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Autophagy Regulates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells Induced by Orthodontic Tension

Authors: Junyi Zheng, Bowen Xu, Kai Yang

Journal: Stem Cells Int

PubMed ID: 36248255

Doi: 10.1155/2022/2983862

Products & Services: Protein and Antibody Isolation

Author Correction: Omicron BA4/BA5 escape neutralizing immunity elicited by BA1 infection

Authors: Khadija Khan, Farina Karim, Yashica Ganga, Mallory Bernstein, Zesuliwe Jule, Kajal Reedoy, Sandile Cele, Gila Lustig, Daniel Amoako, Nicole Wolter, Natasha Samsunder, Aida Sivro, James Emmanuel San, Jennifer Giandhari, Houriiyah Tegally, Sureshnee Pillay, Yeshnee Naidoo, Matilda Mazibuko, Yoliswa Miya, Nokuthula Ngcobo, Nithendra Manickchund, Nombulelo Magula, Quarraisha Abdool Karim, Anne von Gottberg, Salim S Abdool Karim, Willem Hanekom, Bernadett I Gosnell, Richard J Lessells, Tulio de Oliveira, Mahomed-Yunus S Moosa, Alex Sigal

Journal: Nat Commun

PubMed ID: 36229444

Doi: 10.1038/s41467-022-33371-0

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Outliers Matter-Correlation between S1 IgG SARS-CoV-2 Antibodies and Neutralizing SARS-CoV-2 Antibodies

Authors: Berthold Hocher, Anne Schönbrunn, Xin Chen, Bernhard K Krämer, Volker von Baehr

Journal: Microorganisms

PubMed ID: 36296343

Doi: 10.3390/microorganisms10102067

Neutralizing Antibody Responses Among Residents and Staff of Long-Term Care Facilities in the State of New Jersey During the First Wave of the COVID-19 Pandemic

Authors: Stephen M Friedman, Jieliang Li, Pauline Thomas, Manisha Gurumurthy, Richard Siderits, Anna Nepomich, Edward Lifshitz

Journal: J Community Health

PubMed ID: 36197535

Doi: 10.1007/s10900-022-01142-z

A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology

Authors: Benjamin F N Campbell, Antje Dittmann, Birgit Dreier, Andreas Plückthun, Shiva K Tyagarajan

Journal: Elife

PubMed ID: 36314779

Doi: 10.7554/eLife.80895

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Sequential Deletions of Interferon Inhibitors MGF110-9L and MGF505-7R Result in Sterile Immunity against the Eurasia Strain of Africa Swine Fever

Authors: Mingyang Ding, Wen Dang, Huanan Liu, Keshan Zhang, Fan Xu, Hong Tian, Huaguo Huang, Zhengwang Shi, Yongjie Sunkang, Xiaodong Qin, Yong Zhang, Haixue Zheng

Journal: J Virol

PubMed ID: 36197109

Doi: 10.1128/jvi.01192-22

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miR-275/305 cluster is essential for maintaining energy metabolic homeostasis by the insulin signaling pathway in Bactrocera dorsalis

Authors: Junfei Xie, Hao Chen, Wenping Zheng, Zhaohui Cai, Xiaoxue Li, Hongyu Zhang

Journal: PLOS Genetics

Doi: 10.1371/journal.pgen.1010418

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Mannose and Hyaluronic Acid Dual-Modified Iron Oxide Enhances Neoantigen-Based Peptide Vaccine Therapy by Polarizing Tumor-Associated Macrophages

Authors: Ying Nie , Lu Shi , Yanan Zhang , Yunfei Guo , Hongchen Gu

Journal: Cancers

PubMed ID: 36291890

Doi: /10.3390/cancers14205107

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MnO Nanozyme-Mediated CRISPR-Cas12a System for the Detection of SARS-CoV-2

Authors: Lina Wu, Xinjie Wang, Xiangchuan Wu, Shiqi Xu, Ming Liu, Xizhong Cao, Taishan Tang, Xingxu Huang, He Huang

Journal: ACS Appl Mater Interfaces

PubMed ID: 36301087

Doi: 10.1021/acsami.2c14497

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FAD-Deficient P187S mutation of NAD(P)H:quinone oxidoreductase 1 (NQO1*2) binds and accelerates β-amyloid aggregation

Authors: Sudipta Panja, David Siegel, Simonetta Camandola, Rafael de Cabo, David Ross, Krishna Mallela

