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Structural characterization of the ANTAR antiterminator domain bound to RNA

Authors: James L Walshe, Rezwan Siddiquee, Karishma Patel, Sandro F Ataide

Journal: Nucleic Acids Res

PubMed ID: 35150565

Doi: 10.1093/nar/gkac074

Products & Services: Gene Synthesis

Neoantigens as potential vaccines in hepatocellular carcinoma

Authors: David Repáraz, Marta Ruiz, Diana Llopiz, Leyre Silva, Enric Vercher, Belén Aparicio, Josune Egea, Ibon Tamayo-Uria, Sandra Hervás-Stubbs, Jorge García-Balduz, Carla Castro, Mercedes Iñarrairaegui, Maria Tagliamonte, Angela Mauriello, Beatrice Cavalluzzo, Luigi Buonaguro, Charlotte Rohrer, Kathrin Heim, Catrin Tauber, Maike Hofmann, Robert Thimme, Bruno Sangro, Pablo Sarobe

Journal: J Immunother Cancer

PubMed ID: 35193931

Doi: 10.1136/jitc-2021-003978

Products & Services: Gene Synthesis

Hydroxychloroquine for prophylaxis of COVID-19 in health workers: A randomized clinical trial

Authors: Jorge Rojas-Serrano, Angelica Margarita Portillo-Vásquez, Ireri Thirion-Romero, Joel Vázquez-Pérez, Fidencio Mejía-Nepomuceno, Alejandra Ramírez-Venegas, Karla Midori Pérez-Kawabe, Rogelio Pérez-Padilla

Journal: PLoS ONE

PubMed ID: 35139097

Doi: 10.1371/journal.pone.0261980

Products & Services: Catalog Antibody

Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry

Authors: Bertrand Simon, Hua Jane Lou, Clotilde Huet-Calderwood, Guangda Shi, Titus J Boggon, Benjamin E Turk, David A Calderwood

Journal: Nat Commun

PubMed ID: 35136069

Doi: 10.1038/s41467-022-28427-0

Products & Services: Proteins, Expression, Isolation and Analysis

Increased Fibrosis in a Mouse Model of Anti-Laminin 332 Mucous Membrane Pemphigoid Remains Unaltered by Inhibition of Aldehyde Dehydrogenase

Authors: Sabrina Patzelt, Manuela Pigors, Heiko Steenbock, Leonard Diel, Katharina Boch, Lenche Chakievska, Sven Künzel, Hauke Busch, Anke Fähnrich, Jürgen Brinckmann, Enno Schmidt

Journal: Front Immunol

PubMed ID: 35197965

Doi: 10.3389/fimmu.2021.812627

Products & Services: Proteins, Expression, Isolation and Analysis

A novel peptide-based electrochemical biosensor for breast cancer characterization over a poly 3-(3-aminophenyl) propionic acid matrix

Authors: Rafael da Fonseca Alves, Isabella Castro Martins, Diego Leoni Franco, Adriane das Graças Silva, Paula de Souza Santos, Luiz Ricardo Goulart, Yara Cristina de Paiva Maia, Alinne Tatiane Faria Silva, Thaise Gonçalves Araújo, Maria Del Pilar Taboada Sotomayor

Journal: Biosens Bioelectron

PubMed ID: 35217253

Doi: 10.1016/j.bios.2022.114081

Products & Services: DNA Sequencing

Finger stick blood test to assess postvaccination SARS-CoV-2 neutralizing antibody response against variants

Authors: Sing Mei Lim, Hoi Lok Cheng, Huan Jia, Patthara Kongsuphol, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Shuvan Prashant Turaga, Sascha P Heussler, Jyoti Somani, Sharmila Sengupta, Dousabel M Y Tay, Megan E McBee, Barnaby E Young, Paul A MacAry, Hadley D Sikes, Peter R Preiser

Journal: Bioeng Transl Med

PubMed ID: 35600666

Doi: 10.1002/btm2.10293

Regulation of integrin α5β1 conformational states and intrinsic affinities by metal ions and the ADMIDAS

