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Serum TK1 protein and C-reactive protein correlate to treatment response and predict survival in dogs with hematologic malignancies
Authors: S Saellström, H Sharif, K K Jagarlamudi, H Rönnberg, L Wang, S Eriksson
Journal: Res Vet Sci
PubMed ID: 35245727
Doi: 10.1016/j.rvsc.2022.02.019
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Rapid screening of aptamers for fluorescent targets by integrated digital PCR and flow cytometry
Authors: Xiaona Fang, Wenjing Li, Tian Gao, Qurat Ul Ain Zahra, Zhaofeng Luo, Renjun Pei
Journal: Talanta
PubMed ID: 35180537
Doi: 10.1016/j.talanta.2022.123302
Products & Services: Custom DNA/RNA Oligos   
Immunological characterization of chicken tumor necrosis factor-α (TNF-α) using new sets of monoclonal antibodies specific for poultry TNF-α
Authors: Mingmin Lu, Youngsub Lee, Charles Li, Hyun S Lillehoj
Journal: Dev Comp Immunol
PubMed ID: 35157961
Doi: 10.1016/j.dci.2022.104374
Lanthanide-based β-Tricalcium Phosphate Upconversion Nanoparticles as an Effective Theranostic Nonviral Vectors for Image-Guided Gene Therapy
Authors: Flavia Rodrigues Oliveira Silva, Nelson Batista Lima, Maria Helena Bellini, Luiz Felipe Silva Teixeira, Eric Yiwei Du, Niloufar Jamshidi, Justin Gooding, Adam David Martin, Alexander Macmillan, Christopher Peter Marquis, Pall Thordarson
Journal: Nanotheranostics
PubMed ID: 35223382
Doi: 10.7150/ntno.68789
Products & Services: Mammalian Expression   
Ligation-assisted homologous recombination enables precise genome editing by deploying both MMEJ and HDR
Authors: Zhihan Zhao, Peng Shang, Fanny Sage, Niels Geijsen
Journal: Nucleic Acids Res
PubMed ID: 35212386
Doi: 10.1093/nar/gkac118
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Dioscin promotes autophagy by regulating the AMPK-mTOR pathway in ulcerative colitis
Authors: Han Li, Bo Pang, Bin Nie, Shifang Qu, Kuanxin Zhang, Jinxiu Xu, Ming Yang, Jie Liu, Shasha Li
Journal: Immunopharmacol Immunotoxicol
PubMed ID: 35174751
Doi: 10.1080/08923973.2022.2037632
Dioscin promotes autophagy by regulating the AMPK-mTOR pathway in ulcerative colitis
Authors: Han Li, Bo Pang, Bin Nie, Shifang Qu, Kuanxin Zhang, Jinxiu Xu, Ming Yang, Jie Liu, Shasha Li
Journal: Immunopharmacol Immunotoxicol
PubMed ID: 35174751
Doi: 10.1080/08923973.2022.2037632
Metal Dependence and Functional Diversity of Type I Cas3 Nucleases
Authors: Sining Sun, Zunyu He, Paul Jiang, Rishika Baral, Maria-Eirini Pandelia
Journal: Biochemistry
PubMed ID: 35184547
Doi: 10.1021/acs.biochem.1c00779
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Development of a Test Card Based on Colloidal Gold Immunochromatographic Strips for Rapid Detection of Antibodies against Theileria equi and Babesia caballi
Authors: Guangpu Yang, Kewei Chen, Wei Guo, Zhe Hu, Ting Qi, Diqiu Liu, Yaoxin Wang, Cheng Du, Xiaojun Wang
Journal: Microbiol Spectr
PubMed ID: 35196786
Doi: 10.1128/spectrum.02411-21
Dexmedetomidine inhibits the growth and metastasis of esophageal cancer cells by down-regulation of lncRNA MALAT1
Authors: Wei Zhang, Li Zhang, Xiao-Jun Cai, Dong Li, Feng-Jun Cao, Zhi-Gang Zuo, Ying Song, Xiong-Jie Yu, Shan Liu
Journal: Kaohsiung J Med Sci
PubMed ID: 35199933
Doi: 10.1002/kjm2.12506
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Crystal packing reveals rapamycin-mediated homodimerization of an FK506-binding domain
Authors: Ajit Kumar Singh, Ketul Saharan, Somanath Baral, Sheng Luan, Dileep Vasudevan
Journal: Int J Biol Macromol
PubMed ID: 35218805
Doi: 10.1016/j.ijbiomac.2022.02.107
