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Functionally Antagonistic Transcription Factors IRF1 and IRF2 Regulate the Transcription of the Dopamine Receptor D2 Gene Associated with Aggressive Behavior of Weaned Pigs

Authors: Jing Zhao, Siyuan Gao, Yanli Guo, Qinglei Xu, Mingzheng Liu, Chunlei Zhang, Meng Cheng, Xianle Zhao, Allan P Schinckel, Bo Zhou

Journal: Biology (Basel)

PubMed ID: 35053133

Doi: 10.3390/biology11010135

Products & Services: Proteins, Expression, Isolation and Analysis

Azole-Resistant Alleles of in Candida glabrata Trigger Activation of the Pdr1 and Upc2A Transcription Factors

Authors: Bao Gia Vu, W Scott Moye-Rowley

Journal: Antimicrob Agents Chemother

PubMed ID: 35007132

Doi: 10.1128/AAC.02098-21

Products & Services: Polyclonal Antibody Services

Three-repeat and four-repeat tau isoforms form different oligomers

Authors: Hedieh Shahpasand-Kroner, Jennifer Portillo, Carter Lantz, Paul M Seidler, Natalie Sarafian, Joseph A Loo, Gal Bitan

Journal: Protein Sci

PubMed ID: 34902187

Doi: 10.1002/pro.4257

Products & Services: Proteins, Expression, Isolation and Analysis

FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape

Authors: Lei Wu, Yanquan Xu, Huakan Zhao, Yu Zhou, Yu Chen, Shuai Yang, Juan Lei, Jiangang Zhang, Jingchun Wang, Yongzhong Wu, Yongsheng Li

Journal: Theranostics

PubMed ID: 34976216

Doi: 10.7150/thno.66575

Products & Services: Stable Cell Lines

Modulation of the Conformational Space of SARS-CoV-2 RNA Quadruplex RG-1 by Cellular Components and the Amyloidogenic Peptides α-Synuclein and hIAPP

Authors: Sanjib K Mukherjee, Jim-Marcel Knop, Roland Winter

Journal: Chemistry

PubMed ID: 34882862

Doi: 10.1002/chem.202104182

Products & Services: Mammalian Expression

A model for DHX15 mediated disassembly of A-complex spliceosomes

Authors: Hannah M Maul-Newby, Angela N Amorello, Turvi Sharma, John H Kim, Matthew S Modena, Beth E Prichard, Melissa S Jurica

Journal: RNA

PubMed ID: 35046126

Doi: 10.1261/rna.078977.121

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Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts

Authors: Rhia Kundu, Janakan Sam Narean, Lulu Wang, Joseph Fenn, Timesh Pillay, Nieves Derqui Fernandez, Emily Conibear, Aleksandra Koycheva, Megan Davies, Mica Tolosa-Wright, Seran Hakki, Robert Varro, Eimear McDermott, Sarah Hammett, Jessica Cutajar, Ryan S Thwaites, Eleanor Parker, Carolina Rosadas, Myra McClure, Richard Tedder, Graham P Taylor, Jake Dunning, Ajit Lalvani

Journal: Nat Commun

PubMed ID: 35013199

Doi: 10.1038/s41467-021-27674-x

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Recombinant porphobilinogen deaminase targeted to the liver corrects enzymopenia in a mouse model of acute intermittent porphyria

Authors: Karol M Córdoba, Irantzu Serrano-Mendioroz, Daniel Jericó, María Merino, Lei Jiang, Ana Sampedro, Manuel Alegre, Fernando Corrales, María J Garrido, Paolo G V Martini, José Luis Lanciego, Jesús Prieto, Pedro Berraondo, Antonio Fontanellas

Journal: Sci Transl Med

PubMed ID: 35020410

Doi: 10.1126/scitranslmed.abc0700

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Physicochemical Characterization and In Vitro Digestibility Study of an In Silico Designed Recombinant Protein Enriched with Large Neutral Amino Acids and Lacking Phenylalanine for Phenylketonuria