Authors: Jordan M Anderson, Jing Li, Timothy A Springer

Journal: Mol Biol Cell

PubMed ID: 35108026

Doi: 10.1091/mbc.E21-11-0536

Products & Services: Catalog Antibody

The receptor CgIL-17R1 expressed in granulocytes mediates the CgIL-17 induced haemocytes proliferation in Crassostrea gigas

Authors: Wanqing Cao, Weilin Wang, Siqi Fan, Jialuo Li, Qing Li, Shasha Wu, Lingling Wang, Linsheng Song

Journal: Dev Comp Immunol

PubMed ID: 35183562

Doi: 10.1016/j.dci.2022.104376

Products & Services: Proteins, Expression, Isolation and Analysis

Genome-wide identification and functional characterization of gene family reveal their involvement in response to drought stress in

Authors: Guangzhen Shi, Xinxia Zhu

Journal: PeerJ

PubMed ID: 35186477

Doi: 10.7717/peerj.12883

Products & Services: Protein Tools

Challenges of expressing recombinant human tissue factor as a secreted protein in

Authors: Mohammad Jalili-Nik, Mohammad Soukhtanloo, Majid Mojarrad, Mohammad Hadi Sadeghian, Baratali Mashkani

Journal: Prep Biochem Biotechnol

PubMed ID: 35133942

Doi: 10.1080/10826068.2021.2023823

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Trans-seeding of Alzheimer-related tau protein by a yeast prion

Authors: Martin Flach, Cedric Leu, Alfonso Martinisi, Zhiva Skachokova, Stephan Frank, Markus Tolnay, Henning Stahlberg, David T Winkler

Journal: Alzheimers Dement

PubMed ID: 35142027

Doi: 10.1002/alz.12581

Products & Services: Mutant Libraries

Development of a Nanoparticle Multiepitope DNA Vaccine against Virulent Infectious Bronchitis Virus Challenge

Authors: Yifeng Qin, Qingyuan Teng, Delan Feng, Yu Pei, Ye Zhao, Guozhong Zhang

Journal: J Immunol

PubMed ID: 35217582

Doi: 10.4049/jimmunol.2100909

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The protective effects of Mirtazapine against lipopolysaccharide (LPS)-induced brain vascular hyperpermeability

Authors: Yuehong Pu, Lei Zhao, Yao Xi, Yichun Xia, Yiming Qian

Journal: Bioengineered

PubMed ID: 35081868

Doi: 10.1080/21655979.2021.2024962

Products & Services: ORF cDNA Clones/MolecularCloud

Trans-seeding of Alzheimer-related tau protein by a yeast prion

Authors: Martin Flach, Cedric Leu, Alfonso Martinisi, Zhiva Skachokova, Stephan Frank, Markus Tolnay, Henning Stahlberg, David T Winkler

Journal: Alzheimers Dement

PubMed ID: 35142027

Doi: 10.1002/alz.12581

Products & Services: Mutant Libraries

Higher SARS-CoV-2 Spike Binding Antibody Levels and Neutralization Capacity 6 Months after Heterologous Vaccination with AZD1222 and BNT162b2

Authors: Brigitte Müller-Hilke, Franz Mai, Michael Müller, Johann Volzke, Emil C Reisinger

Journal: Vaccines (Basel)

PubMed ID: 35214780

Doi: 10.3390/vaccines10020322

Products & Services: Catalog Peptides

SARS-CoV-2 neutralizing capacity among blood donors without prior COVID-19 symptomatic history vs blood donors with prior COVID-19 symptomatic history: A comparative study

Authors: Ushasree Ravula, Srinivasa Rao Chunchu, Srujaleswari Mooli, Ravi Naik, Pandu Ranga Rao Sarangapati

Journal: Transfus Clin Biol

PubMed ID: 35167958

Doi: 10.1016/j.tracli.2022.02.004

Preparation and Immune Effect of HEV ORF2 P206@PLGA Nanoparticles

Authors: Yifei Yang, Zhenning Sun, Huopeng Li, Jijing Tian, Mingyong Chen, Tianlong Liu

Journal: Nanomaterials (Basel)

