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From Multi-Species Screening to Targeted Investigation: Discovery of ACE Inhibitory Peptides in Gigantidas platifrons via Peptidomics, Virtual Screening, and Molecular Dynamics Simulations

Authors: Haorui Zhang; Yuhong Ouyang; Qishan Suo; Hao Chen; Jie Cui; Yang Yue

Journal: Molecules

PubMed ID: 41828750

Doi: 10.3390/molecules31050757

Products & Services: Peptide Synthesis

SnRK2.5-mediated phosphorylation of PIN2 links osmotic stress signaling with auxin dependent root adaptive growth in Arabidopsis

Authors: Shujuan Zhang, Zilong Cui, Yu Gao, Qi Liao, Wenyan Li, Siqi Yuan, Zhuomeng Li, Xinwen Zhang, Kai Ding, Wenjing Zhang, Like Shen, Jörg Kudla, Wenhua Zhang, Jing Zhang, Qun Zhang

Journal: Molecular Plant

PubMed ID: 41353562

Doi: 10.1016/j.molp.2025.12.002

Products & Services: Protein and Antibody Isolation Catalog Antibodies

Discovery of novel pyrrolidine-2,5-dione scaffold PICK1 PDZ inhibitors as anti-ischemic stroke agents

Authors: Yichen Jiang, Qi Liu, Ting Zhu, Ruiguo Liang, Yujiao Qin, Xiya Guo, Jiacheng Wang, Ping Li, Jie Zhou, Han Ju, Mingxin Dong

Journal: European Journal of Medicinal Chemistry

PubMed ID: 41386205

Doi: 10.1016/j.ejmech.2025.118410

Products & Services: Plasmid DNA Preparation

Native cell niche-inspired multiorder nanoassemblies orchestrate integrated interaction networks to guide muscle regeneration

Authors: Peng Lou, Yizhuo Wang, Yimeng Zhang, Xiyue Zhou, Lan Li, Shuyun Liu, Meihua Wan, Yanrong Lu, Jingping Liu

Journal: Molecular therapy: the journal of the American Society of Gene Therapy

PubMed ID: 41445187

Doi: 10.1016/j.ymthe.2025.12.044

Products & Services: Catalog IVT RNA products Custom mRNA synthesis

The Artemisia argyi oil reduces high-fat diet-induced obesity by enhancing thermogenesis in brown adipose tissue

Authors: Shuai Wang, ShengLan Lin, Fuan Xie, Shuting Liu, Ting He, Kun Chen, Zhengrong Huang, Wenlong Xie, Hongqiu Cheng, Jian Zhang, Weihua Li

Journal: NPJ science of food

PubMed ID: 41390517

Doi: 10.1038/s41538-025-00633-2

Products & Services: Molecular Biology Reagents Catalog Antibodies

The extracellular domain of mGluR6 regulates targeting to the conventional secretion pathway

Authors: Andrew P Rideout, Omar W Abuelatta, Melina A Agosto

Journal: Molecular and cellular neurosciences

PubMed ID: 41448371

Doi: 10.1016/j.mcn.2025.104068

Products & Services: Protein and Antibody Isolation

Human Substance P Interactions with G Protein-Coupled Receptor NK1R Observed by NMR in Solution

Authors: Haoyi Ge, Lingyun Yang, Changran Chen, Yuxin Xu, Dongsheng Liu, Kurt Wüthrich

Journal: Journal of the American Chemical Society

PubMed ID: 41264783

Doi: doi.org/10.1021/jacs.5c12553

Products & Services: Peptide Synthesis

Far-red light orchestrates antiviral defense in plants

Authors: Qian Gong, Linfang He, Fan Huang, Yunjing Wang, Jinchuan Xie, Yiguo Hong, Yule Liu

Journal: SCIENCE ADVANCES

PubMed ID: 41259508

Doi: 10.1126/sciadv.adz7663

Products & Services: Protein and Antibody Isolation

CSF3 enhances the innate immune responses to ALV-J infections via NF-κB and interferon pathways

Authors: Junliang Xia, Weiding Chen, Chengxun Xu, Meihuizi Wang, Guodong Mo, Xiquan Zhang

Journal: Poultry Science

PubMed ID: 40812136

Doi: 10.1016/j.psj.2025.105648

Products & Services: Plasmid DNA Preparation

Modeling and addressing on-target/off-tumor toxicity of claudin 18.2 targeted immunotherapies

Authors: Elizabeth J Carstens, Kazuki Takahashi, Naoya Sakamoto, Martina De Vizio, Micaela Morgado, Shahryar Khoshtinat Nikkhoi, Abhishek Mangipudi, Canh Hiep Nguyen, Tate Weltzin, Izuma Nakayama, Qiang Lv, Jue Zeng, Cui Nie, Changjing Deng, Xiaoxiao Wang, Lile Liu, Samuel J Klempner, Anusuya Ramasubramanian, Jonathan A Nowak, Andrew J Aguirre, Kohei Shitara, Eric L Smith

Journal: Nature Communications

PubMed ID: 41176582

Doi: 10.1038/s41467-025-65148-6.

Products & Services: Recombinant Proteins