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Overcoming tumor heterogeneity by ex vivo arming of T cells using multiple bispecific antibodies
Authors: Jeong A Park, Nai-Kong V Cheung
Journal: J Immunother Cancer
PubMed ID: 35086947
Doi: 10.1136/jitc-2021-003771
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Fukutin regulates tau phosphorylation and synaptic function: Novel properties of fukutin in neurons
Authors: Ryota Tsukui, Tomoko Yamamoto, Yukinori Okamura, Yoichiro Kato, Noriyuki Shibata
Journal: Neuropathology
PubMed ID: 35026860
Doi: 10.1111/neup.12797
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Backbone NMR assignment of the nucleotide binding domain of the Bacillus subtilis ABC multidrug transporter BmrA in the post-hydrolysis state
Authors: Victor Hugo Pérez Carrillo, Dania Rose-Sperling, Mai Anh Tran, Christoph Wiedemann, Ute A Hellmich
Journal: Biomol NMR Assign
PubMed ID: 34988902
Doi: 10.1007/s12104-021-10063-2
Products & Services: Gene Synthesis   
Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase
Authors: Tasvi Daya, Olamide Jeje, Reabetswe Maake, Chinyere Aloke, Thandeka Khoza, Ikechukwu Achilonu
Journal: Protein J
PubMed ID: 35083643
Doi: 10.1007/s10930-021-10037-2
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Homologous PB1 gene promotes the replication efficiency of avian influenza H7N4 candidate vaccine virus
Authors: Liqi Liu, Zi Li, Jianfang Zhou, Jia Liu, Xiyan Li, Weijuan Huang, Ning Xiao, Dayan Wang
Journal: Influenza Other Respir Viruses
PubMed ID: 35037399
Doi: 10.1111/irv.12954
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Formation of β-Strand Oligomers of Antimicrobial Peptide Magainin 2 Contributes to Disruption of Phospholipid Membrane
Authors: Munehiro Kumashiro, Ryoga Tsuji, Shoma Suenaga, Koichi Matsuo
Journal: Membranes (Basel)
PubMed ID: 35207051
Doi: 10.3390/membranes12020131
Products & Services: Peptide Synthesis   
Inhibiting L1CAM Reverses Cisplatin Resistance of Triple Negative Breast Cancer Cells by Blocking AKT Signaling Pathway
Authors: Lu-Yao Zhang, Zhi-Xin Shen, Lu Guo
Journal: Cancer Invest
PubMed ID: 35040385
Doi: 10.1080/07357907.2021.2016801
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Formation of β-Strand Oligomers of Antimicrobial Peptide Magainin 2 Contributes to Disruption of Phospholipid Membrane
Authors: Munehiro Kumashiro, Ryoga Tsuji, Shoma Suenaga, Koichi Matsuo
Journal: Membranes (Basel)
PubMed ID: 35207051
Doi: 10.3390/membranes12020131
Products & Services: Peptide Synthesis   
Circ_HECTD1 regulates cerebral ischemia injury via mechanisms involving the regulation of let-7c-5p/ROCK1 axis
Authors: Qian Guo, Tingting Guo, Yuanyuan Sun, Tianrong Chen
Journal: Neuroreport
PubMed ID: 34874325
Doi: 10.1097/WNR.0000000000001743
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Hempseed () Peptides WVSPLAGRT and IGFLIIWV Exert Anti-inflammatory Activity in the LPS-Stimulated Human Hepatic Cell Line
Authors: Ivan Cruz-Chamorro, Guillermo Santos-Sánchez, Carlotta Bollati, Martina Bartolomei, Jianqiang Li, Anna Arnoldi, Carmen Lammi
Journal: J Agric Food Chem
PubMed ID: 35007086
Doi: 10.1021/acs.jafc.1c07520
Bio-nanocapsules for oriented immobilization of DNA aptamers on aptasensors
Authors: Masumi Iijima, Yuki Yamada, Hideo Nakano, Tsutomu Nakayama, Shun'ichi Kuroda
