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Development of a Factor VII Activating Protease (FSAP) generation assay and its application in studying FSAP in venous thrombosis
Authors: Michael Etscheid, Kay-Martin Hanschmann, Per Morten Sandset, Sandip M Kanse
Journal: Thromb Res
PubMed ID: 36265411
Doi: 10.1016/j.thromres.2022.09.027
Products & Services: Gene Synthesis   
Ablation of CD8 T cell recognition of an immunodominant epitope in SARS-CoV-2 Omicron variants BA1, BA2 and BA3
Authors: Srividhya Swaminathan, Katie E Lineburg, Archana Panikkar, Jyothy Raju, Lawton D Murdolo, Christopher Szeto, Pauline Crooks, Laetitia Le Texier, Sweera Rehan, Michael J Dewar-Oldis, Peter J Barnard, George R Ambalathingal, Michelle A Neller, Kirsty R Short, Stephanie Gras, Rajiv Khanna, Corey Smith
Journal: Nat Commun
PubMed ID: 36302758
Doi: 10.1038/s41467-022-34180-1
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The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain
Authors: Lavanya Moparthi, Viktor Sinica, Vamsi K Moparthi, Mohamed Kreir, Thibaut Vignane, Milos R Filipovic, Viktorie Vlachova, Peter M Zygmunt
Journal: Nat Commun
PubMed ID: 36253390
Doi: 10.1038/s41467-022-33876-8
Products & Services: Insect Expression   
N-Acylethanolamine acid amidase (NAAA) exacerbates psoriasis inflammation by enhancing dendritic cell (DCs) maturation
Authors: Yuhang Li, Yitian Li, Sennan Xu, Yue Chen, Pan Zhou, Ting Hu, Hua Li, Ying Liu, Yaping Xu, Jie Ren, Yan Qiu, Canzhong Lu
Journal: Pharmacol Res
PubMed ID: 36244543
Doi: 10.1016/j.phrs.2022.106491
Products & Services: Recombinant Proteins   
Achieving regioselective materials binding using multidomain peptides
Authors: Ruitao Jin, Nermina Brljak, Robert Sangrigoli, Tiffany R Walsh, Marc R Knecht
Journal: Nanoscale
PubMed ID: 36073151
Doi: 10.1039/d2nr03169h
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Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif
Authors: Wenwen Ru, Tomoyuki Koga, Xiaoyang Wang, Qiong Guo, Micah D Gearhart, Shidong Zhao, Mark Murphy, Hiroko Kawakami, Dylan Corcoran, Jiahai Zhang, Zhongliang Zhu, Xuebiao Yao, Yasuhiko Kawakami, Chao Xu
Journal: J Biol Chem
PubMed ID: 36257403
Doi: 10.1016/j.jbc.2022.102607
Products & Services: Mammalian Expression   
Tannin Reduces the Incidence of Polyspermic Penetration in Porcine Oocytes
Authors: Jing-Tao Sun, Jia-Hui Liu, Xi-Qing Jiang, Xin Luo, Jin-Dong Yuan, Qi Zhang, Xin-Yue Qi, Sanghoon Lee, Zhong-Hua Liu, Jun-Xue Jin
Journal: Antioxidants (Basel)
PubMed ID: 36290750
Doi: 10.3390/antiox11102027
Products & Services: Protein and Antibody Isolation   
Immunization with CRT-Induced Protective Immunity against Infection in BALB/c Mice
Authors: Lujuan Chen, Zhe Cheng, Siqi Xian, Bin Zhan, Zhijian Xu, Yan Yan, Jianfang Chen, Yanhai Wang, Limei Zhao
Journal: Trop Med Infect Dis
PubMed ID: 36288020
Doi: 10.3390/tropicalmed7100279
Products & Services: Endotoxin Detection & Removal System   
Genetic variation in gene linked to predisposition of T2DM: A case control study
Authors: Archna Bhargave, Kiran Devi, Imteyaz Ahmad, Anita Yadav, Ranjan Gupta
Journal: J Diabetes Metab Disord
PubMed ID: 36249912
