarajan

Journal: Front Immunol

PubMed ID: 34956193

Doi: 10.3389/fimmu.2021.765211

Products & Services: Gene Synthesis

Dynamic Distribution of HIG2A between the Mitochondria and the Nucleus in Response to Hypoxia and Oxidative Stress

Authors: Celia Salazar, Miriam Barros, Alvaro A Elorza, Lina María Ruiz

Journal: Int J Mol Sci

PubMed ID: 35008815

Doi: 10.3390/ijms23010389

Products & Services: Plasmid DNA Preparation

Glycoside Hydrolase family 30 harbors fungal subfamilies with distinct polysaccharide specificities

Authors: Xinxin Li, Dimitrios Kouzounis, Mirjam A Kabel, Ronald P de Vries, Adiphol Dilokpimol

Journal: N Biotechnol

PubMed ID: 34952234

Doi: 10.1016/j.nbt.2021.12.004

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Cloning, Expression and Inhibitory Effects on Lewis Lung Carcinoma Cells of rAj-Tspin from Sea Cucumber ()

Authors: Rong Qiao, Rong Xiao, Zhong Chen, Jingwei Jiang, Chenghua Yuan, Shuxiang Ning, Jihong Wang, Zunchun Zhou

Journal: Molecules

PubMed ID: 35011462

Doi: 10.3390/molecules27010229

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Progressing Ultragreen, Energy-Efficient Biobased Depolymerization of Poly(ethylene terephthalate) via Microwave-Assisted Green Deep Eutectic Solvent and Enzymatic Treatment

Authors: Olivia A Attallah, Muhammad Azeem, Efstratios Nikolaivits, Evangelos Topakas, Margaret Brennan Fournet

Journal: Polymers (Basel)

PubMed ID: 35012131

Doi: 10.3390/polym14010109

Products & Services: Bacterial Expression

A de novo ACTB gene pathogenic variant in identical twins with phenotypic variation for hydrops and jejunal atresia

Authors: Kristina Sibbin, Patrick Yap, Denis Nyaga, Raoul Heller, Stephen Evans, Kate Strachan, Salam Alburaiky, Han M Alex Nguyen, Sylvie Hermann-Le Denmat, Austen R D Ganley, Justin M O'Sullivan, Frank H Bloomfield

Journal: Am J Med Genet A

PubMed ID: 34970864

Doi: 10.1002/ajmg.a.62631

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Humoral and cellular immune responses to the SARS-CoV-2 BNT162b2 vaccine among a cohort of solid organ transplant recipients and healthy controls

Authors: Ahmad Yanis, Zaid Haddadin, Andrew J Spieker, Danya Waqfi, Danielle A Rankin, Rana Talj, Lora Thomas, Kelly A Birdwell, Lauren Ezzell, Marcia Blair, Joan Eason, Rebekkah Varjabedian, Christian M Warren, Cynthia H Nochowicz, Eric C Olson, Joshua D Simmons, Sandra Yoder, Madeline Guy, Isaac Thomsen, James D Chappell, Spyros A Kalams, Natasha B Halasa

Journal: Transpl Infect Dis

PubMed ID: 34905653

Doi: 10.1111/tid.13772

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Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile

Authors: Daniel Rehling, Emma Rose Scaletti, Inna Rozman Grinberg, Daniel Lundin, Margareta Sahlin, Anders Hofer, Britt-Marie Sjöberg, Pål Stenmark

Journal: Biochemistry

PubMed ID: 34941255

Doi: 10.1021/acs.biochem.1c00503

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Isolation of TCR genes with tumor-killing activity from tumor-infiltrating and circulating lymphocytes in a tumor rejection cynomolgus macaque model

Authors: Koji Terada, Kenta Kondo, Hirohito Ishigaki, Ayaka Nagashima, Hiroki Satooka, Seiji Nagano, Kyoko Masuda, Teruhisa Kawamura, Takako Hirata, Kazumasa Ogasawara, Yasushi Itoh, Hiroshi Kawamoto, Yasutoshi Agata

Journal: Mol Ther Oncolytics

PubMed ID: 35024435

Doi: 10.1016/j.omto.2021.12.003

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A Highly Conserved Peptide Vaccine Candidate Activates Both Humoral and Cellular Immunity Against SARS-CoV-2 Variant Strains

Authors: Fengxia Gao, Jingjing Huang, Tingting Li, Chao Hu, Meiying Shen, Song Mu, Feiyang Luo, Shuyi Song, Yanan Hao, Wang Wang, Xiaojian Han, Chen Qian, Yingming Wang, Ruixin Wu, Luo Li, Shenglong Li, Aishun Jin

Journal: Front Immunol

PubMed ID: 34950151

Doi: 10.3389/fimmu.2021.789905

Products & Services: Proteins, Expression, Isolation and Analysis

LncRNA FOXP4-AS1 Promotes the Progression of Esophageal Squamous Cell Carcinoma by Interacting With MLL2/H3K4me3 to Upregulate FOXP4

Authors: Yunfeng Niu, Gaoyan Wang, Yan Li, Wei Guo, Yanli Guo, Zhiming Dong

Journal: Front Oncol

PubMed ID: 34970490

Doi: 10.3389/fonc.2021.773864

Products & Services: Plasmid DNA Preparation

-Encoding Protein Is the Only Chemoreceptor That Regulates Chemoattraction toward the Broad Antibacterial Agent Formic Acid

Authors: Hao Wang, Mengqi Zhang, Yujuan Xu, Renjie Zong, Nan Xu, Minliang Guo

Journal: Biology (Basel)

PubMed ID: 34943260

Doi: 10.3390/biology10121345

Products & Services: Polyclonal Antibody Services

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