Journal: Analyst
PubMed ID: 35023508
Doi: 10.1039/d1an02278d
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The extracellular Ero1α/PDI electron transport system regulates platelet function by increasing glutathione reduction potential
Authors: Lu Wang, Xi Wang, Xiying Lv, Qiushuo Jin, Hongcai Shang, Chih-Chen Wang, Lei Wang
Journal: Redox Biol
PubMed ID: 35077997
Doi: 10.1016/j.redox.2022.102244
Products & Services: Peptide Synthesis   
Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence
Authors: Stefano Perni, Kurt Beam
Journal: J Gen Physiol
PubMed ID: 35089322
Doi: 10.1085/jgp.202113024
Products & Services: Mammalian Expression   
Novel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral Roles
Authors: Yueyue Duan, Liyan Cao, Cong Yuan, Xuepeng Suo, Xiangyu Kong, Yulong Gao, Xiangtong Li, Haixue Zheng, Xiaomei Wang, Qi Wang
Journal: MBio
PubMed ID: 35038897
Doi: 10.1128/mbio.03287-21
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Conditional Alternative Protein Splicing Promoted by Inteins from
Authors: Vaishnavi R Yalala, Abigeal K Lynch, Kenneth V Mills
Journal: Biochemistry
PubMed ID: 35073064
Doi: 10.1021/acs.biochem.1c00788
Products & Services: Plasmid DNA Preparation   
Bioengineered pseudovirus nanoparticles displaying the HA1 antigens of influenza viruses for enhanced immunogenicity
Authors: Ming Xia, Md Rejaul Hoq, Pengwei Huang, Wen Jiang, Xi Jiang, Ming Tan
Journal: Nano Res
PubMed ID: 35106126
Doi: 10.1007/s12274-021-4011-x
Products & Services: Molecular Biology Tools   
Trichodysplasia spinulosa polyomavirus small T antigen synergistically modulates S6 protein translation and DNA damage response pathways to shape host cell environment
Authors: Deepika Narayanan, Danyal Tahseen, Brooke R Bartley, Stephen A Moore, Rebecca Simonette, Peter L Rady, Stephen K Tyring
Journal: Virus Genes
PubMed ID: 35000075
Doi: 10.1007/s11262-021-01880-7
Bioengineered pseudovirus nanoparticles displaying the HA1 antigens of influenza viruses for enhanced immunogenicity
Authors: Ming Xia, Md Rejaul Hoq, Pengwei Huang, Wen Jiang, Xi Jiang, Ming Tan
Journal: Nano Res
PubMed ID: 35106126
Doi: 10.1007/s12274-021-4011-x
Products & Services: Molecular Biology Tools   
HOTAIR Induces the Downregulation of miR-200 Family Members in Gastric Cancer Cell Lines
Authors: Fatemeh Bossaghzadeh, Mohammadreza Hajjari, Abdolkarim Sheikhi, Iman Salahshourifar, Shiva Irani
Journal: Iran Biomed J
PubMed ID: 34923813
Doi: 10.52547/ibj.26.1.77
Products & Services: Molecular Biology Tools   
Formation of Calprotectin-Derived Peptides in the Airways of Children with Cystic Fibrosis
Authors: Teagan S Edwards, Nina Dickerhof, Nicholas J Magon, Louise N Paton, Peter D Sly, Anthony J Kettle
Journal: J Immunol
PubMed ID: 35046105
Doi: 10.4049/jimmunol.2001017
Products & Services: Peptide Modifications   
Genome-Wide Identification and Expression Profile Analysis of the SnRK2 Gene Family in Nicotiana tabacum
Authors: Jinghao Li, Jiangyu Song, Changjun Li, Juntao Ma, Jiawang Liu, Xiaowei Zhu, Jingchao Li, Fan He, Chao Yang
Journal: Biochem Genet
PubMed ID: 35048221
Doi: 10.1007/s10528-021-10170-8
Products & Services: Protein Tools   
Development of an enzymatic method for the evaluation of protein deposition on contact lenses