Doi: 10.1007/s40200-022-01131-y
Products & Services: Molecular Biology Tools   
Molecular cloning and characterization of a novel bifunctional cellobiohydrolase/β-xylosidase from a metagenomic library of mangrove soil
Authors: Yi-De Liu, Ge Yuan, Yu-Ting An, Zi-Ran Zhu, Gang Li
Journal: Enzyme Microb Technol
PubMed ID: 36265247
Doi: 10.1016/j.enzmictec.2022.110141
Products & Services: Recombinant Proteins   
Efficacy and Safety of a Brain-Penetrant Biologic TNF-α Inhibitor in Aged APP/PS1 Mice
Authors: Weijun Ou, Yuu Ohno, Joshua Yang, Devaraj V Chandrashekar, Tamara Abdullah, Jiahong Sun, Riley Murphy, Chuli Roules, Nataraj Jagadeesan, David H Cribbs, Rachita K Sumbria
Journal: Pharmaceutics
PubMed ID: 36297637
Doi: 10.3390/pharmaceutics14102200
Products & Services: Protein and Antibody Isolation   
Phytoremediation of isoproturon-contaminated sites by transgenic soybean
Authors: Xiangkun Kong, Na Lv, Songmeng Liu, Hui Xu, Junwei Huang, Xiangting Xie, Qing Tao, Baozhan Wang, Rong Ji, Qun Zhang, Jiandong Jiang
Journal: Plant Biotechnol J
PubMed ID: 36278914
Doi: 10.1111/pbi.13951
Products & Services: Protein and Antibody Isolation   
Microsomal triglyceride transfer protein regulates intracellular lipolysis in adipocytes independent of its lipid transfer activity
Authors: Sujith Rajan, Peter Hofer, Amanda Christiano, Matthew Stevenson, Louis Ragolia, Eugenia Villa-Cuesta, Susan K Fried, Raymond Lau, Collin Braithwaite, Rudolf Zechner, Gary J Schwartz, M Mahmood Hussain
Journal: Metabolism
PubMed ID: 36228741
Doi: 10.1016/j.metabol.2022.155331
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Development of CD163 receptor-based enzyme-linked immunosorbent assay for diagnosis of porcine reproductive and respiratory syndrome virus
Authors: Rajib Deb, Ajay Kumar Yadav, Gyanendra Singh Sengar, Joyshikh Sonowal, D Lalita, Seema Rani Pegu, Indra Singh, Ningthoukhongjam Linda, Pranab Jyoti Das, Satish Kumar, Prasanna Pal, Souvik Paul, Swaraj Rajkhowa, Vivek Kumar Gupta
Journal: 3 Biotech
PubMed ID: 36276438
Doi: 10.1007/s13205-022-03376-z
Products & Services: Gene Synthesis   
LncRNA XIST from the bone marrow mesenchymal stem cell derived exosome promotes osteosarcoma growth and metastasis through miR-655/ACLY signal
Authors: Guanghui Zhu, Yu Xia, Ziyue Zhao, Aoyu Li, Hui Li, Tao Xiao
Journal: Cancer Cell Int
PubMed ID: 36309693
Doi: 10.1186/s12935-022-02746-0
Products & Services: Custom DNA/RNA Oligos   
The PSI Domain of the MET Oncogene Encodes a Functional Disulfide Isomerase Essential for the Maturation of the Receptor Precursor
Authors: Dogus Murat Altintas, Simona Gallo, Cristina Basilico, Marina Cerqua, Alessio Bocedi, Annapia Vitacolonna, Orsola Botti, Elena Casanova, Ilaria Rancati, Chiara Milanese, Sara Notari, Giorgia Gambardella, Giorgio Ricci, Pier Giorgio Mastroberardino, Carla Boccaccio, Tiziana Crepaldi, Paolo Maria Comoglio
Journal: Int J Mol Sci
PubMed ID: 36293286
Doi: 10.3390/ijms232012427
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COX7A2L genetic variants determine cardiorespiratory fitness in mice and human