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Inhibition of the Interaction of TREM-1 and eCIRP Attenuates Inflammation and Improves Survival in Hepatic Ischemia/Reperfusion
Authors: Timothy Borjas, Asha Jacob, HaoTing Yen, Vihas Patel, Gene F Coppa, Monowar Aziz, Ping Wang
Journal: Shock
PubMed ID: 34864782
Doi: 10.1097/SHK.0000000000001894
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Dexmedetomidine inhibits the growth and metastasis of esophageal cancer cells by down-regulation of lncRNA MALAT1
Authors: Wei Zhang, Li Zhang, Xiao-Jun Cai, Dong Li, Feng-Jun Cao, Zhi-Gang Zuo, Ying Song, Xiong-Jie Yu, Shan Liu
Journal: Kaohsiung J Med Sci
PubMed ID: 35199933
Doi: 10.1002/kjm2.12506
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Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening
Authors: Antonella Falconieri, Giovanni Minervini, Federica Quaglia, Geppo Sartori, Silvio C E Tosatto
Journal: Cancers (Basel)
PubMed ID: 35205757
Doi: 10.3390/cancers14041009
Products & Services: Plasmid DNA Preparation   
OmpA may be used as a novel target to enrich and detect Escherichia coli in milk samples
Authors: Yichen Tian, Kaiqing Yang, Yaoqiang Shi, Jinyang Zhang, Qinqin Han, Xueshan Xia, Yuzhu Song
Journal: J Dairy Sci
PubMed ID: 35151480
Doi: 10.3168/jds.2021-20974
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Cytolysin A-mediated protein exportation efficiency and its role in enhancing the fitness of live recombinant Salmonella Typhi vaccine strain
Authors: F-K Loh, S Nathan, S-C Chow, C-M Fang
Journal: Lett Appl Microbiol
PubMed ID: 35138654
Doi: 10.1111/lam.13669
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Enhanced transglycosylation activity of an Endo-F3 mutant by ligand-directed localization
Authors: Xiangman Zou, Zhi Liu, Liya Liu, Wei Shi, Wanzhen Li, Zifen Guo, Feng Tang, Wei Huang
Journal: Org Biomol Chem
PubMed ID: 35166761
Doi: 10.1039/d2ob00030j
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Quantifying Neutralizing Antibodies in Patients with COVID-19 by a Two-Variable Generalized Additive Model
Authors: Kuan-Ting Liu, Yu-Nong Gong, Chung-Guei Huang, Peng-Nien Huang, Kar-Yee Yu, Hou-Chen Lee, Sun-Che Lee, Huan-Jung Chiang, Yu-An Kung, Yueh-Te Lin, Mei-Jen Hsiao, Po-Wei Huang, Sheng-Yu Huang, Hsin-Tai Wu, Chih-Ching Wu, Rei-Lin Kuo, Kuan-Fu Chen, Chuan-Tien Hung, Kasopefoluwa Y Oguntuyo, Christian S Stevens, Shreyas Kowdle, Hsin-Ping Chiu, Benhur Lee, Guang-Wu Chen, Shin-Ru Shih
Journal: mSphere
PubMed ID: 35107336
Doi: 10.1128/msphere.00883-21
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Charge-Modulated Accessibility of Tyrosine Residues for Silk-Elastin Copolymer Cross-Linking
Authors: Constancio Gonzalez-Obeso, Fredrik G Backlund, David L Kaplan
Journal: Biomacromolecules
PubMed ID: 35113522
Doi: 10.1021/acs.biomac.1c01192
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SARS-CoV-2 neutralizing capacity among blood donors without prior COVID-19 symptomatic history vs blood donors with prior COVID-19 symptomatic history: A comparative study
Authors: Ushasree Ravula, Srinivasa Rao Chunchu, Srujaleswari Mooli, Ravi Naik, Pandu Ranga Rao Sarangapati
Journal: Transfus Clin Biol
PubMed ID: 35167958
Doi: 10.1016/j.tracli.2022.02.004
Melanocortin receptor agonists suppress experimental autoimmune uveitis
Authors: Tat Fong Ng, Kaleb Dawit, Andrew W Taylor
Journal: Exp Eye Res
PubMed ID: 35196505
Doi: 10.1016/j.exer.2022.108986
Products & Services: Mammalian Expression   