Authors: Simin Masoudi, Mark Willcox
Journal: Biofouling
PubMed ID: 35016572
Doi: 10.1080/08927014.2021.2019225
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A Micrarchaeon isolate is covered by a proteinaceous S-Layer
Authors: Sabrina Gfrerer, Dennis Winkler, Julia Novion Ducassou, Yohann Couté, Reinhard Rachel, Johannes Gescher
Journal: Appl Environ Microbiol
PubMed ID: 35020453
Doi: 10.1128/AEM.01553-21
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A Micrarchaeon isolate is covered by a proteinaceous S-Layer
Authors: Sabrina Gfrerer, Dennis Winkler, Julia Novion Ducassou, Yohann Couté, Reinhard Rachel, Johannes Gescher
Journal: Appl Environ Microbiol
PubMed ID: 35020453
Doi: 10.1128/AEM.01553-21
Products & Services: Catalog Antibody   
The Novel microRNA Rno-miR-686-3p Is Associated with the Ischaemic Penumbra
Authors: Wei Wang, Jin-Pin Li, Jing-Li Liu
Journal: Eur Neurol
PubMed ID: 35100587
Doi: 10.1159/000521491
Products & Services: DNA Sequencing   
Survey of SARS-CoV-2 in dogs and cats in high-risk areas during the second wave of COVID-19 outbreak, Thailand
Authors: Waleemas Jairak, Kamonpan Charoenkul, Ekkapat Chamsai, Kitikhun Udom, Supassama Chaiyawong, Aphinya Hangsawek, Suchart Waenkaew, Anek Mungaomklang, Ratanaporn Tangwangvivat, Alongkorn Amonsin
Journal: Zoonoses Public Health
PubMed ID: 34981900
Doi: 10.1111/zph.12907
Safety and Immunogenicity of the Third Booster Dose with Inactivated, Viral Vector, and mRNA COVID-19 Vaccines in Fully Immunized Healthy Adults with Inactivated Vaccine
Authors: Sitthichai Kanokudom, Suvichada Assawakosri, Nungruthai Suntronwong, Chompoonut Auphimai, Pornjarim Nilyanimit, Preeyaporn Vichaiwattana, Thanunrat Thongmee, Ritthideach Yorsaeng, Donchida Srimuan, Thaksaporn Thatsanatorn, Sirapa Klinfueng, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Sittisak Honsawek, Yong Poovorawan
Journal: Vaccines (Basel)
PubMed ID: 35062747
Doi: 10.3390/vaccines10010086
Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway
Authors: Veronica Mutti, Federica Bono, Zaira Tomasoni, Leonardo Bontempi, Adele Guglielmi, Silvia Bolognin, Jens C Schwamborn, Cristina Missale, Chiara Fiorentini
Journal: Mol Neurobiol
PubMed ID: 35044626
Doi: 10.1007/s12035-022-02748-z
Products & Services: Gene Synthesis   
In vivo HSC gene therapy for SARS-CoV2 infection using a decoy receptor
Authors: Hongjie Wang, Chang Li, Adebimpe Obadan, Hannah Frizzell, Tien-Ying Hsiang, Sucheol Gil, Audrey Germond, Connie Fountain, Audrey Baldessari, Steve Roffler, Hans-Peter Kiem, Deborah Fuller, Andre Lieber
Journal: Hum Gene Ther
PubMed ID: 35057635
Doi: 10.1089/hum.2021.295
Products & Services: Recombinant Antibody Expression   
Development and Clinical Validation of a Potential Penside Colorimetric Loop-Mediated Isothermal Amplification Assay of Porcine Circovirus Type 3
Authors: Jie Zhang, Miaomiao Li, Yunwen Ou, Danian Chen, Yaozhong Ding, Weibing Zhang, Yanjun Li, Qian Hou, Xiaoyun Li, Luoyi Zhou, Katarzyna Podgorska, Alexei D Zaberezhny, Anna Szczotka-Bochniarz, Yongsheng Liu, Yang Wang
Journal: Front Microbiol
PubMed ID: 35095787
Doi: 10.3389/fmicb.2021.758064
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Optimization of loop-mediated isothermal amplification (LAMP) assay for robust visualization in SARS-CoV-2 and emerging variants diagnosis