Journal: Biosci Rep

PubMed ID: 36281795

Doi: 10.1042/BSR20220643

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Expression changes of non-specific cytotoxic cell receptor (NCCRP1) and proliferation and migration of NCCs post-Nocardia seriolae infection in Northern Snakehead

Authors: Jian Teng, Meng Yao Cui, Yan Zhao, Hong Ju Chen, Wen Jing Du, Liang Yi Xue, Xiang Shan Ji

Journal: Dev Comp Immunol

PubMed ID: 36240859

Doi: 10.1016/j.dci.2022.104576

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Single-cell RNA sequencing analysis of shrimp immune cells identifies macrophage-like phagocytes

Authors: Peng Yang , Yaohui Chen , Zhiqi Huang , Huidan Xia , Ling Cheng , Hao Wu , Yueling Zhang , Fan Wang

Journal: Elife

PubMed ID: 36200862

Doi: 10.7554/eLife.80127

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Intracellular infection by symbiotic bacteria requires the mitotic kinase AURORA1

Authors: Jin-Peng Gao , Suyu Jiang , Yangyang Su , Ping Xu , Junjie Wang , Wenjie Liang , Cheng-Wu Liu , Jeremy D Murray

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36252014

Doi: doi.org/10.1073/pnas.2202606119

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Structural basis for product specificities of MLL family methyltransferases

Authors: Yanjing Li , Lijie Zhao , Yuebin Zhang , Ping Wu , Ying Xu , Jun Mencius , Yongxin Zheng , Xiaoman Wang , Wancheng Xu , Naizhe Huang , Xianwen Ye , Ming Lei , Pan Shi , Changlin Tian , Chao Peng , Guohui Li , Zhijun Liu , Shu Quan , Yong Chen

Journal: Mol Cell

PubMed ID: 36108631

Doi: 10.1016/j.molcel.2022.08.022

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Human melanocortin-2 receptor: Identifying a role for residues in the TM4, EC2, and TM5 domains in activation and trafficking as a result of co-expression with the accessory protein, Mrap1 in Chinese Hamster Ovary Cells.

Authors: Perry V Davis , Ciaran A Shaughnessy , Robert M Dores

Journal: Biomolecules

PubMed ID: 36291631

Doi: 10.3390/biom12101422

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Labeling Ebola Virus with a Self-Splicing Fluorescent Reporter

Authors: Baylee Heiden , Elke Mühlberger , Christopher W Lennon , Adam J Hume

Journal: Microorganisms

PubMed ID: 36363701

Doi: 10.3390/microorganisms10112110

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Advanced pathway engineering for phototrophic putrescine production

Authors: Robert A Freudenberg , Luisa Wittemeier , Alexander Einhaus , Thomas Baier , Olaf Kruse

Journal: Plant Biotechnol J

PubMed ID: 35748533

Doi: 10.1111/pbi.13879

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Crystal structure of an L-type lectin domain from archaea

Authors: Farha Khan, Kaza Suguna

Journal: Proteins

PubMed ID: 36301308

Doi: 10.1002/prot.26440

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Authors: Eyby Leon, Claris Nde, Randall S Ray, Diego Preciado, Irene E Zohn

Journal: Am J Med Genet A

PubMed ID: 36263470

Doi: 10.1002/ajmg.a.62991

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Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2

Authors: Phillip Pymm, Samuel J Redmond, Olan Dolezal, Francesca Mordant, Ester Lopez, James P Cooney, Kathryn C Davidson, Ebene R Haycroft, Chee Wah Tan, Rebecca Seneviratna, Samantha L Grimley, Damian F J Purcell, Stephen J Kent, Adam K Wheatley, Lin-Fa Wang, Andrew Leis, Alisa Glukhova, Marc Pellegrini, Amy W Chung, Kanta Subbarao, Adam P Uldrich, Wai-Hong Tham, Dale I Godfrey, Nicholas A Gherardin

Journal: iScience

PubMed ID: 36213007

Doi: 10.1016/j.isci.2022.105259

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SARS-CoV-2 Transmission from Human to Pet and Suspected Transmission from Pet to Human, Thailand

Authors: Chutchai Piewbang, Panida Poonsin, Pattiya Lohavicharn, Sabrina Wahyu Wardhani, Wichan Dankaona, Jiratchaya Puenpa, Yong Poovorawan, Somporn Techangamsuwan

Journal: J Clin Microbiol

PubMed ID: 36314788

Doi: 10.1128/jcm.01058-22

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Divergent SARS-CoV-2-specific T cell responses in intensive care unit workers following mRNA COVID-19 vaccination