Impact of the clinically approved Petasites hybridus extract Ze 339 on intestinal mechanisms involved in the handling of histamine
Authors: Lina G Mettler, Karin Brecht, Veronika Butterweck, Henriette E Meyer Zu Schwabedissen
Journal: Biomed Pharmacother
PubMed ID: 35149385
Doi: 10.1016/j.biopha.2022.112698
IL-4 plays an essential role in DnaJ-ΔA146Ply-mediated immunoprotection against Streptococcus pneumoniae in mice
Authors: Yi Hu, Lian Li, Wenchun Xu, Kaifeng Wu, Jiangming Xiao, Yang Peng, Yusi Liu, Yibing Yin, Xuemei Zhang
Journal: Mol Immunol
PubMed ID: 35114487
Doi: 10.1016/j.molimm.2022.01.010
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The interplay of viral loads, clinical presentation, and serological responses in SARS-CoV-2 - Results from a prospective cohort of outpatient COVID-19 cases
Authors: Kerstin Puchinger, Noemi Castelletti, Raquel Rubio-Acero, Christof Geldmacher, Tabea M Eser, Flora Deák, Ivana Paunovic, Abhishek Bakuli, Elmar Saathoff, Alexander von Meyer, Alisa Markgraf, Philine Falk, Jakob Reich, Friedrich Riess, Philipp Girl, Katharina Müller, Katja Radon, Jessica Michelle Guggenbuehl Noller, Roman Wölfel, Michael Hoelscher, Inge Kroidl, Andreas Wieser, Laura Olbrich
Journal: Virology
PubMed ID: 35245784
Doi: 10.1016/j.virol.2022.02.002
Knockdown of long non‑coding RNA DDX11‑AS1 inhibits the proliferation, migration and paclitaxel resistance of breast cancer cells by upregulating microRNA‑497 expression
Authors: Meng Liang, Beibei Zhu, Min Wang, Ju Jin
Journal: Mol Med Rep
PubMed ID: 35169864
Doi: 10.3892/mmr.2022.12639
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Knockdown of long non‑coding RNA DDX11‑AS1 inhibits the proliferation, migration and paclitaxel resistance of breast cancer cells by upregulating microRNA‑497 expression
Authors: Meng Liang, Beibei Zhu, Min Wang, Ju Jin
Journal: Mol Med Rep
PubMed ID: 35169864
Doi: 10.3892/mmr.2022.12639
Products & Services: Gene Synthesis   
Biochemical Screening of Potent Zika Virus Protease Inhibitors
Authors: Camila Coelho, Gloria Gallo, Leon Hardy, Maria Elena Bottazzi, Claudia Campos, Martin Würtele
Journal: ChemMedChem
PubMed ID: 35104396
Doi: 10.1002/cmdc.202100695
Circular dichroism spectroscopic assessment of structural changes upon protein thermal unfolding at contrasting pH: Comparison with molecular dynamics simulations
Authors: Ponciano García-Gutiérrez, Menandro Camarillo-Cadena, Liliana I Vera-Robles, Rafael A Zubillaga, Andrés Hernández-Arana
Journal: Spectrochim Acta A Mol Biomol Spectrosc
PubMed ID: 35245803
Doi: 10.1016/j.saa.2022.121039
Products & Services: Gene Synthesis   
Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines
Authors: Noëmi Johanna Roos, Riccardo Vincenzo Mancuso, Gerda Mawududzi Sanvee, Jamal Bouitbir, Stephan Krähenbühl
Journal: Food Chem Toxicol
PubMed ID: 35182693
Doi: 10.1016/j.fct.2022.112869
Molecular characterization of the serotonergic transporter from the cestode Echinococcus granulosus: pharmacology and potential role in the nervous system
Authors: Federico Camicia, Hugo R Vaca, Ines Guarnaschelli, Uriel Koziol, Ole V Mortensen, Andreia C K Fontana
Journal: Parasitol Res
PubMed ID: 35169884
Doi: 10.1007/s00436-022-07466-y
Products & Services: Mammalian Expression   
Molecular characterization of the serotonergic transporter from the cestode Echinococcus granulosus: pharmacology and potential role in the nervous system
Authors: Federico Camicia, Hugo R Vaca, Ines Guarnaschelli, Uriel Koziol, Ole V Mortensen, Andreia C K Fontana
Journal: Parasitol Res
PubMed ID: 35169884
Doi: 10.1007/s00436-022-07466-y