Authors: Zhen Luo, Chunhong Ye, Heng Xiao, Jialing Yin, Yicong Liang, Zhihui Ruan, Danju Luo, Daolong Gao, Qiuping Tan, Yongkui Li, Qiwei Zhang, Weiyong Liu, Jianguo Wu
Journal: Chem Eng Sci
PubMed ID: 35043022
Doi: 10.1016/j.ces.2022.117430
Products & Services: Gene Synthesis   
miR-505 inhibits replication of Borna disease virus 1 via inhibition of HMGB1-mediated autophagy
Authors: Yujie Guo, Xiaoyan Xu, Tian Tang, Lin Sun, Xiong Zhang, Xia Shen, Dan Li, Lixin Wang, Libo Zhao, Peng Xie
Journal: J Gen Virol
PubMed ID: 35060474
Doi: 10.1099/jgv.0.001713
Products & Services: Catalog Antibody   
Prognostic significance of a complement factor H autoantibody in early stage NSCLC
Authors: Elizabeth B Gottlin, Michael J Campa, Rikesh Gandhi, Ryan T Bushey, James E Herndon, Edward F Patz
Journal: Cancer Biomark
PubMed ID: 35068447
Doi: 10.3233/CBM-210355
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An AAV vaccine targeting the RBD of the SARS-CoV-2 S protein induces effective neutralizing antibody titers in mice and canines
Authors: Fei Liu, Canbin Feng, Shiqi Xu, Qiang Wu, Jian Tang, Yan Chen, Ruisheng Xu, Fuliang Chen, Ni Gao, Zhengzheng Xu, Shihui Gu, Yang Lan, Haibo Zhou, Xinde Hu, Xiaojing Wang
Journal: Vaccine
PubMed ID: 35094871
Doi: 10.1016/j.vaccine.2022.01.030
Products & Services: Mammalian Expression   
ADAM17 regulates the proliferation and extracellular matrix of keloid fibroblasts by mediating the EGFR/ERK signaling pathway
Authors: Xin Le, You-Fen Fan
Journal: J Plast Surg Hand Surg
PubMed ID: 34978504
Doi: 10.1080/2000656X.2021.2017944
Products & Services: Gene Synthesis   
Downregulation of estrogen receptor-α36 expression attenuates metastasis of hepatocellular carcinoma cells
Authors: Ruobing Wang, Jiaming Chen, Haiyan Yu, Zhixuan Wei, Min Ma, Xueyan Ye, Weiqi Wu, Hongfei Chen, Zhengqi Fu
Journal: Environ Toxicol
PubMed ID: 35044086
Doi: 10.1002/tox.23469
Products & Services: Stable Cell Lines   
Waning antibody levels after COVID-19 vaccination with mRNA Comirnaty and inactivated CoronaVac vaccines in blood donors, Hong Kong, April 2020 to October 2021
Authors: Shirley Ll Kwok, Samuel Ms Cheng, Jennifer Ns Leung, Kathy Leung, Cheuk-Kwong Lee, Js Malik Peiris, Joseph T Wu
Journal: Euro Surveill
PubMed ID: 35027105
Doi: 10.2807/1560-7917.ES.2022.27.2.2101197
Self-assembling ferritin nanoparticles coupled with linear sequences from canine distemper virus haemagglutinin protein elicit robust immune responses
Authors: Bo Wang, Shuang Li, Yongbo Qiao, Yu Fu, Jiaojiao Nie, Shun Jiang, Xin Yao, Yi Pan, Linye Zhao, Congmei Wu, Yuhua Shi, Yuhe Yin, Yaming Shan
Journal: J Nanobiotechnology
PubMed ID: 35012571
Doi: 10.1186/s12951-021-01229-0
Products & Services: Codon Optimization   
K-edge anomalous SAXS for protein solution structure modeling
Authors: Karman Virk, Kento Yonezawa, Komal Choukate, Lucky Singh, Nobutaka Shimizu, Barnali Chaudhuri
Journal: Acta Crystallogr D Struct Biol
PubMed ID: 35102886
Doi: 10.1107/S205979832101247X
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Genome-wide identification and expression pattern analysis of the TCP transcription factor family in
Authors: Li Yu, Qiangwen Chen, Jiarui Zheng, Feng Xu, Jiabao Ye, Weiwei Zhang, Yongling Liao, Xiaoyan Yang