Authors: Giorgia Benegiamo, Maroun Bou Sleiman, Martin Wohlwend, Sandra Rodríguez-López, Ludger J E Goeminne, Pirkka-Pekka Laurila, Marie Klevjer, Minna K Salonen, Jari Lahti, Pooja Jha, Sara Cogliati, José Antonio Enriquez, Ben M Brumpton, Anja Bye, Johan G Eriksson, Johan Auwerx
Journal: Nat Metab
PubMed ID: 36253618
Doi: 10.1038/s42255-022-00655-0
Products & Services: Mammalian Expression   
Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium
Authors: Léa Conchou, Bastien Doumèche, Frédéric Galisson, Sébastien Violot, Chloé Dugelay, Eric Diesis, Adeline Page, Anne-Lise Bienvenu, Stéphane Picot, Nushin Aghajari, Lionel Ballut
Journal: Commun Biol
PubMed ID: 36316540
Doi: 10.1038/s42003-022-04091-4
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APC/CCdc20-mediated degradation of Clb4 prompts astral microtubule stabilization at anaphase onset
Authors: Federico Zucca, Clara Visintin, Jiaming Li, Steven P Gygi, Rosella Visintin
Journal: J Cell Biol
PubMed ID: 36269172
Doi: 10.1083/jcb.202203089
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EP-Pred: A Machine Learning Tool for Bioprospecting Promiscuous Ester Hydrolases
Authors: Ruite Xiang, Laura Fernandez-Lopez, Ana Robles-Martín, Manuel Ferrer, Victor Guallar
Journal: Biomolecules
PubMed ID: 36291739
Doi: 10.3390/biom12101529
Products & Services: Recombinant Proteins   
Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack
Authors: Shuang Yang, Giorgos Hiotis, Yi Wang, Junjian Chen, Jia-Huai Wang, Mikyung Kim, Ellis L Reinherz, Thomas Walz
Journal: Nat Commun
PubMed ID: 36302771
Doi: 10.1038/s41467-022-34008-y
Products & Services: Protein and Antibody Isolation   
Development of a simple PCR-RFLP technique for detection and differentiation of E histolytica, E dispar and E moshkovskii
Authors: Sanjib K Sardar, Seiki Kobayashi, Koushik Das, Yumiko Saito-Nakano, Shanta Dutta, Tomoyoshi Nozaki, Sandipan Ganguly
Journal: Parasitol Res
PubMed ID: 36308533
Doi: 10.1007/s00436-022-07706-1
Products & Services: Molecular Biology Tools   
Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein
Authors: Xiaodong Luan, Xinming Li, Yufan Li, Gengchen Su, Wanchao Yin, Yi Jiang, Ning Xu, Feng Wang, Wang Cheng, Ye Jin, Leike Zhang, H. Eric Xu, Yi Xue, Shuyang Zhang
Journal: Science Bulletin
Doi: 10.1016/j.scib.2022.10.021
Products & Services: Gene Synthesis   
A humanized 4-1BB-targeting agonistic antibody exerts potent antitumor activity in colorectal cancer without systemic toxicity
Authors: Lian-Sheng Cheng, Yong-Feng Cheng, Wen-Ting Liu, Aolin Shen, Dayan Zhang, Tingjuan Xu, Wu Yin, Min Cheng, Xiaopeng Ma, Fengrong Wang, Qun Zhao, Xiaoli Zeng, Yan Zhang, Guodong Shen
Journal: J Transl Med
PubMed ID: 36076251
Doi: 10.1186/s12967-022-03619-w
Products & Services: Mammalian Expression   
Nuclear Factor Kappa B Promotes Ferritin Heavy Chain Expression in in Response to Nucleopolyhedrovirus Infection
Authors: Linbao Zhu, Yingxue Liu, Ancheng Wang, Xiya Chen, Handan Zhu, Zhihao Huang, Huihua Cao, Shihuo Liu, Jiaping Xu
Journal: Int J Mol Sci
PubMed ID: 36142290
Doi: 10.3390/ijms231810380
Products & Services: Recombinant Antibody Expression   
Tumor-Intrinsic PD-L1 Exerts an Oncogenic Function through the Activation of the Wnt/β-Catenin Pathway in Human Non-Small Cell Lung Cancer