Products & Services: Mammalian Expression   
Alterations in calmodulin-cardiac ryanodine receptor molecular recognition in congenital arrhythmias
Authors: Giuditta Dal Cortivo , Carlo Giorgio Barracchia , Valerio Marino , Mariapina D'Onofrio , Daniele Dell'Orco
Journal: Cell Mol Life Sci
PubMed ID: 35133504
Doi: 10.1007/s00018-022-04165-w
Products & Services: Plasmid DNA Preparation   
The Structure of the Arabidopsis PEX4-PEX22 Peroxin Complex—Insights Into Ubiquitination at the Peroxisomal Membrane
Authors: Melissa S Traver , Sarah E Bradford , Jose Luis Olmos Jr , Zachary J Wright , Mitchell D Miller , Weijun Xu , George N Phillips Jr , Bonnie Bartel
Journal: Front Cell Dev Biol
PubMed ID: 35300425
Doi: 10.3389/fcell.2022.838923
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A continuous assay set to screen and characterize novel protein N-acetyltransferases unveils rice GNAT2 activity
Authors: Thomas Asensio , Cyril Dian , Jean-Baptiste Boyer , Frédéric Rivière, Thierry Meinnel , Carmela Giglione
Journal: Front Plant Sci
PubMed ID: 35273627
Doi: 10.3389/fpls.2022.832144
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Exploring Noncovalent Protease Inhibitors for the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses
Authors: Brendan T Freitas, Daniil A Ahiadorme, Rahul S Bagul, Ian A Durie, Samir Ghosh, Jarvis Hill, Naomi E Kramer, Jackelyn Murray, Brady M O'Boyle, Emmanuel Onobun, Michael G Pirrone, Justin D Shepard, Suzanne Enos, Yagya P Subedi, Kapil Upadhyaya, Ralph A Tripp, Brian S Cummings, David Crich, Scott D Pegan
Journal: ACS Infect Dis
PubMed ID: 35199517
Doi: 10.1021/acsinfecdis.1c00631
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Biochemical and Biophysical Characterisation of the Hepatitis E Virus Guanine-7-Methyltransferase
Authors: Preeti Hooda, Mohd Ishtikhar, Shweta Saraswat, Pooja Bhatia, Deepali Mishra, Aditya Trivedi, Rajkumar Kulandaisamy, Soumya Aggarwal, Manoj Munde, Nemat Ali, Abdullah F AlAsmari, Mohd A Rauf, Krishna K Inampudi, Deepak Sehgal
Journal: Molecules
PubMed ID: 35268608
Doi: 10.3390/molecules27051505
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DCHS1, Lix1L, and the Septin Cytoskeleton: Molecular and Developmental Etiology of Mitral Valve Prolapse
Authors: Kelsey S Moore, Reece Moore, Diana B Fulmer, Lilong Guo, Cortney Gensemer, Rebecca Stairley, Janiece Glover, Tyler C Beck, Jordan E Morningstar, Rachel Biggs, Rupak Muhkerjee, Alexander Awgulewitsch, Russell A Norris
Journal: J Cardiovasc Dev Dis
PubMed ID: 35200715
Doi: 10.3390/jcdd9020062
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Comprehensive mapping of SARS-CoV-2 peptide epitopes for development of a highly sensitive serological test for total and neutralizing antibodies
Authors: Garima Kumar, Sarah Sterrett, Lucinda Hall, Edlue Tabengwa, Kazuhito Honjo, Michael Larimer, Randall S Davis, Paul A Goepfert, Benjamin M Larimer
Journal: Protein Eng Des Sel
PubMed ID: 35174857
Doi: 10.1093/protein/gzab033
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Systematic profiling of antigen bias in humoral response against SARS-CoV-2
Authors: Nana Wei, Qiujing Wang, Zhibing Lin, Liyun Xu, Zheen Zhang, Yan Wang, Zhejuan Yang, Lue Li, Tingxiao Zhao, Lu Wang, Haifei Lou, Mingfang Han, Mingliang Ma, Yaosheng Jiang, Jinmiao Lu, Shilan Zhu, Li Cui, Shibo Li
Journal: Virus Res
PubMed ID: 35176329
Doi: 10.1016/j.virusres.2022.198711
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Non-Invasive Monitoring for Rejection in Kidney Transplant Recipients After SARS-CoV-2 mRNA Vaccination