PubMed ID: 35214924

Doi: 10.3390/nano12040595

Products & Services: Plasmid DNA Preparation

Preparation and Immune Effect of HEV ORF2 P206@PLGA Nanoparticles

Authors: Yifei Yang, Zhenning Sun, Huopeng Li, Jijing Tian, Mingyong Chen, Tianlong Liu

Journal: Nanomaterials (Basel)

PubMed ID: 35214924

Doi: 10.3390/nano12040595

Products & Services: Plasmid DNA Preparation

The interplay of viral loads, clinical presentation, and serological responses in SARS-CoV-2 - Results from a prospective cohort of outpatient COVID-19 cases

Authors: Kerstin Puchinger, Noemi Castelletti, Raquel Rubio-Acero, Christof Geldmacher, Tabea M Eser, Flora Deák, Ivana Paunovic, Abhishek Bakuli, Elmar Saathoff, Alexander von Meyer, Alisa Markgraf, Philine Falk, Jakob Reich, Friedrich Riess, Philipp Girl, Katharina Müller, Katja Radon, Jessica Michelle Guggenbuehl Noller, Roman Wölfel, Michael Hoelscher, Inge Kroidl, Andreas Wieser, Laura Olbrich

Journal: Virology

PubMed ID: 35245784

Doi: 10.1016/j.virol.2022.02.002

Strikingly Different Roles of SARS-CoV-2 Fusion Peptides Uncovered by Neutron Scattering

Authors: Andreas Santamaria, Krishna C Batchu, Olga Matsarskaia, Sylvain F Prévost, Daniela Russo, Francesca Natali, Tilo Seydel, Ingo Hoffmann, Valérie Laux, Michael Haertlein, Tamim A Darwish, Robert A Russell, Giacomo Corucci, Giovanna Fragneto, Armando Maestro, Nathan R Zaccai

Journal: J Am Chem Soc

PubMed ID: 35157798

Doi: 10.1021/jacs.1c09856

Products & Services: Peptide Synthesis

Design of Synthetic Mammalian Promoters Using Highly Palindromic Subsequences

Authors: Polina Govorkova, Chee Ka Candice Lam, Kevin Truong

Journal: ACS Synth Biol

PubMed ID: 35225601

Doi: 10.1021/acssynbio.1c00600

Products & Services: PCR Cloning and Subcloning

Discovery of Small-Molecule VapC1 Nuclease Inhibitors by Virtual Screening and Scaffold Hopping from an Atomic Structure Revealing Protein-Protein Interactions with a Native VapB1 Inhibitor

Authors: Hongmao Sun, Nathan P Coussens, Carina Danchik, Leah M Wachsmuth, Mark J Henderson, Samarjit Patnaik, Matthew D Hall, Ashley L Molinaro, Dayle A Daines, Min Shen

Journal: J Chem Inf Model

PubMed ID: 35103473

Doi: 10.1021/acs.jcim.1c01188

Products & Services: Recombinant Antibody Expression

Preparative capillary electrophoresis (CE) fractionation of protein digests improves protein and peptide identification in bottom-up proteomics

Authors: Simon D Weaver, Naviya Schuster-Little, Rebecca J Whelan

Journal: Anal Methods

PubMed ID: 35175250

Doi: 10.1039/d1ay02145a

Products & Services: Catalog Peptides

Genome-wide identification and characterization of AINTEGUMENTA-LIKE (AIL) family genes in apple (Malus domestica Borkh)

Authors: Xiaolei Han, Kai Liu, Gaopeng Yuan, Shanshan He, Peihua Cong, Caixia Zhang

Journal: Genomics

PubMed ID: 35151838

Doi: 10.1016/j.ygeno.2022.110313

Products & Services: Protein Tools

Discovery and Mechanism of Small Molecule Inhibitors Selective for the Chromatin-Binding Domains of Oncogenic UHRF1

Authors: Wallace H Liu, Robert E Miner, Brittany N Albaugh, Gene E Ananiev, Scott A Wildman, John M Denu

Journal: Biochemistry

PubMed ID: 35143176

Doi: 10.1021/acs.biochem.1c00698

Products & Services: Catalog Peptides

NR3C2 suppresses the proliferation, migration, invasion and angiogenesis of colon cancer cells by inhibiting the AKT/ERK signaling pathway