Authors: Prakruthi Appaiah, L Sunil, Asha Martin, Prasanna Vasu

Journal: Protein J

PubMed ID: 35064867

Doi: 10.1007/s10930-021-10039-0

Products & Services: Molecular Biology Tools

Comparison of Wild Type DNA Sequence of Spike Protein from SARS-CoV-2 with Optimized Sequence on The Induction of Protective Responses Against SARS-Cov-2 Challenge in Mouse Model

Authors: Sheng Jiang, Shuting Wu, Gan Zhao, Yue He, Linlin Bao, Jiangning Liu, Chuan Qin, Jiawang Hou, Yuan Ding, Alex Cheng, Brian Jiang, John Wu, Jian Yan, Laurent Humeau, Ami Patella, David B Weiner, Kate Broderick, Bin Wang

Journal: Hum Vaccin Immunother

PubMed ID: 35061975

Doi: 10.1080/21645515.2021.2016201

Products & Services: Molecular Biology Tools

Enzymatic synthesis of cellulose in space: gravity is a crucial factor for building cellulose II gel structure

Authors: Tomohiro Kuga, Naoki Sunagawa, Kiyohiko Igarashi

Journal: Cellulose (Lond)

PubMed ID: 35125685

Doi: 10.1007/s10570-021-04399-0

Products & Services: Bacterial Expression

Structural insight into the molecular mechanism of cilofexor binding to the farnesoid X receptor

Authors: Longying Jiang, Xueke Liu, Hudie Wei, Shuyan Dai, Lingzhi Qu, Xiaojuan Chen, Ming Guo, Yongheng Chen

Journal: Biochem Biophys Res Commun

PubMed ID: 35091108

Doi: 10.1016/j.bbrc.2022.01.069

Products & Services: Peptide Synthesis

Development of Transient Recombinant Expression and Affinity Chromatography Systems for Human Fibrinogen

Authors: Grega Popovic, Nicholas C Kirby, Taylor C Dement, Kristine M Peterson, Caroline E Daub, Heather A Belcher, Martin Guthold, Adam R Offenbacher, Nathan E Hudson

Journal: Int J Mol Sci

PubMed ID: 35162976

Doi: 10.3390/ijms23031054

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Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain

Authors: Enquan Xu, Ravindra Boddu, Hisham A Abdelmotilib, Arpine Sokratian, Kaela Kelly, Zhiyong Liu, Nicole Bryant, Sidhanth Chandra, Samantha M Carlisle, Elliot J Lefkowitz, Ashley S Harms, Etty N Benveniste, Talene A Yacoubian, Laura A Volpicelli-Daley, David G Standaert, Andrew B West

Journal: Mol Neurodegener

PubMed ID: 35012605

Doi: 10.1186/s13024-021-00509-5

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Distribution of serotypes and antibiotic resistance of invasive Pseudomonas aeruginosa in a multi-country collection

Authors: Shamima Nasrin, Nicolas Hegerle, Shaichi Sen, Joseph Nkeze, Sunil Sen, Jasnehta Permala-Booth, Myeongjin Choi, James Sinclair, Milagritos D Tapia, J Kristie Johnson, Samba O Sow, Joshua T Thaden, Vance G Fowler, Karen A Krogfelt, Annelie Brauner, Efthymia Protonotariou, Eirini Christaki, Yuichiro Shindo, Andrea L Kwa, Sadia Shakoor, Ashika Singh-Moodley, Olga Perovic, Jan Jacobs, Octavie Lunguya, Raphael Simon, Alan S Cross, Sharon M Tennant

Journal: BMC Microbiol

PubMed ID: 34991476

Doi: 10.1186/s12866-021-02427-4

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Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection

Authors: Kylie M Konrath, Kevin Liaw, Yuanhan Wu, Xizhou Zhu, Susanne N Walker, Ziyang Xu, Katherine Schultheis, Neethu Chokkalingam, Himanshi Chawla, Jianqiu Du, Nicholas J Tursi, Alan Moore, Jared Adolf-Bryfogle, Mansi Purwar, Emma L Reuschel, Drew Frase, Matthew Sullivan, Benjamin Fry, Igor Maricic, Viviane M Andrade, Christel Iffland, Max Crispin, Kate E Broderick, Laurent M P F Humeau, Ami Patel, Trevor R F Smith, Jesper Pallesen, David B Weiner, Daniel W Kulp

Journal: Cell Rep

PubMed ID: 35090597

Doi: 10.1016/j.celrep.2022.110318

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Identification of a plant endophytic growth-promoting bacteria capable of inhibiting cadmium uptake in rice

Authors: Wei Tian, Le Li, Xiao Xiao, Huili Wu, Yulong Wang, Zhaoyang Hu, Nahmina Begum, Yiping Zou, Laiqing Lou, Ming Chang, Qingsheng Cai

Journal: J Appl Microbiol

PubMed ID: 34216530

Doi: 10.1111/jam.15201

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CDC42 as an epigenetic regulator of ID4 in triple-negative breast tumors

Authors: Daniela Nasif, Sebastian Real, María Roqué, María T Branham

Journal: Breast Cancer

PubMed ID: 35094293

Doi: 10.1007/s12282-022-01334-4

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Nanobody-based anti-CD22-chimeric antigen receptor T cell immunotherapy exhibits improved remission against B-cell acute lymphoblastic leukemia

Authors: Tingting Zhang, Tian Wang, Fengtao You, Zixuan Li, Dan Chen, Kailu Zhang, Shuaiyu Tian, Binjie Sheng, Hai Wu, Licui Jiang, Renyuxue Ma, Gangli An, Huimin Meng, Lin Yang

Journal: Transpl Immunol

PubMed ID: 35051588

Doi: 10.1016/j.trim.2022.101538

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Induction of humoral and cellular immune responses to COVID-19 mRNA and vector vaccines: A prospective cohort study in Bulgarian healthcare workers

Authors: Maria Nikolova, Yana Todorova, Radoslava Emilova, Iva Trifonova, Teodora Gladnishka, Nina Petrova-Yancheva, Tatyana Chervenyakova, Elena Dragusheva, Georgi Popov, Iva Christova

Journal: J Med Virol

PubMed ID: 34997611

Doi: 10.1002/jmv.27572

MPP1 Determines the Mobility of Flotillins and Controls the Confinement of Raft-Associated Molecules

Authors: Agnieszka Biernatowska, Karolina Wójtowicz, Tomasz Trombik, Aleksander F Sikorski, Aleksander Czogalla

Journal: Cells

PubMed ID: 35159121

Doi: 10.3390/cells11030311

Products & Services: Plasmid DNA Preparation

A Novel Potent Carrier for Unconventional Protein Export in

Authors: Magnus Philipp, Kai P Hussnaetter, Michèle Reindl, Kira Müntjes, Michael Feldbrügge, Kerstin Schipper

Journal: Front Cell Dev Biol

PubMed ID: 35083222

Doi: 10.3389/fcell.2021.816335

Products & Services: Proteins, Expression, Isolation and Analysis

Differential effect of deleting members of African swine fever virus multigene families 360 and 505 from the genotype II Georgia 2007/1 isolate on virus replication, virulence and induction of protection

Authors: Anusyah Rathakrishnan, Samuel Connell, Vlad Petrovan, Katy Moffat, Lynnette C Goatley, Tamara Jabbar, Pedro J Sánchez-Cordón, Ana L Reis, Linda K Dixon