Authors: Yunxia Ma, Rumyana Marinkova, Miljana Nenkov, Lai Jin, Otmar Huber, Jürgen Sonnemann, Natália Peca, Nikolaus Gaßler, Yuan Chen
Journal: Int J Mol Sci
PubMed ID: 36232331
Doi: 10.3390/ijms231911031
Products & Services: Mammalian Expression   
A review post-vaccination SARS-CoV-2 serological test: Method and antibody titer response
Authors: Melania Janisha Devi, Shabarni Gaffar, Yeni Wahyuni Hartati
Journal: Anal Biochem
PubMed ID: 36122603
Doi: 10.1016/j.ab.2022.114902
Products & Services: Recombinant Proteins   
Targeting of palpable B16-F10 melanoma tumors with polyclonal antibodies on white blood cells
Authors: Girja S Shukla, Stephanie C Pero, Linda Mei, Yu-Jing Sun, David N Krag
Journal: J Immunol Methods
PubMed ID: 36174735
Doi: 10.1016/j.jim.2022.113362
Products & Services: Catalog Peptides   
Plant transcripts with long or structured uORFs in NDL2 5' UTR can escape NMD in a reinitiation independent manner
Authors: Miryam A Cymerman, Helen Saul, Ronit Farhi, Karina Vexler, Dror Gottlieb, Irina Berezin, Orit Shaul
Journal: J Exp Bot
PubMed ID: 36169317
Doi: 10.1093/jxb/erac385
Products & Services: Protein and Antibody Isolation   
Fluorescence Spectroscopy of Low-Level Endogenous β-Adrenergic Receptor Expression at the Plasma Membrane of Differentiating Human iPSC-Derived Cardiomyocytes
Authors: Philipp Gmach, Marc Bathe-Peters, Narasimha Telugu, Duncan C Miller, Paolo Annibale
Journal: Int J Mol Sci
PubMed ID: 36142320
Doi: 10.3390/ijms231810405
Products & Services: Plasmid DNA Preparation   
Herpes simplex virus lymphadenitis is associated with tumor reduction in a patient with chronic lymphocytic leukemia
Authors: Andres Chang, Anton M Sholukh, Andreas Wieland, David L Jaye, Mary Carrington, Meei-Li Huang, Hong Xie, Keith R Jerome, Pavitra Roychoudhury, Alexander L Greninger, Jean L Koff, Jonathon B Cohen, David M Koelle, Lawrence Corey, Christopher R Flowers, Rafi Ahmed
Journal: J Clin Invest
PubMed ID: 35862190
Doi: 10.1172/JCI161109
Products & Services: Peptide Synthesis   
Microarray-guided evaluation of the frequency, B-cell origins, and selectivity of human glycan-binding antibodies reveals new insights and novel antibodies
Authors: J Sebastian Temme, Jennifer A Crainic, Laura M Walker, Weizhun Yang, Zibin Tan, Xuefei Huang, Jeffrey C Gildersleeve
Journal: J Biol Chem
PubMed ID: 36087840
Doi: 10.1016/j.jbc.2022.102468
Products & Services: Plasmid DNA Preparation   
Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor
Authors: Xiyuan Zhang, Hannah E Lou, Vishaka Gopalan, Zhihui Liu, Hilda M Jafarah, Haiyan Lei, Paige Jones, Carly M Sayers, Marielle E Yohe, Prashant Chittiboina, Brigitte C Widemann, Carol J Thiele, Michael C Kelly, Sridhar Hannenhalli, Jack F Shern
Journal: Cell Rep
PubMed ID: 36130486
Doi: 10.1016/j.celrep.2022.111363
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Preclinical evaluation of new C-11 labeled benzo-1,4-dioxane PET radiotracers for brain α2C adrenergic receptors
Authors: Santosh Alluri,Seth M. Eisenberg,Laurel A. Grisanti,Miles Tanner,Nora D. Volkow,Sung Won Kim,Kun-Eek Kil
Journal: European Journal of Medicinal Chemistry