Authors: Jia Li, Zhao Xu

Journal: Mol Med Rep

PubMed ID: 35191517

Doi: 10.3892/mmr.2022.12649

Products & Services: Custom DNA/RNA Oligos

Ecology and Diversity of Culturable Fungal Species Associated with Soybean Seedling Diseases in the Midwestern United States

Authors: Mirian F Pimentel, Ali Y Srour, Amanda J Warner, Jason P Bond, Carl A Bradley, John Rupe, Martin I Chilvers, J Alejandro Rojas, Janette L Jacobs, Christopher R Little, Alison E Robertson, Loren J Giesler, Dean Malvick, Kiersten Wise, Albert Tenuta, Ahmad M Fakhoury

Journal: J Appl Microbiol

PubMed ID: 35226387

Doi: 10.1111/jam.15507

Products & Services: PCR and Cloning

High-throughput split-protein profiling by combining transposon mutagenesis and regulated protein-protein interactions with deep sequencing

Authors: Kai Zhou, Thomas Litfin, Md Solayman, Huijun Zhao, Yaoqi Zhou, Jian Zhan

Journal: Int J Biol Macromol

PubMed ID: 35120933

Doi: 10.1016/j.ijbiomac.2022.01.173

Products & Services: Custom DNA/RNA Oligos

An insect antifreeze protein from Anatolica polita enhances the cryoprotection of Xenopus laevis eggs and embryos

Authors: Predrag Jevtić, K Wade Elliott, Shelby E Watkins, Jonathan A Sreter, Katarina Jovic, Ian B Lehner, Paul W Baures, John G Tsavalas, Daniel L Levy, Krisztina Varga

Journal: J Exp Biol

PubMed ID: 35014670

Doi: 10.1242/jeb.243662

Products & Services: Custom DNA/RNA Oligos

Ultrasensitive Label-Free DNA Detection Based on Solution-Gated Graphene Transistors Functionalized with Carbon Quantum Dots

Authors: Minghua Deng, Jinhua Li, Bichen Xiao, Zhanpeng Ren, Ziqin Li, Haiyang Yu, Jiashen Li, Jianying Wang, Zhaowei Chen, Xianbao Wang

Journal: Anal Chem

PubMed ID: 35147418

Doi: 10.1021/acs.analchem.1c05309

Products & Services: Gene Synthesis

Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine

Authors: Dapeng Li, David R Martinez, Alexandra Schäfer, Haiyan Chen, Maggie Barr, Laura L Sutherland, Esther Lee, Robert Parks, Dieter Mielke, Whitney Edwards, Amanda Newman, Kevin W Bock, Mahnaz Minai, Bianca M Nagata, Matthew Gagne, Daniel Douek, C Todd DeMarco, Thomas N Denny, Thomas H Oguin, Alecia Brown, Wes Rountree, Yunfei Wang, Katayoun Mansouri, Robert J Edwards, Guido Ferrari, Gregory D Sempowski, Amanda Eaton, Juanjie Tang, Derek W Cain, Sampa Santra, Norbert Pardi, Drew Weissman, Mark Tomai, Christopher Fox, Ian N Moore, Hanne Andersen, Mark G Lewis, Hana Golding, Surender Khurana, Robert Seder, Ralph S Baric, David C Montefiori, Kevin O Saunders, Barton F Haynes

Journal: biorxiv

PubMed ID: 35118474

Doi: 10.1101/2022.01.26.477915

Products & Services: Plasmid DNA Preparation

Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine

Journal: biorxiv

PubMed ID: 35118474

Doi: 10.1101/2022.01.26.477915

Products & Services: Plasmid DNA Preparation

E-cigarette and food flavoring diacetyl alters airway cell morphology, inflammatory and antiviral response, and susceptibility to SARS-CoV-2

Authors: Stephanie N Langel, Francine L Kelly, David M Brass, Andrew E Nagler, Dylan Carmack, Joshua J Tu, Tatianna Travieso, Ria Goswami, Sallie R Permar, Maria Blasi, Scott M Palmer