Journal: J Virol

PubMed ID: 35044212

Doi: 10.1128/jvi.01899-21

Products & Services: Gene Synthesis

Characterization of a Cleavable Fusion of Human CYP24A1 with Adrenodoxin Reveals the Variable Role of Hydrophobics in Redox Partner Binding

Authors: Natalie Jay, Sean R Duffy, D Fernando Estrada

Journal: Biochemistry

PubMed ID: 34979083

Doi: 10.1021/acs.biochem.1c00770

Products & Services: Mammalian Expression

Blue-light receptor phototropin 1 suppresses immunity to promote Phytophthora infestans infection

Authors: Shaista Naqvi, Qin He, Franziska Trusch, Huishan Qiu, Jasmine Pham, Qingguo Sun, John M Christie, Eleanor M Gilroy, Paul R J Birch

Journal: New Phytol

PubMed ID: 34923631

Doi: 10.1111/nph.17929

Products & Services: Molecular Biology Reagents

Expression, purification and characterization of the suppressor of copper sensitivity (Scs) B membrane protein from Proteus mirabilis

Authors: Russell J Jarrott, Emily J Furlong, Guillaume A Petit, David Drew, Jennifer L Martin, Maria A Halili

Journal: Protein Expr Purif

PubMed ID: 35026386

Doi: 10.1016/j.pep.2022.106047

Products & Services: Codon Optimization

Vps501, a novel vacuolar SNX-BAR protein cooperates with the SEA complex to regulate TORC1 signaling

Authors: Shreya Goyal, Verónica A Segarra, Aaron M Stetcher, Andrew W Truman, Adam M Reitzel, Richard J Chi

Journal: Traffic

PubMed ID: 35098628

Doi: 10.1111/tra.12833

Products & Services: Mutagenesis Services

The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release

Authors: Mila M Paul, Sven Dannhäuser, Lydia Morris, Achmed Mrestani, Martha Hübsch, Jennifer Gehring, Georgios N Hatzopoulos, Martin Pauli, Genevieve M Auger, Grit Bornschein, Nicole Scholz, Dmitrij Ljaschenko, Martin Müller, Markus Sauer, Hartmut Schmidt, Robert J Kittel, Aaron DiAntonio, Ioannis Vakonakis, Manfred Heckmann, Tobias Langenhan

Journal: Brain

PubMed ID: 35022694

Doi: 10.1093/brain/awac011

Products & Services: GenParts™ DNA Fragments

Investigation of putative antimicrobial peptides in Carassius gibel, revealing a practical approach to screening antimicrobials

Authors: Yujun Zhang, Ping Deng, Caijiao Dai, Mengke Wu, Xueqin Liu, Lijuan Li, Xiaoyi Pan, Junfa Yuan

Journal: Fish Shellfish Immunol

PubMed ID: 34990806

Doi: 10.1016/j.fsi.2021.12.050

Products & Services: Recombinant Proteins

Sterility of Sustained-release Buprenorphine

Authors: Shraddha I Cantara, Crystal Gergye, Vanessa K Lee, Michael Huerkamp

Journal: J Am Assoc Lab Anim Sci

PubMed ID: 35082006

Doi: 10.30802/AALAS-JAALAS-21-000105

Products & Services: Gene Synthesis

Core-shell "loading-type" nanomaterials towards: Simultaneous imaging analysis of glutathione and microRNA

Authors: Lin-Lin Lu, Qin Zhang, Yu Gu, Xiang-Ling Li, Jing Jing Xie

Journal: Anal Chim Acta

PubMed ID: 35151402

Doi: 10.1016/j.aca.2022.339551

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Self-assembling ferritin nanoparticles coupled with linear sequences from canine distemper virus haemagglutinin protein elicit robust immune responses

Authors: Bo Wang, Shuang Li, Yongbo Qiao, Yu Fu, Jiaojiao Nie, Shun Jiang, Xin Yao, Yi Pan, Linye Zhao, Congmei Wu, Yuhua Shi, Yuhe Yin, Yaming Shan

