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Organ-specific delivery of an mRNA-encoded bispecific T cell engager targeting glypican-3 in hepatocellular carcinoma
Authors: Yan Huang, Shaoli Liu, Xiaoju Zhang, Bingxu Zhang, Feng Shi, Jia Zhang, Shuaibo Shao, Hongya Han, Xiaoyun Ma, Jing Xie, Jianqi Zhang, Hongxiaoying Yu, Yongchao Zhao, Jiazheng Jin, Dong Xu, Liang Liu, Jianing Wang, Yu Tan, Kelu Xu, Lushuai Jin, Quanjun Du, Yifeng Geng, Andong Liu, Wei Xu
Journal: Nature Communications
PubMed ID: 41397962
Doi: 10.1038/s41467-025-66087-y
Products & Services: Custom Vector Construction   
Molecular insights into ligand recognition and signaling of OXGR1
Authors: Aijun Liu, Yezhou Liu, Yuanzhengyang Long, Richard D Ye
Journal: Nature Communications
PubMed ID: 41413034
Doi: 10.1038/s41467-025-67101-z
Products & Services: Protein and Antibody Isolation   
Semi-inductive dataset construction and framework optimization for practical drug target interaction prediction with ScopeDTI
Authors: Yigang Chen; Xiang Ji; Ziyue Zhang; Zihao Zhu; Yuming Zhou; Chang Su; Yang-Chi-Dung Lin; Hsi-Yuan Huang; Kangping Wei; Yi Lai; Ke Chen; Xingqiao Lin; Yangyi Zhang; Jiehui Fu; Yixian Huang; Shidong Cui; Shih-Chung Yen; Tao Zhang; Arieh Warshel; Hsien-Da Huang
Journal: Nature Communications
PubMed ID: 41390462
Doi: 10.1038/s41467-025-66311-9
Products & Services: Protein Electrophoresis and Western   
Structural basis of Neisseria meningitidis quinol dependent nitric oxide reductase activation by dimerization
Authors: Chai C. Gopalasingam; Haruka Egami; Hideki Shigematsu; Masatora Sakaue; Kouki Fukumoto; Christoph Gerle; Masaki Yamamoto; Yoshitsugu Shiro; Kazumasa Muramoto; Takehiko Tosha
Journal: Communications Biology
PubMed ID: 41896389
Doi: 10.1038/s42003-026-09754-0
Products & Services: Plasmid DNA Preparation   
From Multi-Species Screening to Targeted Investigation: Discovery of ACE Inhibitory Peptides in Gigantidas platifrons via Peptidomics, Virtual Screening, and Molecular Dynamics Simulations
Authors: Haorui Zhang; Yuhong Ouyang; Qishan Suo; Hao Chen; Jie Cui; Yang Yue
Journal: Molecules
PubMed ID: 41828750
Doi: 10.3390/molecules31050757
Products & Services: Peptide Synthesis   
Nuclear effects play an important role in determining codon usage-dependent human gene expression
Authors: Renu Garg, Pancheng Xie, Jiabin Duan, Huan Liu, Yi Liu
Journal: Nature Communications
PubMed ID: 41339630
Doi: 10.1038/s41467-025-65907-5
Products & Services: Gene Synthesis   
Structural basis of microtubule-mediated signal transduction
Authors: Sung Ryul Choi, Thorsten B Blum, Matteo Giono, Bibhas Roy, Ioannis Vakonakis, Dominic Schmid, Nicole Oelgarth, Apisha Ranganathan, Alvar D Gossert, G V Shivashankar, Alfred Zippelius, Michel O Steinmetz
Journal: Cell
PubMed ID: 41365297
Doi: 10.1016/j.cell.2025.11.011
Personalized CRISPR knock-in cytokine gene therapy to remodel the tumor microenvironment and enhance CAR T cell therapy in solid tumors
Authors: Michael Launspach, Julia Macos, Shoaib Afzal, Janik Hohmann, Marc L Appis, Maximilian Pilgram, Stefanie Beez, Emily Ohlendorf, Casper F T van der Ven, Chahrazad Lachiheb, Karin Töws, Lena Andersch, Marvin Jens, Felix Zirngibl, Jonas Kath, Maria Stecklum, Elias Rodriguez-Fos, Kathleen Anders, Dimitrios L Wagner, Anton G Henssen, Ralf Kühn, Angelika Eggert, Annette Künkele
Journal: Nature Communications
PubMed ID: 41366257
Doi: 10.1038/s41467-025-67328-w
A highly active Burkholderia polyketoacyl-CoA thiolase for production of triacetic acid lactone
Authors: Zilong Wang, Seokjung Cheong, Jose Henrique Pereira, Weixi Hu, Yifan Guo, Andy DeGiovanni, Guangxu Lan, Jinho Kim, Robert W Haushalter, Taek Soon Lee, Paul D Adams, Jay D Keasling
Journal: Nature Communications
PubMed ID: 41365852
Doi: 10.1038/s41467-025-65946-y
Geminin inhibits DNA replication licensing by sterically blocking CDT1-MCM2 interactions
Authors: Joshua Tomkins, Lucy V Edwardes, Sarah V Faull, Matthew Peach, Peter J Gillespie, Vera Leber, Anna Schmidt, Halil Bounoua, Nicholas Sim, Rosa Camarillo, J Julian Blow, Alexis R Barr, Anna Barnard, Christian Speck
Journal: Nature Communications
PubMed ID: 41365879
Doi: 10.1038/s41467-025-67073-0
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