Journal: Cell Death Discov

PubMed ID: 35169120

Doi: 10.1038/s41420-022-00855-3

Products & Services: Plasmid DNA Preparation

Supramolecular assembly of chloroplast NADH dehydrogenase-like complex with photosystem I from Arabidopsis thaliana

Authors: Xiaodong Su, Duanfang Cao, Xiaowei Pan, Lifang Shi, Zhenfeng Liu, Luca Dall'Osto, Roberto Bassi, Xinzheng Zhang, Mei Li

Journal: Mol Plant

PubMed ID: 35123031

Doi: 10.1016/j.molp.2022.01.020

Products & Services: Gene Synthesis

Structure−Activity Relationship Study of Subtype-Selective Positive Modulators of KCa2 Channels

Authors: Naglaa Salem El-Sayed, Young-Woo Nam, Polina A Egorova, Hai Minh Nguyen, Razan Orfali, Mohammad Asikur Rahman, Grace Yang, Heike Wulff, Ilya Bezprozvanny, Keykavous Parang, Miao Zhang

Journal: J Med Chem

PubMed ID: 34962403

Doi: doi/10.1021/acs.jmedchem.1c01473.

Products & Services: PCR Cloning and Subcloning

A Klotho-derived peptide protects against kidney fibrosis by targeting TGF-β signaling

Authors: Qian Yuan, Qian Ren, Li Li , Huishi Tan, Meizhi Lu, Yuan Tian, Lu Huang, Boxin Zhao, Haiyan Fu, Fan Fan Hou, Lili Zhou, Youhua Liu

Journal: Nat Commun

PubMed ID: 35064106

Doi: 10.1038/s41467-022-28096-z

Products & Services: Peptide Synthesis

A Novel Peptide Derived from Induces Apoptosis in Colorectal Cancer Cells through Mitochondria and the p38 MAPK Pathway

Authors: Chunlei Li, Sirui Zhang, Jianhua Zhu, Weijuan Huang, Yuanyuan Luo, Hui Shi, Dongbo Yu, Liguo Chen, Liyan Song, Rongmin Yu

Journal: Mar Drugs

PubMed ID: 35200639

Doi: 10.3390/md20020110

Products & Services: GenParts™ DNA Fragments

Channelopathy-causing mutations in the SA/SB and HA/HB helices of K23 and K31 channels alter their apparent Ca sensitivity

Authors: Razan Orfali, Young-Woo Nam, Hai Minh Nguyen, Mohammad Asikur Rahman, Grace Yang, Meng Cui, Heike Wulff, Miao Zhang

Journal: Cell Calcium

PubMed ID: 35030515

Doi: 10.1016/j.ceca.2022.102538

Products & Services: Mutagenesis Services

Synthetic nanobody-functionalized nanoparticles for accelerated development of rapid, accessible detection of viral antigens

Authors: Xiahui Chen, Shoukai Kang, Md Ashif Ikbal, Zhi Zhao, Yuxin Pan, Jiawei Zuo, Liangcai Gu, Chao Wang

Journal: Biosens Bioelectron

PubMed ID: 35051851

Doi: 10.1016/j.bios.2022.113971

Products & Services: Proteins, Expression, Isolation and Analysis

Mapping Critical Residues in ATG11's Coiled-Coil 2 Domain that Block Multiple Interactions and Disrupt Selective Autophagy

Authors: Mitchell D Meyer, Jasmine Winzeler, Sophia M Taylor, Alex Kilgore, Kimberly Edicha, Chase Chitwood, Zachary Spearin, S K Nadia Rahman Silvia, Ronith Chakraborty, Jesse E Smith, Bridget Kennedy, Carson Zois, Hayley Cawthon, Mukiri Gilruth, Steven K Backues

Journal: Front Cell Dev Biol

PubMed ID: 35118068

Doi: 10.3389/fcell.2021.775364

Products & Services: Mutagenesis Services

Cadherin switches during epithelial-mesenchymal transition: CDH4/RCAD downregulation reduces bladder cancer progression

Authors: Cláudia Martins-Lima, Vera Miranda-Gonçalves, João Lobo, Vera Constâncio, Pedro Leite-Silva, Catarina Guimarães-Teixeira, Sara Monteiro-Reis, José Pedro Sequeira, Mariana Cantante, Céline S Gonçalves, Bruno M Costa, Rui Henrique, Carmen Jerónimo