Journal: J Nanobiotechnology

PubMed ID: 35012571

Doi: 10.1186/s12951-021-01229-0

Products & Services: Codon Optimization

Crystal structure of the plant feruloyl-coenzyme A monolignol transferase provides insights into the formation of monolignol ferulate conjugates

Authors: Xi Liu, Shuliu Dai, Yu Zhou, Jinyue Liu, Dong Li, Jun Zhang, Yushan Zhu, Qiao Zhao, Yue Feng, Yi Zhang

Journal: Biochem Biophys Res Commun

PubMed ID: 35066379

Doi: 10.1016/j.bbrc.2022.01.037

Products & Services: Proteins, Expression, Isolation and Analysis

Crystal structure of the plant feruloyl-coenzyme A monolignol transferase provides insights into the formation of monolignol ferulate conjugates

Authors: Xi Liu, Shuliu Dai, Yu Zhou, Jinyue Liu, Dong Li, Jun Zhang, Yushan Zhu, Qiao Zhao, Yue Feng, Yi Zhang

Journal: Biochem Biophys Res Commun

PubMed ID: 35066379

Doi: 10.1016/j.bbrc.2022.01.037

Products & Services: Proteins, Expression, Isolation and Analysis

Preparation and characterization of 2-deacetyl-3-O-sulfo-heparosan and its antitumor effects via the fibroblast growth factor receptor pathway

Authors: Zhengqi Zha, Yaoyao Liu, Yinghua Miao, Shiying Liao, Su-Yan Wang, Huiling Tang, Hongping Yin

Journal: Int J Biol Macromol

PubMed ID: 34998873

Doi: 10.1016/j.ijbiomac.2021.12.098

Products & Services: Plasmid DNA Preparation

Nitroreduction of flutamide by NADPH: Cytochrome P450 reductase

Authors: Mohd Faheem Khan, Cormac D Murphy

Journal: Biochem Biophys Rep

PubMed ID: 35097225

Doi: 10.1016/j.bbrep.2022.101209

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Nitroreduction of flutamide by NADPH: Cytochrome P450 reductase

Authors: Mohd Faheem Khan, Cormac D Murphy

Journal: Biochem Biophys Rep

PubMed ID: 35097225

Doi: 10.1016/j.bbrep.2022.101209

Products & Services: Codon Optimization

Bio-nanocapsules for oriented immobilization of DNA aptamers on aptasensors

Authors: Masumi Iijima, Yuki Yamada, Hideo Nakano, Tsutomu Nakayama, Shun'ichi Kuroda

Journal: Analyst

PubMed ID: 35023508

Doi: 10.1039/d1an02278d

Products & Services: GenParts™ DNA Fragments

Longitudinal waning of mRNA vaccine-induced neutralizing antibodies against SARS-CoV-2 detected by an LFIA rapid test

Authors: Qiao Wang, Lili Feng, Haohai Zhang, Juehua Gao, Changchuin Mao, Esther Landesman-Bollag, Gustavo Mostoslavsky, Justin M Lunderberg, Weina Zheng, Shushun Hao, Wenda Gao

Journal: Antib Ther

PubMed ID: 35146332

Doi: 10.1093/abt/tbac004

Products & Services: Proteins, Expression, Isolation and Analysis

Degradation of dimethachlon by a newly isolated bacterium Paenarthrobacter sp strain JH-1 relieves its toxicity against Chlorella ellipsoidea

Authors: Mingliang Zhang, Wankui Jiang, Siyuan Gao, Qian Zhu, Zhijian Ke, Mingli Jiang, Jiguo Qiu, Qing Hong

Journal: Environ Res

PubMed ID: 35031339

Doi: 10.1016/j.envres.2022.112706

Products & Services: Gene Synthesis

Circ_HECTD1 regulates cerebral ischemia injury via mechanisms involving the regulation of let-7c-5p/ROCK1 axis