Authors: Estefanía Salgado Del Riego, María Laura Saiz, Viviana Corte-Iglesias, Blanca Leoz Gordillo, Cristina Martin-Martin, Mercedes Rodríguez-Pérez, Dolores Escudero, Carlos Lopez-Larrea, Beatriz Suarez-Alvarez

Journal: Front Immunol

PubMed ID: 36275696

Doi: 10.3389/fimmu.2022.942192

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Antibody Response to Rotavirus C Pre-Farrow Natural Planned Exposure to Gilts and Their Piglets

Authors: Deepak Kumar, Amanda V Anderson, Jeremy Pittman, Nora L Springer, Douglas G Marthaler, Waithaka Mwangi

Journal: Viruses

PubMed ID: 36298806

Doi: 10.3390/v14102250

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The Therapeutic Effects of a PEDF-Derived Short Peptide on Murine Experimental Dry Eye Involves Suppression of MMP-9 and Inflammation

Authors: Tsung-Chuan Ho, Nai-Wen Fan, Shu-I Yeh, Show-Li Chen, Yeou-Ping Tsao

Journal: Transl Vis Sci Technol

PubMed ID: 36201200

Doi: 10.1167/tvst.11.10.12

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Efficacy and safety of universal (TCRKO) ARI-0001 CAR-T cells for the treatment of B-cell lymphoma

Authors: Noelia Maldonado-Pérez, María Tristán-Manzano, Pedro Justicia-Lirio, Elena Martínez-Planes, Pilar Muñoz, Kristina Pavlovic, Marina Cortijo-Gutiérrez, Carlos Blanco-Benítez, María Castella, Manel Juan, Mathias Wenes, Pedro Romero, Francisco J Molina-Estévez, Concepción Marañón, Concha Herrera, Karim Benabdellah, Francisco Martin

Journal: Front Immunol

PubMed ID: 36275777

Doi: 10.3389/fimmu.2022.1011858

Products & Services: Recombinant Antibody Expression

CD8+ T cell clonotypes from prior SARS-CoV-2 infection predominate during the cellular immune response to mRNA vaccination

Authors: Emily S Ford, Koshlan Mayer-Blackwell, Lichen Jing, Anton M Sholukh, Russell St Germain, Emily L Bossard, Hong Xie, Thomas H Pulliam, Saumya Jani, Stacy Selke, Carlissa J Burrow, Christopher L McClurkan, Anna Wald, Michael R Holbrook, Brett Eaton, Elizabeth Eudy, Michael Murphy, Elena Postnikova, Harlan S Robins, Rebecca Elyanow, Rachel M Gittelman, Matyas Ecsedi, Elise Wilcox, Aude G Chapuis, Andrew Fiore-Gartland, David M Koelle

Journal: Res Sq

PubMed ID: 36263073

Doi: 10.21203/rs.3.rs-2146712/v1

Products & Services: Codon Optimization

A bZIP transcription factor (CiFD) regulates drought and low temperature induced flowering by alternative splicing in citrus

Authors: Li-Xia Ye, Yan-Mei Wu, Jin-Xia Zhang, Jin-Xin Zhang, Huan Zhou, Ren-Fang Zeng, Wei-Xuan Zheng, Mei-Qi Qiu, Jing-Jing Zhou, Zong-Zhou Xie, Chun-Gen Hu, Jin-Zhi Zhang

Journal: J Integr Plant Biol

PubMed ID: 36250511

Doi: 10.1111/jipb.13390

Products & Services: Gene Fragments

Blocking Autophagy in M1 Macrophages Enhances Virus Replication and Eye Disease in Ocularly Infected Transgenic Mice

Authors: Ujjaldeep Jaggi, Harry H Matundan, Dhong Hyun Lee, Homayon Ghiasi

Journal: J Virol

PubMed ID: 36286481

Doi: 10.1128/jvi.01401-22

Products & Services: Mammalian Expression

Epitope of antiphospholipid antibodies retrieved from peptide microarray based on R39-R43 of β2-glycoprotein I

Authors: Marc Moghbel, Aline Roth, Daniela Baptista, Kapka Miteva, Fabienne Burger, Fabrizio Montecucco, Nicolas Vuilleumier, François Mach, Karim J Brandt

Journal: Res Pract Thromb Haemost

PubMed ID: 36304483

Doi: 10.1002/rth2.12828

Products & Services: Monoclonal Antibody Services

Apigenin suppresses mycoplasma-induced alveolar macrophages necroptosis via enhancing the methylation of TNF-α promoter by PPARγ-Uhrf1 axis