Authors: Ayman Al Jurdi, Rodrigo B Gassen, Thiago J Borges, Zhabiz Solhjou, Frank E Hullekes, Isadora T Lape, Orhan Efe, Areej Alghamdi, Poojan Patel, John Y Choi, Mostafa T Mohammed, Brigid Bohan, Vikram Pattanayak, Ivy Rosales, Paolo Cravedi, Camille N Kotton, Jamil R Azzi, Leonardo V Riella
Journal: Front Immunol
PubMed ID: 35281011
Doi: 10.3389/fimmu.2022.838985
miR-145-5p inhibits the proliferation of glioma stem cells by targeting translationally controlled tumor protein
Authors: Qiujian Zhang, Zhe Cheng, Lei Shi, Gengsheng Mao
Journal: J Cancer
PubMed ID: 35371310
Doi: 10.7150/jca.65543
A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination
Authors: Sarah F Andrews, Julie E Raab, Jason Gorman, Rebecca A Gillespie, Crystal S F Cheung, Reda Rawi, Lauren Y Cominsky, Jeffrey C Boyington, Adrian Creanga, Chen-Hsiang Shen, Darcy R Harris, Adam S Olia, Alexandra F Nazzari, Tongqing Zhou, Katherine V Houser, Grace L Chen, John R Mascola, Barney S Graham, Masaru Kanekiyo, Julie E Ledgerwood, Peter D Kwong, Adrian B McDermott
Journal: Nat Med
PubMed ID: 35115707
Doi: 10.1038/s41591-021-01636-8
Products & Services: Recombinant Antibody Expression   
Enrofloxacin Promotes Plasmid-Mediated Conjugation Transfer of Fluoroquinolone-Resistance Gene
Authors: Yue Zhao, Zhengzheng Cao, Luqing Cui, Tianyu Hu, Kaixuan Guo, Fan Zhang, Xiangru Wang, Zhong Peng, Quan Liu, Menghong Dai
Journal: Front Microbiol
PubMed ID: 35250901
Doi: 10.3389/fmicb.2021.773664
A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protects Pigs against PCV2b Challenge and Induces Serum Neutralizing Antibody Response against CSFV
Authors: Selvaraj Pavulraj, Katrin Pannhorst, Rhett W Stout, Daniel B Paulsen, Mariano Carossino, Denise Meyer, Paul Becher, Shafiqul I Chowdhury
Journal: Vaccines (Basel)
PubMed ID: 35214763
Doi: 10.3390/vaccines10020305
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Selective Detection of Serogroup 1 and 5 with a Digital Photocorrosion Biosensor Using Antimicrobial Peptide-Antibody Sandwich Strategy
Authors: M Amirul Islam, Walid M Hassen, Ishika Ishika, Azam F Tayabali, Jan J Dubowski
Journal: Biosensors (Basel)
PubMed ID: 35200365
Doi: 10.3390/bios12020105
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Molecular basis of receptor binding and antibody neutralization of Omicron
Authors: Qin Hong, Wenyu Han, Jiawei Li, Shiqi Xu, Yifan Wang, Cong Xu, Zuyang Li, Yanxing Wang, Chao Zhang, Zhong Huang, Yao Cong
Journal: Nature
PubMed ID: 35228716
Doi: 10.1038/s41586-022-04581-9
Products & Services: Mammalian Expression   
Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress
Authors: Mark Stoneley, Robert F Harvey, Thomas E Mulroney, Ryan Mordue, Rebekah Jukes-Jones, Kelvin Cain, Kathryn S Lilley, Ritwick Sawarkar, Anne E Willis
Journal: Mol Cell
PubMed ID: 35180429
Doi: 10.1016/j.molcel.2022.01.019
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Far-Red Light Triggered Production of Bispecific T Cell Engagers (BiTEs) from Engineered Cells for Antitumor Application
Authors: Cuilin Zhang, Yingjun Shi, Lingjie Wu, Chenyi Wang, Naishun Liao, Fei Wang, Bixing Zhao, Yingchao Wang, Xiaolong Liu
Journal: ACS Synth Biol
PubMed ID: 35113526
Doi: 10.1021/acssynbio.1c00523
The small heat shock protein HSPB5 attenuates the severity of lupus nephritis in lupus-prone mice
Authors: Spencer Iner Thomas Berg, Justin Knapp, Marsela Braunstein, Cody Shirriff
Journal: Autoimmunity
PubMed ID: 35137667
Doi: 10.1080/08916934.2022.2027921
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