Doi: doi.org/10.1016/j.ejmech.2022.114764
Products & Services: ORF cDNA Clones/MolecularCloud   
E2/E3‐independent ubiquitin‐like protein conjugation by Urm1 is directly coupled to cysteine persulfidation
Authors: Keerthiraju E Ravichandran , Lars Kaduhr , Bozena Skupien-Rabian , Ekaterina Shvetsova , Mikołaj Sokołowski , Ros Cisław Krutyhołowa ,Dominika Kwasna , Cindy Brachmann , Sean Lin , Sebastian Guzman Perez , Piotr Wilk , Manuel Kösters , Przemysław Grudnik , Urszula Jankowska , Sebastian A Leidel , Raffael Schaffrath , Sebastian Glatt
Journal: EMBO J
PubMed ID: 36102610
Doi: 10.15252/embj.2022111318
Products & Services: Gene Synthesis   
Engineering a powerful green cell factory for robust photoautotrophic diterpenoid production
Authors: Alexander Einhaus , Jasmin Steube , Robert Ansgar Freudenberg , Jonas Barczyk , Thomas Baier , Olaf Kruse
Journal: Metab Eng
PubMed ID: 35717002
Doi: 10.1016/j.ymben.2022.06.002
Products & Services: Gene Synthesis   
Sodium Accumulation in Infected Cells and Ion Transporters Mistargeting in Nodules of : Two Ugly Items That Hinder Coping with Salt Stress Effects
Authors: Natalia A Trifonova, Roman Kamyshinsky, Teodoro Coba de la Peña, Maria I Koroleva, Olga Kulikova, Victoria Lara-Dampier, Pavel Pashkovskiy, Mikhail Presniakov, José J Pueyo, M Mercedes Lucas, Elena E Fedorova
Journal: Int J Mol Sci
PubMed ID: 36142539
Doi: 10.3390/ijms231810618
Products & Services: Catalog Antibodies   
Characterizing the Contributions of Various Clostridium perfringens Enterotoxin Properties to and Permeability Effects
Authors: Archana Shrestha, Mauricio A Navarro, Juliann Beingesser, Anibal G Armien, Francisco A Uzal, Bruce A McClane
Journal: mSphere
PubMed ID: 36069435
Doi: 10.1128/msphere.00276-22
Products & Services: Plasmid DNA Preparation   
Alamandine alleviated heart failure and fibrosis in myocardial infarction mice
Authors: Kun Zhao, Tianhua Xu, Yukang Mao, Xiaoguang Wu, Dongxu Hua, Yanhui Sheng, Peng Li
Journal: Biol Direct
PubMed ID: 36167556
Doi: 10.1186/s13062-022-00338-6
Products & Services: Custom DNA/RNA Oligos   
Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
Authors: Jordan R Willis, Zachary T Berndsen, Krystal M Ma, Jon M Steichen, Torben Schiffner, Elise Landais, Alessia Liguori, Oleksandr Kalyuzhniy, Joel D Allen, Sabyasachi Baboo, Oluwarotimi Omorodion, Jolene K Diedrich, Xiaozhen Hu, Erik Georgeson, Nicole Phelps, Saman Eskandarzadeh, Bettina Groschel, Michael Kubitz, Yumiko Adachi, Tina-Marie Mullin, Nushin B Alavi, Samantha Falcone, Sunny Himansu, Andrea Carfi, Ian A Wilson, John R Yates, James C Paulson, Max Crispin, Andrew B Ward, William R Schief
Journal: Immunity
PubMed ID: 36179689
Doi: 10.1016/j.immuni.2022.09.001
Products & Services: Recombinant Antibody Expression   
Intranasal Immunization with Liposome-Displayed Receptor-Binding Domain Induces Mucosal Immunity and Protection against SARS-CoV-2
Authors: Wei-Chiao Huang, Kevin Chiem, Luis Martinez-Sobrido, Jonathan F Lovell
Journal: Pathogens
PubMed ID: 36145467
Doi: 10.3390/pathogens11091035
Products & Services: Catalog Antibodies   
Inactivated COVID-19 vaccines: durability of Covaxin/BBV152 induced immunity against variants of concern