Authors: Qian Guo, Tingting Guo, Yuanyuan Sun, Tianrong Chen

Journal: Neuroreport

PubMed ID: 34874325

Doi: 10.1097/WNR.0000000000001743

Products & Services: Plasmid DNA Preparation

Involvement of β-cyanoalanine synthase (β-CAS) and sulfurtransferase (ST) in cyanide (CN) assimilation in rice seedlings

Authors: Yu-Xi Feng, Cheng-Zhi Li, Yu-Juan Lin, Xiao-Zhang Yu

Journal: Chemosphere

PubMed ID: 35101430

Doi: 10.1016/j.chemosphere.2022.133789

Products & Services: Protein Tools

Crystal Structure Analysis and IgE Epitope Mapping of Allergic Predominant Region in Filamin C, Scy p 9

Authors: Xin-Rong He, Yang Yang, Shuai Kang, Ye-Xin Chen, Pei-Yi Zheng, Gui-Xia Chen, Xiao-Mei Chen, Min-Jie Cao, Tengchuan Jin, Guang-Ming Liu

Journal: J Agric Food Chem

PubMed ID: 35040643

Doi: 10.1021/acs.jafc.1c07922

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Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells

Authors: Yong Bian, Gang Yin, Gang Wang, Tiantian Liu, Li Liang, Xinyue Yang, Wen Zhang, Decai Tang

Journal: Cell Biol Toxicol

PubMed ID: 35083610

Doi: 10.1007/s10565-021-09681-2

Products & Services: Proteins, Expression, Isolation and Analysis

Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells

Authors: Yong Bian, Gang Yin, Gang Wang, Tiantian Liu, Li Liang, Xinyue Yang, Wen Zhang, Decai Tang

Journal: Cell Biol Toxicol

PubMed ID: 35083610

Doi: 10.1007/s10565-021-09681-2

Products & Services: Proteins, Expression, Isolation and Analysis

Roles of Close Homologues SigB and SigD in Heat and High Light Acclimation of the Cyanobacterium sp PCC 6803

Authors: Otso Turunen, Satu Koskinen, Juha Kurkela, Outi Karhuvaara, Kaisa Hakkila, Taina Tyystjärvi

Journal: Life (Basel)

PubMed ID: 35207450

Doi: 10.3390/life12020162

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Roles of Close Homologues SigB and SigD in Heat and High Light Acclimation of the Cyanobacterium sp PCC 6803

Authors: Otso Turunen, Satu Koskinen, Juha Kurkela, Outi Karhuvaara, Kaisa Hakkila, Taina Tyystjärvi

Journal: Life (Basel)

PubMed ID: 35207450

Doi: 10.3390/life12020162

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Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence

Authors: Stefano Perni, Kurt Beam

Journal: J Gen Physiol

PubMed ID: 35089322

Doi: 10.1085/jgp.202113024

Products & Services: Mammalian Expression

CryoEM analysis of small plant biocatalysts at sub-2 Å resolution

Authors: Nicole Dimos, Carl P O Helmer, Andrea M Chánique, Markus C Wahl, Robert Kourist, Tarek Hilal, Bernhard Loll

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 34981767

Doi: 10.1107/S205979832101216X

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Uncoupling the Excitatory Amino Acid Transporter 2 From Its C-Terminal Interactome Restores Synaptic Glutamate Clearance at Corticostriatal Synapses and Alleviates Mutant Huntingtin-Induced Hypokinesia

Authors: Stefan Hirschberg, Anton Dvorzhak, Seyed M A Rasooli-Nejad, Svilen Angelov, Marieluise Kirchner, Philipp Mertins, Gilla Lättig-Tünnemann, Christoph Harms, Dietmar Schmitz, Rosemarie Grantyn

Journal: Front Cell Neurosci

PubMed ID: 35173582

Doi: 10.3389/fncel.2021.792652

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