Journal: Plant Signal Behav
PubMed ID: 35068346
Doi: 10.1080/15592324.2021.1994248
Products & Services: Protein Tools   
Efficacy of an ALDH peptide-based dendritic cell vaccine targeting cancer stem cells
Authors: Fei Liao, Jing Zhang, Yangyang Hu, Alireza Hassani Najafabadi, James J Moon, Max S Wicha, Bashir Kaspo, Joel Whitfield, Alfred E Chang, Qiao Li
Journal: Cancer Immunol Immunother
PubMed ID: 35098344
Doi: 10.1007/s00262-021-03129-6
Products & Services: Recombinant Proteins   
miR-223 in exosomes from bone marrow mesenchymal stem cells ameliorates rheumatoid arthritis via downregulation of NLRP3 expression in macrophages
Authors: Ying Huang, Daomin Lu, Wukai Ma, Jun Liu, Qiaoyi Ning, Fang Tang, Long Li
Journal: Mol Immunol
PubMed ID: 35042119
Doi: 10.1016/j.molimm.2022.01.002
Products & Services: Gene Synthesis   
A Pig-a conditional knock-out mice model mediated by Vav-iCre: stable GPI-deficient and mild hemolysis
Authors: Yingying Chen, Hui Liu, Lijie Zeng, Liyan Li, Dan Lu, Zhaoyun Liu, Rong Fu
Journal: Exp Hematol Oncol
PubMed ID: 35033195
Doi: 10.1186/s40164-022-00254-5
A Pig-a conditional knock-out mice model mediated by Vav-iCre: stable GPI-deficient and mild hemolysis
Authors: Yingying Chen, Hui Liu, Lijie Zeng, Liyan Li, Dan Lu, Zhaoyun Liu, Rong Fu
Journal: Exp Hematol Oncol
PubMed ID: 35033195
Doi: 10.1186/s40164-022-00254-5
Bioinformatics based discovery of new keratinases in protease family M36
Authors: Jingwen Qiu, Kristian Barrett, Casper Wilkens, Anne S Meyer
Journal: N Biotechnol
PubMed ID: 35032710
Doi: 10.1016/j.nbt.2022.01.004
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Clinical Potential of lncRNA PPP1R26-AS1 in Breast Cancer and Its Contribution to Cancer Progression
Authors: Shuping Zhou, Shaoli Zhang, Hui Zhang, Junxia Ma, Huangzhen Dai, Lili Qu, Meixiang Zhou
Journal: Mol Biotechnol
PubMed ID: 35064892
Doi: 10.1007/s12033-022-00452-w
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Antibody Responses after SARS-CoV-2 Vaccination in Patients with Liver Diseases
Authors: Athanasios-Dimitrios Bakasis, Kleopatra Bitzogli, Dimitrios Mouziouras, Abraham Pouliakis, Maria Roumpoutsou, Andreas V Goules, Theodoros Androutsakos
Journal: Viruses
PubMed ID: 35215801
Doi: 10.3390/v14020207
Antibody Responses after SARS-CoV-2 Vaccination in Patients with Liver Diseases
Authors: Athanasios-Dimitrios Bakasis, Kleopatra Bitzogli, Dimitrios Mouziouras, Abraham Pouliakis, Maria Roumpoutsou, Andreas V Goules, Theodoros Androutsakos
Journal: Viruses
PubMed ID: 35215801
Doi: 10.3390/v14020207
Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome
Authors: Juan Manuel Orozco Rodriguez, Ewa Krupinska, Hanna Wacklin-Knecht, Wolfgang Knecht
Journal: Nucleosides Nucleotides Nucleic Acids
PubMed ID: 35094635
Doi: 10.1080/15257770.2021.2023749
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Lewis fucose is a key moiety for the recognition of histo-blood group antigens by GI9 norovirus, as revealed by structural analysis
Authors: Tomomi Kimura-Someya, Miyuki Kato-Murayama, Kazushige Katsura, Naoki Sakai, Kazutaka Murayama, Kazuharu Hanada, Mikako Shirouzu, Yuichi Someya
Journal: FEBS Open Bio
PubMed ID: 35038379
Doi: 10.1002/2211-5463.13370
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