Authors: Nathella Pavan Kumar, V V Banurekha, C P Girish Kumar, Arul Nancy, Chandrasekaran Padmapriyadarsini, Sakila Shankar, Luke Elizabeth Hanna, Manoj Murhekar, K R Uma Devi, Subash Babu
Journal: J Travel Med
PubMed ID: 35900009
Doi: 10.1093/jtm/taac088
Products & Services: Recombinant Proteins   
High-throughput T cell receptor engineering by functional screening identifies candidates with enhanced potency and specificity
Authors: Rodrigo Vazquez-Lombardi, Johanna S Jung, Fabrice S Schlatter, Anna Mei, Natalia Rodrigues Mantuano, Florian Bieberich, Kai-Lin Hong, Jakub Kucharczyk, Edo Kapetanovic, Erik Aznauryan, Cédric R Weber, Alfred Zippelius, Heinz Läubli, Sai T Reddy
Journal: Immunity
PubMed ID: 36174557
Doi: 10.1016/j.immuni.2022.09.004
Products & Services: Peptide Synthesis   
mRNA Treatment Rescues Niemann-Pick Disease Type C1 in Patient Fibroblasts
Authors: Denzil Furtado, Christina Cortez-Jugo, Ya Hui Hung, Ashley I Bush, Frank Caruso
Journal: Mol Pharm
PubMed ID: 36125338
Doi: 10.1021/acs.molpharmaceut.2c00463
Products & Services: Gene Fragments   
The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling
Authors: Manoshi Gayen, Marc R Benoit, Qingyuan Fan, Jacob Hudobenko, Riqiang Yan
Journal: J Biol Chem
PubMed ID: 36162508
Doi: 10.1016/j.jbc.2022.102532
Products & Services: Catalog Peptides   
Enhanced and Potency of a T Cell Epitope in the Ebola Virus Glycoprotein Following Amino Acid Replacement at HLA-A*02:01 Binding Positions
Authors: Sylvie Chabot, Yusra Gimie, Karam Obeid, Jaekwan Kim, Clement A Meseda, Krishnamurthy Konduru, Gerardo Kaplan, Li Sheng Fowler, Jerry P Weir, Keith Peden, Marian E Major
Journal: J Virol
PubMed ID: 36069549
Doi: 10.1128/jvi.01166-21
Products & Services: Gene Synthesis   
An albumin-angiotensin converting enzyme 2-based SARS-CoV-2 decoy with FcRn-driven half-life extension
Authors: Elisabeth Fuchs, Imke Rudnik-Jansen, Anders Dinesen, Denis Selnihhin, Ole Aalund Mandrup, Kader Thiam, Jørgen Kjems, Finn Skou Pedersen, Kenneth A Howard
Journal: Acta Biomater
PubMed ID: 36162760
Doi: 10.1016/j.actbio.2022.09.048
Products & Services: Plasmid DNA Preparation   
miR-3651 Participates in the Growth Cycle of Hepatocellular Carcinoma Cells and Promotes the Malignant Metastasis via the PI3K/AKT/mTOR Signalling Pathway
Authors: Yawei Liu, Litian Hu, Qinqiang Liu, Jing Ye, Jianping Zhang
Journal: J Oncol
PubMed ID: 36245984
Doi: 10.1155/2022/5744999
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Gene Promotes Muscle Growth and Development in Meat Ducks
Authors: Tingting Zhou, Yijing Wu, Yulin Bi, Hao Bai, Yong Jiang, Guohong Chen, Guobin Chang, Zhixiu Wang
Journal: Genes (Basel)
PubMed ID: 36140742
Doi: 10.3390/genes13091574
Products & Services: DNA Sequencing   
Chaperonin CCT5 binding with porcine parvovirus NS1 promotes the interaction of NS1 and COPƐ to facilitate viral replication
Authors: Qian Du, Xuezhi Zhang, Ning Xu, Mengyu Ma, Bicheng Miao, Yong Huang, Dewen Tong
Journal: Vet Microbiol
PubMed ID: 36126504
Doi: 10.1016/j.vetmic.2022.109574
Products & Services: Monoclonal Antibody Services   
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