Journal: Cell Oncol (Dordr)

PubMed ID: 35064910

Doi: 10.1007/s13402-021-00657-2

Products & Services: Plasmid DNA Preparation

Novel TRPV1 Modulators with Reduced Pungency Induce Analgesic Effects in Mice

Authors: Anny Treat, Vianie Henri, Junke Liu, Joyce Shen, Mauricio Gil-Silva, Alejandro Morales, Avaneesh Rade, Kevin Joseph Tidgewell, Benedict Kolber, Young Shen

Journal: ACS Omega

PubMed ID: 35097287

Doi: 10.1021/acsomega.1c05727

Products & Services: Plasmid DNA Preparation

Peroxisomal ATP Uptake Is Provided by Two Adenine Nucleotide Transporters and the ABCD Transporters

Authors: Carlo W T van Roermund, Lodewijk IJlst, Nicole Linka, Ronald J A Wanders, Hans R Waterham

Journal: Front Cell Dev Biol

PubMed ID: 35127709

Doi: 10.3389/fcell.2021.788921

Products & Services: ORF cDNA Clones/MolecularCloud

An Enzymatic Biosensor for the Detection of D-2-Hydroxyglutaric Acid in Serum and Urine

Authors: Bo Wu, Zehua Li, Zepeng Kang, Chunling Ma, Haiyan Song, Fuping Lu, Zhiguang Zhu

Journal: Biosensors (Basel)

PubMed ID: 35200327

Doi: 10.3390/bios12020066

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CD8 T-Cell Epitope Variations Suggest a Potential Antigen HLA-A2 Binding Deficiency for Spike Protein of SARS-CoV-2

Authors: Congling Qiu, Chanchan Xiao, Zhigang Wang, Guodong Zhu, Lipeng Mao, Xiongfei Chen, Lijuan Gao, Jieping Deng, Jun Su, Huanxing Su, Evandro Fei Fang, Zhang-Jin Zhang, Jikai Zhang, Caojun Xie, Jun Yuan, Oscar Junhong Luo, Li An Huang, Pengcheng Wang, Guobing Chen

Journal: Front Immunol

PubMed ID: 35116022

Doi: 10.3389/fimmu.2021.764949

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Tissue-level alveolar epithelium model for recapitulating SARS-CoV-2 infection and cellular plasticity

Authors: Jia-Wei Yang, Yu-Rou Lin, Ying-Ling Chu, Johnson H Y Chung, Huai-En Lu, Guan-Yu Chen

Journal: Commun Biol

PubMed ID: 35046486

Doi: 10.1038/s42003-022-03026-3

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Development and Evaluation of a Molecular Hepatitis A Virus Assay for Serum and Stool Specimens

Authors: Robert A Kozak, Candace Rutherford, Melissa Richard-Greenblatt, N Y Elizabeth Chau, Ana Cabrera, Mia Biondi, Jamie Borlang, Jaqueline Day, Carla Osiowy, Sumathi Ramachandran, Nancy Mayer, Laurel Glaser, Marek Smieja

Journal: Viruses

PubMed ID: 35062362

Doi: 10.3390/v14010159

Products & Services: Plasmid DNA Preparation

Differential T cell immune responses to deamidated adeno-associated virus vector

Authors: So Jin Bing, Sune Justesen, Wells W Wu, Abdul Mohin Sajib, Stephanee Warrington, Alan Baer, Stephan Thorgrimsen, Rong-Fong Shen, Ronit Mazor

Journal: Mol Ther Methods Clin Dev

PubMed ID: 35211638

Doi: 10.1016/j.omtm.2022.01.005

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Characterization of a Novel Chimeric p67 Antigen Which Incorporates into Virus-like Particles and Is Highly Immunogenic in Mice

Authors: Leah Whittle, Ros Chapman, Michiel van Diepen, Edward P Rybicki, Anna-Lise Williamson

Journal: Vaccines (Basel)

PubMed ID: 35214669

Doi: 10.3390/vaccines10020210

Products & Services: Codon Optimization

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