Authors: Xiuzhen Mei, Jian Wang, Chao Zhang, Jiale Zhu, Beibei Liu, Qingyun Xie, Ting Yuan, Yuzi Wu, Rong Chen, Xing Xie, Yanna Wei, Li Wang, Guoqing Shao, Qiyan Xiong, Yefen Xu, Zhixin Feng, Zhenzhen Zhang

Journal: Phytomedicine

PubMed ID: 36332388

Doi: 10.1016/j.phymed.2022.154504

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Combining mass spectrometry and machine learning to discover bioactive peptides

Authors: Christian T Madsen, Jan C Refsgaard, Felix G Teufel, Sonny K Kjærulff, Zhe Wang, Guangjun Meng, Carsten Jessen, Petteri Heljo, Qunfeng Jiang, Xin Zhao, Bo Wu, Xueping Zhou, Yang Tang, Jacob F Jeppesen, Christian D Kelstrup, Stephen T Buckley, Søren Tullin, Jan Nygaard-Jensen, Xiaoli Chen, Fang Zhang, Jesper V Olsen, Dan Han, Mads Grønborg, Ulrik de Lichtenberg

Journal: Nat Commun

PubMed ID: 36266275

Doi: 10.1038/s41467-022-34031-z

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Observation of conformational changes that underlie the catalytic cycle of Xrn2

Authors: Jan H Overbeck, David Stelzig, Anna-Lisa Fuchs, Jan Philip Wurm, Remco Sprangers

Journal: Nature Chemical Biology

PubMed ID: 36008487

Doi: 10.1038/s41589-022-01111-6

Products & Services: Codon Optimization Gene Synthesis

Functional EGF domain of the human neuregulin 1α produced in Escherichia coli with accurate disulfide bonds

Authors: Arthur Schveitzer Ferreira, Amanda Lopacinski, Michel Batista, Priscila Mazzocchi Hiraiwa, Natalia Fernanda Bueno, Beatriz Gomes Guimarães, Nilson I T Zanchin

Journal: Mol Biol Rep

PubMed ID: 36198848

Doi: 10.1007/s11033-022-07956-3

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Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation

Authors: Yoshibumi Ueda, Yuri Miura, Nario Tomishige, Naotoshi Sugimoto, Megumi Murase, Genki Kawamura, Norihiko Sasaki, Toshiyuki Ishiwata, Takeaki Ozawa

Journal: Cell Chem Biol

PubMed ID: 36288730

Doi: 10.1016/j.chembiol.2022.10.002

Products & Services: Mammalian Expression

The Antimicrobial Peptide LJ-hep2 from Exerting Activities against Multiple Pathogenic Bacteria and Immune Protection In Vivo

Authors: Ruihao Gong, Zhe An, Weibin Zhang, Fangyi Chen, Ke-Jian Wang

Journal: Mar Drugs

PubMed ID: 36286474

Doi: 10.3390/md20100651

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Focused B cell response to recurring gluten motif with implications for epitope spreading in celiac disease

Authors: Chunyan Zhou, Thomas Østerbye, Emil Bach, Shiva Dahal-Koirala, Lene S Høydahl, Øyvind Steinsbø, Jørgen Jahnsen, Knut E A Lundin, Søren Buus, Ludvig M Sollid, Rasmus Iversen

Journal: Cell Rep

PubMed ID: 36288703

Doi: 10.1016/j.celrep.2022.111541

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Deciphering the Key Regulatory Roles of KLF6 and Bta-miR-148a on Milk Fat Metabolism in Bovine Mammary Epithelial Cells

Authors: Ambreen Iqbal, Haibin Yu, Ping Jiang, Zhihui Zhao

Journal: Genes (Basel)

PubMed ID: 36292712

Doi: 10.3390/genes13101828

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Investigating the Role of African Horse Sickness Virus VP7 Protein Crystalline Particles on Virus Replication and Release

Authors: Shani Bekker, Christiaan A Potgieter, Vida van Staden, Jacques Theron

Journal: Viruses

PubMed ID: 36298748

Doi: 10.3390/v14102193

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Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-β-mannans

Authors: Marcele P Martins, Mariana A B Morais, Gabriela F Persinoti, Rafael H Galinari, Li Yu, Yoshihisa Yoshimi, Fernanda B Passos Nunes, Tatiani B Lima, Shayla F Barbieri, Joana L M Silveira, Vincent Lombard, Nicolas Terrapon, Paul Dupree, Bernard Henrissat, Mário T Murakami

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 36322419

Doi: 10.1107/S2059798322009561

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MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases

Authors: Zahra Mohtashami, Mithalesh K Singh, Nasim Salimiaghdam, Mustafa Ozgul, M Cristina Kenney

Journal: Int J Mol Sci

PubMed ID: 36233287

Doi: 10.3390/ijms231911991

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Inhibition of intermittent calcium-activated potassium channel (SK4) attenuates Ang II-induced hypertrophy of human-induced stem cell-derived cardiomyocytes via targeting Ras-Raf-MEK1/2-ERK1/2 and CN-NFAT signaling pathways

Authors: Hongyi Zhao, Xi Wang, Yanhong Tang, Qingyan Zhao, Congxin Huang

Journal: Cell Biol Int

PubMed ID: 36273427

Doi: 10.1002/cbin.11948

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Engineering Self-Assembled Endolysin Nanoparticles against Antibiotic-Resistant Bacteria

Authors: Christian K O Dzuvor, Bhuvana K Shanbhag, Tayyaba Younas, Hsin-Hui Shen, Victoria S Haritos, Lizhong He

Journal: ACS Appl Bio Mater

PubMed ID: 36194892

Doi: 10.1021/acsabm.2c00741

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Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains

Authors: Xingxing Chen, Yize Sun, Laiqiang Chen, Xiu-Sheng Chen, Mingtian Pan, Yiran Zhang, Qi Wang, Weili Yang, Peng Yin, Dajian He, Xiangyu Guo, Su Yang, Yan Zeng, Sen Yan, Xiao-Jiang Li, Shihua Li

Journal: Cell Mol Life Sci

PubMed ID: 36251080

Doi: 10.1007/s00018-022-04577-8

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Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose)

Authors: Jijin R A Kuttiyatveetil, Heddy Soufari, Morgan Dasovich, Isabel R Uribe, Manija Mirhasan, Shang-Jung Cheng, Anthony K L Leung, John M Pascal

Journal: Cell Rep

PubMed ID: 36288691

Doi: 10.1016/j.celrep.2022.111529

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Reverse genetics based H5N2 vaccine provides clinical protection against H5N1, H5N8 and H9N2 avian influenza infection in chickens

Authors: Sivasankar Panickan, Sandeep Bhatia, Sushant Bhat, Nisha Bhandari, Atul Kumar Pateriya, Semmannan Kalaiyarasu, Richa Sood, Meghna Tripathi

Journal: Vaccine

PubMed ID: 36374710

Doi: 10.1016/j.vaccine.2022.10.018

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Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins

Authors: Michael D Healy, Joanna Sacharz, Kerrie E McNally, Calum McConville, Vikas A Tillu, Ryan J Hall, Molly Chilton, Peter J Cullen, Mehdi Mobli, Rajesh Ghai, David A Stroud, Brett M Collins

Journal: Structure

PubMed ID: 36302387

Doi: 10.1016/j.str.2022.10.001

Products & Services: Mammalian Expression

Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant

Authors: Wei Zhang, Ke Shi, Qibin Geng, Gang Ye, Hideki Aihara, Fang Li

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36256797

Doi: 10.1073/pnas.2206509119

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CD4-1 and CD8α T lymphocytes subsets in spotted sea bass (Lateolabrax maculatus) and comparison on antigenicity of T lymphocytes subsets in other three marine fish species

Authors: Xiaoyu Jiang, Jing Xing, Xiaoqian Tang, Xiuzhen Sheng, Heng Chi, Wenbin Zhan

Journal: Fish Shellfish Immunol

PubMed ID: 36210001

Doi: 10.1016/j.fsi.2022.10.004

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Velcrin-induced selective cleavage of tRNA(TAA) by SLFN12 causes cancer cell death

Authors: Sooncheol Lee, Stephanie Hoyt, Xiaoyun Wu, Colin Garvie, Joseph McGaunn, Mrinal Shekhar, Marcus Tötzl, Matthew G Rees, Andrew D Cherniack, Matthew Meyerson, Heidi Greulich

Journal: Nat Chem Biol

PubMed ID: 36302897

Doi: 10.1038/s41589-022-01170-9

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Loss of Chemerin in Rhabdomyosarcoma Cells Polarizes Adjacent Monocytes to an Immunosuppressive Phenotype

Authors: Rui Sun, Jia Le Lin, Man Si Cheng, Kang Yi Lee, Thilo Spruss, Christa Buechler, Herbert Schwarz

Journal: Biomedicines

PubMed ID: 36289872

Doi: 10.3390/biomedicines10102610

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